CN218356471U - Self-expanding heart valve stent - Google Patents
Self-expanding heart valve stent Download PDFInfo
- Publication number
- CN218356471U CN218356471U CN202221105878.8U CN202221105878U CN218356471U CN 218356471 U CN218356471 U CN 218356471U CN 202221105878 U CN202221105878 U CN 202221105878U CN 218356471 U CN218356471 U CN 218356471U
- Authority
- CN
- China
- Prior art keywords
- self
- expanding
- arc
- heart valve
- arms
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 210000003709 heart valve Anatomy 0.000 title claims abstract description 199
- 230000003014 reinforcing effect Effects 0.000 claims abstract description 45
- 238000007906 compression Methods 0.000 description 11
- 230000006835 compression Effects 0.000 description 10
- 239000002131 composite material Substances 0.000 description 6
- 210000000709 aorta Anatomy 0.000 description 5
- 230000008901 benefit Effects 0.000 description 4
- 239000000463 material Substances 0.000 description 4
- 210000001765 aortic valve Anatomy 0.000 description 3
- 238000002513 implantation Methods 0.000 description 3
- 239000003550 marker Substances 0.000 description 3
- HZEWFHLRYVTOIW-UHFFFAOYSA-N [Ti].[Ni] Chemical compound [Ti].[Ni] HZEWFHLRYVTOIW-UHFFFAOYSA-N 0.000 description 2
- 238000004873 anchoring Methods 0.000 description 2
- 238000005452 bending Methods 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 229910001000 nickel titanium Inorganic materials 0.000 description 2
- 238000001356 surgical procedure Methods 0.000 description 2
- 208000002251 Dissecting Aneurysm Diseases 0.000 description 1
- 206010067171 Regurgitation Diseases 0.000 description 1
- 208000007536 Thrombosis Diseases 0.000 description 1
- 230000001154 acute effect Effects 0.000 description 1
- 230000000151 anti-reflux effect Effects 0.000 description 1
- 206010002895 aortic dissection Diseases 0.000 description 1
- 238000010009 beating Methods 0.000 description 1
- 230000017531 blood circulation Effects 0.000 description 1
- 210000004375 bundle of his Anatomy 0.000 description 1
- 230000000747 cardiac effect Effects 0.000 description 1
- 238000005336 cracking Methods 0.000 description 1
- 238000001125 extrusion Methods 0.000 description 1
- 230000002349 favourable effect Effects 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- 238000009434 installation Methods 0.000 description 1
- 230000009545 invasion Effects 0.000 description 1
- 230000000149 penetrating effect Effects 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 238000009958 sewing Methods 0.000 description 1
- 125000006850 spacer group Chemical group 0.000 description 1
- 230000008733 trauma Effects 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
- A61F2/2412—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body with soft flexible valve members, e.g. tissue valves shaped like natural valves
- A61F2/2418—Scaffolds therefor, e.g. support stents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
- A61F2/2442—Annuloplasty rings or inserts for correcting the valve shape; Implants for improving the function of a native heart valve
- A61F2/2454—Means for preventing inversion of the valve leaflets, e.g. chordae tendineae prostheses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
- A61F2/2442—Annuloplasty rings or inserts for correcting the valve shape; Implants for improving the function of a native heart valve
- A61F2/2463—Implants forming part of the valve leaflets
Landscapes
- Health & Medical Sciences (AREA)
- Cardiology (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Transplantation (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Vascular Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Prostheses (AREA)
Abstract
The utility model discloses a self-expanding heart valve support, the near end of which comprises a fastener for fixing the artificial heart valve leaflet and a reinforcing net arranged between the near end and the far end. The reinforcing net can comprise a first self-expansion arc, a second self-expansion arc and a third self-expansion arc which are arranged in sequence along the direction from the far end to the near end of the self-expansion heart valve support, wherein the first self-expansion arc is fixedly connected with the fastener and protrudes towards the far end of the heart valve support; two ends of the second self-expansion arc are respectively and fixedly connected to the first self-expansion arc and protrude towards the proximal end of the heart valve stent; the third self-expanding arc is fixedly connected with the fastener and protrudes towards the distal end of the heart valve stent, and a gap exists between the second self-expanding arc and the third self-expanding arc. The self-expanding heart valve stent described herein enables the self-expanding heart valve stent to expand into place.
Description
Technical Field
The utility model relates to the technical field of medical equipment, concretely relates to from expanding heart valve support.
Background
Since the way of performing surgery via a catheter has many advantages such as less trauma and fast recovery, more and more surgeries are beginning to be performed via a catheter. Aortic valve replacement was also changed from the earlier surgical approach to transcatheter aortic valve replacement. Cardiac valve stents are important instruments for transcatheter aortic valve replacement and are often fabricated from nickel titanium tubing. When the operation is performed, the heart valve stent sutured with the artificial heart valve leaflet is usually firstly squeezed and then conveyed to a proper position through a conveyor, and then the heart valve stent is released to expand into a cylinder shape so as to drive the artificial heart valve leaflet to open. However, prior art heart valve stents tend to be difficult to expand into position.
Chinese patent publication No. CN102413793B, entitled "stent for positioning and anchoring of a valve prosthesis at an implantation site in a heart of a patient" discloses an expandable stent comprising a plurality of positioning arches configured to be located within pockets on a native heart valve and on a first side of a plurality of native heart valve leaflets, and a plurality of retaining arches configured to be located on a second side of the plurality of native heart valve leaflets opposite the first side. The retaining arc is divided by a plurality of curved edges into a plurality of arm segments that are interconnected to form a retaining arc arm that is in a straight line when the stent is in an unexpanded state. Each arm of the retaining arc has a shape that matches a leaflet of a valvular prosthesis attached to the stent. However, in the heart valve stent disclosed in the prior art, the native heart valve leaflets are directly clamped between the positioning members and the fastening arcs, and there is a risk that the native heart valve leaflets invade the prosthetic heart valve leaflets.
Accordingly, there is a continuing need in the art to develop a heart valve stent that can be expanded into place and that avoids the intrusion of native heart valve leaflets into the prosthetic heart valve leaflets.
SUMMERY OF THE UTILITY MODEL
It is an object of the present application to provide a self-expanding heart valve stent that can be expanded into place. Specifically, in the self-expanding heart valve stent described herein, a reinforcing mesh is provided between the fastener of the self-expanding heart valve stent and the distal end of the self-expanding heart valve stent, and the reinforcing mesh may include three self-expanding arcs arranged in sequence from top to bottom, and the width of the lowermost self-expanding arc is the largest and the span is the largest, and this structure solves the problem that the radial support force between adjacent fastening arcs is weak and the self-expansion is not in place.
In order to achieve the above purpose, the utility model provides a technical scheme as follows.
In a first aspect, the present application provides a self-expanding heart valve stent comprising a self-expanding heart valve stent distal end that is proximal to an apex of the heart when the self-expanding heart valve stent is in an expanded state and a self-expanding heart valve stent proximal end that is distal to the apex of the heart when the self-expanding heart valve stent is in an expanded state, characterized in that the self-expanding heart valve stent proximal end comprises connectors and fasteners disposed between adjacent connectors, the fasteners being for securing prosthetic heart valve leaflets;
wherein the fastener comprises a first fastening arc, a second fastening arc, and a fastener distal end connecting the first fastening arc and the second fastening arc, the first fastening arc is fixedly connected to a first connector, the second fastening arc is fixedly connected to a second connector, and the first connector is adjacent to the second connector;
the distal end of the self-expanding heart valve stent comprises a clamping end, a reinforcing net is arranged between the clamping end and the fasteners, the distal end of the reinforcing net is fixed to the clamping end, and the proximal end of the reinforcing net is fixedly connected between different fastening arcs of adjacent fasteners;
wherein the reinforcing mesh comprises a first self-expansion arc, a second self-expansion arc and a third self-expansion arc which are sequentially arranged along the direction from the far end of the self-expansion heart valve stent to the near end of the self-expansion heart valve stent, one end of the first self-expansion arc is fixedly connected with the first fastening arc of the fastening piece, the other end of the first self-expansion arc is fixedly connected with the second fastening arc of the adjacent fastening piece, and the first self-expansion arc, the second self-expansion arc and the third self-expansion arc are protruded towards the far end of the heart valve stent; two ends of the second self-expansion arc are respectively fixedly connected to the first self-expansion arc and protrude towards the proximal end of the heart valve stent; one end of the third self-expanding arc is fixedly connected with the first fastening arc of the fastener, the other end of the third self-expanding arc is fixedly connected with the second fastening arc of the adjacent fastener and protrudes towards the far end of the heart valve stent, and a gap exists between the second self-expanding arc and the third self-expanding arc.
In one embodiment of the first aspect, the width of the first self-expanding arc is greater than the width of the second self-expanding arc and the width of the third self-expanding arc.
In one embodiment of the first aspect, the span of the first self-expanding arc is greater than the span of the second self-expanding arc and the span of the third self-expanding arc.
In one embodiment of the first aspect, the first self-expanding arc is composed of two first self-expanding arms, the proximal ends of the two first self-expanding arms are fixedly connected with the middle positions of the two fastening arcs respectively, the distal ends of the two first self-expanding arms are connected with each other, and the connecting part of the distal ends of the two first self-expanding arms is also fixedly connected with the clamping position end;
the second self-expansion arc is composed of two second self-expansion arms, the far ends of the two second self-expansion arms are respectively fixedly connected with the middle positions of the two first self-expansion arms, and the near ends of the two second self-expansion arms are connected;
the third self-expansion arc is composed of two third self-expansion arms, the near ends of the two third self-expansion arms are fixedly connected with the positions, close to the near ends, of the two fastening arcs respectively, and the far ends of the two third self-expansion arms are connected.
In one embodiment of the first aspect, the proximal ends of the two third self-expanding arms are fixedly connected to 1/4 of the proximal ends of the two fastening arcs, respectively.
In one embodiment of the first aspect, the length of the second self-expanding arm is no greater than half the length of the first self-expanding arm.
In one embodiment of the first aspect, the third self-expanding arm has a length no greater than half the length of the second self-expanding arm.
In one embodiment of the first aspect, the second self-expanding arm has a length that is half the length of the first self-expanding arm, and the third self-expanding arm has a length that is half the length of the second self-expanding arm.
In one embodiment of the first aspect, when the self-expanding heart valve stent is in the expanded state, a first fastening arch of a fastener forms a first rounded corner with a second fastening arch of an adjacent fastener, the first self-expanding arch has a second rounded corner, and the third self-expanding arch has a third rounded corner. In this embodiment, the third fillet is no greater than the first fillet formed by its corresponding adjacent securing arc, and the second fillet is greater than the first and third fillets.
In one embodiment of the first aspect, the reinforcing mesh further comprises additional self-expanding arcs disposed inside the second self-expanding arc or inside the third self-expanding arc, and the sum of the number of self-expanding arcs of the reinforcing mesh is less than or equal to 5.
In one embodiment of the first aspect, the reinforcing mesh further includes a fourth self-expanding arc disposed inside the second self-expanding arc, the fourth self-expanding arc is formed by two fourth self-expanding arms, distal ends of the two fourth self-expanding arms are fixedly connected with the two first self-expanding arms, respectively, and proximal ends of the two fourth self-expanding arms are connected. The width of the fourth self-expanding arm is smaller than the width of the self-expanding arm of the first self-expanding arc and not greater than the width of the self-expanding arm of the second self-expanding arc.
In one embodiment of the first aspect, the reinforcing mesh further includes a fourth self-expanding arc disposed inside the second self-expanding arc, the fourth self-expanding arc is formed by two fourth self-expanding arms, proximal ends of the two fourth self-expanding arms are fixedly connected with the two second self-expanding arms, respectively, and distal ends of the two fourth self-expanding arms are connected. The width of the fourth self-expanding arm is smaller than the width of the self-expanding arm of the first self-expanding arc and not greater than the width of the self-expanding arm of the second self-expanding arc.
In one embodiment of the first aspect, when the self-expanding heart valve stent is in the expanded state, the fourth self-expanding arcs have a fourth fillet that is no greater than the proximal fillet formed by the second self-expanding arcs.
In an embodiment of the first aspect, the reinforcing mesh further includes a fifth self-expanding arc disposed inside the third self-expanding arc, the fifth self-expanding arc is formed by two fifth self-expanding arms, proximal ends of the two fifth self-expanding arms are fixedly connected to positions of the two fastening arcs near the proximal ends, respectively, and distal ends of the two fifth self-expanding arms are connected to each other. The width of the fifth self-expanding arm is not greater than the width of the self-expanding arm of the third self-expanding arc.
In one embodiment of the first aspect, the reinforcing mesh further comprises a fifth self-expanding arc disposed inside the third self-expanding arc, the fifth self-expanding arc being formed by two fifth self-expanding arms, distal ends of the two fifth self-expanding arms being fixedly connected to the two third self-expanding arcs, respectively, and proximal ends of the two fifth self-expanding arms being connected to each other. The width of the fifth self-expanding arm is not greater than the width of the self-expanding arm of the third self-expanding arc.
In one embodiment of the first aspect, the third self-expanding arc has a third rounded corner and the fifth self-expanding arc has a fifth rounded corner when the self-expanding heart valve stent is in the expanded state, the fifth rounded corner being no larger than the third rounded corner.
In one embodiment of the first aspect, the self-expanding heart valve support further comprises a support member and a positioning member disposed between the adjacent connecting members, wherein the support member comprises a first support arm, a second support arm, and a support member distal end connecting the first support arm and the second support arm, the first support arm is fixedly connected to the first connecting member, the second support arm is fixedly connected to the second connecting member, and the first connecting member is adjacent to the second connecting member. In this embodiment, the positioning element includes a first positioning arm, a second positioning arm, and a positioning element distal end connecting the first positioning arm and the second positioning arm, the first positioning arm is fixedly connected to a first connecting element, the second positioning arm is fixedly connected to a second connecting element, and the first connecting element is adjacent to the second connecting element. In this embodiment, the positioning member is closer to the self-expanding cardiac valve stent distal end than the support, the fastener is closer to the self-expanding cardiac valve stent distal end than the positioning member, the support distal end and the positioning member distal end are rods protruding toward the self-expanding cardiac valve stent distal end, the support is disposed on one side of a native cardiac valve leaflet, and the positioning member is disposed on the other side of the native cardiac valve leaflet.
Compared with the prior art, the beneficial effect of this application lies in:
(1) Arranging a reinforcing net between a fastener at the proximal end of the self-expanding heart valve stent and a clamping end at the distal end of the self-expanding heart valve stent, wherein the reinforcing net comprises three self-expanding arcs arranged in sequence from the proximal end to the distal end, the width of the lowermost self-expanding arc is the largest, the span is the largest, and the required radial expansion force can be provided, so that the self-expanding heart valve stent is expanded in place;
(2) A support member is disposed at a proximal end of the self-expanding heart valve stent such that the native heart valve leaflets are sandwiched between the support member and the positioning member and the prosthetic heart valve leaflets are sandwiched between the positioning member and the fastening member such that the native heart valve leaflets are prevented from intruding the prosthetic heart valve leaflets. In this embodiment, the native leaflets have upper portions joined by a support and a positioning member and lower portions clamped by a positioning member and a fastener. The prosthetic leaflet is attached to the heart valve stent along fasteners with the native leaflet being outside the fasteners and the prosthetic leaflet being inside the fasteners.
Drawings
The technical features and advantages of the present invention are more fully understood by reference to the following detailed description in conjunction with the accompanying drawings.
FIG. 1 shows a perspective view of a self-inflating heart valve stent in an expanded state according to an embodiment of the present application.
FIG. 2 shows a deployed view of the self-inflating heart valve stent of FIG. 1.
Fig. 3 shows a partial enlarged view of the area a in fig. 2.
Fig. 4 shows a partial enlarged view of the area B in fig. 2.
FIG. 5 shows a perspective view of a self-inflating heart valve stent in an expanded state according to another embodiment.
Fig. 6 shows a deployment view of the anti-reflux cardiac stent shown in fig. 5.
Fig. 7 shows a partial enlarged view of the area B in fig. 6.
Detailed Description
Unless otherwise defined, technical or scientific terms used herein shall have the ordinary meaning as is understood by those of ordinary skill in the art to which the invention belongs.
In the description of the present invention, it is to be understood that the terms "center", "longitudinal", "lateral", "up", "down", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", and the like, indicate orientations or positional relationships based on the orientations or positional relationships shown in the drawings, and are used merely for convenience of description and for simplicity of description, and do not indicate or imply that the device or element being referred to must have a particular orientation, be constructed and operated in a particular orientation, and therefore, should not be construed as limiting the present invention.
Furthermore, the terms "first", "second", etc. are used for descriptive purposes only and are not to be construed as indicating or implying relative importance or implicitly indicating the number of technical features indicated. Thus, a feature defined as "first," "second," etc. may explicitly or implicitly include one or more of that feature. In the description of the present invention, "a plurality" means two or more unless otherwise specified.
In the description of the present invention, it is to be noted that, unless otherwise explicitly specified or limited, the terms "mounted," "connected," and "connected" are to be construed broadly, e.g., as being connected, detachably connected, or integrally connected; can be mechanically or electrically connected; they may be connected directly or indirectly through intervening media, or they may be interconnected between two elements. The specific meaning of the above terms in the present invention can be understood by those of ordinary skill in the art through specific situations.
As used herein, when describing the heart valve stent, "proximal" refers to a side of the delivery device or a side in the direction of the user-manipulated end when the heart valve stent assumes an expanded state. Accordingly, "distal" refers to the side of the heart valve stent that is distal from the delivery device or away from the direction of the user-manipulated end when the heart valve stent assumes an expanded state. In the present application, when describing the heart valve stent, "proximal" refers to a side of the heart valve stent that is close to the apex of the heart when the heart valve stent assumes an expanded state. Accordingly, "distal" refers to the side of the heart valve stent that is distal to the apex of the heart when the heart valve stent is in an expanded state. Because the cardiac valve stent described herein is delivered by a catheter through the aorta, the distal and proximal ends refer to the same location, and the proximal and distal ends refer to the same location, but this does not preclude transapical implantation, but rather the cardiac valve stent is described herein as being delivered by a catheter through the aorta.
Example 1
The present embodiments relate to a self-expanding heart valve stent having a proximal end including a support member, a positioning member, and a fastener disposed between the attachment members, a distal end including a capture end, and a reinforcing mesh disposed between the fastener and the capture end. The reinforcing net comprises three self-expansion arcs which are arranged from the near end to the far end in sequence, and the width and the span of the self-expansion arc which is closest to the far end are longest, so that enough radial expansion force can be provided, and the self-expansion heart valve stent can be expanded in place. In addition, the self-expanding heart valve stent of the embodiment can clamp the distal end of the native heart valve leaflet between the support member and the positioning member and clamp the proximal end of the native heart valve leaflet between the positioning member and the fastening member, thereby preventing the native heart valve leaflet from invading the artificial heart valve leaflet.
Referring first to fig. 1-4, the heart valve stent of the present embodiment may include a distal heart valve stent end that is proximal to the apex of the heart when the heart valve stent is in the expanded state and a proximal heart valve stent end that is distal to the apex of the heart when the heart valve stent is in the expanded state. The proximal end of the heart valve stent may comprise connectors 14 and supports 11, positioning members 12 and fasteners 13 disposed between adjacent connectors. The supporting member 11 and the positioning member 12 can be used to fix the native heart valve leaflet, and the fastening member 13 can be used to fix the artificial heart valve leaflet, and the fixed artificial heart valve leaflet herein can be directly fixed, or can be indirectly fixed through other media, such as a fastening member to fix a covering film, and then the artificial heart valve leaflet is fixed through the covering film.
In this embodiment, the support member may include a first support arm 111, a second support arm 112, and a support member distal end 113 connecting the first support arm 111 and the second support arm 112. The first support arm 111 is fixedly connected to a first connector, and the second support arm 112 is fixedly connected to a second connector, the first connector being adjacent to the second connector. Similarly, the positioning member 12 may include a first positioning arm 121, a second positioning arm 122, and a positioning member distal end 123 connecting the first positioning arm and the second positioning arm. The first positioning arm 121 is fixedly connected to a first connecting member, and the second positioning arm 122 is fixedly connected to a second connecting member, the first connecting member being adjacent to the second connecting member. Further, the fastener 13 comprises a first fastening arc 131, a second fastening arc 132 and a fastener distal end 133 connecting the first fastening arc and the second fastening arc. The first fastening arc is fixedly connected to a first connecting piece, the second fastening arc is fixedly connected to a second connecting piece, and the first connecting piece is adjacent to the second connecting piece.
In this embodiment, the positioning member 12 is closer to the distal end of the heart valve holder than the support member 11, and the fastening member 13 is closer to the distal end of the heart valve holder than the positioning member 12. The support distal end 113 and the positioning member distal end 123 are rods that project towards the distal end of the heart valve stent. The support member 11 is disposed on one side of the native heart valve leaflet and the positioning member 12 is disposed on the other side of the native heart valve leaflet.
Compared with the traditional heart valve support, the heart valve support also comprises a support part 11, so that the native heart valve leaflets can be clamped between the support part 11 and a positioning part 12, the support part 11 prevents the native heart valve leaflets from invading the artificial heart valve leaflets, and the native heart valve leaflets are clamped by the support part and the positioning part, so that the clamping is relatively firmer, meanwhile, the support part also facilitates the heart valve support to be capable of smoothly self-expanding, and the radial force during self-expansion is increased.
In a specific embodiment, referring to fig. 2, the first and second support arms are linear when the heart valve stent is in a compressed state. The first and second positioning arms are linear when the heart valve stent is in a compressed state. The first positioning arm and the second positioning arm are designed to be linear so as to facilitate compression, and when the first positioning arm and the second positioning arm are fully compressed, the occupied space is minimum, namely, the adjacent first supporting arm and the second supporting arm are fully close to each other. The linear structure can ensure that the first positioning arm and the second positioning arm do not interfere with each other when being compressed, so that the first positioning arm and the second positioning arm are linear so as to be close to each other sufficiently and not to interfere with each other when being compressed. In addition, the stent is formed by cutting a nickel-titanium tube, but the adopted material can be any material which can be implanted into a human body, the linear design is also beneficial to processing, the processing path is shortened, and the processing cost is reduced.
In one embodiment, the distal end of the positioning member has a parabolic structure, so that the contact stress of the positioning member and the sinus floor is reduced, and the valve ring is prevented from cracking.
In one embodiment, the width of the fastener 13 is wider than the width of the support member 11 and the spacer member 12, which is primarily the width of the rod, to provide strong support.
In one embodiment, when the heart valve stent is in the expanded state, the support member has a first opening angle to facilitate clamping of native leaflets between the support member and the positioning member, the positioning member has a second opening angle, the second opening angle is 4 ° to 14 °, and the first opening angle is smaller than the second opening angle. The positioning piece 12 and the fastener 13 form a certain opening angle, so that the positioning piece 12 can catch the valve leaflets conveniently, and the operation difficulty is reduced. The positioning element 12 can be used for preventing the valve ventricle from displacing, so that the distal end of the artificial heart valve leaflet is aligned with the native heart valve leaflet, the artificial heart valve leaflet can restore the native heart valve leaflet to the maximum extent, and meanwhile, the artificial heart valve leaflet can be kept at the position of the native heart valve leaflet, so that the artificial heart valve leaflet can well replace the native heart valve leaflet, the influence on blood flow is reduced, the occurrence of thrombus is reduced, the positioning element 12 and the fastening element 13 can clamp the native heart valve leaflet due to the arrangement of the second opening angle of 4-14 degrees, the native heart valve leaflet is prevented from moving freely, and meanwhile, the native heart valve leaflet is tightly attached to the support, and the paravalvular leakage is reduced.
In one embodiment, the perpendicular distance between the distal end of the positioning member closest to the distal end of the heart valve stent and the distal-most portion of the distal end of the heart valve stent (i.e., the capture end 16 described below) is 4mm to 8mm, preferably 6mm.
In one embodiment, the distal end of the card end is flared proximally relative to the card end, and the distal end of the card end is flared proximally at an angle of 6 ° to 14 ° relative to the card end. The reason why the flaring is needed is to prevent the self-expanding heart valve stent from displacing towards the aorta and to perform anchoring function. At the same time, the reason why the excessive angle cannot be generated is to prevent the his bundle from being touched, thereby affecting the normal beating of the heart and endangering life.
In one embodiment, referring to fig. 1 and 2, the distal end of the self-expanding heart valve stent further comprises a retaining end 16 and a reinforcing mesh 15, and an open structure 17 is present between the retaining end 16 and the reinforcing mesh 15. In this embodiment, the number of diamond-shaped squares at the clamping end 16 is 18, which effectively increases the compressibility of the heart valve stent, and the rod widths of the diamond-shaped squares are gradually changed (the width is thin at the middle and two ends) to optimize the fatigue resistance of the stent. In addition, because the heart valve support only comprises 18 diamond-shaped grids, only one reinforcing net 15 is needed to connect the clamping ends between the adjacent fastening arcs of the heart valve support, a large number of hollowed-out parts can be formed, the weight of the heart valve support is effectively reduced, the heart valve support is convenient to compress, and the rod width of the diamond-shaped grids is gradually changed (the middle part is thin and the two ends are wide) so as to optimize the fatigue resistance of the support. In addition, the presence of the reinforcing mesh 15 can not only increase the structural strength of the middle part of the stent, but also isolate the autologous valve leaflets to prevent the invasion of the artificial heart valve leaflets.
Next, referring to fig. 3 and 4, further technical features of the card end 16 and the reinforcing mesh 15 will be described in more detail.
In one embodiment, referring to fig. 3, a reinforcing mesh 15 is disposed between the capture end 16 and the fasteners 13, a distal end of the reinforcing mesh 15 is secured to the capture end 16, and a proximal end of the reinforcing mesh 15 is fixedly attached between different fastening arcs of adjacent fasteners 13.
The reinforcing mesh may comprise a first self-expanding arc 151, a second self-expanding arc 152 and a third self-expanding arc 153 arranged in that order in a direction from the distal end of the self-expanding heart valve stent to the proximal end of the self-expanding heart valve stent. One end of the first self-expansion arc is fixedly connected with the first fastening arc of the fastener, and the other end of the first self-expansion arc is fixedly connected with the second fastening arc of the adjacent fastener and protrudes towards the far end of the heart valve support. Two ends of the second self-expansion arc are respectively and fixedly connected to the first self-expansion arc and are protruded towards the proximal end of the heart valve support. One end of the third self-expanding arc is fixedly connected with the first fastening arc of the fastener, and the other end of the third self-expanding arc is fixedly connected with the second fastening arc of the adjacent fastener and protrudes towards the far end of the heart valve support. A gap exists between the second self-expanding arc and the third self-expanding arc.
In one embodiment, the width of the first self-expanding arc 151 is greater than the width of the second self-expanding arc 152 and the third self-expanding arc 153. The size of the first self-expanding arc 151 is largest relative to the sizes of the second self-expanding arc 152 and the third self-expanding arc 153, and the span is also largest, so that the first self-expanding arc 151 needs to provide a larger radial supporting force, thereby ensuring the stable supporting performance. Therefore, the width of the first self-expanding arcs 151 is wide, and the reinforcing net formed by the first self-expanding arcs 151, the second self-expanding arcs 152 and the third self-expanding arcs 153 can prevent the native heart valve leaflets from invading the artificial heart valve leaflets, and solve the problems that the radial supporting force between adjacent fastening arcs is weak and the self-expansion is not in place.
In one embodiment, the first self-expanding arc 151 is composed of two first self-expanding arms 1511, the proximal ends of the two first self-expanding arms 1511 are fixedly connected with the middle positions of the two fastening arcs respectively, the distal ends of the two first self-expanding arms 1511 are connected with each other, and the connection part is also fixedly connected with the clamping position end 16.
In one embodiment, the second self-expanding arc 152 is composed of two second self-expanding arms 1521, the distal ends of the two second self-expanding arms 1521 are fixedly connected with the middle positions of the two first self-expanding arms 1511, respectively, and the proximal ends of the two second self-expanding arms 1521 are connected. The length of the second self-expanding arm 1521 is no greater than half the length of the first self-expanding arm 1511. Preferably, the length of the second self-expanding arm 1521 is half the length of the first self-expanding arm 1511.
In one embodiment, the third self-expanding arc 153 is formed by two third self-expanding arms 1531, wherein the proximal ends of the two third self-expanding arms 1531 are fixedly connected to 1/4 of the proximal ends of the two fastening arcs, respectively, and the distal ends of the two third self-expanding arms 1531 are connected. The length of the third self-expanding arm 1531 is no greater than half the length of the second self-expanding arm 1521. Preferably, the length of the third self-expanding arm 1531 is half the length of the second self-expanding arm 1521.
The design can realize reasonable utilization of space, and the structure of the pipe can be realized by one pipe.
In this embodiment, when the heart valve stent is in the expanded state, the first fastening arcs 131 of the fasteners 13 form first rounded corners 154 with the second fastening arcs 132 of adjacent fasteners, the second self-expanding arcs 151 have second rounded corners 155, and the third self-expanding arcs 153 have third rounded corners 156. The third fillet 156 is no greater than the first fillet 154 formed by its corresponding adjacent fastening arc. Because the closer the connection to the proximal end of the fastener, the less space there is, i.e. the greater the amount of material, i.e. the less material free space. Assuming that the third rounded corner 156 is larger than the first rounded corner 154, when the self-expanding heart valve stent is compressed, the two third self-expanding arms will approach closer to each other than the two fastening arcs because the two third self-expanding arms are between the two fastening arcs, so the two third self-expanding arms will approach very close to each other, and therefore the excessive third rounded corner 156 will prevent the two third self-expanding arms from approaching each other and even block the adjacent fastening arcs from approaching, thereby making the compression of the regurgitation stent difficult, and even the excessive third rounded corner 156 will break due to the excessive compression during the compression process. The first self-expanding arc 151 corresponding to the second fillet 155 has a larger span, so that it is necessary to provide a sufficient supporting force to satisfy the larger span, so that the second fillet 155 is larger than the first fillet 154 and the third fillet 156. For a similar reason to the magnitude relationship between the third fillet 156 and the first fillet 154, the second fillet 155 is a fillet formed by the junction of two second self-expanding arms 1521 that is larger than the corresponding second self-expanding arc 152.
In the present embodiment, the first self-expanding arc 151, the second self-expanding arc 152, and the third self-expanding arc 153 are provided, but this does not represent that the reinforcing mesh is provided with only three self-expanding arcs.
In one embodiment, a fourth self-expanding arc (not shown) may be provided inside the second self-expanding arc 152, and when the self-expanding heart valve stent is in the expanded state, the fillet formed by the junction of the two self-expanding arms of the fourth self-expanding arc is not greater than the fillet formed by the junction of the two second self-expanding arms 1521 of the corresponding second self-expanding arc 152, and the width of the self-expanding arm of the fourth self-expanding arc is not greater than the width of the self-expanding arm of the first self-expanding arc connected thereto, thereby reducing the space occupancy rate.
In another embodiment, the reinforcing mesh 15 further comprises a fourth self-expanding arc (not shown) disposed inside the second self-expanding arc 152, the fourth self-expanding arc being formed by two fourth self-expanding arms, distal ends of the two fourth self-expanding arms being fixedly connected to the two first self-expanding arms, respectively, and proximal ends of the two fourth self-expanding arms being connected. The width of the fourth self-expanding arm is smaller than the width of the self-expanding arm of the first self-expanding arc 151 and not larger than the width of the self-expanding arm of the second self-expanding arc 152.
In another embodiment, a fourth self-expanding arc (not shown) may be located inside the second self-expanding arc, and the fourth self-expanding arc may be formed by two fourth self-expanding arms, wherein the proximal ends of the two fourth self-expanding arms are fixedly connected to the two second self-expanding arms, and the distal ends of the two fourth self-expanding arms are connected to the proximal ends of the two fourth self-expanding arms. A width of the fourth self-expanding arm is less than a width of the self-expanding arm of the first self-expanding arc and not greater than a width of the self-expanding arm of the second self-expanding arc. In another embodiment, a new self-expanding arc may be further disposed within the fourth self-expanding arc, the total number of self-expanding arcs of the self-expanding heart valve stent being no more than five.
In one embodiment, a fifth self-expanding arc (not shown) may be disposed inside the third self-expanding arc 153, the third self-expanding arc having a third rounded corner when the self-expanding heart valve stent is in the expanded state, the fifth self-expanding arc having a fifth rounded corner, the fifth rounded corner being not larger than the third rounded corner, and the width of the self-expanding arms of the fifth self-expanding arc being not larger than the width of the self-expanding arms of the first self-expanding arc and/or the fastening arcs of the fasteners connected thereto, thereby reducing the space occupancy rate.
In another embodiment, a fifth self-expanding arc (not shown) may be disposed inside the third self-expanding arc 153, but the total number of the self-expanding arcs of the reinforcing mesh does not exceed 5 so as not to affect the compression performance of the self-expanding heart valve stent. The fifth self-expanding arc may have a fifth rounded corner when the self-expanding heart valve stent is in the expanded state, the fifth rounded corner being no larger than the first rounded corner for similar reasons as the third self-expanding arc. The width of the fifth self-expanding arc is no greater than the width of a fastening arc of a fastener connected to the fifth self-expanding arc.
In another embodiment, a fifth self-expanding arc (not shown in the figure) may be located inside the third self-expanding arc, and the fifth self-expanding arc is composed of two fifth self-expanding arms, wherein the proximal ends of the two fifth self-expanding arms are fixedly connected with the two fastening arcs near the proximal ends, and the distal ends of the two fifth self-expanding arms are connected. The width of the fifth self-expanding arm is no greater than the width of the self-expanding arm of the third self-expanding arc.
In another embodiment, the reinforcing mesh 15 further comprises a fifth self-expanding arc (not shown in the figure) disposed inside the arc of the third self-expanding 153, the fifth self-expanding arc is composed of two fifth self-expanding arms, the distal ends of the two fifth self-expanding arms are fixedly connected with the two third self-expanding arcs 153 respectively, the proximal ends of the two fifth self-expanding arms are connected, and the width of the fifth self-expanding arm is not larger than the width of the self-expanding arm of the third self-expanding arc.
In one embodiment, referring to fig. 4, the distal end of the self-expanding heart valve stent may comprise a retaining end 16, the retaining end 16 comprising a plurality of retaining end structural units 161 connected to each other, the rods 162 constituting the retaining end structural units 161 having a smaller width at the center and larger widths at the two ends. In the embodiment shown in fig. 4, the rods 162 of the locking end structure unit 161 may be symmetrical, have a minimum width in the middle, and then become larger smoothly toward both ends without abrupt stepwise changes. The edges of the bar 162 are smooth.
In one embodiment, the retaining end structure units 161 are diamond-shaped squares, and the retaining end 16 may include 15 or 18 retaining end structure units 161 arranged in a layer and connected to each other. Adjacent card end structural units 161 may be interconnected by sharing a vertex. The adjacent detent end structure unit 161 connection regions extend a predetermined length in the circumferential and longitudinal directions of the self-expanding heart valve stent, respectively, and include curved structures 163 recessed toward the adjacent detent end structure unit connection regions in the circumferential direction of the self-expanding heart valve stent. Since the width of the ends of the rod 162 is the widest, the rod 162 is the widest near the connection area of the locking end structure unit 161 and is most difficult to deform, so that a large stress is generated during the compression and expansion, which easily causes the rod 162 to break near the connection area of the locking end structure unit 161. By adding the bending structure 163, the bending stress of the rod 62 at the position near the connection area of the catching end structure unit 161 is reduced, and the breakage of the rod 162 can be prevented by the compression and self-expansion process of the catching end of the bracket.
Next, the structure of the connecting member 14 of the present embodiment will be described in more detail. Returning to fig. 1-2, the connecting member 14 may include a connecting block 141, a connecting web 142, and a connecting frame 143. One end of the connecting block 141 forms the proximal end of the heart valve stent, and the other end is connected with the connecting frame 143 through the connecting web 142, and the connecting block 141 is for connecting with a conveyer for conveying the heart valve stent.
Referring to fig. 2, the connecting frame 143 may sequentially include a support connecting portion, a positioning member connecting portion, and a fastener connecting portion in a direction from a proximal end of the heart valve stent to a distal end of the heart valve stent. In one embodiment, the support member connecting portions may be symmetrical and connected to the first support arm of the first support member and the second support arm of the adjacent second support member. In a preferred embodiment, the upper edge of the support arm at the connection to the connecting frame is a smooth arc having an angle of 100 ° to 160 °. Meanwhile, the lower edge of the joint of the supporting arm and the connecting frame is also a smooth arc line, and the angle of the arc line is an acute angle.
In one embodiment, the connecting web has a width less than the width of the connecting piece and less than the width of the connecting portion of the support member. In another embodiment, the connecting frame includes a hollow elongated suture hole 144. The elongated suture holes 144 may be provided at one end thereof at the support connection part and at the other end thereof at the keeper connection part or the fastener connection part. Rectangular shape sews up hole 144 and can realize that artificial heart valve leaflet's near-end edge directly passes the suture hole and sews up, and need not to increase and sew up the gasket, artificial heart valve leaflet's edge is sewed up with the fastening arc, such mode of sewing up, traditional mode of using gasket and support extrusion fixed leaflet relatively, the outer additional spare part of support has at first been reduced, and the gasket has not been had, also be favorable to the further compression of support, if there is the gasket, not only influence the support compression, can damage artificial heart valve leaflet sometimes even under the less condition of support compression support.
In another embodiment, the positioning member may include a pull wire composite ring 124 fixedly connected to the positioning member and located on a side of the positioning member facing the proximal end of the heart valve stent, the pull wire composite ring includes a first through hole 1241 for mounting a marker and a second through hole 1242 adapted to pass a pull wire therethrough, and the second through hole is closer to the proximal end of the heart valve stent than the first through hole. In one embodiment, the first through hole has a larger aperture than the second through hole. The pull wire composite ring structure arranged at the far end of the positioning member 12 combines the installation of the pull wire and the mark 'marker' (the mark is radiopaque) into a position, and effectively reduces the space occupation rate of the product. Utilize a position, can realize opening and shutting control and location of setting element, not only improve the compression performance of product, do benefit to the product and use the pipe to carry, the setting element can open moreover and still do benefit to the degree of difficulty that reduces operation. The stay wire composite ring structure is provided with two through holes, the large hole is used for placing a marker point so as to be conveniently implanted and accurately positioned, the positioning piece is ensured to be in contact with the sinus floor, the small hole is convenient for penetrating the stay wire, in the implantation process, the stay wire is used for controlling the opening angle of the positioning piece, the valve leaflet is convenient to capture, and the operation difficulty is reduced. In a preferred embodiment, the pull-wire composite ring is arranged at the distal end of the positioning part and is inclined inwards relative to the axis of the stent, so that the proximal end of the pull-wire composite ring is prevented from colliding with the wall of an aorta during the shaking of the stent, the aorta is damaged, and the aortic dissection of a user can be seriously caused, and the life of the user can be threatened. So that the positioning piece can be pulled to the outside of the heart valve stent through the pull wire.
In the embodiment shown in the figures, the heart valve stent may comprise 3 structurally identical supports, positioning members, fasteners and connectors. Adjacent connectors are connected by a support member, a positioning member and a fastener. Meanwhile, the adjacent supporting pieces, the positioning pieces and the fastening pieces are connected through the connecting pieces. The heart valve stent is substantially cylindrical when in an expanded state. The artificial heart valve leaflet can be clamped between the supporting member and the positioning member.
Example 2
This example 2 is different from example 1 in that the self-inflating heart valve stent of the present example does not include a support. The present embodiments relate to a self-expanding heart valve stent having a proximal end including a positioning member and a fastener disposed between connecting members, a distal end including a retaining end, and a reinforcing mesh disposed between the fastener and the retaining end. The reinforcing net comprises three self-expansion arcs which are sequentially arranged from the near end to the far end, and the width and the span of the self-expansion arc which is closest to the far end are longest, so that enough radial expansion force can be provided, and the self-expansion heart valve stent can be expanded to be in place.
Referring to fig. 5-7, the self-expanding heart valve stent of the present embodiment is different from the self-expanding heart valve stent of embodiment 1 in that it does not include a support member, and the descriptions of the positioning member, the fastening member, the connecting member, the reinforcing mesh, the locking end, and the self-expanding arc in embodiment 1 are also applicable to the present embodiment, and therefore are not repeated.
It is obvious to a person skilled in the art that the invention is not restricted to details of the above-described exemplary embodiments, but that it can be implemented in other specific forms without departing from the spirit or essential characteristics of the invention. The present embodiments are therefore to be considered in all respects as illustrative and not restrictive, the scope of the invention being indicated by the appended claims rather than by the foregoing description, and all changes which come within the meaning and range of equivalency of the claims are therefore intended to be embraced therein. Any reference sign in a claim should not be construed as limiting the claim concerned.
Claims (15)
1. A self-expanding heart valve stent comprising a distal end of the self-expanding heart valve stent that is proximal to an apex of the heart when the self-expanding heart valve stent is in an expanded state and a proximal end of the self-expanding heart valve stent that is distal to the apex of the heart when the self-expanding heart valve stent is in an expanded state, wherein the proximal end of the self-expanding heart valve stent comprises connectors and fasteners disposed between adjacent connectors, the fasteners being for securing prosthetic heart valve leaflets;
wherein the fastener comprises a first fastening arc, a second fastening arc, and a fastener distal end connecting the first fastening arc and the second fastening arc, the first fastening arc is fixedly connected to a first connector, the second fastening arc is fixedly connected to a second connector, and the first connector is adjacent to the second connector;
wherein the distal end of the self-expanding heart valve stent comprises a clamping end, a reinforcing net is arranged between the clamping end and the fasteners, the distal end of the reinforcing net is fixed to the clamping end, and the proximal end of the reinforcing net is fixedly connected between different fastening arcs of adjacent fasteners;
wherein the reinforcing mesh comprises a first self-expansion arc, a second self-expansion arc and a third self-expansion arc which are arranged in sequence along the direction from the far end of the self-expansion heart valve support to the near end of the self-expansion heart valve support, one end of the first self-expansion arc is fixedly connected with the first fastening arc of the fastening piece, the other end of the first self-expansion arc is fixedly connected with the second fastening arc of the adjacent fastening piece, and the first self-expansion arc, the second self-expansion arc and the third self-expansion arc are protruded towards the far end of the heart valve support; two ends of the second self-expansion arc are respectively fixedly connected to the first self-expansion arc and protrude towards the proximal end of the heart valve stent; one end of the third self-expanding arc is fixedly connected with the first fastening arc of the fastener, the other end of the third self-expanding arc is fixedly connected with the second fastening arc of the adjacent fastener and protrudes towards the far end of the heart valve stent, and a gap is formed between the second self-expanding arc and the third self-expanding arc.
2. The self-inflating heart valve stent of claim 1, wherein the width of the first self-inflating arcs is greater than the width of the second self-inflating arcs and the width of the third self-inflating arcs.
3. The self-expanding heart valve stent of claim 1, wherein the span of the first self-expanding arc is greater than the span of the second self-expanding arc and the span of the third self-expanding arc.
4. The self-expanding heart valve stent of any one of claims 1-3, wherein the first self-expanding arcs are formed by two first self-expanding arms, proximal ends of the two first self-expanding arms are fixedly connected with middle positions of the two fastening arcs respectively, distal ends of the two first self-expanding arms are connected with each other, and the connecting positions of the distal ends of the two first self-expanding arms and the clamping ends are also fixedly connected;
the second self-expansion arc is composed of two second self-expansion arms, the far ends of the two second self-expansion arms are respectively fixedly connected with the middle positions of the two first self-expansion arms, and the near ends of the two second self-expansion arms are connected;
the third self-expansion arc is composed of two third self-expansion arms, the near ends of the two third self-expansion arms are fixedly connected with the positions, close to the near ends, of the two fastening arcs respectively, and the far ends of the two third self-expansion arms are connected.
5. The self-expanding heart valve stent of claim 4, wherein the proximal ends of the two third self-expanding arms are fixedly connected to 1/4 of the proximal ends of the two fastening arcs, respectively.
6. The self-inflating heart valve stent of claim 5, wherein the second self-inflating arm has a length that is half the length of the first self-inflating arm, and the third self-inflating arm has a length that is half the length of the second self-inflating arm.
7. The self-expanding heart valve stent of claim 5, wherein when the self-expanding heart valve stent is in an expanded state, first fastening arcs of a fastener form first rounded corners with second fastening arcs of adjacent fasteners, the first self-expanding arcs have second rounded corners, and the third self-expanding arcs have third rounded corners;
wherein, the third fillet is not more than the first fillet that its adjacent fastening arc that corresponds formed, and the second fillet is greater than first fillet and third fillet.
8. The self-expanding heart valve stent of claim 4, wherein the reinforcing mesh further comprises additional self-expanding arcs disposed inside the second self-expanding arcs or inside the third self-expanding arcs, and a sum of the number of self-expanding arcs of the reinforcing mesh is less than or equal to 5.
9. The self-expanding heart valve stent of claim 8, wherein the reinforcing mesh further comprises a fourth self-expanding arc disposed inside the second self-expanding arc, the fourth self-expanding arc comprised of two fourth self-expanding arms, distal ends of the two fourth self-expanding arms fixedly connected to the two first self-expanding arms, respectively, and proximal ends of the two fourth self-expanding arms connected to each other;
the width of the fourth self-expanding arm is smaller than the width of the self-expanding arm of the first self-expanding arc and not greater than the width of the self-expanding arm of the second self-expanding arc.
10. The self-expanding heart valve stent of claim 8, wherein the reinforcing mesh further comprises a fourth self-expanding arc disposed inside the second self-expanding arc, the fourth self-expanding arc being formed by two fourth self-expanding arms, proximal ends of the two fourth self-expanding arms being fixedly connected to the two second self-expanding arms, respectively, and distal ends of the two fourth self-expanding arms being connected;
the width of the fourth self-expanding arm is smaller than the width of the self-expanding arm of the first self-expanding arc and not greater than the width of the self-expanding arm of the second self-expanding arc.
11. The self-expanding heart valve stent of claim 9 or 10, wherein a fourth arc of self-expansion has a fourth rounded corner when the self-expanding heart valve stent is in the expanded state, the fourth rounded corner being no greater than a proximal rounded corner formed by the second arc of self-expansion.
12. The self-expanding heart valve stent of claim 8, wherein the reinforcing mesh further comprises a fifth self-expanding arc disposed inside the third self-expanding arc, the fifth self-expanding arc being formed by two fifth self-expanding arms, proximal ends of the two fifth self-expanding arms being fixedly connected to the two fastening arcs at positions near the proximal ends, respectively, and distal ends of the two fifth self-expanding arms being connected;
the width of the fifth self-expanding arm is not greater than the width of the self-expanding arm of the third self-expanding arc.
13. The self-expanding heart valve stent of claim 8, wherein the reinforcing mesh further comprises fifth self-expanding arcs disposed inside the third self-expanding arcs, the fifth self-expanding arcs being formed of two fifth self-expanding arms, distal ends of the two fifth self-expanding arms being fixedly connected to the two third self-expanding arcs, respectively, and proximal ends of the two fifth self-expanding arms being connected to each other;
the width of the fifth self-expanding arm is not greater than the width of the self-expanding arm of the third self-expanding arc.
14. The self-expanding heart valve stent of claim 12 or 13, wherein a third self-expanding arc has a third rounded corner and a fifth self-expanding arc has a fifth rounded corner when the self-expanding heart valve stent is in an expanded state, the fifth rounded corner being no larger than the third rounded corner.
15. The self-expanding heart valve stent of claim 4, further comprising a support member and a positioning member disposed between adjacent connectors, the support member including a first support arm fixedly connected to a first connector, a second support arm fixedly connected to a second connector, and a support member distal end connecting the first support arm and the second support arm, the first connector being adjacent to the second connector;
the positioning part comprises a first positioning arm, a second positioning arm and a positioning part far end for connecting the first positioning arm and the second positioning arm, the first positioning arm is fixedly connected to a first connecting piece, the second positioning arm is fixedly connected to a second connecting piece, and the first connecting piece is adjacent to the second connecting piece;
the setting element is than the support is closer to from expanding heart valve support distal end, the fastener is closer than the setting element is from expanding heart valve support distal end, the support distal end with the setting element distal end is for facing from the bellied pole of expanding heart valve support distal end, the support sets up the one side at native heart valve leaf, just the setting element sets up the opposite side at native heart valve leaf.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2022103159315 | 2022-03-28 | ||
| CN202210315931 | 2022-03-28 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN218356471U true CN218356471U (en) | 2023-01-24 |
Family
ID=83327508
Family Applications (22)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202221105879.2U Active CN218356472U (en) | 2022-03-28 | 2022-05-09 | Anti-regurgitation heart valve stent easy to clamp valve leaflets |
| CN202221101729.4U Active CN218356470U (en) | 2022-03-28 | 2022-05-09 | Lightweight heart valve stent |
| CN202210501497.XA Pending CN116849870A (en) | 2022-03-28 | 2022-05-09 | heart valve stent |
| CN202210503196.0A Pending CN116849871A (en) | 2022-03-28 | 2022-05-09 | Anti-reflux heart valve stent easy to clamp valve leaflets |
| CN202210501495.0A Pending CN116849869A (en) | 2022-03-28 | 2022-05-09 | self-expanding heart valve stent |
| CN202221105878.8U Active CN218356471U (en) | 2022-03-28 | 2022-05-09 | Self-expanding heart valve stent |
| CN202210658355.4A Pending CN115381598A (en) | 2022-03-28 | 2022-06-10 | Self-expanding heart valve stent comprising a cover |
| CN202221451655.7U Active CN218792636U (en) | 2022-03-28 | 2022-06-10 | Stay wire composite ring and self-expansion heart valve stent comprising same |
| CN202210657572.1A Pending CN115381597A (en) | 2022-03-28 | 2022-06-10 | Stay wire composite ring and self-expansion heart valve stent comprising same |
| CN202221451662.7U Active CN218792637U (en) | 2022-03-28 | 2022-06-10 | Self-expanding heart valve stent comprising a cover |
| CN202221504689.8U Active CN219000725U (en) | 2022-03-28 | 2022-06-15 | Reinforcing mesh for self-expanding heart valve stent |
| CN202210682246.6A Active CN115105259B (en) | 2022-03-28 | 2022-06-15 | Self-expanding heart valve stent including a curved self-expanding arc |
| CN202222390126.7U Active CN219000720U (en) | 2022-03-28 | 2022-09-08 | Reinforcing mesh for aortic regurgitation stent for facilitating compression |
| CN202222390698.5U Active CN219332099U (en) | 2022-03-28 | 2022-09-08 | Proximal structure for a retrievable aortic regurgitation stent |
| CN202211098045.8A Pending CN116807684A (en) | 2022-03-28 | 2022-09-08 | Recoverable aortic regurgitation support |
| CN202211176308.2A Pending CN116807685A (en) | 2022-03-28 | 2022-09-26 | Delivery instrument for heart valve |
| CN202310838434.8A Pending CN116869705A (en) | 2022-03-28 | 2022-11-08 | Aortic regurgitation support with positioning piece flexible |
| CN202211391770.4A Active CN115670750B (en) | 2022-03-28 | 2022-11-08 | Easy-to-control aortic regurgitation stent |
| CN202211391341.7A Active CN115624416B (en) | 2022-03-28 | 2022-11-08 | Aortic regurgitation support with positioning piece flexible |
| CN202310305582.3A Pending CN116807686A (en) | 2022-03-28 | 2023-03-27 | Reverse flow support for preventing peripheral leakage |
| CN202311242719.1A Pending CN117752468A (en) | 2022-03-28 | 2023-09-25 | Precise bending-adjusting reverse flow heart valve conveyor and conveying system |
| CN202311242718.7A Pending CN117752467A (en) | 2022-03-28 | 2023-09-25 | Precise-positioning regurgitation heart valve conveyor and conveying system |
Family Applications Before (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202221105879.2U Active CN218356472U (en) | 2022-03-28 | 2022-05-09 | Anti-regurgitation heart valve stent easy to clamp valve leaflets |
| CN202221101729.4U Active CN218356470U (en) | 2022-03-28 | 2022-05-09 | Lightweight heart valve stent |
| CN202210501497.XA Pending CN116849870A (en) | 2022-03-28 | 2022-05-09 | heart valve stent |
| CN202210503196.0A Pending CN116849871A (en) | 2022-03-28 | 2022-05-09 | Anti-reflux heart valve stent easy to clamp valve leaflets |
| CN202210501495.0A Pending CN116849869A (en) | 2022-03-28 | 2022-05-09 | self-expanding heart valve stent |
Family Applications After (16)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202210658355.4A Pending CN115381598A (en) | 2022-03-28 | 2022-06-10 | Self-expanding heart valve stent comprising a cover |
| CN202221451655.7U Active CN218792636U (en) | 2022-03-28 | 2022-06-10 | Stay wire composite ring and self-expansion heart valve stent comprising same |
| CN202210657572.1A Pending CN115381597A (en) | 2022-03-28 | 2022-06-10 | Stay wire composite ring and self-expansion heart valve stent comprising same |
| CN202221451662.7U Active CN218792637U (en) | 2022-03-28 | 2022-06-10 | Self-expanding heart valve stent comprising a cover |
| CN202221504689.8U Active CN219000725U (en) | 2022-03-28 | 2022-06-15 | Reinforcing mesh for self-expanding heart valve stent |
| CN202210682246.6A Active CN115105259B (en) | 2022-03-28 | 2022-06-15 | Self-expanding heart valve stent including a curved self-expanding arc |
| CN202222390126.7U Active CN219000720U (en) | 2022-03-28 | 2022-09-08 | Reinforcing mesh for aortic regurgitation stent for facilitating compression |
| CN202222390698.5U Active CN219332099U (en) | 2022-03-28 | 2022-09-08 | Proximal structure for a retrievable aortic regurgitation stent |
| CN202211098045.8A Pending CN116807684A (en) | 2022-03-28 | 2022-09-08 | Recoverable aortic regurgitation support |
| CN202211176308.2A Pending CN116807685A (en) | 2022-03-28 | 2022-09-26 | Delivery instrument for heart valve |
| CN202310838434.8A Pending CN116869705A (en) | 2022-03-28 | 2022-11-08 | Aortic regurgitation support with positioning piece flexible |
| CN202211391770.4A Active CN115670750B (en) | 2022-03-28 | 2022-11-08 | Easy-to-control aortic regurgitation stent |
| CN202211391341.7A Active CN115624416B (en) | 2022-03-28 | 2022-11-08 | Aortic regurgitation support with positioning piece flexible |
| CN202310305582.3A Pending CN116807686A (en) | 2022-03-28 | 2023-03-27 | Reverse flow support for preventing peripheral leakage |
| CN202311242719.1A Pending CN117752468A (en) | 2022-03-28 | 2023-09-25 | Precise bending-adjusting reverse flow heart valve conveyor and conveying system |
| CN202311242718.7A Pending CN117752467A (en) | 2022-03-28 | 2023-09-25 | Precise-positioning regurgitation heart valve conveyor and conveying system |
Country Status (2)
| Country | Link |
|---|---|
| CN (22) | CN218356472U (en) |
| WO (1) | WO2023184639A1 (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2023185169A1 (en) * | 2022-03-28 | 2023-10-05 | 科凯(南通)生命科学有限公司 | Prosthetic valve |
| CN115944356A (en) * | 2023-02-10 | 2023-04-11 | 上海珩畅医疗科技有限公司 | Bracket component for removing thrombus |
| CN116919683B (en) * | 2023-09-15 | 2023-12-08 | 北京华脉泰科医疗器械股份有限公司 | Branched endovascular prosthesis and endovascular prosthesis delivery device |
Family Cites Families (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8834564B2 (en) * | 2006-09-19 | 2014-09-16 | Medtronic, Inc. | Sinus-engaging valve fixation member |
| US8876894B2 (en) * | 2006-09-19 | 2014-11-04 | Medtronic Ventor Technologies Ltd. | Leaflet-sensitive valve fixation member |
| ES2488119T3 (en) * | 2008-02-26 | 2014-08-26 | Jenavalve Technology Gmbh | Stent for placement and anchoring of a valvular prosthesis at an implantation site in the heart of a patient |
| EP3181096A1 (en) * | 2009-02-25 | 2017-06-21 | JenaValve Technology, Inc. | Stent for the positioning and anchoring of a valvular prosthesis in an implantation site in the heart of a patient |
| CA2752660A1 (en) * | 2010-02-25 | 2010-08-05 | Jenavalve Technology Inc. | Stent for the positioning and anchoring of a valvular prosthesis in an implantation site in the heart of a patient |
| US9744031B2 (en) * | 2010-05-25 | 2017-08-29 | Jenavalve Technology, Inc. | Prosthetic heart valve and endoprosthesis comprising a prosthetic heart valve and a stent |
| WO2014203106A1 (en) * | 2013-06-21 | 2014-12-24 | Jenavalve Technology Gmbh | Collapsible prosthetic heart valve |
| JP6563394B2 (en) * | 2013-08-30 | 2019-08-21 | イェーナヴァルヴ テクノロジー インコーポレイテッド | Radially foldable frame for an artificial valve and method for manufacturing the frame |
| WO2015173794A1 (en) * | 2014-05-16 | 2015-11-19 | Benichou, Netanel | Replacement heart valve |
| CN107530166B (en) * | 2015-02-13 | 2020-01-31 | 魅尔皮德股份有限公司 | Valve replacement using a rotating anchor |
| CN104799974A (en) * | 2015-04-20 | 2015-07-29 | 上海纽脉医疗科技有限公司 | Involvement type prosthetic heart valve stent with barbs and preparation method thereof |
| US10357361B2 (en) * | 2016-09-15 | 2019-07-23 | Edwards Lifesciences Corporation | Heart valve pinch devices and delivery systems |
| CA3101165A1 (en) * | 2018-05-23 | 2019-11-28 | Sorin Group Italia S.R.L. | A cardiac valve prosthesis |
| CA3116158A1 (en) * | 2018-11-01 | 2020-05-07 | Edwards Lifesciences Corporation | Transcatheter pulmonic regenerative valve |
| CN109350310B (en) * | 2018-12-14 | 2021-07-02 | 宁波健世科技股份有限公司 | Valve stent capable of avoiding coronary artery blockage |
| CN210301317U (en) * | 2019-04-28 | 2020-04-14 | 中国人民解放军陆军军医大学第一附属医院 | Stent with anti-regurgitation valve |
| EP4175589A1 (en) * | 2020-07-01 | 2023-05-10 | Invalve Therapeutics, Inc. | Heart valve prostheses and related methods |
| CN113440308A (en) * | 2020-07-17 | 2021-09-28 | 宁波健世生物科技有限公司 | Valve prosthesis with variable positioning part and conveying system thereof |
| CN113413239A (en) * | 2020-07-17 | 2021-09-21 | 宁波健世科技股份有限公司 | Valve prosthesis with positioning piece and conveying system thereof |
| CN114176833A (en) * | 2020-09-15 | 2022-03-15 | 杭州德晋医疗科技有限公司 | Artificial heart valve support and artificial heart valve |
| US11197755B1 (en) * | 2020-10-28 | 2021-12-14 | Occam Labs LLC | Systems, devices and methods for folded unibody heart valve stents |
| CN112891027A (en) * | 2021-01-26 | 2021-06-04 | 复旦大学附属中山医院 | Novel transcatheter artificial aortic valve system for transarterial approach |
| CN113288519A (en) * | 2021-07-01 | 2021-08-24 | 武汉唯柯医疗科技有限公司 | Transcatheter aortic valve device capable of actively capturing valve leaflets |
| CN113679512A (en) * | 2021-08-11 | 2021-11-23 | 上海傲流医疗科技有限公司 | Repair device for treating tricuspid valve regurgitation |
| CN113893066A (en) * | 2021-11-02 | 2022-01-07 | 环心医疗科技(苏州)有限公司 | Anti-backflow artificial heart valve |
| CN114099075A (en) * | 2021-11-16 | 2022-03-01 | 上海傲流医疗科技有限公司 | Valve backflow repair clamp control structure |
-
2022
- 2022-04-28 WO PCT/CN2022/089819 patent/WO2023184639A1/en unknown
- 2022-05-09 CN CN202221105879.2U patent/CN218356472U/en active Active
- 2022-05-09 CN CN202221101729.4U patent/CN218356470U/en active Active
- 2022-05-09 CN CN202210501497.XA patent/CN116849870A/en active Pending
- 2022-05-09 CN CN202210503196.0A patent/CN116849871A/en active Pending
- 2022-05-09 CN CN202210501495.0A patent/CN116849869A/en active Pending
- 2022-05-09 CN CN202221105878.8U patent/CN218356471U/en active Active
- 2022-06-10 CN CN202210658355.4A patent/CN115381598A/en active Pending
- 2022-06-10 CN CN202221451655.7U patent/CN218792636U/en active Active
- 2022-06-10 CN CN202210657572.1A patent/CN115381597A/en active Pending
- 2022-06-10 CN CN202221451662.7U patent/CN218792637U/en active Active
- 2022-06-15 CN CN202221504689.8U patent/CN219000725U/en active Active
- 2022-06-15 CN CN202210682246.6A patent/CN115105259B/en active Active
- 2022-09-08 CN CN202222390126.7U patent/CN219000720U/en active Active
- 2022-09-08 CN CN202222390698.5U patent/CN219332099U/en active Active
- 2022-09-08 CN CN202211098045.8A patent/CN116807684A/en active Pending
- 2022-09-26 CN CN202211176308.2A patent/CN116807685A/en active Pending
- 2022-11-08 CN CN202310838434.8A patent/CN116869705A/en active Pending
- 2022-11-08 CN CN202211391770.4A patent/CN115670750B/en active Active
- 2022-11-08 CN CN202211391341.7A patent/CN115624416B/en active Active
-
2023
- 2023-03-27 CN CN202310305582.3A patent/CN116807686A/en active Pending
- 2023-09-25 CN CN202311242719.1A patent/CN117752468A/en active Pending
- 2023-09-25 CN CN202311242718.7A patent/CN117752467A/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CN115105259B (en) | 2023-04-28 |
| CN116869705A (en) | 2023-10-13 |
| CN115381598A (en) | 2022-11-25 |
| CN219000720U (en) | 2023-05-12 |
| CN219000725U (en) | 2023-05-12 |
| CN115624416B (en) | 2023-08-11 |
| CN116807685A (en) | 2023-09-29 |
| CN116807684A (en) | 2023-09-29 |
| WO2023184639A1 (en) | 2023-10-05 |
| CN117752468A (en) | 2024-03-26 |
| CN218792636U (en) | 2023-04-07 |
| CN116807686A (en) | 2023-09-29 |
| CN115381597A (en) | 2022-11-25 |
| CN117752467A (en) | 2024-03-26 |
| CN115624416A (en) | 2023-01-20 |
| CN116849871A (en) | 2023-10-10 |
| CN218356472U (en) | 2023-01-24 |
| CN218356470U (en) | 2023-01-24 |
| CN115105259A (en) | 2022-09-27 |
| CN219332099U (en) | 2023-07-14 |
| CN218792637U (en) | 2023-04-07 |
| CN115670750B (en) | 2023-11-17 |
| CN115670750A (en) | 2023-02-03 |
| CN116849869A (en) | 2023-10-10 |
| CN116849870A (en) | 2023-10-10 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN218356471U (en) | Self-expanding heart valve stent | |
| US11395734B2 (en) | Prosthetic valve and prosthetic valve implanting method | |
| CN111050701A (en) | Sealing member for prosthetic heart valve | |
| CN215458984U (en) | Valve stent and prosthetic valve assembly | |
| CN113893068A (en) | Repair device for treating tricuspid valve regurgitation | |
| CN116269942B (en) | Artificial heart valve | |
| CN115177405A (en) | High-elasticity anti-reflux heart valve stent | |
| US20240122701A1 (en) | Devices, Systems, and Methods for a Valve Replacement | |
| CN210872250U (en) | Valve support and have its artificial valve | |
| CN113855324A (en) | Valve support reaches intervention mitral valve replacement system including it | |
| CN218792642U (en) | Reinforcing mesh for high-elasticity anti-reflux heart valve stent | |
| CN113855323A (en) | Interventional mitral valve and interventional mitral valve replacement system comprising same | |
| CN219332106U (en) | Anti-regurgitation stent and prosthetic valve device suitable for annuloplasty | |
| CN219332105U (en) | High stability anti-reflux stent and prosthetic valve device | |
| CN218792640U (en) | Anti-regurgitation stent and artificial valve device convenient to retrieve | |
| WO2023185169A1 (en) | Prosthetic valve | |
| CN217138358U (en) | Trans-apical mitral valve stent | |
| CN217853486U (en) | Self-expanding heart valve repair stent | |
| CN219332104U (en) | Anti-reflux stent and prosthetic valve device convenient to position | |
| CN217448134U (en) | Short-configuration mitral valve stent | |
| CN217286187U (en) | Valve stent and valve prosthesis | |
| CN117338482A (en) | Anti-regurgitation stent and prosthetic valve device facilitating radial contraction | |
| CN117338480A (en) | Stable anti-reflux stent and prosthetic valve device | |
| CN117481870A (en) | Valve stent and prosthetic valve | |
| CN115517821A (en) | Transapical mitral valve replacement device |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant |