CN2936273Y - Target control infusion pump and computer auxiliary infusion system using said infusion pump - Google Patents

Target control infusion pump and computer auxiliary infusion system using said infusion pump Download PDF

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Publication number
CN2936273Y
CN2936273Y CN 200620061690 CN200620061690U CN2936273Y CN 2936273 Y CN2936273 Y CN 2936273Y CN 200620061690 CN200620061690 CN 200620061690 CN 200620061690 U CN200620061690 U CN 200620061690U CN 2936273 Y CN2936273 Y CN 2936273Y
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China
Prior art keywords
module
syringe
hardware
software
mcu module
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Expired - Fee Related
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CN 200620061690
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Chinese (zh)
Inventor
瞿雪芬
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FUNIYA ELECTRONIC EQUIPMENT Co Ltd ZHUHAI
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FUNIYA ELECTRONIC EQUIPMENT Co Ltd ZHUHAI
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Priority to CN 200620061690 priority Critical patent/CN2936273Y/en
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Publication of CN2936273Y publication Critical patent/CN2936273Y/en
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Abstract

The utility model discloses a target controlled infusion pump, comprising a control unit, a mechanical unit and a syringe, wherein the control unit comprises a major MCU module of soft and hard wares as well as a programmable logic unit, a serial port communication module, an operating module and a display module which are connected with the major MCU soft and hard ware module; the mechanical unit comprises a stepping motor, a decelerator, a power transmission system and an injection propeller connected in order. The major MCU soft and hard ware module of the control unit can control the work of the mechanical unit through the programmable logic unit. The control unit also comprises a module to detect the syringe pressure, and the unit to detect the syringe pressure is also communicated with the major MCU soft and hard ware module. The unit to detect the syringe pressure can detect the pressure of the syringe pusher. The abnormal pressure is usually caused by malpractice of injection, and the pain to patients caused by malpractice can be effectively prevented. A secondary MCU module is also added to the utility model and can perform real-time supervision on the major MCU module so as to prevent mistakes caused by the major MCU module, thus improving the safety of clinical anesthesia and reducing risks.

Description

Target controlled infusion pump and utilize the area of computer aided infusion system of this infusion pump
Technical field
This utility model relates to automatic injection technique and computer-aided control field, relates in particular to a kind of target controlled infusion pump of the TCI of utilization technology and utilizes the area of computer aided infusion system of this infusion pump.
Background technology
In general, the normal injection pump comprises motor, deceleration device, power transmission and injecting propeller, and above-mentioned motor, deceleration device, power transmission and injecting propeller connect successively.The normal injection pump has only a kind of constant speed gasing injection function when clinical use.But human body is not uniformly, and medicine has complicated distribution, metabolism, effect process in human body, and common syringe pump can not be realized stable drug influence.
At above shortcoming, lot of domestic and international company utilizes target controlled infusion (Target controlledInfusion is called for short TCI) technology, develops the target controlled infusion pump that is more suitable for the human body infusion.The target controlled infusion of blood drug level, effect compartment concentration (TCI) technology is a kind of new medication pattern, can realize high-precision infusion function.Above-mentioned infusion pump has increased control unit, comprises MCU (microprogram control unit) module, operational module and display module, and operational module and display module are connected with the MCU module.The MCU module can be calculated the demand of human body to medicine automatically according to the parameter of human body, thus the flow of control medicine.
But pharmaceuticals industry is different and general industry, need bigger safety, because the MCU module is difficult to guarantee mess code whenever do not occur or enter endless loop, when other modules can not be discerned information in the MCU module, the infusion action will be destroyed, can patient's safety be made a big impact.Secondly, the target controlled infusion pump some maloperations occur easily when clinical use, and it is undesired to make syringe push away the pressure of handle.The syringe needle of such maloperation such as syringe has thrust muscle or other are not the places of blood vessel; Can bring pain to patient.Once more, current target controlled infusion pump can't be discerned the external diameter of syringe, can occur the coarse problem of infusion like this when system calculates the infusion of drug amount automatically unavoidably.
The utility model content
This utility model has overcome shortcoming of the prior art, and a kind of target controlled infusion pump of the TCI of utilization technology is provided.
In addition, this utility model also provides a kind of area of computer aided infusion system that utilizes above-mentioned target controlled infusion pump.
In order to solve the problems of the technologies described above, be achieved through the following technical solutions:
A kind of target controlled infusion pump, comprise control unit, machine assembly and syringe, control unit comprises main MCU module of software and hardware and the programmable logic device, serial communication module, operational module, the display module that link to each other with described main MCU module of software and hardware, machine assembly comprises motor, deceleration device, power transmission and the injecting propeller that connects successively, and the main MCU module of software and hardware of control unit is controlled the work of described machine assembly by programmable logic device; It is characterized in that described control unit also comprises the syringe pressure detection module, described syringe pressure checkout gear and the communication of main MCU module of software and hardware.
Whether as a kind of preferred version of the present utility model, described control unit also comprises the secondary MCU module of software and hardware that is connected by communication with main MCU module of software and hardware, normal in order to the work that detects main MCU module of software and hardware.
As a kind of preferred version of the present utility model, described syringe pressure detection module is connected with secondary MCU module of software and hardware, connects and the communication of main MCU module of software and hardware by secondary MCU module of software and hardware.
As a kind of preferred version of the present utility model, described syringe pressure detection module is a pressure transducer, and an end is connected with secondary MCU module of software and hardware, and the other end is connected with the handle that pushes away of syringe.
As a kind of preferred version of the present utility model, described control unit also comprises the syringe external diameter identification module that is connected with main MCU module of software and hardware, in order to the specification of identification syringe.
As a kind of preferred version of the present utility model, described control unit also comprises syringe external diameter identification module, in order to the specification of identification syringe, described syringe external diameter identification module is connected with secondary MCU module of software and hardware, by secondary MCU module of software and hardware and the communication of main MCU module of software and hardware.
As a kind of preferred version of the present utility model, described syringe is fixed with a pressing plate; Described syringe external diameter identification module is a pick off, and an end is connected with secondary MCU module of software and hardware, and the other end is connected with the fixing pressing plate of syringe.
As a kind of preferred version of the present utility model, described control unit also comprises the alarm module that links to each other with main MCU module of software and hardware.
A kind of area of computer aided infusion system that comprises above-mentioned target controlled infusion pump is characterized in that it also comprises PC, and described PC is by the serial communication module and the communication of target controlled infusion pump of described target controlled infusion pump.
As a kind of preferred version of the present utility model, described PC access network, the PC in this network all can with the communication of described target controlled infusion pump.
Compared with prior art, the control unit of this utility model target controlled infusion pump has increased secondary MCU module, and this module is the main MCU module of monitoring in real time, in case main MCU module is made mistakes, has improved the safety of clinical anesthesia, has reduced risk.The syringe pressure test section, this utility model can detect the pressure that syringe pushes away handle, normally because the maloperation in when injection, has thrust muscle as the syringe needle of syringe when pressure is undesired; Have corresponding warning if any maloperation and in time remind the medical worker, prevented that effectively maloperation from bringing patient's misery.In addition, the specification of syringe external diameter identification module injectable device, thus discerning its cross-sectional area, system can more accurate automatic calculating drug dose; The specification of syringe can show on display unit.
This utility model provides a kind of target controlled infusion pump of the TCI of utilization technology and utilizes the area of computer aided infusion system of this infusion pump, this system is except having high accuracy constant speed infusion function, can also utilize the high-speed computation ability of system, utilization colony medicine generation-pharmacodynamics model, real-time Simulation medicine distributed process in vivo, the target controlled infusion function of realization blood drug level, effect compartment concentration.The constant speed gasing injection function of this system is applicable to that clinical each section carries out the medicine chemotherapy of intravenous injection, anesthetis infusion, contrast agent and cancer patient.The target controlled infusion function is fit to anesthetis infusion, medical teaching and the medical research in each section or ICU (intensive care group) ward.Advantages such as it has that medication is various, drug model is complete, function of use is complete, simple to operate and safety height.This product both can unit substation formula be operated, again can be online the formula operation of main website of one-tenth system, both can the unit timing monitoring, can be unified into mode multimachine monitoring or the system management of system again with the anesthesia work station, so that hospital or the scientific research institution information gathering in the anesthesia process, network is integrated, Long-distance Control, case history inquiry.
Also increase alarm unit in the control module, can realize the warning of multiple thunder bolt.A) power supply power-fail warning function: when the alternating current power supply power down, the CAIS system buzzer warning is arranged and on display screen the display alarm content, press quiet key after chimes of doom stop; B) battery undervoltage warning function: when cell voltage be lower than running voltage (during 14.5V ± 0.2V), infusion system buzzer warning is arranged and on display screen the display alarm content, press quiet key after chimes of doom stop; C) push away sky/obstruction warning function: when syringe pushes away sky or blocks, system buzzer warning is arranged and on display screen the display alarm content, press quiet key after chimes of doom stop; D) the syringe warning function that comes off: when syringe comes off, system buzzer warning is arranged and on display screen the display alarm content, press quiet key after chimes of doom stop; E) medicine will be use up warning function: when the syringe medicine will be use up, system buzzer warning is arranged and on display screen the display alarm content, press quiet key after chimes of doom stop; F) the overload alarm function is set: when the drug level of artificial setting surpassed limited range, there was buzzer warning in system and display alarm content on display screen.
Description of drawings
Fig. 1 is a target controlled infusion pump structure sketch map;
Fig. 2 is a target controlled infusion pump structure block diagram;
Fig. 3 is the fundamental diagram of CAIS;
Fig. 4 is three Room pharmacokinetic model figure;
Fig. 5 is the operational flowchart of target controlled infusion pump.
The specific embodiment
Below in conjunction with drawings and Examples this utility model is elaborated.
See also Fig. 1 and Fig. 2, disclosed a kind of target controlled infusion pump among the figure, comprise control unit 1, machine assembly 2, syringe 3.Syringe 3 usefulness-pressing plate is fixed.
Control unit 1 comprises main MCU module of software and hardware 101, secondary MCU module of software and hardware 102, syringe pressure detection module 103, syringe external diameter identification module 104, reaches the serial communication module 105, combined-voltage detection module 106, operational module 107, data memory module 108, LCD (LCDs) display module 109, CPLD (CPLD is equipped with) module 110, the power amplifier module 111 that link to each other with described main MCU module of software and hardware; Syringe pressure detection module 103 is by secondary MCU module of software and hardware 202 and main MCU module of software and hardware 101 communications.
Machine assembly 2 comprises motor 201, deceleration device 202, power transmission 203 and the injecting propeller 204 that connects successively, main MCU module of software and hardware is by CPLD module 110 and power amplifier module 111 control step motors 201, and then the action of control machine assembly 2 each modules.
Wherein, the information parameter that main MCU module of software and hardware 101 obtains patients calculates injection speed, plasma calculated value, effective-site value of calculation and recovery time automatically, and with other module communications, coordinate each module work.Whether the work that secondary MCU module of software and hardware 202 is used for detecting main MCU module of software and hardware is normal, in case main MCU module of software and hardware 101 mess code occurs or enters endless loop; Simultaneously, because the single-chip microcomputer pin number in the main MCU module of software and hardware 101 is limited, in the present embodiment, syringe pressure detection module 103 and syringe external diameter identification module 104 insert the pin of secondary MCU module of software and hardware 202.Syringe pressure detection module 103 is a pressure transducer in the present embodiment, and this pressure transducer detects the pressure that syringe pushes away handle by the principle of active force and counteracting force.When detected pressure is excessive, can produce warning, operator are correspondingly processed.Syringe external diameter identification module 104 is similarly a pick off, and an end is connected with secondary MCU module of software and hardware 102, and the other end is connected with the fixing pressing plate of syringe; Syringe external diameter identification module 104 is used for discerning the specification of syringe external diameter.
This utility model also provides a kind of area of computer aided infusion system (CAIS) that utilizes above-mentioned target controlled infusion pump, and described area of computer aided infusion system also comprises PC, and PC is by the serial communication module 105 and the communication of target controlled infusion pump of target controlled infusion pump.Its effect is to be equivalent to anaesthetize work station, and this station not only can be made main website but also can do the substation, distributed process in the body of real-time Simulation medicine on work station.But the PC access network, by the authority setting, licensed user can utilize access to netwoks and control above-mentioned target controlled infusion pump.
The operation principle of CAIS:
See also Fig. 3, select infusion pattern (present embodiment has constant speed injection, the control of blood plasma target, three kinds of mode of operations of effect compartment target control) according to patient's clinical setting, system calculates the amount of inducing automatically and begins infusion after the input patient characteristics parameter; System at first with the certain dose of zero level pharmacokinetics speed infusion, makes it to be full of rapidly the central compartment between induction period, calculates metabolism and the amount of cancellation of medicine between chamber subsequently, and replenishes transhipment thing and metabolic medicine.According to pharmacokinetic parameter, system calculates patient's plasma concentration value, effective-site concentration and patient's recovery time automatically.
The anesthesia doctor can be according to patient's reaction and operation stimulus intensity regulated at will blood plasma aimed concn or effect compartment aimed concn value, when needs rising aimed concn, system calculates the medication amount that needs to replenish automatically and injects the central compartment, then stop infusion when reducing target level, decay to setting value until concentration.System calculates dwell time automatically and replenishes dose when stopping infusion and start shooting, make patient reach the aimed concn value very soon, keep the dynamic equilibrium of vivo medicine concentration,, can keep stable blood plasma or effect compartment concentration by this method so that reach best anaesthetic effect.
Pharmacology's framework of CAIS:
See also Fig. 4, Fig. 4 is three Room pharmacokinetic model figure.CAIS is the pharmacokinetics principle according to medicine, reduce the infusion velocity exponential damping of medicine gradually, what infusion scheme of the present utility model adopted is BET (loading, elimination and transhipment) scheme, injection speed, plasma calculated value, effective-site value of calculation recovery time calculate automatically by system, and the time of drawing in real time in the patient body-blood drug level trendgram.Concrete pharmacology's framework adopts open pharmacokinetics three-compartment model.
Intravenous anesthesia three-compartment model system: in linear pharmacokinetic model, medicine is transported to another chamber from a chamber speed is directly proportional with the dose of medicine in first chamber, and so-called linearity is because this scale factor is a constant constant (being that system can be unsaturated).For three following Room pharmacokinetic models, medicine equals the product of the dose speed constant K12 and the chamber 2 from chamber 1 (central compartment) to the transport velocity of chamber 2, medicine then is the product of the medication amount different speed constant K21 of another one and the chamber 2 from chamber 2 to the transport velocity of chamber 1, and medicine is the poor of preceding two products from chamber 1 to the net rate of chamber 2 transhipments.
The central compartment represents blood or blood plasma, and peripheral compartment 2 represents the many tissues of blood engorgement, and peripheral compartment 3 represents the few tissue of blood engorgement.K12, K21, K13, K31 are distribution rate constants between chamber, and this constant has been described the speed part that medicine exchanges in the unit interval between chamber.K10 is the elimination rate constant from the central compartment.Effect is imaginary effect compartment, imaginary effect compartment volume is 1/1000 of central compartment in the general pharmacokinetic model, the effect compartment medicine is eliminated does not influence central compartment's drug concentrations variation, the speed constant of medicine entrance effect chamber, central compartment is Kle, and the speed constant that medicine is eliminated from effect compartment is ke0.Above-mentioned constant K 12, K21, K13, K31, K10, Kle and ke0 are determined by system automatically according to patient's data message.
The workflow of target controlled infusion pump:
See also Fig. 5, target controlled infusion pump of the present utility model comprises following process when work:
(1) operator open the power supply of target controlled infusion pump, and the control unit initialization parameters of target controlled infusion pump detects whether operate as normal of each module simultaneously;
(2) operator import the target controlled infusion pump to data message by the keyboard of above-mentioned infusion pump, or the PC input by being connected with above-mentioned infusion pump, perhaps directly read patient's related data information from the data base of patient information; Above-mentioned data message comprises patient's the data message (as sex, age, body weight, the state of an illness) or the infusion concentration and the speed of medicine;
(3) main MCU module of software and hardware 101 is analyzed above-mentioned key entries or the data that read are analyzed from the data base of patient information, judges whether infusion;
(4) main MCU module of software and hardware 101 is judged the concrete medication amount of infusion and infusion in which way according to the described parameter of process (4);
(5) when going wrong, judgement is the problem that the medicine reason that is about to use up or syringe push away sky or obstruction;
(6) if the reason that medicine is used up, alarm unit produces medicine and will report to the police to the greatest extent;
(7) if syringe pushes away the problem of sky or obstruction, main MCU module of software and hardware 101 sends the information that stops infusion, and alarm unit produces and pushes away sky/obstruction warning;
(8) operator do corresponding processing according to different alarm signals.
Above embodiment is the unrestricted the technical solution of the utility model in order to explanation only.As, control unit does not have secondary MCU module of software and hardware, and adopts syringe pressure detection module and syringe external diameter identification module directly to be connected with main MCU module of software and hardware.Any modification or partial replacement that does not break away from this utility model spirit and scope all should be encompassed in the middle of the claim scope of the present utility model.

Claims (10)

1, a kind of target controlled infusion pump, comprise control unit, machine assembly and syringe, control unit comprises main MCU module of software and hardware and the programmable logic device, serial communication module, operational module, the display module that link to each other with described main MCU module of software and hardware, machine assembly comprises motor, deceleration device, power transmission and the injecting propeller that connects successively, and the main MCU module of software and hardware of control unit is controlled the work of described machine assembly by programmable logic device; It is characterized in that described control unit also comprises the syringe pressure detection module, described syringe pressure checkout gear and the communication of main MCU module of software and hardware.
Whether 2, target controlled infusion pump according to claim 1 is characterized in that, described control unit also comprises the secondary MCU module of software and hardware that is connected by communication with main MCU module of software and hardware, normal in order to the work that detects main MCU module of software and hardware.
3, target controlled infusion pump according to claim 2 is characterized in that, described syringe pressure detection module is connected with secondary MCU module of software and hardware, connects and the communication of main MCU module of software and hardware by secondary MCU module of software and hardware.
4, target controlled infusion pump according to claim 3 is characterized in that, described syringe pressure detection module is a pressure transducer, and an end is connected with secondary MCU module of software and hardware, and the other end is connected with the handle that pushes away of syringe.
According to claim 1 or 2 or 3 or 4 described target controlled infusion pumps, it is characterized in that 5, described control unit also comprises the syringe external diameter identification module that is connected with main MCU module of software and hardware, in order to the specification of identification syringe.
6, according to claim 1 or 2 or 3 or 4 described target controlled infusion pumps, it is characterized in that, described control unit also comprises syringe external diameter identification module, specification in order to the identification syringe, described syringe external diameter identification module is connected with secondary MCU module of software and hardware, by secondary MCU module of software and hardware and the communication of main MCU module of software and hardware.
7, target controlled infusion pump according to claim 6 is characterized in that, described syringe is fixed with a pressing plate; Described syringe external diameter identification module is a pick off, and an end is connected with secondary MCU module of software and hardware, and the other end is connected with the fixing pressing plate of syringe.
8, according to claim 1 or 2 or 3 or 4 described target controlled infusion pumps, it is characterized in that described control unit also comprises the alarm module that links to each other with main MCU module of software and hardware.
9, a kind of area of computer aided infusion system that comprises any described target controlled infusion pump of claim 1 to 4 is characterized in that it also comprises PC, and described PC is by the serial communication module and the communication of target controlled infusion pump of described target controlled infusion pump.
10, area of computer aided infusion system according to claim 9 is characterized in that, described PC access network, the PC in this network all can with the communication of described target controlled infusion pump.
CN 200620061690 2006-07-17 2006-07-17 Target control infusion pump and computer auxiliary infusion system using said infusion pump Expired - Fee Related CN2936273Y (en)

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104739520A (en) * 2015-04-20 2015-07-01 匡仁锐 Control method of medical filling pump and system using method
CN112957567A (en) * 2021-02-09 2021-06-15 杭州堃博生物科技有限公司 Injection pump control method, system and equipment thereof
CN112971973A (en) * 2021-02-09 2021-06-18 杭州堃博生物科技有限公司 Push handle torque adjusting device and method of injector and injection pump

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104739520A (en) * 2015-04-20 2015-07-01 匡仁锐 Control method of medical filling pump and system using method
CN112957567A (en) * 2021-02-09 2021-06-15 杭州堃博生物科技有限公司 Injection pump control method, system and equipment thereof
CN112971973A (en) * 2021-02-09 2021-06-18 杭州堃博生物科技有限公司 Push handle torque adjusting device and method of injector and injection pump

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GR01 Patent grant
C17 Cessation of patent right
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20070822

Termination date: 20110717