CN212586386U

CN212586386U - Multi-channel fluorescence immunoassay analyzer

Info

Publication number: CN212586386U
Application number: CN202022647806.3U
Authority: CN
Inventors: 何少贵; 乐宜萃; 张捷李; 白佳委; 胡啸; 汪大明
Original assignee: Anbio (xiamen) Products Inc; Xiamen Huaxia University
Current assignee: Anbio (xiamen) Products Inc; Xiamen Huaxia University
Priority date: 2020-11-16
Filing date: 2020-11-16
Publication date: 2021-02-23
Anticipated expiration: 2030-11-16

Abstract

The utility model provides a multichannel fluorescence immunoassay appearance, which comprises an outer shell, the shell is equipped with plug-in card mouth, control panel and useless bayonet socket, be equipped with in the shell and keep in the case, be used for waiting to detect reagent card and follow the bayonet socket department is sent into the card sending subassembly, the accredited testing organization of case that keep in the case, be used for waiting to detect reagent card and send into accredited testing organization's first transfer mechanism, be close to the useless card box of useless bayonet socket, be used for sending into the reagent card that will detect the second of useless card box transfers the mechanism, accredited testing organization includes that at least one detects position and portable setting and is in detect the test head of position top. The utility model discloses can treat automatically that detect reagent card carries out fluorescence immunoassay to can effectively improve detection efficiency.

Description

Multi-channel fluorescence immunoassay analyzer

Technical Field

The utility model relates to a fluorescence immunoassay technical field, in particular to multichannel fluorescence immunoassay appearance.

Background

The fluorescence immunoassay technology is used for measuring low-content bioactive compounds, such as proteins (enzymes, receptors, antibodies), hormones (steroids, thyroid hormones, phthalein hormones), drugs, microorganisms and the like, a protein chip is taken as one of biochips and becomes an important tool for researching proteins, the detection principle of the protein chip is the same as that of immunoassay, and can also be called chip immunoassay, the protein chip is roughly divided into three types, the first type is a chip formed by a protein microarray, the second type is a microfluidic chip based on various microstructures, and the third type is a suspension chip combined with microsphere coding and flow detection. Most of the existing fluorescence immunoassay devices are single-channel, and only one reagent card can be used for detection, so that the detection efficiency is low.

SUMMERY OF THE UTILITY MODEL

The problem of detection efficiency low to current fluorescence immunoassay device exists, the utility model provides a multichannel fluorescence immunoassay appearance.

For realizing the purpose of the utility model, the utility model adopts the technical proposal that:

the utility model provides a multichannel fluorescence immunoassay appearance, includes the shell, the shell is equipped with plug-in card mouth, control panel and useless bayonet socket, be equipped with in the shell and hold in the palm the case, be used for with wait to detect reagent card follow the bayonet socket is sent into hold in the palm send card subassembly, accredited testing organization, be used for sending into wait to detect reagent card the accredited testing organization first transfer mechanism, be close to the useless card box of useless bayonet socket, be used for sending into the reagent card that detects the completion the second transfer mechanism of useless card box, accredited testing organization includes that at least one detects the position and portable setting is in detect the test head of position top.

Preferably, the temporary storage box is equipped with curb plate, a plurality of setting and is in the baffle of curb plate one side and drive the actuating mechanism that the curb plate reciprocated, the baffle equidistant setting and form the card slot that is used for placing the test agent card of waiting to examine between the baffle, card slot with the card slot is corresponding.

Preferably, actuating mechanism includes first action wheel, first driven wheel, connects the first synchronous belt of first action wheel and first driven wheel and connection the first motor of first action wheel, be equipped with the transmission piece on the first synchronous belt, the transmission piece with curb plate fixed connection.

Preferably, the card feeding assembly comprises a second motor and a roller assembly, the roller assembly comprises a driving roller and a driven roller, the driving wheel is connected with the first motor, the driving wheel and the driven roller are horizontally arranged oppositely, and the distance between the driving wheel and the driven roller is equal to the width of the reagent card to be detected.

Preferably, the bottom of the roller assembly is provided with a transmission gear set, and the transmission gear set is arranged between the driving roller and the driven roller.

Preferably, first transfer mechanism includes second action wheel, second follower, connects the second hold-in range and the connection of second action wheel and second follower the third motor of second action wheel, be equipped with on the second hold-in range and be used for driving and wait to detect the first of reagent card removal and scrape and collude, first scraping is colluded and is located the temporary storage case front end.

Preferably, the second transfer mechanism includes a left and right transfer unit for moving the reagent card after completion of the test to the rear end of the waste cartridge, and a front and rear transfer unit for feeding the reagent card after completion of the test into the waste cartridge.

Preferably, it includes third action wheel, third driven wheel, connects to control the transfer module the third hold-in range and the connection of third action wheel and third driven wheel the fourth motor of third action wheel, it is in to detect the fixed setting in position the third hold-in range.

Preferably, the front and back transfer assembly comprises a fourth driving wheel, a fourth driven wheel and a fourth synchronous belt and a fifth motor, the fourth synchronous belt is connected with the fourth driving wheel and the fourth driven wheel, the fourth synchronous belt is provided with a reagent card used for driving the detection completion and sending the reagent card into the waste card box, and the second scraping hook is arranged on the waste card box. The second scraping hook is positioned at the rear end of the waste card box.

Preferably, a moving mechanism is arranged at the bottom of the waste card box.

The utility model discloses a multichannel fluorescence immunoassay appearance's beneficial effect as follows:

the utility model discloses be equipped with the temporary storage case and can be used for depositing the reagent card that detects, the reagent card in the temporary storage case can be sent into detection area under the effect of transmitting mechanism to detection area is equipped with a plurality of detection positions and can detects a plurality of reagent cards simultaneously, transmits to useless card box after the detection is accomplished, and whole process can go on automatically, has effectively improved detection efficiency.

Drawings

FIG. 1: the external structure of the utility model is shown schematically;

FIG. 2: the internal structure of the utility model is shown schematically;

in the figure: 10. a housing; 20. a card inserting opening; 30. a control panel; 40. a waste bayonet; 50. a temporary storage box; 60. a card feeding assembly; 70. a testing mechanism; 71. detecting a bit; 72. a test head; 80. a first transfer mechanism; 81. a first scraping hook; 90. a waste card box; 100. a second transfer mechanism; 101. a left and right transfer assembly; 102. a front and rear transfer assembly; 1021. and a second scraping hook.

Detailed Description

The existing fluorescence immunoassay device has the problem of low detection efficiency. Therefore, the present invention provides a new solution, and for a clearer representation, the present invention will be described in detail with reference to the accompanying drawings.

Referring to fig. 1-2, a multi-channel fluorescence immunoassay analyzer comprises a housing 10, wherein the housing 10 is provided with a card insertion opening 20, a control panel 30 and a waste card opening 40, a temporary storage box 50, a card feeding assembly 60 for feeding a test reagent card to be detected into the temporary storage box 50 from the card insertion opening 20, a testing mechanism 70, a first transfer mechanism 80 for feeding the test reagent card to be detected into the testing mechanism 70, a waste card box 90 close to the waste card opening 40, and a second transfer mechanism 100 for feeding the detected reagent card into the waste card box 90, the testing mechanism 70 comprises at least one detection position 71 and a testing head 72 movably arranged above the detection position 71, and one end of the testing head 72 is connected with a driving part for driving the testing head 72 to move.

In this embodiment, the height positions of the card insertion slot 20, the card feeding unit 60, and the detection position 71 correspond to each other, and the waste cartridge 90 can be taken out from the waste insertion slot 40. The detection position 71 is provided with a detection plate, three clamping positions are arranged on the detection plate, and three groups of reagent cards to be detected can be detected simultaneously.

The housing 10 is provided with a support plate and a plurality of support frames for mounting or erecting the card feeding assembly 60, the testing framework, the first transfer mechanism 80, the waste card box 90 and the second transfer mechanism 100.

Temporary storage box 50 is equipped with curb plate, a plurality of setting and is in the baffle and the drive of curb plate one side the actuating mechanism that the curb plate reciprocated, the baffle equidistant setting and form the card slot that is used for placing the test agent card of waiting to examine between the baffle, card slot with card slot 20 is corresponding. The card insertion opening 20 and the waste card insertion opening 40 are arranged on the front end face of the shell 10, and the internal temporary storage box 50, the testing mechanism 70 and the waste card box 90 are arranged clockwise and square.

The driving mechanism comprises a first driving wheel, a first driven wheel, a first synchronous belt and a first motor, the first synchronous belt is connected with the first driving wheel and the first driven wheel, a transmission block is arranged on the first synchronous belt, and the transmission block is fixedly connected with the side plates.

Card feeding assembly 60 includes second motor and roller assembly, roller assembly includes initiative gyro wheel and driven gyro wheel, the action wheel is connected first motor, the action wheel with the driven wheel level sets up relatively, the action wheel with interval between the driven wheel equals with the width of waiting to detect reagent card.

And a transmission gear set is arranged at the bottom of the roller component and is arranged between the driving roller and the driven roller. The synchronism of the rotation of the driving roller and the driven roller can be ensured, and the inserted reagent card can be stably conveyed into the temporary storage box 50.

First transfer mechanism 80 includes second action wheel, second driven wheel, connects the second hold-in range and the connection of second action wheel and second driven wheel the third motor of second action wheel, be equipped with on the second hold-in range and be used for driving the first hook 81 of scraping that detects the removal of detection reagent card, first scrape hook 81 and be located the temporary storage case 50 front end. The thickness of the first scraping hook 81 corresponds to the thickness of the reagent card to be detected, and the first scraping hook can move between the partition plates of the temporary storage box 50 to ensure that the reagent card to be detected can be pushed to enter the detection position 71.

The second transfer mechanism 100 includes a left-right transfer unit 101 for moving the reagent card after completion of the test to the rear end of the waste cartridge 90, and a front-rear transfer unit 102 for feeding the reagent card after completion of the test into the waste cartridge 90.

The left and right transfer assembly 101 comprises a third driving wheel, a third driven wheel, a third synchronous belt connected with the third driving wheel and the third driven wheel and a fourth motor connected with the third driving wheel, and the detection position 71 is fixedly arranged on the third synchronous belt.

The front and rear transfer assembly 102 comprises a fourth driving wheel, a fourth driven wheel, a fourth synchronous belt and a fifth motor, the fourth synchronous belt is connected with the fourth driving wheel and the fourth driven wheel, the fifth motor is used for driving a reagent card after detection is completed to be sent into the fourth synchronous belt, and the second scraping hook 1021 of the waste card box 90 is arranged on the fourth synchronous belt. The second scraping hook 1021 is positioned at the rear end of the waste card box 90.

Waste card box 90 bottom is equipped with moving mechanism, moving mechanism drives and removes about waste card box 90 to the stack can be put waste card neatly, is favorable to the space in the rational utilization waste card box 90.

In the present embodiment, a synchronous wheel and a synchronous belt are used to cooperate to realize the relative movement transfer action, and in other embodiments, other mechanisms, such as an air cylinder, may be used instead.

In this embodiment, a power supply and a main control board are disposed in the housing 10, and the control panel 30, the temporary storage box 50, the card feeding assembly 60, the testing mechanism 70, the first transferring mechanism 80, and the second transferring mechanism 100 are all connected to the main control board, and the control panel 30-bit touch screen of this embodiment can control the start and stop of the fluorescence immunoassay test through the control panel 30, and can perform parameter setting on the detection program.

The utility model discloses a brief work flow as follows:

the reagent card to be detected is inserted into the card inserting opening 20, the motor of the card feeding assembly 60 drives the roller to rotate so as to clamp the reagent card to be detected and enter the temporary storage box 50, the temporary storage box 50 moves up and down to adjust the vacancy position, the motor of the first transfer mechanism 80 drives the first scraping hook 81 to push the reagent card to be detected stored in the temporary storage box 50 into the detection position 71, the detected waste card is firstly transferred to the rear end of the waste card box 90 rightwards through the left and right transfer assemblies 101 of the second transfer mechanism 100, and then the front and rear transfer assemblies 102 drive the second scraping hook 1021 to push the waste card into the waste card box 90, so that the fluorescence immunoassay test is completed. The waste card box 90 receives a waste card and then moves to place the waste card in order to complete the stacking of the waste card, and after the waste card box 90 is fully loaded, the waste card box is pushed out of the housing 10 to take out the waste card.

The utility model discloses can treat automatically that detect reagent card carries out fluorescence immunoassay to can effectively improve detection efficiency.

The above embodiments are only used for explaining the technical solution of the present invention and not for limiting the same, and although the above embodiments are specific to the present invention, it should be understood by those skilled in the art that the present invention can be modified or replaced with equivalents without departing from the spirit and scope of the present invention, which should be covered by the claims of the present invention.

Claims

1. A multi-channel fluorescence immunoassay analyzer is characterized in that: the test device comprises an outer shell, the shell is equipped with plug-in card mouth, control panel and useless bayonet socket, be equipped with in the shell and temporarily deposit the case, be used for waiting to detect reagent card follow the bayonet socket department sends into send card subassembly, accredited testing organization, be used for sending into waiting to detect reagent card the accredited testing organization's first transfer mechanism, be close to useless bayonet socket useless card box, be used for sending into the reagent card that detects the card that finishes the second transfer mechanism of useless card box, accredited testing organization includes that at least one detects the position and portable setting is in detect the test head of position top.

2. The multi-channel fluoroimmunoassay analyzer of claim 1, wherein: the temporary storage box is provided with a side plate, a plurality of baffles arranged on one side of the side plate and a driving mechanism for driving the side plate to move up and down, the baffles are arranged at equal intervals, a card slot for placing a test agent card to be tested is formed between the baffles, and the card slot corresponds to the card slot.

3. The multi-channel fluoroimmunoassay analyzer of claim 2, wherein: the driving mechanism comprises a first driving wheel, a first driven wheel, a first synchronous belt and a first motor, the first synchronous belt is connected with the first driving wheel and the first driven wheel, a transmission block is arranged on the first synchronous belt, and the transmission block is fixedly connected with the side plates.

4. The multi-channel fluoroimmunoassay analyzer of claim 1, wherein: the card feeding assembly comprises a second motor and a roller assembly, the roller assembly comprises a driving roller and a driven roller, the driving wheel is connected with the first motor, the driving wheel and the driven roller are horizontally arranged oppositely, and the distance between the driving wheel and the driven roller is equal to the width of a reagent card to be detected.

5. The multi-channel fluoroimmunoassay analyzer of claim 4, wherein: and a transmission gear set is arranged at the bottom of the roller component and is arranged between the driving roller and the driven roller.

6. The multi-channel fluoroimmunoassay analyzer of claim 1, wherein: first transfer mechanism includes second action wheel, second follower, connects the second hold-in range and the connection of second action wheel and second follower the third motor of second action wheel, be equipped with on the second hold-in range and be used for driving the first hook of scraping that detects the removal of detection reagent card, first scrape the hook and be located the case front end of keeping in.

7. The multi-channel fluoroimmunoassay analyzer of claim 1, wherein: the second transfer mechanism comprises a left-right transfer component used for moving the reagent card after detection to the rear end of the waste card box and a front-back transfer component used for sending the reagent card after detection into the waste card box.

8. The multi-channel fluoroimmunoassay analyzer of claim 7, wherein: the left and right transfer assembly comprises a third driving wheel, a third driven wheel, a third synchronous belt connected with the third driving wheel and the third driven wheel and a fourth motor connected with the third driving wheel, and the detection position is fixedly arranged on the third synchronous belt.

9. The multi-channel fluoroimmunoassay analyzer of claim 7, wherein: the front and back transfer assembly comprises a fourth driving wheel, a fourth driven wheel and a fourth synchronous belt and is connected with the fourth driving wheel and the fourth driven wheel, a fifth motor of the fourth driving wheel is arranged on the fourth synchronous belt, the fourth synchronous belt is provided with a reagent card used for driving detection completion and sending the reagent card into the waste card box, the second of the waste card box is scraped and hooked, and the second is scraped and hooked to the rear end of the waste card box.

10. The multi-channel fluoroimmunoassay analyzer of claim 1, wherein: and a moving mechanism is arranged at the bottom of the waste card box.