CN219058966U - Mesenchymal stem cell extraction element - Google Patents
Mesenchymal stem cell extraction element Download PDFInfo
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- CN219058966U CN219058966U CN202223429007.4U CN202223429007U CN219058966U CN 219058966 U CN219058966 U CN 219058966U CN 202223429007 U CN202223429007 U CN 202223429007U CN 219058966 U CN219058966 U CN 219058966U
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Abstract
The utility model relates to the technical field of stem cell extraction tools, in particular to a mesenchymal stem cell extraction device, which comprises a sampling test tube, wherein the sampling test tube consists of a transparent tube body and a sealing cover sleeved on the tube body at the top of the transparent tube body, a rubber plug is fixedly arranged at the central position of the sealing cover, a liquid medicine salt water bag is fixedly arranged on the bottom surface of the rubber plug, liquid medicine salt water for diluting blood is stored between the liquid medicine salt water bag and the rubber plug, a high-speed centrifugal device is arranged on the sampling test tube, the high-speed centrifugal device comprises a driving motor, a supporting disc is fixedly arranged at the tail end of an output shaft of the driving motor, a plurality of supporting connecting rods which are annularly and equidistantly arranged are fixedly arranged on the annular side surface of the supporting disc, a transparent cylinder is fixedly arranged at the tail end of the supporting connecting rods, and the transparent tube body is in plug-in fit with the transparent cylinder. The utility model can not pollute the device, is one person and one, can not produce cross infection, and is convenient to use.
Description
Technical Field
The utility model relates to the technical field of stem cell extraction tools, in particular to a mesenchymal stem cell extraction device.
Background
Mesenchymal stem cells belong to multipotent stem cells, have the characteristics of multidirectional differentiation potential, hematopoietic support, stem cell implantation promotion, immune regulation and self replication and the like, and when the mesenchymal stem cells are extracted, a corresponding stem cell extraction device is usually used;
the utility model patent with the authorized bulletin number of CN208857270U discloses a stem cell extraction device, which comprises a fixed frame, wherein a washing tank is arranged in the middle of the outer wall of the top of the fixed frame, a saline inlet pipe is arranged on the outer wall of one side of the top of the washing tank, a blood inlet pipe is arranged on the outer wall of one side of the top of the washing tank, a fixed seat is arranged on the inner wall of one side of the bottom of the fixed frame, a separation tank is arranged on the outer wall of the top of the fixed seat, a plasma outlet pipe, a stem cell outlet pipe and a red blood cell outlet pipe are arranged on the outer wall of the bottom of the separation tank, a second one-way valve is arranged in the plasma outlet pipe, and a third one-way valve is arranged in the stem cell outlet pipe;
although the technical scheme has the advantages that blood is washed by normal saline, coagulation particles are removed, the viscosity of plasma is reduced, the blood is centrifugally separated by utilizing an ultracentrifuge, cell clusters, coagulation particles and pollutants mixed in stem cells are filtered, the separation speed is increased, the stem cells are prevented from being polluted, and the activity of the stem cells is kept. In view of this, we propose a mesenchymal stem cell extraction device.
Disclosure of Invention
The present utility model is directed to a mesenchymal stem cell extraction device, which solves the above-mentioned drawbacks of the prior art.
In order to achieve the above purpose, the present utility model provides the following technical solutions:
the mesenchymal stem cell extraction device comprises a sampling test tube, wherein the sampling test tube consists of a transparent tube body and a sealing cover sleeved on the tube body at the top of the transparent tube body, a rubber plug is fixedly arranged at the center of the sealing cover, a liquid medicine saline bag is fixedly arranged on the bottom surface of the rubber plug, and liquid medicine saline for diluting blood is stored between the liquid medicine saline bag and the rubber plug;
the sampling test tube is provided with a high-speed centrifugal device, the high-speed centrifugal device comprises a driving motor, a supporting disc is fixedly arranged at the tail end of an output shaft of the driving motor, a plurality of supporting connecting rods which are annularly arranged at equal intervals are fixedly arranged on the annular side face of the supporting disc, a transparent tube is fixedly arranged at the tail end of each supporting connecting rod, and the transparent tube body is in plug-in fit with the transparent tube.
Preferably, the transparent tube body is made of transparent materials and is used for facilitating observation.
Preferably, the transparent tube body is adapted to the size of the transparent tube for preventing relative shaking.
Preferably, the rubber plug is in plug connection with the transparent tube body, and the liquid medicine brine bag is positioned in the transparent tube body, so that after the liquid medicine brine bag is punctured, the liquid medicine brine in the liquid medicine brine bag can enter the transparent tube body, and the dilution operation of blood in the transparent tube body is realized.
Preferably, the top surface of the transparent tube is hinged with a top cover sleeved on the sealing cover through a hinge, and the top cover is used for limiting the transparent tube body and the sealing cover.
Preferably, the annular side of top cap is articulated through the hinge and has the rectangular plate, the terminal fixed mounting of rectangular plate has the elastic plate, fixed mounting has the limiting plate on the support connecting rod, the elastic plate card is in on the top plate body bottom surface of limiting plate, be convenient for carry out spacingly to the top cap, realize compressing tightly the operation to transparent body and sealed lid.
Preferably, a blocking clamping block is fixedly arranged on the bottom surface of the top plate body of the limiting plate and used for blocking the elastic plate from slipping from the end part of the top plate body of the limiting plate.
Compared with the prior art, the utility model has the beneficial effects that:
1. according to the utility model, blood can be directly input into the sampling test tube through the sampling test tube, after the liquid medicine salt water bag is punctured, the liquid medicine salt water in the liquid medicine salt water bag can enter the transparent tube body to realize the dilution operation on the blood, and then the sampling test tube is placed on the high-speed centrifugal device to carry out the centrifugal operation, so that mesenchymal stem cells can be extracted after centrifugal layering.
2. According to the utility model, through the elastic plate, the limiting plate and the blocking clamping block, the elastic plate is conveniently abutted against the bottom surface of the top plate body of the limiting plate, the top cover is limited, and the transparent pipe body and the sealing cover which are inserted into the transparent cylinder are further limited, so that the transparent pipe body cannot slip from the transparent cylinder in the centrifuging process.
Drawings
FIG. 1 is a schematic diagram of the overall structure of the present utility model;
FIG. 2 is a schematic diagram of an explosive structure according to the present utility model;
FIG. 3 is a schematic view of an exploded view of a sample tube according to the present utility model;
FIG. 4 is a schematic view of a portion of the structure of the present utility model;
fig. 5 is an enlarged view of the utility model at a in fig. 2.
The meaning of each reference numeral in the figures is:
1. sampling test tubes; 10. a transparent tube body; 11. sealing cover; 12. a rubber stopper; 13. a liquid medicine brine bag;
2. a high-speed centrifugal device; 20. a driving motor; 21. a support plate; 22. a support link; 23. a transparent tube; 24. a top cover; 25. a rectangular plate; 251. an elastic plate; 26. a limiting plate; 261. blocking the clamping block.
Detailed Description
The following description of the embodiments of the present utility model will be made clearly and completely with reference to the accompanying drawings, in which it is apparent that the embodiments described are only some embodiments of the present utility model, but not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the utility model without making any inventive effort, are intended to be within the scope of the utility model.
Referring to fig. 1-5, the present utility model provides a technical solution: the mesenchymal stem cell extraction device comprises a sampling test tube 1, wherein the sampling test tube 1 consists of a transparent tube body 10 and a sealing cover 11 sleeved on the tube body at the top of the transparent tube body 10, and the transparent tube body 10 is made of transparent materials and is used for facilitating observation; the central point of sealed lid 11 puts fixed mounting has rubber buffer 12, fixed mounting has liquid medicine salt water bag 13 on the bottom surface of rubber buffer 12, liquid medicine salt water bag 13 and the rubber buffer 12 between store the liquid medicine salt water bag that is used for diluting blood, rubber buffer 12 is the rubber material, when using, along with external blood drawing needle passes rubber buffer 12 and with liquid medicine salt water bag 13 puncture back, liquid medicine in the liquid medicine salt water bag 13 can enter into transparent body 10, at this moment, along with blood along the blood drawing needle entering, can enter into transparent body 10, realize utilizing transparent body 10 to carry out the storage operation to blood, liquid medicine salt water bag 13 that enters into transparent body 10 in addition can dilute the operation to blood, reduce the viscosity, facilitate the use.
Specifically, be provided with high-speed centrifugal device 2 on the sample test tube 1, high-speed centrifugal device 2 includes driving motor 20, driving motor 20's output shaft end fixed mounting has supporting disk 21, fixed mounting has a plurality of support connecting rods 22 that are cyclic annular equidistant range on the annular side of supporting disk 21, supporting connecting rod 22's end fixed mounting has transparent section of thick bamboo 23, peg graft the cooperation between transparent body 10 and the transparent section of thick bamboo 23, be convenient for utilize driving motor 20 work, drive supporting disk 21, supporting connecting rod 22, transparent section of thick bamboo 23 and transparent body 10 rotate, carry out the centrifugation operation.
In this embodiment, the transparent tube 10 is adapted to the transparent tube 23 in size to prevent relative shaking.
Specifically, the rubber plug 12 is in plug connection with the transparent tube body 10, and the liquid medicine brine bag 13 is positioned in the transparent tube body 10, so that after the liquid medicine brine bag 13 is punctured, the liquid medicine brine in the liquid medicine brine bag 13 can enter the transparent tube body 10, and the dilution operation of blood in the transparent tube body 10 is realized.
Further, a top cover 24 sleeved on the sealing cover 11 is hinged on the top surface of the transparent tube 23 through a hinge, and the top cover 24 is used for limiting the transparent tube body 10 and the sealing cover 11.
In addition, the annular side of the top cover 24 is hinged with a rectangular plate 25 through a hinge, the rectangular plate 25 can rotate along the horizontal direction, the tail end of the rectangular plate 25 is fixedly provided with an elastic plate 251, the support connecting rod 22 is fixedly provided with a limiting plate 26, the elastic plate 251 is abutted against the bottom surface of the top plate body of the limiting plate 26, the top cover 24 is conveniently limited, and the transparent pipe body 10 and the sealing cover 11 are pressed.
It should be noted that, the blocking clamping block 261 is fixedly installed on the bottom surface of the top plate body of the limiting plate 26, and the blocking clamping block 261 is used for blocking the elastic plate 251 from sliding off from the end of the top plate body of the limiting plate 26, so as to realize the anti-sliding and limiting operation of the elastic plate 251.
It should be noted that the driving motor 20 in the present embodiment is a conventional technology, and will not be described herein.
When the mesenchymal stem cell extraction device is used, a blood taking needle with needles at two ends is used for taking blood, one needle is inserted into a blood vessel, the other needle passes through a rubber plug 12 and a liquid medicine saline bag 13 is punctured, as the inside of the transparent tube body 10 is in a negative pressure state in advance, under the negative pressure condition, blood in the blood vessel can enter the transparent tube body 10, and meanwhile, after the needle punctures the liquid medicine saline bag 13, the liquid medicine saline water in the liquid medicine saline bag 13 can enter the transparent tube body 10, and the blood in the transparent tube body 10 is diluted;
after blood collection is completed, the needle on the rubber plug 12 is pulled out, the transparent tube body 10 is inserted into the transparent tube 23, the top cover 24 is closed, the elastic plate 251 is clamped on the bottom surface of the top plate body of the limiting plate 26, the driving motor 20 is connected with an external power supply and is enabled to work, the driving motor 20 works, an output shaft on the driving motor rotates to drive the supporting disc 21, the supporting connecting rod 22, the transparent tube 23 and the transparent tube body 10 to rotate, centrifugal operation is carried out, blood is divided into a plasma layer, a stem cell layer and a red blood cell layer after centrifugal operation, and then mesenchymal stem cells of the stem cell layer are sucked out by using an external syringe to complete extraction operation, so that the device is convenient to use.
The foregoing has shown and described the basic principles, principal features and advantages of the utility model. It will be understood by those skilled in the art that the present utility model is not limited to the above-described embodiments, and that the above-described embodiments and descriptions are only preferred embodiments of the present utility model, and are not intended to limit the utility model, and that various changes and modifications may be made therein without departing from the spirit and scope of the utility model as claimed. The scope of the utility model is defined by the appended claims and equivalents thereof.
Claims (7)
1. A mesenchymal stem cell extraction device, characterized in that: the blood sampling device comprises a sampling test tube (1), wherein the sampling test tube (1) consists of a transparent tube body (10) and a sealing cover (11) sleeved on the tube body at the top of the transparent tube body (10), a rubber plug (12) is fixedly arranged at the central position of the sealing cover (11), a liquid medicine saline bag (13) is fixedly arranged on the bottom surface of the rubber plug (12), and liquid medicine saline for diluting blood is stored between the liquid medicine saline bag (13) and the rubber plug (12);
be provided with high-speed centrifugal device (2) on sample test tube (1), high-speed centrifugal device (2) are including driving motor (20), driving motor's (20) output shaft end fixed mounting has supporting disk (21), fixed mounting has a plurality of support connecting rods (22) that are annular equidistant range on the annular side of supporting disk (21), the terminal fixed mounting of support connecting rod (22) has transparent section of thick bamboo (23), transparent body (10) with peg graft the cooperation between transparent section of thick bamboo (23).
2. The mesenchymal stem cell extraction apparatus of claim 1, wherein: the transparent pipe body (10) is made of transparent materials and is used for facilitating observation.
3. The mesenchymal stem cell extraction apparatus of claim 1, wherein: the transparent tube body (10) is adapted to the dimensions of the transparent tube (23) for preventing relative shaking.
4. The mesenchymal stem cell extraction apparatus of claim 1, wherein: the rubber plug (12) is in plug-in fit with the transparent pipe body (10), and the liquid medicine brine bag (13) is positioned in the transparent pipe body (10).
5. The mesenchymal stem cell extraction apparatus of claim 1, wherein: a top cover (24) sleeved on the sealing cover (11) is hinged to the top surface of the transparent cylinder (23) through a hinge, and the top cover (24) is used for limiting the transparent pipe body (10) and the sealing cover (11).
6. The mesenchymal stem cell extraction apparatus of claim 5, wherein: the annular side of the top cover (24) is hinged with a rectangular plate (25) through a hinge, the tail end of the rectangular plate (25) is fixedly provided with an elastic plate (251), the support connecting rod (22) is fixedly provided with a limiting plate (26), and the elastic plate (251) is clamped on the bottom surface of the top plate body of the limiting plate (26).
7. The mesenchymal stem cell extraction apparatus of claim 6, wherein: the top plate body bottom surface of limiting plate (26) is last fixed mounting to block fixture block (261), block fixture block (261) and be used for stopping elastic plate (251) from the top plate body tip slippage of limiting plate (26).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202223429007.4U CN219058966U (en) | 2022-12-21 | 2022-12-21 | Mesenchymal stem cell extraction element |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202223429007.4U CN219058966U (en) | 2022-12-21 | 2022-12-21 | Mesenchymal stem cell extraction element |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN219058966U true CN219058966U (en) | 2023-05-23 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202223429007.4U Active CN219058966U (en) | 2022-12-21 | 2022-12-21 | Mesenchymal stem cell extraction element |
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| CN (1) | CN219058966U (en) |
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2022
- 2022-12-21 CN CN202223429007.4U patent/CN219058966U/en active Active
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