CN217773386U - Solvent crystallization type bulk drug conical filtering washing dryer - Google Patents

Abstract

The utility model relates to a menstruum crystallization type bulk drug toper filters washing desiccator, including last barrel and lower cone, last barrel with lower cone can dismantle the connection from top to bottom, its characterized in that: the second heat preservation cover body is fixed on the outer wall of the lower cone, the outer walls of two sides of the first heat preservation cover body are respectively fixed with a supporting seat, and the upper cylinder body is fixed on the support through the supporting seats of two sides of the first heat preservation cover body. This design makes filter area promote by a wide margin through the straight section formula filter that sets up and conical filter, and conical filter's cone filter area compares with the equipment of equal diameter moreover, and its cone filter area is 2 ~ 2.5 times flat, and the toper filtering component adopts multilayer high strength sintering filter screen welded fastening on the metal support, then whole fastening is on the container chassis, and the material contact surface is the glossy top inoxidizing coating of 6 layers metal sintering net, avoids the material to remain the problem.

Description

Solvent crystallization type bulk drug conical filtering washing dryer

Technical Field

The utility model relates to the technical field of medical equipment, concretely relates to menstruum crystallization type bulk drug toper filters washing desiccator.

Background

In the production process of the solvent crystallization bulk drug, the processes of solid-liquid separation, purification and drying can be performed by centrifugal separation and purification, single cone or oven drying, and part of the drug can be completed by a filtering, washing and drying device; the traditional filtering, washing and drying equipment can complete multiple functions in the production process through one piece of equipment, can partially solve the functions of safety, environmental protection, automation and the like, has certain advanced performance, and has very wide application in the chemical industry and the pharmaceutical industry; however, due to the technical limitation of equipment, in the practical production application, a large amount of material residues, liquid leakage, low drying efficiency, manual intervention and other risks exist, the risks also bother many pharmaceutical workers, sometimes, according to practical use experience, the problem of low drying efficiency is solved by adding a drying device behind a filtering and drying device, the problem of residual materials is solved by manually intervening discharging materials during discharging, and the like, but the measures only can increase the operation cost and reduce the production quality of medicines, and can treat symptoms and root causes, and meanwhile, unpredictable production hidden dangers can be brought.

The prior multifunctional filtering, washing and drying machine for refining and purifying solvent crystallization bulk drugs in the pharmaceutical industry has various types, but has the following defects:

(1) The materials cannot be stirred quickly and uniformly, the stirring and turning mode is typically planar pushing, the contact surface of the materials with the jacket is limited, and the bottom filter layer is not involved in turning from certain retention, if the materials are slightly viscous, the effect is greatly reduced;

(2) The washing effect is poor, the conventional stirrer cannot crush and loosen the crystal filter cake, so that the crystal filter cake is mixed with the cleaning liquid to be in a pasty or sludge state, and the crystals are stirred and washed by stirring;

(3) The filtration is not thorough, the cake material layer is thick, the filtration area is small, the filtration is needed to be used for many times when the high-requirement and high-efficiency product is produced, and the time and the resources are wasted;

(4) The drying rate is slow and the heat transfer effect is relatively low.

(5) The closed automatic turnover of the materials cannot be realized.

(6) The main limitation of traditional flat-bottom filtration equipment such as three-in-one pot and vertical drier is that when unloading the material at last, the operation action is complicated, and is difficult to arrange the material totally clean moreover, and the process of unloading not only time very long each time causes a large amount of material to remain in addition, influences the yield, also causes the phenomenon of revealing of organic solvent easily.

(7) The sealing effect of the conventional conical filter and the upper tank body and the lower tank body is poor, and the crystal leakage problem frequently occurs, so that the product yield is reduced. In order to prevent the stirring paddle from scraping the filter medium in the operation of the equipment, a protective orifice plate is arranged between the stirring paddle and the filter medium. Therefore, after the drying and discharging are finished, a large amount of residual powder is left on the filter medium, and the product yield is seriously influenced.

(8) A large amount of residual powder is remained in the interlayer of the protective orifice plate and the filter medium, the protective orifice plate is easy to block, the washing liquid is difficult to filter, the quality of the produced product is difficult to guarantee, and the unqualified condition of the product also sometimes occurs. Residual washing liquid at the bottom of the cone cannot be discharged, and the moisture content of a filter cake is high. The drying time of the material is increased, and the quality of the product is reduced.

Disclosure of Invention

The utility model designs a solvent crystallization bulk drug conical filtering washing dryer for solving the problems, which greatly increases the filtering area through the straight section type filter and the conical filter, and the filtering area of the cone of the conical filter is 2-2.5 times of the flat bottom compared with the equipment with the same diameter; the conical filtering component is welded and fixed on the metal support by adopting a plurality of layers of high-strength sintered filter screens, then is integrally fastened on the container chassis, and the material contact surface is a top protective layer with 6 layers of metal sintered screens, so that the problem of material residue is avoided.

In order to solve the technical problem, the utility model provides a dissolvent crystallization type bulk drug toper filters washing desiccator, including last barrel and lower cone, last barrel with lower cone from top to bottom can dismantle connection, its characterized in that: the upper end of the upper cylinder is provided with a sealing head connected with the upper cylinder into a whole, the lower end of the lower cone is also provided with a bottom plate connected with the lower cone into a whole, the outer wall of the upper cylinder is fixedly provided with a spiral first heating pipe, the outer wall of the lower cone is provided with a conical spiral second heating pipe, the cross sections of the first heating pipe and the second heating pipe are both in a semicircular shape, the lower end of the first heating pipe is communicated with the upper end of the second heating pipe, the upper end of the first heating pipe is connected with a heating medium inlet pipe, the lower end of the second heating pipe is connected with a heating medium outlet pipe, the outer side of the first heating pipe is provided with a first supporting seat Wen Zhaoti, the first supporting seat Wen Zhaoti is fixed on the outer wall of the upper cylinder, the outer side of the second heating pipe is also provided with a second heat preservation cover body, the second heat preservation cover body is fixed on the outer wall of the lower cone, the outer walls on two sides of the first heat preservation cover body are respectively fixedly provided with a first supporting seat fixed on the support, the lower end of the upper cylinder penetrates through the lower support and is connected with the lower support of the conical support, the conical straight section of the lower cone, the upper cone, the discharge cone is further provided with the lower end of the discharge cone, and the lower cone, the lower cone is provided with the lower cone, and the lower cone, and the upper end of the discharge cone is provided with the discharge cone.

Further: the straight section formula filter be straight cylinder filter screen, the upper end of straight cylinder filter screen is fixed on the inner wall of last barrel through first metal-back, the cone filter is the sectional type filter, and it comprises first toper filter screen and second toper filter screen, first toper filter screen with second toper filter screen from the top down set gradually under in the cone, the upper end of first toper filter screen links to each other with the lower extreme of straight cylinder filter screen, the lower extreme of first toper filter screen is provided with the second metal-back, the upper end of second toper filter screen is provided with the third metal-back that is connected with the second metal-back, be provided with the second supporting seat that is used for supporting fixed third metal-back on the inner wall of cone down, first toper filter screen with second toper filter screen pass through the cooperation of second metal-back and third metal-back and second supporting seat and fix under in the cone.

And further: first toper filter screen with the toper filtering component that second toper filter screen formed adopts multilayer high strength sintering filter screen welded fastening on the metal support, then whole fastening is on the container chassis, the material contact surface is the glossy top inoxidizing coating of 6 layers of metal sintering net, avoids the material to remain the problem.

And further: the upper barrel body and the lower cone body are internally provided with double internal heating helical ribbon stirrers which are variable pitch helical ribbon stirrers and specifically comprise a rotating shaft, helical ribbons, helical ribbon supporting rods and a stirring motor, the helical ribbons are provided with two helical ribbons, the two helical ribbons spirally surround the outer side of the rotating shaft in the lower cone body, the upper end of the rotating shaft penetrates through the end socket and extends into the supporting frame, the supporting frame is fixed at the top of the end socket, the stirring motor is connected with a reduction gearbox, the reduction gearbox is detachably connected at the top of the supporting frame through an installing plate, the rotating shaft is further connected with a transmission shaft through a coupler, the transmission shaft sequentially penetrates through the supporting frame and the reduction gearbox, the transmission shaft further drives the transmission shaft to rotate through the reduction gearbox and the stirring motor, two spiral shell areas all are again through a plurality of spiral shell area bracing pieces and pivot fixed connection, pivot, transmission shaft, spiral shell area and spiral shell area bracing piece all be hollow form, the inner space of spiral shell area is linked together through the inner space of spiral shell area bracing piece and the inner space of pivot, stretch out the one end of the transmission shaft of reducing gear box and install mechanical seal structure rotary joint, mechanical seal structure rotary joint links to each other with hot water line and cooling water pipe respectively, mechanical seal structure rotary joint still links to each other with the hot water outlet pipe, the outside of mechanical seal structure rotary joint, agitator motor and reducing gear box still is provided with the sealed cover body 22, the sealed cover body detachably fix on the mounting panel, hot water line, cooling water pipe and hot water outlet pipe pass the sealed cover body respectively and link to each other with mechanical seal structure rotary joint.

And further: the outer side of the lower end of the first heat preservation Wen Zhaoti is provided with a first pipeline connecting flange, the first pipeline connecting flange extends into the first heat preservation cover body and is communicated with the first heating pipe, the outer side of the upper end of the second heat preservation cover body is provided with a second pipeline connecting flange, the second pipeline connecting flange extends into the second heat preservation cover body and is communicated with the second heating pipe, and the first pipeline connecting flange is connected with the second pipeline connecting flange through a U-shaped connecting pipeline.

And further: the lifting mechanism comprises a servo motor, a lead screw and a flexible part, the servo motor is fixed at the upper end of the lower vertebral body through a mounting seat, the lead screw is vertically arranged, the lower end of the lead screw is connected with the servo motor, the upper end of the lead screw penetrates through a support, and the support is connected to the lead screw through the flexible part.

And further: the bottom plate is also provided with a plunger type sampling valve, and the top of the seal head is also provided with a dust catcher.

After the structure is adopted, the utility model discloses the beneficial effect who has does:

(1) The filtration area is greatly increased: the filtering area of the cone is set, the diameter of the equipment is the same, and the filtering area of the cone is 2-2.5 times of that of the flat bottom;

(2) The solid-liquid separation is thorough, and the material residue can be avoided: the conical filter adopts a sectional design, has high structural strength, has small deformation during pressure filtration, and improves the filtration effect; can realize that the multistage independently filters, segmentation anti-purge etc. solid-liquid separation is thorough, can not produce and filter the short circuit problem. The filter screen component is welded and fixed on the metal support by adopting a plurality of layers of high-strength sintered filter screens, and then is integrally fastened on the container chassis, and the material contact surface is a top protective layer with 6 layers of metal sintered screens, so that the problem of material residue is avoided.

(3) Automatic and complete discharging: the discharge port is arranged at the lowest position of the equipment, the material is automatically and completely discharged, and the general loose materials can be discharged without residue by combining the positive and negative rotation of internal stirring;

(4) The drying effect is excellent: the spiral stirring of heating toper in the matching in the trinity desiccator, its polytropy design can let different characteristic materials all can reach the three-dimensional effect of turning of ideal, and the cover heat transfer that presss from both sides of equipment main part fully utilizes, and lets every partial material fully heat transfer all.

Drawings

The present invention will be described in further detail with reference to the accompanying drawings and specific embodiments.

Fig. 1 is a schematic structural diagram of the present invention.

Fig. 2 is an internal structure diagram of the present invention.

Fig. 3 is an enlarged view of a in fig. 2.

Fig. 4 is an enlarged view of B in fig. 2.

Detailed Description

The solvent crystallization bulk drug tapered filtration washing dryer as shown in figure 1 and figure 2 comprises an upper cylinder 1 and a lower cone 3, the upper cylinder body is detachably connected with the lower cone body up and down, the upper end of the upper cylinder body is provided with an end enclosure 2 which is connected with the upper cylinder body into a whole, the lower end of the lower cone is also provided with a bottom plate 6 which is connected with the lower cone into a whole, the outer wall of the upper cylinder is fixed with a spiral first heating pipe 4, the outer wall of the lower cone is provided with a conical spiral second heating pipe 5, the sections of the first heating pipe and the second heating pipe are both in a semicircular shape, the lower end of the first heating pipe is communicated with the upper end of the second heating pipe, the upper end of the first heating pipe is connected with a heating medium inlet pipe 10, the lower end of the second heating pipe is connected with a heating medium output pipe 13, the outer side of the first heating pipe is provided with a first heat-preserving pipe Wen Zhaoti 14, the first heat preservation Wen Zhaoti is fixed on the outer wall of the upper cylinder, the outer side of the second heating pipe is also provided with a second heat preservation cover body 15, the second heat preservation cover body is fixed on the outer wall of the lower cone, the outer walls of the two sides of the first heat preservation cover body are respectively fixed with a first supporting seat 8, the upper cylinder body is fixed on a bracket 7 through first supporting seats at two sides of a first heat-insulating cover body, the lower end of the upper cylinder body passes through the bracket and is connected with a lower cone body through a flange component, the bottom of the bracket is also provided with a plurality of upright posts 16, a lifting mechanism is also arranged between the lower cone and the bracket, a straight section type filter 26 is arranged in the upper cylinder body, a conical filter 27 is arranged in the lower cone body, the lower end of the straight section type filter is connected with the upper end of the conical filter, and a discharge valve 18 is installed at the bottom of the bottom plate. The discharge valve is of a novel discharge ball valve structure, and a sealing ball body is tightly attached to the plane of the bottom plate, so that dead-angle-free discharge is realized; the valve cover and the valve body adopt an easy-opening structure, so that the valve cover and the valve body are convenient to open and clean; the valve cover and the valve body can realize automatic opening and discharging, the discharging time can be set, and the discharging valve can be cleaned on line, so that the GMP requirement is met; the valve head and the tank body joint flange are in soft seal by adopting a formed O-shaped Teflon ring, so that the medicine residue is reduced, the cleaning is convenient, and the sealing reliability is ensured.

The straight section type filter shown in fig. 2, fig. 3 and fig. 4 is a straight cylinder type filter screen, the upper end of the straight cylinder type filter screen is fixed on the inner wall of the upper cylinder body through a first metal support 28, the conical filter is a sectional type filter which is composed of a first conical filter screen 27-1 and a second conical filter screen 27-2, the first conical filter screen and the second conical filter screen are sequentially arranged in the lower cone body from top to bottom, the upper end of the first conical filter screen is connected with the lower end of the straight cylinder type filter screen, the lower end of the first conical filter screen is provided with a second metal support 30-1, the upper end of the second conical filter screen is provided with a third metal support 30-2 connected with the second metal support, the inner wall of the lower cone body is provided with a second support seat 29 for supporting and fixing the third metal support, the first conical filter screen and the second conical filter screen are fixed in the lower cone body through the second metal support and the cooperation of the third metal support seat, the straight cylinder type filter screen, the first conical filter screen and the second conical filter screen are composed of six metal sintered metal layers, and two layers, two filter layers, one layer and two actual filter layers and two layers are sintered layers and two protective layers. The utility model has the advantages that the filtering area is greatly increased by the straight section type filter and the conical filter, and compared with the equipment with the same diameter, the conical filtering area of the conical filter is 2-2.5 times of that of the flat bottom; the conical filter adopts a sectional design, has high structural strength, has small deformation during pressure filtration, and improves the filtration effect; the design can realize multi-section independent filtration, sectional reverse purging and the like, the solid-liquid separation is thorough, and the problem of filtration short circuit cannot be caused; the filter screen component is welded and fixed on the metal support by adopting a plurality of layers of high-strength sintered filter screens, and then is integrally fastened on the support chassis, and the material contact surface is a smooth top protective layer of 6 layers of metal sintered screens, so that the problem of material residue is avoided; a special sealing structure is adopted between the conical filter and the inner wall of the lower cone body, FEP is coated outside O-type Ethylene Propylene Diene Monomer (EPDM) is adopted for an upper sealing gasket and a lower sealing gasket of the filter sintering plate, and the sealing structure reduces medicine residue, is convenient to clean, ensures reliable sealing and does not cause any leakage.

As shown in figure 1, the upper barrel and the lower cone are internally provided with double internal heating helical ribbon stirrers which are variable pitch helical ribbon stirrers and specifically comprise a rotating shaft 20, helical ribbons, helical ribbon support rods and a stirring motor 23, the helical ribbons are provided with two helical ribbons, the two helical ribbons spirally surround the outer side of the rotating shaft in the lower cone, the upper end of the rotating shaft penetrates through the end socket and extends into a support frame 19, the support frame is fixed at the top of the end socket, the stirring motor is connected with a reduction gearbox, the reduction gearbox is detachably connected at the top of the support frame through an installation plate 21, the rotating shaft is further connected with a transmission shaft through a coupler, the transmission shaft sequentially penetrates through the support frame and the reduction gearbox, the transmission shaft further drives the transmission shaft to rotate through the reduction gearbox and the stirring motor, two spiral shell areas all are again through a plurality of spiral shell area bracing pieces and pivot fixed connection, pivot, transmission shaft, spiral shell area and spiral shell area bracing piece all be hollow form, the inner space of spiral shell area is linked together through the inner space of spiral shell area bracing piece and the inner space of pivot, stretch out the one end of the transmission shaft of reducing gear box and install mechanical seal structure rotary joint 24, mechanical seal structure rotary joint links to each other with hot water pipeline and cooling water pipe respectively, mechanical seal structure rotary joint still links to each other with the hot water outlet pipe, the outside of mechanical seal structure rotary joint, agitator motor and reducing gear box still is provided with the sealed cover body 22, sealed cover body detachably fix on the mounting panel, hot water pipeline, cooling water pipe and hot water outlet pipe pass the sealed cover body respectively and link to each other with mechanical seal structure rotary joint. The utility model discloses a reduction of the sealed cover body that sets up has increased the practicality to the pollution of material. The sealing of the stirring shaft and the container adopts a set of special sterile dry-type double-end-face mechanical seal with an abradant collecting cup, so that the pollution to materials is reduced; the stirring rake is equipped with the explosion-proof drive variable frequency motor of variable frequency speed governing, explosion-proof grade: exdIIBT4, protection rating: IP55; the stirring shaft adopts an internal heating helical ribbon structure, is natural and smooth, ensures the minimum damage degree to the crystal form of the product, increases the heating area and improves the drying speed; the double internal heating helical ribbon stirrers are uniformly stressed in the operation process, the main shaft rotation disturbance deformation is small, and the heat transfer area is large; variable pitch helical ribbon stirrer: three-dimensional compound motion of axial motion, radial motion and circumferential motion of the materials in the machine is improved, so that the stirring and mixing effects of the materials reach the optimal state; the lower shaft end is provided with an adjustable scraper which is tightly attached to the cone bottom plate, so that the stirring and mixing effects of materials at the cone bottom are improved.

As shown in fig. 1 and 2, a first pipeline connecting flange is arranged on the outer side of the lower end of the first heat-preserving cover Wen Zhaoti, the first pipeline connecting flange extends into the first heat-preserving cover and is communicated with the first heating pipe, a second pipeline connecting flange is arranged on the outer side of the upper end of the second heat-preserving cover, the second pipeline connecting flange extends into the second heat-preserving cover and is communicated with the second heating pipe, and the first pipeline connecting flange is connected with the second pipeline connecting flange through a U-shaped connecting pipeline.

The lifting mechanism shown in fig. 1 comprises a servo motor 12, a lead screw 11 and a flexible, wherein the servo motor is fixed at the upper end of a lower vertebral body through a mounting seat, the lead screw is vertically arranged, the lower end of the lead screw is connected with the servo motor, the upper end of the lead screw penetrates through a support, and the support is connected to the lead screw through the flexible.

The bottom plate is also provided with a plunger type sampling valve which is used for online sampling and meets the GMP requirement; the sealing element at the rear end of the sampling valve body, which is contacted with the material, adopts an O-shaped ring with FEP coated silicon rubber; the plunger type sampling valve can also be cleaned on line.

The top of the end socket shown in fig. 1 is also provided with a dust catcher 25, the design parameters of which are consistent with those of the filtering, washing and drying tank body, such as the same pressure and temperature, the same material and the same finish treatment; the filtering filter element is made of five layers of metal sintering nets, the material of the filter element is 316L, and the filtering precision is 10 microns; the dust catcher is provided with a heating, vacuum and high-pressure nitrogen connecting pipe, and can integrate the functions of heating, heat preservation, back flushing, vacuumizing and the like.

The top in the end socket is also provided with 3 360-degree cleaning spray balls for cleaning in the tank, and a removable sleeve structure is adopted, so that the GMP requirement is met; the top in the end socket is also provided with a cleaning rod of a sleeve structure, and the cleaning rod is used for cleaning the lower part of the mechanical seal and the corrugated pipe; the utility model discloses an adopt above-mentioned design to play 360 no dead angles and wash.

To sum up, the utility model discloses an adopt above-mentioned structure its beneficial effect who has to do: (1) the filtration area is greatly increased: the filtering area of the cone is set, the diameter of the cone is equal to that of the equipment, and the filtering area of the cone is 2-2.5 times of that of the flat bottom; (2) the solid-liquid separation is thorough, and the material residue can be avoided: the conical filter adopts a sectional design, has high structural strength, has small deformation during pressure filtration, and improves the filtration effect; can realize that the multistage independently filters, the segmentation is anti-blasts etc. solid-liquid separation is thorough, can not produce and filter the short circuit problem. The filter screen subassembly adopts multilayer high strength sintering filter screen welded fastening on the metal support, then wholly fastens on the container chassis, and the material contact surface is the glossy top inoxidizing coating of 6 layers of metal sintering net, avoids the material to remain the problem. (3) automatic and complete discharging: the discharge port is arranged at the lowest position of the equipment, the material is automatically and completely discharged, and the general loose materials can be discharged without residue by combining the positive and negative rotation of internal stirring; (4) excellent drying effect: the spiral stirring of heating toper in the matching in the trinity desiccator, its polytropy design can let different characteristic materials all can reach the three-dimensional effect of turning of ideal, and the cover heat transfer that presss from both sides of equipment main part fully utilizes, and lets every partial material fully heat transfer all.

Above only the utility model discloses an it is preferred embodiment, the utility model discloses a scope of protection not only limits in above-mentioned embodiment, and the all belongs to the utility model discloses a technical scheme under the thinking all belongs to the utility model discloses a scope of protection. It should be noted that, for those skilled in the art, a plurality of modifications and decorations without departing from the principle of the present invention should be considered as the protection scope of the present invention.

Claims (7)

1. The utility model provides a solvent crystallization type bulk drug toper filtration washing desiccator, includes barrel (1) and lower cone (3), last barrel with lower cone from top to bottom can dismantle the connection, its characterized in that: the upper end of the upper barrel is provided with a seal head (2) connected with the upper barrel into a whole, the lower end of the lower cone is also provided with a bottom plate (6) connected with the lower cone into a whole, the outer wall of the upper barrel is fixed with a spiral first heating pipe (4), the outer wall of the lower cone is provided with a conical spiral second heating pipe (5), the cross sections of the first heating pipe and the second heating pipe are both in a semicircular shape, the lower end of the first heating pipe is communicated with the upper end of the second heating pipe, the upper end of the first heating pipe is connected with a heating medium inlet pipe (10), the lower end of the second heating pipe is connected with a heating medium outlet pipe (13), the outer side of the first heating pipe is provided with a first retainer Wen Zhaoti (14), and the first retainer Wen Zhaoti is fixed on the outer wall of the upper barrel, a second heat-insulating cover body (15) is also arranged on the outer side of the second heating pipe, the second heat-insulating cover body is fixed on the outer wall of the lower cone body, a first supporting seat (8) is respectively fixed on the outer walls of the two sides of the first heat-insulating cover body, the upper cylinder body is fixed on a support (7) through the first supporting seats of the two sides of the first heat-insulating cover body, the lower end of the upper cylinder body penetrates through the support and is connected with the lower cone body through a flange component, a plurality of upright posts (16) are further arranged at the bottom of the support, a lifting mechanism is further arranged between the lower cone body and the support, a straight section type filter (26) is arranged in the upper cylinder body, a conical filter (27) is arranged in the lower cone body, and the lower end of the straight section type filter is connected with the upper end of the conical filter, and a discharge valve (18) is arranged at the bottom of the bottom plate.

2. The solvent crystalline bulk drug tapered filtration washing dryer according to claim 1, characterized in that: the straight section formula filter be straight cylinder filter screen, the upper end of straight cylinder filter screen is fixed on the inner wall of last barrel through first metal-back (28), the conical filter is the sectional type filter, and it comprises first toper filter screen (27-1) and second toper filter screen (27-2), first toper filter screen with second toper filter screen from the top down set gradually in the lower cone, the upper end of first toper filter screen links to each other with the lower extreme of straight cylinder filter screen, the lower extreme of first toper filter screen is provided with second metal-back (30-1), the upper end of second toper filter screen is provided with third metal-back (30-2) that are connected with the second metal-back, be provided with on the inner wall of lower cone and be used for supporting second supporting seat (29) of fixed third metal-back, first toper filter screen with the cooperation of second toper filter screen through second metal-back and third metal-back and second supporting seat fix in the lower cone.

3. The solvent crystallization bulk drug tapered filtering washing dryer according to claim 2, characterized in that: first toper filter screen with the toper filtering component that second toper filter screen formed adopts multilayer high strength sintering filter screen welded fastening on the metal support, then whole fastening is on the container chassis, the material contact surface is the glossy top inoxidizing coating of 6 layers of metal sintering net, avoids the material to remain the problem.

4. The solvent crystalline bulk drug tapered filtration washing dryer according to claim 1, characterized in that: a double-internal heating helical ribbon stirrer is arranged in the upper cylinder body and the lower cone body, the double-internal heating helical ribbon stirrer is a variable pitch helical ribbon stirrer, which is composed of a rotating shaft (20), a spiral belt supporting rod and a stirring motor (23), the two spiral belts are spirally wound on the outer side of the rotating shaft in the lower cone, the upper end of the rotating shaft penetrates through the seal head and extends into a support frame (19), the support frame is fixed at the top of the seal head, the stirring motor is connected with a reduction gearbox, the reduction gearbox is detachably connected with the top of the support frame through a mounting plate (21), the rotating shaft is also connected with a transmission shaft through a coupler, the transmission shaft sequentially passes through the support frame and the reduction gearbox, the transmission shaft further passes through the reduction gearbox and the stirring motor, the stirring motor drives the transmission shaft to rotate, the two spiral belts are fixedly connected with the rotating shaft through a plurality of spiral belt supporting rods, the rotating shaft, the transmission shaft, the spiral belt and the spiral belt supporting rod are all hollow, the inner space of the spiral belt is communicated with the inner space of the rotating shaft through the inner space of the spiral belt supporting rod, one end of the transmission shaft extending out of the reduction gearbox is provided with a mechanical sealing structure rotating joint (24), the mechanical sealing structure rotary joint is respectively connected with the hot water pipeline and the cooling water pipeline, the mechanical sealing structure rotary joint is also connected with the hot water outlet pipe, the outer sides of the mechanical sealing structure rotary joint, the stirring motor and the reduction gearbox are also provided with a sealing cover body (22), the sealing cover body is detachably fixed on the mounting plate, and the hot water pipeline, the cooling water pipeline and the hot water outlet pipe respectively penetrate through the sealing cover body to be connected with the mechanical sealing structure rotary joint.

5. The solvent crystallization bulk drug tapered filtering washing dryer according to claim 1, characterized in that: the lower extreme outside of first heat preservation Wen Zhaoti is provided with first pipeline flange, first pipeline flange stretches into and is linked together with first heating pipe in the first heat preservation cover body, the upper end outside of the second heat preservation cover body is provided with second pipeline flange, second pipeline flange stretches into and is linked together with the second heating pipe in the second heat preservation cover body, first pipeline flange pass through U type connecting tube with second pipeline flange link to each other.

6. The solvent crystalline bulk drug tapered filtration washing dryer according to claim 1, characterized in that: the lifting mechanism comprises a servo motor (12), a lead screw (11) and a flexible connector, wherein the servo motor is fixed at the upper end of a lower vertebral body through a mounting seat, the lead screw is vertically arranged, the lower end of the lead screw is connected with the servo motor, the upper end of the lead screw penetrates through a support, and the support is connected onto the lead screw through the flexible connector.

7. The solvent crystallization bulk drug tapered filtering washing dryer according to claim 1, characterized in that: the bottom plate is also provided with a plunger type sampling valve, and the top of the seal head is also provided with a dust catcher (25).

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