CO6670570A2 - Pyrimidinated and condensed tirazins and their use - Google Patents

Pyrimidinated and condensed tirazins and their use

Info

Publication number
CO6670570A2
CO6670570A2 CO13003185A CO13003185A CO6670570A2 CO 6670570 A2 CO6670570 A2 CO 6670570A2 CO 13003185 A CO13003185 A CO 13003185A CO 13003185 A CO13003185 A CO 13003185A CO 6670570 A2 CO6670570 A2 CO 6670570A2
Authority
CO
Colombia
Prior art keywords
condensed
treatment
tirazins
pyrimidinated
prevention
Prior art date
Application number
CO13003185A
Other languages
Spanish (es)
Inventor
Markus Follmann
Johannes-Peter Stasch
Gorden Redlich
Jens Ackerstaff
Dormagen Griebenow
Andreas Knorr
Frank Wunder
Volkhart Li
Walter Kroh
Lars Barfacker
Original Assignee
Bayer Ip Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ip Gmbh filed Critical Bayer Ip Gmbh
Publication of CO6670570A2 publication Critical patent/CO6670570A2/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Cardiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Compuesto de la fórmula (I)La presente solicitud se refiere a pirimidinas y triazinas condensadas, a procesos para su preparación, a su uso solas o en combinaciones para el tratamiento y/o la prevención de enfermedades y a su uso para preparar medicamentos para el tratamiento y/o la prevención de enfermedades, en particular para el tratamiento y/o la prevención de trastornos cardiovasculares.Compound of the formula (I) The present application refers to condensed pyrimidines and triazines, processes for their preparation, their use alone or in combinations for the treatment and / or prevention of diseases and their use to prepare medicines for treatment and / or disease prevention, in particular for the treatment and / or prevention of cardiovascular disorders.

CO13003185A 2010-07-09 2013-01-09 Pyrimidinated and condensed tirazins and their use CO6670570A2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE102010031149A DE102010031149A1 (en) 2010-07-09 2010-07-09 New 1H-pyrazolo(3,4-b)pyridine compounds are guanylate cyclase stimulators useful to treat and/or prevent heart failure, angina pectoris, hypertonia, pulmonary hypertonia, ischemia, and vascular disease

Publications (1)

Publication Number Publication Date
CO6670570A2 true CO6670570A2 (en) 2013-05-15

Family

ID=45372624

Family Applications (1)

Application Number Title Priority Date Filing Date
CO13003185A CO6670570A2 (en) 2010-07-09 2013-01-09 Pyrimidinated and condensed tirazins and their use

Country Status (2)

Country Link
CO (1) CO6670570A2 (en)
DE (1) DE102010031149A1 (en)

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9314412D0 (en) 1993-07-13 1993-08-25 Rhone Poulenc Agriculture New compositions of matter
DE19642255A1 (en) 1996-10-14 1998-04-16 Bayer Ag Use of 1-benzyl-3- (substituted-hetaryl) fused pyrazole derivatives
DE19834044A1 (en) 1998-07-29 2000-02-03 Bayer Ag New substituted pyrazole derivatives
DE10220570A1 (en) 2002-05-08 2003-11-20 Bayer Ag Carbamate-substituted pyrazolopyridines
DE10317305B4 (en) 2003-04-14 2006-04-13 Carcoustics Tech Center Gmbh Cover for an aggregate in the engine compartment of a motor vehicle
EP1626045B1 (en) 2003-05-09 2010-09-08 Asahi Glass Company, Limited Processes for producing 3-substituted 2-chloro-5-fluoropyridine or salt thereof
JP4996257B2 (en) 2004-01-31 2012-08-08 アクチミス ファーマシューティカルズ インコーポレーテッド Imidazo [1,2-c] pyrimidinylacetic acid derivatives
US7541367B2 (en) 2005-05-31 2009-06-02 Janssen Pharmaceutica, N.V. 3-benzoimidazolyl-pyrazolopyridines useful in treating kinase disorders
TW200916468A (en) 2007-07-31 2009-04-16 Vertex Pharma Process for preparing 5-fluoro-1H-pyrazolo[3,4-b]pyridin-3-amine and derivatives thereof
US8741910B2 (en) 2008-11-25 2014-06-03 Merck Sharp & Dohme Corp. Soluble guanylate cyclase activators

Also Published As

Publication number Publication date
DE102010031149A1 (en) 2012-01-12

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Legal Events

Date Code Title Description
FG Application granted