CN220802326U - Separation and purification filter device for biopharmaceuticals - Google Patents
Separation and purification filter device for biopharmaceuticals Download PDFInfo
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- CN220802326U CN220802326U CN202322251834.7U CN202322251834U CN220802326U CN 220802326 U CN220802326 U CN 220802326U CN 202322251834 U CN202322251834 U CN 202322251834U CN 220802326 U CN220802326 U CN 220802326U
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- fixed block
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- 238000000926 separation method Methods 0.000 title claims abstract description 22
- 238000000746 purification Methods 0.000 title claims abstract description 20
- 229960000074 biopharmaceutical Drugs 0.000 title claims description 15
- 238000001914 filtration Methods 0.000 claims abstract description 28
- 238000003756 stirring Methods 0.000 claims description 17
- 238000007789 sealing Methods 0.000 claims description 13
- 238000010030 laminating Methods 0.000 claims description 10
- 238000012856 packing Methods 0.000 claims description 7
- 239000007787 solid Substances 0.000 claims description 4
- 239000003814 drug Substances 0.000 abstract description 38
- 239000007788 liquid Substances 0.000 abstract description 23
- 239000002245 particle Substances 0.000 abstract description 11
- 230000000694 effects Effects 0.000 description 14
- 238000000034 method Methods 0.000 description 9
- 239000008187 granular material Substances 0.000 description 7
- 239000000706 filtrate Substances 0.000 description 3
- 238000012423 maintenance Methods 0.000 description 3
- 239000000843 powder Substances 0.000 description 3
- 239000002994 raw material Substances 0.000 description 3
- 241001465754 Metazoa Species 0.000 description 2
- 230000000903 blocking effect Effects 0.000 description 2
- 229940079593 drug Drugs 0.000 description 2
- 230000009977 dual effect Effects 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 244000005700 microbiome Species 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 1
- 239000012620 biological material Substances 0.000 description 1
- 150000001720 carbohydrates Chemical class 0.000 description 1
- 230000001413 cellular effect Effects 0.000 description 1
- 238000004891 communication Methods 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 238000004821 distillation Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 230000002068 genetic effect Effects 0.000 description 1
- 238000002649 immunization Methods 0.000 description 1
- 230000003053 immunization Effects 0.000 description 1
- 239000012535 impurity Substances 0.000 description 1
- 238000009434 installation Methods 0.000 description 1
- 150000002632 lipids Chemical class 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 102000039446 nucleic acids Human genes 0.000 description 1
- 108020004707 nucleic acids Proteins 0.000 description 1
- 150000007523 nucleic acids Chemical class 0.000 description 1
- 230000000050 nutritive effect Effects 0.000 description 1
- 230000000144 pharmacologic effect Effects 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
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- Centrifugal Separators (AREA)
Abstract
The utility model relates to the technical field of biological pharmacy, in particular to a biological pharmacy separation and purification filtering device which comprises a fitting piece, a filtering mechanism, a clamping piece and a top cover, wherein the filtering mechanism is arranged at the middle end of the inside of the fitting piece, the clamping piece is arranged at the bottom of the filtering mechanism, the top cover is arranged at the top end of the fitting piece, and the filtering mechanism comprises a fixing ring, a ring groove, a first filter screen, a fixing block and an elastic piece. According to the utility model, the elastic piece is connected to the bottom of the fixed block, the first filter screen is embedded in the annular groove through the fixed block, the elastic piece is abutted and installed, the liquid medicine is put into the tank body through the feed inlet, the liquid medicine on the first filter screen is stirred through connection with the motor, and the inside of the tank body is provided with a double-filtering structure, so that large particles can be effectively removed from the liquid medicine in a separation engineering, and the problem that the medicine in the first filter screen cannot be filtered well and is blocked due to excessive particles on the filter screen is solved.
Description
Technical Field
The utility model relates to the technical field of biological pharmacy, in particular to a separation, purification and filtration device for biological pharmacy.
Background
The biological pharmaceutical raw materials mainly comprise natural biological materials including microorganisms, human bodies, animals, plants, marine organisms and the like. With the development of biotechnology, purposefully artificially produced biological raw materials are the main source of current biopharmaceutical raw materials. Such as animal materials prepared by immunization, microorganisms or other cellular materials prepared by modification of genetic constructs, and the like. The biological medicine has the characteristics of high pharmacological activity, small toxic and side effects and high nutritive value. The biological medicine mainly comprises proteins, nucleic acids, saccharides, lipids and the like.
The separation and purification filter equipment is needed to be used in the biopharmaceutical process, chinese patent discloses a biopharmaceutical separation and purification filter equipment (grant bulletin number CN 202123059227.8), this patent technology can be reached through not only can mix the stirring to inside liquid medicine, can guarantee the homogeneity that is heated when distilling, guarantee the effect of distillation, can also scrape the equipment inner wall, can avoid the impurity adhesion that separates out at the inner wall, be convenient for clear up it, but in the practical process, can not be fine filter its inside granule medicine, can often block up because of the granule on the filter screen is too much, make filtration efficiency reduce, and then make purification effect general problem appear.
Accordingly, a person skilled in the art provides a biopharmaceutical separation and purification filtering device to solve the above-mentioned problems in the background art.
Disclosure of utility model
The utility model aims to solve the defects that in the prior art, the filtering efficiency is reduced and the purification effect is general because the filtering of the internal granular medicine is not very good and the filter screen is often blocked due to excessive granules on the filter screen.
In order to achieve the above purpose, the present utility model adopts the following technical scheme: the utility model provides a bio-pharmaceuticals separation purification filter equipment, includes laminating piece, filter mechanism, block piece and top cap, the inside middle-end of laminating piece is provided with filter mechanism, and filter mechanism's bottom is provided with the block piece, laminating piece's top is provided with the top cap, filter mechanism includes solid fixed ring, annular, first filter screen, fixed block and elastic component, and gu the inside of solid fixed ring is provided with the annular, gu the top of solid fixed ring is provided with first filter screen, and the both sides of first filter screen are provided with the fixed block, the bottom of fixed block is provided with the elastic component.
The effects achieved by the components are as follows: the setting through the fixed block is used for cooperating with the annular to place stable to first filter screen, accomplish spacing process towards inside rotation afterwards, avoid first filter screen to appear droing at vibration filtration's in-process.
Preferably, the first filter screen forms a clamping structure with the fixing ring through the fixing block, and the fixing block forms an elastic structure with the annular groove through the elastic piece.
The effects achieved by the components are as follows: the bottom through the fixed block is connected with the elastic component, passes through the fixed block embedding in the annular at first filter screen, rotates inwards afterwards and removes, supports tightly by the elastic component, and the outside miniature bobbing machine of cooperation makes it handle through the mode of oscillating from top to bottom, avoids the medicine granule to cause the jam to the filter screen, improves the filtration rate and the quality of filtrate of medicament.
Preferably, the clamping piece comprises a fixing rod, a clamping groove and a second filter screen, the clamping groove is formed in the bottom end of the fixing rod, and the second filter screen is arranged at the top end of the clamping groove.
The effects achieved by the components are as follows: the size through the second filter screen is the same with the size of draw-in groove for the second filter screen embedding is in the draw-in groove, also is convenient for follow-up dismantles simultaneously and changes, and separation purification filter equipment inside sets up to dual filtration, makes the liquid medicine can effectually reject big granule in the separation engineering.
Preferably, the top cap includes cover, pan feeding mouth, motor, puddler and fork type sword, and top one side of cover is provided with the pan feeding mouth, the top middle part of cover is provided with the motor, and the bottom of motor is provided with the puddler, the avris of puddler is provided with fork type sword.
The effects achieved by the components are as follows: the liquid medicine is put into the tank body through the feed inlet, the stirring rod is driven to rotate through the motor, then the liquid medicine on the first filter screen is stirred, the fluidity of the liquid medicine is effectively increased, and efficient liquid drainage is facilitated.
Preferably, the stirring rod is connected with the fork-shaped knife, and the motor is rotationally connected with the stirring rod.
The effects achieved by the components are as follows: the surface through the puddler has the screw thread cutter, has detachable fork type sword at the outside surface mounting of its puddler simultaneously, through being connected with the motor to stir inside, fork type sword can be along the puddler for the screw thread concatenation, the dismouting maintenance of later stage to fork type sword of being convenient for.
Preferably, the laminating piece includes a jar body, rand, packing ring, sealing washer and miniature bobbing machine, and the middle part of jar body is provided with the rand, the inside of rand is provided with the packing ring, and the avris of packing ring is provided with the sealing washer, the outside bottom of rand is provided with miniature bobbing machine.
The effects achieved by the components are as follows: the first filter screen is clamped inside the clamping ring and matched with the vibration of the external micro vibrator, so that the first filter screen and the elastic piece in the interior are repeatedly elastic, the filter screen is repeatedly moved up and down, and accordingly large-particle medicine powder on the filter screen is vibrated, and the phenomenon that the filter screen is blocked by medicine particles is avoided.
Preferably, the top cover and the tank body form a clamping structure through the clamping ring, and the top cover is tightly attached to the gasket.
The effects achieved by the components are as follows: be provided with through jar body top with jar lid bottom assorted rand to the block of lid on jar body top of being convenient for all is provided with packing ring and sealing washer owing to the inside of rand, thereby double seal handles and avoids influencing the reaction effect, improves the leakproofness, thereby increases the stability when the lid is placed through outer end bolt simultaneously.
In summary, the beneficial effects of the utility model are as follows: the bottom of fixed block is connected with the elastic component, passes through the fixed block embedding in the annular at first filter screen, supports tightly the installation by the elastic component, and its pan feeding mouth is put into the jar internal with the liquid medicine, stirs the liquid medicine on the first filter screen through being connected with the motor, and its inside sets up to dual filtration for the liquid medicine can effectually reject big granule in the separation engineering.
According to the utility model, the liquid medicine is put into the tank body through the feeding hole, the surface of the stirring rod is provided with the threaded cutter, and meanwhile, the detachable fork-shaped cutter is arranged on the outer surface of the stirring rod, and is connected with the motor, so that the liquid medicine on the first filter screen is stirred, the fluidity of the liquid medicine is effectively increased, the efficient liquid discharge is facilitated, the fork-shaped cutter can be spliced along the stirring rod in a threaded manner, and the later disassembly, assembly and maintenance of the fork-shaped cutter are facilitated.
According to the utility model, the clamping ring matched with the bottom end of the tank cover is arranged at the top end of the tank body, so that the tank cover is conveniently clamped at the top end of the tank body, the gasket and the sealing ring are arranged in the clamping ring, the double sealing treatment is performed, so that the influence on the reaction effect is avoided, the sealing performance is improved, meanwhile, the stability of the tank cover in placement is improved through the outer end bolt, the first filter screen is clamped in the clamping ring, the first filter screen and the elastic piece are repeatedly and elastically matched with the vibration of the external micro vibrator, the filter screen is repeatedly moved up and down, and the large-particle medicine powder on the filter screen is oscillated, so that the blocking phenomenon of the filter screen caused by medicine particles is avoided.
According to the utility model, the fixing block is arranged to be matched with the annular groove, so that the first filter screen is stably placed, then the limiting procedure is completed by rotating inwards, the first filter screen is prevented from falling off in the vibration filtering process, the elastic piece is connected to the bottom of the fixing block, the first filter screen is embedded in the annular groove through the fixing block, then the first filter screen rotates inwards to move, the elastic piece is abutted against the first filter screen, and the first filter screen is matched with the external micro-vibrator to be processed in an up-down vibration mode, so that the filter screen is prevented from being blocked by drug particles, and the filtering rate of a medicament and the quality of filtrate are improved.
Drawings
FIG. 1 is a schematic perspective view of the present utility model;
FIG. 2 is a schematic elevational view of the present utility model;
FIG. 3 is a schematic view of a split three-dimensional structure of a fastener according to the present utility model;
FIG. 4 is a schematic view showing a split three-dimensional structure of a fitting member according to the present utility model;
Fig. 5 is a schematic view showing a split perspective structure of the filtering mechanism of the present utility model.
Legend description: 1. a fitting member; 101. a tank body; 102. a collar; 103. a gasket; 104. a seal ring; 105. a micro vibrator; 2. a filtering mechanism; 201. a fixing ring; 202. a ring groove; 203. a first filter screen; 204. a fixed block; 205. an elastic member; 3. a clamping piece; 301. a fixed rod; 302. a clamping groove; 303. a second filter screen; 4. a top cover; 401. a can lid; 402. a feed inlet; 403. a motor; 404. a stirring rod; 405. a fork knife.
Detailed Description
Referring to fig. 1, the present utility model provides a technical solution: the utility model provides a bio-pharmaceuticals separation purification filter equipment, includes laminating piece 1, filtering mechanism 2, block piece 3 and top cap 4, and the inside middle-end of laminating piece 1 is provided with filtering mechanism 2, and filtering mechanism 2's bottom is provided with block piece 3, and laminating piece 1's top is provided with top cap 4.
The specific arrangement and function of the fitting member 1, the filter mechanism 2, the engaging member 3 and the top cover 4 will be described in detail below.
Referring to fig. 1 to 3, in this embodiment: the top cap 4 includes cover 401, pan feeding mouth 402, motor 403, puddler 404 and fork type sword 405, and top one side of cover 401 is provided with pan feeding mouth 402, the top middle part of cover 401 is provided with motor 403, and the bottom of motor 403 is provided with puddler 404, the avris of puddler 404 is provided with fork type sword 405, be connected between puddler 404 and the fork type sword 405, and be rotatory connection between motor 403 and the puddler 404, throw into jar body 101 with the liquid medicine through pan feeding mouth 402, the surface of puddler 404 has the screw thread cutter then, simultaneously at its puddler 404's external surface mounting has detachable fork type sword 405, through being connected with motor 403, stir the liquid medicine on the first filter screen 203 afterwards, effectively increase the mobility of liquid medicine, be convenient for high-efficient flowing back, and fork type sword 405 can be the screw thread splice along puddler 404, be convenient for the later stage to the dismouting maintenance of fork type sword 405, the block 3 includes dead lever 301, draw-in groove 302 and second 303, and the bottom of dead lever 301 is provided with draw-in groove 302, the draw-in groove 302 has, the surface mounting groove has the screw thread cutter, install detachable filter sword 405 at the outside surface mounting at its puddler 404 installs detachable fork type sword 405, the second filter screen size is also can be changed for the second filter screen 302 simultaneously, the large-size is convenient for the filter screen is realized in the filter device, the filter granule is simultaneously to be changed in the large-size, the filter screen 303 is convenient for the filter device.
Referring to fig. 4 to 5, in this embodiment: the fitting piece 1 comprises a tank body 101, a clamping ring 102, a gasket 103, a sealing ring 104 and a micro vibrator 105, the middle part of the tank body 101 is provided with the clamping ring 102, the gasket 103 is arranged in the clamping ring 102, the sealing ring 104 is arranged on the side of the gasket 103, the micro vibrator 105 is arranged at the bottom of the outer side of the clamping ring 102, the top cover 4 and the tank body 101 form a clamping structure through the clamping ring 102, and the top cover 4 and the gasket 103 are tightly fitted, the clamping ring 102 matched with the bottom end of the tank cover 401 is arranged at the top end of the tank body 101, so that the tank cover 401 is conveniently clamped at the top end of the tank body 101, the gasket 103 and the sealing ring 104 are arranged in the clamping ring 102, the double sealing treatment is carried out, the reaction effect is avoided, the sealing performance is improved, meanwhile, the stability of the tank cover 401 is increased through an outer end bolt is improved, the clamping ring groove 203 is arranged in the clamping ring groove 102, the inner side is matched with the vibration of the external micro vibrator 105, the first filter 203 and an elastic piece 205 repeatedly and repeatedly move up and down, so that large particle medicine powder on the filter mesh is prevented from vibrating, the medicine particles on the filter mesh is prevented from blocking the filter 2, the filter 203 comprises a ring block 205, a ring 203 and a ring groove 204 are fixedly arranged at the bottom of the filter 203 and a ring groove 204, and a ring groove 204 are fixedly arranged on the filter 203, and a fixed structure, and a ring groove 204 is fixedly arranged on the top of the filter 203, and a ring groove 204, the limiting procedure is completed by internal rotation, the first filter screen 203 is prevented from falling off in the vibration filtering process, the elastic piece 205 is connected to the bottom of the fixing block 204, the first filter screen 203 is embedded in the annular groove 202 through the fixing block 204, then the first filter screen is rotated to move inwards, the elastic piece 205 is abutted against the first filter screen, the external micro-vibrator 105 is matched to process the first filter screen in an up-and-down vibration mode, the filter screen is prevented from being blocked by drug particles, and the filtering rate of the medicament and the quality of filtrate are improved.
According to the working principle, firstly, the bottom of a fixed block 204 is connected with an elastic piece 205, a first filter screen 203 is embedded in a ring groove 202 through the fixed block 204, then rotates to move inwards, is tightly supported and installed by the elastic piece 205, and then a clamping ring 102 matched with the bottom end of a tank cover 401 is arranged at the top end of the tank body 101, so that the tank cover 401 is conveniently clamped at the top end of the tank body 101, and the tank body 101 is installed;
Secondly, the liquid medicine is put into the tank body 101 through the feed inlet 402, then the surface of the stirring rod 404 is provided with a threaded cutter, and meanwhile, the external surface of the stirring rod 404 is provided with a detachable fork-shaped cutter 405, and the detachable fork-shaped cutter 405 is connected with the motor 403 to stir the liquid medicine on the first filter screen 203, so that the liquid medicine is conveniently and efficiently discharged, and the fork-shaped cutter 405 can be spliced along the stirring rod 404 in a threaded manner, so that the fork-shaped cutter 405 can be conveniently disassembled, assembled and maintained in the later stage;
And finally, the size of the second filter screen 303 at the bottom is the same as that of the clamping groove 302, so that the second filter screen 303 is embedded in the clamping groove 302, the subsequent disassembly and replacement are convenient, and the inside of the separation and purification filter device is provided with a double-filter structure, so that the liquid medicine can be effectively removed from large particles in the separation engineering.
In the description of the present utility model, it should be noted that, unless explicitly specified and limited otherwise, the terms "mounted," "connected," and "connected" are to be construed broadly, and may be either fixedly connected, detachably connected, or integrally connected, for example; can be mechanically or electrically connected; can be directly connected or indirectly connected through an intermediate medium, and can be communication between two elements. The specific meaning of the above terms in the present utility model can be understood by those of ordinary skill in the art in a specific case.
Claims (7)
1. The utility model provides a bio-pharmaceuticals separation purification filter equipment, includes laminating piece (1), filtering mechanism (2), block piece (3) and top cap (4), its characterized in that: the inside middle-end of laminating piece (1) is provided with filtering mechanism (2), and filtering mechanism's (2) bottom is provided with fastener (3), laminating piece's (1) top is provided with top cap (4), filtering mechanism (2) are including solid fixed ring (201), annular (202), first filter screen (203), fixed block (204) and elastic component (205), and gu the inside of fixed ring (201) is provided with annular (202), gu the top of fixed ring (201) is provided with first filter screen (203), and the both sides of first filter screen (203) are provided with fixed block (204), the bottom of fixed block (204) is provided with elastic component (205).
2. The biopharmaceutical separation and purification filter device according to claim 1, wherein: the first filter screen (203) and the fixed ring (201) form a clamping structure through the fixed block (204), and the fixed block (204) and the ring groove (202) form an elastic structure through the elastic piece (205).
3. The biopharmaceutical separation and purification filter device according to claim 1, wherein: the clamping piece (3) comprises a fixing rod (301), a clamping groove (302) and a second filter screen (303), the clamping groove (302) is formed in the bottom end of the fixing rod (301), and the second filter screen (303) is arranged at the top end of the clamping groove (302).
4. The biopharmaceutical separation and purification filter device according to claim 1, wherein: top cap (4) are including cover (401), pan feeding mouth (402), motor (403), puddler (404) and fork type sword (405), and top one side of cover (401) is provided with pan feeding mouth (402), the top middle part of cover (401) is provided with motor (403), and the bottom of motor (403) is provided with puddler (404), the avris of puddler (404) is provided with fork type sword (405).
5. The biopharmaceutical separation and purification filter device according to claim 4, wherein: the stirring rod (404) is connected with the fork-shaped knife (405), and the motor (403) is in rotary connection with the stirring rod (404).
6. The biopharmaceutical separation and purification filter device according to claim 1, wherein: fitting piece (1) is including jar body (101), rand (102), packing ring (103), sealing washer (104) and miniature bobbing machine (105), and the middle part of jar body (101) is provided with rand (102), the inside of rand (102) is provided with packing ring (103), and the avris of packing ring (103) is provided with sealing washer (104), the outside bottom of rand (102) is provided with miniature bobbing machine (105).
7. The biopharmaceutical separation and purification filter device according to claim 6, wherein: the top cover (4) and the tank body (101) form a clamping structure through the clamping ring (102), and the top cover (4) and the gasket (103) are tightly attached.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202322251834.7U CN220802326U (en) | 2023-08-22 | 2023-08-22 | Separation and purification filter device for biopharmaceuticals |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202322251834.7U CN220802326U (en) | 2023-08-22 | 2023-08-22 | Separation and purification filter device for biopharmaceuticals |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN220802326U true CN220802326U (en) | 2024-04-19 |
Family
ID=90674800
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202322251834.7U Active CN220802326U (en) | 2023-08-22 | 2023-08-22 | Separation and purification filter device for biopharmaceuticals |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN220802326U (en) |
-
2023
- 2023-08-22 CN CN202322251834.7U patent/CN220802326U/en active Active
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