CN212369293U - Closed preparation device for antitumor drugs - Google Patents
Closed preparation device for antitumor drugs Download PDFInfo
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- CN212369293U CN212369293U CN202020661224.8U CN202020661224U CN212369293U CN 212369293 U CN212369293 U CN 212369293U CN 202020661224 U CN202020661224 U CN 202020661224U CN 212369293 U CN212369293 U CN 212369293U
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- JGSARLDLIJGVTE-MBNYWOFBSA-N Penicillin G Chemical compound N([C@H]1[C@H]2SC([C@@H](N2C1=O)C(O)=O)(C)C)C(=O)CC1=CC=CC=C1 JGSARLDLIJGVTE-MBNYWOFBSA-N 0.000 claims description 109
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Abstract
The utility model relates to the field of medical equipment, and discloses a closed preparation device for antitumor drugs, which comprises a cylinder body and a sleeve cap, wherein the inner wall of the cylinder body is provided with a flange, and the flange is made of elastic materials; a connecting pipe is fixed in the middle of the top of the sleeve cap, an injection needle pipe is coaxially arranged at the end of the connecting pipe close to the sleeve cap, and the needle tip of the injection needle pipe penetrates through the top cover of the sleeve cap and extends to the middle of the barrel; the end of the connecting pipe far away from the sleeve cap is provided with a pintle, and the injection needle tube and the pintle are communicated with the inner cavity of the connecting pipe. The utility model discloses an in inserting the xiLin bottle in the barrel and making the inboard injection needle tubing of cover cap pierce xiLin bottle, utilize the flange in the barrel to block xiLin bottle neck, inject menstruum liquid into xiLin bottle through injection needle tubing, then handheld barrel shakes the medicament in the xiLin bottle evenly, and the in-process can prevent that the liquid in the xiLin bottle from splashing to the air, prevents the medicine to the damage of medical staff mucous membrane or skin, has also avoided the emergence that the needle prick hindered.
Description
Technical Field
The utility model relates to the field of medical equipment, concretely relates to device is prepared to closed for anti-tumor drug.
Background
The penicillin bottle is a small glass container for containing powder or liquid medicaments, and the penicillin bottle structurally comprises a bottle body, a bottle head and a neck part, wherein the neck part is located between the bottle body and the bottle head, the capacity of the neck part is generally 1-20 ml, the penicillin bottle is generally used for injecting liquid medicine or medicinal powder, a bottle cap of the bottle head is generally made of rubber to form a rubber plug, and a layer of metal aluminum foil is further sleeved outside the rubber plug for sealing.
At present, when an antitumor drug in a penicillin bottle is prepared by adopting a traditional medicine preparation method, a syringe is generally used for sucking a solvent from an infusion bag or an infusion bottle, then a needle head of the syringe is inserted into the penicillin bottle to inject a liquid medicine into the penicillin bottle, the penicillin bottle is manually held to shake the liquid medicine in the penicillin bottle left and right, then the needle head is inserted into the penicillin bottle, the penicillin bottle is placed upside down, and the liquid medicine in the penicillin bottle is sucked out; and injecting the liquid medicine in the syringe into the infusion bag after suction, and pulling out the syringe to finally finish transferring and dispensing the liquid medicine or the medicinal powder in the penicillin bottle. According to the dispensing method, the manual injection and suction of the liquid medicine or the medicinal powder in the penicillin bottle are realized by using the handheld syringe, then the syringe is inserted into the infusion bag, and the liquid medicine is injected into the infusion bag, so that the operation steps are complicated, the time consumption is low, the efficiency is low, and the risk of needle stick injury and the risk of exposure of medical staff due to the fact that medicine molecules are dispersed in the air exist in the mode that the handheld syringe sucks the penicillin bottle or injects the liquid into the infusion bag. According to the records of related documents, particularly, chemotherapy drugs are harmful to various aspects of skin mucosa, bone marrow cells, reproductive systems and the like of normal human bodies, and the cost of the biological dispensing cabinet is extremely high, so that the popularization rate is low. In conclusion, the exposure of antineoplastic drug molecules to medical personnel has been immeasurable for a long time.
According to the global oncology report of 2014, the health care workers are at risk of exposure to hazardous drugs in the course of treating patients. It is expected that by 2015, there will be 1069 million healthcare workers threatened by the exposure of dangerous drugs in china. In 2016, the United states Pharmacopeia congress specified the handling of hazardous drugs and formally incorporated into the occupational safety program in 2018. The united states required all dispensing systems beginning in 2018 to try to use closed-system drug transfer devices (CSTD) as conditions warrant. Currently, CSTD is commonly used abroad: PhaSeal (Biansi)TM)，Chemoclave, Chemoprotect, Halo systems, etc., which have proven helpful in reducing contamination by antineoplastic drugs, among others, BD PhaSeal (Biansi)TM) The system is widely researched, but the system is high in price and complicated to operate. And the method is proposed according to the Chinese society of physicians, interventional physicians, published in 2019 "clinical practice guidelines for treating embolism by artery chemotherapy for liver cell treatment through artery therapy": hepatocellular carcinoma (HCC) is a malignant tumor originating from hepatocytes, and 80% of patients with HCC in china develop after infection with Hepatitis B Virus (HBV). HCC is usually a blood supply rich tumor, on one hand, tumor blood supply is blocked by arterial perfusion chemoembolization (TACE) treatment, and meanwhile, high-concentration chemotherapeutic drugs are accumulated in local tumor, so that tumor cells are killed to the maximum extent, and the method is known as one of common HCC non-operative treatment methods. Therefore, the demand of providing the economical sealed preparation device for the disposable anti-tumor medicament with the characteristics of China is urgent.
SUMMERY OF THE UTILITY MODEL
Based on above problem, the utility model provides a device is prepared to closed for anti-tumor drug, through inserting the xiLin bottle in the barrel and make the inboard injection needle tube of cover cap pierce xiLin bottle, utilize the flange in the barrel to block xiLin bottle neck, inject menstruum liquid into xiLin bottle through injection needle tube, then handheld barrel shakes the medicament in the xiLin bottle evenly, the in-process can prevent that the liquid in the xiLin bottle from splashing to the air, prevent the damage of medicine to medical staff mucous membrane or skin, the emergence of acupunture wound has also been avoided.
In order to solve the technical problem, the utility model discloses the technical scheme who adopts is:
a closed preparation device for antitumor drugs comprises a cylinder body with two open ends and an inner diameter larger than the outer diameter of a penicillin bottle, wherein one end of the cylinder body is provided with a sleeve cap capable of sealing the end of the cylinder body; one end of the sleeve cap is open, the other end of the sleeve cap is provided with a top cover, and a connecting pipe is fixed in the middle of the top of the sleeve cap; an injection needle tube is coaxially arranged at the end of the connecting tube close to the sleeve cap, the central axis of the injection needle tube and the central axis of the cylinder are positioned on the same straight line, and the needle tip of the injection needle tube penetrates through the top cover of the sleeve cap and extends to the middle position of the cylinder; the end of the connecting tube far away from the sleeve cap is provided with a pintle which can be sleeved with the injector nipple, and the injection needle tube and the pintle are communicated with the inner cavity of the connecting tube.
Furthermore, a necking section is arranged at the position, close to the top cover, of the inner wall of the sleeve cap, and an internal thread is arranged at the position, close to the opening, of the inner wall of the sleeve cap; the barrel outer wall position that the cover cap corresponds is provided with the screw thread with internal thread assorted, and the barrel end position that the cover cap corresponds is provided with a plurality of breach grooves along the barrel axial, and the length in breach groove is greater than the flange to the barrel end length that has the cover cap, and the breach groove is evenly cut apart into a plurality of bayonet socket pieces that have the flange with the barrel end.
Furthermore, the middle part of the connecting pipe is connected with a pipe joint through a three-way valve, and a control knob of the three-way valve is provided with a pointer for indicating the communication direction.
Further, the outer wall of the nipple of the injector is connected with the inner wall of the pintle through threads.
Furthermore, the sleeve cap and the cylinder body are both made of transparent materials.
Furthermore, the side wall of the injection needle tube is provided with a through hole penetrating through the tube wall of the injection needle tube, the through hole is positioned on the injection needle tube at a position close to the needle point, and the distance between the through hole and the needle point is more than or equal to the thickness of the bottle cap of the penicillin bottle.
Furthermore, a one-way air valve for medium to flow from the inner cavity of the injection needle tube to the needle point direction is arranged in the inner cavity of the injection needle tube, and the one-way air valve is positioned between the through hole and the needle point.
Furthermore, check valve is the duckbill valve, and the duckbill valve is made by elastic material including the inner tube that can be fixed in syringe needle inner chamber, the diameter of inner tube equals injection needle's internal diameter, and the port edge that the inner tube is close to the needle point is the closed V type structure of contact, and the point portion of V type structure is towards injection needle's needle point direction.
Compared with the prior art, the beneficial effects of the utility model are that:
1. the utility model discloses an in inserting the xiLin bottle in the barrel and making the inboard injection needle tubing of cover cap pierce xiLin bottle, utilize the flange in the barrel to block xiLin bottle neck, inject menstruum liquid into xiLin bottle through injection needle tubing, then handheld barrel shakes the medicament in the xiLin bottle evenly, and the in-process can prevent that the liquid in the xiLin bottle from splashing to the air, prevents the medicine to the damage of medical staff mucous membrane or skin, has also avoided the emergence that the needle prick hindered.
2. Utilize the sleeve cap to screw the bayonet socket piece of barrel, realize fixing xiLin bottle, the xiLin bottle is thrown away from the barrel when further preventing shaking even medicine.
3. The three-way valve and the catheter joint are additionally arranged on the connecting pipe, so that the three-way valve is controlled to realize the connection and disconnection of pipelines in the processes of solvent liquid injection, medicine suction and medicine transfer, the medicines in the whole process are in a closed environment, meanwhile, unnecessary plugging and unplugging pipelines are also reduced, and the medicines are further prevented from splashing or dripping.
4. The through hole is formed in the upper tube wall of the injection needle tube, so that firstly, the air pressure in the penicillin bottle can be balanced through the through hole in the puncturing process of the injection needle tube, and the problem of larger suction resistance caused by negative pressure existing in the penicillin bottle in the subsequent medicine suction process is solved; secondly, in the process of sucking the medicines by inverting the penicillin bottle, the through holes are positioned at the positions close to the inner wall of the bottle cap of the penicillin bottle, so that the medicines can be completely sucked, and the dosage of the medicines is ensured.
5. The one-way air valve is arranged between the needle point of the injection needle tube and the through hole, so that when the liquid level of the medicine in the penicillin bottle is lower than the needle point, the air in the penicillin bottle cannot be pumped out along with the medicine, and the problems that the medical staff needs to repeatedly exhaust the air and aerosol pollution is caused are solved.
Drawings
FIG. 1 is a schematic perspective view of a dispensing device for chemotherapeutic drugs in examples 1 and 2;
FIG. 2 is a schematic diagram showing the position of the injection needle tube relative to the vial in examples 1 and 2 when the air pressure is balanced by the through holes on the injection needle tube;
FIG. 3 is a schematic diagram showing the position of the injection needle tube relative to the vial when the vial is inverted to suck the drug through the through hole in examples 1 and 2;
FIG. 4 is a schematic view showing the positional relationship between the through hole and the check valve in the injection needle of examples 1 and 2;
FIG. 5 is a schematic structural diagram of a duckbill valve in the air flow in the examples 1 and 2, wherein the tip of the V-shaped structure contacts with a closing part and enters into a penicillin bottle;
wherein: 1. penicillin bottles; 2. a barrel; 3. sleeving a cap; 4. a flange; 5. a connecting pipe; 6. injecting a needle tube; 7. a pintle; 8. a necking section; 9. a bayonet piece; 10. a three-way valve; 11. a catheter adapter; 12. a through hole; 13. a duckbill valve; 14. a syringe.
Detailed Description
To make the objects, technical solutions and advantages of the present invention more apparent, the present invention is further described in detail below with reference to the following examples and drawings, and the exemplary embodiments and descriptions thereof of the present invention are only used for explaining the present invention, and are not intended as limitations of the present invention.
Example 1:
referring to fig. 1-3, a closed preparation device for antitumor drugs comprises a cylinder 2 with two open ends and an inner diameter larger than the outer diameter of a penicillin bottle 1, wherein one end of the cylinder 2 is provided with a sleeve cap 3 capable of sealing the end of the cylinder 2, the inner wall of the cylinder 2 is provided with a flange 4 capable of clamping the neck of the penicillin bottle 1, the flange 4 is positioned close to the end of the cylinder 2 with the sleeve cap 3, and the flange 4 is made of an elastic material; one end of the sleeve cap 3 is open, the other end is provided with a top cover, and the middle of the top of the sleeve cap 3 is fixed with a connecting pipe 5; an injection needle tube 6 is coaxially arranged at the end of the connecting tube 5 close to the sleeve cap 3, the central axis of the injection needle tube 6 and the central axis of the barrel 2 are positioned on the same straight line, and the needle tip of the injection needle tube 6 penetrates through the top cover of the sleeve cap 3 and extends to the middle position of the barrel 2; the end of the connecting pipe 5 far away from the sleeve cap 3 is provided with a pintle 7 which can be sleeved with the nipple of an injector 14, and the injection needle tube 6 and the pintle 7 are communicated with the inner cavity of the connecting pipe 5.
In the embodiment, when a drug needs to be dispensed from the penicillin bottle 1, a solvent liquid needed for dispensing the drug is extracted by using the syringe 14 in advance, then the cap of the penicillin bottle 1 is adjusted to face the same direction as the cap 3 of the cylinder 2, one end of the penicillin bottle 1 with the cap is inserted into the cylinder 2 from the open end of the cylinder 2 without the cap 3, the penicillin bottle 1 is forcibly pushed to enable the flange 4 in the cylinder 2 to clamp the neck of the penicillin bottle 1, and in the process of pushing the penicillin bottle 1, the injection needle tube 6 on the inner side of the cap 3 is gradually inserted into the inner cavity of the penicillin bottle 1. Then inserting the nipple of the injector 14 with the solvent liquid extracted into the pintle 7, and pushing the piston push rod of the injector 14 to make the solvent liquid in the injector 14 enter the penicillin bottle 1 through the inner cavity of the connecting pipe 5 and the injection needle tube 6 in sequence; then the injector 14, the cap 3 and the cylinder 2 are held by hands and shaken up to fully mix and dissolve the medicines in the penicillin bottle 1 in the cylinder 2, and then the piston push rod of the injector 14 is pulled to pump the mixed medicines in the penicillin bottle 1 into the injector 14, so as to realize the mixing configuration of the medicines in the penicillin bottle 1. In the process of shaking up the medicine preparation, the medicine liquid may leak from the gap between the injection needle tube 6 and the bottle cap of the penicillin bottle 1 when the solvent liquid is injected or shaken up, but the penicillin bottle 1 in the embodiment is positioned in the cylinder body 2 in the whole process of the medicine preparation (particularly in the process of shaking up) and is sealed by the cap sleeve 3, so that the leaked medicine liquid cannot splash to the skin of medical staff or be dispersed in the air, and particularly, the chemotherapeutic medicine or some medicines which have damage to the skin can play a good protection role. Meanwhile, the flange 4 in the cylinder body 2 is clamped at the neck of the penicillin bottle 1, so that the penicillin bottle 1 is not easy to separate from the cylinder body 2 and is thrown out, and the medicine preparation process is ensured to be carried out smoothly.
A necking section 8 is arranged at the position, close to the top cover, of the inner wall of the sleeve cap 3, and an internal thread is arranged at the position, close to the opening, of the inner wall of the sleeve cap 3; 2 outer wall positions of barrel that the cover cap 3 corresponds are provided with internal thread assorted screw thread, and 2 end positions of barrel that the cover cap 3 corresponds are provided with a plurality of breach grooves along 2 axial of barrel, and the length in breach groove is greater than flange 4 to 2 end lengths of barrel that have cover cap 3, and the breach groove is evenly cut apart into a plurality of bayonet socket pieces 9 that have flange 4 with 2 ends of barrel. In this embodiment, the cap 3 is connected to the barrel 2 through threads, so that the cap 3 and the barrel 2 are prevented from being separated from each other to throw the barrel 2 away during the shaking process of the medicine. In the process of screwing the sleeve cap 3 and the barrel 2 through the threads, after the end of the barrel 2 with the notch groove is contacted with the necking section 8 in the sleeve cap 3, the necking section 8 can gradually generate thrust action on each bayonet piece 9, so that each bayonet piece 9 is gradually drawn close to the central axis of the barrel 2, at the moment, the inner wall of the flange 4 or the bayonet piece 9 can generate holding force on the neck of the penicillin bottle 1 or the side wall of the body of the penicillin bottle 1, the penicillin bottle 1 is firmly clamped in the barrel 2, and the penicillin bottle 1 is further prevented from being thrown out in the process of shaking up the medicines. In addition, the outer wall of the nipple of the injector 14 is in threaded connection with the inner wall of the pintle 7, so that the pintle 7 can not be separated from the injector 14 due to pressure change in the shaking-up process.
The middle part of the connecting pipe 5 is connected with a conduit joint 11 through a three-way valve 10, the conduit joint 11 in the embodiment is used for transferring the prepared medicine in the injector 14 to an infusion bag, an infusion bottle or other medicine transfer conveying equipment, or an injection needle is arranged at the front end of the conduit joint 11 according to requirements to directly inject the medicine to a patient, the medicine is in a sealed environment in the whole operation process, the insertion and extraction of the injector 14 or a conveying pipeline in the middle process are reduced, and the medicine is further prevented from dropping or splashing in the medicine transfer process.
The sequence of operation of the three-way valve 10 is: after the penicillin bottle 1 is pushed into the cylinder body 2, the injection needle tube 6 is inserted into the penicillin bottle 1, a control knob of the three-way valve 10 is adjusted to enable the pintle 7 (the injector 14) -the connecting tube 5-the injection needle tube 6 to be in a passage, the conduit joint 11 and the connecting tube 5 to be in an open circuit state, then the solvent liquid in the injector 14 is injected into the penicillin bottle 1, and the mixture is shaken up to enable the medicament in the penicillin bottle 1 to be completely dissolved; keeping the passage of the pintle 7, the connecting pipe 5 and the injection needle tube 6, keeping the pipe joint 11 and the connecting pipe 5 in an open circuit state, and extracting the medicine in the penicillin bottle 1 into the injector 14 by using the injector 14; then the control knob of the three-way valve 10 is adjusted to make the pintle 7 (injector 14) -the connecting pipe 5-the conduit joint 11 in a passage, and the injection needle pipe 6 and the connecting pipe 5 in a circuit breaking state, and then the medicine in the injector 14 is pushed out to the conduit joint 11 and is guided into corresponding equipment by the conduit joint 11 or is directly injected into a patient. In this embodiment, a pointer for indicating the communication direction is provided on the control knob of the three-way valve 10, so that medical staff can intuitively and quickly determine the on-off path of the three-way valve 10, and the operation of the medical staff is facilitated.
Referring to fig. 1-4, the side wall of the injection needle tube 6 is provided with a through hole 12 penetrating through the tube wall of the injection needle tube 6, the through hole 12 is positioned on the injection needle tube 6 near the needle point, and the distance between the through hole 12 and the needle point is larger than or equal to the thickness of the bottle cap of the vial 1. Because the penicillin bottle 1 is in a negative pressure state under most conditions, especially when the medicament in the penicillin bottle 1 is powder, if the amount of the solvent liquid injected into the injection needle tube 6 is small, the penicillin bottle 1 is still in the negative pressure state, and medical staff is difficult to extract the medicament in the penicillin bottle 1 in the subsequent medicament extraction process by adopting the injector 14, so that time and labor are wasted. In the embodiment, when the needle tip of the injection needle tube 6 pierces the bottle cap of the penicillin bottle 1 and gradually extends into the inner cavity of the penicillin bottle 1, and the through hole 12 is positioned outside the bottle cap of the penicillin bottle 1, the needle tip part of the injection needle tube 6 and the through hole 12 on the tube wall communicate the air pressure inside the penicillin bottle 1 with the air pressure outside the penicillin bottle 1, so that the air pressure inside the penicillin bottle 1 is balanced with the air pressure outside the penicillin bottle 1; then, the injection needle tube 6 is continuously punctured, the through hole 12 is positioned in the penicillin bottle 1, and then the solvent liquid is pushed in to carry out the drug configuration. In the subsequent medicine extraction process, the suction resistance is small when the medicine is extracted, and the problem of difficult medicine suction can not occur.
In addition, when the injection needle in the prior art is used for extracting the medicine in the penicillin bottle 1, in order to ensure that the medicine in the penicillin bottle 1 is completely extracted, generally, the syringe 14 is turned upwards, the penicillin bottle 1 is turned upside down, then the needle point of the injection needle is gradually pulled outwards, the needle point is close to the inner side of the bottle cap of the penicillin bottle 1, and then the medicine in the penicillin bottle 1 is sucked; when the medicine in the penicillin bottle 1 is sucked to be close to the bottle cap of the penicillin bottle 1, in order to ensure that the liquid level in the penicillin bottle 1 is over the needle point, the injection needle head needs to be pulled out while sucking. The operation of the process is complicated, the injection needle can be directly pulled out by carelessness, and the risk of stabbing medical staff exists; and the medicine in the penicillin bottle 1 is not completely drawn out, and the injection needle needs to be repeatedly punctured into the penicillin bottle 1. In the embodiment, the through hole 12 is formed in the tube wall of the injection needle tube 6, the sleeve cap 3 and the barrel body 2 are both made of transparent materials, when the penicillin bottle 1 is pushed into the barrel body 2, the injection needle tube 6 penetrates into the penicillin bottle 1, medical staff can make the through hole 12 be just positioned in the penicillin bottle 1 at a position close to the bottle cap of the penicillin bottle 1 by observing and adjusting the position of the through hole 12, and then the solvent liquid is injected. When the medicine in the penicillin bottle 1 needs to be pumped out, the sleeve cap 3 covered on the barrel body 2 faces downwards, the bottle cap of the penicillin bottle 1 faces downwards at the moment, the medicine in the penicillin bottle 1 can be directly pumped out, the medicine in the penicillin bottle 1 can be completely pumped out through the through hole 12 at the moment, and even if the position of the through hole 12 needs to be adjusted in the puncturing process, the problem that the whole injection needle tube 6 is pulled out is not easy to occur.
The inner cavity of the injection needle tube 6 is provided with a one-way air valve which can allow the medium to flow from the inner cavity of the injection needle tube 6 to the needle point direction, and the one-way air valve is positioned between the through hole 12 and the needle point. When the medicine in the penicillin bottle 1 is extracted through the through hole 12, when the liquid level of the medicine in the penicillin bottle 1 is lower than the needle point, the gas in the penicillin bottle 1 can be easily extracted through the needle point, so that the medicine is mixed with the gas, and the injector 14 needs to be repeatedly adjusted to remove the gas in the subsequent operation process; the arrangement of the one-way air valve can ensure that the air entering from the through hole 12 enters the needle tip part through the one-way air valve and then is discharged into the penicillin bottle 1 in the process that the injection needle tube 6 is inserted into the penicillin bottle 1 so as to balance the air pressure in the penicillin bottle 1 and reduce the suction resistance when the subsequent medicine is extracted; and when the liquid level of the medicine is lower than the needle point in the suction process, the gas in the penicillin bottle 1 can not enter the injection needle tube 6 through the needle point part, so that the medical staff does not need to repeatedly adjust the injector 14 to remove the gas, and the time and the labor are saved.
Referring to fig. 1-5, the one-way air valve in this embodiment is a duckbill valve 13, the duckbill valve 13 includes an inner tube capable of being fixed in the inner cavity of the injection needle tube 6, the inner tube is made of an elastic material, the diameter of the inner tube is equal to the inner diameter of the injection needle tube 6, the edge of the port of the inner tube close to the needle point is in a contact closed V-shaped structure, and the tip of the V-shaped structure faces the needle point direction of the injection needle tube 6. When injection needle tube 6 pierces xiLin bottle 1 and through-hole 12 is located xiLin bottle 1 outside, external gas gets into injection needle tube 6 through-hole 12, then gets into duckbill valve 13's inner tube, struts V type structure point contact closed position, and gas then gets into needle point one side by V type structure point, gets into xiLin bottle 1 at last in, realizes the interior and the outer atmospheric pressure balance of bottle. In the process of sucking the inverted medicine in the penicillin bottle 1, the outside air or liquid generates a downward pushing force at the tip part of the V-shaped structure, and the contact and closing part of the V-shaped structure is contacted more tightly, so that the liquid or the gas cannot enter the injection needle tube 6 through the needle point of the injection needle tube 6, and particularly, when the liquid level in the penicillin bottle 1 is lower than the needle tip part, the gas in the penicillin bottle 1 cannot be sucked into the injector 14.
It should be noted that the materials contacting with the drug or solvent liquid, such as the cap 3, the injection needle tube 6, the three-way valve 10, the pintle 7, the catheter adapter 11, etc., in this embodiment are all disposable, so as to prevent cross contamination; the barrel 2 with the flange 4 and the bayonet piece 9 can be in no contact with the medicine in the whole operation process, so that the barrel 2 can be repeatedly used under the condition of not being polluted by the medicine, resources are saved, consumption is reduced, and cost is saved.
In addition, the cap 3 and the barrel 2 may be made of glass or other transparent moldable and non-polluting materials, and the injection needle tube 6 may be made of plastic or metal. The cap 3 and the barrel 2 in this embodiment are both made of transparent polycarbonate, and the injection needle tube 6 is made of plastic, so that the cost is low and the processing and molding are easy.
Example 2
Referring to fig. 1-5, a method of using a closed dispensing device for antineoplastic drugs is:
s1, inserting the end of the penicillin bottle 1 with the bottle cap into the cylinder 2 from the open end of the cylinder 2 without the sleeve cap 3, pushing the penicillin bottle 1 to clamp the neck of the penicillin bottle 1 by the inner flange 4 of the cylinder 2, gradually inserting the tip of the injection needle tube 6 on the inner side of the sleeve cap 3 into the inner cavity of the penicillin bottle 1, keeping the through hole 12 outside the penicillin bottle 1, and balancing the air pressure in the penicillin bottle 1;
s2, gradually puncturing the injection needle tube 6 into the penicillin bottle 1 until the through hole 12 is positioned in the inner cavity of the penicillin bottle 1 and close to the inner wall of the bottle cap, inserting the nipple of the injector 14 which extracts the solvent liquid into the pintle 7, and pushing the piston push rod of the injector 14 to enable the solvent liquid in the injector 14 to sequentially enter the penicillin bottle 1 through the inner cavity of the connecting tube and the injection needle tube 6;
s3, holding the syringe 14 by hand, sleeving the cap 3 and the barrel 2, shaking up the medicines in the penicillin bottle 1 to fully mix and dissolve the medicines in the penicillin bottle 1 in the barrel 2, inverting the barrel 2 to enable the bottle cap of the penicillin bottle 1 to face downwards, pulling the piston push rod of the syringe 14, and pumping the mixed medicines in the penicillin bottle 1 into the syringe 14. On the basis of preventing the medicine from splashing in the medicine mixing process, the through hole 12 is formed in the injection needle tube 6, so that the balance of air pressure in the penicillin bottle 1 is realized, and the problem of large air pressure resistance in the solvent injection process is avoided.
The middle part of the connecting pipe is connected with a conduit joint 11 through a three-way valve 10, after the mixed medicine in the penicillin bottle 1 is pumped to an injector 14, the three-way valve 10 is adjusted to enable the injector 14, the connecting pipe and the conduit joint 11 to be in a passage state, and then the prepared medicine in the injector 14 is transferred to an infusion bag, an infusion bottle or other medicine transfer conveying equipment through the conduit joint 11 by pushing a piston push rod of the injector 14, so that the medicine in the whole preparation process of the chemotherapy medicine is in a sealed environment.
Other parts in this embodiment are the same as embodiment 1, and are not described again here.
The embodiment of the present invention is the above. The specific parameters in the above embodiments and examples are only for the purpose of clearly showing the verification process of the present invention, and are not used to limit the protection scope of the present invention, which is still subject to the claims, and all the equivalent structural changes made by using the contents of the specification and drawings of the present invention should be included in the protection scope of the present invention.
Claims (8)
1. A closed dispensing device for antineoplastic drugs, characterized in that: the penicillin bottle opening device comprises a barrel body (2) with two open ends and an inner diameter larger than the outer diameter of a penicillin bottle (1), wherein a sleeve cap (3) capable of sealing the end of the barrel body (2) in a covering mode is arranged at one end of the barrel body (2), a flange (4) capable of clamping the neck of the penicillin bottle (1) is arranged on the inner wall of the barrel body (2), the flange (4) is located close to the end of the barrel body (2) with the sleeve cap (3), and the flange (4) is made of elastic materials; one end of the sleeve cap (3) is open, the other end of the sleeve cap is provided with a top cover, and a connecting pipe (5) is fixed in the middle of the top of the sleeve cap (3); an injection needle tube (6) is coaxially arranged at the end of the connecting tube (5) close to the sleeve cap (3), the central axis of the injection needle tube (6) and the central axis of the barrel (2) are positioned on the same straight line, and the needle tip of the injection needle tube (6) penetrates through the top cover of the sleeve cap (3) and extends to the middle position of the barrel (2); keep away from connecting pipe (5) end of cover cap (3) is provided with pintle (7) that can cup joint with syringe (14) nipple, injection needle tubing (6) with pintle (7) all with the inner chamber intercommunication of connecting pipe (5).
2. The hermetic dispensing device for antitumor drugs as in claim 1, characterized in that: a necking section (8) is arranged at the position, close to the top cover, of the inner wall of the sleeve cap (3), and an internal thread is arranged at the position, close to the opening, of the inner wall of the sleeve cap (3); barrel (2) outer wall position that cover cap (3) correspond is provided with the screw thread with internal thread assorted, barrel (2) end position that cover cap (3) correspond is provided with a plurality of breach grooves along barrel (2) axial, the length in breach groove is greater than flange (4) to the barrel (2) end length that has cover cap (3), the breach groove will barrel (2) end evenly cut apart into a plurality of bayonet socket pieces (9) that have flange (4).
3. The hermetic dispensing device for antitumor drugs as in claim 1, characterized in that: the middle part of the connecting pipe (5) is connected with a conduit joint (11) through a three-way valve (10), and a control knob of the three-way valve (10) is provided with a pointer for indicating the communication direction.
4. The hermetic dispensing device for antitumor drugs as in claim 1, characterized in that: the outer wall of the nipple of the injector (14) is connected with the inner wall of the pintle (7) through screw threads.
5. The hermetic dispensing device for antitumor drugs according to any one of claims 1 to 4, characterized in that: the side wall of the injection needle tube (6) is provided with a through hole (12) penetrating through the tube wall of the injection needle tube (6), the through hole (12) is located on the injection needle tube (6) and close to the needle point, and the distance between the through hole (12) and the needle point is larger than or equal to the thickness of a bottle cap of the penicillin bottle (1).
6. A closed dispensing device for antineoplastic drugs according to claim 5, characterized in that: the sleeve cap (3) and the barrel body (2) are both made of transparent materials.
7. A closed dispensing device for antineoplastic drugs according to claim 6, characterized in that: and a one-way air valve which can allow a medium to flow from the inner cavity of the injection needle tube (6) to the needle point direction is arranged in the inner cavity of the injection needle tube (6), and the one-way air valve is positioned between the through hole (12) and the needle point.
8. A closed dispensing device for antineoplastic drugs according to claim 7, characterized in that: one-way air valve is duckbilled valve (13), duckbilled valve (13) are including being fixed in the inner tube of injection needle pipe (6) inner chamber, the inner tube is made by elastic material, the diameter of inner tube equals the internal diameter of injection needle pipe (6), the port edge that the inner tube is close to the needle point is the closed V type structure of contact, the point portion of V type structure is towards the needle point direction of injection needle pipe (6).
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| CN202020661224.8U CN212369293U (en) | 2020-04-27 | 2020-04-27 | Closed preparation device for antitumor drugs |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114504497A (en) * | 2022-02-22 | 2022-05-17 | 陕西理工大学 | Anti-bacterial and anti-bending syringe needle cover |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114504497A (en) * | 2022-02-22 | 2022-05-17 | 陕西理工大学 | Anti-bacterial and anti-bending syringe needle cover |
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