CO6700886A2 - Imidazole derivatives as inhibitors of the enzyme pde10a - Google Patents
Imidazole derivatives as inhibitors of the enzyme pde10aInfo
- Publication number
- CO6700886A2 CO6700886A2 CO13129441A CO13129441A CO6700886A2 CO 6700886 A2 CO6700886 A2 CO 6700886A2 CO 13129441 A CO13129441 A CO 13129441A CO 13129441 A CO13129441 A CO 13129441A CO 6700886 A2 CO6700886 A2 CO 6700886A2
- Authority
- CO
- Colombia
- Prior art keywords
- provides
- subject
- compound
- formula
- effective amount
- Prior art date
Links
Abstract
Esta invención se refiere a compuestos (1) que son inhibidores de la enzima PDE1OA. La invención proporciona una composición farmacéutica que comprende una cantidad terapéuticamente eficaz de un compuesto de la invención y un portador farmacéuticamente aceptable. La presente invención proporciona asimismo procesos para usar en la preparación de los compuestos de fórmula I. La presente invención proporciona asimismo un método para tratar un sujeto que padece un trastorno neurodegenerativo que comprende administrar al sujeto una cantidad terapéuticamente eficaz de un compuesto de fórmula I. La presente invención proporciona asimismo un método para tratar a un sujeto que sufre de una adicción a sustancias, que comprende administrar al sujeto una cantidad terapéuticamente eficaz de un compuesto de fórmula I. La presente invención proporciona asimismo un método para tratar a un sujeto que padece un trastorno psiquiátrico, que comprende administrar al sujeto una cantidad terapéuticamente eficaz de un compuesto de fórmula I.This invention relates to compounds (1) that are inhibitors of the PDE1OA enzyme. The invention provides a pharmaceutical composition comprising a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier. The present invention also provides processes for use in the preparation of the compounds of formula I. The present invention also provides a method for treating a subject suffering from a neurodegenerative disorder comprising administering to the subject a therapeutically effective amount of a compound of formula I. The present invention also provides a method for treating a subject suffering from a substance addiction, which comprises administering to the subject a therapeutically effective amount of a compound of formula I. The present invention also provides a method for treating a subject suffering from a psychiatric disorder, which comprises administering to the subject a therapeutically effective amount of a compound of formula I.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US41535610P | 2010-11-19 | 2010-11-19 | |
| DKPA201001045 | 2010-11-19 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CO6700886A2 true CO6700886A2 (en) | 2013-06-28 |
Family
ID=48917333
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CO13129441A CO6700886A2 (en) | 2010-11-19 | 2013-05-27 | Imidazole derivatives as inhibitors of the enzyme pde10a |
Country Status (9)
| Country | Link |
|---|---|
| CL (1) | CL2013001397A1 (en) |
| CO (1) | CO6700886A2 (en) |
| DO (1) | DOP2013000108A (en) |
| HK (1) | HK1189593A1 (en) |
| HR (1) | HRP20150893T1 (en) |
| IL (1) | IL226344A (en) |
| MA (1) | MA34736B1 (en) |
| MX (1) | MX336915B (en) |
| SM (1) | SMT201500217B (en) |
-
2011
- 2011-11-18 MX MX2013005592A patent/MX336915B/en active IP Right Grant
-
2013
- 2013-05-13 IL IL226344A patent/IL226344A/en active IP Right Grant
- 2013-05-16 CL CL2013001397A patent/CL2013001397A1/en unknown
- 2013-05-16 DO DO2013000108A patent/DOP2013000108A/en unknown
- 2013-05-27 CO CO13129441A patent/CO6700886A2/en active IP Right Grant
- 2013-06-14 MA MA36011A patent/MA34736B1/en unknown
-
2014
- 2014-03-19 HK HK14102735.0A patent/HK1189593A1/en not_active IP Right Cessation
-
2015
- 2015-08-25 HR HRP20150893TT patent/HRP20150893T1/en unknown
- 2015-09-15 SM SM201500217T patent/SMT201500217B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IL226344A0 (en) | 2013-07-31 |
| DOP2013000108A (en) | 2013-09-30 |
| SMT201500217B (en) | 2015-10-30 |
| CL2013001397A1 (en) | 2013-08-30 |
| IL226344A (en) | 2016-08-31 |
| HK1189593A1 (en) | 2014-06-13 |
| MX336915B (en) | 2016-02-05 |
| MX2013005592A (en) | 2013-06-12 |
| MA34736B1 (en) | 2013-12-03 |
| HRP20150893T1 (en) | 2015-09-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Application granted |