CO5271688A1 - Uso de inhibidor de secrecion de apoliproteinas b y/o de proteina de transferencia de trigliceridos microsmales - Google Patents
Uso de inhibidor de secrecion de apoliproteinas b y/o de proteina de transferencia de trigliceridos microsmalesInfo
- Publication number
- CO5271688A1 CO5271688A1 CO00083607A CO00083607A CO5271688A1 CO 5271688 A1 CO5271688 A1 CO 5271688A1 CO 00083607 A CO00083607 A CO 00083607A CO 00083607 A CO00083607 A CO 00083607A CO 5271688 A1 CO5271688 A1 CO 5271688A1
- Authority
- CO
- Colombia
- Prior art keywords
- transfer protein
- secretion inhibitor
- triglyceric
- microsomal
- apolipoprotein
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4468—Non condensed piperidines, e.g. piperocaine having a nitrogen directly attached in position 4, e.g. clebopride, fentanyl
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/472—Non-condensed isoquinolines, e.g. papaverine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
Abstract
El invento se relaciona con métodos y composiciones farmacéuticas útiles en reducir el consumo alimenticio en un animal, preferiblemente un mamífero incluyendo un sujeto humano o un animal de compañía, utilizando un inhibidor de la secreción de la apolipoproteína B/proteína de transferencia de triglicéricos microsomales. El invento preferiblemente se relaciona con métodos y composiciones farmacéuticas útiles en reducir el consumo alimenticio en un animal, preferiblemente un mamífero incluyendo un sujeto humano o un animal de compañía, utilizando un inhibidor de la secreción de la apolipoproteína B/proteína de transferencia de triglicéricos microsomales, y un agente antiobesidad. El invento además proporciona un kit el cual comprende una cantidad de un inhibidor de la secreción de la apolipoproteína B/proteína de transferencia de triglicéricos microsomales y un portador, vehículo o diluyente farmacéuticamente aceptable en una primera forma de dosificación unitaria; una cantidad de un agente anti-obesidad y un portador, vehículo o diluyente farmacéuticamente aceptable en una segunda forma de dosificación unitaria; y un recipiente.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US16451399P | 1999-11-10 | 1999-11-10 |
Publications (1)
Publication Number | Publication Date |
---|---|
CO5271688A1 true CO5271688A1 (es) | 2003-04-30 |
Family
ID=22594839
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CO00083607A CO5271688A1 (es) | 1999-11-10 | 2000-11-02 | Uso de inhibidor de secrecion de apoliproteinas b y/o de proteina de transferencia de trigliceridos microsmales |
Country Status (11)
Country | Link |
---|---|
EP (1) | EP1099438A3 (es) |
JP (1) | JP2001181209A (es) |
KR (1) | KR100439384B1 (es) |
AU (1) | AU777542B2 (es) |
CA (1) | CA2325282C (es) |
CO (1) | CO5271688A1 (es) |
HU (1) | HUP0004454A3 (es) |
IL (1) | IL139449A0 (es) |
NZ (1) | NZ508061A (es) |
PE (1) | PE20010679A1 (es) |
ZA (1) | ZA200006417B (es) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6825209B2 (en) | 2002-04-15 | 2004-11-30 | Research Triangle Institute | Compounds having unique CB1 receptor binding selectivity and methods for their production and use |
WO2005080373A1 (en) | 2004-02-04 | 2005-09-01 | Pfizer Products Inc. | Substituted quinoline compounds |
EP1890767A2 (en) * | 2005-05-27 | 2008-02-27 | Pfizer Products Inc. | Combination of a cannabinoid-1- receptor-antagonist and a microsomal triglyceride transfer protein inhibitor for treating obesity or mainataining weight loss |
WO2008090198A1 (en) * | 2007-01-25 | 2008-07-31 | Janssen Pharmaceutica Nv | Use of mtp inhibitors for increasing levels of satiety hormones |
EP3169343B1 (en) | 2014-07-15 | 2020-03-25 | Yissum Research and Development Company of the Hebrew University of Jerusalem Ltd. | Isolated polypeptides of cd44 and uses thereof |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1992018132A1 (en) * | 1991-04-17 | 1992-10-29 | Merck & Co., Inc. | Pharmaceutical combination for the treatment of benign prostatic hyperplasia comtaining a 5 alpha-reductase inhibitor |
US5474993A (en) * | 1994-06-14 | 1995-12-12 | Sterling Winthrop, Inc. | Lactam inhibitors of cholesterol esterase |
WO1996040640A1 (en) * | 1995-06-07 | 1996-12-19 | Pfizer Inc. | BIPHENYL-2-CARBOXYLIC ACID-TETRAHYDRO-ISOQUINOLIN-6-YL AMIDE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS INHIBITORS OF MICROSOMAL TRIGLYCERIDE TRANSFER PROTEIN AND/OR APOLIPOPROTEIN B (Apo B) SECRETION |
BR9709137A (pt) * | 1996-04-30 | 1999-08-03 | Pfizer | Processos e intermediários para a preparação de [2-(2H-[1,2,4]triazol-3-ilmetil)-1,2,3,4-tetra-hidro-isoquinolin-6-il]-amida do ácido 4'-trifluorometilbifenil-2-carboxílico |
US5883109A (en) * | 1996-07-24 | 1999-03-16 | Bristol-Myers Squibb Company | Method for lowering serum lipid levels employing an MTP inhibitor in combination with another cholesterol lowering drug |
AU716151B2 (en) * | 1996-11-27 | 2000-02-17 | Pfizer Inc. | Apo B-secretion/MTP inhibitory amides |
US5968950A (en) * | 1997-06-23 | 1999-10-19 | Pfizer Inc | Apo B-secretion/MTP inhibitor hydrochloride salt |
IL133201A0 (en) * | 1998-12-04 | 2001-03-19 | Pfizer Prod Inc | Lowering blood levels of lipoproten (a) |
-
2000
- 2000-11-02 CO CO00083607A patent/CO5271688A1/es not_active Application Discontinuation
- 2000-11-02 IL IL13944900A patent/IL139449A0/xx unknown
- 2000-11-03 EP EP00309705A patent/EP1099438A3/en not_active Withdrawn
- 2000-11-07 PE PE2000001184A patent/PE20010679A1/es not_active Application Discontinuation
- 2000-11-08 KR KR10-2000-0066044A patent/KR100439384B1/ko not_active IP Right Cessation
- 2000-11-08 CA CA002325282A patent/CA2325282C/en not_active Expired - Fee Related
- 2000-11-08 ZA ZA200006417A patent/ZA200006417B/xx unknown
- 2000-11-09 AU AU71519/00A patent/AU777542B2/en not_active Ceased
- 2000-11-09 HU HU0004454A patent/HUP0004454A3/hu unknown
- 2000-11-09 NZ NZ508061A patent/NZ508061A/en unknown
- 2000-11-10 JP JP2000344128A patent/JP2001181209A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
CA2325282C (en) | 2005-12-06 |
PE20010679A1 (es) | 2001-06-30 |
ZA200006417B (en) | 2002-05-08 |
IL139449A0 (en) | 2001-11-25 |
NZ508061A (en) | 2002-04-26 |
AU7151900A (en) | 2001-05-17 |
HU0004454D0 (es) | 2001-01-29 |
JP2001181209A (ja) | 2001-07-03 |
EP1099438A3 (en) | 2003-03-19 |
HUP0004454A3 (en) | 2004-04-28 |
KR100439384B1 (ko) | 2004-07-09 |
AU777542B2 (en) | 2004-10-21 |
CA2325282A1 (en) | 2001-05-10 |
KR20010051509A (ko) | 2001-06-25 |
HUP0004454A2 (hu) | 2001-10-28 |
EP1099438A2 (en) | 2001-05-16 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FC | Application refused |