CN212135058U

CN212135058U - High-flux automatic slice scanning system

Info

Publication number: CN212135058U
Application number: CN202021192232.9U
Authority: CN
Inventors: 胡亦宁; 吴亮明; 董蜀湘; 义兴宇
Original assignee: Heidstar Technology Xiamen Co ltd
Current assignee: Heidstar Technology Xiamen Co ltd
Priority date: 2020-06-24
Filing date: 2020-06-24
Publication date: 2020-12-11
Anticipated expiration: 2030-06-24

Abstract

The utility model provides an automatic section scanning system of high flux, include base, microscope system, objective table, advance the piece device and move back the piece device. The microscope system is arranged on the base and comprises a microscope, a lifting device and an electric objective lens switching device. The stage is located below the microscope system. The objective table comprises an xy motion platform and a slicing disc clamping device. The slide feeding device is arranged at the slide feeding side of the objective table and comprises a slide feeding library, a slide tray arrangement guide structure, a falling guide mechanism and a slide tray feeding mechanism. The piece withdrawing device is arranged on the piece withdrawing side of the objective table and comprises a piece withdrawing library, a slicing disc arranging structure, a slicing disc lifting device and a slicing disc hooking device. The utility model discloses an advance the piece storehouse and can hold a large amount of slice dishes, improved the efficiency of single scanning, reduced artificial intervention to realize sliced continuous scanning. The slice feeding process, the slice withdrawing process and the scanning motion are independently driven, so that the slice handover preparation time is reduced.

Description

High-flux automatic slice scanning system

Technical Field

The utility model relates to a microscope automatic scanning technical field particularly, relates to an automatic section scanning system of high flux.

Background

The section is a slice which is made by cutting a sample such as a tissue and the like by using a special cutter and adopting a corresponding preparation method, and can be used for observing and researching the sample such as the tissue and the like. Optical microscopy is an important tool for slice scanning. In the development of microscope technology, technologies such as microelectronics and information technology are applied to an optical microscope in a comprehensive manner, so that the optical microscope can complete imaging digital signal acquisition and digital processing. However, with the increasing number of slices to be scanned and the development of digital slicing technology, how to realize the automatic advance and retreat of high-throughput slices and reduce manual participation has become the development direction of pathological section optical microscope scanning systems.

An active tilting type automatic feeding and withdrawing scanning microscope is disclosed in the patent with the application number of 201620921591.0, and a scanning system of the microscope comprises a microscope, a scanning feeding mechanism, a feeding system and a collecting system; the scanning and feeding mechanism is used as a unique slice driving structure to complete the operation of feeding, withdrawing and reciprocating scanning in the feeding direction; the microscope is moved in a plane perpendicular to the scan feed direction to complete the in-focus scanning process. However, this apparatus has the following problems: 1. the automatic sheet feeding process is based on the dead weight of the sheet cutting frame to realize the automatic falling of the stacked sheet cutting frame, and the sudden change force of the falling process not only can impact the sheet cutting frame and fragile glass sheets, but also can influence the stability of sheet clamping. As the number of stacked slices increases, the likelihood of destroying the slices increases, thus limiting the total number of slices in a single stack placement; 2. the scanning feeding mechanism is used as the only driving source, so that the structure is simplified, but one-time complete scanning is completed, the film advancing and retreating process is completely independent of the scanning process, the time of the film advancing and retreating occupying the scanning process is difficult to reduce in the driving principle, and the whole scanning efficiency is reduced; 3. the device is not flexible enough. In the scanning process, the xy axis movement is too heavy, so that the scanning precision and the movement performance are greatly weakened, and the stable acquisition process of the microscopic image is extremely unfavorable.

The microscope advancing and retracting mechanisms disclosed in the patent application nos. 201620750044.0, 201620570801.6, 201620570549.9 and 201620916762.0 are similar to the microscope advancing and retracting mechanism disclosed in the patent application No. 201620921591.0, and all have the above disadvantages.

The patent with application number 201920772710.4 discloses a pathological section scanning image analysis system, which comprises a base, a slide loading mechanism and a slide shooting and scanning mirror; the base drives the motion of microscope YZ axle direction and the X axle removal separation of slide frame, places and takes away the slide frame through the manual work, and scanning process goes on automatically. The equipment is provided with the slide rack manually, and the placing position of the slide is limited, so that the slice scanning efficiency is lower and the stability is poorer.

SUMMERY OF THE UTILITY MODEL

The utility model provides an automatic section scanning system of high flux aims at improving current section scanning system efficiency not high, the capacity is limited and stability and compatible poor scheduling problem.

The utility model discloses a realize like this:

a high-flux automatic slice scanning system comprises a base, a microscope system, an object stage, a slice feeding device and a slice returning device;

the microscope system is arranged on the base and positioned in the middle of the base, the microscope system comprises a microscope, a lifting device and an electric objective lens switching device, the lifting device is used for driving the microscope and the electric objective lens switching device to move along the direction vertical to the objective table, and a plurality of objective lenses are arranged on the electric objective lens switching device;

the objective table is arranged on the base and is positioned below the microscope system, and the objective table comprises an xy motion platform and a slice tray clamping device arranged on the xy motion platform;

the slice feeding device is arranged on the base and positioned on the slice feeding side of the objective table, the slice feeding device comprises a slice feeding library, a slice tray arrangement guide structure, a falling guide mechanism and a slice tray feeding mechanism used for driving the slice tray to move along the direction close to the objective table, the falling guide mechanism is provided with the slice feeding library, the inner side of the falling guide mechanism is provided with the slice tray arrangement guide structure, and the slice tray feeding mechanism is arranged in the middle of the slice tray arrangement guide structure and positioned below the slice tray arrangement guide structure;

the piece withdrawing device is arranged on the base and is located the piece withdrawing side of the objective table, the piece withdrawing device comprises a piece withdrawing library, a piece tray arrangement structure, a piece tray lifting device and a piece tray hook pulling device, the piece tray arrangement structure is provided with one piece withdrawing library, the middle part of the piece tray arrangement structure is provided with one piece tray lifting device, the piece tray lifting device is driven by the piece tray hook pulling device, the piece tray hook pulling device is also used for connecting the piece tray and driving the piece tray to be close to the piece withdrawing device to move on one side.

Further, in the preferred embodiment of the present invention, the lifting device is disposed in the middle of the base, the front end of the lifting device is provided with a microscope, the objective interface of the microscope is fixed with an electric objective switching device, the objective is disposed on the electric objective converter and located above the objective table, and the electric objective switching device is electrically driven by the electric objective to switch the objective.

Further, in the preferred embodiment of the present invention, the holding device of the slice tray is provided with a guide slot adapted to the slice tray, and a plurality of elastic pressing pieces are symmetrically distributed on both sides of the guide slot.

Further, in the preferred embodiment of the present invention, a plurality of slicing grooves for placing slices are formed on the upper surface of the slicing tray, each slicing groove is at least provided with an elastic pressing sheet, the front end of the slicing tray is provided with a withdrawing hook groove, the lower surface of the rear end of the slicing tray is provided with a pushing sheet structure, the withdrawing hook groove is an open hook groove structure, the pushing sheet structure is an inclined triangular pushing sheet structure, and the withdrawing grooves adapted to the guide grooves are respectively formed on the two sides of the slicing tray.

Further, in the preferred embodiment of the present invention, the slicing tray feeding mechanism includes a pushing structure, and the pushing structure is used for abutting against the pushing structure and pushing the slicing tray to move.

Further, in the preferred embodiment of the present invention, the slicing tray hook pulling device is disposed below the middle portion of the slicing tray arrangement structure, and is located below the slicing tray lifting device, the slicing tray hook pulling device is further provided with a hook pulling structure matched with the sheet returning hook groove, the hook pulling structure is vertically arranged on the slicing tray lifting device, the slicing tray lifting device is provided with the cam follower mechanism, and the cam follower mechanism passes through the driving of the slicing tray hook pulling device and can be used for lifting the slicing tray.

Further, in the preferred embodiment of the present invention, the slicing plate placing guide structure comprises two symmetrically arranged two-step structures with small step slope angles.

Further, in the preferred embodiment of the present invention, the falling guide mechanism includes a plurality of falling guide arms, two of which are disposed on the inner side wall of the falling guide arm, a plurality of equidistant spring thimbles are further disposed on the inner side wall of the falling guide arm, and the spring thimbles are disposed above the second-level step structure.

Further, in the preferred embodiment of the present invention, the sheet feeding magazine comprises a first sheet feeding magazine baffle and a second sheet feeding magazine baffle parallel to each other, the first sheet feeding magazine baffle and the second sheet feeding magazine baffle are respectively and vertically arranged on the falling guiding mechanism, the first sheet feeding magazine baffle and the second sheet feeding magazine baffle are vertically arranged on the sheet tray mounting structure, the bottom of the first sheet feeding magazine baffle and the bottom of the first sheet feeding magazine baffle are respectively provided with an opening for the sheet feeding or the sheet feeding of the sheet tray, and the height of the opening is greater than the height of the sheet tray.

The utility model has the advantages that:

1. the utility model discloses install the section on the section dish of fixed specification. Advance the piece and move back the piece in-process, many sliced shifts, motion all carry out whole piece from top to bottom through the section dish, have not only avoided the emergence of card, make simultaneously the effort that receives in the piece in-process from top to bottom be used for the section dish, have protected breakable glass section. The falling guide device is further arranged in the sheet feeding warehouse, when the sheet feeding of the sheet tray is carried out by the falling guide mechanism, the pushing speed of the sheet tray is reduced under the action of the spring ejector pins, so that the sheet tray slowly breaks away from the sheet tray to arrange the guide structure, and the sheet tray positioned above the sheet tray slowly falls onto the sheet tray to arrange the guide structure, thereby avoiding the occurrence of the phenomenon that the sheet specimen is damaged under the action of constant external force and sudden external force.

2. The utility model discloses an advance the piece storehouse and can hold a large amount of film cutting discs, realize advancing the piece storehouse polydisc and go up the piece, not only improved the efficiency of single scanning, reduced artificial intervention, but also can be constantly to advancing the piece storehouse at the scanning in-process and add the film cutting disc to realize sliced continuous scanning.

3. The vertical motion of the microscope system and the horizontal motion of the xy motion platform are independent, so that the motion stability and the motion dynamic performance are improved, and high-precision scanning is realized. The slice disc can reciprocate on the objective table along the x-axis direction and the y-axis direction, and can support various focusing modes and multi-region and multi-layer scanning by matching with an electric objective lens converter, and meanwhile, the slice disc is compatible with standard or thickened slices.

4. The feeding process, the withdrawing process and the scanning motion are driven independently. The film feeding preparation and the film withdrawing preparation are respectively independent of the scanning process, the preparation time of the film transfer is reduced, the proportion of the film feeding and the film withdrawing in the overall scanning process can be reduced, and the working efficiency is improved.

Drawings

In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the drawings that are required to be used in the embodiments will be briefly described below, it should be understood that the following drawings only illustrate some embodiments of the present invention, and therefore should not be considered as limiting the scope, and for those skilled in the art, other related drawings can be obtained according to the drawings without inventive efforts.

Fig. 1 is a schematic structural diagram of a high throughput automated slice scanning system according to a first embodiment of the present invention at a first viewing angle;

fig. 2 is a schematic structural diagram of the high throughput automated slice scanning system according to the first embodiment of the present invention at a second viewing angle;

FIG. 3 is a schematic view of a partial structure of a sheet feeding device according to a first embodiment of the present invention;

fig. 4 is a schematic partial structure diagram of a sheet withdrawing device according to a first embodiment of the present invention;

fig. 5 is a schematic structural diagram of a slicing tray according to a first embodiment of the present invention at a first viewing angle;

fig. 6 is a schematic structural view of the slicing tray according to the first embodiment of the present invention at a second viewing angle;

fig. 7 is a flowchart illustrating a scanning method of the high throughput automated slice scanning system according to the first embodiment of the present invention.

Detailed Description

To make the objects, technical solutions and advantages of the embodiments of the present invention clearer, the drawings of the embodiments of the present invention are combined to clearly and completely describe the technical solutions of the embodiments of the present invention, and obviously, the described embodiments are some embodiments of the present invention, not all embodiments. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative work belong to the protection scope of the present invention. Thus, the following detailed description of the embodiments of the present invention, presented in the accompanying drawings, is not intended to limit the scope of the invention, as claimed, but is merely representative of selected embodiments of the invention. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative work belong to the protection scope of the present invention.

In the description of the present invention, it is to be understood that the terms "center", "longitudinal", "lateral", "length", "width", "thickness", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", "clockwise", "counterclockwise", and the like indicate orientations or positional relationships based on the orientations or positional relationships shown in the drawings, and are only for convenience of description and to simplify the description, but do not indicate or imply that the device or element referred to must have a particular orientation, be constructed and operated in a particular orientation, and therefore should not be construed as limiting the present invention.

Furthermore, the terms "first", "second" and "first" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance or implicitly indicating the number of technical features indicated. Thus, a feature defined as "first" or "second" may explicitly or implicitly include one or more of that feature. In the description of the present invention, "a plurality" means two or more unless specifically limited otherwise.

In the present invention, unless otherwise expressly stated or limited, the terms "mounted," "connected," and "fixed" are to be construed broadly and may, for example, be fixedly connected, detachably connected, or integrally formed; can be mechanically or electrically connected; either directly or indirectly through intervening media, either internally or in any other relationship. The specific meaning of the above terms in the present invention can be understood according to specific situations by those skilled in the art.

In the present disclosure, unless expressly stated or limited otherwise, the first feature "on" or "under" the second feature may comprise direct contact between the first and second features, or may comprise contact between the first and second features not directly. Also, the first feature being "on," "above" and "over" the second feature includes the first feature being directly on and obliquely above the second feature, or merely indicating that the first feature is at a higher level than the second feature. A first feature being "under," "below," and "beneath" a second feature includes the first feature being directly under and obliquely below the second feature, or simply meaning that the first feature is at a lesser elevation than the second feature.

Referring to fig. 1, 2, 3 and 4, a first embodiment of the present invention provides a high throughput automatic slice scanning system, which includes a base 1, a microscope system 2, an object stage 3, a slice feeding device 4 and a slice returning device 5.

The microscope system 2 is arranged on the base and is positioned in the middle of the base 1. The microscope system 2 includes a microscope 21, a lifting device 22, and a motorized objective lens switching device 23. The lifting device 22 is used to drive the microscope 21 and the electric objective lens switching device 23 to move in a direction perpendicular to the stage 3. The electromotive objective lens switching device 23 is provided with a plurality of objective lenses 24.

In this embodiment, the elevating device 22 is provided at the center of the base 1, and the microscope 21 is provided at the tip of the elevating device 22. An electric objective lens switching device 23 is fixedly arranged at the objective lens interface of the microscope 21. The objective lens 24 is provided on the motorized objective lens changer 23 and is positioned above the stage 3. The electric objective lens switching device 23 electrically drives switching of the objective lens 24.

The stage 3 is provided on the base 1 and located below the microscope system 2. The stage 3 includes an xy-motion stage 31 and a slice tray holding device 32 provided on the xy-motion stage 31.

Referring to fig. 1, 5 and 6, in the present embodiment, the slicing tray holding device 32 is provided with a guide slot 321 adapted to the slicing tray 6, and a plurality of elastic pressing pieces 322 are symmetrically distributed on two sides of the guide slot 321. The upper surface of the slicing disc 6 is provided with a plurality of slicing grooves 61 for placing slices, and each slicing groove 61 is provided with at least one elastic pressing sheet 62. The front end of the slicing disc 6 is provided with a piece withdrawing hook groove 63, and the lower surface of the rear end of the slicing disc is provided with a piece pushing structure 64. Preferably, the piece withdrawing hook groove 63 is an open hook groove structure, and the piece pushing structure 64 is an inclined triangular piece pushing structure. The two sides of the slicing disc 6 are respectively provided with an avoiding groove 65 matched with the guide groove 321.

Referring to fig. 1 and 3, the sheet feeder 4 is provided on the base 1 and positioned on the sheet feeding side of the stage 3. The sheet feeding device 4 includes a sheet feeding magazine 41, a tray placement guide 42, a drop guide mechanism 43, and a tray feeding mechanism 44 for driving the tray in a direction close to the stage. The falling guide mechanism 43 is provided with a sheet inlet storage 41, the inner side of the falling guide mechanism 43 is provided with a slicing tray arranging guide structure 42, and a slicing tray feeding mechanism 44 is arranged in the middle of and below the slicing tray arranging guide structure 42.

Referring to fig. 3, in the present embodiment, the slicing tray feeding mechanism 44 includes a pushing structure 441, and the pushing structure 441 abuts against the pushing structure 64 and pushes the lowest slicing tray to move.

Referring to fig. 3, in the present embodiment, the section tray seating guide 42 includes two symmetrically disposed two-step structures having a small step slope angle. The sliced plate 6 is pushed by the pushing structure 441 obliquely downward along the second step of the sliced plate seating guide structure 42 into the sliced plate holding device 32.

Referring to fig. 1, 3 and 6, the falling guide mechanism 43 includes falling guide arms 431 respectively provided at both sides of the cutter tray feeding mechanism 44, and a two-step structure is provided on inner sidewalls of the two falling guide arms 431, respectively. A plurality of spring thimbles 432 at equal intervals are further arranged on the inner side wall of the falling guide arm 431, and the spring thimbles 432 are arranged above the secondary step structure. When the slicing disc 6 enters the slicing disc, the falling guide mechanism 43 slows down the pushing speed of the slicing disc 6 through the action of the spring ejector pins 432, so that the slicing disc 6 is slowly separated from the slicing disc installation guide structure 42 in the inclined downward moving process, and a slicing disc positioned on the slicing disc can not follow and advance due to the friction action of the previous slicing disc because of being blocked by the pushing structure 441 in the falling process, and can only slowly fall onto the slicing disc installation guide structure 42, thereby avoiding the phenomenon that a slicing specimen is damaged due to the action of constant external force and sudden external force. After the slicing tray 6 is clamped in the slicing tray clamping device 32, the slicing tray feeding mechanism 44 retreats, and the pushing structure 441 slides over the pushing structure 64 of the slicing tray 6 to return to the initial position, thereby completing the feeding operation.

Referring to fig. 1 and 4, the sheet withdrawing device 5 is disposed on the base 1 and located on the sheet withdrawing side of the stage 3, and the sheet withdrawing device 5 includes a sheet withdrawing magazine 51, a sheet tray placing structure 52, a sheet tray lifting device 53, and a sheet tray hooking device 54. The slice tray arrangement structure 52 is provided with a slice withdrawing library 51, the middle part of the slice tray arrangement structure 52 is provided with a slice tray lifting device 53, and the slice tray lifting device 53 is driven by a slice tray hook-pulling device 54. The slicing disc hooking device 54 is also used for connecting with the slicing disc 6 and driving the slicing disc 6 to move along the side close to the disc withdrawing device 5.

Referring to fig. 1, 4 and 5, in the present embodiment, a tray hooking device 54 is provided below the middle portion of the tray arrangement structure 52 and below the tray lifting device 53. The slicing tray hooking device 54 is further provided with a hooking structure 541 matched with the slice withdrawing hook groove 63, and the hooking structure 541 is vertically arranged on the slicing tray lifting device 53 in a penetrating manner. When withdrawing the slice, the initial position of the hooking structure 541 is located at one side of the withdrawing device 5 close to the object stage 3, the xy moving platform 31 drives the withdrawing hook groove 63 of the slice tray 6 to complete connection with the hooking device 541, and the slice tray hooking device 54 moves towards one side far away from the object stage 3 to take out the slice tray 6 from the slice tray holding device 32 until completely separating from the slice tray holding device 32.

In this embodiment, the slicing tray lifting device 53 is provided with a cam follower mechanism, and the cam follower mechanism is driven by the slicing tray hooking device 54 and can be used for lifting the slicing tray 6. When the slide tray hooking means 54 moves to the slide-withdrawing initial position, the slide tray lifting means 53 is brought to a position at the same height as the guide grooves 321 of the slide tray holding means 32. In the process of ejecting the sheet, after the sheet tray 6 is separated from the sheet tray holding device 32, the sheet tray hooking device 54 drives the cam follower of the sheet tray lifting device 53 to lift the sheet tray 6, and then the sheet tray 6 is placed on the sheet tray placing structure 52 by the sheet tray hooking device 54. At this time, the slicing tray 6 is unhooked from the slicing tray hooking device 54, and the slicing tray 6 completely enters the disc ejecting magazine 51, thereby completing the disc ejecting operation.

Referring to fig. 1 and 2, in the present embodiment, the film feeding magazine 41 includes a first film feeding magazine baffle 411 and a second film feeding magazine baffle 412 that are parallel to each other, and the film withdrawing magazine 51 includes a first film withdrawing magazine baffle 511 and a second film withdrawing magazine baffle 512 that are parallel to each other. The first sheet feeding magazine shutter 411 and the second sheet feeding magazine shutter 412 are respectively provided vertically on the drop guide mechanism 43, and the sheet trays 6 are stacked in the sheet feeding magazine 41. The first and second cassette-withdrawing

baffles

511 and 512 are vertically arranged on the slicing tray arrangement structure 52, and form a cassette-withdrawing cassette with the slicing tray arrangement structure 52 for placing the sliced trays 6 after withdrawing. The bottom of the first plate feeding storage baffle 411 and the bottom of the first plate withdrawing storage baffle 511 are respectively provided with an opening for feeding or withdrawing the plate of the plate-cutting disc 6, and the height of the opening is greater than that of the plate-cutting disc 6.

Referring to fig. 1 to 7, a first embodiment of the present invention is a scanning method of a high-throughput automatic slice scanning system, including the following steps:

s1, system initialization: the microscope system 2, the stage 3, the slide feeder 4 and the slide ejector 5 are each operated to an initial position. Wherein, the xy-motion platform 31 moves to the sheet feeding position, so that the sheet cutting disc clamping device 32 is opposite to the sheet discharging direction of the sheet feeding device 4; the pushing structure 441 of the slide tray feeding mechanism 44 is lower than the bottom surface of the slide tray 6 positioned at the lowest position in the slide feeding library 41, and is attached to the slide pushing structure 64 of the slide tray 6; the initial position of the hooking structure 541 is located at one side of the sheet withdrawing device 5 close to the object stage 3; the initial position of the section tray lifting device 53 is located at the same height as the guide groove 321 of the stage 3.

S2, slicing preparation: the slices to be scanned are fixed on the slice tray 6, and the slice tray 6 is stacked and placed in the slice entry magazine 41.

S3, feeding the film: the slicing disk feeding mechanism 44 pushes the first slicing disk located at the lowest position in the slicing library 41, so that the first slicing disk enters the slicing disk clamping device 32 along the guiding step of the slicing disk mounting guiding structure 42 and is clamped in place, the second slicing disk located above the first slicing disk is blocked by the pushing structure 441 moving to the front end of the second slicing disk and slowly falls onto the slicing disk mounting guiding structure 42, then the slicing disk feeding mechanism 44 retreats, the pushing structure 441 slides through the slicing structure 64 to return to the initial position, the slicing operation of the first slicing disk is completed, and the steps are repeated until all the slicing disks 6 complete the slicing operation.

S4, scanning: the first slice disc is driven by the xy moving platform 31 to move to the position under the microscope system 2, the microscope system 2 automatically finishes focusing, and switches to the corresponding objective lens 24 through the electric objective lens converter 23 to start slice scanning, and the scanning step is repeated until all slice discs 6 finish scanning operation.

S5, withdrawing the tablets: after the slice scanning is completed, the slice tray hooking device 54 drives the slice tray lifting device 53 to be located at the same height position as the bottom surface of the guide groove 321, the xy moving platform 31 drives the slice withdrawing hook groove 63 to be connected with the hooking structure 541, the slice tray hooking device 54 drives the first slice tray to move towards the slice withdrawing device 5 until the first slice tray is completely separated from the slice tray clamping device 32, the slice tray hooking device 54 drives the slice tray lifting device 53 to lift the first slice tray and drive the first slice tray to move to the slice tray arranging structure 52, then the first slice tray and the slice tray hooking device 54 are unhooked, the slice withdrawing operation is completed, and the steps are repeated until all the slice trays 6 complete the slice withdrawing operation.

The above description is only a preferred embodiment of the present invention and is not intended to limit the present invention, and various modifications and changes may be made by those skilled in the art. Any modification, equivalent replacement, or improvement made within the spirit and principle of the present invention should be included in the protection scope of the present invention.

Claims

1. A high-flux automatic slice scanning system is characterized by comprising a base, a microscope system, an object stage, a slice feeding device and a slice withdrawing device;

2. The high throughput automated slide scanning system of claim 1, wherein the lifting device is disposed at a middle portion of the base, the microscope is disposed at a front end of the lifting device, the objective lens interface of the microscope is fixedly disposed with the electric objective lens switching device, the objective lens is disposed on the electric objective lens converter and above the stage, and the electric objective lens switching device is electrically driven to switch the objective lens.

3. The high-throughput automatic slice scanning system according to claim 1, wherein the slice tray holding device is provided with a guide groove adapted to the slice tray, and a plurality of elastic pressing sheets are symmetrically distributed on two sides of the guide groove.

4. The high throughput automatic slice scanning system according to claim 3, wherein the upper surface of the slice tray is provided with a plurality of slice slots for placing slices, each slice slot is provided with at least one elastic pressing sheet, the front end of the slice tray is provided with a slice withdrawing hook slot, the lower surface of the rear end of the slice tray is provided with a push sheet structure, the slice withdrawing hook slot is an open hook slot structure, the push sheet structure is an oblique triangular push sheet structure, and two sides of the slice tray are respectively provided with an avoiding slot adapted to the guide slot.

5. The high throughput automated slice scanning system of claim 4, wherein the slice tray feeding mechanism comprises a pushing structure for abutting the pushing structure and pushing the slice tray to move.

6. The high throughput automatic slice scanning system according to claim 4, wherein the slice tray hooking device is disposed below the middle portion of the slice tray installation structure and below the slice tray lifting device, the slice tray hooking device is further provided with a hooking structure adapted to the slice returning hooking groove, the hooking structure is vertically disposed on the slice tray lifting device, the slice tray lifting device is provided with a cam follower, and the cam follower is driven by the slice tray hooking device to lift the slice tray.

7. The high throughput automated slice scanning system of claim 1, wherein the slice tray placement guide comprises two symmetrically disposed two-step structures with small step slope angles.

8. The high throughput automatic slice scanning system according to claim 7, wherein the falling guide mechanism comprises falling guide arms respectively disposed at two sides of the slice tray feeding mechanism, the two falling guide arms are respectively provided with a secondary step structure on inner sidewalls thereof, the falling guide arms are further provided with a plurality of spring pins at equal intervals on the inner sidewalls thereof, and the spring pins are disposed above the secondary step structure.

9. The high-throughput automatic slice scanning system according to claim 1, wherein the slice feeding magazine comprises a first slice feeding magazine baffle and a second slice feeding magazine baffle which are parallel to each other, the slice returning magazine comprises a first slice returning magazine baffle and a second slice returning magazine baffle which are parallel to each other, the first slice feeding magazine baffle and the second slice feeding magazine baffle are respectively and vertically arranged on the falling guide mechanism, the first slice returning magazine baffle and the second slice returning magazine baffle are vertically arranged on the slice tray arrangement structure, an opening for feeding or returning slices to the slice tray is respectively arranged at the bottom of the first slice feeding magazine baffle and the bottom of the first slice returning magazine baffle, and the height of the opening is greater than the height of the slice tray.