CN212586294U - Electromechanical integrated sample loading device and capillary electrophoresis apparatus - Google Patents
Electromechanical integrated sample loading device and capillary electrophoresis apparatus Download PDFInfo
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- CN212586294U CN212586294U CN202021333141.2U CN202021333141U CN212586294U CN 212586294 U CN212586294 U CN 212586294U CN 202021333141 U CN202021333141 U CN 202021333141U CN 212586294 U CN212586294 U CN 212586294U
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Abstract
The utility model discloses a mechanical and electrical integral type device of getting ready, wherein, this mechanical and electrical integral type device of getting ready includes mounting plate and sets up electrical control board, sample platform and the three-dimensional removal subassembly on mounting plate, and the sample platform is used for holding sample and reaction liquid, and the sample platform sets up on the three-dimensional removal subassembly, and the three-dimensional removal subassembly can realize the removal of sample platform on three-dimensional side, electrical control board and three-dimensional removal subassembly electrical connection to control the removal of three-dimensional removal subassembly. The utility model also discloses a capillary electrophoresis apparatus. The utility model discloses an electric control panel with the device of getting ready assembles integratively with the mechanical part of the device of getting ready for the device of getting ready can carry out independent production, debugging and technical inspection outside the complete machine, and the module of getting ready can reach technical requirement through simple debugging on the complete machine like this, and then can effectively improve the production efficiency of capillary electrophoresis appearance.
Description
Technical Field
The utility model relates to a biochemical detection area especially relates to a capillary electrophoresis apparatus of appearance device and applied this appearance device of going up is gone up to electromechanical integral type.
Background
Capillary electrophoresis detection technology is a main analysis technology at present, and is widely applied to various fields by virtue of the characteristics of high efficiency, sensitivity, rapidness, simple equipment, strong applicability and the like. The method is a novel liquid phase separation technology which takes a capillary tube as a separation channel and takes a high-voltage direct-current electric field as a driving force. Capillary electrophoresis, which in fact comprises electrophoresis, chromatography and their cross-over, allows analytical chemistry to go from microliter levels to nanoliter levels and enables single cell analysis, and even single molecule analysis.
In current capillary electrophoresis product, can design a total electrical control box, the electrical control board of the module of getting ready can install total electrical control box, and the module of getting ready can't carry out independent production, debugging and technical inspection outside the complete machine, need install it after the module of getting ready production and carry out complicated debugging and inspection on the complete machine, therefore lead to capillary electrophoresis product production efficiency lower.
SUMMERY OF THE UTILITY MODEL
An object of the utility model is to provide a can carry out independent production, debugging and technical inspection's electromechanical integral type appearance loading device and capillary electrophoresis apparatus outside the complete machine.
In order to achieve the above object, the utility model discloses a concrete technical scheme who goes up appearance device and capillary electrophoresis apparatus is:
the utility model provides an electromechanical integral type device of getting ready, wherein, includes mounting plate and sets up electric control board, sample platform and the three-dimensional subassembly that moves on mounting plate, and the sample platform is used for holding sample and reaction liquid, and the sample platform sets up on the three-dimensional subassembly that moves, and the three-dimensional subassembly that moves can realize the removal of sample platform in three-dimensional direction, and electric control board and three-dimensional removal subassembly electrical connection to the removal of control three-dimensional removal subassembly.
Further, the electric control board comprises a single chip microcomputer, and a power interface, a bus interface and a control port which are connected with the single chip microcomputer, wherein the power interface is used for connecting a power supply, the bus interface is used for being electrically connected with an external device, and the control port is used for being electrically connected with the three-dimensional moving assembly.
Further, the bus interface comprises at least one of a CAN bus interface, an RS232 bus interface and an RS485 bus interface.
Furthermore, a wiring groove is formed in the installation bottom plate, and an electric connecting wire between the control port and the three-dimensional moving assembly is placed in the wiring groove.
Furthermore, the three-dimensional moving assembly comprises a first direction moving unit, a second direction moving unit and a third direction moving unit, the sample stage is arranged on the third direction moving unit, the third direction moving unit is arranged on the second direction moving unit, the second direction moving unit is arranged on the first direction moving unit, the first direction moving unit is arranged on the installation bottom plate, and the sample stage can move in the three-dimensional direction through the first direction moving unit, the second direction moving unit and the third direction moving unit.
Further, the first direction movement unit comprises a first motor, a first belt and a first slide rail, the first slide rail is fixedly arranged on the mounting base plate, the first motor is connected with the first belt, a first bearing table is fixedly arranged on the first belt, a first sliding block is fixedly arranged on the first bearing table, and the first sliding block is arranged on the first slide rail in a sliding mode.
Furthermore, the second direction movement unit comprises a second motor, a second belt and a second slide rail, the second slide rail is fixedly arranged on the first bearing table, the second motor is connected with the second belt, the second bearing table is fixedly arranged on the second belt, a second slide block is fixedly arranged on the second bearing table, and the second slide block is arranged on the second slide rail in a sliding manner.
Furthermore, the third direction movement unit comprises a third motor, the third motor is fixedly arranged on the sample platform, a motor shaft of the third motor is connected with the connecting support, the connecting support is fixedly arranged on the second bearing platform, a third sliding rail is arranged on the second bearing platform, a third sliding block is fixedly arranged on the sample platform, and the third sliding block is arranged on the third sliding rail in a sliding manner.
Further, the extending directions of the first slide rail, the second slide rail and the third slide rail are mutually vertical.
A capillary electrophoresis apparatus, comprising any one of the above mechatronic sample loading devices.
The utility model discloses a go up appearance device and capillary electrophoresis apparatus has following advantage: the electrical control board of the sample loading device and the mechanical part of the sample loading device are assembled into a whole to form the mechanical-electrical integrated sample loading device, so that technicians can independently produce, debug and inspect the performance of the sample loading module by means of a PC (personal computer) or a notebook computer and the like. Furthermore, after the sample loading module passing the performance test is installed on the whole capillary electrophoresis apparatus, the technical requirements can be met through simple debugging on the whole capillary electrophoresis apparatus, so that the production efficiency of the capillary electrophoresis apparatus can be effectively improved.
Drawings
Fig. 1 is a first perspective view of a sample loading device of the present invention;
fig. 2 is a second perspective view of the sample loading device of the present invention;
fig. 3 is a first perspective view of a three-dimensional moving assembly in a sample loading device according to the present invention;
fig. 4 is a second perspective view of the three-dimensional moving assembly in the sample loading device of the present invention;
fig. 5 is a first perspective view of a first direction moving unit in the three-dimensional moving assembly of the present invention;
fig. 6 is a second perspective view of the first direction moving unit in the three-dimensional moving assembly of the present invention;
fig. 7 is a first perspective view of a second directional movement unit in the three-dimensional moving assembly of the present invention;
fig. 8 is a second perspective view of a second directional movement unit in the three-dimensional moving assembly of the present invention;
fig. 9 is a first perspective view of a third directional motion unit in the three-dimensional moving assembly of the present invention;
fig. 10 is a second perspective view of a third directional motion unit in the three-dimensional moving assembly according to the present invention.
Detailed Description
For better understanding, the purpose, structure and function of the present invention are described in detail below with reference to the accompanying drawings.
As shown in fig. 1 to 10, the sample loading device of the present invention includes a sample stage 100, a three-dimensional moving assembly 200, an electrical control board 300, and a mounting plate 400, wherein the electrical control board 300, the sample stage 100, and the three-dimensional moving assembly 200 are all disposed on the mounting plate 400. Wherein the sample stage 100 is disposed on the three-dimensional moving assembly 200, the three-dimensional moving assembly 200 can realize the movement of the sample stage 100 in the three-dimensional direction, the electrical control board 300 is electrically connected to the three-dimensional moving assembly 200, and specifically, the electrical control board 300 is electrically connected to the driving part of the three-dimensional moving assembly 200 to control the movement of the three-dimensional moving assembly 200. It should be noted that the utility model provides an electromechanical integral type sample loading device can use on automatic check out test set such as capillary electrophoresis apparatus to realize check out test set's automatic sample loading.
Specifically, the sample stage 100 is provided with a first receiving groove 110 and a second receiving groove 120, wherein a sample plate can be placed in the first receiving groove 110, and the sample plate can be a 96-well plate, an eight-row tube or a centrifuge tube, and the like, and is used for containing a sample to be detected; the reaction liquid tank can be placed in the second receiving tank 120, and the reaction liquid tank includes two chambers, where the first chamber is used to contain cathode buffer, the second chamber is used to contain pure water, the cathode buffer can provide a buffer system and a conductive medium for the electrophoresis process, and the pure water can be used to discharge waste glue and clean the capillary.
Therefore, in the electrophoresis process, waste glue can be firstly discharged in pure water of a reaction liquid tank, then sample introduction is carried out in a sample plate by means of potential difference, and finally electrophoresis is carried out in cathode buffer solution, wherein the sample plate is required to be washed in the pure water when different tanks are switched, and the three-dimensional movement of the sample table 100 is controlled by the three-dimensional moving assembly 200 so as to complete the switching among the different tanks. In addition, optionally, in the electrophoresis process, the waste gel may be first discharged from pure water in the reaction liquid tank, then pre-electrophoresis is performed in the cathode buffer solution in the reaction liquid tank, then sample injection is performed in the sample plate by means of potential difference, and finally electrophoresis is performed in the cathode buffer solution. Of course, it is understood that different operation procedures can be selected according to different situations, and the above is only a preferred example and is not limited in detail.
Further, the three-dimensional moving assembly 200 includes a first direction moving unit on which the sample stage 100 is disposed, a second direction moving unit on which the third direction moving unit is disposed, and a third direction moving unit on which the second direction moving unit is disposed and the first direction moving unit on which the first direction moving unit is disposed on the installation base plate 400.
Preferably, the first direction moving unit in this embodiment may realize the movement of the sample stage 100 in the X-axis direction, the second direction moving unit may realize the movement of the sample stage 100 in the Y-axis direction, and the third direction moving unit may realize the movement of the sample stage 100 in the Z-axis direction. Thus, the movement of the specimen stage 100 in the three-dimensional direction can be achieved by the first direction moving unit, the second direction moving unit, and the third direction moving unit.
Further, the first direction moving unit includes a first motor 211, a first belt 212 and a first slide rail 213, wherein the first slide rail 213 is fixedly disposed on the mounting base plate 400, the first motor 211 is connected to the first belt 212, the first belt 212 is fixedly disposed with a first bearing table 214, the first bearing table 214 is fixedly disposed with a first sliding block 215, and the first sliding block 215 is slidably disposed on the first slide rail 213. Therefore, the first motor 211 can drive the first belt 212 to rotate, and when the first belt 212 rotates, the first loading platform 214 can be synchronously driven to move, so as to drive the first sliding block 215 to move along the first sliding rail 213, so as to realize the movement of the sample platform 100 in the X-axis direction.
Further, the second direction moving unit includes a second motor 221, a second belt 222 and a second slide rail 223, wherein the second slide rail 223 is fixedly disposed on the first bearing platform 214, the second motor 221 is connected to the second belt 222, the second belt 222 is fixedly disposed with a second bearing platform 224, the second bearing platform 224 is fixedly disposed with a second sliding block 225, and the second sliding block 225 is slidably disposed on the second slide rail 223. Therefore, the second motor 221 can drive the second belt 222 to rotate, and when the second belt 222 rotates, the second bearing platform 224 can be synchronously driven to move, so as to drive the second slider 225 to move along the second slide rail 223, so as to realize the movement of the sample platform 100 in the Y-axis direction.
Further, the third direction moving unit includes a third motor 231, wherein the third motor 231 is fixedly disposed on the sample stage 100, a motor shaft of the third motor 231 is connected to the connecting bracket 232, the connecting bracket 232 is fixedly disposed on the second bearing stage 224, the second bearing stage 224 is provided with a third slide rail 233, the sample stage 100 is fixedly provided with a third slide block 234, and the third slide block 234 is slidably disposed on the third slide rail 233. Thus, the extension of the motor shaft of the third motor 231 can move the sample stage 100 away from the connecting bracket 232, so that the third slide 234 on the sample stage 100 moves along the third slide rail 233 on the second bearing platform 224, thereby realizing the movement of the sample stage 100 in the Z-axis direction.
In general, the sample stage 100 is fixedly connected to the third slide block 234, the third slide block 234 is slidably connected to the third slide rail 233, and the third slide rail 233 is fixedly connected to the second loading stage 232; the second bearing table 224 is fixedly connected with a second sliding block 225, the second sliding block 225 is slidably connected with a second sliding rail 223, and the second sliding rail 223 is fixedly connected with the first bearing table 214; the first bearing platform 214 is fixedly connected with the first sliding block 215, the first sliding block 215 is slidably connected with the first sliding rail 213, and the first sliding rail 213 is fixedly arranged on the installation base plate 400.
Further, the extending directions of the first slide rail 213, the second slide rail 223 and the third slide rail 233 are perpendicular to each other. Therefore, the motor shaft of the third motor 231 extends or retracts to drive the sample stage 100 to reciprocate in the extending direction of the third slide rail 233; the second motor 221 drives the second belt 222 to rotate, so as to drive the sample stage 100 to reciprocate in the extending direction of the second slide rail 223; the first motor 211 drives the first belt 212 to rotate, so as to drive the sample stage 100 to move reciprocally in the extending direction of the first slide rail 213.
The first motor 211, the second motor 221, and the third motor 231 may be implemented by stepping motors, direct current motors, or servo motors. Specifically, the first motor 211, the second motor 221 and the third motor 231 of the three-dimensional moving assembly 200 are connected with the control port 340 of the electrical control board 300 through electrical connection lines. Preferably, the installation bottom plate 400 is provided with a wiring groove 500, and the electrical connection lines are placed in the wiring groove 500, so that the electrical connection lines are prevented from being placed in a mess, the installation space is saved, and the integration of the device is improved.
Further, the electric control board 300 includes a single chip 310, and a power interface 320, a bus interface 330 and a control port 340 connected to the single chip 310, wherein the power interface 320 is used for connecting a power source, the bus interface 330 is used for electrically connecting to an external device, and the control port 340 is used for electrically connecting to the three-dimensional moving assembly 200. In this embodiment, the electrical control part and the mechanical part are integrated, the electrical control board 300 and the capillary electrophoresis apparatus are connected by the bus and the power source only through the power source interface 320 and the bus interface 330, and the integrated mechanical and electrical loading device enables a technician to debug and test the module independently through the bus interface 330 on the electrical control board 300 by means of a notebook computer or a PC.
The bus interface 330 may include at least one of a CAN bus interface, an RS232 bus interface, and an RS485 bus interface. The bus interface 330 may also include other bus interfaces, which are only preferred examples and are not limited in particular. In this embodiment, the number of bus interfaces provided by the electrical control board 300 can be set as required, and the present invention is not limited to this. In one embodiment, 2 identical bus interfaces may be provided on the electrical control board 300 to facilitate the serial connection of multiple electrical control boards 300.
The utility model also provides a capillary electrophoresis apparatus, including the show electromechanical integral type of above-mentioned embodiment device of getting ready. Through the embodiment, it can be understood that other functional modules in the capillary electrophoresis apparatus or other biological instruments can also be realized in an electromechanical integration manner so as to perform independent production, debugging and inspection.
The utility model discloses a go up appearance device and capillary electrophoresis apparatus assembles into an organic whole through the mechanical part with the electrical control board of going up the appearance device and the appearance device of going up, constitutes mechatronic appearance device of going up for the technical staff can carry out independent production, debugging and performance inspection to the appearance module of going up with the help of PC or notebook computer etc.. Furthermore, after the sample loading module passing the performance test is installed on the whole capillary electrophoresis apparatus, the technical requirements can be met through simple debugging on the whole capillary electrophoresis apparatus, so that the production efficiency of the capillary electrophoresis apparatus can be effectively improved.
The present invention has been further described with reference to specific embodiments, but it should be understood that the specific description herein should not be construed as limiting the spirit and scope of the present invention, and that various modifications to the above-described embodiments, which would occur to persons skilled in the art after reading this specification, are within the scope of the present invention.
Claims (10)
1. The utility model provides a mechanical and electrical integration type sample loading device which characterized in that, includes mounting plate and sets up electrical control board, sample platform and the three-dimensional subassembly that sets up on mounting plate, and the sample platform is used for holding sample and reaction liquid, and the sample platform sets up on the three-dimensional subassembly that removes, and the three-dimensional subassembly that removes can realize the removal of sample platform in three-dimensional direction, and electrical control board and three-dimensional removal subassembly electrical connection to the removal of control three-dimensional removal subassembly.
2. The mechanical and electrical integrated sample loading device as claimed in claim 1, wherein the electrical control board comprises a single chip microcomputer, and a power interface, a bus interface and a control port which are connected with the single chip microcomputer, the power interface is used for connecting a power supply, the bus interface is used for electrically connecting with an external device, and the control port is used for electrically connecting with the three-dimensional moving assembly.
3. The electro-mechanical integrated sample loading device of claim 2, wherein the bus interface comprises at least one of a CAN bus interface, an RS232 bus interface, and an RS485 bus interface.
4. The electromechanical integrated sample loading device according to claim 2, wherein a wiring groove is arranged on the mounting bottom plate, and an electrical connection line between the control port and the three-dimensional moving assembly is placed in the wiring groove.
5. The electromechanical integrated sample loading device according to any one of claims 1 to 4, wherein the three-dimensional moving assembly comprises a first direction moving unit, a second direction moving unit and a third direction moving unit, the sample stage is arranged on the third direction moving unit, the third direction moving unit is arranged on the second direction moving unit, the second direction moving unit is arranged on the first direction moving unit, the first direction moving unit is arranged on the installation bottom plate, and the movement of the sample stage in the three-dimensional direction can be realized through the first direction moving unit, the second direction moving unit and the third direction moving unit.
6. The mechanical and electrical integrated sample loading device according to claim 5, wherein the first direction moving unit comprises a first motor, a first belt and a first slide rail, the first slide rail is fixedly arranged on the mounting base plate, the first motor is connected with the first belt, a first bearing table is fixedly arranged on the first belt, a first slide block is fixedly arranged on the first bearing table, and the first slide block is slidably arranged on the first slide rail.
7. The electromechanical integrated sample loading device according to claim 6, wherein the second direction moving unit comprises a second motor, a second belt and a second slide rail, the second slide rail is fixedly disposed on the first bearing platform, the second motor is connected to the second belt, the second bearing platform is fixedly disposed on the second belt, a second slide block is fixedly disposed on the second bearing platform, and the second slide block is slidably disposed on the second slide rail.
8. The electromechanical integrated sample loading device according to claim 7, wherein the third directional movement unit comprises a third motor, the third motor is fixedly disposed on the sample stage, a motor shaft of the third motor is connected to the connecting bracket, the connecting bracket is fixedly disposed on the second bearing stage, the second bearing stage is provided with a third slide rail, the sample stage is fixedly disposed with a third slide block, and the third slide block is slidably disposed on the third slide rail.
9. The electro-mechanical integrated sample loading device according to claim 8, wherein the first slide rail, the second slide rail and the third slide rail extend in directions perpendicular to each other.
10. Capillary electrophoresis apparatus, characterized in that it comprises an electromechanical integrated loading device according to any one of claims 1 to 9.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202021333141.2U CN212586294U (en) | 2020-07-08 | 2020-07-08 | Electromechanical integrated sample loading device and capillary electrophoresis apparatus |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202021333141.2U CN212586294U (en) | 2020-07-08 | 2020-07-08 | Electromechanical integrated sample loading device and capillary electrophoresis apparatus |
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| Publication Number | Publication Date |
|---|---|
| CN212586294U true CN212586294U (en) | 2021-02-23 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202021333141.2U Active CN212586294U (en) | 2020-07-08 | 2020-07-08 | Electromechanical integrated sample loading device and capillary electrophoresis apparatus |
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| CN (1) | CN212586294U (en) |
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- 2020-07-08 CN CN202021333141.2U patent/CN212586294U/en active Active
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