CN217787122U

CN217787122U - Chemiluminescence immune analyzer capable of adding liquid and detecting instantly

Info

Publication number: CN217787122U
Application number: CN202221417164.0U
Authority: CN
Inventors: 魏红帅; 吴亚楠; 张小芳
Original assignee: Haiyin Biotechnology Beijing Co ltd
Current assignee: Haiyin Biotechnology Beijing Co ltd
Priority date: 2022-06-08
Filing date: 2022-06-08
Publication date: 2022-11-11
Anticipated expiration: 2032-06-08

Abstract

The utility model discloses a chemiluminescence immunoassay appearance, chemiluminescence immunoassay appearance includes shell and analyzer body, and the analyzer body includes: reaction cup, reaction cup support, reaction cup moving mechanism, liquid feeding needle, photomultiplier. The utility model is suitable for a same treat the immunoreaction that the sample needs add multiple reagent to go on according to the precedence, can carry out the luminous detection and the analysis of reactant immediately, improved the efficiency of detection and analysis.

Description

Chemiluminescence immune analyzer capable of adding liquid and detecting instantly

Technical Field

The utility model belongs to the technical field of external diagnostic equipment, concretely relates to chemiluminescence immunoassay appearance of instant liquid feeding and detection.

Background

The chemiluminescence analyzer has the advantages of high sensitivity, high automation degree, high sample processing speed and the like, and becomes a main means of immunoassay diagnosis. However, the large-scale full-automatic chemiluminescence immune analyzer has high manufacturing cost, large volume and complex structure.

With the development of technology, the advent of some small chemiluminescent immunoassays has made up for the shortcomings of large analyzers. For example, chinese patent CN216051761U discloses a full-automatic chemiluminescence immune analyzer, but, there is only one sample adding needle in the miniaturized analyzer, and the same sample adding needle is used to absorb sample and reagent, and it needs to be cleaned after each sample adding. The analyzer is not suitable for chemiluminescence immune reaction of immediately carrying out luminescence reaction detection after the same sample to be detected and two or more reagents are continuously added according to the sequence.

SUMMERY OF THE UTILITY MODEL

In order to adapt to the immunoreaction analysis of the luminous reaction detection immediately after the same sample to be detected and different reagents carry out continuous reaction in sequence, the efficiency of the detection analysis is improved.

The utility model provides a chemiluminescence immunoassay analyzer of instant liquid feeding and detection, it includes shell and analyzer body. The analyzer body includes:

the reaction cup is used for carrying out chemiluminescence immune reaction;

the reaction cup support is used for fixing the reaction cup, and a groove for containing the reaction cup is formed in the reaction cup support;

the reaction cup moving mechanism is used for driving the reaction cup support and the reaction cup to move along the horizontal direction, and the reaction cup moving mechanism is fixedly connected with the reaction cup support;

the liquid adding needle is used for adding chemiluminescent immunoreaction liquid into the reaction cup, is arranged above the reaction cup moving mechanism and can move up and down;

and the photomultiplier is used for detecting the chemiluminescence immune reaction in the reaction cup and is fixed on the bottom plate of the shell.

Preferably, the number of the reaction cups is determined according to the number of the samples to be analyzed and the number of the parallel immunoreaction experiments, the number of the reaction cups is at least two, and the reaction cups are arranged side by side. Further preferably, 3-9, such as 3, 4, 5, 6, 7, 8 or 9 reaction cups are provided.

Preferably, the number of the liquid adding needles is determined according to the types of the reagents participating in the immune response, and each liquid adding needle corresponds to one reagent. The liquid feeding needles are arranged in at least two rows and are arranged side by side. Further preferably, the distance between two adjacent liquid adding needles is equal to the distance between two adjacent reaction cups. When the same reaction cup passes through the liquid adding needle in sequence, different reagents can be ensured to be accurately added into the same reaction cup.

In a specific embodiment of the present invention, the chemiluminescent immunoassay analyzer body further comprises a liquid feeding pump, wherein the liquid feeding pump is connected with the liquid feeding needle in a sealing manner through a pipeline. The liquid adding pump mainly pumps the chemiluminescent immunoreaction reagent into the liquid adding needle and further injects the reagent into the reaction cup.

Preferably, the liquid adding pumps correspond to the liquid adding needles one by one, and the liquid adding pumps are fixed on the bottom plate of the shell.

Preferably, the fixing may be any one of bolting, riveting, and welding, and further preferably, bolting.

In a specific embodiment of the present invention, the reaction cup holder is used for fixing the reaction cup, and the reaction cup holder is provided with a positioning hole. Preferably, the number of the positioning holes is at least one, and more preferably two or three. The positions of the positioning holes and the grooves are relatively fixed, and when only one positioning hole is arranged, the position of the positioning hole can be determined by the aid of the grooves.

Preferably, the number of the grooves is greater than or equal to that of the reaction cups, and further preferably, the grooves correspond to the reaction cups one to one.

Preferably, the reaction cup moving mechanism is provided with a positioning pin, the position of the positioning pin corresponds to the position of the positioning hole, and the reaction cup support can be accurately fixed on the reaction cup moving mechanism through the matching of the positioning hole and the positioning pin.

Preferably, the reaction cup moving mechanism comprises a first driving motor, a first slide rail and a first slide block.

The first driving motor provides power for the horizontal movement of the reaction cup bracket;

the first sliding rail is in transmission connection with the first driving motor and can move along the horizontal direction;

the first sliding block is fixedly connected with the first sliding rail, the positioning pin is arranged on the first sliding block, and the first sliding block can horizontally move along the first sliding rail.

In another embodiment of the present invention, the chemiluminescent immunoassay analyzer body further comprises a liquid feeding needle holder. The liquid feeding needle fixing seat is fixedly connected with the liquid feeding needle, so that the liquid feeding needle and the liquid feeding needle fixing seat are ensured to be relatively fixed in position. When the liquid feeding needle fixing seat moves up and down along the vertical direction, the liquid feeding needle can be driven to move up and down synchronously.

Preferably, the fixed connection is a detachable connection or a non-detachable connection.

Preferably, the detachable connection is a threaded connection or a snap connection, further preferably a threaded connection.

Preferably, the non-detachable connection is one of a rivet connection, an adhesive connection or a welded connection, more preferably a welded connection.

Preferably, the chemiluminescent immunoassay analyzer body further comprises a liquid adding needle moving mechanism which can move up and down in the vertical direction. The liquid feeding needle moving mechanism is fixedly connected with the liquid feeding needle fixing seat, so that the liquid feeding needle fixing seat and the liquid feeding needle moving mechanism can be guaranteed to move synchronously along the vertical direction.

Preferably, the detachable connection is one of a threaded connection, a snap connection or a hinged connection, further preferably a threaded connection.

Preferably, the liquid feeding needle moving mechanism comprises a second driving motor, a second sliding rail and a second sliding block. The second driving motor provides driving force for the movement of the liquid feeding needle fixing seat, the second sliding rail is in transmission connection with the second driving motor, and the second sliding rail can move up and down along the vertical direction.

The second sliding block is fixedly connected with the second sliding rail and can move up and down along the second sliding rail.

Preferably, the liquid feeding needle fixing seat is fixedly connected with the second sliding block, so that the liquid feeding needle fixing seat can vertically move along the second sliding rail.

More preferably, the first driving motor and the second driving motor are stepping motors, and the first slide rail and the second slide rail are lead screws.

In one embodiment of the present invention, the chemiluminescent immunoassay analyzer body further comprises a base, the base is used for fixing the reaction cup moving mechanism and the liquid feeding needle moving mechanism, and the base is fixed on the bottom plate of the housing.

Preferably, the chemiluminescence immunoassay analyzer body further comprises a light shielding cover, the light shielding cover surrounds the reaction cup moving mechanism, the reaction cup support, the liquid adding needle fixing seat and the liquid adding needle moving mechanism from the periphery and the upper part, the light shielding cover is fixed on the base of the chemiluminescence immunoassay analyzer body and further fixed on the bottom plate of the shell, and the light shielding cover is provided with a photometric hole for detecting chemiluminescence immunoassay reaction by the photomultiplier.

In a specific embodiment of the present invention, the reaction cup holder is disposed on the side wall of the light shielding cover opposite to the first driving motor and close to the end of the reaction cup holder, and the reaction cup holder is disposed along the first slide rail to pass in and out the side door of the light shielding cover.

Preferably, set up first curb plate on the side door, first curb plate passes through magnetic force and adsorbs on the edge of side door, the side of reaction cup support can through magnetic force with first curb plate is connected.

Preferably, a door is arranged on the side wall of the housing, so that the reaction cup support can slide out of the housing along the first slide rail, and the reaction cup can be placed or replaced.

More preferably, the door is capable of closing after the cuvette holder has entered the housing.

Preferably, a side plate of the housing is provided with a power supply interface, and a top plate of the housing is provided with a switch button for operating the chemiluminescent immunoassay analyzer.

In another embodiment of the present invention, a circuit control panel is disposed on the back side plate of the light shielding cover for controlling the chemiluminescent immunoassay analyzer to operate according to a preset program.

The utility model has the advantages that:

the utility model discloses a chemiluminescence immunoassay analyzer can be applied to same sample that awaits measuring and need add multiple reagent according to the precedence and react, carries out the immunoreaction analysis that the luminescence detected immediately at last, has improved the efficiency of detection and analysis.

Drawings

Fig. 1 is a schematic structural view of the housing of the present invention;

the components in the figure are labeled as follows: 101-bin gate, 102-startup and shutdown button, 103-power interface;

FIG. 2 is a schematic cross-sectional view of the structure of the chemiluminescence immunoassay analyzer;

the components in the figure are labeled as follows: 201-a first driving motor, 202-a first sliding rail, 203-a first sliding block, 204-a photometric hole, 205-a liquid adding needle fixing seat, 206-a first liquid adding needle, 207-a second liquid adding needle, 208-a reaction cup, 209-a reaction cup bracket and 210-a base;

FIG. 3 is a first exploded view of the present invention;

the components in the figure are labeled as follows: 301-a second slide rail, 302-a second drive motor screw, 303-a second slider;

FIG. 4 is an enlarged schematic view of the liquid feeding needle moving mechanism of the present invention;

the components in the figures are labeled as follows: 401-a second drive motor;

FIG. 5 is a schematic view of the exploded structure of the present invention;

the components in the figures are labeled as follows: 501-a first liquid adding pump, 502-a second liquid adding pump, 503-a photomultiplier tube and 504-a control panel;

FIG. 6 is a schematic structural view of the reaction cup of the present invention before being placed;

the components in the figures are labeled as follows; 601-positioning pins;

FIG. 7 is a schematic view of the structure of the present invention after placing the reaction cup;

FIG. 8 is a schematic view of the structure of the reaction cup and the reaction cup holder of the present invention;

the components in the figure are labeled as follows: 701-positioning hole, 702-groove.

Detailed Description

The technical solutions of the present invention will be further described below with reference to the accompanying drawings and embodiments, and the advantages and features of the present invention will become more apparent as the description proceeds. It should be understood that the embodiments are illustrative only and are not limiting upon the scope of the invention.

It should be noted that the terms "upper", "lower", "left", "right", "top", "bottom", "side", and the like in the claims, the specification of the present application refer to orientations or positional relationships based on the orientations or positional relationships shown in the drawings, and it is not necessarily understood that the referred devices or components must have a specific orientation, be configured or operated in a specific orientation. In addition, "first" and "second" in this document are only used for describing similar objects and are not necessarily understood as a specific order or sequence.

In one embodiment of the present invention, the chemiluminescent immunoassay analyzer comprises a housing and a body. The shell part (see figure 1) mainly comprises a side plate, a bottom plate, a cover plate and bottom supporting legs, wherein a bin door 101 and a power supply interface 103 are arranged on the side plate, and a power on-off button 102 is arranged on the cover plate. The door 101 is a passage for detecting the entrance and exit of the sample into and out of the chemiluminescence immunoassay analyzer, the power interface 103 is used for connecting the chemiluminescence immunoassay analyzer with an external working power supply, and the on-off button 102 is a control button for the operation and stop of the chemiluminescence immunoassay analyzer.

As shown in fig. 2, 3, 4 and 5, the chemiluminescent immunoassay analyzer body includes an immune reaction system, an immune reaction system moving mechanism and a detection system. The immune reaction system comprises a reaction cup 208, a reaction cup bracket 209, a first liquid adding needle 206, a second liquid adding needle 207, a liquid adding needle fixing seat 205, a first liquid adding pump 501 and a second liquid adding pump 502. The immune reaction system moving mechanism comprises a reaction cup moving mechanism moving along the horizontal direction and a liquid adding needle moving mechanism moving along the vertical direction. The reaction cup moving mechanism comprises a first driving motor 201, a first slide rail 202 and a first slide block 203. The liquid adding needle moving mechanism comprises a second driving motor 401, a second driving motor lead screw 302, a second slide rail 301 and a second slide block 303. The detection system is used for detecting the luminescence phenomenon in the immune reaction process and comprises a photomultiplier 503 and a photometric hole 204.

As shown in fig. 2 and fig. 8, in the immunoreaction system, the reaction cup 208 is used for containing the sample to be detected and the reaction reagent. At least two reaction cups 208 can be arranged in a chemiluminescence immune analyzer at the same time, and the number of the specific reaction cups 208 is set according to the number of samples to be detected and the number of parallel experiments of each sample to be detected. The cuvettes 208 for participating in the chemiluminescent immune reaction are preferably arranged side-by-side. The reaction cups in FIG. 2 are 8 in number and arranged in a row. The cuvette holder 209 is used to hold and support the cuvette 208, thereby ensuring the stability of the cuvette 208. A groove 702 is provided on the cuvette holder 209, and the groove 702 is mainly used to fix the cuvette 208 on the cuvette holder 209. The number of the grooves 702 is greater than or equal to the number of the reaction cups 208, and preferably, the grooves 702 correspond to the reaction cups 208 one to one, for example: the number of grooves 702 in fig. 8 is 8. All the grooves 702 are arranged side by side, and the distance between adjacent grooves 702 is the same, thereby ensuring that the distance between adjacent reaction cups 208 is also the same.

In an embodiment of the present invention, the cuvette holder 209 is further provided with positioning holes 701, as shown in fig. 8, the positioning holes 701 are disposed on one side of the parallel-arranged grooves 702, the number of the positioning holes 701 is at least one, and preferably two or three positioning holes 701 may be provided. The positions of the positioning holes 701 and the grooves 702 are fixed relatively, and when only one positioning hole 701 is provided, the grooves 702 can be used to assist in determining the position of the positioning hole 701.

As shown in fig. 2 and 5, the liquid adding needle holder 205, the first liquid adding needle 206, the second liquid adding needle 207, the first liquid adding pump 501 and the second liquid adding pump 502 are used for adding a reaction reagent into the reaction cup 208, so that the sample substrate to be detected and the reaction reagent react with each other to generate a luminescence phenomenon for detecting the reaction. First liquid feeding needle 206 and second liquid feeding needle 207 and liquid feeding needle fixing base 205 fixed connection, can adopt detachable connected mode between liquid feeding needle and the liquid feeding needle fixing base 205, such as threaded connection or buckle connection, preferably threaded connection. The filling needle and filling needle holder 205 may also be non-detachably connected, such as one of a riveted, glued or welded connection, preferably a welded connection. The first liquid adding needle 206 and the first liquid adding pump 501 are hermetically connected through a pipeline, and in order to adapt to the vertical up-and-down movement of the first liquid adding needle 206, the pipeline can be a hose, such as a silicone tube. The second filling needle 207 and the second filling pump 502 are also hermetically connected through a pipe. When the priming pump is connected to the reagent container, the reagent may be pumped through the priming needle and further into the reaction cuvette 208. The number of the liquid adding needles is set according to the types of the reaction reagents, and preferably, one liquid adding needle corresponds to one reaction reagent. The number of the liquid adding pumps is preferably the same as that of the liquid adding needles, and the liquid adding pumps and the liquid adding needles correspond to one another. When the number of the liquid adding needles is more than or equal to 2, the liquid adding needles are arranged side by side, and the distance between two adjacent liquid adding needles is equal to the distance between two adjacent reaction cups 208. When the reaction cups 208 move at a constant speed along the horizontal direction, the reagents in the liquid adding needles can be accurately added into the adjacent reaction cups 208 according to the sequence.

As shown in fig. 2 and 3, the cuvette moving mechanism includes a first driving motor 201, a first slide rail 202, and a first slider 203. The first driving motor 201 provides power for the horizontal movement of the reaction cup support 209, and the first driving motor 201 is in transmission connection with the first slide rail 202. When the first driving motor 201 is a stepping motor, the first slide rail 202 is a lead screw. The first slide rail 202 and the first slide block 203 are fixedly connected, and can be detachably connected, such as one of a threaded connection, a snap connection or a hinged connection, and preferably are connected through threads. Alternatively, the non-detachable connection may be one of a rivet connection, an adhesive connection or a welded connection, preferably a welded connection. The first sliding block 203 can move horizontally left and right along the first sliding rail 202 under the driving of the first sliding rail 202. The first slide block 203 is provided with positioning pins 601 (see fig. 6), and the positioning pins 601 correspond to the positioning holes 701 of the cuvette holder 209 one to one (see fig. 8). The reaction cup support 209 is fixed on the first slide block 203 through the matching of the positioning pin 601 and the positioning hole 701, so that when the first slide block 203 moves left and right along the horizontal direction, the reaction cup support 209 can be driven to move synchronously, and further the reaction cup 208 is driven to move synchronously and horizontally.

As shown in fig. 2, 3 and 4, the filling needle moving mechanism includes a second driving motor 401, a second driving motor lead screw 302, a second slide rail 301 and a second slider 303. The second driving motor 401 provides power for the filling needle fixing seat 205 to move up and down along the vertical direction, and the second driving motor 401 is in transmission connection with the second slide rail 301. When the second driving motor 401 is a stepping motor, the second slide rail 301 is a lead screw. The second slide rail 301 and the second slide block 303 are fixedly connected, and a detachable connection, such as one of a threaded connection, a snap connection or a hinged connection, is selected, and is preferably a threaded connection. Alternatively, the non-detachable connection may be one of a rivet connection, an adhesive connection or a welded connection, preferably a welded connection. The second slider 303 can vertically move up and down along the second slide rail 301 under the driving of the second slide rail 301. The second sliding block 303 is fixedly connected with the liquid feeding needle fixing seat 205, for example, in a threaded connection, a snap connection, a rivet connection, a welding connection, and the like. Thereby fix liquid feeding needle fixing base 205, liquid feeding needle and second slide rail 301 together, fix the liquid feeding needle on second slider 303 for when second slider 303 vertically reciprocated along second slide rail 301, can drive liquid feeding needle fixing base 205 synchronous motion, and then drive the synchronous vertical up-and-down motion of liquid feeding needle.

As shown in fig. 2 and 5, the detection system of the chemiluminescence immune reaction includes a photomultiplier 503 and a photometric well 204. When the cuvette containing the sample to be detected and the immunoreaction reagent passes through the photometric hole 204, the luminescence phenomenon generated by the immunoreaction is detected by the photomultiplier 503, and then the corresponding data is transmitted to the data analysis system, thereby completing the detection and analysis of the chemiluminescence immunoreaction. The photomultiplier 503 is disposed on the base 210 of the chemiluminescent immunoassay analyzer body. The light measuring hole 204 is arranged on the back side plate of the light avoiding cover.

As shown in fig. 2 and 3, the chemiluminescent immunoassay analyzer body also includes a base 210 fixedly attached to the floor of the chemiluminescent immunoassay analyzer housing. The fixing mode of the two can be one of the connection modes of screw connection, snap connection, rivet connection, welding and the like, and the screw connection is preferably adopted. The base 210 is used for fixing the reaction cup moving mechanism and the liquid adding needle moving mechanism, thereby ensuring the stability and safety of the immunoassay analyzer during operation.

As shown in fig. 3 and 5, the chemiluminescence immunoassay analyzer body further comprises the light shielding cover. The reaction cup moving mechanism, the reaction cup 208, the reaction cup support 209, the liquid adding needle fixing seat 205 and the liquid adding needle moving mechanism are surrounded by the light shielding cover from the periphery and the upper part, and the side plate and the top plate of the light shielding cover are fixedly connected together by adopting connection modes such as threaded connection, buckling connection, rivet connection, welding and the like, preferably threaded connection. The light shield is fixed to the base 210 of the chemiluminescent immunoassay analyzer body and, in turn, to the floor of the housing of the chemiluminescent immunoassay analyzer.

As shown in fig. 3, a side door is provided on the side wall of the light shielding cover facing the first driving motor 201 and near the end of the reaction cup holder 209, wherein the reaction cup holder 209 enters and exits the light shielding cover along the first slide rail 202. Set up the first curb plate that matches with the side door shape on the side door, first curb plate passes through magnetic force and adsorbs in the edge of side door, and reaction cup support 209 links together with first curb plate accessible magnetic force adsorption. When the cuvette holder 209 slides out of the side door of the light-shielding cover along the first slide rail 202, the first side plate is pushed by the cuvette holder 209 to separate from the side door of the light-shielding cover, and is adsorbed together with the cuvette holder 209 and moves toward the housing of the chemiluminescent immunoassay analyzer. On the lateral wall of the housing of the chemiluminescence immunoassay analyzer, a bin gate 101 is arranged, a second lateral plate matched with the bin gate 101 in shape is adsorbed on the edge of the bin gate 101 through magnetic force, and the second lateral plate and the first lateral plate can also be adsorbed together through magnetic force. When the cuvette holder 209 slides out of the door 101 along the first slide rail 202 together with the first side plate, the cuvette holder 209 pushes the first side plate and the second side plate to horizontally move out of the door 101 together, and the cuvette is placed or replaced outside the housing of the chemiluminescent immunoassay analyzer. When the cuvette holder 209 is moved toward the inside of the chemiluminescent immunoassay analyzer while carrying the cuvette, the cuvette holder 209 enters the housing, the second side plate is attached to the edge portion of the door 101, and the door 101 is closed. First curb plate and second curb plate alternate segregation, reaction cup support 209 continues to move to the chemiluminescence immunoassay analyzer is inside, when reaction cup support 209 removes the side door to avoiding on the light cover, first curb plate adsorbs on the side door, reaction cup support 209 breaks away from each other with first curb plate, and the side door is closed, forms the light-resistant space in avoiding the light cover. The cuvette holder 209 continues to move into the light shielding case, and the immuno-luminescence reaction and detection are started.

As shown in fig. 5, a circuit control panel 504 is disposed on the back side plate of the light shielding cover, and after an external power source is turned on, the operation of the chemiluminescence immune analyzer can be controlled by a preset program stored in the circuit control panel 504.

In order to facilitate understanding of the technical scheme of the utility model, the following detection experiment taking a sample to be detected as an example, wherein two reaction reagents (A and B) are added according to the sequential steps to carry out the luminescence immune reaction, provides the operation method of the chemiluminescence immune analyzer, and comprises the following specific steps:

1. and (4) sample adding. The external power is firstly switched on through the power interface 103, and the circuit control panel 504 is powered on and operates. Then, the on-off button 102 is pressed, the bin door 101 is opened, the first driving motor 201 forwards drives the first slide rail 202 to move towards the outside of the chemiluminescence immunoassay analyzer, and the first slide block 203 and the reaction cup support 209 are synchronously driven to slide outside the chemiluminescence immunoassay analyzer. Then, the cuvette 208 is placed on the cuvette holder 209, and then 8 samples to be tested are added to the cuvette 208 in the order of increasing the number.

2. And (6) detecting and analyzing. The on-off button 102 is pressed again, the first driving motor 201 rotates reversely, the first slide rail 202 is driven to move towards the inside of the chemiluminescence immunoassay analyzer, the first slide block 203, the reaction cup bracket 209 and the reaction cup 208 are synchronously driven to slide into the chemiluminescence immunoassay analyzer, and then the side door is closed. Meanwhile, the second driving motor 401 forwards drives the second slide rail 301 to vertically move upwards, and synchronously drives the second slide block 303, the liquid feeding needle fixing seat 205 and the liquid feeding needle to vertically move upwards, so that the liquid outlet of the liquid feeding needle is higher than the opening of the reaction cup 208. When the No. 1 reaction cup moves to the position below the second liquid adding needle 207, the second liquid adding pump 502 operates to add the reaction reagent A into the No. 1 reaction cup for the first step of chemical reaction. Then the first slide rail 202 continues to slide, when the No. 1 reaction cup moves to the position below the first liquid adding needle 206, the first liquid adding pump 501 operates, and the reaction reagent B is added into the No. 1 reaction cup to perform the second step of chemical reaction. Meanwhile, the No. 2 reaction cup moves to the position below the No. 2 liquid adding needle, the second liquid adding pump 502 operates, the reaction reagent A is added into the No. 2 reaction cup, and the first-step chemical reaction is carried out in the No. 2 reaction cup. Then, the first slide rail 202 continues to slide, and when the reaction cup No. 1 moves to the position of the photometric hole 204, the photomultiplier 503 operates to detect the luminescence of the reactant in the reaction cup No. 1. Meanwhile, the No. 2 reaction cup moves to the position below the No. 1 liquid adding needle, the first liquid adding pump 501 operates, the reaction reagent B is added into the No. 2 reaction cup, and the second step of chemical reaction is carried out in the No. 2 reaction cup. Along with the continuous motion of first slide rail 202 of first driving motor 201 drive, 8 reaction cups add reactant A and B in proper order, move to photometry hole 204 department again, and photomultiplier detects and detects the luminous reactant in proper order, and the 8 th reaction cup detects and accomplishes. And simultaneously, the detection data is transmitted to a computer connected with the chemiluminescence immunoassay analyzer to synchronously analyze the data.

3. And (5) shutting down the machine. The switch button 102 is pressed first, the chemiluminescence analyzer operates according to a preset program, the first liquid adding pump 501 and the second liquid adding pump 502 are closed first, then the second driving motor 401 rotates reversely to drive the second slide rail 301 to move vertically downwards to drive the second slide block 303, the liquid adding needle fixing seat 205 and the liquid adding needle to synchronously move vertically downwards, and after the liquid adding needle is reset, the second driving motor 401 stops operating. Then the first driving motor 201 rotates forward to drive the first slide rail 202 to move towards the exterior of the chemiluminescence immunoassay analyzer, and synchronously drive the first slide block 203, the reaction cup support 209 and the reaction cup 208 to move towards the exterior of the chemiluminescence immunoassay analyzer, when the reaction cup 208 moves out of the door 101, the first driving motor 201 stops operating, and the operator takes down the reaction cup 208 from the reaction cup support 209. The switch button 102 is pressed again, the first driving motor 201 positively drives the first slide rail 202, the first slide block 203 and the reaction cup holder 209 to move into the chemiluminescence immunoassay analyzer, and when the first slide block 203 and the reaction cup holder 209 are reset, the first driving motor 201 stops operating, and the bin gate 101 is closed. The chemiluminescent immunoassay analyzer was shut down and then the external power was disconnected.

The above-mentioned only be the embodiment of the utility model discloses a not consequently restriction the patent scope of the utility model, all utilize the equivalent structure transform of the content of the specification made of the utility model, or direct or indirect application is in other relevant technical field, and all the same reason is included in the patent protection scope of the utility model.

Claims

1. A chemiluminescence immunoassay analyzer capable of adding liquid and detecting instantly comprises a shell and an analyzer body, and is characterized in that: the analyzer body includes:

the reaction cup is used for carrying out chemiluminescence immune reaction;

the liquid adding needle is used for adding a chemiluminescent immunoreaction reagent into the reaction cup, is arranged above the reaction cup moving mechanism and can move up and down;

2. The chemiluminescent immunoassay analyzer of claim 1, wherein: the number of the reaction cups is at least two, and the reaction cups are arranged side by side.

3. The chemiluminescent immunoassay analyzer of claim 1 or 2, wherein: the liquid feeding needle is at least two, and the liquid feeding needle sets up side by side.

4. The chemiluminescent immunoassay analyzer of claim 3, wherein: the distance between two adjacent liquid adding needles is equal to the distance between two adjacent reaction cups.

5. The chemiluminescent immunoassay analyzer of claim 1, wherein: the analyzer body further comprises:

and the liquid adding pump is hermetically connected with the liquid adding needle through a pipeline, corresponds to the liquid adding needle one by one, is fixed on the bottom plate of the shell and can sequentially pump the chemiluminescent immunoreaction reagent into the liquid adding needle and the reaction cup.

6. The chemiluminescent immunoassay analyzer of claim 1, wherein: the reaction cup support is provided with a positioning hole, the reaction cup moving mechanism is provided with a positioning pin, and the reaction cup support can be accurately fixed on the reaction cup moving mechanism through the matching of the positioning hole and the positioning pin.

7. The chemiluminescent immunoassay analyzer of claim 6, wherein: the reaction cup moving mechanism comprises:

8. The chemiluminescent immunoassay analyzer of claim 1, wherein: the number of the grooves is more than or equal to that of the reaction cups.

9. The chemiluminescent immunoassay analyzer of claim 8, wherein: the grooves correspond to the reaction cups one to one.

10. The chemiluminescent immunoassay of any one of claims 1-9, wherein: the analyzer body further comprises a light-shielding cover, the light-shielding cover surrounds the reaction cup moving mechanism, the reaction cups, the reaction cup support, the liquid feeding needles, the liquid feeding needle fixing seats and the liquid feeding needle moving mechanism from the periphery and the upper part, the light-shielding cover is fixed on the bottom plate of the shell, and the light-shielding cover is provided with a photometric hole for detecting the chemiluminescence immune reaction by the photomultiplier tube.