CO6260103A2 - Composiciones que comprenden antigenos neumococidos - Google Patents

Composiciones que comprenden antigenos neumococidos

Info

Publication number
CO6260103A2
CO6260103A2 CO10023973A CO10023973A CO6260103A2 CO 6260103 A2 CO6260103 A2 CO 6260103A2 CO 10023973 A CO10023973 A CO 10023973A CO 10023973 A CO10023973 A CO 10023973A CO 6260103 A2 CO6260103 A2 CO 6260103A2
Authority
CO
Colombia
Prior art keywords
antigen
antigens
pneumococcal
polypeptides
combination
Prior art date
Application number
CO10023973A
Other languages
English (en)
Inventor
Claudio Donati
Alessandro Muzzi
Vega Masignani
Fabio Bagnoli
Paolo Ruggiero
Michele Barocchi
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of CO6260103A2 publication Critical patent/CO6260103A2/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
    • A61K39/092—Streptococcus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
    • A61K47/646—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent the entire peptide or protein drug conjugate elicits an immune response, e.g. conjugate vaccines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
    • C07K14/3156—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci from Streptococcus pneumoniae (Pneumococcus)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Biophysics (AREA)
  • Pulmonology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Mycology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicinal Preparation (AREA)

Abstract

La presente invención cree que una vacuna de Streptococcus pneumoniae efectiva puede requerir varios componentes antigénicos, y se han identificado varias combinaciones de polipéptidos neumocócicos para uso en inmunización. También pueden identificar algunos polipéptidos neumocócicos que pueden ser útiles como antígenos únicos. Estos polipéptidos pueden opcionalmente ser usados en combinación con sacáridos neumocócicos. Los antígenos se pueden usar en vacunas neumocócicas, pero también se pueden usar como componentes en vacunas para inmunizar nuevamente patógenos múltiples. 1.- Composición inmunogénica caracterizada porque comprende una combinación de antígenos S. pneumoníae, la combinación comprende dos o más antígenos seleccionados del grupo que consiste de: (1) antígeno spr0057; (2) antígeno spr0096; (3) antígeno spr0565; (4) antígeno spr2021; (5) antígeno spr1345; (6) antígeno spr1416; (7) antígeno spr1418; (8) antígeno spr0867; (9) antígeno spr1431; (10) antígeno spr1739; (11) antígeno spr1098; (12) antígeno spr0286; (13) antígeno spr1433; y/o (14) antígeno spr1707.
CO10023973A 2007-08-01 2010-03-01 Composiciones que comprenden antigenos neumococidos CO6260103A2 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0714963.6A GB0714963D0 (en) 2007-08-01 2007-08-01 Compositions comprising antigens
US96686607P 2007-08-29 2007-08-29

Publications (1)

Publication Number Publication Date
CO6260103A2 true CO6260103A2 (es) 2011-03-22

Family

ID=38529101

Family Applications (1)

Application Number Title Priority Date Filing Date
CO10023973A CO6260103A2 (es) 2007-08-01 2010-03-01 Composiciones que comprenden antigenos neumococidos

Country Status (20)

Country Link
US (2) US20110243976A1 (es)
EP (2) EP2197484A2 (es)
JP (2) JP2010535025A (es)
CN (2) CN104001165B (es)
AP (1) AP2010005173A0 (es)
AU (1) AU2008281438A1 (es)
BR (1) BRPI0813892A2 (es)
CA (1) CA2695169A1 (es)
CO (1) CO6260103A2 (es)
CY (1) CY1117689T1 (es)
DK (1) DK2572726T3 (es)
EA (1) EA018137B1 (es)
ES (1) ES2580957T3 (es)
GB (1) GB0714963D0 (es)
HR (1) HRP20160685T1 (es)
HU (1) HUE029670T2 (es)
PL (1) PL2572726T3 (es)
PT (1) PT2572726T (es)
SI (1) SI2572726T1 (es)
WO (1) WO2009016515A2 (es)

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