CS197990A2 - Dipeptide's derivatives that inhibit enzymes' effect - Google Patents

Dipeptide's derivatives that inhibit enzymes' effect

Info

Publication number
CS197990A2
CS197990A2 CS901979A CS197990A CS197990A2 CS 197990 A2 CS197990 A2 CS 197990A2 CS 901979 A CS901979 A CS 901979A CS 197990 A CS197990 A CS 197990A CS 197990 A2 CS197990 A2 CS 197990A2
Authority
CS
Czechoslovakia
Prior art keywords
dipeptide
derivatives
effect
inhibit enzymes
enzymes
Prior art date
Application number
CS901979A
Other languages
Czech (cs)
Inventor
Wolf-Ulrich Dr Nickel
Wolfgang Dr Linz
Dieter Dr Ruppert
Hansjorg Dr Urbach
Adalbert Dr Wagner
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of CS197990A2 publication Critical patent/CS197990A2/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06078—Dipeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CS901979A 1989-04-22 1990-04-20 Dipeptide's derivatives that inhibit enzymes' effect CS197990A2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3913272A DE3913272A1 (en) 1989-04-22 1989-04-22 DIPEPTIDE DERIVATIVES WITH ENZYME-INHIBITOR EFFECT

Publications (1)

Publication Number Publication Date
CS197990A2 true CS197990A2 (en) 1991-08-13

Family

ID=6379220

Family Applications (1)

Application Number Title Priority Date Filing Date
CS901979A CS197990A2 (en) 1989-04-22 1990-04-20 Dipeptide's derivatives that inhibit enzymes' effect

Country Status (18)

Country Link
EP (1) EP0394853A1 (en)
JP (1) JPH02295998A (en)
KR (1) KR900016255A (en)
CN (1) CN1047084A (en)
AU (1) AU622015B2 (en)
CA (1) CA2015070A1 (en)
CS (1) CS197990A2 (en)
DE (1) DE3913272A1 (en)
FI (1) FI901957A0 (en)
HU (1) HU205770B (en)
IL (1) IL94144A0 (en)
MA (1) MA21812A1 (en)
MX (1) MX20405A (en)
NO (1) NO901759L (en)
NZ (1) NZ233391A (en)
PT (1) PT93797A (en)
RU (1) RU1836382C (en)
ZA (1) ZA902995B (en)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8929070D0 (en) * 1989-12-22 1990-02-28 Fujisawa Pharmaceutical Co Peptide compounds,processes for preparation thereof and pharmaceutical composition comprising the same
TW209870B (en) * 1990-01-18 1993-07-21 Pfizer
US6313094B1 (en) 1990-12-11 2001-11-06 Japan Energy Corporation β-amino-α-hydroxycarboxylic acid derivatives and HIV protease inhibitors
PL294866A1 (en) * 1991-06-21 1993-05-31 Hoechst Ag Method of obtaining novel rennin redtarding heterocyclic compounds
PL294870A1 (en) * 1991-06-21 1993-02-08 Hoechst Ag
US5554728A (en) * 1991-07-23 1996-09-10 Nexstar Pharmaceuticals, Inc. Lipid conjugates of therapeutic peptides and protease inhibitors
US5271644A (en) * 1991-08-29 1993-12-21 Canadian Bank Note Company, Limited Security device comprising optically variable data and method for making the same
US6071895A (en) * 1992-03-11 2000-06-06 Narhex Limited Polar-substituted hydrocarbons
DE69333270T2 (en) 1992-03-11 2004-08-05 Narhex Ltd. AMINE DERIVATIVES OF OXO AND HYDROXY SUBSTITUTED CARBON HYDROGEN
RU2126794C1 (en) * 1992-03-11 1999-02-27 Нархекс Лимитед Amino-derivatives of oxo- or hydroxy-substituted hydrazines, method of their synthesis and pharmaceutical compositions for inhibition of retrovirus protease
US5888992A (en) * 1992-03-11 1999-03-30 Narhex Limited Polar substituted hydrocarbons
IL110898A0 (en) * 1993-09-10 1994-11-28 Narhex Australia Pty Ltd Polar-substituted hydrocarbons
US6222043B1 (en) 1995-06-30 2001-04-24 Japan Energy Corporation Methods of preparing novel dipeptide compounds or pharmaceutically acceptable salts thereof
CA2179935C (en) * 1995-06-30 2010-09-07 Ryohei Kato Novel dipeptide compound or pharmaceutically acceptable salt thereof and medical use thereof
CA2249747A1 (en) 1996-12-27 1998-07-09 Tsutomu Mimoto Novel tripeptide compounds and anti-aids drugs
CN105712935A (en) * 2014-12-04 2016-06-29 黄冈银河阿迪药业有限公司 Preparation method of 1-propyl-2-methylimidazole
CN109187806A (en) * 2018-10-22 2019-01-11 嘉兴迈维代谢生物科技有限公司 A kind of general quality control method of liquid chromatograph mass spectrography metabolism group detection

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4499079A (en) * 1982-11-18 1985-02-12 E. R. Squibb & Sons, Inc. Carboxy and substituted carboxy alkanoyl and cycloalkanoyl peptides
ZA87563B (en) * 1986-02-03 1987-09-30 Squibb & Sons Inc N-heterocyclic alcohol renin inhibitors
DE3627877A1 (en) * 1986-07-30 1988-02-04 Hoechst Ag RENINE-INHIBITING DI- AND TRIPEPTIDES, METHOD FOR THE PRODUCTION THEREOF, THESE AGENTS AND THEIR USE

Also Published As

Publication number Publication date
CN1047084A (en) 1990-11-21
EP0394853A1 (en) 1990-10-31
ZA902995B (en) 1990-12-28
NO901759L (en) 1990-10-23
IL94144A0 (en) 1991-01-31
DE3913272A1 (en) 1990-10-25
AU5371690A (en) 1990-11-08
RU1836382C (en) 1993-08-23
HU902505D0 (en) 1990-08-28
NZ233391A (en) 1993-08-26
KR900016255A (en) 1990-11-13
AU622015B2 (en) 1992-03-26
JPH02295998A (en) 1990-12-06
CA2015070A1 (en) 1990-10-22
PT93797A (en) 1990-11-20
NO901759D0 (en) 1990-04-20
HU205770B (en) 1992-06-29
MX20405A (en) 1993-08-01
HUT54384A (en) 1991-02-28
FI901957A0 (en) 1990-04-19
MA21812A1 (en) 1990-12-31

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