CN220919575U - Tumor molecule extraction element - Google Patents

Tumor molecule extraction element Download PDF

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Publication number
CN220919575U
CN220919575U CN202322797740.XU CN202322797740U CN220919575U CN 220919575 U CN220919575 U CN 220919575U CN 202322797740 U CN202322797740 U CN 202322797740U CN 220919575 U CN220919575 U CN 220919575U
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screw rod
mounting
base
pair
tumor
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CN202322797740.XU
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Chinese (zh)
Inventor
牟永平
王振飞
卫星
贺晓花
乔一芸
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Peking University Oncology Hospital Inner Mongolia Hospital Inner Mongolia Medical University Affiliated Oncology Hospital Inner Mongolia Autonomous Region Oncology Hospital Inner Mongolia Autonomous Region Cancer Center
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Peking University Oncology Hospital Inner Mongolia Hospital Inner Mongolia Medical University Affiliated Oncology Hospital Inner Mongolia Autonomous Region Oncology Hospital Inner Mongolia Autonomous Region Cancer Center
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Application filed by Peking University Oncology Hospital Inner Mongolia Hospital Inner Mongolia Medical University Affiliated Oncology Hospital Inner Mongolia Autonomous Region Oncology Hospital Inner Mongolia Autonomous Region Cancer Center filed Critical Peking University Oncology Hospital Inner Mongolia Hospital Inner Mongolia Medical University Affiliated Oncology Hospital Inner Mongolia Autonomous Region Oncology Hospital Inner Mongolia Autonomous Region Cancer Center
Priority to CN202322797740.XU priority Critical patent/CN220919575U/en
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Abstract

The utility model provides a tumor molecule extraction device, which relates to the technical field of molecule extraction and comprises a main body and a liquid outlet mechanism, wherein the main body comprises a base and a turntable, a mounting groove is formed in the center of the base, a pair of automatic telescopic rods are mounted at the top of the mounting groove, a mounting plate is fixedly mounted at the top of each automatic telescopic rod, the top ends of the mounting plate and the bottom ends of the turntable are connected through bearings, a placing rack is mounted at one side of the outer part of the base, a centrifugal machine is mounted at the top of the placing rack, the liquid outlet mechanism comprises a U-shaped frame, a liquid storage cylinder is inserted in the center of the top of the U-shaped frame, a vertical groove is formed in one side of the U-shaped frame, a screw rod is rotatably connected in the vertical groove, sliding rods are mounted in the vertical groove close to two sides of the screw rod, and a pair of sliding rods and the screw rod are provided with sliding plates. The utility model can effectively improve the extraction efficiency and has higher practical value.

Description

Tumor molecule extraction element
Technical Field
The utility model belongs to the technical field of molecular extraction, and particularly relates to a tumor molecular extraction device.
Background
The molecular diagnosis of tumor refers to molecular biological diagnosis technology with nucleic acid or protein as core, and is an important method for early diagnosis of tumor. The biological macromolecules related to tumor generation are detected to predict and diagnose the tumor generation, and the tumor treatment effect can be evaluated, so that references are provided for prognosis and prognosis of the tumor. Tumor markers refer to substances produced by malignant tumors or by tumor-stimulated host cells that reflect the occurrence, progression, and response to anti-tumor therapy of malignant tumors. The expression level in cells or the content change in body fluid is closely related to the occurrence, development and transformation of tumors. Tumor markers that have been found to date include embryonic proteins, glycoproteins, enzymes and isoenzymes, hormones, specific proteins, oncogene proteins, and the like.
Based on the above, the present inventors found that the following problems exist: the tumor molecules in the tumor sample need be extracted before the current tumor molecule detects, and most of the existing tumor molecule extraction is that the extractor extracts medicines such as lysate through the needle tube, holds the reagent tube with the tumor sample and injects medicines into the reagent tube, and when the medicines need to be injected into a plurality of samples, the fatigue of hands of the personnel can be caused, the extraction efficiency can be reduced, and the accuracy of the extraction effect can be influenced.
Accordingly, in view of the above, research and improvement of the existing structure and deficiency have been conducted to provide a tumor molecule extraction device for achieving the purpose of higher practical value.
Disclosure of utility model
In order to solve the technical problems, the utility model provides a tumor molecule extraction device to solve the problems in the prior art.
The purpose and the efficacy of the tumor molecule extraction device are achieved by the following specific technical means:
The utility model provides a tumor molecule extraction element, includes main part and play liquid mechanism, the main part includes base and carousel, just the mounting groove has been seted up to base center department, a pair of automatic telescopic link is installed to mounting groove top, a pair of automatic telescopic link's top fixed mounting has the mounting panel, the top of mounting panel and the bottom of carousel are passed through the bearing and are connected, the rack is installed to base outside one side, centrifuge is installed at the rack top, play liquid mechanism includes U type frame, U type frame top center department has been inserted and has been deposited a liquid section of thick bamboo, vertical groove has been seted up to U type frame one side, vertical groove inside rotates and is connected with the screw rod, just vertical groove inside is close to the screw rod both sides and all installs the slide bar, a pair of install the slide on slide bar and the screw rod.
Further, the installation piece is installed to slide one side, installation piece bottom is laminated mutually with depositing liquid section of thick bamboo top, just the piston rod is installed to installation piece bottom, the piston is installed to the piston rod bottom, the piston outside is laminated mutually with depositing liquid section of thick bamboo inner wall.
Further, a second motor is installed at the top end of one side of the U-shaped frame, and the output end of the second motor penetrates through the top end of one side of the U-shaped frame and is in transmission connection with one end of the screw rod.
Further, a transverse groove is formed in the other side of the U-shaped frame, a bidirectional screw rod is connected between the inner walls of the two sides of the transverse groove in a rotating mode, and a pair of sliding blocks are mounted on the bidirectional screw rod.
Further, a pair of clamping plates are arranged on one sides of the sliding blocks, and one end of the bidirectional screw rod penetrates through the U-shaped frame to extend to the outside and is provided with a knob.
Further, the bottom of mounting panel is installed first motor, first motor output run through the mounting panel and with carousel bottom transmission is connected, carousel top equidistance leaves and is equipped with a plurality of standing grooves.
Further, the mounting bracket is installed to base top one side, U type frame bottom and mounting bracket top fixed connection, the liquid outlet of depositing the liquid section of thick bamboo runs through the mounting bracket and extends to outside.
Further, the cabinet is placed to inside both sides of base all sliding connection, place the cabinet front and install the pull ring.
Compared with the prior art, the utility model has the following beneficial effects:
1. According to the tumor molecule extraction device, through the cooperation of the automatic telescopic rod, the mounting plate, the first motor, the rotary table, the placing groove, the mounting frame, the placing frame and the centrifugal machine, the reagent tube is inserted into the placing groove through the placing groove, and the rotary table is rotated through the first motor, so that one reagent tube on the rotary table is aligned with the liquid outlet of the liquid storage tube, the mounting plate and the rotary table can be moved upwards through the automatic telescopic rod, and the distance between the liquid outlet of the liquid storage tube and one reagent tube orifice is shortened;
2. According to the tumor molecule extraction device, through the matched use of the U-shaped frame, the second motor, the liquid storage barrel, the piston rod, the mounting block, the screw rod, the sliding plate, the bidirectional screw rod, the knob, the sliding block and the clamping plates, the bidirectional screw rod is rotated through the knob, so that the pair of sliding plates drive the pair of clamping plates to move oppositely, the liquid storage barrel is conveniently fixed, when the output end of the second motor drives the screw rod to rotate, the sliding rod and the sliding plate are in sliding connection, the sliding plate realizes linear movement under the sliding action of the screw rod and the sliding action of the sliding rod under the sliding action of the sliding rod, when the sliding plate moves upwards, the mounting block, the piston rod and the piston are driven to move upwards, the medicines such as lysate are stored in the liquid storage barrel, and when the sliding plate moves downwards, the mounting block, the piston rod and the piston rod above the sliding plate above originally are driven to move downwards, and the medicines such as lysate flow out from a liquid outlet; the utility model has the advantages of simple and reasonable structure, novel design, simple and convenient operation, effectively improved extraction efficiency and higher practical value.
Drawings
Fig. 1 is a schematic perspective view of the present utility model.
Fig. 2 is a schematic perspective view of the present utility model.
Fig. 3 is a schematic perspective view of the liquid outlet mechanism of the present utility model.
Fig. 4 is a plan view of the present utility model.
In the figure, the correspondence between the component names and the drawing numbers is:
100. A main body; 1001. a base; 1002. placing a cabinet; 1003. a pull ring; 1004. an automatic telescopic rod; 1005. a mounting plate; 1006. a first motor; 1007. a turntable; 1008. a placement groove; 1009. a mounting frame; 1010. a placing rack; 1011. a centrifuge; 200. a liquid outlet mechanism; 2001. a U-shaped frame; 2002. a second motor; 2003. a liquid storage cylinder; 2004. a piston rod; 2005. a mounting block; 2006. a screw; 2007. a slide bar; 2008. a slide plate; 2009. a two-way screw rod; 2010. a knob; 2011. a slide block; 2012. and (3) clamping plates.
Detailed Description
Embodiments of the present utility model are described in further detail below with reference to the accompanying drawings and examples. The following examples are illustrative of the utility model but are not intended to limit the scope of the utility model.
Examples
As shown in fig. 1 to 4:
the utility model provides a tumor molecule extraction device, which comprises a main body 100 and a liquid outlet mechanism 200, wherein the main body 100 comprises a base 1001 and a turntable 1007, a mounting groove is formed in the center of the base 1001, a pair of automatic telescopic rods 1004 are mounted at the top of the mounting groove, a mounting plate 1005 is fixedly mounted at the top of the automatic telescopic rods 1004, the top end of the mounting plate 1005 is connected with the bottom end of the turntable 1007 through a bearing, a placing rack 1010 is mounted at one side outside the base 1001, a centrifugal machine 1011 is mounted at the top of the placing rack 1010, the liquid outlet mechanism 200 comprises a U-shaped frame 2001, a liquid storage cylinder 2003 is inserted in the center of the top of the U-shaped frame 2001, a vertical groove is formed in one side of the U-shaped frame 2001, a screw rod is rotatably connected inside the vertical groove, sliding rods 2007 are mounted at two sides of the vertical groove, which are close to the screw rod 2006, and a sliding plate 2007 and a sliding plate 2008 are mounted on the screw rod 2006.
The mounting block 2005 is mounted on one side of the slide plate 2008, the bottom of the mounting block 2005 is attached to the top of the liquid storage cylinder, the piston rod 2004 is mounted on the bottom of the mounting block 2005, the piston is mounted at the bottom end of the piston rod 2004, the outer portion of the piston is attached to the inner wall of the liquid storage cylinder 2003, the piston rod 2004 is arranged at the bottom of the mounting block 2005, when the mounting block 2005 moves upwards under the action of the slide plate 2008, the mounting block 2005 drives the piston rod 2004 and the piston to move upwards to extract a medicament such as a lysate, and then when the mounting block 2005 moves downwards under the action of the slide plate 2008, the mounting block 2005 drives the piston rod 2004 and the piston to move downwards to discharge the medicament such as the lysate into a reagent tube for storing a tumor sample.
The output end of the second motor 2002 penetrates through the top end of one side of the U-shaped frame 2001 and is in transmission connection with one end of the screw 2006, and the screw 2006 is rotated when the second motor 2002 works by installing the second motor 2002.
The other side of the U-shaped frame 2001 is provided with a transverse groove, a bidirectional screw 2009 is rotatably connected between inner walls of two sides of the transverse groove, a pair of sliding blocks 2011 are mounted on the bidirectional screw 2009, and when the bidirectional screw 2009 rotates, the pair of sliding blocks 2011 can move oppositely through mounting the bidirectional screw 2009, so that a pair of clamping plates 2012 can be driven by a subsequent pair of sliding blocks 2011 to move oppositely, and clamping and fixing of the liquid storage cylinder 2003 can be realized.
The clamping plates 2012 are mounted on one sides of the pair of sliding blocks 2011, one end of the bidirectional screw 2009 penetrates through the U-shaped frame 2001 to extend to the outside, a knob 2010 is mounted, and the bidirectional screw 2009 serves as a power source for rotation through the mounting of the knob 2010.
Wherein, install first motor 1006 in the bottom of mounting panel 1005, first motor 1006 output run through mounting panel 1005 and with carousel 1007 bottom transmission is connected, carousel 1007 top equidistance leaves and is equipped with a plurality of standing grooves 1008, through installing first motor 1006, when its during operation, can make carousel 1007 rotate to make things convenient for reagent pipe on the carousel 1007 all can be quick draw medicines such as lysate that flow out from the liquid outlet, through seting up standing groove 1008, conveniently insert the reagent pipe in standing groove 1008.
Wherein, the mounting bracket 1009 is installed to base 1001 top one side, U type frame 2001 bottom and mounting bracket 1009 top fixed connection, the liquid outlet of a liquid storage section of thick bamboo 2003 runs through mounting bracket 1009 and extends to the outside.
Wherein, the inside both sides of base 1001 all sliding connection has places cabinet 1002, place cabinet 1002 openly and install the pull ring 1003, place cabinet 1002 through the installation, conveniently place some instruments that need used in the extraction process, through installing pull ring 1003, conveniently pull ring 1003 through dragging, will place cabinet 1002 and take out.
Specific use and action of the embodiment:
When the product is used, whether each mechanism in the tumor molecule extraction device is complete is checked, after the completion is ensured, a knob 2010 is rotated, a bidirectional screw rod 2009 is rotated to drive a pair of sliding blocks 2011 and a pair of clamping plates 2012 to move oppositely, a liquid storage tube 2003 is fixed, a second motor 2002 is started, when the output end of the second motor 2002 drives a screw rod 2006 to rotate, the sliding plate 2008 moves under the rotation action of the screw rod 2006 and the sliding action of a sliding rod 2007, when medicines such as lysate and the like are required to be stored in the liquid storage tube 2003, a small part of the lysate is placed in the measuring tube, then the measuring tube is attached to a liquid outlet, when the sliding plate 2008 moves upwards, a mounting block 2005, a piston rod 2004 and a piston are driven to move upwards, the lysate in the measuring tube is extracted into the liquid storage tube 2003, then a reagent tube with the crushed tumor sample in the inside is inserted into a placing groove 1008, the first motor 1006 is started to rotate the turntable 1007 to align one of the reagent tubes with the liquid outlet of the liquid storage cylinder 2003, then the automatic telescopic rod 1004 is started to move the mounting plate 1005 and the turntable 1007 upwards to draw the distance between the liquid outlet of the liquid storage cylinder 2003 and one of the reagent tube openings, so as to reduce the possibility of splashing of reagents such as pyrolysis liquid and the like due to too far away from the reagent tube openings, then the second motor 2002 is used to rotate the screw 2006 to move the sliding plate 2008 downwards to drive the mounting block 2005 and the piston rod 2004 and the piston which are originally above to move downwards, the reagents such as pyrolysis liquid and the like flow out from the liquid outlet and flow into the reagent tube, then the mounting plate 1005 is moved downwards through the pair of automatic telescopic rods 1004 and the first motor 1006 to align the next reagent tube opening with the liquid outlet, the steps are repeated, after the pyrolysis liquid is injected into the reagent tube is placed inside the centrifuge 1011 on one side of the base 1001, after filling the placement hole inside the centrifuge 1011, the centrifuge 1011 is started to centrifuge.
The embodiments of the utility model have been presented for purposes of illustration and description, and are not intended to be exhaustive or limited to the utility model in the form disclosed. Many modifications and variations will be apparent to those of ordinary skill in the art. The embodiments were chosen and described in order to best explain the principles of the utility model and the practical application, and to enable others of ordinary skill in the art to understand the utility model for various embodiments with various modifications as are suited to the particular use contemplated.

Claims (8)

1. A tumor molecule extraction device, characterized in that: including main part (100) and play liquid mechanism (200), main part (100) include base (1001) and carousel (1007), just mounting groove has been seted up in base (1001) center department, a pair of automatic telescopic link (1004) are installed at mounting groove top, a pair of top fixed mounting of automatic telescopic link (1004) has mounting panel (1005), the top of mounting panel (1005) and the bottom of carousel (1007) are passed through the bearing and are connected, rack (1010) are installed to base (1001) outside one side, centrifuge (1011) are installed at rack (1010) top, play liquid mechanism (200) include U type frame (2001), U type frame (2001) top center department is inserted and is equipped with a liquid storage section of thick bamboo (2003), vertical groove has been seted up to U type frame (2001) one side, vertical groove inside rotation is connected with screw rod (2006), just vertical groove inside is close to screw rod (2007) both sides, a pair of slide rod (2007) and screw rod (2006) are installed slide (2008) on 2006).
2. The tumor molecule extraction apparatus of claim 1, wherein: the device is characterized in that a mounting block (2005) is mounted on one side of the sliding plate (2008), the bottom of the mounting block (2005) is attached to the top of the liquid storage cylinder (2003), a piston rod (2004) is mounted at the bottom of the mounting block (2005), a piston is mounted at the bottom end of the piston rod (2004), and the outer portion of the piston is attached to the inner wall of the liquid storage cylinder (2003).
3. The tumor molecule extraction apparatus of claim 1, wherein: the top end of one side of the U-shaped frame (2001) is provided with a second motor (2002), and the output end of the second motor (2002) penetrates through the top end of one side of the U-shaped frame (2001) and is in transmission connection with one end of a screw rod (2006).
4. A tumor molecule extraction device according to claim 3, wherein: a transverse groove is formed in the other side of the U-shaped frame (2001), a bidirectional screw rod (2009) is rotatably connected between inner walls of two sides of the transverse groove, and a pair of sliding blocks (2011) are mounted on the bidirectional screw rod (2009).
5. The tumor molecule extraction apparatus of claim 4, wherein: clamping plates (2012) are arranged on one sides of the pair of sliding blocks (2011), and one end of the bidirectional screw rod (2009) penetrates through the U-shaped frame (2001) to extend to the outside and is provided with a knob (2010).
6. The tumor molecule extraction apparatus of claim 1, wherein: the bottom of mounting panel (1005) is installed first motor (1006), first motor (1006) output run through mounting panel (1005) and with carousel (1007) bottom transmission is connected, a plurality of standing grooves (1008) are left in carousel (1007) top equidistance.
7. The tumor molecule extraction apparatus of claim 1, wherein: install mounting bracket (1009) in base (1001) top one side, U type frame (2001) bottom and mounting bracket (1009) top fixed connection, the liquid outlet of a liquid storage section of thick bamboo (2003) runs through mounting bracket (1009) and extends to the outside.
8. The tumor molecule extraction apparatus of claim 7, wherein: the base (1001) is characterized in that two sides of the inside of the base are both connected with a placing cabinet (1002) in a sliding mode, and pull rings (1003) are arranged on the front face of the placing cabinet (1002).
CN202322797740.XU 2023-10-18 2023-10-18 Tumor molecule extraction element Active CN220919575U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202322797740.XU CN220919575U (en) 2023-10-18 2023-10-18 Tumor molecule extraction element

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202322797740.XU CN220919575U (en) 2023-10-18 2023-10-18 Tumor molecule extraction element

Publications (1)

Publication Number Publication Date
CN220919575U true CN220919575U (en) 2024-05-10

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ID=90937298

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202322797740.XU Active CN220919575U (en) 2023-10-18 2023-10-18 Tumor molecule extraction element

Country Status (1)

Country Link
CN (1) CN220919575U (en)

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