CN216484800U - Solid phase extraction instrument - Google Patents
Solid phase extraction instrument Download PDFInfo
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- CN216484800U CN216484800U CN202122303333.XU CN202122303333U CN216484800U CN 216484800 U CN216484800 U CN 216484800U CN 202122303333 U CN202122303333 U CN 202122303333U CN 216484800 U CN216484800 U CN 216484800U
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Abstract
The utility model discloses a solid phase extraction instrument, which comprises a host and a solvent barrel lowest liquid level detection system, wherein the host comprises a shell, a plurality of extraction units and a public liquid adding unit, the extraction units and the public liquid adding unit are positioned in the shell, the structure of each extraction unit is the same, and each extraction unit is sequentially arranged from bottom to top: the purification column, the purification column rotating manipulator and the tetrafluoro cock of the purification column are clamped together, meanwhile, the purification column fixing clamp fixes the glass tube, and the receiving cup device is placed at the lower part of a liquid outlet of the purification column; the common charging unit comprises: metering pump, multi-channel switching valve, liquid-feeding waste liquid bottle and liquid-feeding driving device. The solid phase extraction apparatus improves the accuracy and the working efficiency of the experiment, integrates activation, balance, sample loading, cleaning, dehydration, drying and elution, can be widely applied to sample analysis and experiments of food, medicines, environmental samples and the like, and is particularly suitable for the purification process of detecting samples of semi-volatile organic compounds, petroleum hydrocarbons and the like.
Description
Technical Field
The utility model relates to the technical field of extraction instruments, in particular to a solid phase extraction instrument.
Background
At present, there is not the automatic solid phase extraction experimental apparatus of purifying the material from filling, and many analysis laboratories are the simple and easy experimental apparatus of building temporarily in addition, and occupation space is big, and degree of automation is low, and the operation is inconvenient, from causing experimental work efficiency low.
For example, in the case of the shimadzu ASPE900 full-automatic solid phase extractor, the commercial purification column can be used only once, and there are problems that the volume is too small to meet the experimental requirements of some dirty samples, the filling material with sufficient quality is not filled, the solution still has residual color after the purification is completed, and the flow rate of the receiving solution cannot be adjusted.
Therefore, the utility model aims to overcome the defects of the structure and invents an integrated solid phase extractor which has small volume and high automation degree and can be suitable for a self-filling purification column.
Aiming at the problems, innovative design is urgently needed on the basis of the structure of the original extraction instrument.
Disclosure of Invention
The utility model aims to provide a solid phase extraction instrument, which aims to solve the problems that the solid phase extraction instrument can only be used once, has too small volume to meet the experimental requirements of part of dirty samples, can not be filled with fillers with enough quality, has residual color of a solution after purification and the like, and can not adjust the flow rate of a receiving solution, which are proposed in the background art.
In order to achieve the purpose, the utility model provides the following technical scheme: the utility model provides a solid phase extraction appearance, includes the host computer, and the minimum liquid level detecting system of solvent bucket, host computer include casing, public liquid feeding unit and be located the inside a plurality of extraction units of casing, and the structure of every extraction unit is the same, and every extraction unit is from supreme being in proper order down: the purification column, the purification column on-site detection device, the purification column liquid level sensor adjusting device, the purification column rotating mechanical arm and a tetrafluoro cock of the purification column are clamped together, meanwhile, the purification column fixing clamp fixes the glass tube, and the receiving cup device is placed at the lower part of a liquid outlet of the purification column.
And a display control device is arranged on one side of the outer surface of the shell, and the display control device is electrically connected with the purification column rotating mechanical arm, the metering pump, the multi-channel switching valve, the liquid feeding transmission device, the solvent barrel liquid level sensor, the purification column on-site detection device, the purification column liquid level sensor adjusting device and the like.
Solvent bucket minimum liquid level detection system, including solvent bucket, solvent bucket level sensor, solvent bucket set casing, wherein solvent bucket level sensor is connected with the host computer, is responsible for when the experiment begins whether detecting the solvent bucket is on the throne and whether the solution liquid level arrives minimum liquid level, is less than minimum liquid level when the solution liquid level, and the instrument is reported to the police and is reminded the timely liquid feeding of staff.
Preferably, the public liquid adding unit comprises a polytetrafluoroethylene pipeline, a metering pump, a multi-channel switching valve, a liquid adding waste liquid bottle and a liquid adding transmission device, the multi-channel switching valve is used for selecting a solvent to be added, the pipeline needs to empty waste liquid generated when the instrument initially works and waste liquid generated when different solvents are switched and added are all discharged into the liquid adding waste liquid bottle, and the liquid adding transmission device ensures that a solvent filling port moves to the position above the purifying column to be filled
Preferably, the flow path of the multi-channel switching valve and the flow path of the metering pump are both made of polytetrafluoroethylene materials, and the pipeline is also made of polytetrafluoroethylene materials, so that liquid cannot be polluted; the metering pump provides guarantee for accurately filling the solvent; the multi-channel switching valve provides guarantee for selecting which solvent to fill.
The purification column consists of a glass tube with a tetrafluoro cock of the purification column, a filler and medical absorbent cotton, and the purification column consists of the glass tube with the tetrafluoro cock, the filler and the medical absorbent cotton;
preferably, the purification column rotating manipulator consists of a stepping speed reduction motor and a plug chuck. The tetrafluoro cock of the purifying column can be rotated at the precision of 0.1 degree/step, and the effects of switching on and off the purifying column and adjusting the flow rate of the received liquid are achieved.
A stepping speed reducing motor and a cock chuck form a rotary manipulator of the purifying column.
Preferably, the cup receiving device consists of a liquid receiving bottle, a waste liquid receiving bottle and a sliding rail. When receiving waste liquid, the slide rail moves to enable the waste liquid receiving bottle to be positioned at the lower part of the liquid outlet of the purification column, when receiving useful liquid, the slide rail moves to enable the waste liquid receiving bottle to be positioned at the lower part of the liquid outlet of the purification column,
the receiving cup device consists of a receiving liquid bottle, a receiving waste liquid bottle and a slide rail.
Preferably, the purification column liquid level sensor adjusting device consists of a liquid level sensor and a moving device. The different used filler types of different experiments are different, and the quantity of filler is also different, causes the filler also to be different in the intraductal height of glass, consequently needs according to the filler height of difference in the glass pipe, adjusts level sensor's position.
Preferably, the purification column in-place detection device is used for proving that the purification column is not installed at the position when the purification column in-place detection device cannot detect the purification column, and the position does not need to be filled with the solvent.
The use method of the integrated solid phase extraction instrument comprises the following steps:
after the instrument is started, a solvent barrel lowest liquid level detection system detects whether a solvent barrel is in place and the amount of a solvent, a purification column in-place detection device detects whether a purification column is in place, a purification column liquid level sensor adjusting device is manually adjusted to enable a liquid level sensor to be in the proper position of the purification column, a solvent A to be filled is selected, a pipeline is filled with the solvent A through a metering pump and a multi-channel switching valve, and redundant liquid is discharged into a liquid adding waste liquid bottle; the tetrafluoro cock of the No. 1 purifying column is opened by the rotating manipulator of the purifying column; the liquid feeding transmission device moves a solvent filling port to the position above the No. 1 purifying column, after a fixed amount of solvent is filled, a purifying column liquid level sensor is opened, a receiving waste liquid bottle in the receiving cup device is positioned at the lower part of a purifying column liquid outlet, and the purifying column liquid level sensor closes a tetrafluoro piston of the purifying column when the purifying column liquid level sensor detects that the liquid level is changed from existence to nonexistence; filling 2/3/4/5/6 purification columns in sequence; after the solvent A is filled, the solvent B is sequentially filled, when the liquid level sensor of the purification column detects that the liquid level is changed from the liquid level to the non-liquid level, the tetrafluoro cock of the purification column is closed, and a receiving liquid bottle in the receiving device is positioned at the lower part of a liquid outlet of the purification column. And the sound and light alarm prompts a worker to manually fill the sample, and the worker continues the experiment after the manual filling of the sample is finished and presses the corresponding start key. And finally, sequentially adding the solvent C, putting the extracted solution in a receiving liquid bottle, and finishing the experiment.
Compared with the prior art, the utility model has the beneficial effects that: the solid phase extraction apparatus and the use method;
1. the device improves the accuracy and the working efficiency of the experiment, reduces the labor intensity, integrates activation, balance, sample loading, cleaning, dehydration, drying and elution, can be widely applied to sample analysis and experiments of food, medicines, environmental samples and the like, and is particularly suitable for the purification process of detecting samples of semi-volatile organic compounds, petroleum hydrocarbons and the like;
2. the automation degree is high, the operation is convenient, the solvent filling is accurate, the commodity purifying column can be replaced by the self-filling purifying column, the unattended operation can be realized during the work, and the practicability of the device is improved;
3. compared with the composition of a disposable commercial purification column, the self-filling purification column (absorbent cotton, 2g of anhydrous sodium sulfate, 2g of florisil and 2g of anhydrous sodium sulfate from bottom to top) which can be repeatedly used can be universally applied to the detection of semi-volatile organic matters and petroleum hydrocarbon organic matters.
Drawings
FIG. 1 is a schematic front view of the present invention;
FIG. 2 is a schematic diagram of a front view of the cup receiving device of the present invention;
FIG. 3 is a schematic cross-sectional view of a solvent barrel according to the present invention;
FIG. 4 is a schematic front view of the glass tube of the present invention;
FIG. 5 is a schematic front view of the spin chuck of the present invention;
FIG. 6 is a schematic view of the front view of the waste liquid receiving bottle of the present invention;
fig. 7 is a front view of the exercise device of the present invention.
In the figure: 1. a solvent barrel fixing shell; 2. a solvent barrel; 3. a solvent barrel level sensor; 4. a solvent barrel lowest liquid level detection system; 5. a housing; 6. purifying the column; 7. a rotating manipulator of the purifying column; 8. a tetrafluoro plug of the purification column; 9. a purifying column fixing clip; 10. a receiving cup device; 11. a metering pump; 12. a multi-channel switching valve; 13. adding a liquid waste liquid bottle; 14. a liquid feeding transmission device; 15. a display control device; 16. a purifying column on-site detection device; 17. a purification column liquid level sensor adjusting device; 18. a polytetrafluoroethylene pipeline; 19. a solvent filling port; 20. a glass tube; 21. a filler; 22. medical absorbent cotton; 23. a step-by-step reduction motor; 24. a plug chuck; 25. receiving the liquid bottle; 26. receiving a waste liquid bottle; 27. a slide rail; 28. a purification column liquid level sensor; 29. and (4) a movement device.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Referring to fig. 1-7, the present invention provides a technical solution: the utility model provides a solid phase extraction appearance, includes that host computer, solvent bucket minimum liquid level detecting system 4, host computer include casing 5 and be located 5 inside a plurality of extraction units of casing and public liquid feeding unit, and the structure of every extraction unit is the same, and every extraction unit is from supreme being in proper order down: the purification column 6, the purification column rotary manipulator 7 and a tetrafluoro cock 8 of the purification column are clamped together, and meanwhile, a purification column fixing clamp 9 fixes a glass tube and a receiving cup device 10 is placed at the lower part of a liquid outlet of the purification column; the common charging unit comprises: a metering pump 11, a multi-channel switching valve 12, a liquid feeding waste liquid bottle 13 and a liquid feeding transmission device 14.
Solvent bucket minimum liquid level detecting system 4, solvent bucket minimum liquid level detecting system 4 include solvent bucket 2, solvent bucket level sensor 3, solvent bucket set casing 1 and solvent bucket minimum liquid level detecting system 4.
A display control device 15 is arranged on one side of the outer surface of the shell 5, and the display control device 15 is electrically connected with the purification column rotary manipulator 7, the metering pump 11, the multi-channel switching valve 12, the liquid feeding transmission device 14, the solvent barrel liquid level sensor 3, the purification column on-site detection device 16, the purification column liquid level sensor adjusting device 17 and the like.
The public liquid adding unit comprises a polytetrafluoroethylene pipeline 18, a metering pump 11, a multi-channel switching valve 12, a liquid adding waste liquid bottle 13 and a liquid adding transmission device 14;
the material of the flow path of the multi-channel switching valve 12 and the flow path of the metering pump 11 is polytetrafluoroethylene material, and the material of the pipeline is polytetrafluoroethylene material, so that the liquid is prevented from being polluted; when a solvent barrel liquid level sensor 3 in a solvent barrel lowest liquid level detection system 4 detects that the liquid level of a solvent barrel 2 reaches the lowest liquid level, an alarm is sent to prompt a worker to add liquid in time; the metering pump 11 provides guarantee for accurate liquid filling; the multi-channel switching valve 12 provides guarantee for selecting which liquid to fill; when the liquid adding waste liquid bottle 13 instrument initially works, the waste liquid generated by emptying the pipeline and the waste liquid generated by switching to inject different liquids are all discharged into the liquid adding waste liquid bottle 13; the priming actuator 14 ensures that the solvent fill port 19 moves above the column 6 to be filled.
The purifying column 6 consists of a glass tube 20 (with an effective volume of 50ml) with a tetrafluoro cock of the purifying column, a filler 21 (absorbent cotton, 2g of sodium sulfate, 2g of Flori silica and 2g of sodium sulfate are respectively filled from bottom to top) and medical absorbent cotton 22;
the rotary manipulator 7 for the purifying column is composed of a stepping speed-reducing motor 23 and a cock chuck 24. The tetrafluoro cock 8 of the purification column can be rotated at the precision of 0.1 degree/step, the purification column 6 is switched on and off, and the purification column rotating manipulator 7 is composed of a stepping speed reducing motor 23 and a cock chuck 24.
The cup receiving device 10 is composed of a receiving liquid bottle 25, a receiving waste liquid bottle 26 and a slide rail 27, when receiving waste liquid, the slide rail 27 moves to enable the receiving waste liquid bottle 26 to be positioned at the lower part of the liquid outlet of the purification column, when receiving useful liquid, the slide rail 27 moves to enable the receiving liquid bottle 25 to be positioned at the lower part of the liquid outlet of the purification column, and the cup receiving device 10 is composed of the receiving liquid bottle 25, the receiving waste liquid bottle 26 and the slide rail 27.
The purifying column liquid level sensor adjusting device 17 is composed of a liquid level sensor 28 and a moving device 29. The type of the filler 21 used for different experiments is different, and the amount of the filler 21 is also different, so that the position of the liquid level sensor 28 needs to be adjusted according to the height of the filler 21 in the glass tube 20.
And the purifying column liquid level sensor adjusting device 17 is composed of a liquid level sensor 28 and a moving device 29.
The purification column in-place detection device 16 is provided with a purification column in-place detection device 16 for each purification column, and when the purification column in-place detection device 16 can not detect the purification column 6, the position does not need to be filled with liquid.
A use method of a solid phase extractor comprises the following steps:
if the solvent barrel lowest liquid level detection system 4, the purification column 6, the KD concentration bottle and the like are prepared, selecting a solvent A to be filled, filling the pipeline with the solvent A through a metering pump 11 and a multi-channel switching valve 12, and discharging redundant liquid into a liquid adding waste liquid bottle 13; the tetrafluoro cock 8 of the purification column at the No. 1 position is opened by the purification column rotary manipulator 7; the liquid feeding transmission device 14 moves the solvent filling port 19 to the upper part of the No. 1 purification column, and fills a certain amount of solvent, and at the moment, the receiving waste liquid bottle 26 in the receiving cup device 10 is positioned at the lower part of the liquid outlet of the purification column. Then opening the purification column liquid level sensor 28, detecting that the liquid level is lower than the purification column liquid level sensor 28, and closing the tetrafluoro cock 8 of the purification column to sequentially fill 2/3/4/5/6 purification columns. After the solvent A is filled, the solvent B is sequentially filled, when the liquid level of the solvent B in the purification column is lower than the purification column liquid level sensor 28, the tetrafluoro cock 8 of the purification column is closed, and the receiving liquid bottle 25 in the receiving cup device 10 is positioned at the lower part of the liquid outlet of the purification column. And the sound and light alarm prompts a worker to manually fill the sample, and the worker presses the corresponding start button to continue the experiment. And finally, sequentially adding the solvent C, putting the extracted solution in a liquid receiving bottle 25, and finishing the experiment.
Those not described in detail in this specification are within the skill of the art.
Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the utility model, the scope of which is defined in the appended claims and their equivalents.
Claims (9)
1. The utility model provides a solid phase extraction appearance, its characterized in that, solid phase extraction appearance include host computer, solvent bucket minimum liquid level detecting system (4), the host computer includes casing (5) and is located inside a plurality of extraction units and public liquid feeding unit of casing (5), the structure of every extraction unit is the same, every extraction unit is from bottom to top in proper order: the purification column (6), the purification column rotary manipulator (7) and the tetrafluoro cock (8) of the purification column are clamped together, and simultaneously, the purification column fixing clamp (9) fixes the glass tube and the receiving cup device (10) is placed at the lower part of the liquid outlet of the purification column; the common charging unit comprises: a metering pump (11), a multi-channel switching valve (12), a liquid feeding waste liquid bottle (13) and a liquid feeding transmission device (14).
2. The solid phase extractor of claim 1, wherein: the solvent bucket minimum liquid level detection system (4) comprises a solvent bucket (2), a solvent bucket liquid level sensor (3), a solvent bucket fixing shell (1) and a solvent bucket minimum liquid level detection system (4).
3. The solid phase extractor of claim 1, wherein: and a display control device (15) is arranged on one side of the outer surface of the shell (5), and the display control device (15) is electrically connected with a purification column rotating manipulator (7), a metering pump (11), a multi-channel switching valve (12), a liquid feeding transmission device (14), a solvent barrel liquid level sensor (3), a purification column on-site detection device (16), a purification column liquid level sensor adjusting device (17) and the like.
4. The solid phase extractor of claim 1, wherein: the public liquid adding unit comprises a polytetrafluoroethylene pipeline (18), a metering pump (11), a multi-channel switching valve (12), a liquid adding waste liquid bottle (13) and a liquid adding transmission device (14).
5. The solid phase extractor of claim 1, wherein: the purifying column (6) consists of a glass tube (20) with a tetrafluoro cock (8) of the purifying column, a filler (21) and medical absorbent cotton (22).
6. The solid phase extractor of claim 1, wherein: the rotary manipulator (7) of the purifying column consists of a stepping speed reducing motor (23) and a cock chuck (24).
7. The solid phase extractor of claim 1, wherein: the cup receiving device (10) consists of a liquid receiving bottle (25), a waste liquid receiving bottle (26) and a sliding rail (27).
8. A solid phase extractor according to claim 3 wherein: the purification column liquid level sensor adjusting device (17) consists of a liquid level sensor (28) and a moving device (29).
9. A solid phase extractor according to claim 3 wherein: the purification columns are provided with purification column in-place detection devices (16), and each purification column is provided with a purification column in-place detection device (16).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202122303333.XU CN216484800U (en) | 2021-09-23 | 2021-09-23 | Solid phase extraction instrument |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202122303333.XU CN216484800U (en) | 2021-09-23 | 2021-09-23 | Solid phase extraction instrument |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN216484800U true CN216484800U (en) | 2022-05-10 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202122303333.XU Active CN216484800U (en) | 2021-09-23 | 2021-09-23 | Solid phase extraction instrument |
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| CN (1) | CN216484800U (en) |
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2021
- 2021-09-23 CN CN202122303333.XU patent/CN216484800U/en active Active
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