CN217638302U

CN217638302U - Electronic refrigeration carbon dioxide supercritical point drying instrument

Info

Publication number: CN217638302U
Application number: CN202123360239.4U
Authority: CN
Inventors: 陈延滨; 李伟; 王琪
Original assignee: Beijing Coriolis Scientific Instrument Co ltd
Current assignee: Beijing Coriolis Scientific Instrument Co ltd
Priority date: 2021-12-29
Filing date: 2021-12-29
Publication date: 2022-10-21
Anticipated expiration: 2031-12-29

Abstract

The utility model aims at providing a novel electronic refrigeration carbon dioxide supercritical point drying instrument, including drying instrument body and electron refrigeration piece (13), drying instrument body lateral wall closely posts electron refrigeration piece (13), and radiator (14) are closely posted in the electron refrigeration piece (13) outside, and fan (15) are installed in the radiator (14) outside. The utility model discloses an electron refrigeration carbon dioxide supercritical point desiccator has improved the cooling efficiency of test desiccator body, and the electron refrigeration piece can provide the heating simultaneously, does not need the heating rod, can easily realize surpassing and face the point to provide visual window, be convenient for observe liquid carbon dioxide liquid level, have magnetic stirring, improve replacement efficiency.

Description

Electronic refrigeration carbon dioxide supercritical point drying instrument

The technical field is as follows:

the utility model relates to a be used for drying biological sample under the continuous state of attitude, an electron refrigeration carbon dioxide supercritical point desiccator specifically says so. It can be widely applied to the field of biological drying.

Background

It is often necessary to dewater a biological sample, and there is continuity of the state of matter during the drying process, i.e. there is no significant difference between the liquid and gaseous states of the medium, and the surface stress at the interface is reduced to zero. This phenomenon occurs at a specific temperature and pressure, referred to as the critical point. The condition of zero surface stress can be used for drying biological samples, and the damage of the surface stress to the samples is avoided. If thermal drying or lyophilization is used, the liquid will transition between the gaseous and liquid states and surface stresses will develop at the interface, thereby destroying the biological sample. Therefore, in the bio-drying process, it is necessary to dry the sample in a critical state. The critical point of water is temperature +374 ℃ pressure 3212PSI, which is inconvenient and prone to thermal damage to the sample. The most convenient critical point drying medium is carbon dioxide, which has a critical point temperature of +31 ℃ and a pressure of 1072PSI. However, carbon dioxide does not mix readily with water and therefore a third medium, typically acetone, must be used as the intermediate liquid. The water in the biological sample is replaced by acetone, and then the acetone is replaced by carbon dioxide, so that the stress-free drying of the sample is realized.

Before using the critical point drying instrument, in order to fill liquid carbon dioxide, the drying instrument body must be cooled firstly, the traditional critical point drying instrument uses the liquid carbon dioxide to cool the drying instrument body, the liquid carbon dioxide is considered to be converted into a gas state to absorb heat, so that the drying instrument body is cooled, and in fact, the liquid carbon dioxide cannot be gasified at a fixed position and is generally gasified at a place with sudden pressure change, so that the drying instrument body is cooled slowly. The supercritical point must be achieved by heating using a heating rod, making the structure extremely complicated.

The utility model aims at providing a novel electronic refrigeration carbon dioxide supercritical point desiccator has improved the cooling efficiency of test desiccator body, and the electron refrigeration piece can provide the heating simultaneously, does not need the heating rod, can easily realize surpassing and face the point to provide visual window, be convenient for observe liquid carbon dioxide liquid level, have magnetic stirring, improve replacement efficiency.

SUMMERY OF THE UTILITY MODEL

In order to realize the utility model purpose, the utility model discloses a following technical scheme realizes:

the utility model relates to an electron refrigeration carbon dioxide supercritical point drying instrument, including drying instrument body and electron refrigeration piece 13, drying instrument body lateral wall closely posts electron refrigeration piece 13, and the electron refrigeration piece 13 outside closely posts radiator 14, and fan 15 is installed in the radiator 14 outside.

As above electron refrigeration carbon dioxide supercritical point desiccator, the desiccator body includes cavity 11, the 11 outer walls of cavity are equipped with visual window 3, visual window 3 passes through visual window gland 1 and installs on cavity 11, open on the visual window gland 1 has circular shape hole, with visual window 3 is concentric.

According to the electronic refrigeration carbon dioxide supercritical point dryer, the upper channel 2 and the lower channel 4 are arranged on the wall of the cavity 11, which faces the visible window 3, and the cavity 11, the upper channel 2, the lower channel 4 and the gap between the visible window 3 and the cavity 11 form a communicating vessel, so that the correct position of the liquid level of the liquid carbon dioxide and whether the liquid carbon dioxide is in a supercritical state can be conveniently observed.

In the electronic refrigeration carbon dioxide supercritical point dryer, the upper part of the cavity 11 is fixed with the upper cover 9 through the upper cover screw 8.

According to the electronic refrigeration carbon dioxide supercritical point dryer, the upper part of the cavity 11 is provided with the liquid inlet hole 10 for filling liquid carbon dioxide, and the lower part is provided with the liquid outlet 5.

According to the electronic refrigeration carbon dioxide supercritical point dryer, the magnetic stirrer 12 is arranged in the cavity 11, the motor 7 is arranged at the bottom of the cavity 11, and the magnet 6 is arranged on the motor 7.

In the above electronically-cooled carbon dioxide supercritical point dryer, the fan may be positioned perpendicular or parallel to the heat sink.

The utility model discloses profitable effect is: the cooling efficiency of test desicator body has been improved, and the electron refrigeration piece can provide the heating simultaneously, does not need the heating rod, can easily realize surpassing and face the point to provide visual window, be convenient for observe liquid carbon dioxide liquid level, have magnetic stirring, improve replacement efficiency.

Drawings

Fig. 1 is a schematic sectional view of the present invention.

Fig. 2 is a left side view.

In the figure: visual window gland 1, upper channel 2, visual window 3, lower passageway 4, tap hole 5, magnet 6, motor 7, upper cover screw 8, upper cover 9, feed liquor hole 10, cavity 11, magnetic stirrers 12, electron refrigeration piece 13, radiator 14, fan 15.

The specific implementation mode is as follows:

the electronic refrigeration carbon dioxide supercritical point drying instrument comprises a drying instrument body and an electronic refrigeration piece 13, wherein the electronic refrigeration piece 13 is tightly attached to the side wall of the drying instrument body, a radiator 14 is tightly attached to the outer side of the electronic refrigeration piece 13, and a fan 15 is installed on the outer side of the radiator 14. The electronic refrigeration sheet 13 is an electronic component which can refrigerate and heat simultaneously when direct current is introduced, the heat of the heating surface is continuously dissipated, the refrigeration surface can refrigerate continuously, and the refrigeration effect is determined by the temperature difference of the two surfaces. Therefore, the temperature of the cavity 11 can be suddenly reduced, and the refrigeration of the refrigeration piece with ideal effect can reach more than minus 10 degrees. The low temperature chamber 11 facilitates the filling of liquid carbon dioxide which cannot fill the chamber 11 if the temperature is above the critical point of carbon dioxide. The heat sink 14 has dense fins, and the fan 15 blows the fins on the heat sink 14 to achieve the heat dissipation effect, and the fan may be positioned perpendicular or parallel to the fins. When the electronic refrigeration sheet 13 is powered reversely, the heating function can be realized, and the fan 15 stops rotating.

The drying instrument body as shown in the figure comprises a cavity body 11, a visual window 3 is installed on the outer wall of the cavity body 11, the visual window 3 is installed on the cavity body 11 through a visual window gland 1, a circular hole is formed in the visual window gland 1 and is concentric with the visual window 3, an upper channel 2 and a lower channel 4 are formed in the wall, facing the visual window 3, of the cavity body 11, the cavity body 11 and the upper channel 2, the lower channel 4 and gaps between the visual window 3 and the cavity body 11 form communicating devices, and the correct position of the liquid carbon dioxide liquid level and whether the liquid carbon dioxide liquid level is in a supercritical state or not can be conveniently observed. At a temperature of about 30 c and a corresponding pressure of 1,100psi, the liquid carbon dioxide level disappears and reaches a critical point as observed through the viewing window 3. If cooling will result in a reappearance of the liquid carbon dioxide level, and if heating to about 30 degrees, the level will disappear again.

An upper cover 9 is fixed on the upper part of the cavity 11 through an upper cover screw 8 as shown in the figure.

As shown in the figure, the upper part of the cavity 11 is provided with a liquid inlet 10 for filling liquid carbon dioxide, and the lower part is provided with a liquid outlet 5 for discharging carbon dioxide or displaced acetone in the biological sample.

As shown in the figure, the magnetic stirrer 12 is arranged in the cavity 11, the motor 7 is arranged at the bottom of the cavity 11, the magnet 6 is arranged on the motor 7, and the motor 7 rotates to drive the magnet 6 to rotate, so that the magnetic stirrer 12 in the cavity 11 is driven to rotate to form magnetic stirring, and the replacement efficiency of acetone and carbon dioxide in a biological sample is improved.

To sum up, the utility model provides a novel electronic refrigeration carbon dioxide supercritical point drying instrument, it is not high to have solved traditional critical point drying instrument and have used liquid carbon dioxide to carry out cooling drying instrument body efficiency, uses the heating rod to heat and makes the problem that the structure is complicated.

Claims

1. An electronic refrigeration carbon dioxide supercritical point dryer comprises a dryer body, wherein the dryer body comprises a cavity (11), a visual window (3) is arranged on the outer wall of the cavity (11), the visual window (3) is installed on the cavity (11) through a visual window gland (1), and a circular hole is formed in the visual window gland (1) and is concentric with the visual window (3); an upper channel (2) and a lower channel (4) are formed in the wall, which faces the visual window (3), of the cavity (11), and the cavity (11), the upper channel (2), the lower channel (4) and gaps between the visual window (3) and the cavity (11) form communicating vessels, so that the correct position of the liquid carbon dioxide liquid level and whether the liquid carbon dioxide liquid level is in a supercritical state can be observed conveniently; the electronic refrigeration dryer is characterized by further comprising an electronic refrigeration sheet (13), wherein the electronic refrigeration sheet (13) is tightly attached to the side wall of the dryer body, a radiator (14) is tightly attached to the outer side of the electronic refrigeration sheet (13), and a fan (15) is installed on the outer side of the radiator (14).

2. The electronic refrigeration carbon dioxide supercritical point dryer according to claim 1, characterized in that the upper cover (9) is fixed on the upper part of the cavity (11) through an upper cover screw (8).

3. The electronic refrigeration carbon dioxide supercritical point dryer according to claim 1, characterized in that the cavity (11) is opened with a liquid inlet hole (10) for filling liquid carbon dioxide at the upper part and a liquid outlet (5) at the lower part.

4. The electronic refrigeration carbon dioxide supercritical point dryer according to claim 1, characterized in that a magnetic stirrer (12) is installed in the cavity (11), a motor (7) is installed at the bottom of the cavity (11), and a magnet (6) is installed on the motor (7).