CN213285361U - Coil array for improving focusing of transcranial magnetic stimulation and magnetic stimulation device - Google Patents
Coil array for improving focusing of transcranial magnetic stimulation and magnetic stimulation device Download PDFInfo
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- CN213285361U CN213285361U CN202021123684.1U CN202021123684U CN213285361U CN 213285361 U CN213285361 U CN 213285361U CN 202021123684 U CN202021123684 U CN 202021123684U CN 213285361 U CN213285361 U CN 213285361U
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- 238000011491 transcranial magnetic stimulation Methods 0.000 title claims abstract description 20
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Abstract
The utility model provides a coil array and magnetic stimulation device for improving the focusing of transcranial magnetic stimulation. The coil array comprises a plurality of non-intersecting polygonal coils which are positioned in the same plane or the same curved surface, and at least one side of each polygonal coil is adjacent to and parallel to the sides of other polygonal coils. When the directions of the current of the two adjacent sides of the two polygonal coils are opposite, a magnetic stimulation focus point is formed below the two adjacent sides, and the focus point is slender, so that the focus point is matched with the appearance of nerve cells, the stimulation of a non-target area of the head is reduced, and the effectiveness and the accuracy of the stimulation on nerve tissues are enhanced; by supplying power to the polygonal coils with different numbers, single-point stimulation or multi-point stimulation area selection can be realized, and multiple areas with different diseases can be stimulated; the structure of the coil array enables the current flow directions in all the electrified coils to be the same (such as all the electrified coils are anticlockwise or all the electrified coils are clockwise), and the magnetic stimulation circuit module structure is beneficial to reducing the complexity of the magnetic stimulation circuit module structure and reducing the cost.
Description
Technical Field
The utility model relates to a through cranium magnetic stimulation technical field, concretely relates to improve coil array and magnetic stimulation device of through cranium magnetic stimulation focusing nature.
Background
Transcranial Magnetic Stimulation (TMS) is a noninvasive, painless and contactless biostimulation technology and is mainly used in the treatment fields of depression, migraine, nervous tinnitus and the like. The transcranial magnetic stimulation device mainly comprises a magnetic stimulation coil and a magnetic stimulation circuit, time-varying current generated by the magnetic stimulation circuit is used for increasing excitation of the coil, the time-varying current passes through the coil to excite a time-varying magnetic field in the air, the magnetic field penetrates through the scalp, the skull and the like to stimulate cerebral neurons, an induction electric field is generated in the body, and when the strength reaches a cell Movement Threshold (MT), the change of the nerve cell membrane potential can be caused to generate hyperpolarization or depolarization. The induction electric field with small focusing area and large stimulation intensity generated in a specific area is an important index for stimulation evaluation of TMS performance.
In recent years, researchers have conducted a great deal of research to improve the stimulus focality and depth of stimulation of TMS. The stimulating coil is an important component for generating an electromagnetic field, and the material, the structure, the excitation form and the like of the stimulating coil directly influence the electromagnetic field distribution. Bark et al originally designed round stimulation coils for use with TMS instruments that had a simple structure and had limited brain stimulation. Two circular coil structures with a distance of 2cm are firstly proposed by Ueno to realize the magnetic stimulation of local cerebral cortex. Later many studied multi-coil structures, such as circular deformation coils, Slink and its improved coils, multi-combination structures and the addition of window shields, achieved better stimulation to some extent. However, this technique is large in stimulation area, and the multi-stimulation area is not good in co-stimulation effect.
SUMMERY OF THE UTILITY MODEL
In order to overcome the defects in the prior art, the present invention provides a coil array and a magnetic stimulation device for improving the focusing of transcranial magnetic stimulation.
In order to achieve the above objects of the present invention, according to the first aspect of the present invention, the present invention provides a coil array for improving focusing of transcranial magnetic stimulation, comprising a plurality of non-intersecting polygonal coils located on the same plane or the same curved surface, wherein each polygonal coil has at least one side adjacent to and parallel to the sides of other polygonal coils.
The beneficial effects of the above technical scheme are: when the directions of the current of the two adjacent sides of the two polygonal coils are opposite, a magnetic stimulation focus point is formed below the two adjacent sides, and the focus point is slender, so that the focus point is matched with the appearance of nerve cells, the stimulation of a non-target area of the head is reduced, and the effectiveness and the accuracy of the stimulation on nerve tissues are enhanced; by supplying power to the polygonal coils with different numbers, single-point stimulation or multi-point stimulation area selection can be realized, multi-point stimulation is realized, multiple areas of different diseases can be stimulated, and application to multiple treatment areas is achieved; the structure of the coil array enables the current flow directions in all the electrified coils to be the same (such as all the electrified coils are anticlockwise or all the electrified coils are clockwise), so that the complexity of the structure of the magnetic stimulation circuit module for supplying power to the coil array is reduced, and the cost is reduced. In a preferred embodiment of the present invention, the polygonal coil is a regular polygonal coil or an isosceles trapezoid coil, and the polygonal coil is periodically arranged to form a coil array.
The beneficial effects of the above technical scheme are: the focusing performance of coils in the array is improved, the focusing performance of magnetic stimulation focusing points is improved, and multi-point stimulation in a small area is realized conveniently.
In a preferred embodiment of the present invention, the polygonal coils are annularly distributed around the same point for at least one week or less.
The beneficial effects of the above technical scheme are: the shape of the brain can be matched; at least two sides of most polygonal coils are respectively adjacent to adjacent polygonal coils to form a magnetic stimulation focusing point, so that the utilization rate is improved, and the aggregation of stimulation points is improved.
In a preferred embodiment of the present invention, the polygonal coil is a multi-turn coil distributed in a planar or three-dimensional manner.
The beneficial effects of the above technical scheme are: the multi-turn coil is beneficial to increasing the strength and the stimulation depth of the stimulation area, and the effective stimulation to the nerve tissue is realized.
In a preferred embodiment of the present invention, all the polygonal coils have the same shape and size.
The beneficial effects of the above technical scheme are: convenient production and low cost.
In a preferred embodiment of the present invention, the coil array includes six polygonal coils, the polygonal coils are equilateral triangles, one vertex of each of the six polygonal coils faces the same point, and the six polygonal coils surround the same point for a circle.
The beneficial effects of the above technical scheme are: the equilateral triangle is convenient for winding and obtaining, and the annular triangular coil array enables any coil to have two sides which are respectively adjacent to the adjacent polygonal coils to form a magnetic stimulation focus point, so that the utilization rate is improved, and the aggregation of the stimulation points is improved.
In a preferred embodiment of the present invention, two equilateral triangle coils are adjacent and parallel, and the distance between the two sides is 3 mm; and/or the equilateral triangle coil is a multi-turn coil distributed on a plane, and the side length of the innermost turn coil of the equilateral triangle coil is 30 cm.
The beneficial effects of the above technical scheme are: the 3mm distance can avoid the interference between the coils and improve the reliability while ensuring the strength and the depth of the magnetic stimulation. The structure of equilateral triangle coil is convenient for the laminating and is fixed in the brain, matches with the brain appearance size.
In order to achieve the above object of the present invention, according to a second aspect of the present invention, the present invention provides a magnetic stimulation device, including the coil array and the magnetic stimulation circuit module of the present invention; the magnetic stimulation circuit module supplies power to the polygonal coils of the coil array, and the current flowing directions of two adjacent and parallel sides of the two polygonal coils are opposite.
The beneficial effects of the above technical scheme are: the magnetic stimulation circuit module supplies power to the single or different combined polygonal coils, so that single-point stimulation or multi-point stimulation and stimulation area selection can be realized, multiple areas with different diseases can be stimulated, and multiple treatment areas can be applied; the magnetic stimulation circuit module provides currents in the same direction (such as all counterclockwise or all clockwise) for the polygonal coils needing power supply, so that the complexity and the cost of the structure of the magnetic stimulation circuit module are reduced; when the adjacent two sides of the two polygonal coils are opposite in electrified current direction, a magnetic stimulation focus point is formed below the adjacent two sides, and the focus point is slender, so that the focus point is favorably matched with the appearance of nerve cells, the stimulation of a non-target area of the head is reduced, and the effectiveness and the accuracy of the stimulation of nerve tissues are enhanced.
Additional aspects and advantages of the invention will be set forth in part in the description which follows and, in part, will be obvious from the description, or may be learned by practice of the invention.
Drawings
The above and/or additional aspects and advantages of the present invention will become apparent and readily appreciated from the following description of the embodiments, taken in conjunction with the accompanying drawings of which:
FIG. 1 is a schematic diagram of a coil array in a preferred embodiment of the present invention;
FIG. 2 is a schematic view of a coil array in another preferred embodiment of the present invention;
FIG. 3 is a schematic view of a coil array in accordance with still another preferred embodiment of the present invention;
FIG. 4 is a schematic view of a coil array in accordance with still another preferred embodiment of the present invention;
FIG. 5 is a schematic view of a coil array in accordance with yet another preferred embodiment of the present invention;
fig. 6 is a schematic structural view of a polygonal coil according to a preferred embodiment of the present invention;
fig. 7 is a partial system block diagram of a magnetic stimulation device according to a preferred embodiment of the present invention.
Detailed Description
Reference will now be made in detail to embodiments of the present invention, examples of which are illustrated in the accompanying drawings, wherein like reference numerals refer to the same or similar elements or elements having the same or similar function throughout. The embodiments described below with reference to the drawings are exemplary only for the purpose of explaining the present invention, and should not be construed as limiting the present invention.
In the description of the present invention, unless otherwise specified and limited, it is to be noted that the terms "mounted," "connected," and "connected" are to be construed broadly, and may be, for example, mechanically or electrically connected, or may be connected between two elements through an intermediate medium, or may be directly connected or indirectly connected, and specific meanings of the terms may be understood by those skilled in the art according to specific situations.
The utility model discloses a coil array for improving focusing of transcranial magnetic stimulation, as shown in figures 1-5, in a preferred embodiment, the coil array comprises a plurality of non-intersecting polygonal coils which are positioned on the same plane or the same curved surface, and each polygonal coil has at least one side which is adjacent and parallel to the sides of other polygonal coils.
In the present embodiment, the curved surface is preferably, but not limited to, a hemispherical surface, a cambered surface, or a curved surface matching with the external dimension of the human head.
In the present embodiment, each polygon coil in the coil array is adjacent to at least one other polygon coil and has two adjacent parallel sides, as shown in fig. 4, the distance between the two adjacent parallel sides is L, and L ranges from 0 to 5mm, preferably, L is 3 mm. When the device is powered on, a roughly annular field distribution can be formed on a short-distance plane of the powered polygonal coil, when the directions of the powered currents on two adjacent parallel sides are opposite, the magnetic fields in the middle area of the two sides can be superposed, and when the currents are time-varying currents, magnetic stimulation focusing points can be formed under the two sides in an induction mode.
In the present embodiment, the magnetic field distribution formed in the polygonal coil in a certain distance and plane has a multiple relation with the number of turns of the coil, and preferably, the polygonal coil is a multi-turn coil.
In the present embodiment, the polygonal coil is preferably, but not limited to, a triangle (as shown in fig. 1), a parallelogram, a square (as shown in fig. 4), an isosceles trapezoid (as shown in fig. 2 and 5), a rectangle, and a regular hexagon (as shown in fig. 3). The polygonal coil can be a single-turn or multi-turn coil, and in the case of the multi-turn coil, the polygonal coil can be a planar distribution (as shown in fig. 6) or a three-dimensional distribution (as the coils are wound in a superposition manner from the height direction). The polygonal coil is preferably, but not limited to, tightly wound with an enameled wire, such as an enameled wire with a diameter of preferably, but not limited to, 2 mm. In the implementation, the side length and the number of turns of the coil can be adjusted according to the stimulation requirement.
In this embodiment, the polygonal coils may have the same shape and size, different shapes, and different sizes, for example, one column in the array is a square, and the other column is a triangle.
In a preferred embodiment, the polygonal coils are regular polygonal coils or isosceles trapezoid coils, and the polygonal coils are arranged in a period to form a coil array. As shown in fig. 1-5, the array format is preferably, but not limited to, circular, rectangular. Preferably, the polygonal coils are annularly distributed around the same point for at least one circle or less, such as one circle as shown in fig. 1 and 2, the coil array form can be concentric rings when the annular distribution is more than one circle, and the array form can be arc-shaped when the annular distribution is less than one circle, such as a half ring, a quarter ring, and the like.
In a preferred embodiment, as shown in fig. 1, the coil array comprises six polygonal coils, the polygonal coils are equilateral triangles, one vertex of each of the six polygonal coils faces a same point, and the six polygonal coils are annularly distributed around the same point for one circle. Preferably, two equilateral triangular coils are spaced 3mm apart from each other on adjacent and parallel sides. Preferably, as shown in fig. 6, the equilateral triangle coil is a planar multi-turn coil, the number of turns is preferably, but not limited to, 10 turns, and the side length X of the innermost turn coil of the equilateral triangle coil is 30 cm.
In this embodiment, the multi-turn coil includes a first, a second, a third, a fourth, a fifth and a sixth equilateral triangle multi-turn coils, all the coils are on the same plane, the side length and the number of turns of the inner triangle of each coil are equal, and the enameled wires of the same specification are used, every two adjacent sides are placed in parallel, one vertex angle of each coil points to a central point to form an annular coil array, the directions of the energizing currents of the two adjacent sides are opposite, the coil array forms six groups of adjacent sides which respectively correspond to six groups of stimulation areas under the coils, and by adjusting the on-off of each energizing coil, the selection of a single-point stimulation area and a multi-point stimulation area can be realized while the stimulation focusing performance of the coils is improved, and when the coils 1 and 2 are energized, stimulation points are formed between the two adjacent parallel sides of the coils 1 and 2. In the present embodiment, as shown in fig. 1, i is an energization current in a coil, an arrow in each coil is a direction of the energization current, and directions of currents in adjacent two sides are opposite. The stimulation of single target point or multiple target points is realized by controlling the on-off of multiple groups of coils. The stimulation intensity and the stimulation area can adjust the side length, the turn number and the structure of the coil unit according to the position and the number of the stimulation points.
In the embodiment, the coil array is designed, the triangular coil is used for improving the focusing property of a stimulation area and reducing the stimulation of a non-target area of the head; the strength and the stimulation depth of a stimulation area are increased through the multi-coil combined design, and effective stimulation on nerve tissues is realized; meanwhile, the multi-point stimulation is realized by configuring the current directions of different coils, and multi-areas of different diseases can be stimulated, so that the application of multiple treatment areas is achieved.
The utility model also discloses a magnetic stimulation device, in a preferred embodiment, as shown in fig. 7, comprising the coil array and the magnetic stimulation circuit module; the magnetic stimulation circuit module supplies power to the polygonal coils of the coil array, and the current flowing directions of two adjacent and parallel sides of the two polygonal coils are opposite.
In this embodiment, preferably, the magnetic stimulation circuit module includes a current source and a plurality of switches, the current source includes one or more current output channels, and is a time-varying current source, preferably but not limited to an existing square wave current source, a triangular wave current source, a sine wave current source, and the like; the polygonal coil has an A terminal and a B terminal. The switch may be a manual switch, preferably but not limited to an existing dip switch, push button switch, etc.
In this embodiment, when the current source includes one current output channel, the positive output terminals of the current output channels of the current source are connected to the a terminals of all the polygonal coils, respectively, the negative output terminals of the current output channels of the current source are connected to the B terminals of all the polygonal coils, respectively, and a switch is provided on the connection path of the positive output terminal of the current output channel to the a terminal of each polygonal coil or on the connection path of the negative output terminal of the current output channel to the B terminal of each polygonal coil.
In this embodiment, when the current source includes a plurality of current output channels, the current output channels correspond to the polygonal coils one to one, a positive output terminal and a negative output terminal of each current output channel are connected to the a terminal and the B terminal of the corresponding polygonal coil, respectively, and a switch is provided on a connection path of the positive output terminal of each current output channel to the a terminal of the corresponding polygonal coil or a connection path of the negative output terminal of each current output channel to the B terminal of the corresponding polygonal coil.
In the description herein, references to the description of the term "one embodiment," "some embodiments," "an example," "a specific example," or "some examples," etc., mean that a particular feature, structure, material, or characteristic described in connection with the embodiment or example is included in at least one embodiment or example of the invention. In this specification, the schematic representations of the terms used above do not necessarily refer to the same embodiment or example. Furthermore, the particular features, structures, materials, or characteristics described may be combined in any suitable manner in any one or more embodiments or examples.
While embodiments of the present invention have been shown and described, it will be understood by those of ordinary skill in the art that: various changes, modifications, substitutions and alterations can be made to the embodiments without departing from the principles and spirit of the invention, the scope of which is defined by the claims and their equivalents.
Claims (10)
1. A coil array for improving the focusing of transcranial magnetic stimulation is characterized by comprising a plurality of non-intersected polygonal coils which are located in the same plane or the same curved surface, each polygonal coil is adjacent to at least one polygonal coil in the coil array, and each polygonal coil has one side which is adjacent to and parallel to one side of the adjacent polygonal coil.
2. The coil array for improving focusing of transcranial magnetic stimulation according to claim 1, wherein the polygonal coils are regular polygonal coils or isosceles trapezoid coils, and the polygonal coils are arranged in a cycle to form the coil array.
3. The coil array for improving focusing of transcranial magnetic stimulation according to claim 1, wherein two adjacent and parallel sides of the two polygonal coils are spaced apart by a distance L, and the value of L ranges from 0 mm to 5 mm.
4. The coil array for improving focusing of transcranial magnetic stimulation according to claim 1, wherein the polygonal coils are annularly distributed around a same point for at least one circle or less.
5. The coil array for improving focusing of transcranial magnetic stimulation according to claim 1, wherein the polygonal coil is a planar or a stereoscopic multi-turn coil.
6. The coil array for improving focusing of transcranial magnetic stimulation according to any one of claims 1-5, wherein all of the polygonal coils are identical in shape and size.
7. The coil array for improving focusing of transcranial magnetic stimulation according to claim 6, wherein the coil array comprises six polygonal coils, the polygonal coils are equilateral triangles, one vertex of each of the six polygonal coils faces to a same point, and the six polygonal coils are annularly distributed around the same point for a circle.
8. The coil array for improving focusing of transcranial magnetic stimulation according to claim 7, wherein two adjacent and parallel sides of the equilateral triangular coils are 3mm apart;
and/or the equilateral triangle coil is a multi-turn coil distributed on a plane, and the side length of the innermost turn coil of the equilateral triangle coil is 30 cm.
9. A magnetic stimulation device comprising a coil array according to any one of claims 1 to 8, a magnetic stimulation circuit module;
the magnetic stimulation circuit module supplies power to the polygonal coils of the coil array, and the current flowing directions of two adjacent and parallel sides of the two polygonal coils are opposite.
10. The magnetic stimulation device of claim 9, wherein the magnetic stimulation circuit module comprises a current source and a plurality of switches, the current source comprising one or more current output channels; the polygonal coil has an A terminal and a B terminal;
when the current source comprises a current output channel, the positive output end of the current output channel of the current source is respectively connected with the A terminals of all the polygonal coils, the negative output end of the current output channel of the current source is respectively connected with the B terminals of all the polygonal coils, and a switch is arranged on the connection path of the positive output end of the current output channel and the A terminal of each polygonal coil or the connection path of the negative output end of the current output channel and the B terminal of each polygonal coil;
when the current source comprises a plurality of current output channels, the current output channels correspond to the polygonal coils one by one, the positive output end and the negative output end of each current output channel are respectively connected with the A terminal and the B terminal of the corresponding polygonal coil, and a switch is arranged on the connection path of the positive output end of each current output channel and the A terminal of the corresponding polygonal coil or the connection path of the negative output end of each current output channel and the B terminal of the corresponding polygonal coil.
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| US20220105341A1 (en) * | 2020-10-01 | 2022-04-07 | Minnesota Medical Physics Llc | Method and apparatus for cancer treatment |
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| US20220105341A1 (en) * | 2020-10-01 | 2022-04-07 | Minnesota Medical Physics Llc | Method and apparatus for cancer treatment |
| US11571560B2 (en) * | 2020-10-01 | 2023-02-07 | Minnesota Medical Physics Llc | Method and apparatus for cancer treatment |
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