CN213148740U

CN213148740U - Magnetic nanoparticle detection device convenient to detect

Info

Publication number: CN213148740U
Application number: CN202020828608.4U
Authority: CN
Inventors: 李超
Original assignee: Heze University
Current assignee: Heze University
Priority date: 2020-05-18
Filing date: 2020-05-18
Publication date: 2021-05-07
Anticipated expiration: 2030-05-18

Abstract

The utility model discloses a magnetism nanoparticle detection device convenient to detect relates to SERS detection area, comprising a base plate, the SERS substrate groove has been seted up to the top side of bottom plate, the magnet mounting groove has been seted up on the top side inner wall in SERS substrate groove. The utility model discloses it is rational in infrastructure, when the magnetism of magnet disappears or magnetism weakens, make the pin withdraw from the column casing through outwards pulling open the pin, rotatory pivot makes it rotate 90 degrees, the rotatory 90 degrees push rods that keep away from of eccentric post of pivot rotation, make the push rod slide and then drive the magnet splint and slide to the right side under the effort of first spring, magnet loses fixedly, the pivot is rotated simultaneously and is driven fixed station and reactor and put aside, thereby convenient to detach and change magnet, utilize the design of elasticity water absorption bag, need not make the device slope can be with liquid discharge, thereby can be fine control, avoid pouring out the liquid that contains the magnetism nanoparticle together, guarantee the degree of accuracy that detects.

Description

Magnetic nanoparticle detection device convenient to detect

Technical Field

The utility model relates to a SERS detection area, in particular to magnetism nanoparticle detection device convenient to detect.

Background

The surface enhanced Raman spectroscopy is an important analysis and detection technology, has the advantages of high sensitivity, even single molecule level detection and the like, and has great application potential in many fields, however, target molecules need to be adsorbed on the surface of a proper rough metal substrate to obtain SERS signals, so that the SERS effect depends on the distribution of the target molecules on the surface of the rough metal substrate to a certain extent, and the position of magnetic nanoparticles can be controlled by a traditional method in a way of adding magnets.

The existing detection device fixes a magnet on a base, the magnet can weaken influence detection by using magnetism for a long time, and therefore the magnet needs to be replaced, the magnet is located under a reactor and is difficult to replace, the existing detection device needs to pour out redundant liquid from the top, the liquid containing magnetic nanoparticles is easily poured out together due to direct pouring out, the deviation of Raman spectrum data is large, and therefore the magnetic nanoparticle detection device convenient to detect is provided.

SUMMERY OF THE UTILITY MODEL

An object of the utility model is to provide a magnetism nanoparticle detection device convenient to detect to solve the problem that proposes among the above-mentioned background art.

In order to achieve the above object, the utility model provides a following technical scheme: the utility model provides a magnetism nanoparticle detection device convenient to detect, includes the bottom plate, SERS substrate groove has been seted up to the top side of bottom plate, magnet mounting groove has been seted up on the top side inner wall in SERS substrate groove, has seted up the spacing groove on the top side inner wall in SERS substrate groove, has seted up same straight line groove on one side inner wall that spacing groove and magnet mounting groove are close to each other, and the pivot is installed to the spacing inslot rotation, and the top fixed mounting of pivot has the fixed station, and the bottom side fixed mounting of fixed station has the reactor, and the reactor sets up with the magnet mounting groove is corresponding in position.

Preferably, one side fixed mounting of pivot has the arc extrusion piece that is located the spacing inslot, and fixed mounting has the fixed link cover on the inner wall in sharp groove, and slidable mounting has the push rod in the fixed link cover, and the one end of push rod extends to in the magnet mounting groove and fixed mounting has the magnet splint, and the other end of push rod extends to the spacing inslot and contacts with one side of arc extrusion piece.

Preferably, the push rod is fixedly sleeved with a push rod sleeve, the push rod is sleeved with a first spring, and two ends of the first spring are respectively and fixedly installed on one side, close to each other, of the fixed rod sleeve and the push rod sleeve.

Preferably, one side of the fixed platform is fixedly provided with an elastic water absorption bag, two sides of the elastic water absorption bag are respectively and fixedly provided with a water absorption pipe and a water drainage pipe, and the water absorption pipe and the water drainage pipe are respectively provided with a one-way valve.

Preferably, an annular groove is formed in the inner wall of the limiting groove, an annular block is fixedly sleeved on the rotating shaft, and one side of the annular block extends into the annular groove.

Preferably, the top side fixed mounting of bottom plate has the backup pad, and the card hole has been seted up to one side of backup pad, and slidable mounting has the pin in the card hole, and outside the both ends of pin all extended to the card hole, the fixed stop collar that has cup jointed on the pin, cup jointed the second spring on the pin, and the both ends of second spring are fixed mounting respectively on one side that stop collar and backup pad are close to each other.

Preferably, one side of the rotating shaft is provided with a column groove, and one end of the pin extends into the column groove.

The utility model discloses a technological effect and advantage:

1. the utility model discloses it is rational in infrastructure, when this device of our long-time use, magnet can appear magnetism disappearance or the phenomenon that magnetism weakens, can bring adverse effect to our detection, so we will change the magnet that magnetism weakens, make the pin withdraw from the column casing through outwards pulling open the pin, rotatory pivot makes it rotate 90 degrees, the rotatory 90 degrees of eccentric post of pivot drive keep away from the push rod, make the push rod slide and then drive magnet splint and slide to the right side under the effort of first spring, magnet loses fixedly, the pivot is rotated simultaneously and is driven fixed station and reactor and put aside, thereby convenient to detach and change magnet.

2. Utilize the design of the elastic water absorption bag, when needs discharge unnecessary liquid from the reactor, through pressing the elastic water absorption bag, the elastic water absorption bag produces deformation, when loosening the elastic water absorption bag, the elastic water absorption bag inhales liquid through the pipe that absorbs water, press the elastic water absorption bag once more and make the liquid that is located the elastic water absorption bag pass through the drain pipe and discharge, thereby need not make the device slope can be with liquid discharge, thereby can be fine control, avoid pouring the liquid that contains the magnetism nanoparticle together, guarantee the degree of accuracy that detects.

Drawings

Fig. 1 is a schematic view of the three-dimensional structure of the present invention.

Fig. 2 is a schematic view of the front view structure of the present invention.

Fig. 3 is an enlarged schematic view of a portion a in fig. 1 according to the present invention.

Fig. 4 is an enlarged schematic structural diagram of the point B in fig. 2 according to the present invention.

FIG. 5 is a top view of the present invention with the rotating shaft, the arc-shaped extrusion block and the push rod connected

In the figure: 1. a base plate; 2. a magnet mounting groove; 3. a magnet clamp plate; 4. a push rod; 5. fixing the rod sleeve; 6. a limiting groove; 7. an arc-shaped extrusion block; 8. a linear groove; 9. a rotating shaft; 10. a drain pipe; 11. an elastic water absorption bag; 12. a suction pipe; 13. a fixed table; 14. a reactor; 15. a support plate; 16. a pin; 17. a second spring; 18. a column groove; 19. a first spring.

Detailed Description

The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative work belong to the protection scope of the present invention.

The utility model provides a magnetic nanoparticle detection device convenient to detect as shown in fig. 1-5, comprising a base plate 1, SERS substrate groove has been seted up to bottom plate 1's top side, magnet mounting groove 2 has been seted up on the top side inner wall in SERS substrate groove, spacing groove 6 has been seted up on the top side inner wall in SERS substrate groove, same straight line groove 8 has been seted up on the one side inner wall that spacing groove 6 and magnet mounting groove 2 are close to each other, pivot 9 is installed to 6 internal rotations in spacing groove, the top fixed mounting of pivot 9 has fixed station 13, the bottom side fixed mounting reactor 14 of fixed station 13, reactor 14 sets up with the position of magnet mounting groove 2 is corresponding, it can drive fixed station 13 and reactor 14 and rotate to rotate through pivot 9 rotation, thereby make reactor 14 put aside, be convenient for change magnet.

Further, in the above scheme, one side fixed mounting of pivot 9 has the arc extrusion piece 7 that is located spacing groove 6, fixed mounting has fixed rod cover 5 on the inner wall of straight line groove 8, slidable mounting has push rod 4 in the fixed rod cover 5, the one end of push rod 4 extends to in magnet mounting groove 2 and fixed mounting has magnet splint 3, the other end of push rod 4 extends to in spacing groove 6 and contacts with one side of arc extrusion piece 7, through the setting of magnet splint 3, can play the tight fixed effect of clamp to magnet.

Further, in the above scheme, a push rod sleeve is fixedly sleeved on the push rod 4, a first spring 19 is sleeved on the push rod 4, two ends of the first spring 19 are respectively and fixedly installed on one side of the fixed rod sleeve 5, which is close to the push rod sleeve, and through the arrangement of the first spring 19, a reaction force can be provided for the push rod 4, so that the push rod 4 can move rightwards.

Furthermore, in the above scheme, an elastic water absorption bag 11 is fixedly installed on one side of the fixing table 13, a water absorption pipe 12 and a water drainage pipe 10 are respectively and fixedly installed on two sides of the elastic water absorption bag 11, a one-way valve is respectively installed on the water absorption pipe 12 and the water drainage pipe 10, through the setting of the one-way valve, liquid can only flow along the directions of the water absorption pipe 12, the elastic water absorption bag 11 and the water drainage pipe 10, the elastic water absorption bag 11 deforms by pressing the elastic water absorption bag 11, when the elastic water absorption bag 11 is loosened, the elastic water absorption bag 11 absorbs the liquid through the water absorption pipe 12, the elastic water absorption bag 11 is pressed again, so that the liquid in the elastic water absorption bag 11 is discharged through the water drainage pipe 10, and the liquid can be discharged without inclining the device.

Furthermore, in the above scheme, an annular groove is formed in the inner wall of the limiting groove 6, the rotating shaft 9 is fixedly sleeved with the annular block, one side of the annular block extends into the annular groove, and the annular block can only rotate inside the annular block through the arrangement of the annular groove, so that the rotating shaft 9 can only rotate along the direction of the annular groove.

Further, in the above scheme, bottom plate 1's top side fixed mounting has backup pad 15, the card hole has been seted up to one side of backup pad 15, slidable mounting has pin 16 in the card hole, the both ends of pin 16 all extend to outside the card hole, the fixed stop collar that has cup jointed on the pin 16, the second spring 17 has been cup jointed on the pin 16, the both ends of second spring 17 are fixed mounting respectively on the one side that stop collar and backup pad 15 are close to each other, through the setting of second spring 17, when reactor 14 corresponds with the position of magnet, the position of pin 16 and post groove 18 is corresponding, make pin 16 extend to in the post groove 18 under the reaction force of second spring 17.

Furthermore, in the above scheme, a column groove 18 is formed in one side of the rotating shaft 9, one end of the pin 16 extends into the column groove 18, and the pin 16 is inserted into the column groove 18 through the arrangement of the column groove 18, so that the rotating shaft 9 can be limited.

This practical theory of operation:

when the magnetic nanoparticles are required to be detected, a magnet is placed in the magnet installation groove 2, the SERS substrate is inserted into the SERS substrate groove, then a magnetic nanoparticle solution and a solution of an object to be detected are injected from an inlet above the reactor 14, the magnetic nanoparticles and the magnet are mutually attracted after the magnetic nanoparticle solution and the solution of the object to be detected are mutually attracted in the reactor 14, the object to be detected and the magnetic nanoparticles are gathered on the SERS substrate right below the reactor 14, after a period of deposition, when the redundant liquid needs to be discharged from the reactor 14, the water suction pipe 12 is inserted to a proper depth in the reactor 14, the elastic water suction bag 11 is deformed by pressing the elastic water suction bag 11, when the elastic water suction bag 11 is loosened, the elastic water suction bag 11 sucks the liquid through the water suction pipe 12, the elastic water suction bag 11 is pressed again, so that the liquid in the elastic water suction bag 11 is discharged through the water discharge pipe 10, therefore, the liquid can be discharged without inclining the device, then the Raman spectrometer can be used for vertically irradiating from the right above the reactor 14 for detection, when the device is used for a long time, the phenomenon that the magnetism of the magnet disappears or the magnetism is weakened can occur, and the detection can be adversely affected, so people need to replace the magnet with weakened magnetism, the pin 16 is led to exit from the column groove 18 by pulling the pin 16 outwards, the second spring 17 is elastically deformed, at the moment, the rotating shaft 9 is relieved from the limit, the rotating shaft 9 is rotated for 90 degrees to drive the arc-shaped extrusion block 7 to rotate for 90 degrees, as the first spring 19 is in a compression state, the push rod 4 is enabled to slide towards the right side under the acting force of the first spring 19 to drive the magnet clamping plate 3 to slide towards the right side, the magnet is not fixed, and simultaneously, the rotating shaft 9 drives the fixing table 13 and the reactor 14 to move away, thereby convenient to detach and change magnet, when the change is accomplished, the counter-rotation pivot 9, when reactor 14 corresponds with the position of magnet, the position of pin 16 and post groove 18 is corresponding, make pin 16 extend to in post groove 18 under the reaction force of second spring 17, pivot 9 rotates simultaneously and drives arc extrusion piece 7 and rotate, and then extrudees push rod 4 and magnet splint 3 and make it slide left, and magnet is pressed from both sides tightly in magnet mounting groove 2, accomplishes fixedly this moment.

Finally, it should be noted that: although the present invention has been described in detail with reference to the foregoing embodiments, it will be apparent to those skilled in the art that modifications and variations can be made in the embodiments or in part of the technical features of the embodiments without departing from the spirit and the scope of the invention.

Claims

1. The utility model provides a magnetism nanoparticle detection device convenient to detect, includes bottom plate (1), the SERS substrate groove has been seted up to the top side of bottom plate (1), its characterized in that: magnet mounting groove (2) have been seted up on the top side inner wall in SERS substrate groove, spacing groove (6) have been seted up on the top side inner wall in SERS substrate groove, same straight line groove (8) have been seted up on one side inner wall that spacing groove (6) and magnet mounting groove (2) are close to each other, pivot (9) are installed to spacing groove (6) internal rotation, the top fixed mounting of pivot (9) has fixed station (13), the bottom side fixed mounting of fixed station (13) has reactor (14), reactor (14) and the corresponding setting in position of magnet mounting groove (2).

2. The magnetic nanoparticle detection device for facilitating detection as claimed in claim 1, wherein: one side fixed mounting of pivot (9) has arc extrusion piece (7) that is located spacing groove (6), and fixed mounting has fixed rod cover (5) on the inner wall of sharp groove (8), and slidable mounting has push rod (4) in fixed rod cover (5), and the one end of push rod (4) extends to in magnet mounting groove (2) and fixed mounting has magnet splint (3), and the other end of push rod (4) extends to in spacing groove (6) and contacts with one side of arc extrusion piece (7).

3. A magnetic nanoparticle detection device for facilitating detection according to claim 2, wherein: the push rod sleeve is fixedly sleeved on the push rod (4), the first spring (19) is sleeved on the push rod (4), and two ends of the first spring (19) are fixedly installed on one side, close to the fixed rod sleeve (5) and the push rod sleeve, of the fixed rod sleeve respectively.

4. The magnetic nanoparticle detection device for facilitating detection as claimed in claim 1, wherein: one side of the fixed platform (13) is fixedly provided with an elastic water absorption bag (11), two sides of the elastic water absorption bag (11) are respectively and fixedly provided with a water absorption pipe (12) and a water drainage pipe (10), and the water absorption pipe (12) and the water drainage pipe (10) are respectively provided with a one-way valve.

5. The magnetic nanoparticle detection device for facilitating detection as claimed in claim 1, wherein: an annular groove is formed in the inner wall of the limiting groove (6), an annular block is fixedly sleeved on the rotating shaft (9), and one side of the annular block extends into the annular groove.

6. The magnetic nanoparticle detection device for facilitating detection as claimed in claim 1, wherein: the top side fixed mounting of bottom plate (1) has backup pad (15), and the card hole has been seted up to one side of backup pad (15), and slidable mounting has pin (16) in the card hole, and the both ends of pin (16) all extend to outside the card hole, and the fixed stop collar that has cup jointed on pin (16), has cup jointed second spring (17) on pin (16), and the both ends difference fixed mounting of second spring (17) is on one side that stop collar and backup pad (15) are close to each other.

7. The magnetic nanoparticle detection device for facilitating detection as claimed in claim 1, wherein: one side of the rotating shaft (9) is provided with a column groove (18), and one end of the pin (16) extends into the column groove (18).