CN217365861U - Electrochemical sensor - Google Patents

Abstract

The utility model provides an electrochemical sensor, which comprises a basal body part and an electrode part; the utility model is used for bear the weight of the base member of electrode and set tubular structure into, electrode circumference distributes in the surface of tubulose base member. Compare with the electrochemical sensor that the slabby base member bore electrode material, the utility model discloses effectively reduced electrochemical sensor's size, made electrochemical sensor microminiaturization, reached the dimensional requirement that can with electrochemical sensor disect insertion human subcutaneous tissue. Meanwhile, the substrate with the cavity inside can also provide an injection window for a patient to receive drug treatment, so that the diagnosis and treatment procedures of diseases are simplified, and the electrochemical sensor has the double functions of detection of human physiological parameters and subcutaneous drug injection.

Description

Electrochemical sensor

Technical Field

The utility model relates to an electrochemistry technical field especially relates to an electrochemical sensor.

Background

With the development of interdisciplines in a new era, knowledge and technical methods among the disciplines are continuously fused, and scientific research and production application, as well as human life, are gradually and closely related. The cross of subject fields such as materials, physics, chemistry, biomedicine and the like shows good development activity and research potential in the fields such as environmental protection, biomedicine, national defense and military industry and the like. Especially, the sensor with good biocompatibility and sensitivity is widely applied to clinical medicine and disease detection.

In the prior art, the detection of the physiological parameters of the human body by the electrochemical sensor is helpful for medical staff to determine whether the patient needs to be treated by injection according to the detection result, for example, the patient needs to be injected with insulin due to overhigh blood sugar concentration. Real-time detection and treatment can better manage diabetes and reduce diabetic complications. However, due to the fact that the size of the electrochemical sensor is too large in the background of the prior art, the electrochemical sensor cannot directly act on subcutaneous tissues; the process of detecting the physiological parameters of the human body by the electrochemical sensor and the process of carrying out subcutaneous drug injection on the patient according to the detected parameters are two mutually independent processes and can be realized by two different devices. This is not conducive to resource conservation and the development of a rapid disease diagnosis and treatment fusion.

The biomedical detection aspect is not beneficial to the popularization of the electrochemical sensor in the biomedical field.

Therefore, there is a need for a micro electrochemical sensor that can simultaneously detect physiological parameters of a human body and inject subcutaneous drugs.

SUMMERY OF THE UTILITY MODEL

In order to solve the problem, the utility model provides an electrochemical sensor to solve current electrochemical sensor and can't have human physiological parameter's the detection concurrently and the problem of subcutaneous medicine injection function.

The utility model provides an electrochemical sensor, include: a substrate and an electrode;

the substrate is of a tubular structure;

the electrodes are circumferentially distributed on the outer surface of the base body;

wherein the electrode comprises: the electrode structure comprises a working electrode and a power supply electrode, wherein the working electrode and the power supply electrode are parallel to each other.

Optionally, one end of the electrode is connected with the electric signal output end through a lead; the electrochemical sensor further includes an insulating layer covering the wire.

Optionally, the length of the substrate is 5mm-1 cm;

the inner diameter of the matrix is 100-500 μm;

the preparation materials of the matrix are as follows: any one of PET, PVC, FR4, polyurethane, silk fibroin, chitosan, polylactic acid, polyvinyl chloride and polyimide.

Optionally, the length of the electrode is 4mm-8 mm.

Optionally, the electrode is prepared by a screen printing technology or a micro-nano processing technology.

Optionally, the power supply electrode is: an active electrode.

Optionally, the working electrode is an Ag/AgCl electrode.

Optionally, the power supply electrode comprises: a counter electrode and a reference electrode.

Optionally, the counter electrode is a gold material, a platinum material or a composite material electrode composed of a carbon material and an electron mediator;

the reference electrode is an Ag/AgCl electrode.

Optionally, the working electrode is a composite electrode composed of a gold material, a platinum material or a carbon material and an electron mediator.

Has the advantages that:

the utility model provides an electrochemical sensor compares with the electrochemical sensor who has now to bear electrode material with the plate-shaped base member, the utility model discloses a set up working electrode and power electrode at the basal body surface of tubular structure, effectively reduced electrochemical sensor's size, make electrochemical sensor miniaturation, reach the dimensional requirement that can be with electrochemical sensor disect insertion human subcutaneous tissue, realize human physiological parameter's detection. Meanwhile, medical personnel utilize the utility model provides an electrochemical sensor obtains human physiological parameter to when carrying out the analysis and confirming this patient needs the medicine injection treatment to human physiological parameter, the base member that has the tubular structure can also act as the injection window of disease treatment, and medical personnel directly get into human subcutaneous tissue with the medicine injection through the base member of tubular structure, realize detecting and treating dual purpose.

In addition, the working electrode and the power electrode of the miniature electrochemical sensor are both prepared on the surface of the tubular matrix through a screen printing technology or a micro-nano processing technology, so that the size of the electrode can be flexibly controlled, and the miniaturization of the electrochemical sensor is facilitated.

Drawings

In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the drawings required to be used in the description of the embodiments of the present invention will be briefly introduced below, and it is obvious that the drawings in the following description are only some embodiments of the present invention, and for those skilled in the art, other drawings can be obtained according to these drawings without inventive labor.

FIG. 1 is a schematic diagram illustrating a substrate structure of an electrochemical sensor provided in an embodiment of the present application;

FIG. 2 illustrates a side view of an electrochemical sensor provided by an embodiment of the present application;

FIG. 3 illustrates a side view of an electrochemical sensor provided by an embodiment of the present application;

FIG. 4 illustrates a side view of an electrochemical sensor provided by an embodiment of the present application;

FIG. 5 illustrates a side view of an electrochemical sensor provided by an embodiment of the present application.

Detailed Description

The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are some, not all embodiments of the present invention. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative efforts belong to the protection scope of the present invention.

In the description of the present invention, it should be noted that the terms "upper", "lower", "inner", "outer", "front end", "rear end", "both ends", "one end", "the other end" and the like indicate orientations or positional relationships based on the orientations or positional relationships shown in the drawings, and are only for convenience of description and simplification of description, but do not indicate or imply that the device or element to which the reference is made must have a specific orientation, be constructed in a specific orientation, and be operated, and thus, should not be construed as limiting the present invention. Furthermore, the terms "first" and "second" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance.

In the description of the present invention, it is to be noted that, unless otherwise explicitly specified or limited, the terms "mounted," "disposed," "connected," and the like are to be construed broadly, and for example, "connected" may be either fixedly connected or detachably connected, or integrally connected; can be mechanically or electrically connected; they may be connected directly or indirectly through intervening media, or they may be interconnected between two elements. The specific meaning of the above terms in the present invention can be understood in specific cases to those skilled in the art.

As shown in fig. 1-3, the present invention provides an electrochemical sensor, comprising a substrate 1 and an electrode 2; the substrate 1 is a tubular structure with a cavity, and the outer surface of the substrate 1 is used for bearing an electrode; as the substrate 1 bearing the electrodes 2 is arranged into a tubular structure, and the electrodes 2 are circumferentially distributed on the outer surface of the tubular substrate 1, compared with the electrochemical sensor with the plate-shaped substrate 1 bearing electrode materials, the size of the electrochemical sensor is effectively reduced, the electrochemical sensor is miniaturized, and the size requirement that the electrochemical sensor can be directly inserted into subcutaneous tissues of a human body is met. Meanwhile, the substrate 1 with the cavity inside can provide an injection window for a patient to receive drug treatment, so that the diagnosis and treatment procedures of diseases are simplified, and the electrochemical sensor has the double functions of detection of human physiological parameters and subcutaneous drug injection.

Specifically, in the electrochemical sensor, the substrate 1 has a structure as shown in fig. 1, and the substrate 1 has a tubular structure having a cavity.

In some embodiments, the material for preparing the substrate 1 may be any one of PET, PVC, FR4, polyurethane, silk fibroin, chitosan, polylactic acid, polyvinyl chloride and polyimide.

In some embodiments, the length of the tubular structural matrix 1 may be 5mm to 1cm and the inner diameter of the tubular structural matrix 1 may be 100 μm to 500 μm to meet the injection requirements.

Specifically, the structure is shown in a side view of an electrochemical sensor shown in fig. 2, in the electrochemical sensor, electrodes 2 are distributed in parallel on the circumference of a substrate 1, the electrodes 2 may include a working electrode 2-1 and a power supply electrode 2-2, and one end of each electrode 2 is connected with an electrical signal output end 4 through a lead 3; in the embodiment, no specific requirement is made on the circumferential arrangement of the working electrode 2-1 and the power supply electrode 2-2 on the outer surface of the tubular base body 1, that is, the working electrode 2-1 and the power supply electrode 2-2 may be uniformly arranged at circumferential intervals or randomly arranged in the circumferential direction, so that the parallel arrangement between the electrodes is satisfied.

In some embodiments, the power supply electrode 2-2 may have two of the following; in the first case, the power electrode 2-2 may be an active electrode 2-2-3, and FIG. 3 shows a side view of an electrochemical sensor having a working electrode 2-1 and an active electrode 2-2-3, wherein the active electrode 2-2-3 may function to both connect a circuit and stabilize a voltage, and the active electrode 2-2-3 may be an Ag/AgCl electrode. At the moment, the action electrode 2-2-3 and the working electrode 2-1 are distributed in parallel in the circumferential direction of the matrix 1, and the detection ends of the electrodes are positioned on the same straight line.

In the second case, the power electrode 2-2 may include two electrodes, which are a counter electrode 2-2-1 and a reference electrode 2-2-2, respectively, and fig. 4 shows a side view of an electrochemical sensor having a working electrode 2-1, a counter electrode 2-2-1 and a reference electrode 2-2-2, wherein the counter electrode 2-2-1 functions to communicate with a circuit, the reference electrode 2-2-2 functions to stabilize a voltage, and the counter electrode 2-2-1 may be the same as the working electrode 2-1 and is a composite electrode composed of gold material, platinum material or carbon material and an electronic mediator; the reference electrode 2-2-2 can be the same as the action electrode 2-2-3, and is an Ag/AgCl electrode. At the moment, the reference electrode 2-2-2, the counter electrode 2-2-1 and the working electrode 2-1 are distributed in parallel in the circumferential direction of the matrix 1, and the detection ends of the electrodes are on the same straight line.

The printing technology or the micro-nano processing technology can reduce the size of the electrode to the micron level, so the screen printing technology or the micro-nano processing technology can be selected to prepare the specific electrode.

In some embodiments, the length of the electrode 2 may be set to 3mm to 8 mm.

In some embodiments, working electrode 2-1 may be: a composite material electrode composed of a gold material, a platinum material or a carbon material and an electron mediator.

Specifically, among the above-mentioned electrochemical sensor, electrochemical sensor still includes insulating layer 5, and fig. 5 shows the side view of electrochemical sensor in an embodiment of the present invention, insulating layer 5 structure is as shown in fig. 5, and insulating layer 5 sets up on the base member to cover wire 3 between electrode 2 and the signal of telecommunication output 4, in order to avoid producing the risk of electric leakage when testing.

In some embodiments, the length of the detection end of the exposed electrode after being covered by the insulating layer may be 4mm to 8 mm.

It should be noted that fig. 5 is only a schematic diagram of a side view structure of the electrochemical sensor, and in practical applications, the thicknesses of the electrode 2, the substrate 1 and the insulating layer 5 are all in the nanometer-micrometer range, so that in practice, the insulating layer 5 is tightly attached to the substrate 1 to avoid the problem of electric leakage caused by conductive exposure.

The embodiments in the present specification are all described in a progressive manner, and each embodiment focuses on differences from other embodiments, and portions that are the same and similar between the embodiments may be referred to each other.

While preferred embodiments of the present application have been described, additional variations and modifications of these embodiments may occur to those skilled in the art once they learn of the basic inventive concepts. Therefore, it is intended that the appended claims be interpreted as including the preferred embodiment and all such alterations and modifications as fall within the true scope of the embodiments of the application.

The principle and the implementation of the present application are explained herein by applying specific examples, and the above description of the embodiments is only used to help understand the method and the core idea of the present application; meanwhile, for a person skilled in the art, according to the idea of the present application, there may be variations in the specific embodiments and the application scope, and in summary, the content of the present specification should not be construed as a limitation to the present application.

Claims (9)

1. An electrochemical sensor, characterized by comprising a substrate (1) and an electrode (2);

the substrate (1) is of a tubular structure;

the electrodes (2) are circumferentially distributed on the outer surface of the base body (1);

wherein the electrode (2) comprises: the electrode assembly comprises a working electrode (2-1) and a power supply electrode (2-2), wherein the working electrode (2-1) and the power supply electrode (2-2) are parallel to each other.

2. Electrochemical sensor according to claim 1, characterized in that one end of the electrode (2) is connected to an electrical signal output (4) via a wire (3); the electrochemical sensor further comprises an insulating layer (5), the insulating layer (5) covering the wire (3).

3. Electrochemical sensor according to claim 1, characterized in that the length of the substrate (1) is 5mm-1 cm;

the inner diameter of the matrix (1) is 100-500 μm;

the preparation materials of the matrix (1) are as follows: any one of PET, PVC, FR4, polyurethane, silk fibroin, chitosan, polylactic acid, polyvinyl chloride and polyimide.

4. Electrochemical sensor according to claim 1, characterized in that the length of the electrode (2) is 4-8 mm.

5. Electrochemical sensor according to claim 1, characterized in that the electrodes (2) are prepared by screen printing techniques or micro-nano machining techniques.

6. Electrochemical sensor according to claim 1, characterized in that the power supply electrodes (2-2) are: and an action electrode (2-2-3).

7. Electrochemical sensor according to claim 6, characterized in that the active electrode (2-2-3) is an Ag/AgCl electrode.

8. Electrochemical sensor according to claim 1, characterized in that the power supply electrode (2-2) comprises: a counter electrode (2-2-1) and a reference electrode (2-2-2).

9. The electrochemical sensor of claim 8,

the reference electrode (2-2-2) is an Ag/AgCl electrode.

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