CN2612353Y

CN2612353Y - Biodegradable cervical vertebra inosculation device

Info

Publication number: CN2612353Y
Application number: CNU032368437U
Authority: CN
Inventors: 吴广森; 靳安民
Original assignee: ZHUJIANG HOSPITAL NO 1 MILITAR
Current assignee: ZHUJIANG HOSPITAL NO 1 MILITAR; Southern Medical University
Priority date: 2003-01-28
Filing date: 2003-01-28
Publication date: 2004-04-21
Anticipated expiration: 2013-01-28

Abstract

A bioactivity degradable cervical intervertebral fusion cage belongs to medical apparatus accessory field. A cylinder is formed into high polymer material, and is characterized in that the configuration is the wedge cylinder whereof upper and lower round end faces are not equal. The surface of the cylinder is cut with thread. The bottom round end face is opened with a groove which is engaged with a screwdriver. A cross-through tunnel is opened in the wedge cylinder. The utility model provides a cervical intervertebral fusion cage which has high-intensity, low modulus, good bioavailability, bone-forming induction and conducting function, and is degradable finally in the body.

Description

The biological degradable cervical fusion cage

Technical field

This utility model belongs to the fitting of medical apparatus field, specially refers to a kind of biological degradable cervical fusion cage.

Background technology

Human body because of between disc degradation, vertebral tumor excision and wound postcentrum fracture dislocation, the cervical stability forfeiture that bony defect etc. cause, the healthy of people in serious harm, the intervertebral disc of excision regression, it is the method for optimizing of this problem of liberation that interbody bone graft merges, the multiple transplantation substitute integrating materials of using clinically exists obvious defects and deficiency at present, transplanting can cause for bone district's chronic pain and partial sensory disturbance as autologous ilium, homogeneous allogenic bone transplantation can cause the danger of immunity eliminating reaction and pathophoresis, metal rack then elastic modelling quantity is big, biocompatibility difference and electrolytic etching, foreign body stimulation etc., the someone studies carbon fibre reinforcement in recent years, materials such as synthetic polyester, all can not produce little effect by induced osteogenesis again because of neither degrading, people begin to turn to the applied research of macromolecule polymeric material now, used at present the cancellous bone fracture internal fixation screw made by the polylactic acid reinforcing material etc. clinically, also find the pure Poly-L-lactic acid of human (PLLA) is arranged or/and poly-dl-lactide (the square or cylindrical intervertebral fusion device of poly (D, L-lactide) PDLLA) material carries out biomechanics Research and zoopery.The inventor is by medical research for many years, being intended to provides a kind of high strength for clinical, low modulus, good biocompatibility, have osteogenic induction and conduction function and the final cervical fusion cage of degraded and absorbed in vivo, according to bibliographical information PLA the nonspecific inflammation reaction is arranged in human body, incidence rate is more than 5%, we are with alkaline HAp superfine powder and PLLA Composite Preparation novel cervical vertebra Invasive lumbar fusion device, purpose be bioactive ceramics HAp can in and the faintly acid that produces of PLLA degraded, significantly reduce the incidence rate of non-bacteria inflammation reaction, and increase osteogenic induction activity, discover that the back that implants is along with fusion device is constantly degraded, the HAp granule exposes gradually and is dispersed in device surface, make between material and bone interface and produce good binding, induce and promote osteoblast, fibroblasticly stick and grow, simultaneously the Ca that goes out of HAp particulate breakup ²⁺, P ³⁺Ion is promoted the calcification of collagen fiber in new bone formation process.

Summary of the invention

This utility model technical issues that need to address, be in the prior art, the weak points such as syncretizing effect that cervical fusion cage lacks the favorable mechanical compressive strength and becomes reconciled with the elastic modelling quantity of human body bone photo coupling, and redesign a kind of have good mechanical compressive strength, good biocompatibility, the final cervical fusion cage of degraded and absorbed in vivo.The purpose of this utility model, rely on following technical proposals to realize, a kind of biological degradable cervical fusion cage, constitute the garden column by macromolecule polymeric material, it is characterized in that profile is the wedge shape garden column that do not wait of garden end face up and down, the surperficial car of post has screw thread, the garden end face has the groove that matches with screwdriver, and column inside, wedge shape garden has the tunnel that traverses.The hole of the broken bone of put into local excision residue vertebral body that has between described tunnel and fusion device bottom surface, gelfoam, people's osteogenesis protein factor.Described Invasive lumbar fusion device, Poly-L-lactic acid in its macromolecule polymeric material (PLLA) and the shared part by weight of hydroxyapatite (HAp) superfine powder are 65/35.Groove is the placement location sign, and it is parallel consistent with intervertebral space that fusion device is inserted the back, guarantees that the body tunnel links to each other with last hypocentrum, and described thread surface is convenient to the implantation of fusion device, and reaches stability at once.The beneficial effects of the utility model are, this product provides a kind of high strength, low modulus, and good biocompatibility has osteogenic induction and conduction function, and the final cervical fusion cage of degraded and absorbed in vivo.

Description of drawings

Fig. 1 is a biological degradable cervical fusion cage outline drawing

Fig. 2 a-Fig. 2 b is use of this fusion device and state.

The specific embodiment

With reference to Fig. 1, the shape of product of expression this utility model biological degradable cervical fusion cage, wherein fusion device 1 is the wedge shape garden column that do not wait of garden end face up and down, there is a groove 2 that supplies screwdriver to match the lower surface, column side surface car has screw thread 3, fusant wedge shape garden column-shaped internal section has one and traverses logical tunnel 4, and groove 2 is perpendicular under tunnel direction and the lower surface.Fig. 2 a represents to implant the preceding punching state of this fusion device, and Fig. 2 b is the situation after fusion device is implanted.

Claims

1, a kind of biological degradable cervical fusion cage, constitute the garden column by macromolecule polymeric material, it is characterized in that, profile is the wedge shape garden column that do not wait of garden end face up and down, post surface car has screw thread, garden, end end face has the groove that matches with screwdriver, and column inside, wedge shape garden has the tunnel that traverses.

2, a kind of biological degradable cervical fusion cage according to claim 1 is characterized in that, the hole of the broken bone of put into local excision residue vertebral body that has between described tunnel and fusion device bottom surface, gelfoam, people's osteogenesis protein factor.

3, a kind of biological degradable cervical fusion cage according to claim 1 is characterized in that, described Invasive lumbar fusion device, and Poly-L-lactic acid PLLA and the shared part by weight of hydroxyapatite HAp superfine powder are 65/35 in its macromolecule polymeric material.