CN2276635Y - Automatic enzyme labelling board washing machine - Google Patents
Automatic enzyme labelling board washing machine Download PDFInfo
- Publication number
- CN2276635Y CN2276635Y CN 96207598 CN96207598U CN2276635Y CN 2276635 Y CN2276635 Y CN 2276635Y CN 96207598 CN96207598 CN 96207598 CN 96207598 U CN96207598 U CN 96207598U CN 2276635 Y CN2276635 Y CN 2276635Y
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- cleaning head
- worktable
- vertical movement
- casing
- microplate washer
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Abstract
The utility model relates to an automatic enzyme-labeling board washing machine, which comprises a box body and a vertical moving mechanism, wherein, a control board of an electric appliance and a pump are arranged in the box body; the vertical moving mechanism is provided with a limiting device; a cleaning head is connected to the vertical moving mechanism; the front end of the box body is provided with a working table which is connected and provided with a horizontal moving mechanism; one end of the horizontal moving mechanism provided with another limiting device; the limiting device of the vertical moving mechanism is arranged at the upper end of the vertical moving mechanism; a row of water absorbing needles and a row of water injecting needles are arranged on the cleaning head. The utility model has flexible cleaning modes, and is suitable for various experiments of different scales; the utility model has the advantages of good operability, small size, high moving precision and simple structure.
Description
The utility model relates to the automated cleaning equipment of washing titer plate in a kind of clinical medical inspection and the chemical analysis, is a kind of automatic ELIAS microplate washer specifically.
Solid-phase enzyme immunoassay (BLISE) is a kind of important technology in the immunity inspection.In the ELISE experiment, washing plate is topmost key technology, because ELISE is the enzyme labeling thing that comes separated free by washing, removes by washing and to remain in nonspecific interference adsorbate in the material that do not combine in the plate hole and the course of reaction with solid phase antigen body (or antibody).The quality of washing plate is directly connected to the success or failure of experiment, adopts and accurately and completely washes the plate mode, can make the sensitivity of ELISE experiment improve several times.
The existing plate machine of washing, as Chinese patent notification number CN2197666Y " automatic washer ", get final product the vertical movement cleaning head of tangential movement again but include one, this cleaning head is divided into two groups, one is assembled with many pieces of water filling heads, is used for injecting washing lotion in the hole of ELISA Plate; Many pieces of suction lifts of another assembling are used for the soiling solution in the corresponding hole is sopped up.The vertical movement of cleaning head is made up of a pinion and rack, its location be by be located at vertical mechanism up and down the photoelectric tube at two ends realize; The location of tangential movement then is provided with corresponding photoelectric tube according to the number of washing plate.Though this automatic washer can be finished the robotization of washing plate work, but still there is following defective:
1, suction lift in the cleaning head and water filling head branch are arranged, wherein the pin number of suction lift and water filling head equates with the hole count of ELISA Plate, therefore can only put in order the whole plate ground of plate and clean, and can only clean the fixedly ELISA Plate of hole count, the mode of cleaning is dumb, and is unsuitable for some small-scale experiments; This in addition structural volume is big and heavy, and is inharmonious with breadboard environment;
2, the vertical movement mechanism of cleaning head is set up on the horicontal motion mechanism, but makes cleaning head get final product tangential movement vertical movement again, and this kind motion of mechanism mode must take bigger space, and the volume of washing the plate machine is increased; For to make cleaning head can have the space of vertical movement, its horicontal motion mechanism must be positioned at casing position on the upper side in addition, and integrally-built rigidity is bad; Need be connected with fluid injection flexible pipe and pipetting hose on the cleaning head, when cleaning head carried out tangential movement, its scope that moves was bigger, and connect thereon flexible pipe also carry out thereupon in a big way move inconvenient operation;
3, the vertical movement of cleaning head is to constitute with pinion and rack, and the transmission accuracy of this kind mode is lower, and does not have self-locking property, is easy to generate the action of downslide under the situation of mechanism's deadweight;
4, with the power of micromotor as tangential movement and vertical movement, for guaranteeing the accurate of this motion, adopt the detent mechanism of photoelectric tube, in horicontal motion mechanism, then need be provided with and the corresponding photoelectric tube of plate number, this structure does not have self-locking performance because of motor, easily produces the inaccurate of location, location structure complexity in addition under its action of inertia, thereby the increase cost of manufacture increases the volume of washing the plate machine.
The purpose of this utility model is to provide a kind of automatic ELIAS microplate washer, has cleaning way flexibly, enlarges its scope of application, improves its operability; Reduce to wash the volume of plate machine, improve its kinematic accuracy; Simplified structure reduces cost.
The purpose of this utility model is achieved in that a kind of automatic ELIAS microplate washer, include casing, be equiped with an appliance controling plate and pump in this casing, also include a vertical movement mechanism that drags by motor, this vertical movement mechanism is provided with stop means, cleaning head is connected in this vertical movement mechanism, the front end of casing is provided with one can carry the worktable of ELISA Plate, it is characterized in that described worktable is provided with a horicontal motion mechanism that is dragged by motor, an end of this horicontal motion mechanism is provided with a stop means; The stop means of vertical movement mechanism then is arranged at the upper end of this vertical movement mechanism; Described cleaning head is provided with row's suction pin and row's water injection needle.
The utility model also can be realized by following measure, described vertical movement mechanism comprises that one is fixed in the support of casing, set firmly a motor on the support, the output terminal of this motor is connected with the screw thread elevating mechanism, this screw thread elevating mechanism reaches the nut that matches with it by the screw rod that is connected in motor output end and constitutes, a cleaning head carriage is connected on this nut, described cleaning head can be plugged in the external part of this cleaning head carriage, be positioned on the support of thread segment and be symmetrically arranged with guide rail, be folded with rolling body between cleaning head and guide rail; Described horicontal motion mechanism is made of a guide piece and an actuator; Described guide piece can be two horizontally disposed feed rods, and this feed rod is arranged in worktable; Its actuator includes the cog belt that is fixed in worktable, and an end of this cog belt is provided with a belt pulley that is connected in motor output end, and the other end is provided with a passive belt wheel that is connected in casing; Described guide piece also can be two horizontally disposed dovetail grooves, and the dove-tail form that is complementary with this dovetail groove is arranged in worktable carriage bottom; Screw rod that its actuator also can be connected by motor output end and the nut that is fixedly arranged on the worktable carriage constitute; Water injection needle on the cleaning head is shorter than the suction pin; Described pump can be the double end micropump, and this double end micropump is connected in surge flask and bottle for handling liquid toilet or cosmetic substance; The stop means of vertical mechanism is made of with the optocoupler bent plate that is connected on the nut the optocoupler that is arranged on the support; The stop means of described horizontal mechanism is made of with the optocoupler bent plate that is connected on the worktable carriage the optocoupler that is arranged on the casing.
It is significant that the utility model is compared effect with prior art: 1, cleaning head has only fluid injection and each row's pin of imbibition in the utility model, a row each capable of washing, the user can select the hole count of cleaning and the mode of cleaning according to the requirement of oneself like this, needn't put in order the whole plate ground of plate cleans, dirigibility with cleaning, be not only applicable to large hospital and use, also be applicable to small hospital or small-scale work for inspection, the scope of application is wider; 2, cleaning head only is in vertical motion in the utility model, carry out tangential movement by worktable, shared activity space is little, dwindles the volume of body effectively, the scope of activities that is connected in fluid injection flexible pipe on the cleaning head or pipetting hose is less, helps prolonging its serviceable life; Horicontal motion mechanism is positioned at the below of casing, and the stability and the rigidity of total are better; 3, the vertical movement mechanism in the utility model adopts the screw thread elevating mechanism, has improved the precision of transmission and the self-locking performance of mechanism; 4, the power vertical and horicontal motion mechanism in the utility model all adopts stepper motor, accurate positioning, and control is simple, and a very high kinematic accuracy not only can be provided, and simplified structure.
The explanation of accompanying drawing drawing:
Fig. 1 is a structural representation of the present utility model;
Fig. 2 is the structural representation of vertical movement mechanism of the present utility model;
Fig. 3 is that the A of Fig. 2 is to view;
Fig. 4 is the structural representation of horicontal motion mechanism embodiment one in the utility model;
Fig. 5 is the vertical view of Fig. 4;
Fig. 6 is the structural representation of horicontal motion mechanism embodiment two of the present utility model;
Fig. 7 is that the B-B of Fig. 6 is to cut-open view.
Describe the utility model in detail below in conjunction with embodiment and accompanying drawing thereof;
See also shown in Figure 1ly, the utility model includes casing 1, is equiped with a circuit control panel 7 in this casing 1, this circuit control panel 7 be control of the present utility model partly, this is concrete structure separate case application partly, so repeat no more.
Be equiped with a pump 2 in the casing 1, this pump 2 adopts high-quality double end micropump, and this kind double end micropump one end is connected in bottle for handling liquid toilet or cosmetic substance or distilled water bottle, the other end is connected in a surge flask, make the double end micropump bleeding when carrying out imbibition, unlikely with in the soiling solution suction pump 2, can protect pump 2 effectively; Be provided with a vertical movement mechanism 3 in the casing 1, this vertical movement mechanism 3 is driven by motor 31, and is provided with a stop means in the upper end of vertical movement mechanism 3, and cleaning head 5 is connected in this vertical movement mechanism 3.The front end of casing 1 outside is provided with one and can carries ELISA Plate worktable 6 is arranged, the horicontal motion mechanism 4 that worktable 6 is provided with, and this horicontal motion mechanism 4 is driven by a motor 43, and an end of this horicontal motion mechanism 4 is provided with a stop means; Cleaning head 5 is provided with two row's pins, and a row is water injection needle 52 for suction pin 51, one rows.
See also Fig. 2 and shown in Figure 3, vertical movement mechanism 3 comprises that one is fixed in the support 32 of casing 1, and motor 31 is fixed at the lower end of support 32, and motor 31 adopts stepper motor, and the output terminal of this motor 31 is connected with the screw thread elevating mechanism.The screw thread elevating mechanism is made of screw rod 33 that is connected in motor 31 output terminals and the nut 34 that matches with it, the cleaning head carriage 53 that is connected on this nut 34, and described cleaning head 5 can be plugged in the external part 531 of this cleaning head carriage 53; Be positioned on the support 32 of 33 sections of screw rods and be symmetrically arranged with two closed slides 35,36, cleaning head carriage 53 and 35,36 of two closed slides are folded with rolling body, to reduce cleaning head carriage 53 resistances of motion, can strengthen simultaneously the support width of cleaning head carriage 53, in the present embodiment, with set firmly spring leaf 37 corresponding to guide rail 35,36 places on the nut 34, this spring leaf 37 is provided with trundle 38 as above-mentioned rolling body, along guide rail 35,36 rectilinear motions.
See also Fig. 4 and shown in Figure 5, the horicontal motion mechanism 4 in the utility model is made of a guide piece 41 and actuator 42.In the present embodiment, described guide piece 41 can be two horizontally disposed feed rods 411,42, and this feed rod 411,412 is fixed in the casing 1 and the two ends of the support 45 that is connected with casing 1, and its stage casing is arranged in worktable 6; This worktable 6 is made of carriage 61 and objective table 62, and above-mentioned feed rod 411,412 is arranged on the carriage 61 of worktable 6; Actuator 42 include one be fixed in worktable 6 carriages 61 cog belt 421, an end of this cog belt 421 is provided with a belt pulley 422 that is connected in motor 43 output terminals, the other end is connected in the passive belt wheel 423 on the support 45.Along with the rotation of motor 43, worktable 6 drags lower edge two feed rods, 411,412 tangential movements cog belt 421.
See also Fig. 6 and the second kind of embodiment that goes out the utility model horicontal motion mechanism shown in Figure 7, in the present embodiment, guide piece 41 can be two horizontally disposed dovetail grooves 413, and the dove-tail form 414 that is complementary with this dovetail groove 413 is arranged in worktable carriage 61 bottoms; Screw rod 425 that its actuator 42 is connected by motor 41 output terminals and the nut 424 that is fixed on worktable carriage 61 constitute.
In the utility model, water injection needle on the cleaning head 5 51 and suction pin 52 disposes in pairs, can stretch into simultaneously in the same ELISA Plate hole, and water injection needle 51 slightly are shorter than suction pin 52, to prevent the excessive and mutual pollution of generation of reservoir quantity.And be provided with two holes in cleaning head 5, be connected to bottle for handling liquid toilet or cosmetic substance and waste liquid bottle through fluid injection flexible pipe and waste liquid flexible pipe.
The stop means of vertical movement mechanism is made of with the optocoupler bent plate 322 that is connected on the nut 34 optocoupler 321 that is arranged on the support 32, optocoupler bent plate 322 rises to nut 34 and opens the beginning during position, this optocoupler bent plate 322 inserts in the notch of optocoupler 321, send an electric signal, the motor 31 that drive screw rod 33 is enclosed stops operating, and reaches spacing purpose.
The stop means of horicontal motion mechanism 4 is made of with the optocoupler bent plate 452 that is connected on the worktable carriage 61 optocoupler 451 of the rightmost side of the support 45 that is arranged at horicontal motion mechanism 4, and its principle of work is identical with stop means in the vertical movement mechanism 3.The stop means of horicontal motion mechanism 4 is arranged at the top that opens of tangential movement.
Principle of work of the present utility model is, the user also is placed in the ELISA Plate of desire chemical examination on the objective table 62 of worktable 6 earlier, utilize control system setting cleaning way and send clear instruction, at first horicontal motion mechanism 4 drags worktable 6 from opening the beginning position to the working position, stepper motor 31 forwards in the vertical movement mechanism 3 start, and the screw rod 33 that drives its output terminal rotates, being bolted in nut 34 on the screw rod 33 drives the cleaning head carriage 53 that is connected thereon and stops after the aspirating needle 51 that opens the beginning position and vertically be displaced downwardly to cleaning head 5 arrives bottom, ELISA Plate holes, the beginning position of opening of horicontal motion mechanism 4 and vertical movement mechanism 3 is to be determined by stop means, and its stroke is to realize accurate localization by stepper motor 43 and 31 step numbers by calculated step; At this moment, double end micropump 2 controlled generation negative pressure, and by the aspirating needle on the cleaning head 5 51 waste liquid is sucked in the waste liquid bottle; Double end micropump 2 produces malleation again, extrude the washing lotion in the bottle for handling liquid toilet or cosmetic substance, by the fluid injection pin 52 on the cleaning head 5 washing lotion is injected in the respective aperture, fluid injection face rising while vertical movement mechanism 3 rises to thereupon and opens the beginning position, finishes cleaning the first time of ELISA Plate first round; And then drag worktable 6 by horicontal motion mechanism 4 and move to next working position exactly, repeat above-mentioned imbibition and fluid injection work, cleaned until the whole holes that will clean by instruction.After cleaning end for the first time, horicontal motion mechanism 4 is dragged to worktable and opens the beginning position, soaks, and soak time arrives, and the utility model then repeats primary cleaning by instruction ..., finish whole clear instructions until at last, and return and open the beginning position.Above-mentioned motion side and reservoir quantity carry out by the control system instruction automatically according to the requirement of user's cleaning way fully, can carry out single row of holes or the cleaning and the various plate mode of washing of round arbitrarily.
After all cleaning was finished, the user can change the bottle for handling liquid toilet or cosmetic substance that is connected in double end micropump 2 into distilled water bottle, carries out cleaning procedure, and the washing lotion in the pipeline is cleaned up, and prevents washing lotion to corrosion of pipe, can reduce the failure rate on liquid road effectively.
Claims (10)
1, a kind of automatic ELIAS microplate washer, include casing, be equiped with an appliance controling plate and pump in this casing, also include a vertical movement mechanism that drags by motor, this vertical movement mechanism is provided with stop means, and cleaning head is connected in this vertical movement mechanism, and the front end of casing is provided with one can carry the worktable of ELISA Plate, it is characterized in that described worktable is provided with a horicontal motion mechanism that is dragged by motor, an end of this horicontal motion mechanism is provided with a stop means; The stop means of vertical movement mechanism then is arranged at the upper end of this vertical movement mechanism; Described cleaning head is provided with row's suction pin and row's water injection needle.
2, according to a kind of automatic ELIAS microplate washer of claim 1, it is characterized in that described vertical movement mechanism comprises that one is fixed in the support of casing, set firmly a motor on the support, the output terminal of this motor is connected with the screw thread elevating mechanism.
3, according to a kind of automatic ELIAS microplate washer of claim 2, it is characterized in that described screw thread elevating mechanism reaches the nut that matches with it by the screw rod that is connected in motor output end and constitutes, a cleaning head carriage is connected on this nut, described cleaning head can be plugged in the external part of this cleaning head carriage, be positioned on the support of thread segment and be symmetrically arranged with guide rail, be folded with rolling body between cleaning head and guide rail.
4,, it is characterized in that described horicontal motion mechanism is made of a guide piece and an actuator according to a kind of automatic ELIAS microplate washer of claim 1.
5, according to a kind of automatic ELIAS microplate washer of claim 4, it is characterized in that described guide piece can be two horizontally disposed feed rods, this feed rod is arranged in worktable; Its actuator includes the cog belt that is fixed in worktable, and an end of this cog belt is provided with a belt pulley that is connected in motor output end, and the other end is connected in the passive belt wheel that is fixed on the casing.
6, according to a kind of automatic ELIAS microplate washer of claim 4, it is characterized in that described guide piece can be two horizontally disposed dovetail grooves, the dove-tail form that is complementary with this dovetail groove is arranged in worktable carriage bottom; Screw rod that its actuator is connected by motor output end and the nut that is fixed on the worktable carriage constitute.
7,, it is characterized in that the water injection needle on the described cleaning head is shorter than the suction pin according to a kind of automatic ELIAS microplate washer of claim 1.
8, according to a kind of automatic ELIAS microplate washer of claim 1, it is characterized in that described pump can be the double end micropump, this double end micropump is connected in surge flask and bottle for handling liquid toilet or cosmetic substance.
9,, it is characterized in that the stop means of described vertical movement mechanism is made of with the optocoupler bent plate that is connected on the nut the photoelectric coupled circuit that is arranged on the support according to a kind of automatic ELIAS microplate washer of claim 1.
10,, it is characterized in that the stop means of described horicontal motion mechanism is made of with the optocoupler bent plate that is connected on the worktable carriage the optocoupler that is arranged on the casing according to a kind of automatic ELIAS microplate washer of claim 1.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN 96207598 CN2276635Y (en) | 1996-04-11 | 1996-04-11 | Automatic enzyme labelling board washing machine |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN 96207598 CN2276635Y (en) | 1996-04-11 | 1996-04-11 | Automatic enzyme labelling board washing machine |
Publications (1)
Publication Number | Publication Date |
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CN2276635Y true CN2276635Y (en) | 1998-03-18 |
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ID=33891855
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN 96207598 Expired - Fee Related CN2276635Y (en) | 1996-04-11 | 1996-04-11 | Automatic enzyme labelling board washing machine |
Country Status (1)
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CN (1) | CN2276635Y (en) |
Cited By (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102527655A (en) * | 2011-12-30 | 2012-07-04 | 洛阳理工学院 | Turnover vertical washing machine for microplates |
CN102632046A (en) * | 2012-04-13 | 2012-08-15 | 华南理工大学 | Improved environmental-friendly high-efficiency fully automatic plate washing machine movement device |
CN103163096A (en) * | 2013-03-22 | 2013-06-19 | 山东博科生物产业有限公司 | Full-automatic multi-channel absorbance measuring instrument |
CN103658087A (en) * | 2013-12-06 | 2014-03-26 | 桂林电子科技大学 | Full-automatic efficient horizontal type enzyme-linked immunosorbent assay plate washing machine |
CN103675265A (en) * | 2013-12-20 | 2014-03-26 | 江苏金太生命科技有限公司 | Elisa plate shelf applicable to microplate reader |
CN106140754A (en) * | 2016-07-28 | 2016-11-23 | 盐城拜明生物技术有限公司 | cleaning equipment suitable for immunoassay instrument |
CN106513362A (en) * | 2016-11-07 | 2017-03-22 | 百奥森(江苏)食品安全科技有限公司 | Simple energy-saving enzyme labeling plate washing machine |
CN106733807A (en) * | 2016-12-07 | 2017-05-31 | 无锡艾科瑞思产品设计与研究有限公司 | A kind of new automatic enzyme non-analysis meter board-washing machine leak-proof device |
-
1996
- 1996-04-11 CN CN 96207598 patent/CN2276635Y/en not_active Expired - Fee Related
Cited By (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102527655A (en) * | 2011-12-30 | 2012-07-04 | 洛阳理工学院 | Turnover vertical washing machine for microplates |
CN102632046A (en) * | 2012-04-13 | 2012-08-15 | 华南理工大学 | Improved environmental-friendly high-efficiency fully automatic plate washing machine movement device |
CN103163096A (en) * | 2013-03-22 | 2013-06-19 | 山东博科生物产业有限公司 | Full-automatic multi-channel absorbance measuring instrument |
CN103163096B (en) * | 2013-03-22 | 2015-05-20 | 山东博科生物产业有限公司 | Full-automatic multi-channel absorbance measuring instrument |
CN103658087A (en) * | 2013-12-06 | 2014-03-26 | 桂林电子科技大学 | Full-automatic efficient horizontal type enzyme-linked immunosorbent assay plate washing machine |
CN103658087B (en) * | 2013-12-06 | 2016-05-04 | 桂林电子科技大学 | The horizontal plate machine of washing of full automatic high efficiency enzyme mark |
CN103675265A (en) * | 2013-12-20 | 2014-03-26 | 江苏金太生命科技有限公司 | Elisa plate shelf applicable to microplate reader |
CN103675265B (en) * | 2013-12-20 | 2015-06-03 | 江苏金太生命科技有限公司 | Elisa plate shelf applicable to microplate reader |
CN106140754A (en) * | 2016-07-28 | 2016-11-23 | 盐城拜明生物技术有限公司 | cleaning equipment suitable for immunoassay instrument |
CN106140754B (en) * | 2016-07-28 | 2019-04-09 | 江苏拜明生物技术有限公司 | Cleaning equipment suitable for immunoassay instrument |
CN106513362A (en) * | 2016-11-07 | 2017-03-22 | 百奥森(江苏)食品安全科技有限公司 | Simple energy-saving enzyme labeling plate washing machine |
CN106733807A (en) * | 2016-12-07 | 2017-05-31 | 无锡艾科瑞思产品设计与研究有限公司 | A kind of new automatic enzyme non-analysis meter board-washing machine leak-proof device |
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C14 | Grant of patent or utility model | ||
GR01 | Patent grant | ||
C19 | Lapse of patent right due to non-payment of the annual fee | ||
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