CN219109821U - Automatic animal stomach-filling drug delivery device for cordycepin experiment - Google Patents

Automatic animal stomach-filling drug delivery device for cordycepin experiment Download PDF

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Publication number
CN219109821U
CN219109821U CN202221711385.9U CN202221711385U CN219109821U CN 219109821 U CN219109821 U CN 219109821U CN 202221711385 U CN202221711385 U CN 202221711385U CN 219109821 U CN219109821 U CN 219109821U
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cordycepin
control box
stomach
fixed
rack
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CN202221711385.9U
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姚丽华
闫百仪
李雯茜
龚妍春
丁恺志
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Jiangxi Science and Technology Normal University
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Jiangxi Science and Technology Normal University
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Abstract

The utility model discloses an animal automatic stomach-filling drug delivery device for cordycepin experiments, which comprises a control box, wherein the control box is of a box body structure, a mounting frame is integrally formed on the left side of the control box, a sliding groove is integrally formed on the front side of the vertical part of the mounting frame, a rack is connected in a sliding manner in the sliding groove, a stepping motor is mounted on the mounting frame, a gear is fixed on an output shaft of the stepping motor, and the gear is in transmission fit with the rack. According to the utility model, by arranging the stepping motor, the gear rack mechanism and the related control circuit, the device is controlled by the stepping motor during drug administration, so that the influence of various subjective factors during manual operation can be avoided, and the accuracy of the drug administration amount can be ensured.

Description

Automatic animal stomach-filling drug delivery device for cordycepin experiment
Technical Field
The utility model relates to the technical field of animal stomach-filling administration devices, in particular to an animal automatic stomach-filling administration device for cordycepin experiments.
Background
The cordycepin is a natural new nuclear glycoside extracted from Cordyceps sinensis, has the activities of inhibiting tumor, resisting plasmodium, resisting fungi, resisting HIV-I type virus and selectively inhibiting clostridium, and attracts great importance in the pharmaceutical industry. In the research of the pharmacological properties or the mechanism of action of cordycepin, the experiment is usually carried out through animal experiments, and the cordycepin solution needs to be infused into the stomach of animals participating in the experiment.
In the process of gastric lavage, the dosage required by animals of different species and animals of the same species with different weights is different, and in order to ensure the accuracy of experimental results, the dosage in the process of gastric lavage needs to be accurately grasped; at present, when an animal stomach-filling experiment is carried out, a syringe is usually used for carrying out stomach-filling, an experimenter pushes a piston of the syringe by hand to enable liquid medicine to be filled into the stomach of an animal through a stomach-filling needle in the syringe, scales on the syringe are observed at the same time, when the piston is pushed to the corresponding scales, the required medicine dosage is indicated, but the injection quantity of the medicine is controlled in a manual operation and visual observation mode, the medicine dosage is deviated due to the fact that the force is not well mastered when the piston is pushed or the angle deviation is caused by the human factors such as the scale observation, and then the experimental result is inaccurate; thus, there is a need for an animal gastric lavage device that can automatically control the amount administered.
Disclosure of Invention
The utility model aims to solve the defects in the prior art, and provides an automatic animal stomach-lavage drug delivery device for a cordycepin experiment.
In order to achieve the above purpose, the present utility model adopts the following technical scheme:
the utility model provides an automatic stomach feeding device of irritating of animal for cordycepin experiment, includes the control box, the control box is the box structure, the left side integrated into one piece of control box has the mounting bracket, the front side integrated into one piece of the vertical part of mounting bracket has the spout, sliding connection has the rack in the spout, install step motor on the mounting bracket, be fixed with the gear on step motor's the output shaft, gear and rack form transmission cooperation.
As still further aspects of the utility model: the tail of the stepping motor is fixedly provided with a closed-loop driver, and the closed-loop driver is electrically connected with the stepping motor.
As still further aspects of the utility model: the front side of the vertical part of the mounting frame is integrally formed with a positioning block, and an injector is arranged in the positioning block.
As still further aspects of the utility model: and a fixing clamp is further fixed on the mounting frame and is fixed above the positioning block.
As still further aspects of the utility model: the liquid outlet end of the injector is communicated with an extension tube, and the end part of the extension tube is communicated with a stomach irrigation needle.
As still further aspects of the utility model: the left side of the middle part of spout is fixed with limit switch, the top left side integrated into one piece of rack has the clamp plate.
As still further aspects of the utility model: the control box is provided with a touch screen and a power switch, and a screen driving circuit is fixed on the back of the touch screen.
As still further aspects of the utility model: the control box is internally fixed with a main control board, and the power switch, the closed-loop driver, the limit switch and the screen driving circuit are all electrically connected to the main control board.
The beneficial effects of the utility model are as follows:
1. according to the utility model, by arranging the stepping motor, the gear rack mechanism and the related control circuit, the device is controlled by the stepping motor during drug administration, so that the influence of various subjective factors during manual operation can be avoided, and the accuracy of the drug administration amount can be ensured.
2. According to the utility model, the positioning block and the fixing clamp are arranged, so that the syringe for lavage can be conveniently taken and placed, and the liquid medicine is conveniently extracted.
3. The utility model can facilitate the human-computer interaction of the experimenters by arranging the touch screen and the related control circuit, and has simple operation.
Drawings
FIG. 1 is a schematic diagram showing the overall structure of an automatic animal gastric lavage drug delivery device for cordycepin experiments;
FIG. 2 is a schematic diagram showing the structure of the left front side of an automatic animal gastric lavage drug delivery device for cordycepin experiments;
FIG. 3 is an enlarged view of FIG. 2 at A;
fig. 4 is a schematic diagram of the internal structure of a control box of an automatic animal gastric lavage drug administration device for cordycepin experiments.
In the figure: the device comprises a 1-control box, a 2-touch screen, a 3-power switch, a 4-closed loop driver, a 5-stepping motor, a 6-mounting plate, a 7-syringe, an 8-extension tube, a 9-stomach-filling needle, a 10-mounting frame, an 11-fixing clamp, a 12-positioning block, a 13-sliding groove, a 14-rack, a 15-gear, a 16-limit switch, a 17-pressing plate, an 18-screen driving circuit and a 19-main control board.
Detailed Description
The technical scheme of the patent is further described in detail below with reference to the specific embodiments.
Embodiments of the present patent are described in detail below, examples of which are illustrated in the accompanying drawings, wherein the same or similar reference numerals refer to the same or similar elements or elements having the same or similar functions throughout. The embodiments described below by referring to the drawings are exemplary only for explaining the present patent and are not to be construed as limiting the present patent.
In the description of this patent, it should be understood that the terms "center," "upper," "lower," "front," "rear," "left," "right," "vertical," "horizontal," "top," "bottom," "inner," "outer," and the like indicate orientations or positional relationships based on the orientation or positional relationships shown in the drawings, merely to facilitate describing the patent and simplify the description, and do not indicate or imply that the devices or elements being referred to must have a particular orientation, be configured and operated in a particular orientation, and are therefore not to be construed as limiting the patent.
In the description of this patent, it should be noted that, unless explicitly stated and limited otherwise, the terms "mounted," "connected," and "disposed" are to be construed broadly, and may be fixedly connected, disposed, detachably connected, disposed, or integrally connected, disposed, for example. The specific meaning of the terms in this patent will be understood by those of ordinary skill in the art as the case may be.
An animal automatic stomach-filling drug delivery device for cordycepin experiments is shown in figures 1-4, and comprises a control box 1, wherein the control box 1 is of a box body structure, and a mounting frame 10 is integrally formed on the left side of the control box 1;
in order to be able to achieve a quantitative advance; the front side integrated into one piece of the vertical portion of mounting bracket 10 has spout 13, sliding connection has rack 14 in the spout 13, the right side integrated into one piece of the vertical portion of mounting bracket 10 has mounting panel 6, be fixed with step motor 5 on the mounting panel 6, be fixed with gear 15 on step motor 5's the output shaft, gear 15 forms transmission cooperation with rack 14.
To ensure the operation accuracy of the stepper motor 5; the tail of the stepping motor 5 is fixedly provided with a closed-loop driver 4, and the closed-loop driver 4 is electrically connected with the stepping motor 5.
The mounting frame 10 is also fixedly provided with a syringe 7, a positioning block 12 is integrally formed on the front side of the vertical part of the mounting frame 10 for determining the bottom end position of the syringe 7, a mounting groove is integrally formed in the middle of the positioning block 12, and the bottom end of the outer cylinder of the syringe 7 is inserted and fixed in the mounting groove of the positioning block 12.
In order to prevent the syringe 7 from coming out of the positioning block 12; the mounting frame 10 is also fixedly provided with a fixing clamp 11, the fixing clamp 11 is fixed above the positioning block 12, the fixing clamp 11 is made of elastic materials, and the outer cylinder of the injector 7 is elastically connected in the fixing clamp 11.
By arranging the stepping motor 5, the gear 15 and the rack 14, the forward pushing amount of the piston rod of the injector can be accurately controlled by the stepping motor 5 every time, so that the dosage during stomach irrigation can be accurately controlled.
In order to enable control of the stepper motor 5 and setting of relevant parameters; the control box 1 is provided with a touch screen 2 and a power switch 3, a screen driving circuit 18 is fixed on the back surface of the touch screen 2, the touch screen 2 is electrically connected with the screen driving circuit 18, and the screen driving circuit 18 is fixed on the inner wall of the front side of the control box 1; the control box 1 is internally fixed with a main control board 19, and the power switch 3, the closed-loop driver 4 and the screen driving circuit 18 are electrically connected to the main control board 19.
In order to allow the stepper motor 5 to stop running when the rack 14 is running to the lower limit position; the left side in the middle of spout 13 is fixed with limit switch 16, limit switch 16 electric connection is in main control board 19, the top left side integrated into one piece of rack 14 has clamp plate 17.
By arranging the pressing plate 17 and the limit switch 16, when the pressing plate 17 presses down the limit switch 16 in the running process of the rack 14, the main control board 19 can control the stepping motor 5 to stop running and mark the current position as a coordinate origin as a reference point of subsequent movement.
In order to facilitate the perfusion of the cordycepin liquid medicine into the stomach of the animal participating in the experiment; the liquid outlet end of the injector 7 is communicated with an extension tube 8, the end part of the extension tube 8 is communicated with a stomach-filling needle 9, and the stomach-filling needle 9 is a hollow catheter with a smooth end part.
The structural size in this embodiment is not particularly limited, and scaling can be properly performed according to the body sizes of the animals participating in the experiment, so that the device is suitable for quantitative gastric lavage administration experiments of animals of different body types.
Working principle: when the device is used, the power supply is firstly turned on, then the power switch 3 is pressed down to enable the device to start working, after the touch screen 2 displays a starting page and enters a homepage, the user clicks zero return, and the stepping motor 5 drives the rack 14 to slide downwards until the limit switch 16 acts.
After the zero return is finished, the prepared cordycepin solution is extracted by the injector 7, the bottom end of the outer cylinder of the injector is inserted into the central groove of the positioning block 12, the fixing clamp 11 is clamped on the outer wall of the injector 7, and the extension tube 8 and the stomach filling needle 9 are communicated with the solution outlet of the injector 7.
After the extension tube 8 is connected, clicking the exhaust on the touch screen 2, and clicking the exhaust continuously until the gas in the extension tube 8 is exhausted after clicking the rack 14 for 1mm upwards after clicking once, so that the cordycepin solution fills the whole extension tube 8;
then the stomach-filling needle 9 is inserted into the esophagus of the experimental animal, the 'drug administration' on the touch screen 2 is clicked, the required drug administration amount is input in the popped drug administration amount setting window, the 'determination' is clicked, the main control board 19 automatically calculates the required advancing distance of the rack 14 and the required rotating angle of the stepping motor 5 according to the input values, the stepping motor 5 is driven to rotate through the closed-loop driver 4, and the stepping motor stops running after the set drug administration amount is reached, and the 'completion' is prompted on the touch screen.
The foregoing is only a preferred embodiment of the present utility model, but the scope of the present utility model is not limited thereto, and any person skilled in the art, who is within the scope of the present utility model, should make equivalent substitutions or modifications according to the technical scheme of the present utility model and the inventive concept thereof, and should be covered by the scope of the present utility model.

Claims (4)

1. The utility model provides an animal automatic stomach-filling dosing device for cordycepin experiment, includes control box (1), its characterized in that, control box (1) is box structure, the left side integrated into one piece of control box (1) has mounting bracket (10), the front side integrated into one piece of the vertical part of mounting bracket (10) has spout (13), sliding connection has rack (14) in spout (13), install step motor (5) on mounting bracket (10), be fixed with gear (15) on the output shaft of step motor (5), gear (15) and rack (14) form transmission cooperation; a closed-loop driver (4) is fixed at the tail part of the stepping motor (5), and the closed-loop driver (4) is electrically connected with the stepping motor (5); a positioning block (12) is integrally formed on the front side of the vertical part of the mounting frame (10), and an injector (7) is arranged in the positioning block (12); a fixing clamp (11) is further fixed on the mounting frame (10), and the fixing clamp (11) is fixed above the positioning block (12); the liquid outlet end of the injector (7) is communicated with an extension tube (8), and the end part of the extension tube (8) is communicated with a stomach irrigation needle (9).
2. An automatic animal stomach-filling drug delivery device for cordycepin experiments according to claim 1, wherein a limit switch (16) is fixed on the left side of the middle of the chute (13), and a pressing plate (17) is integrally formed on the left side of the top end of the rack (14).
3. An automatic animal stomach-filling administration device for cordycepin experiments according to claim 2, wherein a touch screen (2) and a power switch (3) are installed on the control box (1), and a screen driving circuit (18) is fixed on the back of the touch screen (2).
4. An animal automatic stomach-filling administration device for cordycepin experiments according to claim 3, wherein the control box (1) is internally fixed with a main control board (19), and the power switch (3), the closed-loop driver (4), the limit switch (16) and the screen driving circuit (18) are electrically connected to the main control board (19).
CN202221711385.9U 2022-07-05 2022-07-05 Automatic animal stomach-filling drug delivery device for cordycepin experiment Active CN219109821U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202221711385.9U CN219109821U (en) 2022-07-05 2022-07-05 Automatic animal stomach-filling drug delivery device for cordycepin experiment

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202221711385.9U CN219109821U (en) 2022-07-05 2022-07-05 Automatic animal stomach-filling drug delivery device for cordycepin experiment

Publications (1)

Publication Number Publication Date
CN219109821U true CN219109821U (en) 2023-06-02

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ID=86521824

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202221711385.9U Active CN219109821U (en) 2022-07-05 2022-07-05 Automatic animal stomach-filling drug delivery device for cordycepin experiment

Country Status (1)

Country Link
CN (1) CN219109821U (en)

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