CN217717185U - Blood sample diluting device for immunoassay detection equipment - Google Patents

Blood sample diluting device for immunoassay detection equipment Download PDF

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Publication number
CN217717185U
CN217717185U CN202221597094.1U CN202221597094U CN217717185U CN 217717185 U CN217717185 U CN 217717185U CN 202221597094 U CN202221597094 U CN 202221597094U CN 217717185 U CN217717185 U CN 217717185U
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frame
sampling
synchronous
mechanical arm
arm assembly
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李瑞庆
郭永峰
王陈
余占江
程小雷
陈旭
句江鹏
张少康
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Pro Med Beijing Technology Co ltd
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Pro Med Beijing Technology Co ltd
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Abstract

The utility model provides a blood sample diluting device for immunoassay detection equipment, belonging to the technical field of medical auxiliary equipment; the sampling module comprises a sampling assembly, an X-axis mechanical arm assembly, a Y-axis mechanical arm assembly and a Z-axis mechanical arm assembly, wherein the X-axis mechanical arm assembly, the Y-axis mechanical arm assembly and the Z-axis mechanical arm assembly can drive the sampling assembly to move in X, Y and Z directions; the consumable module is provided with an emergency treatment frame and a TIP discarding device. The utility model discloses can solve the human-computer interaction problem that doctor and machine placed at the sample, promote the instrument and use experience and feel and convenience, the consumptive material module has added the emergency call frame and has promoted the convenience that the instrument dealt with the emergency call condition, the TIP is abandoned the mouth and has adopted the design of gradual change opening to promote and abandon efficiency and the sampling module arm adopts guide rail and hold-in range motion mode to compare in traditional arm adoption splined shaft connection can lower cost realize the application of sample function, sampling assembly sets up the TIP head and has had or not the device to promote sampling efficiency and abandon efficiency.

Description

Blood sample diluting device for immunoassay detection equipment
Technical Field
The utility model relates to a medical treatment auxiliary equipment technical field, in particular to a blood specimen diluting device for immunoassay check out test set.
Background
Immunoassay is an analysis technique based on characteristic reactions of antigens and antibodies, and is mainly classified into radioimmunoassay, enzyme immunoassay, chemiluminescence immunoassay, fluorescence immunoassay, and the like according to different labeling techniques.
In the operation process of the existing immunoassay detection equipment, after a detection mode is set, the immunoassay detection equipment carries out detection analysis in the whole process according to a preset sequence, if an emergency blood sample needing urgent analysis exists, the immunoassay detection equipment can analyze the emergency blood sample only after the detection and analysis are finished, the immunoassay detection equipment is deficient in mobility and cannot deal with the emergency situation of emergency treatment, and the existing immunoassay detection equipment does not have an emergency frame. After the existing blood sampling frame is inserted into the sampling mixing module, the positioning between the blood sampling frame and the sampling mixing module can not be realized; the discarding device of the consumable module in the prior art usually adopts the design of a common notch, so that the phenomenon of blocking is easy to occur in the discarding process, and the consumable replacement efficiency is reduced.
In the operation process of the existing immunoassay detection equipment, after a detection mode is set, the immunoassay detection equipment carries out detection analysis in the whole process according to a preset sequence, if an emergency blood sample needing urgent analysis exists, the immunoassay detection equipment can analyze the emergency blood sample after the detection analysis is finished, the immunoassay detection equipment is deficient in mobility and cannot cope with emergency situations of emergency treatment, and the existing immunoassay detection equipment does not have an emergency detection channel.
When a blood sample detection analyzer is used for detecting a blood sample, the blood sample needs to be transferred from one station to another station, for example, the sample in the sample plate assembly is conveyed to a detection assembly for detection, and after the detection is finished, the TIP head containing the sample is conveyed to a consumable automatic separation mechanism for realizing automatic separation; therefore, the driving mechanism is very important for immunoassay; the actuating mechanism that different immunoassay appearance used is different, and actuating mechanism can not realize generally, and current mode is artifical to adsorb the blood sample to the reaction carrier through the instrument and reacts, needs artifical manually operation, and the blood sample volume of absorption is not controlled well, needs absorb many times, and efficiency is lower.
When blood sample analysis is carried out, the blood sample needs to be sucked and then transferred to a detection assembly for blood sample detection and analysis, the blood sample is generally transferred by TIP, and after the blood sample is transferred to the detection assembly for detection, the TIP head needs to be manually removed, so that the operation is inconvenient; therefore, a mechanism for automatically releasing the consumable material is needed.
SUMMERY OF THE UTILITY MODEL
The to-be-solved technical problem of the utility model is to provide a blood specimen diluting device for immunoassay check out test set can break away from and abandon the collection utensil automatically after can automizing absorption sample mixing and mixing are accomplished in order to solve the poor, inconvenient and the inconvenient problem of sampling of equipment emergency call mobility, equipment usage, has improved the work efficiency of equipment.
In order to solve the technical problem, the utility model provides a following technical scheme:
a blood sample diluting device for immunoassay detection equipment comprises a sampling module, a consumable module and a sample module, wherein the sampling module comprises a sampling assembly, an X-axis mechanical arm assembly, a Y-axis mechanical arm assembly and a Z-axis mechanical arm assembly, and the X-axis mechanical arm assembly, the Y-axis mechanical arm assembly and the Z-axis mechanical arm assembly can drive the sampling assembly to move in the X direction, the Y direction and the Z direction;
the sample module comprises a support plate, wherein a guide rail groove is formed in the support plate, a blood sampling frame and a diluent frame are inserted into the guide rail groove, and an opening structure is formed in the insertion position of the guide rail groove; the back of the supporting plate is provided with a back plate, the back plate is provided with a collision bead, the tail ends of the blood sampling frame and the diluent frame are respectively provided with a collision bead groove, and the rear side of the blood sampling frame is provided with a first sensor;
the consumable module comprises a consumable body, an emergency treatment frame and a TIP discarding device are arranged on the side face of the consumable body, a TIP discarding nozzle on the TIP discarding device is of a gradual change type structure, and the upper part of the emergency treatment frame is of a notch type structure and is subjected to reducing treatment;
the sampling assembly comprises a needle head which can pick up or discard the TIP head and a TIP head sensor which can detect whether the TIP head is arranged on the needle head or not;
the TIP discarding nozzle of the gradual change type structure comprises a large-diameter part and a small-diameter part, and the large-diameter part and the small-diameter part are in transition communication;
the blood sampling frame and the diluent frame are both provided with a push handle, and the bottom of the push handle is provided with an inward concave type curved surface structure.
Preferably, the X-axis mechanical arm assembly comprises a first rack, a fourth motor is installed at the bottom of the first rack, two first synchronous pulleys are installed at the top of the first rack, the fourth motor drives one of the first synchronous pulleys to rotate, a fourth synchronous belt is installed on the two first synchronous pulleys, a first synchronous sliding block is installed on the fourth synchronous belt, a first guide rail and a second guide rail are arranged at the top of the first rack, a fourth sliding block is installed on the first guide rail and the second guide rail, and the Y-axis mechanical arm assembly is installed on the fourth sliding block and the first synchronous sliding block.
Preferably, the Y-axis robot arm assembly comprises a second frame mounted on the first and fourth synchronization sliders; the Z-axis mechanical arm assembly is characterized in that two second synchronous belt wheels are arranged on the front side face of the second rack, a fifth motor is arranged on the rear side face of the second rack, the fifth motor drives one of the second synchronous belt wheels, fifth synchronous belts are installed on the two second synchronous belt wheels, a third guide rail is arranged on the front side face of the second rack, second synchronous sliding blocks are installed on the fifth synchronous belts and the third guide rail, and the Z-axis mechanical arm assembly is installed on the second synchronous sliding blocks.
Preferably, the Z-axis robot arm assembly comprises a third frame mounted on a second synchronization slide; be provided with the sixth motor on two third synchronous pulleys, the trailing flank on the leading flank of third frame, sixth motor drive one of them third synchronous pulley is two install the sixth hold-in range on the third synchronous pulley be provided with the fourth guide rail on the leading flank of third frame the sixth hold-in range with install the third synchronous slide block on the fourth guide rail install on the third synchronous slide block the sampling subassembly.
Preferably, the sampling assembly comprises a connecting shaft, the connecting shaft is connected with a connecting block, a connecting small block is fixed on the connecting block, a TIP head is fixed on the connecting small block, the connecting small shaft is connected with the connecting block, a small spring sleeve is sleeved on the connecting small shaft, a sleeve is connected with the connecting small shaft, a lower shell cover and a middle shell cover are arranged together with an upper shell cover from bottom to top and cover other components except the sleeve, a needle head and the connecting small shaft, and the needle head is arranged together with the connecting small shaft.
Preferably, a TIP head support plate and a mixing disc are arranged at the top of the consumable body, and a TIP head disc is arranged above the TIP head support plate.
Preferably, two clamping pieces are respectively placed on two sides of the TIP head disc, the clamping pieces are of two-section bending structures, and the two sides simultaneously clamp the TIP head support plate inwards to complete the fixation of the TIP head support plate and the TIP head disc.
Preferably, a blood collection tube mounting unit is arranged on the blood collection frame, and the blood collection tube mounting unit is of an open structure.
Compared with the prior art, the utility model, following beneficial effect has at least:
among the above-mentioned scheme, a sample module that is arranged in immunoassay check out test set's blood specimen diluting device adopts the guide rail pull design can solve doctor and machine at the human-computer interaction problem that the sample was placed, has promoted the experience sense and the convenience that the instrument used, and the design of guide rail makes blood sampling frame pull more convenient, and the consumptive material module has added the emergency call frame and has promoted the convenience that the instrument dealt with the emergency call condition and TIP abandons the mouth and adopts the design of gradual change opening to promote and abandon efficiency.
The utility model changes the connection mode of the transmission spline shaft of the mechanical arm, thereby realizing the sample adding function of the mechanical arm of the analytical instrument in a more stable motion mode of the guide rail and the synchronous belt with lower cost; the utility model discloses the sampling subassembly has added the TIP and has had the device can be more high-efficient automatic existence that detects sampling utensil TIP, has avoided the trouble of artifical change, just the utility model discloses a sampling subassembly TIP head can break away from the sampling subassembly automatically and increased abandon efficiency.
Drawings
The accompanying drawings, which are incorporated herein and form a part of the specification, illustrate embodiments of the present disclosure and, together with the description, further serve to explain the principles of the disclosure and to enable a person skilled in the pertinent art to make and use the disclosure.
FIG. 1 is a schematic structural view of an immunoassay test device of the present invention;
FIG. 2 is a schematic structural diagram of a sampling and mixing module of the immunoassay test device of the present invention;
FIG. 3 is a first schematic structural diagram of a cartridge clip module of the immunoassay detection apparatus of the present invention;
FIG. 4 is a schematic structural diagram of a card pushing mechanism and an incubation module of the immunoassay detection device of the present invention;
FIG. 5 is a schematic view of the optoelectronic data acquisition module of the immunoassay test device of the present invention;
FIG. 6 is a schematic structural view of a sampling module of the immunoassay testing device of the present invention;
FIG. 7 is a schematic structural diagram of an emergency detection module of the immunoassay detection device of the present invention;
FIG. 8 is a schematic structural view of a blood collecting rack and a diluent rack of the immunoassay testing device of the present invention;
FIG. 9 is a schematic structural view of a support plate of a sample module of the immunoassay test device of the present invention;
FIG. 10 is a schematic view of the bead-on-bead connection of the sample module of the immunoassay test device of the present invention;
fig. 11 is a schematic view of a first sensor of a sample module of the immunoassay test device of the present invention;
FIG. 12 is a schematic structural view of a consumable module of the immunoassay detection device of the present invention;
FIG. 13 is a schematic view of an emergency treatment device of a consumable module of the immunoassay test device of the present invention;
FIG. 14 is a schematic structural view of a TIP disposal nozzle of a consumable module of the immunoassay test device of the present invention;
FIG. 15 is a first schematic structural view of a clamping piece of a consumable module of the immunoassay detection apparatus of the present invention;
FIG. 16 is a second schematic structural view of the clamping piece of the consumable module of the immunoassay detection apparatus of the present invention;
FIG. 17 is a schematic structural view of a lower cover of a reagent kit of the immunoassay detection device of the present invention;
FIG. 18 is a detailed schematic view of FIG. 17;
FIG. 19 is a schematic structural view of the upper cover of the reagent kit of the immunoassay detection device of the present invention;
FIG. 20 is a schematic view of a reagent card of the immunoassay test device of the present invention;
FIG. 21 is a schematic view of the structure of the reagent kit of the immunoassay detection device of the present invention;
FIG. 22 is a second schematic structural view of a cartridge clip module of the immunoassay detection apparatus of the present invention;
fig. 23 is an exploded view of the cartridge clip module of the immunoassay test device of the present invention;
FIG. 24 is a schematic view of the structure of the reagent card outlet of the reagent cartridge of the immunoassay testing device of the present invention;
FIG. 25 is a schematic structural view of a turntable base of the immunoassay detection apparatus of the present invention;
fig. 26 is an exploded view of a first card pushing mechanism of the immunoassay test device of the present invention;
fig. 27 is an exploded view of a second card pushing mechanism of the immunoassay test device of the present invention;
FIG. 28 is an exploded view of a third card pushing mechanism of the immunoassay test device of the present invention;
fig. 29 is a schematic structural view of a stopper mechanism of a third card pushing mechanism of the immunoassay detection apparatus of the present invention;
FIG. 30 is a top view of the immunoassay test device of the present invention with the cartridge module removed;
fig. 31 is a first schematic structural diagram of a third card pushing mechanism and a third card pushing mechanism stopper of the immunoassay detection device of the present invention;
fig. 32 is a second schematic structural view of a third card pushing mechanism and a stop block of the third card pushing mechanism of the immunoassay detection device of the present invention;
fig. 33 is a schematic structural view of an X-axis mechanical arm assembly of the immunoassay detection apparatus of the present invention;
FIG. 34 is a schematic structural view of a Y-axis manipulator assembly of the immunoassay test device of the present invention;
FIG. 35 is a schematic structural view of a Z-axis manipulator assembly of the immunoassay test device of the present invention;
fig. 36 is a schematic structural view of a sampling assembly of the immunoassay testing device of the present invention;
FIG. 37 is an exploded view of a sampling assembly of the immunoassay test device of the present invention;
FIG. 38 is a second exploded view of the sampling assembly of the immunoassay test device of the present invention;
FIG. 39 is a schematic view of the sampling assembly of the immunoassay test device of the present invention sucking the TIP head;
FIG. 40 is a schematic view of the immunoassay test device of the present invention;
FIG. 41 is a flow chart of the collective detection of the immunoassay detection device of the present invention;
fig. 42 is a flow chart of the emergency detection of the immunoassay detection device of the present invention.
[ reference numerals ]
1. A base plate; 2. a sample module; 3. a consumable module; 4. a cartridge clip module; 5. an incubation module; 6. a photoelectric data acquisition module; 7. a sampling module; 8. an emergency detection module;
1. 21, a blood collection rack; 22. a diluent rack; 23. a support plate; 24. a blood collection rack guide rail; 25. a diluent rack guide rail; 28. a groove; 29. bumping beads; 30. a bead collision frame; 211. a first sensor;
31. an emergency treatment frame; 32. TIP head disk; 33. uniformly mixing the materials; 34. a TIP header; 35. TIP discard mouth; 36. A blood collection tube; 370. a clamping piece; 38. a TIP head support plate; 39. a graded structure; 40. a bending structure; 301. a gap type structure;
41. a cartridge clip support plate; 42. small magnet; 43. a kit; 431. a small magnet; 432. a lower cover of the kit; 433. covering the kit; 434. a slot position; 435. a first guide table; 436. a second guide table; 437. a reagent card outlet structure baffle; 44. a cartridge clip baffle; 45. a reagent card; 451. a guide groove; 411. chamfering; 461. The clip baffle plate gap structure; 46. a kit channel;
51. an upper heat preservation cover; 52. a lower heat preservation cover; 53. a rotary power module; 54. a second sensor; 55. a turntable; 56. tabletting; 571. connecting the main shaft; 572. expanding and tightening the sleeve; 573. a turntable synchronous large belt wheel; 574. a turntable synchronous small belt wheel; 575. a turntable motor; 576. a turntable synchronous belt; 577. a motor mounting seat;
11. a first card pushing mechanism; 111. a first motor; 112. a first synchronous belt mechanism; 113 small push block one; 114. the first card pushing seat; 115. the first card pushing seat is arranged below the first card pushing seat; 116. a first pinion plate; 117. a first small torsion spring; 118. a first plug screw; 119. a first slider; 12. a second card pushing mechanism; 121. a second motor; 122. a second synchronous belt mechanism; 123. a small push block II; 124. the second card pushing seat; 125. the second card pushing seat is arranged below the first card pushing seat; 126. a second pinion plate; 127. a second small torsion spring; 128. a second plug screw; 129. A second slider; 13. a third card pushing mechanism; 131. a third motor; 132. a third synchronous belt mechanism; 133. A third small push block; 134. the third card pushing seat; 135. the third card pushing seat is arranged below the second card pushing seat; 136. a third pinion rack; 137. A third small torsion spring; 138. thirdly, screwing; 139. a third slider; 48. a top block; 49. a cam block; 483. a fourth spring; 183. a stopper; 184. a pin; 185. sweeping the wharf; 484. an inductor;
61. a light emitting box; 62. tabletting the reagent card; 17. an X-axis robot arm assembly; 171. a fourth motor; 172. A fourth synchronous belt; 173. a first guide rail; 174. a second guide rail; 175. a first timing pulley; 27. a Y-axis robot arm assembly; 271. a fifth motor; 272. a fifth synchronous belt; 273. a third guide rail; 274. a second timing pulley; 37. a Z-axis robotic arm assembly; 371. a sixth motor; 372. a sixth synchronous belt; 373. a fourth guide rail; 374. a third synchronous pulley; 47. a sampling assembly; 178. a syringe assembly;
471. an upper housing shell; 472. a middle housing cover; 473. a lower shell cover; 474. a sleeve; 475. a small spring; 476. A needle head; 477. whether a sensor exists in the TIP head or not; 478. a connecting shaft; 479. connecting blocks; 480. connecting the small blocks; 481. connecting the small shaft;
100. a housing; 101. a display screen; 102. and (4) a cabin door.
As shown, specific structures and devices are labeled in the drawings for the purpose of clearly realizing the structure of the embodiments of the present invention, but this is only for illustrative purposes and is not intended to limit the present invention to the specific structures, devices and environments, and those skilled in the art can adjust or modify the devices and environments according to specific needs, and the adjustment or modification is still included in the scope of the appended claims.
Detailed Description
The blood sample diluting device for immunoassay test equipment provided by the present invention is described in detail below with reference to the accompanying drawings and specific embodiments. Meanwhile, it is described herein that the following embodiments are the best and preferred embodiments for the purpose of making the embodiments more detailed, and may be implemented in other alternative ways by those skilled in the art; also, the accompanying drawings are included to describe embodiments in greater detail and are not intended to limit the invention in any way.
It should be noted that references in the specification to "one embodiment," "an example embodiment," "some embodiments," etc., indicate that the embodiment described may include a particular feature, structure, or characteristic, but every embodiment may not necessarily include the particular feature, structure, or characteristic. Further, when a particular feature, structure, or characteristic is described in connection with an embodiment, it is submitted that it is within the knowledge of one skilled in the relevant art to effect such feature, structure, or characteristic in connection with other embodiments whether or not explicitly described.
In general, terms may be understood, at least in part, from their use in context. For example, the term "one or more" as used herein may be used to describe any feature, structure, or characteristic in the singular or may be used to describe a combination of features, structures, or characteristics in the plural, depending, at least in part, on the context. Additionally, the term "based on" may be understood as not necessarily intended to convey an exclusive set of factors, but may instead allow for the presence of other factors not necessarily explicitly described, depending at least in part on the context.
As used herein, the term "nominal" refers to a desired or target value, and a range above and/or below the desired value, of a characteristic or parameter set during a design phase of a production or manufacturing process for a component or process operation. The range of values may be due to slight variations in manufacturing processes or tolerances. As used herein, the term "about" indicates a value of a given amount that may vary based on the particular technology node associated with the subject semiconductor device. The term "about" may indicate a given amount of a value that varies, for example, within 5% -15% of the value (e.g., ± 5%, ± 10% or ± 15% of the value), based on the particular technology node.
It is understood that the meaning of "on 8230; \8230on," \8230, above "and" on 82308230; \823030, above "in the present disclosure should be interpreted in the broadest manner such that" on 8230; \8230above "means not only" directly on "something" but also on "something with the meaning of intervening features or layers therebetween, and" on 8230; \8230on "or" on 8230, above "not only means" on "or" above "something, but also may include the meaning thereof" on "or" above "something with no intervening features or layers therebetween.
Furthermore, spatially relative terms such as "below 823030; below", "lower", "above", "upper" and the like may be used herein for ease of description to describe one element or feature's relationship to another element or feature or features, as illustrated in the figures. Spatially relative terms are intended to encompass different orientations in use or operation of the device in addition to the orientation depicted in the figures. The device may be otherwise oriented and the spatially relative descriptors used herein interpreted accordingly.
As shown in fig. 1, the embodiment of the utility model provides an immunoassay detection device, including bottom plate 1, install sample module 2, consumptive material module 3, cartridge clip module 4, hatch module 5, photoelectric data acquisition module 6, sampling module 7 and emergency call detection module 8 on the bottom plate 1.
As shown in fig. 2, 8-11, the sample module 2 includes a support plate 23, the support plate 23 is mounted on the base plate 1, and the blood collection racks 21 and the diluent racks 22 are mounted on the support plate 23, preferably four rows of the blood collection racks 21 and one row of the diluent racks 22 are mounted. Five corresponding guide rail grooves are distributed on the support plate 23, namely four blood collecting rack guide rails 24 and one diluent rack guide rail 25, and the blood collecting rack 21 and the diluent rack 22 are respectively arranged on the blood collecting rack guide rails 24 and the diluent rack guide rails 25 in a drawing manner. Specifically, the insertion part of the guide rail groove is provided with an opening structure to form a size gradually changing form, the size is gradually reduced from large to small, the guide rail groove has a guiding function, correspondingly, the bottoms of the blood collection frame 21 and the diluent frame 22 are respectively provided with a guide block, the guide blocks can be inserted into the guide rail groove, the shape of the guide blocks is matched with the shape of the guide rail groove, and the insertion part of the guide blocks is also provided with an opening structure to form a size gradually changing form, the size is gradually reduced from small to large, the blood collection frame 21 and the diluent frame 22 can be smoothly drawn and inserted, and the blood collection frame 21 can be conveniently inserted into the corresponding guide rail groove; the back plate is installed at the back of the supporting plate 23 through screws, the side plates are installed on the left and the right through screws respectively, the bead collision frame 30 is arranged on the back plate, the tail ends of the blood sampling frame 21 and the diluent frame 22 are provided with the groove 28, the groove 28 is embedded with the collision bead 29 on the bead collision frame 30, the diluent frame 22 and the back plate are located, the blood sampling frame 21 and the back plate are located, the collision bead fixing and guide rail extracting design improves convenience and structure compactness, the design solves the problem of human-computer interaction of a doctor and a machine in sample placement, and the experience of instrument use is improved. A first sensor 211 is arranged on a rear baffle plate at the position of the blood sampling frame 21, and after the first sensor 211 detects that the blood sampling frame 21 is inserted into the guide rail groove, a code scanner arranged on the bottom plate 1 automatically records one-dimensional code information on the blood sampling frame 21, thereby judging the detection sample position and the patient information of the blood sampling frame 21.
The blood sampling frame 21 and the diluent frame 22 are both provided with a pushing handle, and the bottom of the pushing handle is provided with an inward concave curved surface structure which is convenient to take; be equipped with heparin tube installation unit on the blood sampling frame 21, heparin tube installation unit is open type structure, easy to assemble heparin tube 36 to, can follow the one-dimensional sign indicating number information of its opening part discernment heparin tube 36.
As shown in fig. 2, 12-16, the consumable module 3 comprises a consumable body, a TIP head support plate 38 and a blending plate 33 are arranged on the top of the consumable body, an emergency stand 31 and a TIP discarding device are arranged on the side surface of the consumable body, and a TIP head plate 32 is fixed on the TIP head support plate 38 through a clamping piece 370; the emergency treatment frame 31 is arranged close to the side wall of the sample module 2, the upper part of the emergency treatment frame 31 adopts an opening structure 301 and reducing treatment, and the emergency treatment frame has a guiding function for placing the blood collection tube 36 to the emergency treatment frame 31; a TIP discarding device is arranged beside the emergency frame 31, a TIP discarding nozzle 35 is arranged on the TIP discarding device, the TIP discarding nozzle 35 adopts a gradual change type structure 39, and the TIP head 34 is convenient to replace as the TIP head gradually changes from small to large from the TIP head insertion position to the TIP nozzle discarding port; the clamping pieces 370 adopt two sections of bending structures 40, one clamping piece 370 is respectively placed on each of two sides of the TIP head disc 32, the two sides simultaneously clamp the TIP head supporting plate 38 inwards to finish the fixation of the TIP head supporting plate 38 and the TIP head disc 32, and the clamping effect can be realized when the TIP head disc 32 is replaced; the TIP head disk 32 is provided with a plurality of TIP head 34 placing positions, the mixing disk 33 is arranged beside the TIP head disk 32, the sampling module 7 can replace the TIP head 34 through the TIP discarding nozzle 35, and the sampling module 7 can sequentially add samples in the blood sampling rack 21 and diluent in the diluent rack 22 into the mixing disk 33 to be mixed uniformly. TIP abandons mouth 35 and has adopted the design of gradual change formula opening to promote the efficiency that the consumptive material was changed, and emergency call frame 31 adopts the design of opening formula structure 301 to promote the convenience that the instrument dealt with the emergency call condition, and the bending structure 40 of clamping piece 370 has promoted the overall stability of TIP head dish 32 on consumptive material module 3. A waste box is arranged below the TIP discarding nozzle 35, and the used TIP head 34 directly falls into the waste box below from the TIP discarding nozzle 35.
As shown in fig. 3, 17-24, a cartridge clip module 4 is disposed right above the card pushing mechanism of the bottom plate 1, the cartridge clip module 4 includes a cartridge clip support plate 41, a plurality of cartridge clip baffles 44 are disposed on the cartridge clip support plate 41, a corresponding reagent box channel 46 is formed between two cartridge clip baffles 44, and a plurality of reagent boxes 43 vertically disposed are inserted into the corresponding reagent box channel 46. Be equipped with cartridge clip baffle opening structure 461 on the cartridge clip baffle 44, during every kit 43 inserted cartridge clip baffle 44 from cartridge clip baffle opening structure 461, be equipped with two little magnet stones 42 from top to bottom between two cartridge clip baffles 44, two upper and lower little magnet 431 on little magnet stone 42 and the kit 43 attract each other to accomplish fixedly, the guide problem of kit 43 has been solved in this kind of design, the convenience of changing kit 43 has been promoted and the accuracy difficult problem of having solved kit 43 location has promoted the convenience and the stability of the change kit 43 of instrument.
As shown in fig. 17-24, the reagent kit 43 includes a reagent kit upper cover 433 and a reagent kit lower cover 432, a slot 434 for placing the small magnet 431 is formed in the reagent kit lower cover 432, the small magnet 431 is placed in the slot 434, a first guide table 435 is formed in the reagent kit lower cover 432, a second guide table 436 is formed in the reagent kit upper cover 433, and the two guide tables are matched with each other; the first guide table 435 is a convex rib and is arranged on the side surface of the lower kit cover 432, and the middle of the second guide table 436 is provided with a convex rib which is arranged in the middle of the inner part of the upper kit cover 433; the reagent card 45 is arranged in the reagent box 43, the front side and the side edge of the reagent card 45 are respectively provided with a guide groove 451, the guide groove 451 at the front side is matched with a convex rib in the middle of the second guide table 436, and the guide groove 451 at the side edge is matched with the first guide table 435, so that the function of sliding the reagent card 45 in the reagent box 43 from top to bottom is realized, and the side turning can be prevented; the reagent box lower cover 432 is provided with a slot 434, the corresponding position of the reagent box upper cover 433 is provided with a buckle, the reagent box lower cover 432 and the reagent box upper cover 433 are buckled together through the slot 434 and the buckle, and a complete reagent box 43 is combined. A reagent card outlet structure is arranged at one corner opposite to the first 435 guide table at the lower end of the reagent kit 43, the reagent card outlet structure comprises a torsion spring and a reagent card outlet structure blocking piece 437 connected with the torsion spring, a notch is formed in the lower end of the reagent card 45, the first card pushing mechanism 11 pushes the reagent card 45 at the notch, the reagent card 45 props against the reagent card outlet structure blocking piece 437, and the torsion spring is forced to drive the reagent card outlet structure blocking piece 437 to rotate and move away, so that the reagent card 45 is pushed into the rotary table 55 by the first card pushing mechanism 11.
As shown in fig. 22, the clip retainer 44 and the clip support plate 41 are respectively provided with a chamfer 411, which can guide the reagent cartridge 43 and facilitate insertion.
As shown in fig. 4, 25-29, the incubation module 5 includes an upper heat-preservation cover 51, a lower heat-preservation cover 52, a rotary power module 53 and a second sensor 54, the second sensor 54 is disposed on the upper heat-preservation cover 51, the rotary power module 53 is disposed below the heat-preservation cover, and includes a turntable 55 and a turntable motor 575; the second sensor 54 is used to detect the absence of a reagent card 45 at the current location, preventing the presence of a reagent card 45 at this point when the blended sample is added.
A card pushing mechanism is arranged on the corresponding bottom plate 1 below the incubation module 5, and is respectively a first card pushing mechanism 11, a second card pushing mechanism 12 and a third card pushing mechanism 13; a pressing sheet 56 is arranged on the turntable 55, a connecting main shaft 571 is connected below the turntable 55, a bearing sleeve is connected below the bottom plate 1, the connecting main shaft 571 is fixed on a bearing, a bearing inner ring is installed and connected with the main shaft 571, and a bearing outer ring is installed in the bearing sleeve; a large turntable synchronous belt pulley 573 and an expansion sleeve 572 are sequentially mounted on the connecting main shaft 571, a motor mounting seat 577 is mounted on the base plate 1, a turntable motor 575 is mounted on the motor mounting seat 577, a small turntable synchronous belt pulley 574 is mounted on an output shaft of the turntable motor 575, and a turntable synchronous belt 576 is mounted on the large turntable synchronous belt pulley 573 and the small turntable synchronous belt pulley 574. The turntable motor 575 drives the turntable 55 to rotate through the turntable synchronous belt 576.
As shown in fig. 1, 4, 26 and 30, the bottom plate 1 is provided with 4 first card pushing mechanisms 11 corresponding to the reagent kit channels 46, the reagent kit channels 46 are provided with 4 first card pushing mechanisms 11 corresponding to the reagent kit channels, the top of the bottom plate 1 is provided with a first synchronous belt mechanism 112, the bottom of the bottom plate 1 is provided with a first motor 111 capable of driving the first synchronous belt mechanism 112, the synchronous belt of the first synchronous belt mechanism 112 is provided with the first card pushing mechanisms 11, specifically, the first slide block 119 is mounted on the synchronous belt, and the first slide block 119 can move along with the synchronous belt.
The first card pushing mechanism 11 comprises a first small pushing block 113, a first card pushing seat upper 114, a first card pushing seat lower 115, a first pinion plate 116, a first small torsion spring 117 and a first plug screw 118, wherein the first small torsion spring 117 is sleeved on the first plug screw 118, the first small pushing block 113 is installed on the first card pushing seat upper 114 through the first plug screw 118 and the first small torsion spring 117, the first card pushing seat lower 115 is installed on the first sliding block 119, the first card pushing seat upper 114 is installed above the first card pushing seat lower 115, the first pinion plate 116 is installed on the first card pushing seat lower 115, and the first synchronous belt mechanism 112 drives the first sliding block 119 to perform reciprocating card pushing motion so as to drive the first small pushing block first 113 to perform reciprocating motion.
As shown in fig. 1, 4, 27 and 30, a second card pushing mechanism 12 is disposed on the bottom plate 1 at a side of the first card pushing mechanism 11, a second timing belt mechanism 122 is mounted on the top of the bottom plate 1, a second motor 121 capable of driving the second timing belt mechanism 122 is mounted on the bottom of the bottom plate 1, the second card pushing mechanism 12 is mounted on a timing belt of the second timing belt mechanism 122, specifically, a second slider 129 is mounted on the timing belt, and the second slider 129 can move along with the timing belt.
The second card pushing mechanism 12 includes a second small pushing block 123, a second card pushing seat upper 124, a second card pushing seat lower 125, a second pinion 126, a second small torsion spring 127, a second stopper screw 128, the second small torsion spring 127 is sleeved on the second stopper screw 128, the second small pushing block 123 is installed on the second card pushing seat upper 124 through the second stopper screw 128 and the second small torsion spring 127, the second card pushing seat lower 125 is installed on the second slider 129, the second card pushing seat upper 124 is installed above the second card pushing seat lower 125, the second pinion 126 is installed on the second card pushing seat lower 125, the second synchronous belt mechanism 122 drives the second slider 129 to perform reciprocating card pushing movement, and further drives the second small pushing block 123 to perform reciprocating movement.
As shown in fig. 1, 4, and 28 to 32, a third card pushing mechanism 13 is disposed on the bottom plate 1 near the sample module 2, a third timing belt mechanism 132 is mounted on the top of the bottom plate 1, a third motor 131 capable of driving the third timing belt mechanism 132 is mounted on the bottom of the bottom plate 1, the third card pushing mechanism 13 is mounted on a timing belt of the third timing belt mechanism 132, specifically, a third slider 139 is mounted on the timing belt, and the third slider 139 can move along the timing belt.
The third card pushing mechanism 13 comprises a small pushing block three 133, a third card pushing seat upper 134, a third card pushing seat lower 135, a third pinion plate 136, a third small torsion spring 137, a third stopper screw 138, a pushing block 48 and a cam block 49, the third small torsion spring 137 is sleeved on the third stopper screw 138, the small pushing block three 133 is installed on the third card pushing seat upper 134 through the third stopper screw 138 and the third small torsion spring 137, the cam block 49 is installed on the third card pushing seat upper 134, the third card pushing seat lower 135 is installed on the third sliding block 139, the third card pushing seat upper 134 is installed above the third card pushing seat lower 135, the third pinion plate 136 is installed on the third card pushing seat lower 135, and the third synchronous belt mechanism 132 drives the small pushing block three 133 to perform reciprocating card pushing motion.
As shown in fig. 30, the reagent cards 45 in the reagent cartridges 43 are pushed into the rotary table 55 from the card pushing paths by the first card pushing mechanism 11, the pressing sheet 56 presses the reagent cards 45 into the rotary table 55, the rotary table 55 rotates to the card ejecting path located at the outermost side of the apparatus beside the card pushing paths, and the second card pushing mechanism 12 pushes the reagent cards 45 out of the rotary table 55.
As shown in fig. 30 to 32, when an emergency treatment is required, the reagent card 45 is inserted into an emergency treatment detection channel in the emergency treatment detection module 8 beside the consumable module 3, the emergency treatment detection channel is provided with a top block 48, the top block 48 comprises a fourth spring 483, one end of the fourth spring 483 is mounted on the clip support plate 41, the other end is connected with a stopper 183, the bottom end of the stopper 183 is mounted with an L-shaped frame, and a pin 184 is mounted on the L-shaped frame. At the initial position of the ejector block 48, the stopper 183 stops the reagent card 45, the sensor 484 disposed on the clip support plate 41 senses the insertion of the reagent card 45, the third motor 131 starts to drive the third synchronous belt mechanism 132 to move, the cam block 49 on the third card pushing seat 134 on the third card pushing mechanism 13 moves along with the third slider 139 of the third card pushing mechanism 13, the pin 184 on the ejector block 48 is pushed, the fourth spring 483 is pressed, the pin 184 is pushed to drive the stopper 183 to move open, so that the reagent card 45 enters the card pushing channel of the third card pushing mechanism 13 from the channel of the emergency detection module 8, the third synchronous belt mechanism 132 continues to move, the small third pusher 133 of the third card pushing mechanism 13 pushes the reagent card 45 into the rotary table 55 under the driving force, the stopper 183 moves under the rebounding force of the fourth spring 483, the ejector block 48 returns to the initial position, the rotary power module 53 drives the rotary table 55 to rotate, the rotary table 55 rotates to the card withdrawing channel, and the second card pushing mechanism 12 pushes the reagent card 45 out of the rotary table 55. The second card pushing mechanism 12 pushes the incubated reagent card 45 into the waste card box.
As shown in fig. 5, the cartridge clip support plate 41 is provided with the photoelectric data acquisition module 6, the photoelectric data acquisition module 6 includes a light emitting box 61 and a reagent card pressing plate 62, before the second card pushing mechanism 12 pushes the card to the waste card box, the reagent card 45 passes through the photoelectric data acquisition module 6, the reagent card pressing plate 62 presses the reagent card 45, and the light emitting box 61 scans and acquires data on the reagent card 45.
As shown in fig. 6, 33-39, a sampling module 7 is provided behind the consumable module 3 on the base plate 1. The sampling module 7 comprises an X-axis mechanical arm assembly 17, a Y-axis mechanical arm assembly 27, a Z-axis mechanical arm assembly 37 and a sampling assembly 47, the sampling module 7 can move in a three-axis space, and the sampling assembly 47 of the sampling module 7 can suck and spit liquid. The X-axis robot arm assembly 17 includes a first frame, a fourth motor 171 is installed at the bottom of the first frame, two first synchronous pulleys 175 are installed at the top of the first frame, the fourth motor 171 drives one of the first synchronous pulleys 175 to rotate, fourth synchronous belts 172 are installed on the two first synchronous pulleys 175, a first synchronous slider is installed on the fourth synchronous belt 172, a first guide rail 173 and a second guide rail 174 are arranged at the top of the first frame, fourth sliders are installed on the first guide rail 173 and the second guide rail 174, and the fourth motor 171 drives the first synchronous pulleys 175 to move, so that the robot arm can move on the first guide rail 173 and the second guide rail 174. The X-axis mechanical arm assembly 17 adopts a mode of double guide rails and synchronous belts, so that the mechanical arm can run more stably in the X-axis direction.
The Y-axis mechanical arm assembly 27 comprises a second frame, the second frame is mounted on the first synchronous sliding block and the fourth sliding block, the fourth motor 171 is driven to drive the first synchronous belt pulley 175 to rotate, the fourth synchronous belt 172 moves while driving the second frame to move through the first synchronous sliding block, and the movement of the Y-axis mechanical arm assembly 27 in the X direction is realized.
The Y-axis robot assembly 27 further includes two second timing pulleys 274 disposed on the front side surface of the second frame, and a fifth motor 271 disposed on the rear side surface, the fifth motor 271 drives one of the second timing pulleys 274, a fifth timing belt 272 is mounted on the two second timing pulleys 274, a third guide 273 is disposed on the front side surface of the second frame, and second timing sliders are mounted on the fifth timing belt 272 and the third guide 273.
The Z-axis mechanical arm assembly 37 includes a third frame, the third frame is mounted on the second synchronous slide block, the fifth motor 271 drives the second synchronous belt wheel 274 to rotate, and the fifth synchronous belt 272 drives the third frame to move by driving the second synchronous slide block while moving, so as to realize the movement of the Z-axis mechanical arm assembly 37 in the Y direction.
The Z-axis robot assembly 37 further includes two third timing pulleys 374 disposed on the front side surface of the third frame, and a sixth motor 371 disposed on the rear side surface, wherein the sixth motor 371 drives one of the third timing pulleys 374, sixth timing belts 372 are mounted on the two third timing pulleys 374, a fourth guide rail 373 is disposed on the front side surface of the third frame, and third timing sliders are mounted on the sixth timing belts 372 and the fourth guide rail 373.
Sampling component 47 installs on third synchronous slide, and sixth hold-in range 372 drives third synchronous pulley 374 and rotates, and the removal of sixth hold-in range 372 drives sampling component 47 through driving third synchronous slide simultaneously, realizes sampling component 47 in the removal of Z direction, specifically, sampling component 47 passes through the connecting piece with third synchronous slide and is connected. An injector assembly 178 is arranged at the lower end of an X-axis mechanical arm assembly 17 of the sampling module 7, the injector assembly 178 can be used for sucking a sample, and the Y-axis mechanical arm assembly and the Z-axis mechanical arm assembly adopt a transmission mode of a guide rail and a synchronous belt to enable the mechanical arm to run more efficiently and stably on a Z axis.
As shown in fig. 36-39, the sampling assembly 47 includes an upper housing cover 471, a middle housing cover 472, a lower housing cover 473, a sleeve 474, a small spring 475, a needle 476, a TIP presence sensor 477, a connecting shaft 478, a connecting block 479, a connecting small block 480, a connecting small shaft 481, and a TIP head 34. The connecting shaft 478 is connected with the connecting block 479, the connecting small block 480 is fixed on the connecting block 479, the TIP head sensor 477 is fixed on the connecting small block 480, the connecting small shaft 481 is connected with the connecting block 479, the small spring 475 is sleeved on the connecting small shaft 481, the sleeve 474 is connected with the connecting small shaft 481, the lower shell 473 and the middle shell 472 are assembled with the upper shell 471 from bottom to top and cover other parts except the sleeve 474, the needle 476 and the connecting small shaft 481, and the needle 476 is assembled with the connecting small shaft 481.
The sampling module 47 is plugged into the TIP 34, the further TIP presence sensor 477 detects that the TIP 34 has been taken, the sampling module 47 goes to the sample module 2 to suck up the sample and diluent, move it to the mixing tray 33, mix it and add it to the reagent card 45 to be incubated. During the picking of the TIP 34 by the sampling assembly 47, the sampling assembly 47 is moved downward and the needle 476 is inserted into the TIP 34, whereupon the small spring 475 of the sampling assembly 47 contracts and the TIP 34 pick-up is complete and the TIP presence sensor 477 detects the TIP 34; the sampling assembly 47 moves upward, at which time the small spring 475 of the sampling assembly 47 resets, bringing the needle 476 back. After the uniform mixing is completed, in the process of discarding the TIP head 34, the sampling assembly 47 moves downwards, the TIP head 34 moves into the TIP discarding nozzle 35, at the moment, the TIP head 34 is located at the large-caliber position of the TIP discarding nozzle 35, the TIP head 34 moves into the small-caliber position of the TIP discarding nozzle 35 in the TIP discarding nozzle 35, in the process of moving the sampling assembly 47 upwards, the TIP head 34 is clamped in the small-caliber position of the TIP discarding nozzle 35, and the TIP head 34 discarding is completed. The needle 476 then moves upward to discard the TIP 34 through the TIP disposal nozzle 35 to complete replacement of the TIP 34, the TIP presence sensor 477 detects that the TIP 34 has been discarded, the spring 475 resets the sleeve 474, and the sampling assembly 47 can repeatedly aspirate and discharge fluid.
Upper casing cover 471, well casing cover 472, lower casing cover 473 adopt disconnect-type structural design, and the limit function to the sleeve is upper and lower has been realized in the time of easy to assemble, and sleeve 474's structural design, the more convenient realization detect the TIP head have or not function, and this structural design's advantage lies in that it has realized the function of sample subassembly 47 with clearer structure.
As shown in fig. 7 and fig. 32, an emergency detection module 8 is disposed beside the cartridge module 4 on the bottom plate 1, the reagent card 45 can be directly inserted from the emergency detection module 8, the scanning head 185 scans information of the reagent card 45, the sensor 484 disposed on the cartridge support plate 41 senses insertion of the reagent card 45, the third motor 131 starts to drive the third synchronous belt mechanism 132 to move, the cam block 49 on the third card pushing seat 134 on the third card pushing mechanism 13 moves along with the third slider 139 of the third card pushing mechanism 13, the pin 184 on the pushing block 48 and the fourth spring 483 are pressed, the pin 184 is pushed to drive the stopper 183 to move, so that the reagent card 45 enters the card pushing channel of the third card pushing mechanism 13 from the channel of the emergency detection module 8, the third synchronous belt mechanism 132 continues to rotate, the small pushing block 133 of the third card pushing mechanism 13 drives the reagent card 45 to push into the rotary table 55, the stopper 183 to move under the resilience of the fourth spring 483, the pushing block 48 returns to the initial position, the power module 53 rotates the rotary table 55 to drive the rotary table 55 to push the reagent card 45 into the rotary table 55 after incubation time of the second card collecting data of the second card, and push the reagent card 6 after incubation of the second card is completed.
As shown in fig. 40, the utility model discloses the outside is equipped with shell 100, is equipped with hatch door 102 on shell 100, and hatch door 102 is established in the outside of sample module 2 and consumptive material module 3, opens hatch door 102 and can change sample or TIP head disc 32 and mixing dish 33. The hatch door 102 top is equipped with display screen 101, display screen 101 and the first sensor 211 on the side shield behind blood sampling frame 21, photoelectric data acquisition module 6 electric connection, the one-dimensional code of detector scanning and the information that photoelectric data acquisition module 6 gathered can spread into the control system in display screen 101 in real time, can show sample information, position, kind, incubation time, the incubation category that can control on the display screen 101 interface, can divide into groups kind to incubate.
As shown in fig. 41, an immunoassay detection method, the method comprising the steps of:
s1, guide blocks of a blood sampling frame 21 and a diluent frame 22 in a sample module 2 are inserted into guide rail grooves in a support plate 23 in a sliding mode, and when a first sensor 211 mounted on a rear side baffle of the position of the blood sampling frame 21 senses the insertion of the blood sampling frame 21, a code scanner mounted on a bottom plate 1 automatically records one-dimensional code information on the blood sampling frame 21 so as to judge the detection sample position and patient information of the blood sampling frame 21.
S2, aligning the side edge guide groove 451 of the reagent card 45 with the protruding ribs of the two guide platforms, sequentially loading the reagent card 45 into the reagent box 43, and inserting the reagent box 43 into the reagent box channel 46 from the clip baffle notch structure 461 on the clip baffle 44 of the clip module 4.
S3, after the information of the detection items is recorded, the fourth motor 171 of the X-axis mechanical arm assembly 17 drives the first synchronous pulley 175 to move to drive the fourth slider and the first synchronous slider on the X-axis mechanical arm assembly 17 to move on the first guide rail 173 and the second guide rail 174, namely, the movement of the Y-axis mechanical arm assembly 27 on the X axis is realized, the fifth motor 271 of the Y-axis mechanical arm assembly 27 drives the second synchronous pulley 274 to move to drive the second synchronous slider on the Y-axis mechanical arm assembly 27 to move on the third guide rail 273, namely, the movement of the Z-axis mechanical arm assembly 37 on the Y axis is realized, the sixth motor 371 of the Z-axis mechanical arm assembly 37 drives the third synchronous pulley 374 to move to drive the third synchronous slider on the Z-axis mechanical arm assembly 37 to move on the fourth guide rail 373, namely, the up-and-down movement of the sampling assembly 47 on the Z axis is realized, the mechanical arm assembly moves on a three-dimensional space to drive the sampling assembly 47 to move to a preset position TIP head disk 32, the sampling assembly 47 moves downwards, the needle 476 is inserted into the TIP head 34, and at the moment, the small spring 475 of the time, the TIP head 34 is contracted, the TIP head 34 is provided with a sensor 477 for detecting no head 34; the sampling component 47 moves upwards, at this time, the small spring 475 of the sampling component 47 resets to drive the needle 476 to reset, the mechanical arm component drives the sampling component 47 to move to the position above the blood sampling frame 21 of the sample module 2, and the sixth motor 371 drives the third synchronous belt pulley 374 to move, so that the sampling component 47 moves downwards on the fourth guide rail 373 to suck a sample, and then moves to the position above the diluent frame 22 to suck diluent in the same action. The mechanical arm assembly drives the sampling assembly 47 to move above the blending tray 33 in the XY direction, and the Z-axis mechanical arm assembly 37 drives the sampling assembly 47 to move downwards, so that the sample and the diluent are blended on the blending tray 33.
S4, the reagent card 45 in the reagent kit 43 in the cartridge clip module 4 slides downwards along a guide table in the reagent kit 43 and enters a card pushing channel from a reagent card outlet structure, a first motor 111 of the first card pushing mechanism 11 drives a first synchronous belt mechanism 112 to drive a first sliding block 119 to perform reciprocating card pushing motion, so as to drive a first small pushing block 113 to perform reciprocating motion, and the first small pushing block 113 hooks a notch below the reagent card 45 to push the reagent card 45 to enter the turntable 55; at this time, the mechanical arm assembly of the sampling module 7 drives the sampling assembly 47 to suck the mixed sample, and moves the mixed sample to the reagent card 45 in the turntable 55 according to a predetermined direction, so as to add the mixed sample into the reagent card 45 for reaction.
S5, after the uniform mixing is completed, the mechanical arm assembly drives the sampling assembly 47 to move to the position above the discarding device of the consumable module 3 in the XY axis direction, the sampling assembly 47 moves downwards, the TIP head 34 moves into the TIP discarding nozzle 35, at the moment, the TIP head 34 is located at the large caliber position of the TIP discarding nozzle 35, the TIP head 34 moves in the TIP discarding nozzle 35 to the small caliber position of the TIP discarding nozzle 35, the sampling assembly 47 moves upwards, the TIP head 34 is clamped in the small caliber position of the TIP discarding nozzle 35, and the TIP head 34 is discarded. The needle 476 is then moved upwardly to discard the TIP head 34 through the TIP disposal nozzle 35 to complete replacement of the TIP head 34, the TIP head presence sensor 477 detects that the TIP head 34 has been disposed of, the spring 475 resets the sleeve 474, and the sampling assembly 47 can repeatedly draw and drain fluid.
S6, after the reaction is finished, the rotating disc 55 rotates to the card withdrawing channel, the second motor 121 in the second card pushing mechanism 12 installed on the bottom plate 1 drives the second synchronous belt mechanism 122 to move to drive the second sliding block 129 to carry out reciprocating card pushing movement, and further drives the second small pushing block 123 to carry out reciprocating movement, the second small pushing block 123 hooks a gap below the reagent card 45 to push the reagent card 45 into the photoelectric data acquisition module 6, the reagent card pressing sheet 62 of the photoelectric data acquisition module 6 on the clip supporting plate 41 presses the reagent card 45, the light-emitting box 61 carries out data acquisition and detection, after the detection is finished, the second motor 121 in the second card pushing mechanism 12 installed on the bottom plate 1 drives the second synchronous belt mechanism 122 to move to drive the second sliding block 129 to carry out reciprocating card pushing movement, and further drives the second small pushing block 123 to carry out reciprocating movement, and the second small pushing block 123 hooks a gap below the reagent card 45 to push the reagent card 45 out, and pushes the reagent card 45 out from the rotating disc 55 to a waste card box.
As shown in fig. 42, an emergency condition;
s11, placing the blood collection tube 36 into the emergency treatment rack 31, sucking the emergency treatment sample and the diluent by the sampling assembly 47, placing the emergency treatment sample and the diluent into the blending disc 33, blending uniformly, and inserting the reagent card 45 into a channel of the emergency treatment detection module 8.
S22, the sensor 484 disposed on the clip supporting plate 41 senses the insertion of the reagent card 45, the third motor 131 starts to drive the third synchronous belt mechanism 132 to move, the cam block 49 of the third card pushing seat 134 on the third card pushing mechanism 13 moves along with the third slider 139 of the third card pushing mechanism 13, the pin 184 on the ejector block 48 and the fourth spring 483 are pressed, the pin 184 is pushed to drive the stopper 183 to move away, so that the reagent card 45 enters the card pushing channel of the third card pushing mechanism 13 from the channel of the emergency detection module 8, the third synchronous belt mechanism 132 continues to rotate, the small ejector block 133 of the third card pushing mechanism 13 pushes the reagent card 45 into the rotating disc 55 under the driving of the small ejector block 133 to incubate, the stopper 183 moves under the rebound action of the fourth spring 483, the ejector block 48 returns to the initial position, the rotary power module 53 drives the rotating disc 55 to rotate, and the sampling module 7 adds the mixed sample of the emergency into the reagent card 45 to react.
S33, after the incubation time, the rotating disc 55 rotates to the card withdrawing channel, the second card pushing mechanism 12 pushes the reagent card 45 into the photoelectric data acquisition module 6, and after the photoelectric data acquisition module 6 acquires data and completes detection, the second card pushing mechanism 12 pushes the incubated reagent card 45 into a waste card box.
The utility model discloses the technological effect is, a sample module for among immunoassay check out test set's blood specimen diluting device adopts the design of guide rail pull can solve the human-computer interaction problem that doctor and machine placed at the sample, has promoted the experience sense and the convenience that the instrument used, and the design of guide rail makes blood sampling frame pull more convenient, and the consumptive material module has added the emergency call frame and has promoted the convenience that the instrument dealt with the emergency call condition and TIP abandons the mouth and adopts gradual change opening design to promote abandoning efficiency.
The utility model changes the connection mode of the transmission spline shaft of the mechanical arm, thereby realizing the sample adding function of the mechanical arm of the analytical instrument in a motion mode of a guide rail and a synchronous belt which is lower in cost and more stable; the utility model discloses the sampling subassembly has added the TIP and has had the existence that whether device can be more high-efficient automatic detects sampling utensil TIP, has avoided the trouble of artifical change, just the utility model discloses a sampling subassembly TIP head can break away from the sampling subassembly automatically and increased abandon efficiency.
The present invention covers any alternatives, modifications, equivalents, and alternatives falling within the spirit and scope of the invention. In the following description of the preferred embodiments of the present invention, specific details are set forth in order to provide a thorough understanding of the present invention, and it will be apparent to those skilled in the art that the present invention may be practiced without these specific details. In other instances, well-known methods, procedures, flows, components, circuits, and the like have not been described in detail as not to unnecessarily obscure aspects of the present invention.
The foregoing is only a preferred embodiment of the present invention, and it should be noted that, for those skilled in the art, a plurality of modifications and decorations can be made without departing from the principle of the present invention, and these modifications and decorations should also be regarded as the protection scope of the present invention.

Claims (8)

1. A blood sample diluting device for immunoassay detection equipment is characterized by comprising a sampling module, a consumable module and a sample module, wherein the sampling module comprises a sampling assembly, an X-axis mechanical arm assembly, a Y-axis mechanical arm assembly and a Z-axis mechanical arm assembly, and the X-axis mechanical arm assembly, the Y-axis mechanical arm assembly and the Z-axis mechanical arm assembly can drive the sampling assembly to move in the X direction, the Y direction and the Z direction;
the sample module comprises a support plate, wherein a guide rail groove is formed in the support plate, a blood sampling frame and a diluent frame are inserted into the guide rail groove, and an opening structure is formed in the insertion position of the guide rail groove; a back plate is arranged at the back of the supporting plate, a collision bead is arranged on the back plate, collision bead grooves are respectively arranged at the tail ends of the blood sampling frame and the diluent frame, and a first sensor is arranged at the rear side of the blood sampling frame;
the consumable module comprises a consumable body, an emergency treatment frame and a TIP discarding device are arranged on the side face of the consumable body, a TIP discarding nozzle on the TIP discarding device is of a gradual change type structure, and the upper part of the emergency treatment frame is of a notch type structure and is subjected to reducing treatment;
the sampling assembly comprises a needle head which can pick up or discard the TIP head and a TIP head sensor which can detect whether the TIP head is arranged on the needle head or not;
the TIP discarding nozzle of the gradual change type structure comprises a large-diameter part and a small-diameter part, and the large-diameter part and the small-diameter part are in transition communication;
the blood sampling frame and the diluent frame are both provided with a push handle, and the bottom of the push handle is provided with an inward concave type curved surface structure.
2. The blood sample diluting device for immunoassay detection equipment according to claim 1, wherein the X-axis mechanical arm assembly comprises a first frame, a fourth motor is installed at the bottom of the first frame, two first synchronous pulleys are installed at the top of the first frame, the fourth motor drives one of the first synchronous pulleys to rotate, fourth synchronous belts are installed on the two first synchronous pulleys, a first synchronous slider is installed on the fourth synchronous belts, a first guide rail and a second guide rail are arranged at the top of the first frame, fourth sliders are installed on the first guide rail and the second guide rail, and the Y-axis mechanical arm assembly is installed on the fourth slider and the first synchronous slider.
3. The blood sample dilution device for an immunoassay test apparatus according to claim 1, wherein the Y-axis robotic arm assembly includes a second frame mounted on the first and fourth synchronized slides; the Z-axis mechanical arm assembly is characterized in that two second synchronous belt wheels are arranged on the front side face of the second rack, a fifth motor is arranged on the rear side face of the second rack, the fifth motor drives one of the second synchronous belt wheels, fifth synchronous belts are installed on the two second synchronous belt wheels, a third guide rail is arranged on the front side face of the second rack, second synchronous sliding blocks are installed on the fifth synchronous belts and the third guide rail, and the Z-axis mechanical arm assembly is installed on the second synchronous sliding blocks.
4. The blood sample dilution device for an immunoassay test apparatus according to claim 1, wherein the Z-axis robotic arm assembly includes a third frame mounted on a second synchronized slide; be provided with the sixth motor on two third synchronous pulleys, the trailing flank on the leading flank of third frame, sixth motor drive one of them third synchronous pulley is two install the sixth hold-in range on the third synchronous pulley be provided with the fourth guide rail on the leading flank of third frame the sixth hold-in range with install the third synchronous slide block on the fourth guide rail install on the third synchronous slide block the sampling subassembly.
5. The blood sample diluting device for immunoassay testing device as defined in claim 1, wherein the sampling assembly comprises a connecting shaft, the connecting shaft is connected to a connecting block, a connecting small block is fixed to the connecting block, a TIP head with or without a sensor is fixed to the connecting small block, a connecting small shaft is connected to the connecting block, a small spring is sleeved on the connecting small shaft, a sleeve is connected to the connecting small shaft, a lower housing and a middle housing are assembled with an upper housing from bottom to top and cover the other components except the sleeve, the needle and the connecting small shaft, and the needle is assembled with the connecting small shaft.
6. The blood sample diluting device for the immunoassay detection apparatus according to claim 1, wherein a TIP head support plate and a mixing disk are provided on the top of the consumable body, and a TIP head disk is provided above the TIP head support plate.
7. The blood sample diluting device for immunoassay testing apparatus as set forth in claim 6, wherein a clamping piece is disposed on each side of said TIP head disk, said clamping piece having a two-segment bent structure, and both sides simultaneously clamping said TIP head support plate inward to complete the fixation of said TIP head support plate and said TIP head disk.
8. The blood sample diluting device for immunoassay test equipment as set forth in claim 1, wherein a blood collection tube mounting unit is provided on the blood collection holder, the blood collection tube mounting unit having an open structure.
CN202221597094.1U 2022-06-24 2022-06-24 Blood sample diluting device for immunoassay detection equipment Active CN217717185U (en)

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CN202221597094.1U CN217717185U (en) 2022-06-24 2022-06-24 Blood sample diluting device for immunoassay detection equipment

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202221597094.1U CN217717185U (en) 2022-06-24 2022-06-24 Blood sample diluting device for immunoassay detection equipment

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GR01 Patent grant