CN220933200U - Radiation dose measuring device for simulating metabolism of radiopharmaceuticals in organs - Google Patents
Radiation dose measuring device for simulating metabolism of radiopharmaceuticals in organs Download PDFInfo
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- CN220933200U CN220933200U CN202322502455.0U CN202322502455U CN220933200U CN 220933200 U CN220933200 U CN 220933200U CN 202322502455 U CN202322502455 U CN 202322502455U CN 220933200 U CN220933200 U CN 220933200U
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- radiopharmaceutical
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- 210000000056 organ Anatomy 0.000 title claims abstract description 58
- 230000005855 radiation Effects 0.000 title claims abstract description 54
- 229940121896 radiopharmaceutical Drugs 0.000 title claims abstract description 30
- 239000012217 radiopharmaceutical Substances 0.000 title claims abstract description 30
- 230000002799 radiopharmaceutical effect Effects 0.000 title claims abstract description 30
- 230000004060 metabolic process Effects 0.000 title claims abstract description 10
- 238000000605 extraction Methods 0.000 claims abstract description 11
- 238000004088 simulation Methods 0.000 claims description 34
- 238000002347 injection Methods 0.000 claims description 22
- 239000007924 injection Substances 0.000 claims description 22
- 230000002503 metabolic effect Effects 0.000 claims description 11
- 238000004980 dosimetry Methods 0.000 claims description 9
- 230000002285 radioactive effect Effects 0.000 abstract description 18
- 239000003814 drug Substances 0.000 abstract description 13
- 229940079593 drug Drugs 0.000 abstract description 10
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract description 5
- 238000012545 processing Methods 0.000 abstract description 4
- 238000005259 measurement Methods 0.000 abstract description 3
- 230000000694 effects Effects 0.000 description 6
- 239000007788 liquid Substances 0.000 description 6
- 238000000034 method Methods 0.000 description 4
- 238000007689 inspection Methods 0.000 description 3
- 238000012546 transfer Methods 0.000 description 3
- 238000001514 detection method Methods 0.000 description 2
- 201000010099 disease Diseases 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 230000007246 mechanism Effects 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 238000005070 sampling Methods 0.000 description 2
- PNDPGZBMCMUPRI-HVTJNCQCSA-N 10043-66-0 Chemical compound [131I][131I] PNDPGZBMCMUPRI-HVTJNCQCSA-N 0.000 description 1
- 208000005189 Embolism Diseases 0.000 description 1
- 206010020850 Hyperthyroidism Diseases 0.000 description 1
- VWQVUPCCIRVNHF-OUBTZVSYSA-N Yttrium-90 Chemical compound [90Y] VWQVUPCCIRVNHF-OUBTZVSYSA-N 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 230000003213 activating effect Effects 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 201000007270 liver cancer Diseases 0.000 description 1
- 208000014018 liver neoplasm Diseases 0.000 description 1
- 230000037323 metabolic rate Effects 0.000 description 1
- 238000012544 monitoring process Methods 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 238000001959 radiotherapy Methods 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 238000001179 sorption measurement Methods 0.000 description 1
Classifications
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
- Y02E30/00—Energy generation of nuclear origin
- Y02E30/30—Nuclear fission reactors
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- Nuclear Medicine (AREA)
Abstract
The utility model relates to the technical field of radiopharmaceutical metabolism measurement and discloses a radiation dose measuring device for simulating radiopharmaceutical metabolism in an organ, which comprises a main body, wherein a turntable is rotatably connected in the main body, the lower surface of the turntable is fixedly connected with a simulated organ, the lower surface of the simulated organ is fixedly connected with a first motor, the outer wall of the first motor is fixedly connected in the main body, the top end of the simulated organ is fixedly connected with a water inlet pipe, and the outer wall of the simulated organ is fixedly connected with a plurality of uniformly symmetrical radiation detectors. According to the utility model, the plurality of radioactive detectors are arranged on the outer wall of the simulated organ, so that the position and distribution of the radioactive drug in the simulated organ can be monitored in real time, and the delivery pump is conveniently started to connect and extract the conduit with the position of the radioactive drug detected through the extraction pipe through the plurality of conduits arranged below the radioactive detectors, so that the acquisition and processing of real-time data are realized through the display screen.
Description
Technical Field
The utility model relates to the technical field of radiopharmaceutical metabolism measurement, in particular to a radiation dose measuring device for simulating the metabolism of radiopharmaceuticals in organs.
Background
Radionuclides are widely used in the treatment of various diseases, such as iodine-131 nuclide treatment of hyperthyroidism, yttrium-90 nuclide embolism treatment of liver cancer, and the like. The mechanism of the treatment is to collect nuclides in the focus area by oral administration or intravascular injection, and kill focus cells by the radiation released by the radionuclides to achieve the treatment effect. Theoretically, the dose of local radiation is directly related to the efficacy and complications. The current method for treating diseases by using the liquid nuclide cannot accurately evaluate the radiation dose around the focus, and a measuring device is needed to measure and assist the subsequent treatment.
According to the method, a device for measuring the metabolic radiation dose of the radioactive drug in a simulated organ (a main body container, a focus simulation shell is arranged in the main body container, a plurality of radiation dosimeters are distributed on the focus simulation shell, a balloon is arranged in the focus simulation shell, a dosimeter channel is arranged on the focus simulation shell, one end of the dosimeter channel extends to the central position of the focus simulation shell, the other end of the dosimeter channel extends to the outside of the main body container, a drug inlet pipe and a drug outlet pipe are communicated with the balloon, and a water inlet pipe and a water outlet pipe are arranged on the focus simulation shell) is disclosed in the bulletin No. CN 219162391U.
Disclosure of utility model
In order to overcome the defects, the utility model provides a radiation dose measuring device for simulating the metabolism of radiopharmaceuticals in an organ, and aims to solve the problems that the specific position in the simulated organ cannot be determined by medicaments, so that sampling inspection of internal liquid is inconvenient, and meanwhile, the radiation dose in the organ and tissues cannot be intuitively observed through a single radiation dosimeter.
In order to achieve the above purpose, the present utility model provides the following technical solutions:
The utility model provides a radiopharmaceuticals metabolism radiation dose measuring device in simulation organ, includes the main part, the inside rotation of main part is connected with the carousel, the inside of carousel is provided with the simulation organ, the lower fixed surface of simulation organ is connected with first motor, the outer wall fixed connection of first motor is in the inside of main part, the top fixedly connected with inlet tube of simulation organ, the outer wall fixedly connected with of simulation organ evenly symmetrical a plurality of radioactive detector, the inside fixedly connected with evenly symmetrical a plurality of pipes of outer wall of simulation organ, the inside of pipe is provided with the solenoid valve, the inner wall sliding connection of solenoid valve has the extraction tube, the one end fixedly connected with delivery pump of extraction tube, the output fixedly connected with conveyer pipe of delivery tube, the one end fixedly connected with radiation dosimeter of main part, the upper surface of main part is provided with the demonstration subassembly.
Through above-mentioned technical scheme, be provided with a plurality of radiation detector through the outer wall of simulation organ, can real-time supervision radiopharmaceutical position and distribution in the simulation organ, a plurality of pipes through the radiation detector below setting, the convenient delivery pump that starts is connected to the pipe that detects the radiopharmaceutical position through the extraction pipe, then carry out the extraction and carry the radiation doser through the conveyer pipe, realize real-time data's collection and processing through the display screen, provide instant radiation dose information, the concrete position of the unable determination simulation organ inside of most devices has been solved, so inconvenient sample inspection is carried out to inside liquid, simultaneously through the unable audio-visual problem of observing the radiation dose in organ and the tissue of single radiation doser.
Further, the display assembly comprises a support and a display screen, wherein the upper end of the support is fixedly connected to the lower surface of the display screen.
Further, the lower extreme fixed connection of support is in the upper surface of main part, display screen electric connection has the radiation dosimeter.
Through the technical scheme, the data from the radioactive detector 8 can be acquired in real time through the display screen, and the data are processed and analyzed in real time.
Further, the lower surface of the delivery pump is fixedly connected to the upper surface of the main body, and the lower surface of the radiation dosimeter is fixedly connected to the upper surface of the main body.
Through above-mentioned technical scheme, play the effect of supporting through the main part.
Further, the upper surface fixedly connected with fixed plate of main part, the inside of fixed plate is provided with electronic guide rail, electronic guide rail's outer wall sliding connection has the movable plate, the outer wall sliding connection of movable plate is in the inside of fixed plate.
Further, the inside fixedly connected with injection syringe of movable plate, the bottom middle part fixedly connected with injection head of injection syringe, the inside of injection syringe is provided with observation window, the upper surface middle part fixedly connected with air pump of movable plate, the output fixedly connected with air duct of air pump, the one end fixedly connected with of air duct is in the inside of injection syringe.
Through above-mentioned technical scheme, start electronic guide rail, drive movable plate and injection head and remove downwards, start the air pump and conveniently carry the inside of syringe with the air, extrude the radiopharmaceutical, observe the volume of injection radiopharmaceutical through the observation window.
Further, the outer wall fixedly connected with fixed block of main part, the lower surface fixedly connected with second motor of fixed block, the output fixedly connected with backup pad of second motor, the outer wall fixedly connected with arm of backup pad, the drive end fixedly connected with connecting plate of arm, the lower surface fixedly connected with of connecting plate is a plurality of vacuum chuck.
Through above-mentioned technical scheme, through starting the second motor, drive arm, connecting plate and vacuum chuck and remove, conveniently remove the simulation organ, when the inconvenient removal simulation organ of staff provides the convenience.
Further, two drawers which are vertically symmetrical are connected inside the main body in a sliding manner, and handles are fixedly connected in the middle of the outer wall of the drawer.
Through the technical scheme, the drawer is pulled by the handle, so that a plurality of medical appliances can be conveniently stored.
The utility model has the following beneficial effects:
1. According to the utility model, the outer wall of the simulated organ is provided with the plurality of radioactive detectors, so that the position and distribution of the radioactive drugs in the simulated organ can be monitored in real time, the delivery pump is conveniently started to connect the catheter with the position of the radioactive drugs detected through the extraction pipe, then the catheter is extracted and delivered to the radiation doser through the delivery pipe, the real-time data acquisition and processing are realized through the display screen, the instant radiation dose information is provided, and the problems that most devices cannot determine the specific position in the simulated organ, so that sampling inspection of internal liquid is inconvenient, and meanwhile, the observation of the radiation dose in the organ and the tissue cannot be intuitively performed through a single radiation doser are solved.
2. According to the utility model, the injection tube can be driven to move downwards by the moving plate below the electric guide rail, and the air pump is started to convey air into the injection tube through the air guide tube, so that the radioactive medicament is injected into the simulated organ, the effect of automatically injecting the radioactive medicament injection amount is achieved, and the effect of protecting staff is achieved.
Drawings
FIG. 1 is a schematic diagram of a front perspective view of a simulated intra-organ radiopharmaceutical metabolic radiation dosimetry device according to the present utility model;
FIG. 2 is a schematic representation of a simulated organ portion structure of a simulated intra-organ radiopharmaceutical metabolic radiation dosimetry device according to the present utility model;
FIG. 3 is a schematic view of the mechanism of a syringe portion of a simulated intra-organ radiopharmaceutical metabolic radiation dose measurement apparatus in accordance with the present utility model.
Legend description:
1. A main body; 2. a turntable; 3. simulating an organ; 4. a first motor; 5. a water inlet pipe; 6. a conduit; 7. an electromagnetic valve; 8. a radiation detector; 9. a transfer pump; 10. an extraction tube; 11. a delivery tube; 12. a radiation dosimeter; 13. a bracket; 14. a display screen; 15. a drawer; 16. a handle; 17. a support plate; 18. a fixed block; 19. a second motor; 20. a mechanical arm; 21. a connecting plate; 22. a vacuum chuck; 23. a fixing plate; 24. an electric guide rail; 25. a moving plate; 26. a syringe; 27. an observation window; 28. an injection head; 29. an air pump; 30. and an air duct.
Detailed Description
The following description of the embodiments of the present utility model will be made clearly and completely with reference to the accompanying drawings, in which it is apparent that the embodiments described are only some embodiments of the present utility model, but not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the utility model without making any inventive effort, are intended to be within the scope of the utility model.
Referring to fig. 1-3, one embodiment provided by the present utility model is: the utility model provides a radiopharmaceuticals metabolism radiation dose measuring device in simulation organ, including main part 1, the inside rotation of main part 1 is connected with carousel 2, the inside of carousel 2 is provided with simulation organ 3, the lower fixed surface of simulation organ 3 is connected with first motor 4, the outer wall fixed connection of first motor 4 is in the inside of main part 1, the top fixedly connected with inlet tube 5 of simulation organ 3, the outer wall fixedly connected with of simulation organ 3 evenly symmetrical a plurality of radiation detector 8, the outer wall inside fixedly connected with evenly symmetrical a plurality of pipe 6 of simulation organ 3, the inside of pipe 6 is provided with solenoid valve 7, the inner wall sliding connection of solenoid valve 7 has extraction tube 10, the one end fixedly connected with delivery pump 9 of extraction tube 10, the output fixedly connected with conveyer pipe 11 of delivery pump 9, the one end fixedly connected with radiation dosimeter 12 of conveyer pipe 11, the upper surface of main part 1 is provided with the display module.
Specifically, through the outer wall of the simulation organ 3 being provided with a plurality of radioactive detectors 8, can real-time supervision radiopharmaceutical position and distribution in the simulation organ 3, through a plurality of pipes 6 that radioactive detector 8 below set up, conveniently start delivery pump 9 and connect the pipe 6 that detects the radiopharmaceutical position through extracting tube 10, then extract, carry the radiation doser through conveyer pipe 11, realize real-time data's collection and processing through display screen 14.
Referring to fig. 2, the display assembly includes a bracket 13 and a display screen 14, and an upper end of the bracket 13 is fixedly coupled to a lower surface of the display screen 14. The lower extreme fixed connection of support 13 is in the upper surface of main part 1, and display screen 14 electrically connected with radiation dosimeter 12.
Specifically, the display assembly may be used to obtain data from the radiation detector 8 in real time and to process and analyze it in real time, such real-time monitoring and analysis functions may provide immediate radiation dose information, supporting real-time decisions made by medical researchers and clinical operators.
Referring to fig. 1, the lower surface of the transfer pump 9 is fixedly connected to the upper surface of the main body 1, and the lower surface of the radiation dosimeter 12 is fixedly connected to the upper surface of the main body 1.
Specifically, the main body 1 mainly serves to support the transfer pump 9 and the radiation dosimeter 12.
Referring to fig. 3, a fixing plate 23 is fixedly coupled to an upper surface of the main body 1, an electric guide rail 24 is provided inside the fixing plate 23, a moving plate 25 is slidably coupled to an outer wall of the electric guide rail 24, and an outer wall of the moving plate 25 is slidably coupled inside the fixing plate 23. The inside fixedly connected with syringe 26 of movable plate 25, the bottom middle part fixedly connected with syringe 28 of syringe 26, the inside of syringe 26 is provided with observation window 27, and the upper surface middle part fixedly connected with air pump 29 of movable plate 25, the output fixedly connected with air duct 30 of air pump 29, the inside at syringe 26 of one end fixedly connected with of air duct 30.
Specifically, by activating the electric guide rail 24, the moving plate 25 and the injection head 28 are driven to move downward, and the air pump 29 is activated to facilitate air delivery to the inside of the injection tube 26, to squeeze out the radiopharmaceutical, and to observe the amount of the injected radiopharmaceutical through the observation window 27.
Referring to fig. 3, the outer wall of the main body 1 is fixedly connected with a fixing block 18, the lower surface of the fixing block 18 is fixedly connected with a second motor 19, the output end of the second motor 19 is fixedly connected with a supporting plate 17, the outer wall of the supporting plate 17 is fixedly connected with a mechanical arm 20, the driving end of the mechanical arm 20 is fixedly connected with a connecting plate 21, and the lower surface of the connecting plate 21 is fixedly connected with a plurality of vacuum suction cups 22.
Specifically, the second motor 19 is started to drive the fixed block 18 and the mechanical arm 20 to rotate, the mechanical arm 20 drives the vacuum chuck 22 to move downwards, and the vacuum chuck 22 is connected with the simulated organ 3 in an adsorption manner, so that the effect of conveniently moving the simulated organ 3 is achieved, and the detection efficiency is improved.
Referring to fig. 1, two drawers 15 are slidably connected to the inside of the main body 1, and a handle 16 is fixedly connected to the middle of the outer wall of the drawer 15.
In particular, the drawer 15 is pulled by the handle 16 to facilitate storage of some medical devices.
Working principle: when the device is needed to be used, the electric slide rail is started, the movable plate 25 and the injection tube 26 are driven to move downwards under the action of the electric guide rail 24, the injection head 28 is inserted into the water inlet tube 5 of the simulated organ 3, the air pump 29 is started to convey air into the injection tube 26 through the air guide tube 30, the radioactive drug is injected into the simulated organ 3, after a period of time, the radioactive detector 8 is started, the specific position of the radioactive drug in the simulated organ 3 is detected, then a message is conveyed into the display screen 14 through the controller, the information is processed and displayed through the display screen 14, the first motor 4 is started to drive the master disc and the simulated organ 3 to rotate, the side with the radioactive drug is moved to the side of the conveying pump 9, the extracting tube 10 is connected with the guide tube 6, the electromagnetic valve 7 is opened, the liquid in the simulation organ 3 is pumped out by starting the delivery pump 9, the liquid is led into the radiation dosage machine through the delivery pipe 11, the data is finally transmitted into the display screen 14 for detection, then the data is observed and compared through the display screen 14, the biological distribution and the metabolic rate of the radiopharmaceuticals and the radiation dosages of different organs and tissues can be estimated by measuring the radiation dosimeter 12, the method has important significance for evaluating the curative effect and the safety of the radiopharmaceuticals, making a treatment plan and optimizing the radiotherapy, the second motor 19 is started to drive the fixed block 18 and the mechanical arm 20 to rotate, the mechanical arm 20 is started to drive the vacuum sucker 22 to move downwards to be connected with the simulation organ 3, the simulation organ 3 is conveniently moved, and convenience is provided when the simulation organ 3 is inconvenient to move by staff.
Finally, it should be noted that: the foregoing description is only illustrative of the preferred embodiments of the present utility model, and although the present utility model has been described in detail with reference to the foregoing embodiments, it will be apparent to those skilled in the art that modifications may be made to the embodiments described, or equivalents may be substituted for elements thereof, and any modifications, equivalents, improvements or changes may be made without departing from the spirit and principles of the present utility model.
Claims (8)
1. A radiation dose measuring device for simulating the metabolism of a radiopharmaceutical in an organ, comprising a body (1), characterized in that: the inside rotation of main part (1) is connected with carousel (2), the inside of carousel (2) is provided with simulation organ (3), the lower fixed surface of simulation organ (3) is connected with first motor (4), the outer wall fixedly connected with of first motor (4) is in the inside of main part (1), the top fixedly connected with inlet tube (5) of simulation organ (3), the outer wall fixedly connected with of simulation organ (3) evenly symmetrical a plurality of radiosondes (8), the inside fixedly connected with of outer wall of simulation organ (3) evenly symmetrical a plurality of pipe (6), the inside of pipe (6) is provided with solenoid valve (7), the inner wall sliding connection of solenoid valve (7) has extraction pipe (10), the one end fixedly connected with delivery pump (9) of extraction pipe (10), the output fixedly connected with delivery pipe (11) of delivery pipe (11), the one end fixedly connected with radiometer (12) of delivery pipe (11), the upper surface of main part (1) is provided with shows the subassembly.
2. The simulated intra-organ radiopharmaceutical metabolic radiation dosimetry device of claim 1 wherein: the display assembly comprises a support (13) and a display screen (14), wherein the upper end of the support (13) is fixedly connected to the lower surface of the display screen (14).
3. The simulated intra-organ radiopharmaceutical metabolic radiation dosimetry device of claim 2 wherein: the lower end of the bracket (13) is fixedly connected to the upper surface of the main body (1), and the display screen (14) is electrically connected with the radiation dosimeter (12).
4. The simulated intra-organ radiopharmaceutical metabolic radiation dosimetry device of claim 1 wherein: the lower surface of the delivery pump (9) is fixedly connected to the upper surface of the main body (1), and the lower surface of the radiation dosimeter (12) is fixedly connected to the upper surface of the main body (1).
5. The simulated intra-organ radiopharmaceutical metabolic radiation dosimetry device of claim 1 wherein: the upper surface fixedly connected with fixed plate (23) of main part (1), the inside of fixed plate (23) is provided with electronic guide rail (24), the outer wall sliding connection of electronic guide rail (24) has movable plate (25), the outer wall sliding connection of movable plate (25) is in the inside of fixed plate (23).
6. The simulated intra-organ radiopharmaceutical metabolic radiation dosimetry device of claim 5 wherein: the inside fixedly connected with injection syringe (26) of movable plate (25), the bottom middle part fixedly connected with injection head (28) of injection syringe (26), the inside of injection syringe (26) is provided with observation window (27), the upper surface middle part fixedly connected with air pump (29) of movable plate (25), the output fixedly connected with air duct (30) of air pump (29), the one end fixedly connected with of air duct (30) is in the inside of injection syringe (26).
7. The simulated intra-organ radiopharmaceutical metabolic radiation dosimetry device of claim 1 wherein: the outer wall fixedly connected with fixed block (18) of main part (1), the lower fixed surface of fixed block (18) is connected with second motor (19), the output fixedly connected with backup pad (17) of second motor (19), the outer wall fixedly connected with arm (20) of backup pad (17), the drive end fixedly connected with connecting plate (21) of arm (20), the lower fixed surface of connecting plate (21) is connected with a plurality of vacuum chuck (22).
8. The simulated intra-organ radiopharmaceutical metabolic radiation dosimetry device of claim 1 wherein: two drawers (15) which are vertically symmetrical are connected in the main body (1) in a sliding manner, and a handle (16) is fixedly connected in the middle of the outer wall of each drawer (15).
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CN202322502455.0U CN220933200U (en) | 2023-09-15 | 2023-09-15 | Radiation dose measuring device for simulating metabolism of radiopharmaceuticals in organs |
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CN202322502455.0U CN220933200U (en) | 2023-09-15 | 2023-09-15 | Radiation dose measuring device for simulating metabolism of radiopharmaceuticals in organs |
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