CN219557387U - Nasal mucosa epithelial cell curet - Google Patents

Nasal mucosa epithelial cell curet Download PDF

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Publication number
CN219557387U
CN219557387U CN202320415748.2U CN202320415748U CN219557387U CN 219557387 U CN219557387 U CN 219557387U CN 202320415748 U CN202320415748 U CN 202320415748U CN 219557387 U CN219557387 U CN 219557387U
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cup
epithelial cell
nasal mucosa
nasal
curet
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CN202320415748.2U
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丛铁川
秦永
王全桂
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Peking University First Hospital
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Peking University First Hospital
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    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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Abstract

The utility model discloses a nasal mucosa epithelial cell curet, which comprises the following components: a holding part for facilitating the holding of an operator; a material drawing part connected with the front end of the holding part; the cup-shaped part is arranged at the free end of the material drawing part and used for scraping and holding nasal mucosa epithelial cells, and the top of the cup-shaped part protrudes from the material drawing part. The nasal mucosa epithelial cell curet has the advantages of simple structure, convenient and quick use, more direct and accurate material taking, simple and time-saving material transferring step, little uncomfortable feeling to patients, good material taking repeatability and more obtained cell quantity compared with the prior method.

Description

Nasal mucosa epithelial cell curet
Technical Field
The utility model relates to the technical field of medical treatment, in particular to a nasal mucosa epithelial cell curet.
Background
The current domestic method for obtaining nasal mucosa epithelial cells comprises the following steps: nasal irrigation, filter paper or filter block sampling, cytobrush sampling, and the like. Among other things, nasal wash solutions can evaluate proteins, cells, cytokines, etc. in nasal secretions, but cannot be considered a "gold standard" method of cytologically sampling, since the sampled cells are typically in an apoptotic state. Filter paper or filter block sampling is highly reproducible, but it requires a well-equipped laboratory to process and read the sample, adding to the cost and time to obtain the results. Nasal cell brushes (such as the nasal mucosa epithelial cell brush of patent number CN 211559099U) can provide information of living epithelial cells of nasal mucosa, and have certain advantages compared with nasal cavity flushing, and are generally used for researching ultrastructures of epithelial cilia, however, the nasal mucosa epithelial cells of a patient are brushed by adopting a brush, discomfort is easily caused to the patient, and sampling and transferring treatment of the epithelial cells brushed on the brush are relatively troublesome.
Disclosure of Invention
The utility model aims to solve the problems, and provides the nasal mucosa epithelial cell curet which is simple in structure, convenient and quick to use, more direct and accurate in material taking, simple and time-saving in material transferring step, almost free of discomfort to a patient, good in material taking repeatability and more in obtained cell quantity than the existing method.
In order to achieve the above object, the present utility model provides a nasal mucosa epithelial cell curet comprising: a holding part for facilitating the holding of an operator; a material drawing part connected with the front end of the holding part; the cup-shaped part is arranged at the free end of the material drawing part and used for scraping and holding nasal mucosa epithelial cells, and the top of the cup-shaped part protrudes from the material drawing part.
Preferably, the cup-shaped part is a cup body which is open at the top and is in a straight cylindrical shape or a conical cylindrical shape, and the top edge of the cup body is sharp.
Preferably, the bottom of the cup-shaped part is fixedly connected with the upper surface of the free end of the material drawing part, and the central axis of the cup-shaped part is perpendicular to the length extending direction of the material drawing part.
Preferably, the material taking part is a flat rod.
Preferably, the flat bar width is gradually narrowed.
Preferably, the grip portion is an elongate flat bar.
Further, the device also comprises a transition part which is positioned between the holding part and the material drawing part and is respectively connected with the two ends in an inclined way.
Preferably, an included angle of 150-160 degrees is formed between the transition part and the holding part, and an included angle of 145-155 degrees is formed between the transition part and the material drawing part.
Preferably, the upper surface of the material taking part is a concave arc surface.
Preferably, the diameter of the top opening of the cup-shaped part is 1.5mm-2.5mm, and the depth is 0.4mm-1.2mm.
Compared with the prior art, the nasal mucosa epithelial cell curet has the following advantages:
1. the nasal mucosa epithelial cell curet has the advantages of simple structure, convenient and quick use, more direct and accurate material taking, simple and time-saving material transferring step, little uncomfortable feeling for patients, good material taking repeatability and more obtained cell quantity compared with the prior method.
2. According to the nasal mucosa epithelial cell curet, the top of the cup-shaped part protrudes from the material taking part, so that an operator can directly observe the nasal cavity of a patient when taking materials conveniently, and the sharp top edge of the cup-shaped part is utilized to scrape the nasal mucosa epithelial cells of the patient, so that the materials can be obtained more directly and accurately, the scraped epithelial cells fall into the cup-shaped part, the collection is convenient, the transfer of the materials is convenient, the operation of each step is simple, the time is saved, the workload of medical staff is reduced, the efficiency is high, and the repeated use is convenient.
The present utility model will be described in detail with reference to the accompanying drawings.
Drawings
FIG. 1 is a perspective view of a first construction of a nasal mucosal epithelial cell curet according to the utility model;
FIG. 2 is a front view of a first construction of the nasal mucosa epithelial cell curet of the utility model;
FIG. 3 is a top view of a first construction of the nasal mucosal epithelial cell curet of the utility model;
fig. 4 is an enlarged view of a portion a in fig. 1;
fig. 5 is an enlarged view of a portion B in fig. 1;
FIG. 6 is a perspective view of a second construction of the nasal mucosal epithelial cell curet of the utility model;
FIG. 7 is a front view of a second construction of the nasal mucosal epithelial cell curet of the utility model;
FIG. 8 is a top view of a second construction of the nasal mucosal epithelial cell curet of the utility model;
fig. 9 is an enlarged view of a portion a in fig. 6;
FIG. 10 is a perspective view of a third construction of a nasal mucosal epithelial cell curet according to the utility model;
fig. 11 is an enlarged view of a portion a in fig. 10.
Detailed Description
As shown in fig. 1 to 3, fig. 6 to 8, and fig. 10, which are respectively schematic structural diagrams of different structures of the nasal mucosa epithelial cell curettage device provided by the present utility model, it can be seen that the nasal mucosa epithelial cell curettage device of the present utility model includes: a grip portion 1 for facilitating the grip of an operator; a material drawing part 2 connected with the front end of the holding part; the cup-shaped part is arranged at the free end of the material drawing part and used for scraping and holding nasal mucosa epithelial cells, and the top of the cup-shaped part protrudes from the material drawing part 3. The cup-shaped part is a cup body with an opening at the top and a straight or cone-shaped shape, the top edge of the cup-shaped part is sharp, the diameter of the opening at the top of the cup-shaped part is 1.5mm-2.5mm, and the depth of the opening at the top of the cup-shaped part is 0.4mm-1.2mm.
According to the nasal mucosa epithelial cell curet, an operator holds the holding part by hand, the front end of the material taking part extends into the middle lower part of the lower nasal concha hung by a patient, the nasal mucosa epithelial cells of the patient can be scraped and taken directly by the cup-shaped part, the convenience of material taking and the number and quality of the taken epithelial cells are improved, the discomfort of the patient is reduced, the collection is convenient, the transfer of the taken materials is convenient, the operation of each step is simple and time-saving, the workload of medical staff is reduced, and the efficiency is high.
The structure of the nasal mucosa epithelial cell curet according to the present utility model will be described in detail with reference to the following examples.
Example 1
As shown in fig. 1 to 3, the schematic diagrams of different structures of the nasal mucosa epithelial cell curettage device according to the present embodiment are shown, and as can be seen from the diagrams, the nasal mucosa epithelial cell curettage device includes: a grip portion 1 for facilitating the grip of an operator; a material drawing part 2 connected with the front end of the holding part; the cup-shaped part is arranged at the free end of the material drawing part and used for scraping and holding nasal mucosa epithelial cells, and the top of the cup-shaped part protrudes from the material drawing part 3.
Specifically, the holding part 1 of this embodiment is an elongated flat rod, which may be a flat rod with a constant width (as shown in fig. 2 and 3), or a flat rod with a gradually narrowing or widening width (not shown), and may have a length of 55-65mm, a width of 4-8mm, and a height of 3-5mm. Preferably, in this embodiment, the length is 60mm, the width is 6mm, and the height is 4mm.
The rear end of the material taking part is fixedly connected with the front end of the holding part into a whole, the material taking part is also an elongated flat rod, the width of the rear end of the material taking part is the same as that of the front end of the holding part, and when the material taking part extends forwards, the width gradually narrows towards the center (as shown in figure 3). The length of the material taking part can be 70-75mm, the narrowest part of the width can be 1.5-3mm, and the smallest part of the height can be 0.5-1.5mm. Preferably, in this embodiment, the length of the material taking part is 72mm, the narrowest part (i.e. front end) of the width is 2mm, the smallest part (i.e. front end) of the height is 1mm, and the width and height of the rear end are the same as those of the holding part.
The upper surface of the sampling part is flush with the upper surface of the holding part, and the lower surface can be parallel to the upper surface or can be inclined upwards from back to front (as shown in fig. 2). The upper surfaces of the material drawing portion and the holding portion may be horizontal surfaces, or may be concave arc surfaces 4 (as shown in fig. 5) for the convenience of an operator to check the conditions in the nasal cavity of the patient.
In this embodiment, the bottom of the cup portion is fixedly connected with the upper surface of the free end of the material drawing portion, so that the cup portion protrudes from the upper surface of the material drawing portion, and the central axis of the cup portion is perpendicular to the length extending direction of the material drawing portion.
The cup-shaped part of the embodiment is a cup body (shown in fig. 4) with an opening at the top and a straight cylindrical shape, the diameter of the opening at the top of the cup body is 1.5mm-2.5mm, and the depth is 0.4mm-1.2mm. Preferably, the top opening of the cup in this embodiment has a diameter of 2.0mm and a depth of 0.6mm. The top edge of the cup body is sharp, so that nasal mucosa epithelial cells can be scraped by the top edge, and the epithelial cells fall into the cup body, so that the subsequent transfer and treatment are facilitated.
The inner wall of the cup body can be a vertical surface with a constant diameter, or the inner wall of the cup body can also be a slope surface gradually narrowed from the top of the cup to the bottom of the cup (namely, the inner wall of the cup body is a concave surface), so that epithelial cells can slide into the cup body along the slope surface, and the subsequent transfer and treatment are facilitated.
When designing, if the upper surfaces of the material taking part and the holding part adopt concave arc surfaces, the concave direction is consistent with the concave direction of the cup body.
When the nasal mucosa epithelial cell curet of the embodiment is adopted, under the direct visual inspection, an operator inserts a material drawing part and a cup part into the middle lower part of the lower nasal concha of a patient, enables an opening of the cup part to be propped against the mucosal surface of the middle lower part of the lower nasal concha, lightly presses the cup part to enable the cup part to be buckled on the mucosal surface, then moves outwards for 2-3 mm, repeats the actions for 2-3 times, and then adopts a subsequent medical instrument to transfer and process the epithelial cells collected in the cup body.
Example two
As shown in fig. 6 to 8, the schematic diagrams of different structures of the nasal mucosa epithelial cell curettage device according to the present embodiment are shown, and as can be seen from the diagrams, the nasal mucosa epithelial cell curettage device according to the present embodiment includes: a grip portion 1 for facilitating the grip of an operator; a material drawing part 2 connected with the front end of the holding part; the cup-shaped part is arranged at the free end of the material drawing part and used for scraping and holding nasal mucosa epithelial cells, and the top of the cup-shaped part protrudes from the material drawing part 3. In addition, the device also comprises a transition part 5 which is arranged between the holding part and the material drawing part and the two ends of which are respectively connected with the holding part and the material drawing part in an inclined way.
Specifically, the holding part 1 of this embodiment is a flat bar which is also elongated, has a constant width, has a length of 70mm, a width of 6mm, and a height gradually decreasing from rear to front, a rear end height of 8mm, and a front end height of 5mm.
The rear end of the transition part is obliquely connected with the front end of the holding part, an included angle of 150-160 degrees can be formed between the rear end surface (vertical end surface) of the transition part and the upper surface of the holding part, and preferably, an included angle of 155 degrees is formed between the transition part and the holding part. The transition part is also a flat rod, the width is the same as that of the holding part, the height of the rear end is the same as that of the holding part, the height of the front end is 3mm, and the length is 20mm.
The rear end of the material drawing part is obliquely connected with the front end of the transition part, an included angle of 145-155 degrees can be formed between the front end surface (vertical end surface) of the transition part and the upper surface of the material drawing part, and preferably, an included angle of 150 degrees is formed between the transition part and the material drawing part in the embodiment. The material sampling part is also an elongated flat rod, and the width gradually narrows towards the center when the material sampling part extends forwards (as shown in figure 8). The length of the material taking part can be 55-65mm, the narrowest part of the width can be 1.5-3mm, and the smallest part of the height can be 0.5-1.5mm. Preferably, in this embodiment, the length of the material taking part is 60mm, the narrowest part (i.e. front end) of the width is 2mm, the smallest part (i.e. front end) of the height is 1mm, and the width and height of the rear end are the same as those of the transition part. The upper surface of the material sampling part is a horizontal surface.
In this embodiment, the bottom of the cup portion is fixedly connected with the upper surface of the free end of the material drawing portion, so that the cup portion protrudes from the upper surface of the material drawing portion, and the central axis of the cup portion is perpendicular to the length extending direction of the material drawing portion.
The cup-shaped part of the embodiment is a cup body with an opening at the top and a conical cylinder shape, the diameter of the opening at the top of the cup body is 1.5mm-2.5mm, and the depth is 0.4mm-1.2mm. Preferably, the top opening of the cup in this embodiment has a diameter of 2.0mm and a depth of 0.6mm. The top edge of the cup body is sharp, so that nasal mucosa epithelial cells can be scraped by the top edge, and the epithelial cells fall into the cup body, so that the subsequent transfer and treatment are facilitated. The inner wall of the cup body is a slope surface which gradually narrows from the top of the cup to the bottom of the cup.
The holding part and the sampling part are connected in an inclined manner through the transition part, so that the holding part, the transition part and the sampling part are arranged in a stepped manner, the holding part and the cup-shaped part on the sampling part are convenient to hold and directly look at, and the sampling is safe and convenient. In addition, the transition part is positioned in the middle of the instrument, and the two ends are respectively connected with the material drawing part and the holding part, so that the function of limiting the material drawing part to enter the rear part of the nasal cavity can be achieved.
Example III
As shown in fig. 10, the structure of the nasal mucosa epithelial cell curet in this embodiment is basically the same as that in the second embodiment, except that the upper surface of the material taking part in this embodiment is a concave arc surface (as shown in fig. 11).
Other structures of this embodiment are substantially the same as those of the second embodiment, and will not be repeated here.
Although the present utility model has been described in detail hereinabove, the present utility model is not limited thereto, and modifications may be made by those skilled in the art in light of the principles of the present utility model, and it is therefore intended that all such modifications as fall within the scope of the present utility model.

Claims (10)

1. A nasal mucosal epithelial curet, comprising:
a holding part for facilitating the holding of an operator;
a material drawing part connected with the front end of the holding part;
the cup-shaped part is arranged at the free end of the material drawing part and used for scraping and holding nasal mucosa epithelial cells, and the top of the cup-shaped part protrudes from the material drawing part.
2. The nasal mucosal epithelial cell curet according to claim 1, wherein the cup is a cup having a shape of a straight cylinder or a tapered cylinder with a sharp top edge.
3. The nasal mucosa epithelial cell curet according to claim 1 or 2, wherein the bottom of the cup-shaped portion is fixedly connected with the upper surface of the free end of the sampling portion, and the central axis of the cup-shaped portion is perpendicular to the length extension direction of the sampling portion.
4. The nasal mucosal epithelial cell curet of claim 3, wherein said sampling portion is a flattened stem.
5. The nasal mucosal epithelial cell curet of claim 4, wherein said flattened stem tapers in width.
6. The nasal mucosal epithelial cell curet of claim 1, wherein said grip is an elongated flat bar.
7. The nasal mucosa epithelial cell curet according to claim 1, further comprising a transition portion between the grip portion and the sampling portion and having both ends obliquely connected to the grip portion and the sampling portion, respectively.
8. The nasal mucosa epithelial cell curet according to claim 7, wherein the transition portion and the grip portion have an included angle of 150 degrees to 160 degrees, and the transition portion and the sampling portion have an included angle of 145 degrees to 155 degrees.
9. The nasal mucosa epithelial cell curet according to claim 1, wherein the upper surface of the material-taking portion is a horizontal surface or a concave arc surface.
10. The nasal mucosal epithelial cell curet according to claim 2, wherein the diameter of the top opening of the cup is 1.5mm-2.5mm and the depth is 0.4mm-1.2mm.
CN202320415748.2U 2023-03-08 2023-03-08 Nasal mucosa epithelial cell curet Active CN219557387U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202320415748.2U CN219557387U (en) 2023-03-08 2023-03-08 Nasal mucosa epithelial cell curet

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202320415748.2U CN219557387U (en) 2023-03-08 2023-03-08 Nasal mucosa epithelial cell curet

Publications (1)

Publication Number Publication Date
CN219557387U true CN219557387U (en) 2023-08-22

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Family Applications (1)

Application Number Title Priority Date Filing Date
CN202320415748.2U Active CN219557387U (en) 2023-03-08 2023-03-08 Nasal mucosa epithelial cell curet

Country Status (1)

Country Link
CN (1) CN219557387U (en)

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