CN2803309Y - Dynamic, static and washing three-in-one full automatic toxicity inhalation testing device - Google Patents
Dynamic, static and washing three-in-one full automatic toxicity inhalation testing device Download PDFInfo
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- CN2803309Y CN2803309Y CN 200520026707 CN200520026707U CN2803309Y CN 2803309 Y CN2803309 Y CN 2803309Y CN 200520026707 CN200520026707 CN 200520026707 CN 200520026707 U CN200520026707 U CN 200520026707U CN 2803309 Y CN2803309 Y CN 2803309Y
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Abstract
The utility model provides a dynamic, static and washing three in one full automatic toxicity inhalation experimental device, which comprises a dynamic poisoning control instrument of a microcomputer control device, a high pressure two-phase flow atomizer, a preblending gravity separating can and an animal cabin, wherein the dynamic poisoning control instrument of the microcomputer control device is orderly connected with the high pressure two-phase flow atomizer and the preblending gravity separating can through a liquid phase pipeline, a gas phase pipeline and a liquid recovery device, then the dynamic poisoning control instrument of the microcomputer control device is connected with the animal cabin through an inlet blending gas pipeline, and the top part of the animal cabin is provided with an end cap, which replaces a plurality of poisoning exchange caps through the unlocking of a rapid padlock. The utility model has the effects that the utility model integrates three functions of dynamic poisoning, static poisoning and washing of the full automatic toxicity inhalation experimental device into the same apparatus, and completes three functions at the same time, which saves cost, reduces occupying space, facilitates operation and relieves pollution of operating staff. The device is formed by that the toxic smog particles of the animal cabin are just tiny particles which are suitable for an animal to inhale into the alveoli of the animal, and by adopting a rotating platform, the breathing concentration of each animal is equal, which results in better poisoning effect.
Description
Technical field
This utility model relates to a kind of dynamic formula, quiet formula, cleans three-in-one full-automatic toxicity on inhalation experimental provision.
Background technology
General exposure experiment has dynamic formula contamination and exposure in static total enclosure chamber, and the various dynamic contamination devices in past mainly are applicable to the dynamic suction-type exposure experiment of animal for water solublity or oil-soluble xenobiotics, and this tests only suitable dynamic formula exposure experiment.It produces the aerosol particles size and all is distributed in the animal storehouse, and it is the bulky grain aerosol that can not be drawn into the animal alveolar that the overwhelming majority is arranged, and causes contamination efficient low, inaccurate.Because animal is placed on the phenomenon that flocks together when contaminating in the same cage, cause the concentration difference, and each side's site concentration also has difference in the animal storehouse.Dynamic formula contamination and exposure in static total enclosure chamber must carry out respectively with two complete equipments, and it is big to take up room like this, and the expense height, and operation is also inconvenient.In addition, above-mentioned dynamic formula contamination and exposure in static total enclosure chamber do not have the function of automatic cleaning.
Summary of the invention
For solving the problem that exists in the above-mentioned technology, the purpose of this utility model provides a kind of dynamic formula, quiet formula, cleans three-in-one full-automatic toxicity on inhalation experimental provision, to be implemented in three kinds of functions finishing exposure experiment on the same equipment, saved expense simultaneously, minimizing takes up room, handled easily has also been exempted the pollution to operator, has improved the safety of operation.
For achieving the above object, the technical solution adopted in the utility model provides a kind of dynamic formula, quiet formula, clean three-in-one full-automatic toxicity on inhalation experimental provision, wherein: this device includes the dynamic formula contamination controller that is provided with computer control device, high pressure two-phase flow nebulizer, give the mixing gravity separator tank, the animal storehouse, the described dynamic formula contamination controller that is provided with computer control device is connected described high pressure two-phase flow nebulizer successively and gives the mixing gravity separator tank by liquid phase pipeline and gas phase pipeline, be connected with described animal storehouse again by input mixing air pipe then, the end cap of changing a plurality of contamination transposing lids by the unlatching of quick padlock is set at the top in described animal storehouse.
Exposure in static total enclosure chamber transposing lid when the dynamic formula contamination transposing lid the when end cap that a plurality of contaminations transposing lid is changed in described unlatching by quick padlock is dynamic contamination, static contamination and the animal storehouse flushing transposing lid when cleaning.
Described liquid withdrawal system is located at described bottom of giving the mixing gravity separator tank, and is connected with high pressure two-phase flow nebulizer.
Be provided with rotation animal platform in the described animal storehouse, on described rotation animal platform, be provided with a plurality of cage for animals by driven by motor.
Be respectively equipped with switch valve on the top and the bottom of described animal storehouse one side.
The bottom of described animal storehouse one side is provided with gas exhaust piping and the waste gas purification apparatus that is connected successively with described switch valve.
Effect of the present utility model is with dynamic formula contamination, the exposure in static total enclosure chamber of full-automatic toxicity on inhalation experimental provision and cleans three-in-one on same equipment, replacing by three kinds of different upper end covers, while opening and closing of fault air inlet-outlet pipe, three kinds of functions are concentrated on the same tank body, and by the control of dynamic formula contamination control generating means, reach the purpose of dynamic formula, quiet formula, the three-in-one toxicity on inhalation experimental provision of cleaning, filled up the defective that to carry out dynamic experiment in the experiment in the past.Finish three kinds of functions simultaneously on an equipment, saved expense, minimizing takes up room, and handled easily has also been exempted the pollution to operator.And pre-mixing Gravity Separation technology to make the malicious mist granule that arrives in the animal storehouse just in time be to be fit to animal to be drawn into IA molecule, the breathing concentration that the employing rotation platform makes each animal is average homogeneity all the time, makes the contamination better effects if.
Description of drawings
Fig. 1 is a structural representation of the present utility model.
Among the figure:
1, dynamic formula contamination controller 2, liquid phase pipeline
3, gas phase pipeline 4, high pressure two-phase flow nebulizer
5, give mixing gravity separator tank 6, exposure in static total enclosure chamber transposing lid
7, input mixing air pipe 8, gas sampling mouth
9, waste gas purification apparatus 10, gas exhaust piping
11, switch valve 12, quick padlock
13, dynamic formula contamination transposing cover 14, the animal storehouse
15, cage for animal 16, rotation animal platform
17, driving motor 18, discharge of wastewater valve
19, the flushing transposing of animal storehouse cover 20, liquid withdrawal system
The specific embodiment
Reaching embodiment in conjunction with the accompanying drawings is illustrated dynamic formula of the present utility model, quiet formula, the three-in-one full-automatic toxicity on inhalation experimental provision of cleaning.
Dynamic formula of the present utility model, quiet formula, the structure of cleaning three-in-one full-automatic toxicity on inhalation experimental provision is to include the dynamic formula contamination controller 1 that is provided with computer control device, high pressure two-phase flow nebulizer 4, give mixing gravity separator tank 5, animal storehouse 14, the described dynamic formula contamination controller 1 that is provided with computer control device is connected described high pressure two-phase flow nebulizer 4 successively and gives mixing gravity separator tank 5 with gas phase pipeline 3 and liquid withdrawal system 20 by liquid phase pipeline 2, be connected with described animal storehouse 14 again by input mixing air pipe 7 then, be provided with the rotation animal platform 16 that drives by motor 17 in the described animal storehouse 14, on described rotation animal platform 16, be provided with a plurality of cage for animals 15.At the end cap of the top in described animal storehouse 14 setting by a plurality of contaminations transposing of the replacing of the unlatching of quick padlock 12 lid, when dynamic contamination, the end cap at 14 tops, animal storehouse is that dynamic formula contamination transposing covers 13; When static state is contaminated, quick padlock 12 to be opened, the dynamic formula contamination transposing of removing 14 tops, animal storehouse covers 13, and the exposure in static total enclosure chamber transposing that changes into covers 6; When cleaning, will change and cover 13 or 6 and remove, change the animal storehouse into and wash to change and cover 19.
Be respectively equipped with switch valve 11 on the top and the bottom of described animal storehouse 14 1 sides, simultaneously, the bottom of described animal storehouse 14 1 sides also is provided with gas exhaust piping 10 and the waste gas purification apparatus 9 that is connected successively with described switch valve 11.
High pressure two-phase flow nebulizer 4 in this experimental provision adopts high pressure two-phase flow spraying technique and aerojet to mix, and the concentration of contamination is fully adjustable, so gas concentration can satisfy different contamination requirements to saturated mode from zero, and can guarantee continual and steady air feed.In whole contamination process, medicine can be evenly distributed on each orientation in the animal storehouse 14, because this device has used pre-mixing gravity separator tank 5, can be with the aerosol that begins to take shape mix homogeneously therein, the atomization gas that filters out the molecule that helps the toxicity on inhalation experiment most is transported in the zoopery storehouse, and the atomization gas of larger particles, separate by the terrestrial gravitation gravity principle, after making it be reduced into liquid state, under the effect of dynamic formula contamination controller 1, liquid after will reducing from pre-mixing knockout drum 5 is drawn in the liquid withdrawal system 20, carries out recycling.So resulting medicine mistiness degree is effectively to suck concentration of contamination fully in animal storehouse 14, can make the concentration of experiment satisfy the experiment of multiple requirement to greatest extent.
Rotatable mobile animal platform 16 in this experimental provision, when the toxicity on inhalation experiment is carried out, for guaranteeing that all animal subjects have identical suction volume and tried concentration, this device has adopted animal platform rotation technique, adopt microcomputer control by a motor 17, to test needed parameters and requirement gives in the first loading routine, add the wind speed adjusting of temperature, gas and the time of experiment etc. as giving of sample, and have the function of indexs such as real-time monitoring temperature, humidity, time, pressure and flow.Because liquid solidifies at low temperatures easily, therefore earlier liquid after the heating, is flowed into nebulizer 4 again in contamination controller 1, can finish dynamic formula and the experimental work of quiet formula toxicity on inhalation so accurately, easily.
The dynamic formula contamination.
When being used as the dynamic formula exposure experiment, as shown in Figure 1, set the dynamic formula contamination controller 1 that is provided with computer control device earlier, by in the dynamic formula contamination controller 1 clean gas and toxic liquid being flowed into high pressure two-phase flow nebulizer 4 simultaneously from liquid phase pipeline 2 and gas phase pipeline 3, give mixing gravity separator tank 5 by in the high pressure two-phase flow nebulizer 4 liquids and gases being mixed the back inflow again, pre-mixing knockout drum 5 becomes the toxic gas that is suitable for the molecule that animal sucks most with gas and the abundant mixing of liquid and flows into into input mixing air pipe 7, pass through liquid withdrawal system 20 recyclings after the residue bulky grain atomization gas liquefy, poison enters in the animal storehouse 14 from mixing air pipe 7, directly enter in the cage for animal 15, animal subject rotates in the lump by driving motor 17 driven rotary animal platforms 16, makes animal subject accept contamination uniformly in rotation.In the contamination process, can from the gas sampling mouth 8 that is located at animal storehouse 14 1 sides, take out a small amount of gas and chemically examine, poison, is discharged directly from gas exhaust piping 10 inflow exhaust gas purifiers 9 at last by behind the cage for animal 15.At this moment, the end cap at 14 tops, animal storehouse is that dynamic formula contamination transposing covers 13.
Exposure in static total enclosure chamber.
When being used as the exposure in static total enclosure chamber experiment, as shown in Figure 1, quick padlock 12 is opened, remove dynamic formula contamination transposing and cover 13, change the exposure in static total enclosure chamber transposing into and cover 6, be closed in two switch valves 11 that are respectively equipped with on the top and the bottom of animal storehouse 14 1 sides simultaneously, just form the exposure in static total enclosure chamber device, carry out the exposure in static total enclosure chamber experiment easily.
Clean.
When cleaning, as shown in Figure 1, with dynamic formula contamination transposing cover 13 or exposure in static total enclosure chamber change and cover 6 and remove, change the 14 flushing transposings of animal storehouse into and cover 19, connect water purification 14 inside, animal storehouse are washed comprehensively, flushing finishes, open discharge of wastewater valve 18, waste water is discharged, finish cleaning.
Claims (6)
1, a kind of dynamic formula, quiet formula, clean three-in-one full-automatic toxicity on inhalation experimental provision, it is characterized in that: this device includes the dynamic formula contamination controller (1) that is provided with computer control device, high pressure two-phase flow nebulizer (4), give mixing gravity separator tank (5), animal storehouse (14), the described dynamic formula contamination controller (1) that is provided with computer control device is connected described high pressure two-phase flow nebulizer (4) successively and gives mixing gravity separator tank (5) with gas phase pipeline (3) and liquid withdrawal system (20) by liquid phase pipeline (2), be connected with described animal storehouse (14) again by input mixing air pipe (7) then, the end cap of changing a plurality of contamination transposing lids by the unlatching of quick padlock (12) is set at the top in described animal storehouse (14).
2, dynamic formula according to claim 1, quiet formula, clean three-in-one full-automatic toxicity on inhalation experimental provision, it is characterized in that: exposure in static total enclosure chamber transposing lid (6) when the dynamic formula contamination transposing lid (13) the when end cap that a plurality of contaminations transposing lids are changed in described unlatching by quick padlock (12) is dynamic contamination, static contamination and the moving full-automatic toxicity on inhalation exposure experimental device storehouse flushing when cleaning are changed and are covered (19).
3, dynamic formula according to claim 1, quiet formula, the three-in-one full-automatic toxicity on inhalation experimental provision of cleaning, it is characterized in that: described liquid withdrawal system (20) is located at described bottom of giving mixing gravity separator tank (5), and is connected with high pressure two-phase flow nebulizer (4).
4, dynamic formula according to claim 1, quiet formula, the three-in-one full-automatic toxicity on inhalation experimental provision of cleaning, it is characterized in that: be provided with the rotation animal platform (16) that drives by motor (17) in the described animal storehouse (14), on described rotation animal platform (16), be provided with a plurality of cage for animals (15).
5, dynamic formula according to claim 1, quiet formula, the three-in-one full-automatic toxicity on inhalation experimental provision of cleaning is characterized in that: be respectively equipped with switch valve (11) on the top and the bottom of described animal storehouse (14) one sides.
6, according to claim 1 or 4 described dynamic formulas, quiet formula, clean three-in-one full-automatic toxicity on inhalation experimental provision, it is characterized in that: the bottom of described animal storehouse (14) one sides is provided with gas exhaust piping (10) and the waste gas purification apparatus (9) that is connected successively with described switch valve (11).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200520026707 CN2803309Y (en) | 2005-07-19 | 2005-07-19 | Dynamic, static and washing three-in-one full automatic toxicity inhalation testing device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200520026707 CN2803309Y (en) | 2005-07-19 | 2005-07-19 | Dynamic, static and washing three-in-one full automatic toxicity inhalation testing device |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN2803309Y true CN2803309Y (en) | 2006-08-09 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 200520026707 Expired - Lifetime CN2803309Y (en) | 2005-07-19 | 2005-07-19 | Dynamic, static and washing three-in-one full automatic toxicity inhalation testing device |
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|---|---|
| CN (1) | CN2803309Y (en) |
Cited By (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100464721C (en) * | 2007-08-15 | 2009-03-04 | 庞宝森 | Passive smoking flue toxicity contaminated box |
| CN102138832A (en) * | 2011-03-25 | 2011-08-03 | 天津开发区合普工贸有限公司 | Niton exposure poisoning experimental equipment |
| CN102172336A (en) * | 2011-03-11 | 2011-09-07 | 山西农业大学 | Simple dynamic sulfur dioxide gas toxicant exposure experimental device |
| CN102380433A (en) * | 2011-07-26 | 2012-03-21 | 天津开发区合普工贸有限公司 | Anti-explosion solid-phase dust contamination equipment |
| CN102641156A (en) * | 2012-05-03 | 2012-08-22 | 天津开发区合普工贸有限公司 | Anti-explosion safe shielding device for gas contamination cabinet |
| CN102670328A (en) * | 2012-05-29 | 2012-09-19 | 天津开发区合普工贸有限公司 | Pathogenic bacteria inhalation toxicology experimental equipment for respiratory system |
| CN102935018A (en) * | 2012-11-13 | 2013-02-20 | 天津开发区合普工贸有限公司 | Animal experiment device for passive smoke produced by human smoking |
| CN103385769A (en) * | 2013-08-19 | 2013-11-13 | 天津开发区合普工贸有限公司 | Integrated sectioning cavity multi-concentration gas contamination device |
| CN104116573A (en) * | 2014-08-06 | 2014-10-29 | 南通大学 | Up-and-down type filtered CO poisoning device |
| CN104367398A (en) * | 2013-08-13 | 2015-02-25 | 北京慧荣和科技有限公司 | Whole body exposure system for animals |
| CN104367395A (en) * | 2013-08-13 | 2015-02-25 | 北京慧荣和科技有限公司 | Whole body exposure chamber for animals |
-
2005
- 2005-07-19 CN CN 200520026707 patent/CN2803309Y/en not_active Expired - Lifetime
Cited By (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100464721C (en) * | 2007-08-15 | 2009-03-04 | 庞宝森 | Passive smoking flue toxicity contaminated box |
| CN102172336A (en) * | 2011-03-11 | 2011-09-07 | 山西农业大学 | Simple dynamic sulfur dioxide gas toxicant exposure experimental device |
| CN102138832A (en) * | 2011-03-25 | 2011-08-03 | 天津开发区合普工贸有限公司 | Niton exposure poisoning experimental equipment |
| CN102380433A (en) * | 2011-07-26 | 2012-03-21 | 天津开发区合普工贸有限公司 | Anti-explosion solid-phase dust contamination equipment |
| CN102380433B (en) * | 2011-07-26 | 2014-03-05 | 天津开发区合普工贸有限公司 | Anti-explosion solid-phase dust contamination equipment |
| CN102641156A (en) * | 2012-05-03 | 2012-08-22 | 天津开发区合普工贸有限公司 | Anti-explosion safe shielding device for gas contamination cabinet |
| CN102641156B (en) * | 2012-05-03 | 2013-10-09 | 天津开发区合普工贸有限公司 | Anti-explosion safe shielding device for gas contamination cabinet |
| CN102670328A (en) * | 2012-05-29 | 2012-09-19 | 天津开发区合普工贸有限公司 | Pathogenic bacteria inhalation toxicology experimental equipment for respiratory system |
| CN102670328B (en) * | 2012-05-29 | 2015-03-25 | 天津开发区合普工贸有限公司 | Pathogenic bacteria inhalation toxicology experimental equipment for respiratory system |
| CN102935018B (en) * | 2012-11-13 | 2014-11-26 | 天津开发区合普工贸有限公司 | Animal experiment device for passive smoke produced by human smoking |
| CN102935018A (en) * | 2012-11-13 | 2013-02-20 | 天津开发区合普工贸有限公司 | Animal experiment device for passive smoke produced by human smoking |
| CN104367398A (en) * | 2013-08-13 | 2015-02-25 | 北京慧荣和科技有限公司 | Whole body exposure system for animals |
| CN104367395A (en) * | 2013-08-13 | 2015-02-25 | 北京慧荣和科技有限公司 | Whole body exposure chamber for animals |
| CN103385769A (en) * | 2013-08-19 | 2013-11-13 | 天津开发区合普工贸有限公司 | Integrated sectioning cavity multi-concentration gas contamination device |
| CN103385769B (en) * | 2013-08-19 | 2015-03-25 | 天津开发区合普工贸有限公司 | Integrated sectioning cavity multi-concentration gas contamination device |
| CN104116573A (en) * | 2014-08-06 | 2014-10-29 | 南通大学 | Up-and-down type filtered CO poisoning device |
| CN104116573B (en) * | 2014-08-06 | 2015-06-10 | 南通大学 | Up-and-down type filtered CO poisoning device |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| EE01 | Entry into force of recordation of patent licensing contract |
Assignee: Tianjin Development Zone Hepu Industry and Trade Co., Ltd. Assignor: Fan Weilin Contract fulfillment period: 2008.12.31 to 2014.12.31 Contract record no.: 2009120000156 Denomination of utility model: Dynamic, static and washing three-in-one full automatic toxicity inhalation testing device Granted publication date: 20060809 License type: Exclusive license Record date: 20090731 |
|
| LIC | Patent licence contract for exploitation submitted for record |
Free format text: EXCLUSIVE LICENSE; TIME LIMIT OF IMPLEMENTING CONTACT: 2008.12.31 TO 2014.12.31; CHANGE OF CONTRACT Name of requester: TIANJIN DEVELOPMENT ZONE HOPE INDUSTRIAL AND TRADI Effective date: 20090731 |
|
| CX01 | Expiry of patent term |
Expiration termination date: 20150719 Granted publication date: 20060809 |
|
| EXPY | Termination of patent right or utility model |