CN218131738U

CN218131738U - Ticagrelor raw medicine synthesis reaction kettle

Info

Publication number: CN218131738U
Application number: CN202222219069.6U
Authority: CN
Inventors: 任纪纯; 乔亚文
Original assignee: Xinxiang Kexin Chemical Co ltd
Current assignee: Xinxiang Kexin Chemical Co ltd
Priority date: 2022-08-23
Filing date: 2022-08-23
Publication date: 2022-12-27
Anticipated expiration: 2032-08-23

Abstract

The utility model discloses a ticagrelor bulk drug synthesis reation kettle relates to synthetic reation kettle technical field, including the reation kettle body, the top cap is installed at the top of reation kettle body, and the top of top cap is connected with crushing box, the lantern ring is installed at the top of crushing box, and the top of the lantern ring is connected with a feeding section of thick bamboo, peg graft in the inboard bottom of a feeding section of thick bamboo and have solid fixed ring, and solid fixed ring's both ends all connect the dead lever, solid fixed ring's internally mounted has two-way motor. The utility model discloses in, be provided with a feeding section of thick bamboo, smash box, two-way motor, axostylus axostyle, crushed aggregates blade and filter plate, drive the crushed aggregates blade on the axostylus axostyle through two-way motor, carry out crushing work to raw materials and auxiliary material, then, in screening into reation kettle with up to standard compounding through the filter plate for the synthesis of ticagrelor bulk drug reacts effectually, and, can prevent that solid compounding from blockking up on the mesh of filter plate, influences the unloading work of subsequent ticagrelor raw materials and auxiliary material.

Description

Ticagrelor raw medicine synthesis reaction kettle

Technical Field

The utility model relates to a synthetic reation kettle technical field especially relates to a ticagrelor raw material medicine synthetic reation kettle.

Background

Ticagrelor is a platelet aggregation inhibitor, the trade name of the Ticagrelor is Beilingda, round, biconvex and yellow coated tablets, one side is carved with 'T', the upper side is carved with '90' characters, the other side is smooth, and the Ticagrelor contains 90mg, and the synthesis of the Ticagrelor raw material medicines at present needs to use a reaction kettle.

In chinese utility model patent application publication No. cn202122625312.X discloses a synthesis reation kettle for ticagrelor raw material medicine, this ticagrelor transport material medicine synthesis reation kettle has solved in production process, the inhomogeneous problem of material mixing, however, this ticagrelor raw materials's solid starting material is at the unloading in-process, too big solid caking, and the mesh of stopping up feed cylinder bottom easily influences the job schedule of subsequent fixed raw materials unloading.

SUMMERY OF THE UTILITY MODEL

The utility model aims at solving the solid raw materials of current ticagrelor raw materials at the unloading in-process, too big solid caking, the mesh of feed cylinder bottom is lived to the easy jam, influences the shortcoming of the job schedule of subsequent fixed raw materials unloading, and the synthetic reation kettle of ticagrelor bulk drug that provides.

In order to realize the purpose, the utility model adopts the following technical scheme:

a ticagrelor raw material medicine synthesis reaction kettle comprises:

the reaction kettle comprises a reaction kettle body, wherein a top cover is installed at the top of the reaction kettle body, a crushing box is connected to the top of the top cover, a lantern ring is installed at the top of the crushing box, a feeding cylinder is connected to the top of the lantern ring, a fixing ring is inserted into the bottom of the inner side of the feeding cylinder, two ends of the fixing ring are connected with fixing rods, a two-way motor is installed inside the fixing ring, the output end of the top of the two-way motor is connected with a connecting rod, and an umbrella-shaped top plate is installed at the top of the connecting rod;

the axostylus axostyle, the axostylus axostyle is installed at two-way motor's bottom output, and the external connection of axostylus axostyle has crushed aggregates blade, the bottom of axostylus axostyle is provided with rotatory piece, and the outside of rotatory piece has cup jointed the filter plate, the spout has been seted up to the inside of smashing the box, and the inside of spout inlays and have the slider, the one end of slider is connected with the outer wall of filter plate.

Preferably, the feeding cylinder forms a detachable structure with the lantern ring and the crushing box through bolts, and the lantern ring is communicated with the feeding cylinder and the crushing box.

Preferably, the umbrella-shaped top plate forms a rotating structure with the fixing ring through the connecting rod, the bidirectional motor and the fixing ring, and the diameter of the umbrella-shaped top plate is larger than the outer diameter of the fixing ring.

Preferably, the crushing blades are fixedly connected with the shaft rod, and two groups of crushing blades are arranged.

Preferably, the filter plate and the crushing box form a movable structure through a sliding block and a sliding groove, and the sliding block is in sliding connection with the sliding groove.

Preferably, the cross section of the fixing rod is of a triangular structure, and the fixing rod is fixedly connected with the fixing ring.

To sum up, owing to adopted above-mentioned technical scheme, the beneficial effects of the utility model are that:

1. the utility model discloses in, be provided with a feeding section of thick bamboo, smash box, two-way motor, axostylus axostyle, crushed aggregates blade and filter plate, drive the crushed aggregates blade on the axostylus axostyle through two-way motor, carry out broken work to raw materials and auxiliary material, then, in screening reation kettle through the filter plate with up to standard mixture for the synthesis of the crude drug of Tiger Ruiluo reacts effectually, and, can prevent that solid compounding from blockking up on the mesh of filter plate, influence the unloading work of subsequent Tiger Ruiluo raw materials and auxiliary material.

2. The utility model discloses in, be provided with the effect of a feeding section of thick bamboo, the lantern ring and smash the box, conveniently unscrew the bolt between a feeding section of thick bamboo and the lantern ring, dismantle a feeding section of thick bamboo and crushing box, the part of convenience in to a feeding section of thick bamboo carries out maintenance work, simultaneously, conveniently changes work to the filter plate in smashing the box.

Drawings

FIG. 1 is a schematic view of the overall structure of the present invention;

FIG. 2 is a schematic view of the internal structure of the connection between the crushing box and the feeding cylinder;

fig. 3 is a schematic view of the top-view internal structure of the middle feeding cylinder of the present invention.

Illustration of the drawings:

1. a reaction kettle body; 2. a top cover; 3. a feeding cylinder; 4. a crushing box; 5. a fixing ring; 6. a bi-directional motor; 7. an umbrella-shaped top plate; 8. a connecting rod; 9. a collar; 10. a shaft lever; 11. a crushing blade; 12. a chute; 13. a slider; 14. filtering the plate; 15. rotating the block; 16. and (6) fixing the rod.

Detailed Description

The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by a person skilled in the art without making creative efforts belong to the protection scope of the present invention.

Referring to fig. 1-3, a ticagrelor bulk drug synthesis reaction kettle, including a reaction kettle body 1, a top cover 2 is installed on the top of the reaction kettle body 1, and the top of the top cover 2 is connected with a crushing box 4, a lantern ring 9 is installed on the top of the crushing box 4, and the top of the lantern ring 9 is connected with a feeding cylinder 3, the feeding cylinder 3 forms a detachable structure with the lantern ring 9 through bolts, the crushing box 4 forms a communication state with the feeding cylinder 3, ticagrelor bulk drug and adjuvant are proportioned through the feeding cylinder 3, input into the reaction kettle body 1, carry out mixed reaction work, and through unscrewing the feeding cylinder 3 and the lantern ring 9, the bolts between the crushing boxes 4, facilitate maintenance work on the parts inside the feeding cylinder 3, a fixing ring 5 is inserted at the bottom of the inner side of the feeding cylinder 3, and both ends of the fixing ring 5 are connected with fixing rods 16, the cross-section of the fixing rods 16 is of a triangular structure, and the

fixing rods

16 and 5 are fixedly connected, so that the top of the fixing rods 16 does not take over the ticagrelor bulk drug and adjuvant, the top plate 7 are connected with a top plate 6, and the top plate 7 of a motor 7, thereby the connecting rod 7 is connected with the top plate 6, the top plate 7 of the umbrella-top plate 6, the umbrella-type bulk drug synthesis reaction kettle can not take over the bidirectional motor 7, and the bidirectional motor 7, affecting the use of the bi-directional motor 6;

the axostylus axostyle 10, axostylus axostyle 10 is installed at the bottom output of two-way motor 6, and the external connection of axostylus axostyle 10 has crushed aggregates blade 11, be fixed connection between crushed aggregates blade 11 and the axostylus axostyle 10, and crushed aggregates blade 11 is provided with two sets ofly, it drives crushed aggregates blade 11 to drive axostylus axostyle 10 through two-way motor 6, solid raw materials and the auxiliary material of stopping on filter plate 14 to the whereabouts carry out crushing work, it is good to improve the mixed reaction effect of ticagrelor raw materials and auxiliary material, the bottom of axostylus axostyle 10 is provided with rotatory piece 15, and filter plate 14 has been cup jointed to the outside of rotatory piece 15, filter plate 14 passes through slider 13, spout 12 constitutes movable structure with crushing box 4, and be sliding connection between slider 13 and spout 12, through the effect of filter plate 14, sieve broken ticagrelor raw materials and auxiliary material mixed sieve in the reation kettle, improve the efficiency of ticagrelor raw materials synthetic reaction, spout 12 has been seted up to the inside of crushing box 4, and the inside is inlayed and has slider 13, the one end of slider is connected with the outer wall of filter plate 14.

The working principle is as follows: during the use, at first, the ticagrelor raw materials and auxiliary materials which are proportioned are input into the feeding cylinder 3 of the top cover 2 of the reaction kettle body 1 through an operator, then the two-way motor 6 is started, the connecting rod 8 and the umbrella-shaped top plate 7 at the upper end of the two-way motor 6 are made to rotate, the ticagrelor raw materials and auxiliary materials which fall in the feeding cylinder 3 are mixed and dispersed, the ticagrelor raw materials and auxiliary materials are prevented from entering the fixing ring 5, the use of the two-way motor 6 is influenced, the dispersed mixed materials enter the area of the shaft rod 10 and the crushed material blade 11, the crushing work is carried out, the crushed mixed materials are screened into the reaction kettle body 1 through the filter plate 14, and finally, the maintenance work of parts in the feeding cylinder 3 is facilitated through bolts among the feeding cylinder 3, the sleeve ring 9 and the crushing box 4.

The above, only be the embodiment of the preferred of the present invention, but the protection scope of the present invention is not limited thereto, and any person skilled in the art is in the technical scope of the present invention, according to the technical solution of the present invention and the utility model, which are designed to be replaced or changed equally, all should be covered within the protection scope of the present invention.

Claims

1. A ticagrelor raw material medicine synthesis reaction kettle is characterized by comprising:

the reaction kettle comprises a reaction kettle body (1), wherein a top cover (2) is installed at the top of the reaction kettle body (1), a crushing box (4) is connected to the top of the top cover (2), a lantern ring (9) is installed at the top of the crushing box (4), a feeding cylinder (3) is connected to the top of the lantern ring (9), a fixing ring (5) is inserted into the bottom of the inner side of the feeding cylinder (3), two ends of the fixing ring (5) are connected with fixing rods (16), a bidirectional motor (6) is installed inside the fixing ring (5), the output end of the top of the bidirectional motor (6) is connected with a connecting rod (8), and an umbrella-shaped top plate (7) is installed at the top of the connecting rod (8);

axostylus axostyle (10), the bottom output at two-way motor (6) is installed in axostylus axostyle (10), and the external connection of axostylus axostyle (10) has crushed aggregates blade (11), the bottom of axostylus axostyle (10) is provided with rotatory piece (15), and the outside of rotatory piece (15) has cup jointed filter plate (14), spout (12) have been seted up to the inside of smashing box (4), and the inside of spout (12) is inlayed and is had slider (13), the one end of slider (13) is connected with the outer wall of filter plate (14).

2. The ticagrelor crude drug synthesis reaction kettle according to claim 1, characterized in that: the feeding cylinder (3) forms a detachable structure with the lantern ring (9) and the crushing box (4) through bolts, and the lantern ring (9) is communicated with the feeding cylinder (3) and the crushing box (4).

3. The ticagrelor raw material medicine synthesis reaction kettle according to claim 1, characterized in that: the umbrella-shaped top plate (7) forms a rotating structure with the fixing ring (5) through the connecting rod (8), the two-way motor (6), and the diameter of the umbrella-shaped top plate (7) is larger than the outer diameter of the fixing ring (5).

4. The ticagrelor crude drug synthesis reaction kettle according to claim 1, characterized in that: the material crushing blades (11) are fixedly connected with the shaft lever (10), and two groups of material crushing blades (11) are arranged.

5. The ticagrelor raw material medicine synthesis reaction kettle according to claim 1, characterized in that: the filter plate (14) and the crushing box (4) form a movable structure through a sliding block (13), a sliding groove (12), and the sliding block (13) is in sliding connection with the sliding groove (12).

6. The ticagrelor crude drug synthesis reaction kettle according to claim 1, characterized in that: the cross section of the fixing rod (16) is of a triangular structure, and the fixing rod (16) is fixedly connected with the fixing ring (5).