CN2424776Y - Multi-functional blood purifying machine - Google Patents
Multi-functional blood purifying machine Download PDFInfo
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- CN2424776Y CN2424776Y CN 00223151 CN00223151U CN2424776Y CN 2424776 Y CN2424776 Y CN 2424776Y CN 00223151 CN00223151 CN 00223151 CN 00223151 U CN00223151 U CN 00223151U CN 2424776 Y CN2424776 Y CN 2424776Y
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Abstract
The utility model relates to a multifunctional blood purifying machine. The utility model comprises a flow breaker, a peristaltic pump, an automatic heparin pushing device, a filter, an air detector and a venous pressure detector. The utility model is characterized in that the utility model is also provided with a plasma separating unit, a plasma substitution unit, a double-filter plasma separating unit, and hemodialysis equipment; the units and the filter are connected to form different hematogenous pipelines and dialysate pipelines through medical flexible pipes. The utility model can be used for blood purification, such as plasma separation, plasma substitution, double plasma separation and substitution, hemodialysis, hemoperfusion, etc. The blood purification technology of the utility model is suitable for being popularized in hospitals of all levels, and the utility model has the advantages of low production cost and low use cost.
Description
This utility model relates to a kind of armarium, is specifically related to a kind of multi-functional hsempdiakysing systems.
In the prior art, conventional hsempdiakysing systems mostly is the import haemodialysis control unit, provides disposable use dialysis solution by the dedicated water blood processor, and the use cost height is bulky, and inconvenience is moved, and costs an arm and a leg.Chinese patent 89218500 disclosed " portable blood purifier " is for the apparatus for purifying blood of treatment human body poisoning usefulness, and is simple in structure, but function singleness, result of use is not good enough.Chinese patent 96233250 disclosed " the unidirectional circulating haemodialysis control unit of negative-pressure type " is realized the unidirectional circulation of dialysis solution by liquid pump, dialysis solution pipe and high low level case, need artificial preparation dialysis solution but exist, dialysate flow control is bad, complex operation, shortcomings such as functional defect.
The purpose of this utility model is to overcome the above-mentioned deficiency of prior art, a kind of dialysis solution that can prepare different proportion automatically is provided, realize unidirectional circulate and intelligence multiplexing, can carry out that blood plasma (with composition) separates, the metathetical multi-functional hsempdiakysing systems of blood plasma (and composition).
Realize above-mentioned purpose, this utility model adopts following proposal to realize: 8. multi-functional hsempdiakysing systems, comprise that flow plug, peristaltic pump, automatic heparin push away and help device, filter, air monitor, venous pressure detector, also be provided with plasma separating unit, plasmapheresis device, two hemofiltration slurry segregation apparatus and haemodialysis equipment, described device and filter be connected to form different bloody path pipelines and dialysis solution pipeline by flexible pipe for medical purpose.Described plasma separating unit is by LOAD CELLS, plasma collection container and blood plasma pump serial connection, and blood plasma pump one end is connected with filter, also is provided with the blood plasma pressure detector and detects the blood plasma loine pressure.Described plasmapheresis device is in series by flexible pipe for medical purpose by LOAD CELLS, displacement liquid container and displacement liquid pump, and displacement liquid pump one end is connected with the drop tube.Described pair of hemofiltration slurry segregation apparatus constitutes for the series connection of two-stage plasma separator, and second level plasma separator can be connected with first order plasma separator by blood plasma pump, also can directly be connected with the one-level plasma separator.Described haemodialysis equipment is made up of dialysis solution automatic ratio liquid mixing system, dialysis fluid circuit and monitoring system, dialysis automatic ratio liquid mixing system comprises dosing pump, liquid dispensing container, LOAD CELLS, diluent container, Fast Heating calorstat, dialysis solution preheater, former liquid container, transfer valve, concentration detector, Temperature Detector, connect by the dosing pipeline, and be provided with bridge-type dialysis solution pipeline connection dialysis solution automatic ratio liquid mixing system and dialysis fluid circuit.Described dialysis apparatus connects dialysis solution input, output pipe through bridge-type dialysis solution pipeline, and is respectively equipped with peristaltic pump adjustment ultrafiltration rate and ultrafiltration volume, realizes the volume control of ultrafiltration rate and ultrafiltration volume.Described filter can be filling apparatus, plasma separator or dialyser.
Adopt the multi-functional hsempdiakysing systems of this structure, can carry out the blood purification of functions such as separating plasma, displacement, dual separating plasma displacement, hemodialysis and hemoperfusion, can treat multiple disease and symptom, especially be fit to medical institutions at different levels and be used to give treatment to following disease:
1. autoimmune disease, for example: macroglobulinemia, cryoglobulinemia, rheumatoid arthritis, pneumorrhagia nephritis syndrome, hemophilia, myasthenia gravis, Rh blood group incompatibility, idiopathic thrombocytopenic purpura, post-transfusion purpura, autoimmune hemolytic anemia, diabetes, renal transplantation, bone marrow transplantation etc.
2. immune-complex disease (ICD), for example: systemic lupus erythematosus (sle), lupus nephritis, rapidly progressive glomerulonephritis, many tuberositys vasculitis etc.
3. unusual serum composition, for example: multiple myeloma, familial hypercholesterolemia etc.
4. kidney disease, for example: acute and chronic renal failure, each phase uremia etc.
5. medicine toxic poisoning, for example: drugs poisonings such as sedative hypnotics poisoning, psychosis poisoning, rat poison poisoning, organophosphate poisoning, alcoholism, heroin etc.
These facility have very strong adaptability, are fit to China hospitals at different levels and promote the blood purification technology, and product cost is low, and large-scale production and wide application prospect are wide.
The utility model is described in further detail below in conjunction with drawings and embodiments:
Fig. 1 is the multi-functional hsempdiakysing systems structural representation of this utility model;
Fig. 2 is this utility model hemoperfusion pipeline schematic diagram;
Fig. 3 is this utility model separating plasma pipeline schematic diagram;
Fig. 4 is this utility model plasmapheresis schematic diagram;
Fig. 5 is that the two filter method blood plasma components of this utility model separate the pipeline schematic diagram;
Fig. 6 is that another pair of this utility model filter method blood plasma components separates the pipeline schematic diagram;
Fig. 7 is that the two filter method blood plasma components of this utility model separate and displacement pipeline schematic diagram;
Fig. 8 is that another pair of this utility model filter method blood plasma components separates and displacement pipeline schematic diagram;
Fig. 9 is this utility model hemodialysis pipeline schematic diagram;
Figure 10 is another hemodialysis pipeline schematic diagram of this utility model.
Contour structures of the present utility model as shown in Figure 1.In Fig. 1, the 2nd, flow plug V6, the 3rd, peristaltic pump D4 (or claims roller pump, the drum pump), the 4th, automatic heparin injector, the 5th, filter F1 and clamper thereof, the 7th, air monitor G, the 8th, venous pressure detector P1, the 9th, peristaltic pump D3, the 12nd, liquid container C2, the 13rd, LOAD CELLS W2, the 14th, pressure detector P2, the 16th, peristaltic pump D1, the 17th, liquid container C1, the 18th, LOAD CELLS W1, the 19th, filter F2 and clamper thereof, the 21st, peristaltic pump D2, the 22nd, liquid reservoir A, the 23rd, Fast Heating calorstat, the 24th, dialysis solution preheater, the 26th, liquid reservoir B, the 27th, transfer valve V1, the 28th, concentration detector Ω, the 29th, Temperature Detector T, the 30th, transfer valve V2, the 31st, dialysis solution thermostat, the 32nd, transfer valve V3, the 33rd, transfer valve V4, the 35th, blood leakage detector L, the 36th, transfer valve V5, the 37th, waste collection container, the 38th, body, the 39th, accumulator box, the 40th, universal wheel, the 41st, operated key face, the 42nd, display screen, the 43rd, printer, the 44th, alarm, the 45th, emergency stop switch, the 46th, cover.
When patient is carried out disease treatment,, take different measure to dispose corresponding transducer potector, blood plasma pipeline, dialysis solution pipeline and blood purification equipment and get final product according to different diseases and symptom.
This utility model can be realized blood perfusion technique like this, and its pipeline schematic diagram as shown in Figure 2.By arterial blood pipeline 1, flow plug 2, blood pump 3, automatic heparin injector 4, filter F1-perfusion device 5 (or claiming charcoal kidney), drop tube 6 (or claiming air trap or bubble trap), air monitor 7, venous pressure detector 8, venous blood pipeline 9 compositions such as grade.
Patients'blood under the promotion of blood pump 3, enters perfusion device 5 by arterial blood pipeline 1; Automatically heparin injector 4 is injected blood by preset program with heparin, stops blood clotting; Blood flows into drop tube 6 deaerations after the detoxifcation of perfusion device, flow back to human body by the venous blood pipeline then.Whether the blood back by venous pressure detector 8 monitoring venous line is unobstructed, by the excess whether of the air content in air monitor 7 monitoring of blood.In case occur unusually, blood pump 3 can stop automatically, flow plug 2 can turn-off transducer potector; Machine sends sound and light signal simultaneously, waits for that the staff handles.
This utility model can be realized the separating plasma technology like this, and its pipeline schematic diagram as shown in Figure 3.The difference of it and aforementioned blood perfusion technique is to change blood perfusion device into Membrane Plasma Separator, and has increased corresponding plasma collection system.Promptly by arterial blood pipeline 1, flow plug 2, blood pump 3, automatic heparin injector 4, filter F1-Membrane Plasma Separator 5, drop tube 6 (or claiming air trap or bubble trap), air monitor 7, venous pressure detector 8, venous blood pipeline 9, blood plasma pump 10, blood plasma pipeline 11, plasma collection container 12, LOAD CELLS 13, blood plasma pressure detector 14 compositions such as grade.
The blood of human body under the promotion of blood pump 3, enters Membrane Plasma Separator 5 by the arterial blood pipeline; Automatically the heparin injector is injected blood by preset program with heparin, stops blood clotting; Under the promotion of blood plasma pump 10, flow into plasma collection container 12 at isolated blood plasma in the plasma separator, by the separation rate and the fractional dose of LOAD CELLS 13 monitoring blood plasma through the blood plasma pipeline; The remaining cell composition in the separated back of blood flows back to human body through drop tube 6 and venous blood pipeline 9.Whether the blood back by venous pressure detector 8 monitoring venous line is unobstructed, by the excess whether of the air content in air monitor 7 monitoring of blood, pressure condition by blood plasma pressure detector 14 monitoring plasma separator blood plasma sides, and compare with venous pressure detector 8, the transmembrane pressure of monitoring plasma separator avoids excessive transmembrane pressure to cause rupture of membranes.In case occur unusually, blood pump 3 and blood plasma pump 10 stop automatically, flow plug 2 can turn-off transducer potector; Machine sends sound and light signal simultaneously, waits for that the staff handles.
If in system,, only rely on the pressure of blood side and the gravity of nature to carry out separating plasma, then can not control the separating plasma rate, and the position of plasma collection container 12 should be lower than plasma separator without blood plasma pump 10.
This utility model can be realized the plasmapheresis technology like this, and its pipeline schematic diagram as shown in Figure 4.It is on the basis of aforementioned separating plasma technology, increases the displacement liquid feed system.Promptly by arterial blood pipeline 1, flow plug 2, blood pump 3, automatic heparin injector 4, filter F1-Membrane Plasma Separator 5, drop tube 6 (or claiming air trap or bubble trap), air monitor 7, venous pressure detector 8, venous blood pipeline 9, blood plasma pump 10, blood plasma pipeline 11, plasma collection container 12, LOAD CELLS 13, blood plasma pressure detector 14, displacement liquid pipeline 15, displacement liquid pump 16, displacement liquid container 17, LOAD CELLS 18 compositions such as grade.
Patients'blood under the promotion of blood pump 3, enters Membrane Plasma Separator F15 by the arterial blood pipeline; Automatically heparin injector 4 is injected blood by preset program with heparin, stops blood clotting; Under the promotion of blood plasma pump 10, flow into plasma collection container 12 (preparation abandons) at isolated blood plasma in the plasma separator F15, by the separation rate and the fractional dose of LOAD CELLS 13 monitoring blood plasma through the blood plasma pipeline; Displacement liquid by the displacement liquid pipeline, with the separated back remaining cell composition of blood together, flows back to human body through drop tube 6 and venous blood pipeline under the promotion of displacement liquid pump 16.By LOAD CELLS 18 monitoring replacement rate and replacement amounts, reach the purpose synchronous with separating plasma.Whether the blood back by venous pressure detector 8 monitoring venous line is unobstructed, by the excess whether of the air content in air monitor 7 monitoring of blood, pressure condition by blood plasma pressure detector 14 monitoring plasma separator F15 blood plasma sides, and compare with venous pressure detector 8, the transmembrane pressure of monitoring plasma separator F15 avoids excessive transmembrane pressure to cause rupture of membranes.In case occur unusually, blood pump 3, blood plasma pump 10 and displacement liquid pump 16 stop automatically, and flow plug 2 can turn-off transducer potector; Machine sends sound and light signal simultaneously, waits for that the staff handles.
Similarly, if in system without blood plasma pump 10 and displacement liquid pump 16, only rely on the pressure of blood side and the gravity of nature to carry out the input of separating plasma and displacement liquid, then can not control the replacement rate of the separation rate and the displacement liquid of blood plasma, and the position of plasma collection container 12 should be lower than plasma separator 5, and the position of displacement liquid container should be placed on higher position.
This utility model can be realized two filter method blood plasma components isolation technics like this, and its pipeline schematic diagram as shown in Figure 5.It is on the basis of aforementioned separating plasma technology, increases second level blood plasma components piece-rate system.By selecting appropriate filter F1 (membrane aperture is bigger) and F2 (membrane aperture is less) to realize that the composition of blood plasma separates.Promptly by arterial blood pipeline 1, flow plug 2, blood pump 3, automatic heparin injector 4, filter F1-Membrane Plasma Separator 5, drop tube (or claiming air trap or bubble trap) 6, air monitor 7, venous pressure detector 8, venous blood pipeline 9, blood plasma pump 10, blood plasma pipeline 11, composition plasma collection container 12, LOAD CELLS 13, blood plasma pressure detector 14, filter F2-separator of blood plasma components 19, secondary blood plasma pipeline 20, secondary blood plasma pump 21 compositions such as grade.
The blood of human body under the promotion of blood pump 3, enters Membrane Plasma Separator 5 by the arterial blood pipeline; Automatically heparin injector 4 is injected blood by preset program with heparin, stops blood clotting; Under the promotion of blood plasma pump 10, flow into separator of blood plasma components 19 at 5 li isolated blood plasma of plasma separator through blood plasma pipeline 11; The composition blood plasma of being separated by separator of blood plasma components 19 flows into composition plasma collection container 12, by the separation rate and the fractional dose of LOAD CELLS 13 monitoring composition blood plasma; Remaining blood plasma by secondary blood plasma pipeline, with the separated back remaining cell composition of blood together, flows back to human body through drop tube and venous blood pipeline under the promotion of secondary blood plasma pump 21.Whether the blood back by venous pressure detector 8 monitoring venous line is unobstructed, by the excess whether of the air content in air monitor 7 monitoring of blood, pressure condition by blood plasma pressure detector 14 monitoring plasma separators 5 blood plasma sides, and compare with venous pressure detector 8, the transmembrane pressure of monitoring plasma separator 5 avoids excessive transmembrane pressure to cause rupture of membranes.In case occur unusually, blood pump 3 and blood plasma pump 10,21 stop automatically, flow plug 2 can turn-off transducer potector; Machine sends sound and light signal simultaneously, waits for that the staff handles.Two filter method blood plasma components isolation technics can also realize that like this its pipeline schematic diagram as shown in Figure 6.The aperture of at this moment selected filter F15 film is less, and the aperture of filter F219 film is bigger.Promptly by arterial blood pipeline 1, flow plug 2, blood pump 3, automatic heparin injector 4, filter F1-separator of blood plasma components 5, drop tube 6 (or claiming air trap or bubble trap), air monitor 7, venous pressure detector 8, venous blood pipeline 9, blood plasma pump 10, blood plasma pipeline 11, composition plasma collection container 12, LOAD CELLS 13, blood plasma pressure detector 14, filter F2-separator of blood plasma components 19, composition blood plasma pipeline 20, composition blood plasma pump 21 compositions such as grade.
The blood of human body under the promotion of blood pump 3, enters separator of blood plasma components 5 by the arterial blood pipeline; Automatically heparin injector 4 is injected blood by preset program with heparin, stops blood clotting; 5 li of separator of blood plasma components, isolated more macromolecular blood plasma and blood cell composition continue to flow into separator of blood plasma components 19; 19 li of separator of blood plasma components, the composition blood plasma of separating flows into composition plasma collection container 12 under the promotion of blood plasma pump 21, by the separation rate and the fractional dose of LOAD CELLS 13 monitoring composition blood plasma; Under the promotion of blood plasma pump 10,, flow back to human body by the isolated blood plasma than micromolecule of separator of blood plasma components 5 through drop tube and venous blood pipeline with together from separator of blood plasma components 19 effusive blood cell compositions.Whether the blood back by venous pressure detector 8 monitoring venous line is unobstructed, by the excess whether of the air content in air monitor 7 monitoring of blood, pressure condition by blood plasma pressure detector 14 monitoring separator of blood plasma components 5 blood plasma sides, and compare with venous pressure detector 8, the transmembrane pressure of monitoring separator of blood plasma components 5 avoids excessive transmembrane pressure to cause rupture of membranes.In case occur unusually, blood pump 3 and blood plasma pump 10,21 stop automatically, flow plug 2 can turn-off transducer potector; Machine sends sound and light signal simultaneously, waits for that the staff handles.
This utility model can realize like this that two filter method blood plasma components separate and replacement technique, and its pipeline schematic diagram as shown in Figure 7.It is on the basis of aforementioned first kind of two filter method blood plasma components isolation technics, increases the displacement liquid feed system.Promptly by arterial blood pipeline 1, flow plug 2, blood pump 3, automatic heparin injector 4, filter F1-Membrane Plasma Separator 5, drop tube 6 (or claiming air trap or bubble trap), air monitor 7, venous pressure detector 8, venous blood pipeline 9, blood plasma pump 10, blood plasma pipeline 11, composition plasma collection container 12, LOAD CELLS 13, blood plasma pressure detector 14, displacement liquid pipeline 15, displacement liquid pump 16, displacement liquid container 17, LOAD CELLS 18, filter F2-separator of blood plasma components 19, secondary blood plasma pipeline 20, secondary blood plasma pump 21 compositions such as grade.
Patients'blood under the promotion of blood pump 3, enters plasma separator 5 by arterial blood pipeline 1; Automatically heparin injector 4 is injected blood by preset program with heparin, stops blood clotting; Under the promotion of blood plasma pump 10, flow into separator of blood plasma components 19 at 5 li isolated blood plasma of plasma separator through blood plasma pipeline 11; The composition blood plasma of being separated by separator of blood plasma components 19 flows into composition plasma collection container 12 (preparation abandons), by the separation rate and the fractional dose of LOAD CELLS 13 monitoring composition blood plasma; Displacement liquid by displacement liquid pipeline 15, flows to drop tube 6 under the promotion of displacement liquid pump 16, by LOAD CELLS 18 monitoring replacement rate and replacement amounts; Simultaneously at the blood plasma of 19 li remainders of separator of blood plasma components under the promotion of secondary blood plasma pump 21, by secondary blood plasma pipeline 20, coexist the remaining cell composition in the separated back of blood in the plasma separator 5 together, also flow into drop tube 6, flow back to human body through venous blood pipeline 9.Whether the blood back by venous pressure detector 8 monitoring venous line is unobstructed, by the excess whether of the air content in air monitor 7 monitoring of blood, pressure condition by blood plasma pressure detector 14 monitoring plasma separators 5 blood plasma sides, and compare with venous pressure detector 8, the transmembrane pressure of monitoring plasma separator 5 avoids excessive transmembrane pressure to cause rupture of membranes.In case occur unusually, blood pump 3, blood plasma pump 10,21 and displacement liquid pump 16 stop automatically, and flow plug V6 can turn-off transducer potector; Machine sends sound and light signal simultaneously, waits for that the staff handles.Two filter method blood plasma components separate with replacement technique can also realize that like this its pipeline schematic diagram as shown in Figure 8.It is on the basis of second kind of two filter method blood plasma components separate mode, increases the displacement liquid feed system.Promptly by arterial blood pipeline 1, flow plug 2, blood pump 3, automatic heparin injector 4, filter F1-separator of blood plasma components 5, drop tube 6 (or claiming air trap or bubble trap), air monitor 7, venous pressure detector 8, venous blood pipeline 9, blood plasma pump 10, blood plasma pipeline 11, composition plasma collection container 12, LOAD CELLS 13, blood plasma pressure detector 14, displacement liquid pipeline 15, displacement liquid pump 16, displacement liquid container 17, LOAD CELLS 18, filter F2-separator of blood plasma components 19, composition blood plasma pipeline 20, composition blood plasma pump 21 compositions such as grade.
Patients'blood under the promotion of blood pump 3, enters separator of blood plasma components 5 by arterial blood pipeline 1; Automatically heparin injector 4 is injected blood by preset program with heparin, stops blood clotting; 5 li of separator of blood plasma components, isolated more macromolecular blood plasma and cell composition continue to flow into separator of blood plasma components 19; 19 li of separator of blood plasma components, the composition blood plasma of separating flows into composition plasma collection container 12 (preparation abandons) under the promotion of blood plasma pump 21, by the separation rate and the fractional dose of LOAD CELLS 13 monitoring composition blood plasma; Displacement liquid by displacement liquid pipeline 16, flows to drop tube 6 under the promotion of displacement liquid pump 16, by LOAD CELLS 18 monitoring replacement rate and replacement amounts; Under the promotion of blood plasma pump 10,, also flow into drop tube 6 by the isolated blood plasma than micromolecule of separator of blood plasma components 5, flow back to human body through venous blood pipeline 9 with together from separator of blood plasma components 19 effusive blood cell compositions.Whether the blood back by venous pressure detector 8 monitoring venous line is unobstructed, by the excess whether of the air content in air monitor 7 monitoring of blood, pressure condition by blood plasma pressure detector 14 monitoring separator of blood plasma components 5 blood plasma sides, and compare with venous pressure detector 8, the transmembrane pressure of monitoring separator of blood plasma components 5 avoids excessive transmembrane pressure to cause rupture of membranes.In case occur unusually, blood pump 3, blood plasma pump 10,21 and displacement liquid pump 16 stop automatically, and flow plug 2 can turn-off transducer potector; Machine sends sound and light signal simultaneously, waits for that the staff handles.
This utility model can be realized hemodialysis technology like this, and its pipeline schematic diagram as shown in Figure 9.
By arterial blood pipeline 1, flow plug 2, blood pump 3, automatic heparin injector 4, dialyser 5, drop tube 6 (or claiming air trap or bubble trap), air monitor 7, venous pressure detector 8, venous blood pipeline 9 grades are formed blood circuit and monitoring system.
By dosing pump 16, liquid dispensing container 17, LOAD CELLS 18, diluent container 22, Fast Heating calorstat 23, dialysis solution preheater 24, dosing pipeline 25, former liquid container 26, transfer valve 27, concentration detector 28, Temperature Detector 29 grades are formed dialysis solution automatic ratio liquid mixing system.
By dialyser 5, peristaltic pump 10, ultrafiltration measuring container 12, LOAD CELLS 13, detection of negative pressure device 14, liquid dispensing container 17, LOAD CELLS 18, peristaltic pump 21, concentration detector 28, Temperature Detector 29, transfer valve 30, dialysis solution thermostat 31, transfer valve 32, transfer valve 33, bridge-type dialysis solution pipeline 34, blood leakage detector 35, transfer valve 36, useless dialysis solution collection container 37 grades are formed dialysis fluid circuit and monitoring system.
Before carrying out hemodialysis, earlier the A kind liquid for preparing is put into diluent container 22 (normally distilled water or pure water), B kind liquid is put into former liquid container 26 (normally concentrate dialysate).Make transfer valve 27 open A liquid, turn-off B liquid; Start dosing pump 16, A liquid is sucked in the dialysis solution preheater 31; Open the Fast Heating calorstat, with the preheating of A liquid (38 ± 1 ℃).After reaching predetermined temperature, transfer valve 27 is opened B liquid, turn-offs A liquid; Dosing pump 16 starts to be sent into B liquid in the liquid dispensing container 17, by the amount of sending into (the B liquid: A liquid=1: 34) of LOAD CELLS 18 monitoring B liquid; After reaching scheduled volume, transfer valve 27 is opened A liquid, turn-offs B liquid, A liquid is sent in the liquid dispensing container 17, by the amount of sending into of LOAD CELLS 18 monitoring A liquid,, monitor the temperature of the dialysis solution after preparing by Temperature Detector 29 equally again by the concentration of concentration detector 28 monitoring dialysis solution.
When carrying out hemodialysis, in blood circuit, patients'blood under the promotion of blood pump 3, enters dialyser 5 by arterial blood pipeline 1, and heparin injector 4 is injected blood by preset program with heparin automatically, stops blood clotting; Blood flows into drop tube 6 deaerations after dialyser 5 dialysis, flow back to human body by venous blood pipeline 9 then.Whether the blood back by venous pressure detector 8 monitoring venous line is unobstructed, by the excess whether of the air content in air monitor 7 monitoring of blood.
In dialysis fluid circuit, transfer valve 30 is opened dialysis circuit, transfer valve 32 is opened upper pipeline, is turn-offed lower pipeline, transfer valve 33 is opened lower pipeline, is turn-offed upper pipeline, transfer valve 36 is opened dialysis circuit, is turn-offed discharge pipe, then the dialysis solution in the liquid dispensing container 17 is pressed following path flows under the combined effect of peristaltic pump 21 and peristaltic pump 10:
Dialysis solution through transfer valve 30, through dialysis solution thermostat constant temperature, through the upper pipeline of transfer valve 32, under the promotion of solution feed pump 21, enters the inlet of dialyser 5 by flowing out in the liquid dispensing container 17; Flow out from the outlet of dialyser 5, through blood leakage detector 35, by peristaltic pump 10 sucking-offs, through transfer valve 36, the lower pipeline through transfer valve 33 is opened flows in the ultrafiltration measuring container 12 again.
By the situation of change of dialysis solution in LOAD CELLS 18 and the whole dialysis circuit of LOAD CELLS 13 monitorings, and carry out the ultrafiltration metering.Dialysis liquid measure in the establishing liquid container 17 is Q1; Dialysis liquid measure in dialysis fluid circuit and the dialyser 5 (dialysis solution priming volume) is Q2; When dialysis solution begins to enter ultrafiltration measuring container 12, when LOAD CELLS 13 detects weight change, the dialysis liquid measure that LOAD CELLS 18 is noted in the liquid dispensing container 17 is Q3, and Q3 will be the primary quantity (ultrafiltration volume that takes place when ignoring the dialysis solution preliminary filling) that carries out the ultrafiltration metering; When the dialysis fluid flow in the liquid dispensing container 17 was intact, the dialysis liquid measure in the LOAD CELLS 13 detected ultrafiltration measuring containers 12 was Q4.Then the dialysis liquid measure in dialysis circuit has following relation:
Primary quantity Q3=Q1-Q2
Ultrafiltration volume UF1=Q4-Q3
If peristaltic pump 21 is with the speed feed flow of 500ml/min, and peristaltic pump 10 under the appropriate situation of the ultrafiltrate coefficient of dialyser, just can be realized the volume control of ultrafiltration volume with the speed imbibition of 520ml/min.At this moment,
The ultrafiltration rate is: 520ml/min-500ml/min=20 ml/min
Ultrafiltration volume is: UF1=(Q3 ÷ 500ml/min) * 20 ml/min
The speed that changes peristaltic pump 10 just can change ultrafiltration rate and ultrafiltration volume.By the pressure condition of detection of negative pressure device 8 monitoring dialysers 5 dialysis fluid side, and compare with venous pressure detector 8, the transmembrane pressure of monitoring dialyser 5 avoids excessive transmembrane pressure to cause rupture of membranes; Detect in the dialysis solution by blood leakage detector 35 whether leakage blood is arranged.
When ultrafiltration volume does not reach predetermined value, dialysis solution will be re-used.At this moment in dialysis fluid circuit, transfer valve 30 keeps dialysis circuit open-minded, transfer valve 32 is opened lower pipeline, is turn-offed upper pipeline, transfer valve 33 is opened upper pipeline, is turn-offed lower pipeline, transfer valve 36 is opened dialysis circuit, is turn-offed discharge pipe, then the dialysis solution in the ultrafiltration measuring container 12 is pressed following path flows under the combined effect of peristaltic pump 21 and peristaltic pump 10:
Dialysis solution through the upper pipeline of transfer valve 33, under the promotion of peristaltic pump 21, enters the inlet of dialyser 5 by flowing out in the ultrafiltration measuring container 12; Flow out from the outlet of dialyser 5 again,,,,,,, flow in the liquid dispensing container 17 through transfer valve 30 through dialysis solution thermostat constant temperature through the lower pipeline of transfer valve 32 through transfer valve 36 by peristaltic pump 10 sucking-offs through blood leakage detector 35.
At this moment the dialysis liquid measure Q4 in the ultrafiltration measuring container 12 becomes initial value again.When Q4 has flowed, the liquid measure Q5 that in liquid dispensing container 17, obtains dialysing, then this circulation ultrafiltration volume is
UF2=Q5-Q4
Control mode also can get by measure
UF2=(Q4÷500ml/min)×20?ml/min
Ultrafiltration volume accumulative total is UF=UF1+UF2
In liquid dispensing container 17, monitor the concentration of dialysis solution, and control the automatic ratio liquid mixing system and carry out concentration adjustment (adding A liquid or B liquid), reach the purpose of proofreading and correct dialysate concentration by concentration detector 28; Temperature by the dialysis solution after the Temperature Detector 29 monitoring preparations.Dialysis liquid measure Q6 after the correction becomes dialysis solution circulation initial value next time again, and dialysis solution is from liquid dispensing container 17, and through dialyser 5, the flow process that flows into ultrafiltration measuring container 12 is the same with aforesaid that time, no longer repeated description.
To produce each circulation ultrafiltration volume like this
UF3=Q7-Q6 or UF3=(Q6 ÷ 500ml/min) * 20ml/min
UF4=Q8-Q7 or UF4=(Q7 ÷ 500mml/min) * 20ml/min
Ultrafiltration volume accumulative total is UF=UF1+UF2+UF3+UF4+
In ultrafiltration measuring container 12, when the dialysis liquid measure reaches predetermined ultrafiltration volume, transfer valve 36 is opened discharge pipe, is turn-offed dialysis circuit, transfer valve 33 is opened upper pipeline, is turn-offed lower pipeline, transfer valve 32 is opened lower pipeline, is turn-offed upper pipeline, then the dialysis solution in the ultrafiltration measuring container 12 is pressed following path flows under the combined effect of peristaltic pump 21 and peristaltic pump 10:
Dialysis solution through the upper pipeline of transfer valve 33, under the promotion of peristaltic pump 21, enters the inlet of dialyser 5 by flowing out in the ultrafiltration measuring container 12; Flow out from the outlet of dialyser 5 again,,,, flow into the waste collection container through transfer valve 36 by peristaltic pump 10 sucking-offs through blood leakage detector 35.
Meanwhile, the automatic ratio liquid mixing system starts, and carries out the preparation of new dialysis solution in liquid dispensing container 17.In case after the dialysis fluid flow in the ultrafiltration measuring container 12 was intact, machine entered the dialysis treatment of a new round.Its process is identical with aforementioned process.
Just the ultrafiltration volume of this moment accumulative total should add the ultrafiltration volume that time, dialysis was produced before dialysis solution was discharged, that is: UF=UF1+UF2+UF3+UF4+ automatically ... + UFn
UFn=UFn-1+(UFn-1-UFn-2)
=2UFn-1-UFn-2
Or: UFn=(Qn-1 ÷ 500ml/min) * 20ml/min
Reciprocal thus, finish the overall process of hemodialysis.
The situation at each each position of detector monitors in blood circuit and dialysis fluid circuit, in case occur unusually, blood pump 3, peristaltic pump 10, peristaltic pump 21 and dosing pump 16 stop automatically, flow plug 2 can turn-off transducer potector; Machine sends sound and light signal simultaneously, waits for that the staff handles.
The volume control of ultrafiltration volume when this utility model can also be realized hemodialysis like this, its pipeline schematic diagram as shown in figure 10.
In Figure 10,10 is two-tube peristaltic pump, and it enters the mouth the dialysis solution that dialysis solution is sent into dialyser 5 by a pipeline on one side, again dialysis solution is passed through the dialysis solution outlet sucking-off of another pipeline from dialyser 5 simultaneously.21 is the volume control pump, extracts the liquid feeding end that the part dialysis solution sends back to volume control pump 21 by it out from the dialysis solution arrival end of dialyser 5, so just can realize the volume control of ultrafiltration volume.
For example, the working flow of two-tube peristaltic pump 10 is 520ml/min, and the working flow of volume control pump 21 is 20ml/min.At this moment, the dialysate flow in the dialysis solution porch of dialyser 5 is:
520ml/min-20ml/min=500ml/min and dialysate flow in the dialysis solution exit of dialyser 5 remains 520ml/min.Realize that the ultrafiltration rate is:
520ml/min-500ml/min=20ml/min that is to say, by the flow of control volume control pump 21, just can control the ultrafiltration rate, the volume control of ultrafiltration volume when just having realized hemodialysis.
The operation principle of the other parts of hemodialysis pipeline schematic diagram shown in Figure 10 is similar to operation principle shown in Figure 9, no longer repeated description.
This utility model also can continue the arteriovenous ultrafiltration, continue various blood purification technology such as arteriovenous hemofiltration, simple blood ultrafiltration, hemodiafiltration, hemodialysis perfusion.
Claims (7)
1. multi-functional hsempdiakysing systems, comprise that flow plug, peristaltic pump, automatic heparin push away and help device, filter, air monitor, venous pressure detector, it is characterized in that: also be provided with plasma separating unit, plasmapheresis device, two hemofiltration slurry segregation apparatus and haemodialysis equipment, described device and filter be connected to form different bloody path pipelines and dialysis solution pipeline by flexible pipe for medical purpose.
2. hsempdiakysing systems as claimed in claim 1 is characterized in that: described plasma separating unit is by LOAD CELLS, plasma collection container and blood plasma pump serial connection, and blood plasma pump one end is connected with filter, also is provided with the blood plasma pressure detector and detects the blood plasma loine pressure.
3. hsempdiakysing systems as claimed in claim 1 is characterized in that: described plasmapheresis device is formed by the flexible pipe for medical purpose serial connection by LOAD CELLS, displacement liquid container and displacement liquid pump, and displacement liquid pump one end is connected with the drop tube.
4. hsempdiakysing systems as claimed in claim 1, it is characterized in that: described pair of hemofiltration slurry segregation apparatus constitutes for two-stage blood plasma series connection separator, second level plasma separator can be connected with first order plasma separator by blood plasma pump, also can directly be connected with the one-level plasma separator.
5. hsempdiakysing systems as claimed in claim 1, it is characterized in that: described haemodialysis equipment is made up of dialysis solution automatic ratio liquid mixing system, dialysis fluid circuit and monitoring system, dialysis solution automatic ratio liquid mixing system comprises dosing pump, liquid dispensing container, LOAD CELLS, diluent container, Fast Heating calorstat, dialysis solution preheater, former liquid container, transfer valve, concentration detector, Temperature Detector, connect by the dosing pipeline, and be provided with bridge-type dialysis solution pipeline connection dialysis solution automatic ratio liquid mixing system and dialysis fluid circuit.
6. hsempdiakysing systems as claimed in claim 5 is characterized in that: described dialysis apparatus connects dialysis solution input, output pipe through bridge-type dialysis solution pipeline, and is respectively equipped with the volume control that peristaltic pump is realized ultrafiltration rate and ultrafiltration volume.
7. the hsempdiakysing systems of stating as claimed in claim 1 is characterized in that: described filter can be filling apparatus, plasma separator or dialyser.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 00223151 CN2424776Y (en) | 2000-05-29 | 2000-05-29 | Multi-functional blood purifying machine |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 00223151 CN2424776Y (en) | 2000-05-29 | 2000-05-29 | Multi-functional blood purifying machine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN2424776Y true CN2424776Y (en) | 2001-03-28 |
Family
ID=33587745
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 00223151 Expired - Fee Related CN2424776Y (en) | 2000-05-29 | 2000-05-29 | Multi-functional blood purifying machine |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN2424776Y (en) |
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2005097231A1 (en) * | 2004-04-06 | 2005-10-20 | Shanghai Jiangxia Blood Technology Co., Ltd. | Extra-corporeal filter apparatus for removing lipids from plasma |
| CN104174080A (en) * | 2014-09-16 | 2014-12-03 | 王卫国 | Hemodialysis machine capable of independently adjusting dialysate concentration |
| CN105771011A (en) * | 2016-01-31 | 2016-07-20 | 陈雯 | Nephritis treatment periodic dialysis apparatus |
| CN106237413A (en) * | 2016-08-18 | 2016-12-21 | 陈雯 | Haemodialysis equipment |
| CN107754037A (en) * | 2017-11-22 | 2018-03-06 | 付娜娜 | A kind of Nephrology dept.'s haemodialysis equipment |
| CN110290819A (en) * | 2016-11-07 | 2019-09-27 | 卡萨布兰卡哈桑二世大学 | Portable ultrafiltration equipment |
| CN113633841A (en) * | 2021-08-05 | 2021-11-12 | 北京健帆医疗设备有限公司 | Pressure detection method for blood purification apparatus, and storage medium |
-
2000
- 2000-05-29 CN CN 00223151 patent/CN2424776Y/en not_active Expired - Fee Related
Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2005097231A1 (en) * | 2004-04-06 | 2005-10-20 | Shanghai Jiangxia Blood Technology Co., Ltd. | Extra-corporeal filter apparatus for removing lipids from plasma |
| CN104174080A (en) * | 2014-09-16 | 2014-12-03 | 王卫国 | Hemodialysis machine capable of independently adjusting dialysate concentration |
| CN105771011A (en) * | 2016-01-31 | 2016-07-20 | 陈雯 | Nephritis treatment periodic dialysis apparatus |
| CN106237413A (en) * | 2016-08-18 | 2016-12-21 | 陈雯 | Haemodialysis equipment |
| CN110290819A (en) * | 2016-11-07 | 2019-09-27 | 卡萨布兰卡哈桑二世大学 | Portable ultrafiltration equipment |
| US11666692B2 (en) | 2016-11-07 | 2023-06-06 | Hassan Ii University Of Casablanca | Portable ultrafiltration device |
| CN107754037A (en) * | 2017-11-22 | 2018-03-06 | 付娜娜 | A kind of Nephrology dept.'s haemodialysis equipment |
| CN113633841A (en) * | 2021-08-05 | 2021-11-12 | 北京健帆医疗设备有限公司 | Pressure detection method for blood purification apparatus, and storage medium |
| CN113633841B (en) * | 2021-08-05 | 2024-03-19 | 北京健帆医疗设备有限公司 | Pressure detection method for blood purification device, and storage medium |
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| C14 | Grant of patent or utility model | ||
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| C19 | Lapse of patent right due to non-payment of the annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |