CN221028468U - A edulcoration equipment after being used for enzymolysis of mucosa liquid of heparin sodium crude preparation - Google Patents
A edulcoration equipment after being used for enzymolysis of mucosa liquid of heparin sodium crude preparation Download PDFInfo
- Publication number
- CN221028468U CN221028468U CN202322713565.1U CN202322713565U CN221028468U CN 221028468 U CN221028468 U CN 221028468U CN 202322713565 U CN202322713565 U CN 202322713565U CN 221028468 U CN221028468 U CN 221028468U
- Authority
- CN
- China
- Prior art keywords
- filter screen
- enzymolysis
- tank body
- screen body
- threaded rod
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Links
- 239000007788 liquid Substances 0.000 title claims abstract description 16
- 229920000669 heparin Polymers 0.000 title claims abstract description 15
- ZFGMDIBRIDKWMY-PASTXAENSA-N heparin Chemical compound CC(O)=N[C@@H]1[C@@H](O)[C@H](O)[C@@H](COS(O)(=O)=O)O[C@@H]1O[C@@H]1[C@@H](C(O)=O)O[C@@H](O[C@H]2[C@@H]([C@@H](OS(O)(=O)=O)[C@@H](O[C@@H]3[C@@H](OC(O)[C@H](OS(O)(=O)=O)[C@H]3O)C(O)=O)O[C@@H]2O)CS(O)(=O)=O)[C@H](O)[C@H]1O ZFGMDIBRIDKWMY-PASTXAENSA-N 0.000 title claims abstract description 15
- 229960001008 heparin sodium Drugs 0.000 title claims abstract description 15
- 210000004877 mucosa Anatomy 0.000 title claims abstract description 9
- 238000002360 preparation method Methods 0.000 title claims description 3
- 239000012535 impurity Substances 0.000 claims abstract description 46
- 230000007246 mechanism Effects 0.000 claims abstract description 31
- 238000007790 scraping Methods 0.000 claims abstract description 30
- 239000000463 material Substances 0.000 claims abstract description 8
- 239000012530 fluid Substances 0.000 claims description 6
- 238000006047 enzymatic hydrolysis reaction Methods 0.000 claims 4
- 238000004140 cleaning Methods 0.000 abstract description 8
- 210000004400 mucous membrane Anatomy 0.000 abstract description 8
- 238000000034 method Methods 0.000 abstract description 7
- 238000012423 maintenance Methods 0.000 abstract description 5
- 230000008569 process Effects 0.000 abstract description 5
- 230000000903 blocking effect Effects 0.000 abstract description 3
- 230000000694 effects Effects 0.000 description 10
- 230000009471 action Effects 0.000 description 2
- 239000000428 dust Substances 0.000 description 2
- 238000003756 stirring Methods 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000002210 biocatalytic effect Effects 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 230000032050 esterification Effects 0.000 description 1
- 238000005886 esterification reaction Methods 0.000 description 1
- 230000002349 favourable effect Effects 0.000 description 1
- 238000010030 laminating Methods 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 210000004379 membrane Anatomy 0.000 description 1
- 239000012528 membrane Substances 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 239000013049 sediment Substances 0.000 description 1
Classifications
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/10—Process efficiency
Landscapes
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Abstract
The utility model discloses a device for removing impurities after enzymolysis of a mucous membrane liquid for preparing a crude heparin sodium product, which comprises an enzymolysis tank body, a scraping mechanism and an impurity collecting mechanism, wherein a filter screen body is connected in the enzymolysis tank body, holes are drilled on the filter screen body, a material leakage port is connected at the lower end of the enzymolysis tank body, the scraping mechanism is connected in the enzymolysis tank body, the scraping mechanism comprises a scraping plate, a threaded rod is connected in the enzymolysis tank body, the threaded rod penetrates through the scraping plate, a sliding rod is connected to the filter screen body, and the sliding rod penetrates through the scraping plate. According to the utility model, through the arrangement of the corresponding mechanism on the mucosa liquid enzymolysis impurity removal device, after the mucosa liquid is subjected to enzymolysis, the filter screen in the tank body can be cleaned, so that impurities which are remained on the filter screen and cannot be decomposed can be cleaned in the enzymolysis process, the probability of blocking the filter screen is reduced, the later cleaning and maintenance work is more convenient, and the working flow is not influenced.
Description
Technical Field
The utility model belongs to the technical field of mucosal fluid enzymolysis, and particularly relates to a device for removing impurities after enzymolysis of a mucosal fluid for preparing a crude heparin sodium product.
Background
An enzymolysis tank is an industrial device commonly used in biocatalytic processes, such as enzymolysis, esterification, saccharification, etc., and some residues, sediments or biological membranes may accumulate in the enzymolysis tank, so that cleaning and maintenance are required periodically to ensure the performance of the device and the stability of the production process.
At present, after enzymolysis is carried out on mucous membrane liquid, insoluble impurities can be accumulated in the tank body, and a mechanism for cleaning the impurities which are not accumulated in the tank body is not available in the prior art, so that in the enzymolysis process, a part of materials cannot be decomposed, and the materials can be remained on the filter screen for a long time, so that the filter is blocked, the later cleaning and maintenance work is inconvenient, and the workflow is affected to a certain extent.
Therefore, aiming at the technical problems, it is necessary to provide a device for removing impurities after enzymolysis of a mucous membrane liquid for preparing a crude heparin sodium product.
Disclosure of utility model
The utility model aims to provide a device for removing impurities after enzymolysis of a mucous membrane liquid prepared from a crude heparin sodium product, so as to solve the problem that a mechanism for cleaning impurities which are not accumulated in a tank body is not provided.
In order to achieve the above object, an embodiment of the present utility model provides the following technical solution:
the equipment for removing impurities after enzymolysis of the mucous membrane liquid prepared from the crude heparin sodium comprises an enzymolysis tank body, a scraping mechanism and an impurity collecting mechanism;
The scraping mechanism is connected in the enzymolysis tank body, the scraping mechanism comprises a scraping plate, a threaded rod is connected in the enzymolysis tank body, the threaded rod penetrates through the scraping plate, a sliding rod is connected to the filter screen body, and the sliding rod penetrates through the scraping plate;
The impurity collecting mechanism is connected under the filter screen body.
Further, be connected with the motor under the filter screen body, the motor runs through the filter screen body is connected with the threaded rod, has played the effect of power, has made things convenient for the drive threaded rod to carry out pivoted effect to the scraper blade of being convenient for reciprocates according to the rotation of threaded rod.
Further, be connected with the bearing on the filter screen body, the threaded rod is observed the bearing sets up, has made things convenient for the connection of threaded rod, makes the threaded rod through the effect of bearing can reduce the frictional force of threaded rod to the filter screen body when carrying out the pivoted.
Further, the material leakage opening penetrates through the impurity collecting mechanism, and the impurity collecting mechanism comprises a collecting bin, so that the effect of accumulating the scraped impurities on the filter screen body is facilitated;
The collecting bin is provided with the collecting opening, so that the falling impurities can conveniently fall into the collecting bin through the collecting opening when the scraping plate scrapes the filter screen body;
The filter screen body has the baffle frame down, baffle frame and hole assorted, the motor runs through baffle frame is set up, and the baffle frame can be plugged up the hole in order to leak protection to the effect on the impurity collection mechanism when enzymolysis tank body carries out enzymolysis stirring, simultaneously when striking off the filter screen body through electric telescopic handle's cooperation open the baffle frame can make things convenient for dropping of impurity.
Further, be connected with a plurality of electric telescopic links between baffle frame and the collection storehouse, can separate baffle frame and hole when electric telescopic link contracts to be favorable to dropping of impurity dust, alright plug up the hole with the baffle frame when electric telescopic link extends.
Compared with the prior art, the utility model has the following advantages:
According to the utility model, through the arrangement of the corresponding mechanism on the mucosa liquid enzymolysis impurity removal device, after the mucosa liquid is subjected to enzymolysis, the filter screen in the tank body can be cleaned, so that impurities which are remained on the filter screen and cannot be decomposed can be cleaned in the enzymolysis process, the probability of blocking the filter screen is reduced, the later cleaning and maintenance work is more convenient, and the working flow is not influenced.
Drawings
In order to more clearly illustrate the embodiments of the present utility model or the technical solutions in the prior art, the drawings that are required to be used in the embodiments or the description of the prior art will be briefly described below, and it is obvious that the drawings in the following description are only some embodiments described in the present utility model, and other drawings may be obtained according to the drawings without inventive effort to those skilled in the art.
FIG. 1 is a cross-sectional view of a device for removing impurities after enzymolysis of a mucous membrane solution for preparing a crude heparin sodium product in an embodiment of the utility model;
FIG. 2 is a schematic diagram of the structure of FIG. 1 at A;
Fig. 3 is a perspective view of a device for removing impurities after enzymolysis of a mucous membrane solution for preparing a crude heparin sodium product in an embodiment of the utility model.
In the figure: 1. the enzymolysis tank comprises an enzymolysis tank body, 101, a filter screen body, 102, a material leakage port, 2, a scraping mechanism, 201, a scraping plate, 202, a threaded rod, 203, a sliding rod, 204, a motor, 205, a bearing, 3, a foreign matter collecting mechanism, 301, a collecting bin, 302, a collecting port, 303, a baffle frame and 304, and an electric telescopic rod.
Detailed Description
The present utility model will be described in detail below with reference to the embodiments shown in the drawings. The embodiments are not intended to limit the utility model, but structural, methodological or functional modifications from the embodiments are within the scope of the utility model.
The utility model discloses a device for removing impurities after enzymolysis of a mucous membrane liquid for preparing a crude heparin sodium product, which is shown in fig. 1-3 and comprises an enzymolysis tank body 1, a scraping mechanism 2 and an impurity collecting mechanism 3.
Referring to fig. 1-3, the scraping mechanism 2 is connected in the enzymolysis tank body 1, and the scraping mechanism 2 comprises a scraping plate 201, so that the scraping effect on insoluble impurities on the filter screen body 101 is facilitated.
Wherein, enzymolysis tank body 1 internal connection has threaded rod 202, and threaded rod 202 runs through the setting of striking off plate 201, has made things convenient for when threaded rod 202 rotates can drive the effect that striking off plate 201 carried out the downwardly moving to strike off the impurity on the filter screen body 101.
In other words, the filter screen body 101 is connected with the sliding rod 203, and the sliding rod 203 penetrates through the scraping plate 201, so as to assist the scraping plate 201 to slide up and down, and improve the sliding stability of the scraping plate 201.
Referring to fig. 1-3, a motor 204 is connected under the filter screen body 101, and the motor 204 penetrates through the filter screen body 101 and is connected with the threaded rod 202, so that the action of power is achieved, the threaded rod 202 is conveniently driven to rotate, and the scraping plate 201 is conveniently moved up and down according to the rotation of the threaded rod 202.
Referring to fig. 1-3, the filter screen body 101 is connected with a bearing 205, and the threaded rod 202 is arranged by observing the bearing 205, so that the threaded rod 202 is convenient to connect, and the friction force of the threaded rod 202 to the filter screen body 101 can be reduced by the action of the bearing 205 when the threaded rod 202 rotates.
Referring to fig. 2-3, the material leakage opening 102 is provided through the impurity collecting mechanism 3, and the impurity collecting mechanism 3 includes a collecting bin 301, which facilitates the effect of accumulating the scraped impurities on the filter screen body 101.
Wherein, the collection bin 301 is cut with a collection opening 302, so that the falling impurities can fall into the collection bin 301 through the collection opening 302 when the scraping plate 201 scrapes the filter screen body 101.
In addition, filter screen body 101 has baffle frame 303 down, baffle frame 303 and hole assorted, and motor 204 runs through baffle frame 303 setting, and the baffle frame 303 can plug up the hole in order to leak protection to the effect on the impurity collection mechanism 3 when enzymolysis tank body 1 stirs, simultaneously when striking off filter screen body 101 through the cooperation of electric telescopic handle 304 open baffle frame 303 can make things convenient for dropping of impurity.
Referring to fig. 2-3, a plurality of electric telescopic rods 304 are connected between the baffle plate frame 303 and the collecting bin 301, and when the electric telescopic rods 304 are contracted, the baffle plate frame 303 and the holes can be separated, so that the falling of impurity dust is facilitated, and when the electric telescopic rods 304 are extended, the baffle plate frame 303 can be blocked in the holes.
Specifically, when cleaning filter screen body 101, make and be in under the circumstances that does not have liquid in the enzymolysis tank body 1 clear up, start motor 204 rotates just can drive threaded rod 202 and rotate, and strike off the board 201 on the threaded rod 202 just can carry out the downwardly moving according to the rotation of threaded rod 202, the effect that improves stability can be played to slide bar 203 when the removal, strike off the in-process that board 201 moved downwardly, strike off the board 201 laminating filter screen body 101 alright scrape the impurity on the filter screen body 101, start electric telescopic handle 304 shrink at this moment and just can drive baffle frame 303 downwardly moving, the in-process baffle frame 303 of removal just can separate with the hole, thereby the impurity sideboard that is scraped off drops in the middle of collecting bin 301 through the hole, can open the bottom of enzymolysis tank body 1 when clearing up collecting bin 301 and get rid of clearance.
The technical scheme shows that the utility model has the following beneficial effects:
According to the utility model, through the arrangement of the corresponding mechanism on the mucosa liquid enzymolysis impurity removal device, after the mucosa liquid is subjected to enzymolysis, the filter screen in the tank body can be cleaned, so that impurities which are remained on the filter screen and cannot be decomposed can be cleaned in the enzymolysis process, the probability of blocking the filter screen is reduced, the later cleaning and maintenance work is more convenient, and the working flow is not influenced.
It will be evident to those skilled in the art that the utility model is not limited to the details of the foregoing illustrative embodiments, and that the present utility model may be embodied in other specific forms without departing from the spirit or essential characteristics thereof. The present embodiments are, therefore, to be considered in all respects as illustrative and not restrictive, the scope of the utility model being indicated by the appended claims rather than by the foregoing description, and all changes which come within the meaning and range of equivalency of the claims are therefore intended to be embraced therein. Any reference sign in a claim should not be construed as limiting the claim concerned.
Furthermore, it should be understood that although the present disclosure describes embodiments, not every embodiment contains only one independent technical solution, and that such description is provided for clarity only, and that the technical solutions of the embodiments may be appropriately combined to form other embodiments that will be understood by those skilled in the art.
Claims (5)
1. A remove miscellaneous equipment after being used for mucosa liquid enzymolysis of heparin sodium crude preparation, its characterized in that includes:
The enzymolysis tank comprises an enzymolysis tank body (1), wherein a filter screen body (101) is connected in the enzymolysis tank body (1), holes are cut on the filter screen body (101), and a material leakage opening (102) is connected at the lower end of the enzymolysis tank body (1);
The scraping mechanism (2) is connected in the enzymolysis tank body (1), the scraping mechanism (2) comprises a scraping plate (201), a threaded rod (202) is connected in the enzymolysis tank body (1), the threaded rod (202) penetrates through the scraping plate (201), a sliding rod (203) is connected on the filter screen body (101), and the sliding rod (203) penetrates through the scraping plate (201);
Impurity collection mechanism (3) is connected under filter screen body (101).
2. The post-enzymatic hydrolysis mucosal-fluid impurity removing device for preparing a crude heparin sodium product according to claim 1, wherein a motor (204) is connected below the filter screen body (101), and the motor (204) penetrates through the filter screen body (101) and is connected with a threaded rod (202).
3. The post-enzymatic hydrolysis mucosal-fluid impurity removing device for preparing a crude heparin sodium product according to claim 2, wherein a bearing (205) is connected to the filter screen body (101), and the threaded rod (202) is used for observing the arrangement of the bearing (205).
4. The post-enzymatic hydrolysis mucosal-fluid impurity removing device for preparing a crude heparin sodium product according to claim 2, wherein the material leakage opening (102) penetrates through the impurity collecting mechanism (3), the impurity collecting mechanism (3) comprises a collecting bin (301), a collecting opening (302) is cut on the collecting bin (301), a baffle frame (303) is arranged below the filter screen body (101), the baffle frame (303) is matched with a hole, and the motor (204) penetrates through the baffle frame (303).
5. The post-enzymatic hydrolysis mucosal-fluid impurity removing device for preparing a crude heparin sodium product according to claim 4, wherein a plurality of electric telescopic rods (304) are connected between the baffle frame (303) and the collecting bin (301).
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN202322713565.1U CN221028468U (en) | 2023-10-10 | 2023-10-10 | A edulcoration equipment after being used for enzymolysis of mucosa liquid of heparin sodium crude preparation |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN202322713565.1U CN221028468U (en) | 2023-10-10 | 2023-10-10 | A edulcoration equipment after being used for enzymolysis of mucosa liquid of heparin sodium crude preparation |
Publications (1)
Publication Number | Publication Date |
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CN221028468U true CN221028468U (en) | 2024-05-28 |
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ID=91182888
Family Applications (1)
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CN202322713565.1U Active CN221028468U (en) | 2023-10-10 | 2023-10-10 | A edulcoration equipment after being used for enzymolysis of mucosa liquid of heparin sodium crude preparation |
Country Status (1)
Country | Link |
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CN (1) | CN221028468U (en) |
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2023
- 2023-10-10 CN CN202322713565.1U patent/CN221028468U/en active Active
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