CN220709175U - Target object detection device and body - Google Patents
Target object detection device and body Download PDFInfo
- Publication number
- CN220709175U CN220709175U CN202322316076.2U CN202322316076U CN220709175U CN 220709175 U CN220709175 U CN 220709175U CN 202322316076 U CN202322316076 U CN 202322316076U CN 220709175 U CN220709175 U CN 220709175U
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- porous carrier
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- collector
- object detection
- chamber
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- 238000001514 detection method Methods 0.000 title claims abstract description 75
- 238000012360 testing method Methods 0.000 claims abstract description 53
- 238000010521 absorption reaction Methods 0.000 claims abstract description 27
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- 239000003814 drug Substances 0.000 claims abstract description 6
- 239000012528 membrane Substances 0.000 claims description 24
- 238000006243 chemical reaction Methods 0.000 claims description 23
- 238000001914 filtration Methods 0.000 claims description 20
- 238000007789 sealing Methods 0.000 claims description 11
- 230000008878 coupling Effects 0.000 claims 1
- 238000010168 coupling process Methods 0.000 claims 1
- 238000005859 coupling reaction Methods 0.000 claims 1
- 238000000034 method Methods 0.000 abstract description 16
- 230000010354 integration Effects 0.000 abstract description 4
- 238000001125 extrusion Methods 0.000 abstract description 2
- 210000003296 saliva Anatomy 0.000 description 20
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- 239000002250 absorbent Substances 0.000 description 5
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- 102000009027 Albumins Human genes 0.000 description 4
- 108010088751 Albumins Proteins 0.000 description 4
- 239000008280 blood Substances 0.000 description 4
- 210000004369 blood Anatomy 0.000 description 4
- 230000035935 pregnancy Effects 0.000 description 4
- 239000004094 surface-active agent Substances 0.000 description 4
- 210000002700 urine Anatomy 0.000 description 4
- 239000004382 Amylase Substances 0.000 description 3
- 201000010099 disease Diseases 0.000 description 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 3
- 102000013142 Amylases Human genes 0.000 description 2
- 108010065511 Amylases Proteins 0.000 description 2
- 229920002472 Starch Polymers 0.000 description 2
- 235000019418 amylase Nutrition 0.000 description 2
- 238000004458 analytical method Methods 0.000 description 2
- 238000003745 diagnosis Methods 0.000 description 2
- 239000012535 impurity Substances 0.000 description 2
- 229920002521 macromolecule Polymers 0.000 description 2
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- 235000019698 starch Nutrition 0.000 description 2
- 210000004243 sweat Anatomy 0.000 description 2
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- 102000003886 Glycoproteins Human genes 0.000 description 1
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Landscapes
- Investigating Or Analysing Biological Materials (AREA)
Abstract
The utility model discloses a target detection device and a body, which belong to the technical field of biological detection, and comprise a collector and a body, wherein the body comprises a shell, a porous carrier and a test element, the porous carrier is used for storing medicaments, the shell is hollow, the shell is provided with a connecting port and a detection cavity, the porous carrier is arranged in the shell and positioned between the connecting port and the detection cavity, the test element is positioned in the detection cavity, the collector comprises a collection handle and an absorption element connected with the collection handle, the absorption element is used for absorbing a liquid sample, the absorption element is positioned in the shell and is abutted against the porous carrier, so that the liquid sample absorbed by the absorption element flows into the porous carrier and is mixed with the medicaments in the porous carrier, and the test element detects the mixed liquid. The sample that this application was through simple rotating collector extrusion absorption element to gathering carries out preliminary treatment to realize sample collection and target object detection integration, testing process convenient and fast.
Description
Technical Field
The utility model relates to the technical field of biological detection, in particular to a target object detection device and a body.
Background
Human Chorionic Gonadotrophin (HCG) is a glycoprotein hormone secreted by placenta-derived trophoblasts and having a relative molecular weight of 36700Da. The detection of HCG has great significance for early pregnancy diagnosis and monitoring of women after abortion, and has certain value for diagnosis, identification, disease course observation and the like of pregnancy related diseases, trophoblast tumors and other diseases.
Human body includes blood, urine, saliva, sweat and various excretions, and HCG detection is currently mainly performed in both blood and urine. In the blood detection and urine detection processes, firstly, sampling is needed, the sample is transferred to a detection chamber after sampling, a small amount of sample is dripped on test paper in the detection chamber through an instrument, the whole process is complex in operation, and pollution risks exist.
Disclosure of Invention
In order to overcome the defects of the prior art, the utility model aims to provide a target object detection device and a body, wherein the detection device can realize integration of sample collection and target object detection, and the detection process is convenient and quick.
The utility model adopts the following technical scheme:
the utility model provides a target detection device, includes collector and body, the body includes casing, porous carrier and test element, porous carrier is used for storing the medicament, the inside cavity of casing, the casing is equipped with connector and detection chamber, porous carrier installs in the casing and be located the connector with detect between the chamber, test element is located detect the intracavity, the collector include gather the handle and with the absorbing element that gathers the handle and be connected, absorbing element is used for absorbing liquid sample, absorbing element is located in the casing and with porous carrier contradicts, makes absorbing element absorbing liquid sample inflow porous carrier and with medicament in the porous carrier mixes, test element detects mixed liquid.
Further, the collector also comprises a connecting column, and the absorption element is connected with the collecting handle through the connecting column.
Further, the outer wall of the connecting port is provided with an external thread, the inner wall of the collecting handle is provided with an internal thread, and the external thread is matched with the internal thread to enable the collector to be connected with the body.
Further, the collector also comprises a sealing ring, and the sealing ring is positioned between the shell and the collecting handle.
Further, the shell is further provided with a collecting cavity and a flow cavity, the porous carrier is installed at the tail end of the collecting cavity, at least one flow port is arranged below the flow cavity, and the upper surface of one end of the test element is opposite to the flow port below the flow cavity.
Further, the body further comprises a reaction carrier and a filtering membrane, wherein the reaction carrier and the filtering membrane are installed in the shell, and the filtering membrane is located between the reaction carrier and the flow cavity.
Further, the test element is a test strip.
Further, the shell is further provided with a viewing window, the viewing window is located on the upper surface of the shell, and the viewing window is opposite to the test element in position.
Further, the body is inserted with the collector.
A body comprising a housing, characterized in that: the body still includes porous carrier, reaction carrier, filtration membrane and test element, the casing is equipped with connector, collection chamber, flow chamber and detection chamber in proper order, porous carrier installs in the casing and be located the connector with detect between the chamber, test element is located detect the intracavity, flow chamber below is equipped with at least one and flows the mouth, test element one end upper surface with the flow mouth of flow chamber below is relative, test element is the test paper strip, reaction carrier with filtration membrane installs in the casing, filtration membrane is located reaction carrier with flow between the chamber.
The utility model has the beneficial effects that:
1. the detection device comprises the collector, the absorption element is immersed or contained in the mouth by holding the collection handle to collect the body fluid sample, so that the collection process of the body fluid sample is simple, convenient and quick, and meanwhile, the sealing ring is added between the collection handle and the absorption element to prevent the liquid sample from flowing back during the body fluid detection process, so that the detection process is clean and pollution-free;
2. the detection device comprises a porous carrier, a reaction carrier and a filtering membrane, wherein the absorption element is extruded by a simple rotation collector to pretreat the collected saliva sample and effectively filter impurities in saliva, so that the detectability of analytes in a body fluid sample is improved;
3. the detection device provided by the utility model has the advantages that the detection cavity contains the test element, and the preprocessed saliva sample directly flows into the test element through the flow cavity, so that the integration of sample collection and target object detection is realized, the detection process is convenient and quick, and a simple, convenient and reliable mode is provided for home self-detection of early pregnancy users.
Drawings
FIG. 1 is a schematic diagram of an object detection device and a body overall structure according to the present utility model;
FIG. 2 is a front view of a target detection apparatus and a body harvester according to the present utility model;
FIG. 3 is a cross-sectional view of a target detection apparatus and a body according to the present utility model;
FIG. 4 is a partial enlarged view of a target object detection device and a body filtering membrane according to the present utility model;
FIG. 5 is a top view of a target detection device and a body detection chamber according to the present utility model;
FIG. 6 is a cross-sectional view of a target detection apparatus and a body according to the present utility model in an inserted state;
FIG. 7 is a cross-sectional view of an object detection device and a body in a tightened state according to the present utility model;
in the figure: 10. a collector; 11. a collecting handle; 12. a connecting column; 13. a seal ring; 14. an absorbent member; 20. a body; 21. a housing; 211. a connection port; 212. a collection chamber; 213. a flow chamber; 214. a detection chamber; 215. an observation window; 22. a porous support; 23. a reaction carrier; 24. a filtering membrane; 25. and testing the element.
Detailed Description
The following description of the embodiments of the present utility model will be made clearly and completely with reference to the accompanying drawings, in which it is apparent that the embodiments described are only some embodiments of the present utility model, but not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the utility model without making any inventive effort, are intended to be within the scope of the utility model.
It will be understood that when an element is referred to as being "fixed to" another element, it can be directly on the other element or be present as another intermediate element through which the element is fixed. When an element is referred to as being "connected" to another element, it can be directly connected to the other element or intervening elements may also be present. When an element is referred to as being "disposed on" another element, it can be directly on the other element or intervening elements may also be present. The terms "vertical," "horizontal," "left," "right," and the like are used herein for illustrative purposes only.
Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this utility model belongs. The terminology used herein in the description of the utility model is for the purpose of describing particular embodiments only and is not intended to be limiting of the utility model. The term "and/or" as used herein includes any and all combinations of one or more of the associated listed items.
Fig. 1 to 7 show a target object detection device according to the present utility model, which includes a collector 10 and a body 20.
The collector 10 is used for collecting liquid samples including blood, urine, saliva, sweat and various exudates, and also includes liquid solutions formed by pre-treating solid samples and semi-solid samples. The sample of the present utility model is a saliva sample. The body 20 is used for preprocessing the liquid sample collected by the collector 10 and detecting the preprocessed liquid sample.
The harvester 10 comprises a harvesting handle 11, a connecting column 12, a sealing ring 13 and an absorbing element 14.
The absorption element 14 is connected with the collection handle 11 through the connecting column 12, and the collection handle 11 is a rigid piece, so that the operation of the absorption element 14 is facilitated. Specifically, the collection handle 11 is made of plastic, wood, metal and other materials, so that an operator can conveniently operate the collector 10, wherein the collection handle 11 is internally threaded. In this embodiment, the absorbent member 14 is made of a medical grade sponge or foam as is commonly used in the art, and the absorbent member 14 is immersed in the sample or placed in the mouth to collect the sample during use. In other embodiments, the absorbent member 14 is a material having absorbent properties, such as cotton or paper.
The sealing ring 13 is located between the collection handle 11 and the absorption element 14, and the sealing ring 13 surrounds the connection part between the collection handle 11 and the absorption element 14, and is used for sealing the collection cavity 212, preventing the liquid sample from flowing back to the collection handle 11 in the process of rotary extrusion, and simultaneously enabling the collection sample in the absorption element 14 to be extruded more thoroughly. In this embodiment, the cross-sectional shape of the seal ring 13 is O-shaped. In other embodiments, the cross-sectional shape of the seal ring 13 may be matched to the junction.
Body 20 includes a housing 21, a porous support 22, a reaction support 23, a filtration membrane 24, and a test element 25. Porous support 22, reaction support 23, filtration membrane 24, and test element 25 are located within housing 21.
The housing 21 is provided with a connection port 211, a collection chamber 212, a flow chamber 213, a detection chamber 214, and an observation window 215. The connection port 211, the collection cavity 212, the flow cavity 213 and the detection cavity 214 are positioned in the shell 21, the observation window 215 is positioned on the upper surface of the shell 21, the porous carrier 22 and the reaction carrier 23 are arranged between the collection cavity 212 and the flow cavity 213, and the detection cavity 214 is communicated with the flow cavity 213 through a flow port below the flow cavity 213.
The external thread of the outer wall of the connecting port 211 is consistent with the internal thread of the inner wall of the collecting handle 11 in size, and the body 20 is in spiral connection with the collector 10, so that the collector 10 enters the collecting cavity 212. In other embodiments, the body 20 is plugged with the collector 10.
Positioned within the collection chamber 212 is a porous carrier 22, the porous carrier 22 being made of a porous sponge or porous foam material; the porous carrier 22 accommodates therein freeze-dried powder of albumin, surfactant and the like, and the liquid sample is caused to flow through the porous carrier 22 by squeezing the absorption element 14 by rotating the collection handle 11, so that the albumin, surfactant and the like are introduced into the sample, thereby eliminating nonspecific adsorption, improving sample fluidity, and making the subsequent detection result more obvious.
The reaction carrier 23 is located between the porous carrier 22 and the filtering membrane 24, and the reaction carrier 23 can contain starch, diluent (sealed by sealing membranes at two ends of the reaction carrier 23), and the like, and is used for combining with salivary amylase in saliva or diluting a liquid sample, so that the detectability of an analyte in the sample is improved.
The filter membrane 24 is made of Polyethersulfone (PES), polytetrafluoroethylene (PTFE), nylon (PA 66), or the like, and is used for removing macromolecular substances from a liquid sample.
Preferably, the pore size of filter membrane 24 is 0.2-0.8. Mu.m.
At least one flow port is provided below the flow chamber 213, which directs the pretreated sample into the detection chamber 214.
The detection chamber 214 is a chamber for receiving the test element 25 and allowing the liquid sample to enter the detection chamber 214 through the flow chamber 213 to contact the test element 25 for detection. The shape is varied and the shape and number of the test elements 25 to be accommodated are designed according to the need. In this embodiment, the test element 25 is a test strip, and the test strip for analyzing an analyte in a sample is in various forms, such as immunoassay or chemical analysis. The test paper adopts an analysis mode of a non-competition method or a competition method. Typical non-competitive assay formats are: if the sample contains an analyte, a signal is generated, and if the sample does not contain an analyte, no signal is generated. In competition methods, a signal is generated if the analyte is not present in the sample, and no signal is generated if the analyte is present. The various zones of the test strip are arranged in the following manner: the device comprises a sample receiving area, a reagent area, a detection area, a control area and a liquid sample absorbing area. The control zone is located behind the detection zone. All of the zones are arranged on a strip of paper of only one material. Different materials may be used for the different regions. Each zone is in direct contact with the liquid sample, or the different zones are arranged according to the direction of flow of the liquid sample, and the end of each zone is connected with the front end of the other zone and overlapped. The material is a material with better water absorption, such as filter paper, glass fiber or nitrocellulose membrane, etc. In other preferred embodiments, the test strip takes other forms, one or more of the test elements 25, and a plurality of the test elements 25 each detect a different analyte in the sample.
In a preferred embodiment, a detection window 215 is provided in the detection chamber 214, where the window corresponds to the detection area of the test strip, so as to facilitate observation of the detection result of the test strip. Alternatively, in other embodiments detection chamber 214 itself is transparent to facilitate viewing the test results of the test strip.
When the saliva sample collection device is used, firstly, the collection handle 11 is held by hand, the absorption element 14 is contained in the mouth to collect the saliva sample, then the collector 10 is inserted into the body 20, the absorption element 14 is inserted into the collection cavity 212, the collection handle 11 is rotated, the absorption element 14 and the porous carrier 22 are sequentially compressed, the saliva sample flows through the porous carrier 22, albumin and the surfactant are dissolved in the saliva sample, the albumin and the surfactant are introduced into the saliva sample, then the liquid flows through the reaction carrier 23, starch in the reaction carrier 23 is combined with salivary amylase in the saliva sample, then the saliva sample flows through the filtering membrane 24, macromolecular substances in saliva and starch-amylase combination are filtered, finally the pretreated saliva sample flows to the test strip in the detection cavity 214 through the flow cavity 213, the target in saliva is specifically identified, and the test result is observed through the observation window 215.
The utility model immerses or contains the absorption element 14 in the mouth to collect the body fluid sample by holding the collection handle 11, so that the collection process of the body fluid sample is simple, convenient and quick, and meanwhile, the sealing ring 13 is added between the collection handle 11 and the absorption element 14 to prevent the liquid sample from flowing back during the body fluid detection process, so that the detection process is clean and pollution-free; the collected saliva sample is pretreated by simply rotating the collector 10 to squeeze the absorption element 14 and utilizing the porous carrier 22, the reaction carrier 23 and the filtering membrane 24, and impurities in saliva are effectively filtered, so that the detectability of analytes in the body fluid sample is improved; the detection cavity 214 contains the test element 25, and the preprocessed saliva sample directly flows into the test element 25 through the flow cavity 213, so that the integration of sample collection and target object detection is realized, the detection process is convenient and quick, and a simple, convenient and reliable mode is provided for home self-detection of early pregnancy users.
The foregoing examples illustrate only a few embodiments of the utility model, which are described in detail and are not to be construed as limiting the scope of the utility model. It should be noted that, for those skilled in the art, it is possible to make several modifications and improvements without departing from the concept of the present utility model, which are equivalent to the above embodiments according to the essential technology of the present utility model, and these are all included in the protection scope of the present utility model.
Claims (10)
1. The utility model provides a target object detection device, includes collector and body, its characterized in that: the body includes casing, porous carrier and test element, porous carrier is used for storing the medicament, the inside cavity of casing, the casing is equipped with connector and detection chamber, porous carrier installs in the casing and be located the connector with detect between the chamber, test element is located detect the intracavity, the collector include gather the handle and with gather the absorption element that the handle is connected, absorption element is used for absorbing liquid sample, absorption element is located in the casing and with porous carrier contradicts, makes absorption element absorbing liquid sample inflow porous carrier and with medicament in the porous carrier mixes, test element detects mixed liquid.
2. The object detection device according to claim 1, wherein: the collector also comprises a connecting column, and the absorption element is connected with the collecting handle through the connecting column.
3. The object detection device according to claim 1, wherein: the connector outer wall is equipped with the external screw thread, collection handle inner wall is equipped with the internal screw thread, the external screw thread with the internal screw thread cooperation makes the collector with body coupling.
4. The object detection device according to claim 1, wherein: the collector also comprises a sealing ring, and the sealing ring is positioned between the shell and the collecting handle.
5. The object detection device according to claim 1, wherein: the shell is also provided with a collecting cavity and a flow cavity, the porous carrier is arranged at the tail end of the collecting cavity, at least one flow port is arranged below the flow cavity, and the upper surface of one end of the test element is opposite to the flow port below the flow cavity.
6. The object detection device according to claim 5, wherein: the body also comprises a reaction carrier and a filtering membrane, wherein the reaction carrier and the filtering membrane are installed in the shell, and the filtering membrane is positioned between the reaction carrier and the flow cavity.
7. The object detection device according to claim 1, wherein: the test element is a test strip.
8. The object detection device according to claim 1, wherein: the shell is also provided with an observation window, the observation window is positioned on the upper surface of the shell, and the observation window is opposite to the test element in position.
9. The object detection device according to claim 1, wherein: the body is inserted between the collector and the collector.
10. A body comprising a housing, characterized in that: the body still includes porous carrier, reaction carrier, filtration membrane and test element, the casing is equipped with connector, collection chamber, flow chamber and detection chamber in proper order, porous carrier installs in the casing and be located the connector with detect between the chamber, test element is located detect the intracavity, flow chamber below is equipped with at least one and flows the mouth, test element one end upper surface with the flow mouth of flow chamber below is relative, test element is the test paper strip, reaction carrier with filtration membrane installs in the casing, filtration membrane is located reaction carrier with flow between the chamber.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202322316076.2U CN220709175U (en) | 2023-08-28 | 2023-08-28 | Target object detection device and body |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202322316076.2U CN220709175U (en) | 2023-08-28 | 2023-08-28 | Target object detection device and body |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN220709175U true CN220709175U (en) | 2024-04-02 |
Family
ID=90451055
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202322316076.2U Active CN220709175U (en) | 2023-08-28 | 2023-08-28 | Target object detection device and body |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN220709175U (en) |
-
2023
- 2023-08-28 CN CN202322316076.2U patent/CN220709175U/en active Active
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