CO2017010720A2 - Proceso para aislar y purificar ambrox - Google Patents

Proceso para aislar y purificar ambrox

Info

Publication number
CO2017010720A2
CO2017010720A2 CONC2017/0010720A CO2017010720A CO2017010720A2 CO 2017010720 A2 CO2017010720 A2 CO 2017010720A2 CO 2017010720 A CO2017010720 A CO 2017010720A CO 2017010720 A2 CO2017010720 A2 CO 2017010720A2
Authority
CO
Colombia
Prior art keywords
ambrox
purify
isolate
isolation
purification
Prior art date
Application number
CONC2017/0010720A
Other languages
English (en)
Inventor
Eric Eichhorn
Original Assignee
Givaudan Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Givaudan Sa filed Critical Givaudan Sa
Publication of CO2017010720A2 publication Critical patent/CO2017010720A2/es

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D9/00—Crystallisation
    • B01D9/005—Selection of auxiliary, e.g. for control of crystallisation nuclei, of crystal growth, of adherence to walls; Arrangements for introduction thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B57/00—Separation of optically-active compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B63/00—Purification; Separation; Stabilisation; Use of additives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/92—Naphthofurans; Hydrogenated naphthofurans
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11B—PRODUCING, e.g. BY PRESSING RAW MATERIALS OR BY EXTRACTION FROM WASTE MATERIALS, REFINING OR PRESERVING FATS, FATTY SUBSTANCES, e.g. LANOLIN, FATTY OILS OR WAXES; ESSENTIAL OILS; PERFUMES
    • C11B9/00—Essential oils; Perfumes
    • C11B9/0069—Heterocyclic compounds
    • C11B9/0073—Heterocyclic compounds containing only O or S as heteroatoms
    • C11B9/0076—Heterocyclic compounds containing only O or S as heteroatoms the hetero rings containing less than six atoms
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/02—Oxygen as only ring hetero atoms
    • C12P17/04—Oxygen as only ring hetero atoms containing a five-membered hetero ring, e.g. griseofulvin, vitamin C
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y504/00—Intramolecular transferases (5.4)
    • C12Y504/99—Intramolecular transferases (5.4) transferring other groups (5.4.99)
    • C12Y504/99017—Squalene--hopene cyclase (5.4.99.17)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/09—Geometrical isomers

Abstract

La presente invención se refiere a un método de aislamiento y purificación del ( ) Ambrox de una mezcla de reacción que comprende ( ) Ambrox y uno o más de los compuestos (II), (III) y (IV).
CONC2017/0010720A 2015-04-24 2017-10-20 Proceso para aislar y purificar ambrox CO2017010720A2 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB1507170.7A GB201507170D0 (en) 2015-04-24 2015-04-24 Process
PCT/EP2016/058997 WO2016170106A1 (en) 2015-04-24 2016-04-22 Process for isolating and purifying ambrox

Publications (1)

Publication Number Publication Date
CO2017010720A2 true CO2017010720A2 (es) 2018-01-31

Family

ID=53488739

Family Applications (1)

Application Number Title Priority Date Filing Date
CONC2017/0010720A CO2017010720A2 (es) 2015-04-24 2017-10-20 Proceso para aislar y purificar ambrox

Country Status (13)

Country Link
US (1) US10294211B2 (es)
EP (1) EP3286309B1 (es)
JP (3) JP7246133B2 (es)
CN (1) CN107548418B (es)
BR (1) BR112017021789B1 (es)
CO (1) CO2017010720A2 (es)
ES (1) ES2856887T3 (es)
GB (1) GB201507170D0 (es)
IL (1) IL254836B2 (es)
MX (1) MX2017013100A (es)
RU (1) RU2720094C2 (es)
SG (1) SG11201708085TA (es)
WO (1) WO2016170106A1 (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201507207D0 (en) 2015-04-24 2015-06-10 Givaudan Sa Enzymes and applications thereof
GB201618090D0 (en) 2016-10-26 2016-12-07 Givaudan Sa Product
BR112019015747A2 (pt) * 2017-02-24 2020-03-17 International Flavors & Fragrances Inc. Vetor recombinante, célula hospedeira recombinante, esqualeno hopeno ciclase recombinante, e, método para produção de ambroxano
EP3476822A1 (en) 2017-10-31 2019-05-01 Givaudan SA Process of making organic compounds
GB202011823D0 (en) 2020-07-30 2020-09-16 Givaudan Sa Method
GB202115120D0 (en) * 2021-10-21 2021-12-08 Givaudan Sa Organic compounds

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SU910561A1 (ru) * 1980-08-19 1982-03-07 Всесоюзный научно-исследовательский институт синтетических и натуральных душистых веществ Способ получени смеси душистых веществ дитерпеноидного р да
SU1498767A1 (ru) * 1987-06-04 1989-08-07 Институт Химии Ан Мсср Способ получени ( @ ) 3 @ ,6,6,9 @ -тетраметилпергидронафто [2,1-в]фурана
US5463089A (en) * 1994-07-22 1995-10-31 Quest International B.V. Preparation of ambrox
DE19524584A1 (de) * 1995-07-06 1997-01-09 Basf Ag Verfahren zur stereoselektiven Herstellung von (-)3a,6,6,9a-Tetramethyl-perhydronaphtho[2,1-b]furan
DE19649655A1 (de) 1996-11-29 1998-06-04 Haarmann & Reimer Gmbh Syntheseenzyme für die Herstellung von Coniferylalkohol, Coniferylaldehyd, Ferulasäure, Vanillin und Vanillinsäure und deren Verwendung
JP3207172B2 (ja) 1999-01-07 2001-09-10 科学技術振興事業団 光学活性環状化合物類の製造方法
DE19960106A1 (de) 1999-12-14 2001-06-21 Haarmann & Reimer Gmbh Enzyme und Gene für die Herstellung von Vanillin
US20040265850A1 (en) 2002-12-02 2004-12-30 Hua Wang Rapid detection of microorganisms
WO2004063699A2 (en) 2002-12-02 2004-07-29 The Ohio State University Research Foundation Rapid detection of microorganisms
CN100488940C (zh) * 2004-06-11 2009-05-20 湖南中烟工业有限责任公司 用于制备降龙涎醚或向卷烟烟气释放降龙涎醚的草酸酯及应用
EP1921130A4 (en) * 2005-08-04 2008-12-31 Shiseido Co Ltd PERFUME INGREDIENT SELECTION METHOD, FRAGMENT FORMULATION METHOD, AND TASTE PROMOTER
JP5236233B2 (ja) * 2007-09-04 2013-07-17 花王株式会社 （−）−アンブロキサンの製造方法
EP2438102B1 (de) 2009-06-05 2013-05-01 Basf Se Verbundteile enthaltend plastisch verformbaren polyurethanhartschaumstoff, klebstoff und abdeckmaterial
MX2011012757A (es) 2009-06-05 2011-12-16 Basf Se Produccion biocatalitica de ambroxan.
US8932839B2 (en) 2010-11-17 2015-01-13 Basf Se Method for the biocatalytic cyclization of terpenes and cyclase mutants employable therein
EP3470515B1 (de) 2010-11-17 2022-07-13 Basf Se Verfahren zur biokatalytischen cyclisierung von terpenen und darin einsetzbare cyclase-mutanten
JP2013132226A (ja) 2011-12-26 2013-07-08 Kao Corp （−）−３ａ，６，６，９ａ−テトラメチルドデカヒドロナフト［２，１−ｂ］フランの製造方法
US20130273619A1 (en) * 2012-04-16 2013-10-17 Basf Se Process for the Preparation of (3E, 7E)-Homofarnesol
CN104245647B (zh) * 2012-04-16 2017-06-09 巴斯夫欧洲公司 制备(3e,7e)‑高法呢醇的改进方法
US9902979B2 (en) 2013-09-05 2018-02-27 Niigata University Method for producing ambrein
GB201318886D0 (en) 2013-10-25 2013-12-11 Givaudan Sa Improvements i or relating to organic compounds
GB201318894D0 (en) 2013-10-25 2013-12-11 Givaudan Sa Improvements in or relating to organic compounds
GB201507207D0 (en) * 2015-04-24 2015-06-10 Givaudan Sa Enzymes and applications thereof
CN105037308B (zh) 2015-07-06 2017-06-06 四川中烟工业有限责任公司 一种制备降龙涎香醚的方法

Also Published As

Publication number Publication date
WO2016170106A1 (en) 2016-10-27
IL254836B1 (en) 2023-04-01
US20180134678A1 (en) 2018-05-17
JP2023093498A (ja) 2023-07-04
IL254836B2 (en) 2023-08-01
BR112017021789A2 (pt) 2018-07-31
EP3286309B1 (en) 2020-11-25
CN107548418A (zh) 2018-01-05
CN107548418B (zh) 2022-05-03
RU2017134436A (ru) 2019-05-24
JP2018513198A (ja) 2018-05-24
JP2021090423A (ja) 2021-06-17
SG11201708085TA (en) 2017-11-29
ES2856887T3 (es) 2021-09-28
US10294211B2 (en) 2019-05-21
RU2017134436A3 (es) 2019-10-09
IL254836A0 (en) 2017-12-31
GB201507170D0 (en) 2015-06-10
MX2017013100A (es) 2018-01-26
JP7246133B2 (ja) 2023-03-27
EP3286309A1 (en) 2018-02-28
RU2720094C2 (ru) 2020-04-24
BR112017021789B1 (pt) 2022-11-29
US20180346434A9 (en) 2018-12-06

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