CR20150391A - DERIVATIVES 2 - ((4-AMINO-3- (3-FLUORO-5-HIDROXIFENILO) -1H-PIRAZOLO [3,4-D] PIRIMIDIN-1-IL) METHYL) -3- (2- (TRIFLUORO-METHYL) BENCILO) QUINAZOLIN-4 (3H) -ONA AND ITS USE AS QUINASE-3 PHOSFOINOSITIDA INHIBITORS - Google Patents

DERIVATIVES 2 - ((4-AMINO-3- (3-FLUORO-5-HIDROXIFENILO) -1H-PIRAZOLO [3,4-D] PIRIMIDIN-1-IL) METHYL) -3- (2- (TRIFLUORO-METHYL) BENCILO) QUINAZOLIN-4 (3H) -ONA AND ITS USE AS QUINASE-3 PHOSFOINOSITIDA INHIBITORS

Info

Publication number
CR20150391A
CR20150391A CR20150391A CR20150391A CR20150391A CR 20150391 A CR20150391 A CR 20150391A CR 20150391 A CR20150391 A CR 20150391A CR 20150391 A CR20150391 A CR 20150391A CR 20150391 A CR20150391 A CR 20150391A
Authority
CR
Costa Rica
Prior art keywords
methyl
phosfoinositida
hidroxifenilo
bencilo
quinase
Prior art date
Application number
CR20150391A
Other languages
Spanish (es)
Inventor
Rudy Laurent Maria Broeckx
Alex Herman Copmans
Alun John Smith
David Michel Adrien Taddei
Stuart Thomas Onions
Original Assignee
Respivert Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Respivert Ltd filed Critical Respivert Ltd
Publication of CR20150391A publication Critical patent/CR20150391A/en

Links

Landscapes

  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

La presente invención se refiere, inter alia, a un compuesto de la fórmula (I), y a composiciones que comprenden el compuesto, y al uso de los compuestos y composiciones de los compuestos en el tratamiento, por ejemplo, en el tratamiento de enfermedades inflamatorias, en particular, enfermedades inflamatorias respiratorias. La invención además se extiende a métodos de elaboración de dichos compuestos.The present invention relates, inter alia, to a compound of the formula (I), and to compositions comprising the compound, and to the use of the compounds and compositions of the compounds in the treatment, for example, in the treatment of inflammatory diseases. , in particular, inflammatory respiratory diseases. The invention further extends to methods of making said compounds.

CR20150391A 2013-03-15 2015-07-27 DERIVATIVES 2 - ((4-AMINO-3- (3-FLUORO-5-HIDROXIFENILO) -1H-PIRAZOLO [3,4-D] PIRIMIDIN-1-IL) METHYL) -3- (2- (TRIFLUORO-METHYL) BENCILO) QUINAZOLIN-4 (3H) -ONA AND ITS USE AS QUINASE-3 PHOSFOINOSITIDA INHIBITORS CR20150391A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP13275070 2013-03-15
EP13193372 2013-11-18
GB201450770 2014-03-14

Publications (1)

Publication Number Publication Date
CR20150391A true CR20150391A (en) 2015-08-28

Family

ID=54337484

Family Applications (1)

Application Number Title Priority Date Filing Date
CR20150391A CR20150391A (en) 2013-03-15 2015-07-27 DERIVATIVES 2 - ((4-AMINO-3- (3-FLUORO-5-HIDROXIFENILO) -1H-PIRAZOLO [3,4-D] PIRIMIDIN-1-IL) METHYL) -3- (2- (TRIFLUORO-METHYL) BENCILO) QUINAZOLIN-4 (3H) -ONA AND ITS USE AS QUINASE-3 PHOSFOINOSITIDA INHIBITORS

Country Status (1)

Country Link
CR (1) CR20150391A (en)

Similar Documents

Publication Publication Date Title
NI201500134A (en) DERIVATIVES OF 2 - ((4-AMINO-3- (3-FLUORO-5-HYDROXYPHENIL) -1H-PIRAZOLO [3,4-D] PYRIMIDIN-1-IL) METHYL) -3- (2- (TRIFLUOROMETHYL) BENZYL ) QUINAZOLINE-4 (3H) -ONE AND ITS USE AS INHIBITORS OF PHOSPHOINOSITIDE 3-KINASES
UY33337A (en) SUBSTITUTED DERIVATIVES OF 1H-PIRAZOL [3,4-d] PYRIMIDINE AS INHIBITORS OF PHOSFOINOSITIDE 3-KINASES
CL2017002650A1 (en) Novel compounds
NI201200061A (en) DERIVATIVES OF QUINAZOLINE-4 (3H) -ONE USED AS INHIBITORS OF PI3 KINASE
SV2016005229A (en) SYK INHIBITORS
CR20200276A (en) SULFAMOYLARYLAMIDES AND THEIR USE AS MEDICINES FOR THE TREATMENT OF HEPATITIS B (DIVISIONAL EXP. 2015-0059)
CR20190156A (en) Bipyrazole derivatives as jak inhibitors
HN2012000263A (en) DERIVATIVES N1-SULFONIL-5-FLUOROPIRIMIDINONA
CR20150447A (en) NEW DERIVATIVES OF PIRAZOL
BR112014005226A2 (en) benzonitrile derivatives as kinase inhibitors
BR112016007356A2 (en) herbicidal compounds
NI201300111A (en) PYRAZOLOSPIROKETONE DERIVATIVES FOR USE AS ACETYL-COA CARBOXYLASE INHIBITORS
CR20150378A (en) TETRACYCLIC COMPOUNDS REPLACED WITH HETEROCICLE AND METHODS OF USE OF THE SAME FOR THE TREATMENT OF VIVIC DISEASES
BR112015029462A8 (en) KINASE INHIBITORS
CL2017002856A1 (en) Thioether compounds as nitrification inhibitors
UY37015A (en) INHIBITORS OF BRUTON TYROSINE KINASE AND METHODS OF USE
GT201500235A (en) ESTRA -1,3,5 (10), 16- TETRAENE -3-CARBOXAMIDS FOR THE INHIBITION OF THE 17B-HYDROXIESTEROID DEHYDROGENASE (AKR1C3)
UY37016A (en) INHIBITORS OF BRUTON TYROSINE KINASE AND METHODS OF USE
CL2013003056A1 (en) Compounds derived from (phenyl or pyridin) -ethynyl- (pyridin or pyrimidin) substituted; pharmaceutical composition comprising them; process of preparing this; and its use in the treatment of schizophrenia or cognitive diseases.
CR20170513A (en) USEFUL PIRAZOL DERIVATIVES AS INHIBITORS OF 5-LI-POXIGENASA ACTIVATING PROTEIN (FLAP).
DOP2019000221A (en) DERIVATIVES OF PIRAZOLE AS BROMODOMINIUM INHIBITORS
NI201500176A (en) PRODROG DERIVATIVES OF SUBSTITUTED TRIAZOLPYRIDINES
UY37444A (en) SUBSTITUTED DERIVATIVES OF 6- (1H-PIRAZOL-1-IL) PIRIMIDIN-4-AMINA AND ITS USE
CY1118552T1 (en) NEW Pyrimidine Derivatives as Phosphodiesterase Inhibitors 10 (PDE-10)
AR095353A1 (en) COMPOUND