CN217527533U - Micro-fluidic chip - Google Patents

Micro-fluidic chip Download PDF

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Publication number
CN217527533U
CN217527533U CN202220456597.0U CN202220456597U CN217527533U CN 217527533 U CN217527533 U CN 217527533U CN 202220456597 U CN202220456597 U CN 202220456597U CN 217527533 U CN217527533 U CN 217527533U
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China
Prior art keywords
plate body
switch
flow control
plate
control switch
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CN202220456597.0U
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Chinese (zh)
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付文成
纪文威
孙相鑫
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Yihong Shenzhen Gene Co ltd
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Yihong Shenzhen Gene Co ltd
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Abstract

The utility model provides a micro-fluidic chip, includes first plate body, second plate body, switch board and press device, is equipped with the runner groove of taking the breach on the first plate body, is equipped with the opening that corresponds with the breach position in runner groove on the second plate body, and the switch board is the material of easily deforming, and the laminating of second plate body and first plate body forms the miniflow channel of taking the breach, and the switch board forms the flow control switch in miniflow channel breach department with the laminating of first plate body, and press device is used for pressing the flow control switch. The pressing device presses the switch board to deform and attach the switch board to the first board body when pressing the flow control switch, so that the flow channel can be closed, after the flow control switch is loosened by the pressing device, the switch board automatically restores to the original position or the micro flow channel, when liquid flows through the closed flow control switch under physical pressure, the attached first board body and the switch board are flushed open, the flow channel switch restores to the open position, the control mode of the flow control switch is simple, multiple control from opening to closing or from closing to opening can be realized, and the use is convenient.

Description

Micro-fluidic chip
Technical Field
The application relates to the technical field of microfluid control, in particular to a microfluidic chip.
Background
Microfluidics (Microfluidics) refers to the science and technology involved in systems that process or manipulate tiny fluids using microchannels, and microfluidic devices are commonly referred to as microfluidic chips, also known as lab-on-a-chip.
The existing flow passages are formed by various schemes, such as a laser engraving method, an injection molding method, an ultrasonic welding method, an adhesive method and the like. The flow channel formed by the existing flow channel forming method is positioned in the microfluidic chip, so that the requirements on the production process are high, the yield is low, the production cost is high, the control of the flow control switch is complex, only single control from on to off or from off to on can be realized, and the use is inconvenient.
SUMMERY OF THE UTILITY MODEL
In order to solve the technical problem, the application provides a microfluidic chip.
According to a first aspect of the present application, there is provided in one embodiment a microfluidic chip comprising:
the first plate body is provided with a runner groove with a notch;
the second plate body is provided with an opening corresponding to the notch of the runner groove;
the second plate body is attached to the first plate body, and the second plate body and the flow channel groove are encircled to form a micro-flow channel with a gap;
the switch plate is made of an easily deformable material, the switch plate is attached to the first plate body, the switch plate and the first plate body are enclosed at a gap of the micro channel to form a flow control switch, and the flow control switch is communicated with the micro channel;
a pressing device for pressing the fluidic switch.
In one embodiment, the first plate is made of a hard material.
In one embodiment, the first plate and the runner groove are integrally formed.
In an embodiment, a manner of attaching the second board to the first board includes: ultrasonic welding, gluing, hot melt connection or threaded connection.
In one embodiment, the attaching manner of the switch board and the first board body includes: hot melt bonding or gluing.
In an embodiment, the second board body and the switch board are the same in quality, and the second board body and the switch board are of an integrally formed structure.
In one embodiment, the pressing device includes: a push rod; the push rod is used for pressing the flow control switch.
In one embodiment, a soft rubber sleeve is arranged at the front end of the push rod.
In one embodiment, the pressing device further comprises: a push rod motor; the push rod motor is used for driving the push rod to do linear motion.
In one embodiment, the push rod motor includes: the output motor, the speed reduction assembly, the drive screw and the drive nut, the both ends of speed reduction assembly respectively with the output shaft of output motor with drive screw is connected, drive screw with the drive nut cooperation, the drive nut with the push rod is connected.
According to the microfluidic chip of the embodiment, the first plate body is provided with the runner groove with the notch, the second plate body is attached to the first plate body and can be enclosed with the runner groove to form the micro-runner with the notch, the switch board at the notch of the micro-runner and the first plate body are enclosed to form the flow control switch, and the runner groove and the flow control switch are both arranged on the surface of the microfluidic chip, so that when the pressing device presses the flow control switch, the switch board is pressed to deform and is attached to the first plate body to complete the closing of the runner, after the pressing device releases the flow control switch, the switch board automatically returns to the original position or when liquid in the micro-runner flows through the closed flow control switch under physical pressure, the attached first plate body and the switch board are flushed open, the runner switch returns to the open position, the control mode of the flow control switch is simple, multiple times of control from open to close or from close to open can be realized, the use is convenient, the structures of the first plate body and the second plate are simple, the requirements on the production process are low, the yield is high, and the production cost is low.
Drawings
FIG. 1 is a schematic structural diagram of a microfluidic chip according to an embodiment;
fig. 2 is a schematic structural diagram of a first plate body of the microfluidic chip in one embodiment;
fig. 3 is an exploded view of a pressing device of a microfluidic chip according to an embodiment.
Description of the reference numerals: 1. a first plate body; 11. a runner groove; 12. a micro flow channel; 13. a current control switch; 2. a second plate body; 3. a pressing device; 31. a push rod; 32. a soft rubber sleeve; 33. a drive nut; 34. a drive screw; 35. a speed reduction assembly; 36. an output motor; 37. and (5) a bearing.
Detailed Description
The present application will be described in further detail with reference to the following detailed description and accompanying drawings. Wherein like elements in different embodiments have been given like element numbers associated therewith. In the following description, numerous details are set forth in order to provide a better understanding of the present application. However, those skilled in the art will readily recognize that some of the features may be omitted or replaced with other elements, materials, methods in different instances. In some instances, certain operations related to the present application have not been shown or described in detail in order to avoid obscuring the core of the present application from excessive description, and it is not necessary for those skilled in the art to describe these operations in detail, so that they may be fully understood from the description in the specification and the general knowledge in the art.
Furthermore, the features, operations, or characteristics described in the specification may be combined in any suitable manner to form various embodiments, and the operation steps involved in the embodiments may be interchanged or modified in order as will be apparent to those skilled in the art. Accordingly, the description and drawings are merely for clarity of description of certain embodiments and are not intended to necessarily constitute and/or sequence.
The numbering of the components as such, e.g., "first", "second", etc., is used herein only to distinguish the objects as described, and does not have any sequential or technical meaning. The term "connected" and "coupled" as used herein includes both direct and indirect connections (couplings), unless otherwise specified.
The micro-fluidic chip in the embodiment of the application, including first plate body, the second plate body, switch board and press device, be equipped with the runner groove of taking the breach on the first plate body, be equipped with the opening that corresponds with the breach position in runner groove on the second plate body, the switch board is easy deformable material, the laminating of second plate body and first plate body forms the miniflow channel of taking the breach, switch board and the laminating of first plate body form the flow control switch in miniflow channel breach department, press device is used for pressing the flow control switch. The flow control switch is pressed to deform the switch board and is attached to the first board body to complete the closing of the flow channel when the pressing device presses the flow control switch, after the flow control switch is loosened by the pressing device, the switch board automatically restores to the original position or liquid in the micro flow channel flows through the closed flow control switch under physical pressure to break the attached first board body and the switch board, the flow channel switch restores to the open position, the control mode of the flow control switch is simple, multiple times of control from opening to closing or from closing to opening can be realized, the use is convenient, the structures of the first board body and the second board body are simple, the requirements on the production process are low, the yield is high, and the production cost is low.
The present application is illustrated by the following specific examples.
The first embodiment is as follows:
as shown in fig. 1 to 3, an embodiment of the present application provides a microfluidic chip, including: a first plate body 1, a second plate body 2, a switch plate and a pressing device 3. The first plate body 1 is provided with a runner groove 11 with a notch. The second plate body 2 is provided with an opening corresponding to the notch position of the runner groove 11. The second plate body 2 is attached to the first plate body 1, and the second plate body 2 and the runner groove 11 enclose a micro-runner 12 with a gap. The switch board is made of a deformable material, the switch board is attached to the first board body 1, the switch board and the first board body 1 are enclosed at a notch of the micro-channel 12 to form a flow control switch 13, and the flow control switch 13 is communicated with the micro-channel 12 to prevent the micro-channel 12 from leaking pressure and water. The pressing device 3 is used for pressing the flow control switch 13, when the pressing device 3 presses the flow control switch 13, the switch board is pressed, deformed and attached to the first board body 1, the micro-channel 12 can be closed, after the pressing device 3 loosens the flow control switch 13, the switch board automatically restores to the original position, or when liquid in the micro-channel 12 flows through the closed flow control switch 13 under physical pressure, the attached first board body 1 and the switch board are separated, and the flow channel switch restores to the opening position. In this embodiment, the flow channel 11 is protruded from the surface of the first plate 1, the flow channel 11 is not disposed at the notch, when the second plate 2 is attached to the first plate 1, the flow channel 11 and the portion of the second plate 2 supported by the flow channel 11 enclose the micro flow channel 12, and the other portion of the second plate 2 is attached to the first plate 1, so that the formed micro flow channel 12 has good sealing performance, the switch board is attached to the first plate 1 at the notch of the micro flow channel 12, and both ends of the switch board can be attached to the flow channel 11, so that the formed flow control switch 13 is communicated with the micro flow channel 12, thereby preventing the micro flow channel 12 from leaking water. In some embodiments, the flow channel 11 is recessed in the first plate 1, a groove with the same depth as the flow channel 11 and a larger width is provided at the notch, when the second plate 2 is attached to the first plate 1, the flow channel 11 and the second plate 2 enclose the micro flow channel 12, the switch plate is attached to the first plate 1 at the notch of the micro flow channel 12, and the switch plate and the groove provided at the notch enclose the flow control switch 13.
In this embodiment, the first plate body 1 is made of a hard material, so that the first plate body 1 is prevented from being deformed greatly to affect the sealing effect of the micro flow channel 12 when the flow control switch 13 is pressed to be closed. In some embodiments, the first plate body 1 at the position of the flow control switch 13 is made of a deformable material, and the switch plate is made of a hard material, at this time, the pressing device 3 presses the first plate body 1 at the position of the flow control switch 13 to close the flow control switch 13.
In this embodiment, the first plate 1 and the runner groove 11 are integrally formed, and the structure is simple.
In this embodiment, the attaching mode of the second plate body 2 and the first plate body 1 includes: ultrasonic bonding, gluing, hot melt connection or threaded connection can select the laminating mode according to the material or the shape of first plate body 1 and second plate body 2.
In this embodiment, the laminating mode of switch board and first plate body 1 includes: hot melt is connected and is glued, can select the laminating mode according to the material or the shape of first plate body 1 and switch board.
In this embodiment, the second plate 2 and the switch board are made of the same material, the second plate 2 and the switch board are integrally formed, and when the second plate 2 is attached to the first plate 1, the micro channel 12 and the flow control switch 13 are formed, so as to reduce the number of processing steps, simplify the product structure, and reduce the production cost.
The pressing device 3 can press the flow control switch 13 by a mechanical pressing force, a local air pressure, a hydraulic pressure, an electromagnetic force, or the like, in this embodiment, the pressing device 3 includes a push rod 31, the position of the push rod 31 corresponds to the position of the flow control switch 13, and the push rod 31 is used for pressing the flow control switch 13.
In this embodiment, the front end of the push rod 31 is provided with the soft rubber sleeve 32, so that the push rod 31 is prevented from being in hard contact with the hard structure of the first plate body 1, and the product is prevented from being damaged, and meanwhile, the soft rubber sleeve 32 can deform to a certain extent when the flow control switch 13 is pressed, so that the switch board at the position of the flow control switch 13 can be attached to the first plate body 1 more closely, and the sealing effect when the flow control switch 13 is in the closed state is ensured.
In this embodiment, the pressing device 3 further includes a push rod motor, and the push rod motor is used for driving the push rod 31 to perform linear motion, so as to press the flow control switch 13.
In this embodiment, the push rod motor includes: the fluid control switch 13 is pressed or loosened by the drive nut 33, and in order to ensure the transmission effect of the drive screw 34, the bearing 37 is further arranged on the drive screw 34.
According to the microfluidic chip in the above embodiment, the microfluidic chip includes the first plate, the second plate, the switch board and the pressing device, the first plate is provided with the runner groove with the notch, the second plate is provided with the opening corresponding to the notch of the runner groove, the switch board is made of a deformable material, the second plate and the first plate are attached to form the microchannel with the notch, the switch board and the first plate are attached to form the fluidic switch at the notch of the microchannel, and the pressing device is used for pressing the fluidic switch. The flow control switch is pressed to deform the switch board and is attached to the first board body to complete the closing of the flow channel when the pressing device presses the flow control switch, after the flow control switch is loosened by the pressing device, the switch board automatically restores to the original position or liquid in the micro flow channel flows through the closed flow control switch under physical pressure to break the attached first board body and the switch board, the flow channel switch restores to the open position, the control mode of the flow control switch is simple, multiple times of control from opening to closing or from closing to opening can be realized, the use is convenient, the structures of the first board body and the second board body are simple, the requirements on the production process are low, the yield is high, and the production cost is low.
It is right to have used specific individual example above the utility model discloses expound, only be used for helping to understand the utility model discloses, not be used for the restriction the utility model discloses. To the technical personnel in the technical field of the utility model, the foundation the utility model discloses an idea can also be made a plurality of simple deductions, warp or replace.

Claims (10)

1. A microfluidic chip, comprising:
the first plate body is provided with a runner groove with a notch;
the second plate body is provided with an opening corresponding to the notch of the runner groove;
the second plate body is attached to the first plate body, and the second plate body and the flow channel are encircled to form a micro-flow channel with a gap;
the switch plate is made of an easily deformable material, the switch plate is attached to the first plate body, the switch plate and the first plate body are enclosed at a gap of the micro channel to form a flow control switch, and the flow control switch is communicated with the micro channel;
a pressing device for pressing the flow control switch.
2. The microfluidic chip of claim 1, wherein the first plate body is a hard material.
3. The microfluidic chip of claim 2, wherein the first plate body and the channel are integrally formed.
4. The microfluidic chip of claim 3, wherein the attaching of the second plate body to the first plate body comprises: ultrasonic welding, gluing, hot melt connection or threaded connection.
5. The microfluidic chip of claim 4, wherein the attaching of the switch plate to the first plate body comprises: hot melt bonding or gluing.
6. The microfluidic chip according to claim 5, wherein the second plate body is the same as the switch plate, and the second plate body and the switch plate are integrally formed.
7. The microfluidic chip according to any of claims 1 to 6, wherein the pressing means comprises: a push rod; the push rod is used for pressing the flow control switch.
8. The microfluidic chip according to claim 7, wherein the front end of the push rod is provided with a soft rubber sleeve.
9. The microfluidic chip of claim 8, wherein the pressing means further comprises: a push rod motor; the push rod motor is used for driving the push rod to do linear motion.
10. The microfluidic chip of claim 9, wherein the push rod motor comprises: the output motor, the speed reduction assembly, the drive screw and the drive nut, the both ends of speed reduction assembly respectively with the output shaft of output motor with drive screw is connected, drive screw with the drive nut cooperation, the drive nut with the push rod is connected.
CN202220456597.0U 2022-03-02 2022-03-02 Micro-fluidic chip Active CN217527533U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202220456597.0U CN217527533U (en) 2022-03-02 2022-03-02 Micro-fluidic chip

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202220456597.0U CN217527533U (en) 2022-03-02 2022-03-02 Micro-fluidic chip

Publications (1)

Publication Number Publication Date
CN217527533U true CN217527533U (en) 2022-10-04

Family

ID=83427199

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202220456597.0U Active CN217527533U (en) 2022-03-02 2022-03-02 Micro-fluidic chip

Country Status (1)

Country Link
CN (1) CN217527533U (en)

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