CN215004429U - Device for sampling liquid with equal volume - Google Patents

Device for sampling liquid with equal volume Download PDF

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Publication number
CN215004429U
CN215004429U CN202120845641.2U CN202120845641U CN215004429U CN 215004429 U CN215004429 U CN 215004429U CN 202120845641 U CN202120845641 U CN 202120845641U CN 215004429 U CN215004429 U CN 215004429U
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CN
China
Prior art keywords
liquid
cavity
sample
piston
sampling
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Expired - Fee Related
Application number
CN202120845641.2U
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Chinese (zh)
Inventor
吴丽
唐曲
丛辉
秦玉岭
胡文琪
陈欢欢
毛天智
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Nantong University
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Nantong University
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Priority to CN202120845641.2U priority Critical patent/CN215004429U/en
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Publication of CN215004429U publication Critical patent/CN215004429U/en
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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Abstract

The utility model discloses a device for sampling liquid with equivalent volume, which comprises a liquid unit array, a two-dimensional moving platform and a liquid receiving bottle; the liquid unit array is a matrix structure formed by a plurality of sample tubes to be tested and is arranged on a two-dimensional moving platform; a liquid storage cavity with an opening at the upper part is arranged in the sample tube to be tested, an isolation cavity is formed in the bottom of the liquid storage cavity, an outflow cavity is arranged below the isolation cavity, a sample injection piston is arranged in the liquid storage cavity, and a sample outlet piston is arranged in the outflow cavity; the sample injection piston and the sample outlet piston are coaxially connected through a linkage rod, and one end of the linkage rod, which is close to the sample injection piston, extends to the outer side of the liquid storage cavity; the end part of the linkage rod extending to the outer side of the liquid storage cavity is connected with a controller; the liquid receiving bottle is arranged right below the sample tube outflow cavity to be tested. Compared with the prior art, the device has low operation cost, can sample quickly and can greatly improve the analysis efficiency.

Description

Device for sampling liquid with equal volume
Technical Field
The utility model belongs to the medical analysis field, concretely relates to a device for equivalent volume liquid sample.
Background
The sample application system of a commercial biochemical analyzer is a key device for applying a predetermined amount of liquid sample and detection reagent to a predetermined reaction container to perform a reaction, and includes a quantitative pipette, a sample application needle, and the like. Before the device operates, a sample to be detected (such as blood) needs to be dispensed into different reagent tubes in advance and fixed. The sample sucker is connected with a sample adding needle, and a certain amount of sample is taken out from the reagent tube and is injected into the reaction container under the control of the system. The system thoroughly cleans the sample suction device and the sample adding needle, thereby ensuring that cross contamination can not occur in the repeated sampling process. The system is complex, requires pre-cleaning for each sampling, and is time consuming and costly. The sample injection needle is expensive, and once damaged, the replacement cost is high. Therefore, designing a device with similar low operating cost and fast sampling can greatly improve the analysis efficiency.
SUMMERY OF THE UTILITY MODEL
To the above problem, the utility model relates to a device for equivalent volume liquid sample.
A device for automatically measuring and taking liquid with equal volume comprises a liquid unit array, a two-dimensional moving platform and a liquid receiving bottle, wherein the liquid unit array is a matrix structure formed by a plurality of sample tubes to be tested and is arranged on the two-dimensional moving platform; a liquid storage cavity with an opening at the upper part is arranged in the sample tube to be tested, an isolation cavity is formed in the bottom of the liquid storage cavity, an outflow cavity is arranged below the isolation cavity, a sample injection piston is arranged in the liquid storage cavity, and a sample outlet piston is arranged in the outflow cavity; the sample injection piston and the sample outlet piston are coaxially connected through a linkage rod, and one end of the linkage rod, which is close to the sample injection piston, extends to the outer side of the liquid storage cavity; the end part of the linkage rod extending to the outer side of the liquid storage cavity is connected with a controller;
the liquid receiving bottle is arranged right below the sample tube outflow cavity to be tested.
Further, the inner diameter of the isolation cavity is smaller than the inner diameters of the liquid storage cavity and the outflow cavity.
Furthermore, the diameter of the sample injection piston is larger than the inner diameter of the isolation cavity and smaller than the inner diameter of the liquid storage cavity; the diameter of the sample outlet piston is larger than the inner diameter of the isolation cavity and smaller than the inner diameter of the outflow cavity.
Further, the distance between the sample injection piston and the sample outlet piston is larger than the height of the isolation cavity.
Furthermore, the bottom of the outflow cavity is provided with a through hole.
Furthermore, the inner surface of the sample tube to be tested, the sample injection piston, the sample outlet piston and the surface of the linkage rod are made of super-hydrophobic materials.
Furthermore, the controller is connected with the linkage rod through a bayonet.
Advantageous effects
Compared with the prior art, the device has low running cost, can sample quickly, can greatly improve the analysis efficiency, and solves the problems of high cost and long sampling time of the sampling system of the biochemical analyzer on the market at present. The sampling of a single sample is independent operation, and a cleaning process of an injection needle is not needed, so that the sampling time is greatly shortened, and the cross contamination among samples can not occur.
Drawings
Fig. 1 is a schematic view of the device of the present invention.
FIG. 2 is a perspective view (left) and a sectional view (right) of a sample tube to be tested.
Fig. 3 is a schematic cross-sectional view of the sampling operation principle of the sample tube to be tested.
Wherein, 1-linkage rod, 2-controller, 3-liquid receiving bottle, 4-liquid storage cavity, 5-sample injection piston, 6-isolation cavity, 7-sample outlet piston and 8-outlet cavity.
Detailed Description
The present invention will be further described with reference to the accompanying drawings.
A device for automatically measuring and taking liquid with equal volume comprises a liquid unit array, a two-dimensional moving platform and a liquid receiving bottle 3, wherein the liquid unit array is a matrix structure formed by a plurality of sample tubes to be tested and is arranged on the two-dimensional moving platform; the size of the liquid cell array depends on the test throughput and site limitations, and the analysis throughput can be increased by increasing the number of device cells. This intraductal stock solution chamber 4 that is equipped with upper portion open-ended of sample that awaits measuring, the isolation chamber 6 has been seted up to stock solution chamber bottom, and 6 below in isolation chamber are equipped with outflow chamber 8, there is the through-hole outflow chamber 8 bottom. The inner diameter of the isolation cavity 6 is smaller than the inner diameters of the liquid storage cavity 4 and the outflow cavity 8.
A sample injection piston 5 is arranged in the liquid storage cavity 4, and a sample outlet piston 7 is arranged in the outflow cavity 8; the sample injection piston 5 and the sample outlet piston 7 are coaxially connected through a linkage rod 1, and one end of the linkage rod 1, which is close to the sample injection piston 5, extends to the outer side of the liquid storage cavity 4; the end part of the linkage rod 1 extending to the outer side of the liquid storage cavity 4 is connected with a controller 2, and the linkage rod 1 is driven by the controller 2 to move up and down; the controller 2 is connected with the linkage rod 2 through a bayonet. The diameter of the sample injection piston 5 is larger than the inner diameter of the isolation cavity 6 and smaller than the inner diameter of the liquid storage cavity 4; the diameter of the sample outlet piston 7 is larger than the inner diameter of the isolation cavity 6 and smaller than the inner diameter of the outflow cavity 8. The distance between the sample injection piston 5 and the sample outlet piston 7 is larger than the height of the isolation cavity 6. The inner surface of the sample tube to be tested, the sample feeding piston 5, the sample discharging piston 7 and the surface of the linkage rod 1 are made of super-hydrophobic materials, so that the difference between parallel samples caused by surface adhesion is prevented. The liquid receiving bottle 3 is arranged right below the sample tube outflow cavity 8 to be tested.
The working principle is as follows: when the device is used, a sample tube to be tested is mounted and placed on a two-dimensional moving platform, the platform returns to an initial position, the sample tube to be tested is moved to a sampling position through the two-dimensional moving platform for sampling, after the sample tube to be tested is moved to the sampling position, the controller 2 grabs the upper end of the linkage rod 1 to drive the linkage rod 1 to move upwards, the sample injection piston 5 is opened along the wall of the bottle, and liquid in the bottle flows into the isolation cavity 6 under the action of gravity; then the controller 2 grabs the linkage rod 1 to move downwards, the sample injection piston 5 is tightly attached to the bottle wall, the sample outlet piston 7 is opened along with the bottle wall, the liquid in the isolation cavity 6 flows into the flow outlet cavity 8, and flows into the liquid receiving bottle 3 through a through hole below the flow outlet cavity 8, and sampling of one unit is completed. Then, the next sample tube to be tested is moved to the upper part of the liquid receiving bottle 3, and the sampling operation is repeated until the sampling is finished.
The above description is only a preferred embodiment of the present invention, and it should be noted that: for those skilled in the art, without departing from the principle of the present invention, several improvements and modifications can be made, and these improvements and modifications should also be considered as the protection scope of the present invention.

Claims (7)

1. A device for sampling liquid with equal volume comprises a liquid unit array, a two-dimensional moving platform and a liquid receiving bottle (3),
the liquid unit array is a matrix structure formed by a plurality of sample tubes to be tested and is arranged on a two-dimensional moving platform; a liquid storage cavity (4) with an opening at the upper part is arranged in the sample tube to be tested, an isolation cavity (6) is arranged at the bottom of the liquid storage cavity, an outflow cavity (8) is arranged below the isolation cavity (6), a sample injection piston (5) is arranged in the liquid storage cavity (4), and a sample outlet piston (7) is arranged in the outflow cavity (8); the sample injection piston (5) and the sample outlet piston (7) are coaxially connected through a linkage rod (1), and one end, close to the sample injection piston (5), of the linkage rod (1) extends to the outer side of the liquid storage cavity (4); the end part of the linkage rod (1) extending to the outer side of the liquid storage cavity (4) is connected with a controller (2);
the liquid receiving bottle (3) is arranged right below the sample tube outflow cavity (8) to be tested.
2. Device for equivalent volumetric liquid sampling according to claim 1, characterized in that the internal diameter of the separation chamber (6) is smaller than the internal diameters of the reservoir chamber (4) and the outflow chamber (8).
3. The device for sampling an equivalent volume of liquid according to claim 1, wherein the diameter of the sampling piston (5) is larger than the inner diameter of the isolation chamber (6) and smaller than the inner diameter of the liquid storage chamber (4); the diameter of the sample outlet piston (7) is larger than the inner diameter of the isolation cavity (6) and smaller than the inner diameter of the flow outlet cavity (8).
4. Device for equivalent volume liquid sampling according to claim 1, characterized in that the distance between the sampling piston (5) and the sampling piston (7) is greater than the height of the separation chamber (6).
5. Device for the equivalent volumetric liquid sampling according to claim 1, characterized in that the outflow chamber (8) has a through hole at its bottom.
6. The device for sampling the liquid with the same volume as the liquid with the same volume as the liquid with the same volume as the liquid with the same volume as the liquid with the same volume as the liquid with the same volume as the liquid with the same volume as the liquid with the same volume as the liquid with the same volume as the liquid with the liquid.
7. A device for equivalent volume liquid sampling according to claim 1, wherein the controller (2) and the lever (1) are connected together by a bayonet connection.
CN202120845641.2U 2021-04-23 2021-04-23 Device for sampling liquid with equal volume Expired - Fee Related CN215004429U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202120845641.2U CN215004429U (en) 2021-04-23 2021-04-23 Device for sampling liquid with equal volume

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202120845641.2U CN215004429U (en) 2021-04-23 2021-04-23 Device for sampling liquid with equal volume

Publications (1)

Publication Number Publication Date
CN215004429U true CN215004429U (en) 2021-12-03

Family

ID=79095324

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202120845641.2U Expired - Fee Related CN215004429U (en) 2021-04-23 2021-04-23 Device for sampling liquid with equal volume

Country Status (1)

Country Link
CN (1) CN215004429U (en)

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CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20211203

CF01 Termination of patent right due to non-payment of annual fee