CN212764811U

CN212764811U - 3D bio-printer feed bucket

Info

Publication number: CN212764811U
Application number: CN202020102946.XU
Authority: CN
Inventors: 苗春光; 骆天治; 丁卫平; 武丹
Original assignee: Anhui Luohua Biotechnology Co ltd
Current assignee: Anhui Luohua Biotechnology Co ltd
Priority date: 2020-01-16
Filing date: 2020-01-16
Publication date: 2021-03-23
Anticipated expiration: 2030-01-16

Abstract

The utility model discloses a 3D bio-printer feed bucket, including casing I, the card lid that is the tubbiness, the card lid is provided with the motor, and casing I's inside axial position is provided with the (mixing) shaft, and the (mixing) shaft upper end pass the card lid and with the output transmission cooperation of motor, the lower extreme of (mixing) shaft is provided with the disc, and the disc is provided with the impeller blade with the side of being connected of (mixing) shaft, the lateral plate projection of impeller blade is the toper. The lower side of the disc is close to the bottom of the shell I, the size of the disc is equivalent to the diameter of the circumference of the shell I and approximately covers the bottom of the shell I, the disc can rotate axially under the action of the stirring shaft, the disc rotates and simultaneously rotates along with the impeller blades, and the impeller blades rotate to drive materials in the shell I to continuously roll upwards while rotating and stirring, so that the deposition effect of a mixed material is prevented.

Description

3D bio-printer feed bucket

Technical Field

The utility model belongs to the technical field of 3D biological printing, especially, relate to 3D biological printer feed bucket.

Background

In recent years, the rapid development of 3D printing technology opens up a new manufacturing and production model for industrial manufacturing. In the biological field, techniques such as bioprinting and three-dimensional controlled organization of cells are also applied. The technologies have the capability of operating single cells or single-component micro-size liquid drops, can accurately control the spatial position and distribution of an operation object, and have great significance for realizing the spatial position deposition of different cells and biological materials in the process of constructing large tissues and organs.

The 3D printing process of the tumor cells is to obtain more tumor cells by separating, extracting and culturing the tumor cells, then adding biological ink simulating the in-vivo environment to form a mixture, printing the mixture into tumor tissues by a 3D printer, and then carrying out drug testing on the tumor tissues to achieve the test effect of the drugs on the tumor tissues and obtain the pharmacological performance data of the drugs, thereby avoiding the unknown behavior of carrying out the drug testing on animals.

Three-dimensional printing biomaterial usually needs a feed bucket, holds the mixture that includes cell, biological ink and growth factor in the feed bucket, because biological ink is the gel class mostly, so the mixture viscosity in the compounding bucket is great, for the intensive mixing between each composition, needs mix each raw materials, and current agitating unit is difficult to carry out the compounding to compounding barrel head portion, and the raw materials deposits easily in the bottom of compounding bucket and causes the problem that barrel head density is bigger than normal. Therefore, the utility model discloses it is because agitating unit stirs inhomogeneous in the compounding bucket, the inhomogeneous problem of mixing between each composition of biological ink that leads to mainly to solve.

SUMMERY OF THE UTILITY MODEL

An object of the utility model is to provide a 3D bioprinter feed bucket, what mainly solved is because agitating unit stirs inhomogeneously in the compounding bucket, the inhomogeneous problem of mixing between the biological ink each composition that leads to.

In order to solve the technical problem, the utility model discloses a realize through following technical scheme:

the 3D biological printer feeding barrel comprises a barrel-shaped shell I, a clamping cover is arranged on the upper side of the shell I,

a motor is arranged above the clamping cover, the clamping cover is communicated with an air pressure pipe, and a discharge pipe is arranged on the side wall of the shell I;

the stirring shaft is arranged in the axial position in the shell I, the upper end of the stirring shaft penetrates through the clamping cover and is in transmission fit with the output end of the motor, a disc is arranged at the lower end of the stirring shaft, the stirring shaft is vertically fixedly connected with the center of the disc, impeller blades are arranged on the connecting side of the disc and the stirring shaft, and the projection of the side pieces of the impeller blades is conical.

Further, 3D bio-printer feed bucket, casing II has been cup jointed to casing I's outside, be provided with the spiral groove between casing I and the casing II, casing II's downside is provided with the inlet tube, casing II's upside is provided with the outlet pipe.

Further, 3D bio-printer feed bucket, it has water pump, heating device and temperature control device to establish ties between inlet tube and the outlet pipe.

Further, 3D bio-printer feed bucket, the casing I inner wall is provided with the bead.

Further, 3D bio-printer feed bucket, the card lid is provided with inlet pipe and atmospheric pressure balance pipe, inlet pipe and atmospheric pressure balance pipe are provided with the valve.

The utility model discloses following beneficial effect has:

the utility model discloses in, the downside of disc is close to bottom casing I, and the size of disc matches with casing I's circumference diameter, is close to cover in casing I's bottom, and the disc can the axis rotate under the effect of (mixing) shaft, and the rotation of following the impeller blade in the time of the disc pivoted, and the material in the impeller blade rotation drive casing I is continuous upwards rolling in rotatory stirring, prevents the deposit effect of mixture.

Of course, it is not necessary for any particular product to achieve all of the above-described advantages at the same time.

Drawings

In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the drawings used in the description of the embodiments will be briefly introduced below, and it is obvious that the drawings in the following description are only some embodiments of the present invention, and it is obvious for those skilled in the art that other drawings can be obtained according to these drawings without creative efforts.

FIG. 1: the utility model discloses the schematic structure.

FIG. 2: the utility model discloses (mixing) shaft structure picture.

In the drawings, the components represented by the respective reference numerals are listed below:

the device comprises a shell I1, a clamping cover 2, a motor 3, a pneumatic tube 21, a discharge tube 11, a stirring shaft 4, a disc 41, an impeller blade 42, a shell II 5, a spiral groove 51, a water inlet tube 52, a water outlet tube 53, a water pump 54, a heating device 55, a temperature control device 56, a convex rib 12, a feed tube 22, a pneumatic balance tube 23 and a valve 24.

Detailed Description

The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by a person of ordinary skill in the art without creative efforts belong to the protection scope of the present invention.

In the description of the present invention, it is to be understood that the terms "open hole", "upper", "lower", "thickness", "top", "middle", "length", "inner", "around", and the like, indicate positional or positional relationships, are merely for convenience in describing the present invention and to simplify the description, and do not indicate or imply that the components or elements referred to must have a particular orientation, be constructed and operated in a particular orientation, and therefore should not be construed as limiting the present invention.

As shown in fig. 1 and 2: the 3D biological printer feeding barrel comprises a barrel-shaped shell I1, a clamping cover 2 is arranged on the upper side of the shell I1,

the motor 3 is arranged above the clamping cover 2, the clamping cover 2 is communicated with an air pressure pipe 21, and a discharge pipe 11 is arranged on the side wall of the shell I1;

the inside axial position of casing I1 is provided with (mixing) shaft 4, the (mixing) shaft 4 upper end pass card lid 2 and with motor 3's output transmission cooperation, the lower extreme of (mixing) shaft 4 is provided with disc 41, the (mixing) shaft 4 and disc 41 central authorities vertical rigid coupling, disc 41 and (mixing) shaft 4's the side of being connected are provided with impeller blade 42, impeller blade 42's lateral piece projection is the toper.

As shown in fig. 1: casing II 5 has been cup jointed to casing I1's outside, be provided with spiral groove 51 between casing I1 and casing II 5, casing II 5's downside is provided with inlet tube 52, casing II 5's upside is provided with outlet pipe 53.

The utility model discloses in, casing II is the heat preservation shell, has held hot water in the casing II, and the groove of spiraling that wherein sets up is favorable to making the water that gets into rise by lower supreme spiraling, and casing I's heat absorption is more even, and the heat preservation effect is better.

As shown in fig. 1: a water pump 54, a heating device 55 and a temperature control device 56 are connected in series between the water inlet pipe 52 and the water outlet pipe 53.

Wherein, heating device is the heater strip, by temperature control device control heating, temperature control device perception temperature, artifical temperature regulation interval, the water pump is used for making rivers be the circulation attitude, improves energy utilization.

As shown in fig. 1: the inner wall of the shell I1 is provided with a convex rib 12.

The bead is the even rigid coupling in casing inside wall along casing I axis for the strip, plays the effect of vortex, when biological ink rotatory flow, is the torrent attitude under the effect of bead, is favorable to the mixing action.

As shown in fig. 1: the card cover 2 is provided with a feeding pipe 22 and a pneumatic balance pipe 23, and the feeding pipe 22 and the pneumatic balance pipe 23 are provided with a valve 24.

The feeding pipe is used for supplementing various raw materials, and when the raw materials are filled, the air pressure balancing pipe is opened to balance the air pressure inside and outside the shell I. The valve can open and close the air pressure balancing pipe and the feeding pipe simultaneously.

In the description herein, references to the description of "one embodiment," "an example," "a specific example," etc., mean that a particular feature, structure, material, or characteristic described in connection with the embodiment or example is included in at least one embodiment or example of the invention. In this specification, the schematic representations of the terms used above do not necessarily refer to the same embodiment or example. Furthermore, the particular features, structures, materials, or characteristics described may be combined in any suitable manner in any one or more embodiments or examples.

The preferred embodiments of the present invention disclosed above are intended only to help illustrate the present invention. The preferred embodiments are not intended to be exhaustive or to limit the invention to the precise embodiments disclosed. Obviously, many modifications and variations are possible in light of the above teaching. The embodiments were chosen and described in order to best explain the principles of the invention and its practical applications, to thereby enable others skilled in the art to best understand the invention for and utilize the invention. The present invention is limited only by the claims and their full scope and equivalents.

Claims

1.3D bioprinter feed bucket, including being tubbiness casing I (1), casing I (1) upside is provided with card lid (2), its characterized in that:

a motor (3) is arranged above the clamping cover (2), the clamping cover (2) is communicated with an air pressure pipe (21), and a discharge pipe (11) is arranged on the side wall of the shell I (1);

the inside axial position of casing I (1) is provided with (mixing) shaft (4), the (mixing) shaft (4) upper end pass card lid (2) and with the output transmission cooperation of motor (3), the lower extreme of (mixing) shaft (4) is provided with disc (41), perpendicular rigid coupling of (mixing) shaft (4) and disc (41) central authorities, disc (41) and the side of being connected of (mixing) shaft (4) are provided with impeller piece (42), the lateral plate projection of impeller piece (42) is the toper.

2. The 3D bioprinter supply tank of claim 1, wherein: casing II (5) has been cup jointed to the outside of casing I (1), be provided with between casing I (1) and casing II (5) spiral groove (51), the downside of casing II (5) is provided with inlet tube (52), the upside of casing II (5) is provided with outlet pipe (53).

3. The 3D bioprinter supply tank of claim 2, wherein: a water pump (54), a heating device (55) and a temperature control device (56) are connected in series between the water inlet pipe (52) and the water outlet pipe (53).

4. The 3D bioprinter supply tank of any one of claims 1-3, wherein: the inner wall of the shell I (1) is provided with a convex rib (12).

5. The 3D bioprinter supply tank of claim 1, wherein: the card lid (2) is provided with inlet pipe (22) and atmospheric pressure balance pipe (23), inlet pipe (22) and atmospheric pressure balance pipe (23) are provided with valve (24).