CN220907477U - Heating device for reaction plate - Google Patents
Heating device for reaction plate Download PDFInfo
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- CN220907477U CN220907477U CN202322578971.1U CN202322578971U CN220907477U CN 220907477 U CN220907477 U CN 220907477U CN 202322578971 U CN202322578971 U CN 202322578971U CN 220907477 U CN220907477 U CN 220907477U
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- heating
- reaction plate
- reaction
- groove
- main body
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- 238000010438 heat treatment Methods 0.000 title claims abstract description 109
- 238000006243 chemical reaction Methods 0.000 title claims abstract description 101
- 238000004026 adhesive bonding Methods 0.000 abstract description 2
- 238000005192 partition Methods 0.000 abstract description 2
- 238000003752 polymerase chain reaction Methods 0.000 description 9
- 238000000034 method Methods 0.000 description 8
- 239000004642 Polyimide Substances 0.000 description 4
- 239000011810 insulating material Substances 0.000 description 4
- 229920001721 polyimide Polymers 0.000 description 4
- 239000000919 ceramic Substances 0.000 description 3
- 239000012634 fragment Substances 0.000 description 3
- 238000000638 solvent extraction Methods 0.000 description 3
- 239000004964 aerogel Substances 0.000 description 2
- 238000000137 annealing Methods 0.000 description 2
- 238000004925 denaturation Methods 0.000 description 2
- 230000036425 denaturation Effects 0.000 description 2
- 238000010586 diagram Methods 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 239000000835 fiber Substances 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 1
- 238000005485 electric heating Methods 0.000 description 1
- 230000007613 environmental effect Effects 0.000 description 1
- 238000009413 insulation Methods 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000000465 moulding Methods 0.000 description 1
- 238000006116 polymerization reaction Methods 0.000 description 1
- 238000004321 preservation Methods 0.000 description 1
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- Devices For Use In Laboratory Experiments (AREA)
Abstract
The utility model provides a heating device for a reaction plate, which relates to the technical field of heating equipment and adopts the main technical scheme that: comprising a main body and a heating block. The upper plate surface of the main body is provided with a placing groove, the number of the heating blocks is a plurality of, and the plurality of heating blocks are all arranged on the bottom of the placing groove in a gluing mode, a pasting mode and the like. The upper surfaces of the heating blocks jointly form a heating zone, and the heating zone corresponds to the bottoms of the reaction holes on the reaction plate. Through the heating blocks, the aim of carrying out partition heating on the reaction plate placed in the placing groove is fulfilled. Simultaneously, reach and utilize the standing groove to carry out spacingly to the reaction plate to reduce the purpose of reaction plate slip risk.
Description
Technical Field
The utility model relates to the technical field of heating equipment, in particular to a heating device for a reaction plate.
Background
Polymerase Chain Reaction (PCR) is a molecular biological technique used to amplify specific DNA fragments. The PCR consists of three basic reaction steps of denaturation, annealing and extension, and the PCR instrument carries out denaturation, annealing and polymerization treatment on amplified DNA fragments by controlling the sample to reach different temperatures so as to achieve the aim of amplifying the quantity of the DNA fragments by times.
In the course of PCR, the means for placing the sample is called a reaction plate and is usually composed of a plurality of wells, for example, 8-well, 12-well, 96-well, etc. The reaction plate itself cannot heat the sample, and a heating device is required to heat the reaction plate.
Most of the existing heating devices are used for integrally heating the whole reaction plate, and the problem that the reaction plate with a small number of placed samples or multiple samples cannot be heated in a partitioning manner exists.
Disclosure of utility model
The utility model aims to provide a heating device for a reaction plate, which achieves the aim of heating the reaction plate in a partitioning way.
The utility model is realized by the following technical scheme:
A heating device for a reaction plate, comprising: the heating device comprises a main body and a heating block, wherein a placing groove is formed in the upper plate surface of the main body; the placing groove is used for placing the reaction plate; the heating blocks are distributed on the bottom of the placing groove, so that the upper surfaces of the heating blocks form a heating zone together; the heating area is used for corresponding to the bottom of the reaction hole on the reaction plate.
Optionally, the heating device for the reaction plate further comprises a heat conducting block; the heat conducting block is arranged on the heating block; the upper plate surface of the heat conducting block is provided with a groove; the groove is used for being attached to the bottom of the reaction hole on the reaction plate.
Optionally, the plurality of heating blocks are uniformly arranged along the length direction of the main body.
Optionally, a gap is provided between two adjacent heating blocks.
Optionally, the groove wall of the placing groove comprises an inclined section and a vertical section; the inclined section gradually inclines to the inner side of the placing groove along the direction from top to bottom; the vertical section is connected to the lower end of the inclined section.
Optionally, a connecting part is arranged between two adjacent groove walls of the placing groove; the inner wall of the connecting part is of an arc-shaped structure which is bent towards the direction far away from the placing groove.
Optionally, a controller is arranged inside the main body; the output end of the controller is used for being connected with the heating block.
Optionally, a touch screen is embedded on the side wall of the main body; the output end of the touch screen is used for being connected with the controller.
Compared with the prior art, the utility model has the following advantages and beneficial effects:
① The upper plate surface of the main body is provided with a placing groove. The purpose of limiting the reaction plate by using the placing groove so as to reduce the sliding risk of the reaction plate is achieved.
② A plurality of heating blocks are distributed on the bottom of the placing groove. Through the heating blocks, the aim of carrying out partition heating on the reaction plate placed in the placing groove is fulfilled.
Drawings
In order to more clearly illustrate the technical solutions of the exemplary embodiments of the present utility model, the drawings that are needed in the examples will be briefly described below, it being understood that the following drawings only illustrate some examples of the present utility model and therefore should not be considered as limiting the scope, and that other related drawings may be obtained from these drawings without inventive effort for a person skilled in the art. In the drawings:
FIG. 1 is a schematic diagram showing a front view of a heating apparatus for a reaction plate according to an embodiment;
FIG. 2 is a schematic top view of a heating device for a reaction plate according to an embodiment;
FIG. 3 is a schematic view of the structure of FIG. 2 taken along line A-A;
FIG. 4 is a schematic electrical structure of a heating device for a reaction plate according to an embodiment.
In the drawings, the reference numerals and corresponding part names:
1-a main body; 2-a placing groove; 3-heating blocks; 4-a heat conducting block; 5-grooves; 6-gap;
7-groove walls; 71-inclined section; 72-vertical section;
8-connecting part; 9-a controller; 10-touch screen.
Detailed Description
For the purpose of making apparent the objects, technical solutions and advantages of the present utility model, the present utility model will be further described in detail with reference to the following examples and the accompanying drawings, wherein the exemplary embodiments of the present utility model and the descriptions thereof are for illustrating the present utility model only and are not to be construed as limiting the present utility model.
In the process of performing PCR, on the one hand, the condition that the number of samples is insufficient and only part of the reaction wells on the reaction plate can be filled is frequently encountered. On the other hand, it is often the case that PCR is performed simultaneously on a plurality of types of samples, and the temperature at which the different types of samples need to be heated is also different. However, most of the existing heating devices for PCR heat the entire reaction plate, and the purpose of heating the reaction holes on the reaction plate in a partitioned manner cannot be achieved.
Accordingly, the present embodiment provides a heating device for a reaction plate, which includes a main body 1 and a heating block 3, as shown in fig. 1 to 3.
A placement groove 2 is provided on the upper plate surface of the main body 1. Specifically, the placement groove 2 may be formed on the main body 1 by an integral molding. The boss of the annular structure can be fixed on the upper plate surface of the main body 1 in a screwed manner, so that the placing groove 2 is formed between the inner wall of the boss and the upper plate surface of the main body 1.
The placement groove 2 is used for placing a reaction plate, and the placement groove 2 is matched with the reaction plate. That is, after the reaction plate is placed in the placement groove 2, the outer side of the side wall of the reaction plate is bonded to the inner side of the groove wall 7 of the placement groove 2. The purpose of limiting the reaction plate so as to reduce the sliding risk of the reaction plate is achieved.
The heating block 3 may adopt a PI heating tape, which is an electric heating sheet made of Polyimide (PI) as a main material, and may be used for heating and heat preservation. The PI heating belt has the advantages of high efficiency, energy saving, environmental protection, safety, accurate control, long service life and the like. And the heating block 3 has the advantages of quick heat transfer up and down and good heat insulation effect of two side surfaces.
The number of the heating blocks 3 is provided with a plurality of heating blocks 3 which are all arranged on the bottom of the placing groove 2 in a gluing, sticking and other modes. The upper surfaces of the plurality of heating blocks 3 jointly form a heating zone, and the heating zone corresponds to the bottoms of the reaction holes on the reaction plate. By this structure, the reaction plate in the placement tank 2 is heated in a partitioned manner.
In the implementation process, when the number of the samples is insufficient and only part of the reaction holes on the reaction plate can be filled. After the reaction plate is placed in the placing groove 2, the purposes of carrying out zone heating on the reaction plate and reducing heat loss can be achieved only by controlling the operation of the heating blocks 3 corresponding to the reaction holes containing the samples on the reaction plate.
When the PCR needs to be carried out on multiple types of samples on the reaction plate at the same time, the purpose of heating the reaction plate in a partitioning way and heating each sample to the required temperature can be achieved by controlling each heating block 3 to heat each type of sample.
In order to improve the uniformity of heating the reaction holes on the reaction plate by the heating block 3 during the heating process. In this embodiment, as shown in fig. 1, the heating device for a reaction plate further includes a heat conduction block 4. The heat conducting block 4 can be made of ceramics, metal and other materials. The heat conducting block 4 is arranged on the heating block 3. Specifically, the heat conducting block 4 is disposed in the placement groove 2 of the main body 1 by screwing, fixing, etc., and is attached above the heating block 3. A groove 5 is arranged on the upper plate surface of the heat conduction block 4, and the groove 5 is used for being attached to the bottom of the reaction hole on the reaction plate.
To further reduce the extent to which the heating temperatures interact between adjacent heat conducting blocks 4. An aerogel, ceramic fiber, or other insulating material may be filled between adjacent heat conducting blocks 4. The heat-insulating material can be coated or the heat-insulating film can be stuck on the two sides of the heat-conducting block 4.
In the implementation process, the bottoms of the reaction holes on most reaction plates are of conical structures with gradually reduced cross sectional areas from top to bottom, and the outer walls of the bottoms of the reaction holes are of smooth arc structures. Therefore, the heat conducting block 4 is provided with the groove 5 which is matched with the bottom of the reaction hole on the reaction plate, so that the bottom of the reaction hole is attached in the groove 5 when the reaction plate is heated, and the purpose of improving the heating uniformity is achieved.
In this embodiment, as shown in fig. 1, the plurality of heating blocks 3 are uniformly arranged along the length direction of the main body 1. Through the structure, the aim of single-row temperature control of the reaction holes on the reaction plate is fulfilled.
In the specific implementation process, the heating blocks 3 can be uniformly arranged on the bottom of the placement groove 2 along the longitudinal and transverse directions, so that the heating blocks 3 are in one-to-one correspondence with the reaction holes on the reaction plate. So as to achieve the purpose of respectively controlling the temperature of each reaction hole on the reaction plate and improving the heating precision of each reaction hole.
In order to reduce the extent to which the heating temperatures interact between adjacent heating blocks 3. In this embodiment, as shown in fig. 2, a gap 6 is provided between two adjacent heating blocks 3, and the gap 6 corresponds to the interval between the reaction holes on the reaction plate. Through this structure, when adjacent heating blocks 3 simultaneously work, through the clearance 6 between adjacent heating blocks 3, can effectively reduce the effect of heat transfer between two adjacent heating blocks 3 to reach the purpose that reduces between the adjacent heating blocks 3, the degree of heating temperature influence each other.
Meanwhile, in order to further reduce the degree to which the heating temperatures are affected each other between the adjacent heating blocks 3, an insulating material such as aerogel or ceramic fiber may be filled between the adjacent heating blocks 3. The heat insulating material can be coated or the heat insulating film can be stuck on the two sides of the heating block 3.
To facilitate the placement of the reaction plate into the placement groove 2 on the body 1. In the present embodiment, as shown in fig. 3, the groove wall 7 of the above-described placement groove 2 includes an inclined section 71 and a vertical section 72. Wherein the inclined section 71 is gradually inclined toward the inside of the placement groove 2 in a top-down direction. A vertical section 72 is connected to the lower end of the inclined section 71. By this structure, in the process of putting the reaction plate into the placement tank 2, the reaction plate is guided by the inclined section 71, so that the purpose of putting the reaction plate into the lower end of the inclined section 71 is achieved. Meanwhile, after the reaction plate is drawn into the lower end of the inclined section 71, the vertical section 72 at the lower end of the inclined section 71 can limit the lower end of the side wall of the reaction plate, so that the purposes of reducing the inclination and sliding risks of the reaction plate are achieved.
Most of the existing reaction plates are of cuboid structures, so that risks of placing the reaction plates in the placing grooves 2 are difficult to achieve due to the fact that the reaction plates are inclined in the process of placing the reaction plates in the placing grooves 2, the corners of the reaction plates are abutted to the corners of the placing grooves 2. In this embodiment, as shown in fig. 1, the above-mentioned placement groove 2 has a rectangular structure as a whole, and a connecting portion 8 is disposed between two adjacent groove walls 7, and the inner wall of the connecting portion 8 has an arc-shaped structure that is curved in a direction away from the placement groove 2. Through this structure, in the process of putting the reaction plate into the placing groove 2, the angle of the reaction plate can fall in the arc-shaped connecting part 8, so as to achieve the purpose of being convenient for putting the reaction plate into the placing groove 2.
For the purpose of facilitating control of the heating temperature of each heating block 3. In this embodiment, as shown in fig. 3, a controller 9 is provided inside the main body 1. The controller 9 may be a MCU of the prior art, and its working principle is shown in fig. 4. The number of controllers 9 may be one, and the output end of one controller 9 is connected to the input end of each heating block 3. The purpose of controlling the heating temperature of each heating block 3 by the controller 9 is achieved. The number of the controllers 9 may also correspond to the number of the heating blocks 3, and each control is connected to each heating block 3 in a one-to-one correspondence. The purpose of controlling each heating block 3 by a plurality of controllers 9 is achieved.
In order to achieve the aim of being convenient for the staff to adjust the heating temperature of each heating block 3. In this embodiment, as shown in fig. 1, a touch screen 10 is embedded in a side wall of the main body 1. The touch screen 10 may be a schrader touch screen of the prior art, and its working principle diagram may be seen in fig. 4. Specifically, a mounting hole is formed in a side wall of the main body 1, and the touch screen 10 is fixed in the mounting hole by screwing, clamping or the like. The output of the touch screen 10 is electrically connected to the input of the controller 9. By this structure, the purpose of facilitating the operator to select the heating block 3 to be operated and to adjust the heating temperature of the heating block 3 through the touch screen 10 is achieved.
The foregoing description of the embodiments has been provided for the purpose of illustrating the general principles of the utility model, and is not meant to limit the scope of the utility model, but to limit the utility model to the particular embodiments, and any modifications, equivalents, improvements, etc. that fall within the spirit and principles of the utility model are intended to be included within the scope of the utility model.
Claims (7)
1. A heating device for a reaction plate, comprising:
A main body (1), wherein a placement groove (2) is arranged on the upper plate surface of the main body (1); the placing groove (2) is used for placing a reaction plate;
The heating blocks (3) are arranged on the bottom of the placing groove (2) so that the upper surfaces of the heating blocks (3) form a heating zone together; the heating area is used for corresponding to the bottom of the reaction hole on the reaction plate;
Also comprises a heat conducting block (4);
the heat conducting block (4) is arranged on the heating block (3);
the upper plate surface of the heat conduction block (4) is provided with a groove (5);
The groove (5) is used for being attached to the bottom of the reaction hole on the reaction plate.
2. A heating apparatus for a reaction plate according to claim 1, wherein:
the heating blocks (3) are uniformly arranged along the length direction of the main body (1).
3. A heating apparatus for a reaction plate according to claim 2, wherein:
a gap (6) is arranged between two adjacent heating blocks (3).
4. A heating apparatus for a reaction plate according to claim 1, wherein:
The groove wall (7) of the placing groove (2) comprises an inclined section (71) and a vertical section (72);
The inclined section (71) gradually inclines to the inner side of the placing groove (2) along the direction from top to bottom;
the vertical section (72) is connected to the lower end of the inclined section (71).
5. A heating apparatus for a reaction plate according to claim 1, wherein:
a connecting part (8) is arranged between two adjacent groove walls (7) of the placing groove (2);
The inner wall of the connecting part (8) is of an arc-shaped structure which is bent towards the direction far away from the placing groove (2).
6. A heating apparatus for a reaction plate according to claim 1, wherein: a controller (9) is arranged inside the main body (1);
the output end of the controller (9) is used for being connected with the heating block (3).
7. The heating apparatus for a reaction plate according to claim 6, wherein:
A touch screen (10) is embedded on the side wall of the main body (1);
the output end of the touch screen (10) is used for being connected with the controller (9).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202322578971.1U CN220907477U (en) | 2023-09-21 | 2023-09-21 | Heating device for reaction plate |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202322578971.1U CN220907477U (en) | 2023-09-21 | 2023-09-21 | Heating device for reaction plate |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN220907477U true CN220907477U (en) | 2024-05-07 |
Family
ID=90913458
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202322578971.1U Active CN220907477U (en) | 2023-09-21 | 2023-09-21 | Heating device for reaction plate |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN220907477U (en) |
-
2023
- 2023-09-21 CN CN202322578971.1U patent/CN220907477U/en active Active
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