CN220999638U - Top core thorn membrane pipetting system - Google Patents
Top core thorn membrane pipetting system Download PDFInfo
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- CN220999638U CN220999638U CN202322808384.7U CN202322808384U CN220999638U CN 220999638 U CN220999638 U CN 220999638U CN 202322808384 U CN202322808384 U CN 202322808384U CN 220999638 U CN220999638 U CN 220999638U
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- core
- film
- packaging tube
- sealing
- mixing chamber
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- 239000012528 membrane Substances 0.000 title claims abstract description 18
- 238000007789 sealing Methods 0.000 claims abstract description 71
- 238000004806 packaging method and process Methods 0.000 claims abstract description 56
- 238000002156 mixing Methods 0.000 claims abstract description 46
- 239000007788 liquid Substances 0.000 claims abstract description 26
- 238000003756 stirring Methods 0.000 claims abstract description 22
- 230000000694 effects Effects 0.000 claims abstract description 8
- 230000003014 reinforcing effect Effects 0.000 claims description 5
- 238000000605 extraction Methods 0.000 abstract description 5
- 238000000034 method Methods 0.000 abstract description 4
- 230000008569 process Effects 0.000 abstract description 4
- 238000000746 purification Methods 0.000 abstract description 3
- 238000004080 punching Methods 0.000 abstract 1
- 102000039446 nucleic acids Human genes 0.000 description 7
- 108020004707 nucleic acids Proteins 0.000 description 7
- 150000007523 nucleic acids Chemical class 0.000 description 7
- 238000003780 insertion Methods 0.000 description 5
- 230000037431 insertion Effects 0.000 description 5
- 238000012546 transfer Methods 0.000 description 4
- 238000011160 research Methods 0.000 description 3
- 238000010586 diagram Methods 0.000 description 2
- 230000000149 penetrating effect Effects 0.000 description 2
- 238000000926 separation method Methods 0.000 description 2
- 208000005623 Carcinogenesis Diseases 0.000 description 1
- 208000026350 Inborn Genetic disease Diseases 0.000 description 1
- 208000019155 Radiation injury Diseases 0.000 description 1
- 230000002159 abnormal effect Effects 0.000 description 1
- 239000012445 acidic reagent Substances 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 230000000712 assembly Effects 0.000 description 1
- 238000000429 assembly Methods 0.000 description 1
- 230000036952 cancer formation Effects 0.000 description 1
- 231100000504 carcinogenesis Toxicity 0.000 description 1
- 239000003153 chemical reaction reagent Substances 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 239000011888 foil Substances 0.000 description 1
- 230000014509 gene expression Effects 0.000 description 1
- 208000016361 genetic disease Diseases 0.000 description 1
- 230000002068 genetic effect Effects 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012856 packing Methods 0.000 description 1
- 239000002985 plastic film Substances 0.000 description 1
- 229920006255 plastic film Polymers 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 125000003003 spiro group Chemical group 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
Landscapes
- Sampling And Sample Adjustment (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
Abstract
A top-core prick film pipetting system comprises a mixing chamber, a packaging tube and a top-core device. The packaging tube comprises a packaging tube main body, a packaging tube opening, an inserting tube and a packaging liquid film. The core jacking device comprises a driving rod and a film punching piece. The driving rod sequentially comprises a driving section, a sealing section, a connecting section and a sealing ring. The film piercing member comprises a stirring wheel and a film piercing member. The length of the top core device is larger than the sum of the heights of the packaging tube and the mixing chamber, so that the top core device is conveniently inserted into the bottom of the mixing chamber to fully mix the liquid. The core-pushing film-puncturing liquid transferring system punctures a liquid sealing film on the packaging tube through the core-pushing device, and transmits a sample to the mixing chamber to fulfill the aim of uniformly stirring. The top core thorn membrane pipetting system is simple in structure and convenient to use, ensures the tightness of the sample transferring process and the mixing efficiency of the liquid sample, and improves the sample extraction and purification effect and accuracy.
Description
Technical Field
The utility model belongs to the technical field of medical instruments, and particularly relates to a top core thorn film pipetting system.
Background
Nucleic acid is taken as a carrier of genetic information, is a material basis of gene expression, has important roles in normal growth, development, reproduction and other life activities of organisms, and has close relation with abnormal situations of life, such as tumorigenesis, radiation injury, genetic diseases and the like. Therefore, the separation and purification of nucleic acid is a very important link in molecular biology and medical research. In addition, the separation and purification of proteins are also important steps in sample pretreatment in modern biomedical research.
The nucleic acid reagent automatically completes the extraction of the sample nucleic acid by a nucleic acid extractor, wherein the nucleic acid is contained in a test tube for detection. At present, a sealing film made of plastic film or metal foil is arranged at an opening of a packaging tube to play a role in sealing, and the sealing film is pierced through a piercing film piece in the process of extracting and detecting nucleic acid, so that a sample in the packaging tube is transferred into a mixing chamber, but the liquid mixing efficiency is poor, and the sample extracting effect is not facilitated.
Disclosure of utility model
In view of the above, the present utility model provides a top-core piercing film pipetting system for improving sample extraction effect to meet the needs of industrial and medical research.
A top core prick film pipetting system comprises a mixing chamber for containing a sample, a packaging tube arranged on the mixing chamber, and a top core device inserted on the packaging tube. The packaging tube comprises a packaging tube main body, a packaging tube opening arranged at one end of the packaging tube main body, a plug-in tube arranged at one end of the packaging tube main body opposite to the opening of the packaging tube, and a liquid sealing film arranged on the opening of the packaging tube. The core jacking device comprises a driving rod inserted into the insertion pipe and a film piercing member arranged at one end of the driving rod and accommodated in the packaging pipe main body. The driving rod sequentially comprises a driving section, a sealing section, a connecting section and at least one sealing ring sleeved on the sealing section. The film piercing member comprises a stirring wheel arranged at one end of the connecting section and a film piercing member arranged at one side of the stirring wheel facing the mixing chamber. The length of the core jacking device is greater than the sum of the heights of the packaging tube and the mixing chamber, so that the core jacking device is conveniently inserted into the mixing chamber, and the mixing effect is improved.
Further, the sealing tube main body is close to the outer wall of one end of the opening of the sealing tube, and is provided with a liquid leakage preventing device which is tightly connected with the mixing chamber and is provided with a leakage preventing external thread.
Further, the seal segment comprises a seal segment body, and at least one accommodating groove is formed in the seal segment body.
Further, the core jacking device further comprises a limiting section arranged at one end of the connecting section, which faces the sealing section, and the diameter of the limiting section is larger than the inner diameter of the plug-in pipe.
Further, the film-piercing member further comprises at least one reinforcing rib arranged between the stirring wheel and the film-piercing member.
Further, the film piercing member is obliquely arranged towards one side edge of the mixing chamber.
Compared with the prior art, the core-pushing film-puncturing pipetting system provided by the utility model punctures the sealing liquid film on the packaging tube through the core pushing device and uniformly stirs and transmits the sample into the mixing chamber. The core jacking device comprises a driving rod inserted into the insertion pipe and a film piercing member arranged at one end of the driving rod. The driving rod in the core jacking device is inserted into the insertion tube of the packaging tube, and comprises a driving section, a sealing section, a connecting section and at least one sealing ring sleeved on the sealing section in sequence. The sealing ring is arranged on the sealing section, and the sealing section is accommodated in the plug-in pipe so as to ensure the tightness between the core jacking device and the sealing pipe. In addition, the length of the core jacking device is larger than the sum of the heights of the packaging tube and the mixing chamber, so that the core jacking device is conveniently inserted into the mixing chamber, and sample transfer between the packaging tube and the mixing chamber is realized. When the top core thorn membrane pipetting system is in use, the driving rod drives the thorn membrane piece to move to the liquid sealing membrane, the liquid sealing membrane is pierced, and the external equipment drives the driving rod to rotate, so that samples are uniformly stirred and transferred into the mixing chamber. Therefore, the top core thorn film pipetting system is simple in structure and convenient to use, ensures the tightness of the sample transferring process, and improves the sample extraction effect and accuracy.
Drawings
Fig. 1 is a schematic structural diagram of a top-core piercing film pipetting system provided by the utility model.
Fig. 2 is a schematic cross-sectional view of the top-core piercing film pipetting system of fig. 1.
Fig. 3 is a schematic structural view of a core ejection device in the core ejection film pipetting system of fig. 1.
Detailed Description
Specific embodiments of the present utility model are described in further detail below. It should be understood that the description herein of the embodiments of the utility model is not intended to limit the scope of the utility model.
Fig. 1 to 3 are schematic structural diagrams of a top-core piercing film pipetting system according to the present utility model. The core-spun-laced film pipetting system comprises a mixing chamber 1 for containing reagents, a packaging tube 10 screwed on the mixing chamber 1, and a core-spun device 20 inserted on the packaging tube 10. The top-core membrane pipetting system also comprises other functional modules, such as assemblies, which should be known to the person skilled in the art and will not be described in any detail here.
The mixing chamber 1 is used for connecting the packaging tube 10, the samples in the packaging tube 10 are concentrated in the mixing chamber 1, the mixing chamber 1 is provided with a mounting tube 2, wherein the mounting tube 2 is provided with internal threads, and the mounting tube 2 and the packaging tube 10 are mounted together. The mixing chamber 1 and the mounting tube 2 are all of a prior art and are not described in detail herein.
The packaging tube 10 comprises a packaging tube body 11, a packaging tube opening 12 arranged at one end of the packaging tube body 11, a plug tube 13 arranged at one end of the packaging tube body 11 facing away from the packaging tube opening 12, and a sealing liquid film 14 arranged on the packaging tube opening 12.
The utility model discloses a sealing tube, including sealing tube main part 11, sealing tube opening 12, sealing tube main part 11, sealing tube opening 12 is for sealing tube main part 11's sample access & exit realizes the transfer of sample in the sealing tube main part 11, the one end intercommunication of grafting tube 13 sealing tube main part 11's cavity, and with the other end intercommunication of grafting tube 13, just grafting tube 13 is used for installing top core device 20, so that top core device 20 is in sealing tube 10's position is stable, sealing tube main part 11 is close to sealing tube opening 12 one end outer wall is last to set up with mixing chamber 1 zonulae occludens's leak protection liquid device, in this embodiment, leak protection liquid device is leak protection external screw thread, sealing tube main part 11 through this leak protection external screw thread with install between the pipe 2 the spiro union together, thereby sealing tube 10 and mixing chamber 1 interconnect together. The plug tube 13 and the packaging tube main body 11 are integrally formed, and the central axis of the plug tube 13 and the central axis of the packaging tube main body 11 are coincident, so that when the core jacking device 20 is inserted into the plug tube 13, the central axes of the core jacking device 20 and the packaging tube main body 11 are also coincident, thereby facilitating the rotation of the core jacking device 20. The sealing tube body 11, the sealing tube opening 12, and the plugging tube 13 are all of a prior art, and will not be described in detail herein.
The sealing liquid film 14 is used for sealing the extracted sample in the main body 11 of the sealing tube, the sealing liquid film 14 is disposed in the opening 12 of the sealing tube, and the sealing liquid film 14 is a prior art and will not be described herein.
The core ejecting device 20 comprises a driving rod 21 inserted into the insertion tube 13, and a film penetrating member 22 disposed at one end of the driving rod 21 and accommodated in the packaging tube body 11.
The driving rod 21 sequentially comprises a driving section 211, a sealing section 212, a connecting section 213, at least one sealing ring 214 sleeved on the sealing section 212, and a limiting section 215 arranged at one end of the connecting section 213 facing the sealing section 212.
The driving section 211 is used for being connected with an external device, and the driving rod 21 is driven by the external device, so as to drive the driving rod 21 to move, and the driving section 211 is a positioning and rotating mechanism in the driving rod 21. The outer contour of the driving section 211 is any one of a hexagonal prism and a pentagonal prism, and in this embodiment, the outer contour of the driving section 211 is a hexagonal prism. The seal segment 212 and the connecting segment 213 are cylindrical and rotatable structures.
The seal segment 212 includes a seal segment body 2121 and at least one receiving groove 2122 provided on the seal segment body 2121. The accommodating groove 2122 is configured to accommodate the seal ring 214, so that the seal ring 214 is positioned on the driving rod 21 stably.
The connecting section 213 is used for connecting the film piercing member 22, so that the driving rod 21 can drive the film piercing member 22 to move. The driving section 211, the sealing section 212, the connecting section 213, and the film piercing member 22 are integrally formed, so that the core propping device 20 is structurally stable.
The seal ring 214 is used to improve the tightness of the seal section 212, and the seal ring 214 is a prior art and will not be described herein.
The diameter of the limiting section 215 is larger than the inner diameter of the plug tube 13, and the limiting section 215 limits the position of the core pushing device 20 in the plug tube 13.
The film-piercing member 22 comprises a stirring wheel 221 disposed at one end of the connecting section 213, a film-piercing member 222 disposed at a side of the stirring wheel 221 facing the mixing chamber 1, and at least one reinforcing rib 223 disposed between the stirring wheel 221 and the film-piercing member 222.
The agitator 221 includes a ring 2211 and three blades 2212 spaced between the driving rod 21 and the ring 2211. When the driving rod 21 rotates the stirring wheel 221, the sample in the packing tube 10 flows to the stirring wheel 221, and the blade 2212 stirs the sample to uniformly stir the sample.
The film piercing member 222 is disposed obliquely toward one side edge of the mixing chamber 1 so that the film piercing member 222 pierces the sealing film 14.
The reinforcing rib 223 is disposed between the stirring wheel 221 and the film-piercing member 222 to fix the position of the film-piercing member 222 on the stirring wheel 221, and the reinforcing rib 223 is a prior art and will not be described herein.
When the top core film-penetrating pipetting system is in use, an external device is connected with the driving rod 21 and drives the driving rod 21 to move, the driving rod 21 drives the film-penetrating member 22 to move to the liquid sealing film 14 and pierces the liquid sealing film 14, so that samples in the packaging tube 10 are transferred into the mixing chamber 1, the film-penetrating member 22 pierces the liquid sealing film 14, the samples flow to the stirring wheel 221 of the film-penetrating member 22, the external device drives the driving rod 21 to rotate, and accordingly the stirring wheel 221 uniformly stirs the samples and transfers the samples into the mixing chamber 1, namely the top core device 20 rotates under the action of the external device, so that the purpose of fully mixing the samples in the mixing chamber 1 is achieved.
Compared with the prior art, the core-ejecting film-piercing pipetting system provided by the utility model pierces the sealing liquid film 14 on the packaging tube 10 through the core-ejecting device 20 and uniformly stirs and transmits a sample into the mixing chamber 1. Wherein the core ejecting device 20 comprises a driving rod 21 inserted in the inserting tube 13, and a film penetrating member 22 arranged at one end of the driving rod 21. The driving rod 21 in the core jacking device 20 is inserted into the insertion tube 13 of the packaging tube 10, wherein the driving rod 21 sequentially comprises a driving section 211, a sealing section 212, a connecting section 213 and at least one sealing ring 214 sleeved on the sealing section 212. The sealing ring 214 is disposed on the sealing section 212, and the sealing section 212 is accommodated in the plug tube 13, so as to ensure tightness between the core pushing device 20 and the sealing tube 10. In addition, the length of the core pushing device 20 is larger than the sum of the heights of the packaging tube 10 and the mixing chamber 1, so that the core pushing device 20 is conveniently inserted into the mixing chamber 1, and sample transfer between the packaging tube 10 and the mixing chamber 1 is realized. When the top core film-penetrating pipetting system is in use, the driving rod 21 drives the film-penetrating member 22 to move to the liquid sealing film 14, the liquid sealing film 14 is pierced, and the external device drives the driving rod 21 to rotate, so that the sample is uniformly stirred and transferred into the mixing chamber 1. Therefore, the top core thorn film pipetting system is simple in structure and convenient to use, ensures the tightness of the sample transferring process, and improves the sample extraction effect and accuracy.
The above is only a preferred embodiment of the present utility model and is not intended to limit the scope of the present utility model, and any modifications, equivalent substitutions or improvements within the spirit of the present utility model are intended to be covered by the claims of the present utility model.
Claims (6)
1. A top-dressing pipetting system comprising a mixing chamber for receiving a sample, characterized in that: the top core thorn membrane pipetting system comprises a packaging tube arranged on the mixing chamber and a top core device inserted on the packaging tube, the packaging tube comprises a packaging tube main body, a packaging tube opening arranged at one end of the packaging tube main body, a plug tube arranged at one end of the packaging tube main body opposite to the packaging tube opening, a sealing liquid membrane arranged on the packaging tube opening, the top core device comprises a driving rod inserted in the plug tube, and a thorn membrane piece arranged at one end of the driving rod and accommodated in the packaging tube main body, the driving rod sequentially comprises a driving section, a sealing section, a connecting section and at least one sealing ring sleeved on the sealing section, the thorn membrane piece comprises a stirring wheel arranged at one end of the connecting section, and a thorn membrane piece arranged at one side of the stirring wheel opposite to the mixing chamber, and the length of the top core device is greater than the height of the packaging tube and the height of the mixing chamber so as to improve the mixing effect.
2. The top-core prick membrane pipetting system of claim 1, wherein: the sealing tube main body is close to the outer wall of one end of the opening of the sealing tube and is provided with a liquid leakage preventing device which is tightly connected with the mixing chamber, and the liquid leakage preventing device is a leakage preventing external thread.
3. The top-core prick membrane pipetting system of claim 1, wherein: the seal section comprises a seal section main body and at least one containing groove arranged on the seal section main body.
4. The top-core prick membrane pipetting system of claim 1, wherein: the core jacking device further comprises a limiting section arranged at one end of the connecting section towards the sealing section, and the diameter of the limiting section is larger than the inner diameter of the plug-in pipe.
5. The top-core prick membrane pipetting system of claim 1, wherein: the film-piercing member further comprises at least one reinforcing rib arranged between the stirring wheel and the film-piercing member.
6. The top-core prick membrane pipetting system of claim 1, wherein: the film piercing member is obliquely arranged towards one side edge of the mixing chamber.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202322808384.7U CN220999638U (en) | 2023-10-17 | 2023-10-17 | Top core thorn membrane pipetting system |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202322808384.7U CN220999638U (en) | 2023-10-17 | 2023-10-17 | Top core thorn membrane pipetting system |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN220999638U true CN220999638U (en) | 2024-05-24 |
Family
ID=91118202
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202322808384.7U Active CN220999638U (en) | 2023-10-17 | 2023-10-17 | Top core thorn membrane pipetting system |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN220999638U (en) |
-
2023
- 2023-10-17 CN CN202322808384.7U patent/CN220999638U/en active Active
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