CN218726635U - Processing apparatus based on terahertz time-domain spectroscopy system detects expired gas - Google Patents

Abstract

The application provides a processing apparatus based on terahertz time-domain spectroscopy system detects expired gas, including gaseous enrichment device, desorption device and terahertz time-domain spectroscopy detection air chamber. The gas enrichment device comprises an enrichment pipe which is used for collecting the exhaled gas of the human body and adsorbing and concentrating the exhaled gas, so that the sample is higher than the detection limit of the terahertz time-domain spectroscopy system. The desorption device comprises a gas storage bottle, a heating device and a gas guide pipe, the enrichment pipe can be installed on the heating device and heated, one end of the enrichment pipe is communicated with the gas storage bottle, and the other end of the enrichment pipe is connected with the terahertz time-domain spectroscopy detection gas chamber through the gas guide pipe. A sensor adopting a high-resistance silicon wafer substrate is arranged in the terahertz time-domain spectrum detection air chamber to replace a traditional terahertz chip, so that the cost is reduced, and meanwhile, a wider spectrum sample signal is obtained for subsequent data analysis. The processing device has the advantages of being simple to operate, intuitive in data, adjustable in gas flow rate and the like.

Description

Processing apparatus based on terahertz time-domain spectroscopy system detects expired gas

Technical Field

The application belongs to the technical field of gas enrichment and terahertz time-domain spectroscopy detection, and particularly relates to a processing device for detecting exhaled gas based on a terahertz time-domain spectroscopy system.

Background

Terahertz is a new radiation source with many unique advantages and is widely applied to the field of cross frontier. Terahertz spectra (including transmission spectra and reflection spectra) of substances contain very abundant physical and chemical information, and experiments using terahertz time-domain detection technology have great requirements on the components of gases. The humidity of the exhaled air of a human body is very high, and the content of VOCs (volatile organic compounds) in the exhaled air is often in the ppb (parts per billion) level or even lower, so that the exhaled air is not suitable for detecting gas components by adopting a terahertz time-domain spectroscopy detection technology, which increases the detection difficulty.

The existing oil-soluble gas enrichment device can concentrate and screen gas so as to be suitable for the terahertz time-domain spectroscopy detection technology. However, when oil-gas separation is carried out after gas concentration, some gas organic compounds are dissolved in oil, so that errors occur in the final result of terahertz time-domain spectroscopy detection.

SUMMERY OF THE UTILITY MODEL

An object of the embodiment of the application is to provide a processing apparatus based on terahertz time-domain spectroscopy system detects expired gas to realize detecting human expired gas composition through terahertz time-domain spectroscopy detecting system, solve the technical problem that the deviation appears in the result when concentrating the VOCs composition in the human expired gas through the oil-soluble gas enrichment device that exists among the prior art simultaneously.

In order to achieve the purpose, the technical scheme adopted by the application is as follows: the utility model provides a processing apparatus based on terahertz time-domain spectroscopy system detects expired gas, includes gas enrichment device, desorption device and terahertz time-domain spectroscopy detects the gas chamber. The gas enrichment device comprises an enrichment pipe, and the enrichment pipe is used for collecting the exhaled gas of the human body and adsorbing and concentrating the exhaled gas in the enrichment pipe. The desorption device comprises a gas storage bottle, a heating device and a gas guide pipe, wherein the heating device is used for installing the enrichment pipe and heating the enrichment pipe. After the enrichment pipe is installed on the heating device, one end of the enrichment pipe is communicated with the gas storage bottle, and the other end of the enrichment pipe is communicated with one end of the gas guide pipe. The other end of the gas guide tube is connected with a terahertz time-domain spectroscopy detection gas chamber, and a sensor adopting a high-resistance silicon wafer substrate is arranged in the terahertz time-domain spectroscopy detection gas chamber.

Optionally, the gas enrichment device comprises a blowing nozzle, a main gas pipe, a collection gas pipe, a valve and an air extractor, one end of the main gas pipe and one end of the collection gas pipe are both communicated with the blowing nozzle, one end of the enrichment pipe is communicated with the other end of the collection gas pipe through the valve, and the other end of the enrichment pipe is communicated with the air extractor through the valve.

Optionally, the gas enrichment device comprises a first flow meter connected between the enrichment tube and the gas extraction device.

Optionally, the gas enrichment device comprises a first control unit and a relay, and the valve is a solenoid valve and is connected with the first control unit through the relay.

Optionally, the gas enrichment device comprises a power supply and a voltage stabilizing and reducing module, the power supply is electrically connected with the voltage stabilizing and reducing module, and the first control unit is electrically connected with the voltage stabilizing and reducing module.

Optionally, the gas enrichment device comprises a driving module, and the first control unit controls the gas extraction device through the driving module.

Optionally, the enrichment pipe is one of a Tenax-TA filling pipe, a carbon molecular sieve filling pipe, a Tenax-TA and carbon molecular sieve mixed filling pipe.

Optionally, the desorption device comprises a second flow meter connected between the gas cylinder and the enrichment tube.

Optionally, the desorption device comprises a second control unit and an electromagnetic valve, the electromagnetic valve is arranged between the gas storage bottle and the enrichment pipe and between the enrichment pipe and the terahertz time-domain spectroscopy detection gas chamber, and the electromagnetic valve is electrically connected with the second control unit.

Optionally, the desorption device comprises a second control unit and a temperature controller connected between the second control unit and the heating device.

The application provides a processing apparatus based on terahertz time-domain spectroscopy system detects expired gas's beneficial effect lies in: compared with the prior art, the processing device for detecting the exhaled gas based on the terahertz time-domain spectroscopy system collects the exhaled gas of a human body through the enrichment pipe and adsorbs and concentrates the exhaled gas in the enrichment pipe, so that the collected exhaled gas sample is higher than the detection limit of the terahertz time-domain spectroscopy system, and the processing device is suitable for detecting the terahertz time-domain spectroscopy system. And then the enrichment pipe is taken down from the gas enrichment device and is arranged in a heating device for heating, so that the expired gas adsorbed in the enrichment pipe is desorbed. And then the desorbed gas can be blown into a terahertz time-domain spectroscopy detection gas chamber through the gas in the gas storage cylinder to detect the gas components. The VOCs in the exhaled air of the human body obtained by enrichment, concentration and desorption in the mode are accurate and have no deviation, and the accuracy of a subsequent detection result is ensured. A sensor adopting a high-resistance silicon wafer substrate is arranged in the terahertz time-domain spectrum detection gas chamber to replace a traditional terahertz chip, so that the cost is reduced, and meanwhile, a wider spectrum sample signal is obtained for subsequent data analysis. The processing apparatus for detecting exhaled gas based on the terahertz time-domain spectroscopy system has the advantages of simplicity in operation, visual data, adjustable gas flow rate and the like.

Drawings

In order to more clearly illustrate the technical solutions in the embodiments of the present application, the drawings needed to be used in the embodiments or the prior art descriptions will be briefly described below, and it is obvious that the drawings in the following description are only some embodiments of the present application, and it is obvious for those skilled in the art to obtain other drawings based on these drawings without inventive exercise.

Fig. 1 is a schematic structural diagram of a gas enrichment device of a processing device for detecting exhaled gas based on a terahertz time-domain spectroscopy system provided in an embodiment of the present application;

fig. 2 is a schematic structural diagram of a desorption device of a processing device for detecting exhaled air based on a terahertz time-domain spectroscopy system and a terahertz time-domain spectroscopy detection gas chamber which are connected together according to an embodiment of the present application;

fig. 3 is a circuit structure diagram of the structure shown in fig. 2.

Wherein, in the figures, the respective reference numerals:

1-a gas enrichment device; 11-enrichment tube; 12-a blowing nozzle; 13-main trachea; 14-collecting trachea; 15-a valve; 16-a suction device; 17-a first flow meter; 18-a first control unit; 19-a relay; 20-TTL-RS485 module; 21-a power supply; 22-a voltage stabilizing and reducing module; 23-a drive module; a 24-T interface member; 25-an operating panel; 3-a desorption device; 31-gas cylinder; 32-a heating device; 33-an airway tube; 34-a second flow meter; 35-a second control unit; 36-a solenoid valve; 37-a relay; 38-TTL-RS485 module; 39-temperature controller; 40-a rectifier; 41-power supply; 42-voltage stabilizing and reducing module; 43-an operating panel; 44-a steering engine; 45-a steering engine driving module; 46-a first heat sink; 47-a second heat sink; 5-terahertz time-domain spectroscopy detection gas chamber.

Detailed Description

In order to make the technical problems, technical solutions and advantageous effects to be solved by the present application clearer, the present application is further described in detail below with reference to the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are merely illustrative of and not restrictive on the broad application.

It will be understood that when an element is referred to as being "secured to" or "disposed on" another element, it can be directly on the other element or be indirectly on the other element. When an element is referred to as being "connected to" another element, it can be directly connected to the other element or be indirectly connected to the other element.

It will be understood that the terms "length," "width," "upper," "lower," "front," "rear," "left," "right," "vertical," "horizontal," "top," "bottom," "inner," "outer," and the like, as used herein, refer to an orientation or positional relationship indicated in the drawings that is solely for the purpose of facilitating the description and simplifying the description, and do not indicate or imply that the device or element being referred to must have a particular orientation, be constructed and operated in a particular orientation, and thus should not be considered as limiting the present application.

Furthermore, the terms "first", "second" and "first" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance or implicitly indicating the number of technical features indicated. Thus, a feature defined as "first" or "second" may explicitly or implicitly include one or more of that feature. In the description of the present application, "a plurality" means two or more unless specifically limited otherwise.

Referring to fig. 1, a processing apparatus for detecting exhaled breath based on a terahertz time-domain spectroscopy system provided in an embodiment of the present application will now be described. The processing device for detecting the exhaled gas based on the terahertz time-domain spectroscopy system comprises a gas enrichment device 1, a desorption device 3 and a terahertz time-domain spectroscopy detection gas chamber 5. The gas enrichment device 1 comprises an enrichment pipe 11, wherein the enrichment pipe 11 is used for collecting the exhaled gas of a human body and adsorbing and concentrating the exhaled gas in the enrichment pipe 11. The enrichment tube 11 has micro fused silica extraction fibers therein and is filled with an adsorbent, for example, tenax-TA adsorbent, which is 2,6-diphenyl furan porous polymer resin, can be used. The adsorbent in the enrichment tube 11 can extract trace organic compounds in exhaled air entering the enrichment tube 11 by adopting a Solid Phase Micro-Extraction (SPME) mode, so that the effect of concentrating and enriching volatile organic compounds in the exhaled air of a human body is achieved.

The desorption device 3 comprises a gas cylinder 31, a heating device 32 and a gas guide pipe 33. The gas cylinder 31 stores therein a gas such as nitrogen or helium. The heating device 32 is used to install the enrichment pipe 11 and heat the enrichment pipe 11, thereby desorbing the volatile organic compounds adsorbed in the enrichment pipe 11. When the device is used, the enrichment pipe 11 which is taken down from the gas enrichment device 1 and is used for collecting the exhaled gas to be detected is firstly arranged in the heating device 32. When the enriching pipe 11 is installed in the heating device 32, one end of the enriching pipe 11 is communicated with the gas bomb 31, and the other end of the enriching pipe 11 is communicated with one end of the gas guide pipe 33. The other end of the air duct 33 is connected with the terahertz time-domain spectroscopy detection air chamber 5. That is, the other end of the enrichment tube 11 is communicated with the terahertz time-domain spectroscopy detection gas chamber 5 through the gas guide tube 33. During operation, after the exhaled gas of the human body is collected through the enrichment pipe 11, the enrichment pipe 11 is taken down from the gas enrichment device 1 and is installed in the heating device 32, and the enrichment pipe 11 is heated through the heating device 32, so that organic compounds adsorbed in the gas of the enrichment pipe 11 are desorbed and desorbed under a high-temperature condition; after the volatile organic compound gas adsorbed in the enrichment pipe 11 is desorbed, opening the gas storage cylinder 31 to enable the gas in the gas storage cylinder 31 to enter the enrichment pipe 11 and be fused with the desorbed volatile organic compound; and along with the gas is continuously filled into the enrichment pipe 11 from the gas storage bottle 31, the desorbed volatile organic compounds can be swept into the terahertz time-domain spectroscopy detection gas chamber 5 through the gas guide pipe 33 by the gas in the gas storage bottle 31 for detection and analysis. And starting a terahertz light path in the terahertz time-domain spectroscopy detection gas chamber 5, so that the terahertz time-domain spectroscopy detection can be performed on the gas to be detected (namely the desorbed volatile organic compound).

Compared with the prior art, the processing apparatus based on terahertz time-domain spectroscopy system detection exhaled air that this application provided gathers and adsorbs concentrated human exhaled air through enrichment pipe 11 among the gas enrichment device 1, makes the sample be higher than terahertz time-domain spectroscopy system's detection limit to accord with terahertz time-domain spectroscopy system and detect the requirement to gas sample composition. The enrichment tube 11 is removed from the gas enrichment device 1 and installed in the heating device 32 to be heated, thereby desorbing the expired gas adsorbed in the enrichment tube 11. Then the desorbed gas can be purged into the terahertz time-domain spectroscopy detection gas chamber 5 through the gas in the gas storage cylinder 31 for gas component detection. The VOCs in the exhaled air of the human body obtained by enrichment, concentration and desorption in the mode are accurate and have no deviation, and the accuracy of a subsequent detection result is ensured. A sensor adopting a high-resistance silicon wafer substrate is arranged in the terahertz time-domain spectrum detection gas chamber 5 to replace a traditional terahertz chip, so that the cost is reduced, and meanwhile, a wider spectrum sample signal is obtained for subsequent data analysis. The processing apparatus for detecting exhaled gas based on the terahertz time-domain spectroscopy system has the advantages of simplicity in operation, visual data, adjustable gas flow rate and the like.

In another embodiment of the present application, the gas enrichment device 1 comprises a mouthpiece 12, a main gas pipe 13, a collection gas pipe 14, a valve 15, and a suction device 16. The mouthpiece 12 is adapted to be worn over the mouth of the person taking the sample to blow air to collect the exhaled air. One end of the main air pipe 13 and one end of the collecting air pipe 14 are both communicated with the mouthpiece 12, so that the gas exhaled by the sampler can enter the main air pipe 13 and also can enter the collecting air pipe 14. One end of the enrichment tube 11 is communicated with the other end of the collection air tube 14 through a valve 15, in other words, the valve 15 is connected between the collection air tube 14 and the enrichment tube 11. The other end of the enrichment pipe 11 is communicated with the air suction device 16 through a valve 15, in other words, the valve 15 is connected between the enrichment pipe 11 and the air suction device 16. Therefore, both ends of the enrichment pipe 11 are provided with valves 15.

Because the gas just beginning to be exhaled when people exhale the gas has more steam, and the exhaled gas at the tail part only contains more volatile organic compounds, when sampling is carried out through the gas enrichment device 1, the valve 15 is closed firstly, so that the collection trachea 14 is closed. A sampler blows air towards the blowing nozzle 12, the air exhaled by the sampler firstly enters the main air pipe 13 and cannot enter the collecting air pipe 14, and the moisture exhaled by the sampler is exhausted through the other end of the main air pipe 13, so that the moisture exhaled by the sampler can be exhausted; when the tail gas part needing to be collected is reached, the valve 15 is opened, the collecting gas pipe 14 is opened, the gas extraction device 16 is started to extract gas, at the moment, gas exhaled by a sampler can enter the collecting gas pipe 14, and the gas extraction device 16 absorbs volatile organic compounds at the tail part of the exhaled gas into the enrichment pipe 11. When the gas collected in the enrichment pipe 11 reaches a preset amount, the gas extraction device 16 stops gas extraction, the valve 15 is closed, the collection gas pipe 14 is closed, the collection and concentration of the gas are completed, and then the gas sample is desorbed and then can be suitable for terahertz time-domain spectroscopy detection and analysis. In another embodiment of the present application, the mouthpiece 12 is a disposable spirometric silicone mouthpiece. The air extractor 16 is an air pump, and for example, a micro vacuum pump of C13L-51J-0010 type, DC-5V, with an average flow rate of 300ml/min can be used.

In another embodiment of the present application, the gas enrichment device 1 comprises a first flow meter 17, the first flow meter 17 being connected between the enrichment tube 11 and the suction device 16. In this way, the first flow meter 17 can detect the gas flow passing through the collecting gas pipe 14, so that the amount of the gas collected in the enrichment pipe 11 can be calculated, and the gas can be collected quantitatively. Optionally, the first flow meter 17 is a mass flow meter model MFC1000-500 sccm-A.

In another embodiment of the present application, the gas enrichment device 1 comprises a first control unit 18 and a relay 19, the first control unit 18 being communicatively connected to the first flow meter 17 via a TTL-RS485 module 20. Thus, the gas flow value detected by the first flowmeter 17 in real time is transmitted to the first control unit 18 through the TTL-RS485 module 20. The valve 15 is a solenoid valve and is connected to a first control unit 18 via a relay 19. Optionally, valve 15 is a DC-24V two-position, normally closed solenoid valve.

When in use, the first control unit 18 can determine the gas flow collected in the enrichment pipe 11 according to the gas flow data fed back by the first flow meter 17 in real time. When the gas quantity collected in the enrichment pipe 11 reaches a set value, the first control unit 18 controls the closing valve 15 through the relay 19, the collection gas pipe 14 is closed, and the gas does not enter the enrichment pipe 11 any more.

Optionally, the first control Unit 18 is a Micro Controller Unit (MCU) with a model number of STM32F407ZET6, which is also called a single chip microcomputer, and outputs high and low levels through an IO port to control the solenoid valve.

In another embodiment of the present application, the gas enrichment apparatus 1 further comprises a power source 21 and a voltage stabilizing and dropping module 22, the power source 21 is electrically connected to the voltage stabilizing and dropping module 22, and the first control unit 18 is electrically connected to the voltage stabilizing and dropping module 22.

Optionally, the power supply 21 is a 24V lithium battery, and the power supply 21 is electrically connected to the relay 19 to supply power to the relay 19. The power supply 21 supplies power to the first control unit 18 after the voltage stabilizing and reducing action of the voltage stabilizing and reducing module 22.

In another embodiment of the present application, the gas enrichment device 1 comprises a driving module 23, the first control unit 18 is electrically connected to the driving module 23, and the driving module 23 is electrically connected to the pumping device 16. In this way, the first control unit 18 controls the suction device 16 through the drive module 23. When the first control unit 18 opens the valve 15 through the relay 19 for gas collection, the first control unit 18 correspondingly drives the air extractor 16 through the driving module 23 to start air extraction. Similarly, when the amount of the gas collected in the enrichment pipe 11 reaches a set value, the first control unit 18 closes the valve 15 through the relay 19 to stop collecting the gas, and accordingly the first control unit 18 controls the gas exhaust device 16 to stop working through the driving module 23. Optionally, the driving module 23 is an L298N motor driving chip.

In another embodiment of the present application, the enrichment pipe 11 is one of a Tenax-TA filling pipe, a carbon molecular sieve filling pipe, a Tenax-TA and carbon molecular sieve mixing filling pipe. For example, the enrichment pipe 11 is a Tenax-TA and carbon molecular sieve mixed filling pipe, and the Tenax-TA and the carbon molecular sieve in the enrichment pipe 11 are filled according to the mass ratio of 3:1. Or the enrichment pipe 11 is a Tenax-TA filling pipe, and a Tenax-TA material is used as an adsorbent.

In another embodiment of the present application, the gas enrichment device 1 further comprises a T-shaped interface 24, and one end of the main gas pipe 13 and one end of the collection gas pipe 14 are communicated with the mouthpiece 12 through the T-shaped interface 24. The T-shaped mouthpiece 24 is a three-way mouthpiece, and can connect the mouthpiece 12, the main air tube 13, and the collection air tube 14 to each other. The other end of the main gas tube 13 and the exhaust port of the suction device 16 are also connected together by a T-shaped interface 24.

In another embodiment of the present application, the connecting pipelines between the enrichment tube 11, the main gas tube 13, the collection gas tube 14 and the air extractor 16 are all peristaltic pump silicone tubes with an outer diameter of 6mm and an inner diameter of 4 mm. The peristaltic pump silicone tube is a flexible tube made of silica gel with different properties according to the difference of the dynamic property and the conveying material of the peristaltic pump, and has certain elasticity and wear resistance, good toughness and tear resistance, good air tightness, no leakage, low adsorptivity, good temperature resistance and difficult aging.

In another embodiment of the present application, the gas enrichment device 1 further comprises an operation panel 25, optionally, the operation panel 25 is a TFT-LCD display screen. The power source 21 and the first control unit 18 are electrically connected to the operation panel 25. The operation of the entire gas enrichment device 1 can be controlled by the user through the operation panel 25.

Taking the first control unit 18 as a single chip, the valve 15 as an electromagnetic valve, the air extractor 16 as an air pump, the driving module 23 as an L298N motor driving chip, and the operation panel 25 as a TFT-LCD display screen as an example, the operation process of the gas enrichment device 1 is as follows: after a user finishes parameter setting on a TFT-LCD display screen and clicks to start working, a sampler firstly aims at the blowing nozzle 12 to blow air, so that the moisture exhaled firstly is exhausted through the main air pipe 13, and at the moment, the electromagnetic valve and the collecting air pipe 14 are closed; then the singlechip outputs high level through the IO port to open the control relay 19 for conduction, then controls to open the electromagnetic valve of the acquisition air pipe 14, and simultaneously outputs a PWM signal to the L298N motor driving chip to enable the air pump to start working; the single chip microcomputer finishes data acquisition of the first flowmeter 17 according to a communication protocol of the flowmeter and user set parameters, and adjusts and outputs a PWM signal according to the data of the first flowmeter 17; when the collection flow value of the enrichment pipe 11 reaches a set value, the IO port of the single chip microcomputer outputs a low level, so that the relay 19 is disconnected, the electromagnetic valve is controlled to be closed, in addition, the single chip microcomputer closes the timer, PWM is not sent to the L298N motor driving chip any more, the air pump stops working, and the gas collection is completed.

In summary, the gas enrichment device 1 can firstly remove the moisture exhaled by the sampler through the main gas pipe 13, then open the collecting gas pipe 14 to adsorb the organic compounds with volatility at the tail part in the exhaled gas into the enrichment pipe 11, and then desorb the organic compound gas adsorbed into the enrichment pipe 11 by heating, and can be used for terahertz time-domain spectroscopy detection. Secondly, the gas enrichment device 1 can detect the flow of the collected gas in real time by arranging the first flowmeter 17 and feed the detected gas back to the first control unit 18, and the first control unit 18 judges whether the gas quantity collected in the enrichment pipe 11 reaches a set value or not according to the detected gas flow value. If the collected gas quantity reaches the set value, the first control unit 18 controls the valve 15 to close and the air extractor 16 to stop working respectively, so as to stop collecting the gas and realize quantitative gas quantity collection.

In another embodiment of the present application, the communicating pipe between the gas bomb 31 and the enrichment pipe 11 and the gas guiding pipe 33 are made of teflon and have an outer diameter of 6.35 mm. The heating device 32 is an AC-220V hot runner spring heating coil with a temperature sensing wire. The gas stored in the gas cylinder 31 is nitrogen or helium.

In another embodiment of the present application, the desorption device 3 includes a second flow meter 34, and the second flow meter 34 is connected between the gas cylinder 31 and the enrichment pipe 11, and is used for detecting the flow of the gas filled into the enrichment pipe 11 from the gas cylinder 31 in real time, so as to adjust the gas flow rate according to the detected value, ensure that the gas in the gas cylinder 31 is filled into the enrichment pipe 11 according to a predetermined flow rate, and purge the desorbed gas to be detected into the terahertz time-domain spectroscopy detection gas chamber 5. Optionally, the second flow meter 34 is a mass flow meter model MFC1000-500 sccm-A.

In another embodiment of the application, the desorption device 3 comprises a second control unit 35 and a solenoid valve 36. Electromagnetic valves 36 are arranged between the gas storage bottle 31 and the enrichment pipe 11 and between the enrichment pipe 11 and the terahertz time-domain spectroscopy detection gas chamber 5, and the electromagnetic valves 36 are electrically connected with the second control unit 35. After the enrichment pipe 11 is installed to the heating device 32, the second control unit 35 first controls to close the electromagnetic valve 36, and the enrichment pipe 11 is in a sealed state; heating the enrichment pipe 11 by a heating device 32 to desorb all volatile organic compounds adsorbed in the enrichment pipe 11; after the desorption is completed, the second control unit 35 controls to open the electromagnetic valve 36, the gas in the gas storage cylinder 31 is filled into the enrichment pipe 11, and the gas desorbed from the enrichment pipe 11 is purged into the terahertz time-domain spectroscopy detection gas chamber 5.

Further, a DC-24V two-position normally closed type electromagnetic valve is arranged between the gas storage cylinder 31 and the second flowmeter 34; a DC-24V two-position normally closed electromagnetic valve made of polytetrafluoroethylene is arranged between the second flowmeter 34 and the enrichment pipe 11.

The second control Unit 35 is a Micro Controller Unit (MCU) of model STM32F407ZET6, also called a single chip microcomputer, and outputs high and low levels through an IO port to control the solenoid valve 36.

The desorption device 3 comprises a relay 37 and a TTL-RS485 module 38, and the second control unit 35 is electrically connected to and controls the solenoid valve 36 through the relay 37. The second control unit 35 is in communication connection with the second flow meter 34 through the TTL-RS485 module 38, so that the gas flow value detected by the second flow meter 34 in real time is transmitted to the second control unit 35 through the TTL-RS485 module 38.

In another embodiment of the application, the desorption device 3 further comprises a temperature controller 39, the temperature controller 39 being connected between the second control unit 35 and the heating device 32. The second control unit 35 controls and adjusts the heating temperature of the heating device 32 by the temperature controller 39.

Further, the desorption device 3 further includes a rectifier 40, and since the output current of the temperature controller 39 is small, if the requirement of the heating device 32 on the current value cannot be met, the rectifier 40 may be additionally provided. A rectifier 40 is connected between the temperature controller 39 and the heating device 32. Optionally, the temperature controller 39 is a Q1300 series intelligent controller of precision instruments and meters of han and tang; the rectifier 40 adopts a model SCR40LA10LA intelligent solid state voltage regulator with 4-20mA input.

In another embodiment of the present application, the desorption apparatus 3 further includes a power supply 41 and a buck regulator module 42. The power source 41 is electrically connected to the voltage stabilizing and reducing module 42, and the second control unit 35 is electrically connected to the voltage stabilizing and reducing module 42.

Alternatively, the power source 41 is a 24V dc power source, and the power source 41 is electrically connected to the relay 37 to supply power to the relay 37. The power supply 41 supplies power to the second control unit 35 after the voltage stabilizing and reducing function of the voltage stabilizing and reducing module 42.

In another embodiment of the present application, the desorption device 3 further comprises an operation panel 43, optionally, the operation panel 43 is a TFT-LCD display screen. The power source 41 and the second control unit 35 are electrically connected to the operation panel 43. The user can control the operation of the entire desorption device 3 by means of the operating panel 43.

Further, the desorption device 3 further comprises a steering engine 44 and a steering engine driving module 45, the steering engine driving module 45 is connected between the voltage stabilizing and reducing module 42 and the second control unit 35, the steering engine driving module 45 is connected with the steering engine 44, and the steering engine 44 is used for driving the operation panel 43 to rotate. The second control unit 35 sends a corresponding command to the steering engine driving module 45 according to the angle of the operation panel 43, and the steering engine driving module 45 outputs a corresponding PWM wave to rotate the steering engine 44 by a corresponding angle, thereby adjusting the angle of the operation panel 43.

In another embodiment of the present application, the desorption device 3 further includes a first heat sink 46 and a second heat sink 47, and the first heat sink 46 is mounted on the heating device 32. Optionally, the first heat sink 46 is a high temperature resistant 220V axial fan. The second heat sink 47 is installed beside the second control unit 35 and electrically connected to the voltage stabilizing and reducing module 42. Alternatively, the second heat sink 47 may be a heat dissipation fan conventionally used in a notebook computer.

Taking the second control unit 35 as a single chip microcomputer as an example, the operation process of the desorption device 3 is as follows: after the power is on, the second heat dissipation device 47 starts to work to dissipate heat of the system control cabinet including the second control unit 35, the single chip outputs a low level, the relay 37 is disconnected, the electromagnetic valve 36 is closed, and the gas circuit is in a closed state; the single chip microcomputer writes the PID parameters and the preheating target temperature into the temperature controller 39 through the serial port, the temperature controller 39 starts to work and outputs 4-20mA current to the rectifier 40, the rectifier 40 adjusts the current of the heating device 32 according to the input current signal, and the single chip microcomputer obtains temperature data fed back by the sensor in real time according to a sensor communication protocol; clicking the start experiment on the operation panel 43 and selecting a key for cleaning the gas circuit, writing a heating target temperature into the temperature controller 39 through a serial port by the singlechip, increasing the temperature to a set temperature by the PID controller, carrying out desorption operation on the enrichment pipe 11, simultaneously returning temperature data at each moment to the singlechip through filtering processing, judging whether the temperature is reached by the singlechip according to the set temperature, stopping heating when the temperature is reached, and keeping the enrichment pipe 11 at a constant temperature; the flow rate parameters of the second flowmeter 34 are set on the operation panel 43, after the set time is reached, the electromagnetic valve for controlling the air pump is automatically opened, the gas in the gas storage cylinder 31 is blown out according to the set flow rate so as to push the volatile organic compound gas analyzed from the enrichment pipe 11 to enter the terahertz time-domain spectroscopy detection gas chamber 5, and the line cleaning process is carried out.

It is worth mentioning that according to different scenes, trigger modes, flow rates, heating temperatures and heating modes required by user experiments, IO (input/output) of the single chip microcomputer outputs different high and low level combinations to complete control over the relay 37, so as to control the electromagnetic valve 36, and the gas circuit of the enrichment pipe 11 is cleaned and the spectrum analysis is carried out on the auxiliary terahertz time-domain spectrum detection gas chamber 5. The heating device 32 can also be set to different temperature values to desorb all the volatile organic compound gas in the enrichment pipe 11.

The operation process of the processing device for detecting the exhaled air based on the terahertz time-domain spectroscopy detection system is as follows:

(1) A sampler blows air to the gas enrichment device 1 until the volume of the gas in the enrichment pipe 11 reaches a set value;

(2) The first control unit 18 controls the valve 15 to be closed, and the collecting air pipe 14 is closed;

(3) Taking out the enrichment pipe 11, loading into a desorption device 3, and checking the air tightness;

(4) Setting relevant desorption parameters on an operation panel 43, starting clicking, starting the heating device 32 to work, and desorbing the enrichment pipe 11;

(5) After the desorption is completed, the second control unit 35 controls the electromagnetic valve 36 to be opened, so that the gas in the gas bomb 31 is blown into the terahertz time-domain spectroscopy detection gas chamber 5.

The application provides a processing apparatus based on terahertz time-domain spectroscopy detection system detects expired gas, gathers the gas that the sampler exhaled through design gas enrichment device 1, makes the concentration of volatile organic compounds in the sample be higher than terahertz time-domain spectroscopy system's detection limit, adopts high resistant silicon to replace traditional design terahertz chip as the sensor substrate, when reduce cost, obtains more extensive spectrum sample signal and supplies follow-up data analysis. In addition, the processing apparatus for detecting the exhaled gas based on the terahertz time-domain spectroscopy detection system has the advantages of simplicity in operation, visual data, adjustable gas flow rate and the like.

The above description is only exemplary of the present application and should not be taken as limiting the present application, as any modification, equivalent replacement, or improvement made within the spirit and principle of the present application should be included in the protection scope of the present application.

Claims (10)

1. A processing apparatus for detecting exhaled air based on a terahertz time-domain spectroscopy system is characterized by comprising:

the gas enrichment device comprises an enrichment pipe, and the enrichment pipe is used for collecting the exhaled gas of the human body and adsorbing and concentrating the exhaled gas in the enrichment pipe;

the desorption device comprises a gas storage bottle, a heating device and a gas guide pipe, the heating device is used for installing the enrichment pipe and heating the enrichment pipe, after the enrichment pipe is installed on the heating device, one end of the enrichment pipe is communicated with the gas storage bottle, and the other end of the enrichment pipe is communicated with one end of the gas guide pipe;

the terahertz time-domain spectroscopy detection gas chamber is connected with the other end of the gas guide tube, and a sensor adopting a high-resistance silicon wafer substrate is arranged in the terahertz time-domain spectroscopy detection gas chamber.

2. The processing device for detecting the exhaled gas based on the terahertz time-domain spectroscopy system as claimed in claim 1, wherein the gas enrichment device comprises a blowing nozzle, a main gas pipe, a collection gas pipe, a valve and an air extractor, one end of the main gas pipe and one end of the collection gas pipe are both communicated with the blowing nozzle, one end of the enrichment pipe is communicated with the other end of the collection gas pipe through the valve, and the other end of the enrichment pipe is communicated with the air extractor through the valve.

3. The terahertz time-domain spectroscopy based system for detecting exhaled breath of claim 2, wherein the gas enrichment device comprises a first flow meter, and the first flow meter is connected between the enrichment tube and the gas exhaust device.

4. The processing device for detecting the exhaled gas based on the terahertz time-domain spectroscopy system as claimed in claim 3, wherein the gas enrichment device comprises a first control unit and a relay, and the valve is a solenoid valve and is connected with the first control unit through the relay.

5. The processing apparatus for detecting exhaled breath based on the terahertz time-domain spectroscopy system as claimed in claim 4, wherein the gas enrichment apparatus comprises a power source and a voltage stabilizing and dropping module, the power source is electrically connected to the voltage stabilizing and dropping module, and the first control unit is electrically connected to the voltage stabilizing and dropping module.

6. The processing device for detecting the exhaled gas based on the terahertz time-domain spectroscopy system as claimed in claim 4, wherein the gas enrichment device comprises a driving module, and the first control unit controls the gas exhausting device through the driving module.

7. The processing device for detecting the exhaled air based on the terahertz time-domain spectroscopy system as claimed in any one of claims 1 to 6, wherein the enrichment tube is one of a Tenax-TA filling tube, a carbon molecular sieve filling tube, a Tenax-TA and a carbon molecular sieve mixed filling tube.

8. The terahertz time-domain spectroscopy system-based exhaled gas detection processing device of claim 1, wherein the desorption device comprises a second flow meter connected between the gas bomb and the enrichment tube.

9. The processing apparatus for detecting exhaled air based on the terahertz time-domain spectroscopy system as claimed in claim 1, wherein the desorption apparatus comprises a second control unit and solenoid valves, the solenoid valves are disposed between the gas bomb and the enrichment tube, and between the enrichment tube and the terahertz time-domain spectroscopy detection gas chamber, and the solenoid valves are electrically connected to the second control unit.

10. The terahertz time-domain spectroscopy system-based exhaled gas detection processing device of claim 1, wherein the desorption device comprises a second control unit and a temperature controller, and the temperature controller is connected between the second control unit and the heating device.

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