CN2544271Y - Dot printing needle set for microarray use - Google Patents
Dot printing needle set for microarray use Download PDFInfo
- Publication number
- CN2544271Y CN2544271Y CN 02236170 CN02236170U CN2544271Y CN 2544271 Y CN2544271 Y CN 2544271Y CN 02236170 CN02236170 CN 02236170 CN 02236170 U CN02236170 U CN 02236170U CN 2544271 Y CN2544271 Y CN 2544271Y
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- China
- Prior art keywords
- seal
- needle
- seal pin
- microarray
- pin
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- Expired - Lifetime
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Abstract
A point printing pin group used for a micro-array can be supplied to use for micro-array point printing, comprising a clamp, a plurality of point printing pins, wherein, a plurality of grooves are carved on a pin axis of each point printing pin so as to reduce weight and exhaust gas and remove chips; the top end of the pin axis is provided with a stopper which is used for preventing fall and rotation; a pinpoint plane which is formed by controlling the lower edge surface of the stopper and the length of the pinpoint leads a plurality of point printing pins to deal with point printing at the same time; each point printing pin can combine the pin axis with light material and a strengthened pinhead with bi-material; the solid lubrication is used in the pin axis to lower the weight of the point printing pin and reduce the change of compression and load of the pinpoint, thus prolonging the service life of the point printing pin and ensuring good result of point printing.
Description
(1) technical field
The utility model is in fields such as biomedicine, biological chemistry or molecular biosciences, relates to a kind of microarray with a some seal pin group, is meant a kind of microarray that is used on biochip seal pin group especially.
(2) background technology
As shown in Figure 1, existing microarray point printing device 6 is to be used for biological or chemical sample liquids point with trace to print carrier 100 surfaces that are positioned at this printing device 6 belows to, prints liquid with a microarray point that forms these samples.This printing device 6 comprises a movable block 61, and several are set up in the open flume type point seal pin 62 of this movable block 61.This movable block 61 can be driven the ground straight line drive these some seal 62 pins and carry out a seal near a carrier 100 flushly, and after touching this carrier 100, the needle point of these some seal pin 62 bottoms promptly drives it away from this carrier 100, discharge too much liquid (liquid volume of general every bit is 2pL～2nL), and these some seal pins 62 are to arrange to reach microarray point with lattice-array form very closely to print purpose to prevent to touch overlong time.
The end face 611 of this movable block 61 forms several parallel spill guide grooves 612 through processing.And these some seal pins 62 lean in these spill guide grooves 612 by the bottom surface of these limited blocks 621.In when seal, these limited blocks 621 can upwards be passed makes that its bottom surface is away from these spill guide grooves 612.Though each spill guide groove 612 degree of depth that processed should equate in principle, but because be to process respectively, so still there is certain tolerance value, with the angle than microcosmic is different dark, so can make the needle point 622 of each some seal pin 62 highly in fact differ, that is be not all in the same plane, when putting seal downwards, can excessively touch the phenomenon of this carrier 100 by generating unit minute needle point 622, and a printing matter is descended.In addition, because the axle body 623 of every bit seal pin 62 is to be arranged in this movable block 61, via slide up and down repeatedly can with these movable blocks 61 in produce break flours or produce vent plug for leg 614 friction in its each duct that wears, so very easily be blocked in the gap of this axle body 623 and 614 of legs, it is can't be free more sagging and lose a seal function to make that this point prints pin 62.
In addition, another kind of on the market existing microarray point printing device (not shown) comprises a hollow movable block, and utilizes several springs to be hung at several capillary type point seal pins of this movable block inside top surface.Owing to can being compressed, these springs produce elastic force after these needle points touch this carrier, and the needle point bore of general capillary type point seal pin is minimum, 50～200mm only has an appointment, when these needle points touch this carrier, except will bearing a weight of seal needle shaft body, therefore also can be subjected to above-mentioned elastic force and press down, very easily cause the needle point pressurized excessive and damage.
Therefore, how making needle points of these some seal pins all be positioned at same plane, avoid axle body to block the gap because of the abrasive action piece produces break flour, and avoid the needle point pressurized excessive and damage, is that the utmost point is treated improved problem in the manufacturing of microarray point printing device.
(3) utility model content
The purpose of this utility model is to provide a kind of needle point of seal pin that makes to be positioned at same plane, to offer the groove weight reduction avoiding the needle point pressurized excessive at axle body, and impose in the axle body surface solid lubrication with the microarray of the resistance of reducing friction with a some seal pin group.
The purpose of this utility model is achieved in that the design includes a chuck and several some seal pins, described chuck offers several storage tanks, these some seal pins can be in the storage tank of chuck moving linearly, wherein said every bit seal pin includes a needle shaft and one and the syringe needle that is connected with of needle shaft, and the surface of this needle shaft is formed with several grooves separately.
End at described needle shaft has an anti-scotch that falls and rotate, and rotates and falls from chuck with restriction point seal pin, and the lower edge face of this scotch just in time touches the last plane of chuck, so that the needle point of these some seal pins forms a needle point plane.By several grooves, do not alleviate a weight of seal pin only, this groove also has exhaust and the chip removal function, can make needle shaft be free to slide the work of smooth work point seal in chuck.The needle point plane guarantees then can print with time point for several some seal pins, and guarantees that certain some seal effect is arranged.In addition, the needle shaft that some seal pin can be light material combines with two materials of strong syringe needle, applying solid lubrication on the needle shaft handles, the practice of these lightweights, lower resistance, to alleviate a seal pin weight greatly and reduce needle point pressurized load variations, and more can prolong a seal pin serviceable life and guarantee that a seal is respond well.
Microarray of the present utility model has the following advantages with some seal pin group:
One, the life-span is long:
Microarray of the present utility model has groove with delineation on the needle shaft of some seal pin group utilization point seal pin, except that can alleviating a weight of seal pin, and exhaust and chip removal function is arranged, and can make needle shaft be free to slide the work of smooth work point seal in chuck; Simultaneously, the needle shaft that some seal pin can be light material combines with two materials of strong syringe needle, and these light-weighted practices will alleviate a seal pin weight and reduction needle point pressurized load variations greatly, prints pin serviceable life and more can prolong.
Two, seal consistance:
Microarray of the present utility model has an anti-scotch that falls and rotate with some seal pin group on the top of needle shaft, the length of control scotch lower edge face and needle point, to form the needle point face of some seal pin on chuck, then can print with time point, and guarantee that certain some seal effect is arranged for several some seal pins.
Three, action is smooth and easy:
Microarray of the present utility model also utilizes the needle shaft surface to be coated with the material of one deck such as low-friction coefficients such as quasi cobalt carbon diaphragm, molybdenum disulfide and Teflon with some seal pin group, with the frictional resistance between the storage tank that lowers needle shaft and chuck, this applies the solid lubrication processing on needle shaft can make the action of every bit seal pin more smooth and easy.
For further specifying above-mentioned purpose of the present utility model, design feature and effect, the utility model is described in detail below with reference to accompanying drawing.
(4) description of drawings
Fig. 1 is the cross-sectional schematic that an existing some printing device is positioned at carrier top.
Fig. 2 is the utility model microarray is positioned at carrier top with first preferred embodiment of some seal pin group a three-dimensional view.
Fig. 3 is the sectional view along Fig. 2 center line III-III.
Fig. 4 is the stereographic map that a bit prints pin of first preferred embodiment among Fig. 2.
Fig. 5 is the utility model microarray with second a preferred embodiment figure of some seal pin group, and the stereographic map of this some seal pin illustrate between the needle shaft that a little prints pin and syringe needle it is that pattern with different materials combines.
(5) embodiment
Shown in Fig. 2,3,4, microarray of the present utility model comprises one with some seal pin group 1 and offers the chuck 2 of several storage tanks 20, and can print pins 3 by several points of moving linearly in the storage tank 20 of chuck 2.This some seal pin 3 includes a needle shaft 33 and one and the syringe needle 34 that is connected with of needle shaft 33, and the surface of this needle shaft 33 is formed with several grooves 331 separately.
In addition, one end of needle shaft 33 has a scotch 31, these scotch 31 peripheries are formed with two planes 312 in case stop seal pin 3 rotates in storage tank 20, and these scotch 31 end faces are formed with a supporting part 310 in addition, the lower edge face 313 of this supporting part 310 just in time touches the last plane 21 of chuck 2, in case stop seal pin 3 falls from chuck 2.Therefore need only the last plane 21 of time processing chuck 2 as reference field, control every bit seal pin 3 again by the supporting part 310 lower edge faces 313 of scotch 31 distance to the needle point 341 of syringe needle 34, can make the needle point 341 of every bit seal pin 3 on microarray form a needle point plane 5, so, in a seal, can reach the consistance of a seal, not print asynchronism(-nization) and print the bad disappearance of effect a little and do not have 3 on every bit seal pin.
In addition, because the operation of some seal is to make a seal pin 3 moving linearly and knock carrier 100 surfaces in the storage tank 20 of chuck 2, solution is transferred on the carrier 100, therefore, the groove 331 that needle shaft 33 surfaces form, do not alleviate some the weight of seal pin 3 itself only, can't bear some the strength of seal pin 3 freely falling bodies when knocking this carrier 100 and damage with the needle point 341 that prevents this syringe needle 34, and this groove 331 also helps getting rid of needle shaft 33 in storage tank 20 during moving linearly and storage tank 20 surface friction institute fecula bits and have scavenging action concurrently, causes the phenomenon that can't move up and down or cause each some seal pin 3 highly to differ glibly to prevent to block gap or vent plug.
In the present embodiment, this some seal pin 3 is that stainless steel is made, 33 of this syringe needle 34 and needle shafts are secure engagement, can be that identical material is one-body molded made, can also be unlike material through welding or gummed mode or wringing fit is affixed forms, and these needle shaft 33 surfaces are coated with one deck low-friction coefficient material to lower and the frictional resistance of 20 of the storage tanks of chuck 2, and this low-friction coefficient material is to can be quasi cobalt carbon diaphragm, molybdenum disulfide and Teflon etc.
As shown in Figure 5, the utility model microarray is similar to this first preferred embodiment with second preferred embodiment of some seal pin group, different places are, the needle shaft 33 and 34 at the syringe needle of this some seal pin 3 are to combine in departing fixing mode, therefore can replace the needle shaft 33 or the syringe needle 34 of unlike material according to different needs, to reach light-weighted purpose.
Certainly, those of ordinary skill in the art will be appreciated that, above embodiment is used for illustrating the utility model, and be not to be used as qualification of the present utility model, as long as in connotation scope of the present utility model, all will drop in the scope of the utility model claims variation, the modification of the above embodiment.
Claims (7)
1. a microarray prints the pin group with point, include a chuck and several some seal pins, described chuck offers several storage tanks, these some seal pins can be in the storage tank of chuck moving linearly, it is characterized in that described every bit seal pin includes a needle shaft and one and the syringe needle that is connected with of needle shaft, the surface of this needle shaft is formed with several grooves separately.
2. microarray as claimed in claim 1 prints the pin group with point, an end that it is characterized in that described needle shaft has an anti-scotch that falls and rotate, the lower edge face of this scotch just in time touches the last plane of described chuck, so that the needle point of these some seal pins forms a needle point plane.
3. microarray as claimed in claim 1 is characterized in that with some seal pin group the needle shaft surface of described some seal pin is coated with one deck low-friction coefficient material, and this low-friction coefficient material is to can be quasi cobalt carbon diaphragm, molybdenum disulfide and Teflon etc.
4. microarray as claimed in claim 1 is characterized in that with some seal pin group the needle shaft of described some seal pin is to can be combining of different materials with syringe needle.
5. microarray as claimed in claim 1 is with a some seal pin group, is to engage in the gummed mode between the needle shaft that it is characterized in that described some seal pin and syringe needle.
6. microarray as claimed in claim 1 is with a some seal pin group, is to engage in the wringing fit mode between the needle shaft that it is characterized in that described some seal pin and syringe needle.
7. microarray as claimed in claim 1 is with a some seal pin group, is to engage with welding manner between the needle shaft that it is characterized in that described some seal pin and syringe needle.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 02236170 CN2544271Y (en) | 2002-05-24 | 2002-05-24 | Dot printing needle set for microarray use |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 02236170 CN2544271Y (en) | 2002-05-24 | 2002-05-24 | Dot printing needle set for microarray use |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN2544271Y true CN2544271Y (en) | 2003-04-09 |
Family
ID=33710539
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 02236170 Expired - Lifetime CN2544271Y (en) | 2002-05-24 | 2002-05-24 | Dot printing needle set for microarray use |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN2544271Y (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007071174A1 (en) * | 2005-12-23 | 2007-06-28 | Capitalbio Corporation | Bubble-resistant injector port for fluidic devices |
| CN107512081A (en) * | 2017-07-31 | 2017-12-26 | 北京康亿鸿科技发展有限公司 | Fluid delivery structure and the fluid delivery system with the fluid delivery structure |
-
2002
- 2002-05-24 CN CN 02236170 patent/CN2544271Y/en not_active Expired - Lifetime
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007071174A1 (en) * | 2005-12-23 | 2007-06-28 | Capitalbio Corporation | Bubble-resistant injector port for fluidic devices |
| CN107512081A (en) * | 2017-07-31 | 2017-12-26 | 北京康亿鸿科技发展有限公司 | Fluid delivery structure and the fluid delivery system with the fluid delivery structure |
| CN107512081B (en) * | 2017-07-31 | 2019-09-10 | 北京康亿鸿科技发展有限公司 | Fluid delivery structure and fluid delivery system with the fluid delivery structure |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C17 | Cessation of patent right | ||
| CX01 | Expiry of patent term |
Expiration termination date: 20120524 Granted publication date: 20030409 |