CN212120396U

CN212120396U - Centrifugal separation device for protease production

Info

Publication number: CN212120396U
Application number: CN202020414423.9U
Authority: CN
Inventors: 王仁
Original assignee: Nanjing Yongzheng Biotechnology Co ltd
Current assignee: Nanjing Yongzheng Biotechnology Co ltd
Priority date: 2020-03-27
Filing date: 2020-03-27
Publication date: 2020-12-11
Anticipated expiration: 2030-03-27

Abstract

The utility model discloses a centrifugal separation device for protease production, fight first including the centrifugation, centrifugation is fought two, the kuppe, collect liquid fill and agitating unit, the kuppe cover is established in the outside that centrifugation was fought one, still be provided with the opening at the top of kuppe, centrifugation is fought two settings in the inside of collecting liquid fill, the bottom opening of kuppe extends to the internal of bucket that centrifugation was fought two, and be provided with the shrouding that is used for being connected between the top of kuppe and collecting liquid fill, be provided with the apron on the opening at kuppe top, be provided with the inlet pipe on the apron, the bottom of collecting liquid fill is provided with a plurality of support, still be provided with the drain pipe in the bottom of collecting liquid fill, agitating unit includes from top to bottom alternates in proper order and has collected liquid fill, centrifugation is fought two and extends to the pivot of centrifugation fill one inside and set up the drive arrangement that is used for, And centrifugal propellers are arranged on the rotating shafts of the centrifugal hoppers II. The utility model discloses show the purity that has improved the protease of centrifugal separation.

Description

Centrifugal separation device for protease production

Technical Field

The utility model relates to a centrifugal separation device for protease production belongs to the centrifugal separation device field.

Background

In the production process of the protease, the protease needs to be centrifugally separated out and collected by using a centrifugal separation device. However, most of the existing centrifugal separation devices are operated by single centrifugal separation, the purity of the separated protease is low, the required purity can be achieved only by separating again, and the efficiency is reduced.

Disclosure of Invention

For solving prior art's not enough, the utility model provides a centrifugal separation device for protease production, through the further centrifugal separation of protease to preliminary centrifugal separation, improved the purity of the protease of centrifugal separation, improved efficiency.

The utility model discloses the technical scheme who adopts does:

a centrifugal separation device for protease production comprises a first centrifugal hopper, a second centrifugal hopper, a flow guide cover, a liquid collecting hopper and a stirring device, wherein the flow guide cover is arranged outside the first centrifugal hopper, the top of the first centrifugal hopper is fixed with the top of the flow guide cover through a fixing column, an opening is further formed in the top of the flow guide cover, the second centrifugal hopper is arranged inside the liquid collecting hopper and is fixed with the liquid collecting hopper through a plurality of fixing blocks, the diameter of the upper opening of the second centrifugal hopper is larger than that of the upper opening of the first centrifugal hopper, the bottom opening of the flow guide cover extends into a hopper body of the second centrifugal hopper, a sealing plate used for connection is arranged between the flow guide cover and the top of the liquid collecting hopper, a cover plate is arranged on the opening in the top of the flow guide cover, a feeding pipe is arranged on the cover plate, a plurality of supports are arranged at the bottom of the liquid collecting hopper, a liquid outlet pipe is further arranged at the bottom, The centrifugal bucket II extends to a rotating shaft inside the centrifugal bucket I and a driving device which is arranged at the bottom of the liquid collecting bucket and is used for driving the rotating shaft to rotate, and centrifugal propellers are arranged on the rotating shafts of the centrifugal bucket I and the centrifugal bucket II.

Preferably, the rotating shaft, the centrifugal hopper I, the centrifugal hopper II and the liquid collecting hopper are all mechanically sealed.

Further preferably, the bottom of the first centrifugal hopper is higher than the sealing plate.

Preferably, one side of the body of the first centrifugal hopper is provided with a first liquid discharge pipe which penetrates through the air guide sleeve and extends to the upper part of the sealing plate, and the bottom of the body of the second centrifugal hopper is provided with a second liquid discharge pipe which penetrates through the liquid collecting hopper and extends to the outer side of the liquid collecting hopper.

Preferably, valves are provided on both the first drain pipe located above the sealing plate and the second drain pipe extending to the outside of the collecting hopper.

Further preferably, the feed pipe and the liquid outlet pipe are also provided with valves.

The beneficial effects of the utility model reside in that:

through stirring with the preliminary centrifugal separation of the protease in the centrifugal hopper one and flow to the centrifugal hopper two in through the kuppe and carry out the centrifugal separation once more in, discharge after collecting through the collecting hopper, improved the purity of the protease of centrifugal separation, avoided the centrifugation once more operation to the low protease of purity, improved work efficiency.

Drawings

Fig. 1 is a schematic structural view of the present invention;

the main reference numerals in the figures have the following meanings:

1. the centrifugal device comprises a first centrifugal bucket, a second centrifugal bucket, a third centrifugal bucket, a fourth centrifugal.

Detailed Description

The present invention will be described in detail with reference to the accompanying drawings and examples.

As shown in fig. 1: the embodiment is a centrifugal separation device for protease production, which comprises a centrifugal bucket I1, a centrifugal bucket II 2, a flow guide cover 3, a liquid collecting bucket 4 and a stirring device, wherein the flow guide cover 3 is covered outside the centrifugal bucket I1, the top of the centrifugal bucket I1 is fixed with the top of the flow guide cover 3 through a fixing column 5, the top of the flow guide cover 3 is also provided with an opening, the centrifugal bucket II 2 is arranged inside the liquid collecting bucket 4 and is fixed with the liquid collecting bucket 4 through a plurality of fixing blocks 6, the diameter of the upper opening of the centrifugal bucket II 2 is larger than that of the upper opening of the centrifugal bucket I1, the bottom opening of the flow guide cover 3 extends into a bucket body of the centrifugal bucket II 2, a sealing plate 7 for connection is arranged between the flow guide cover 3 and the top of the liquid collecting bucket 4, a cover plate 8 is arranged on the opening at the top of the flow guide cover 3, a feeding pipe 9 is arranged on the cover plate 8, a plurality of supports, still be provided with drain pipe 11 in the bottom of collecting hopper 4, agitating unit is including from top to bottom interlude collecting hopper 4, centrifugal fill two 2 in proper order and extend to the inside pivot 12 of centrifugal fill 1 and set up the drive arrangement 13 that is used for driving pivot 12 pivoted in collecting hopper 4 bottom, all is provided with centrifugal propeller 14 on the pivot 12 that lies in centrifugal fill 1, centrifugal fill two 2.

In this embodiment, the rotating shaft 12, the centrifugal hopper 1, the centrifugal hopper 2, and the liquid collecting hopper 4 are all mechanically sealed.

Referring to fig. 1, the bottom of the first centrifugal hopper 1 is higher than the sealing plate 7; and one side of the body of the first centrifugal bucket 1 is provided with a first liquid discharge pipe 15 which penetrates through the air guide sleeve 3 and extends to the upper part of the sealing plate 7, and the bottom of the body of the second centrifugal bucket 2 is provided with a second liquid discharge pipe 16 which penetrates through the liquid collecting bucket 4 and extends to the outer side of the liquid collecting bucket 4.

In this embodiment, valves are disposed on the first drain pipe 15 located above the sealing plate 7 and the second drain pipe 16 extending to the outside of the collecting hopper 4; the inlet pipe 9 and the outlet pipe 11 are also provided with valves.

The utility model discloses in the in-service use, it treats centrifugal solution to carry in fighting one 1 with the centrifugation through feed liquor pipe 9 on the apron 8, under drive arrangement 13's drive, pivot 12 drives centrifugal propeller 14 and rotates, it carries out centrifugal separation to treating centrifugal solution that falls into in fighting one 1 to be located centrifugal propeller 14 of fighting one 1, go out protease liquid from the top separation, under kuppe 3's effect, protease liquid after the initial gross separation falls to fighting two 2 in the centrifugation, liquid level in fighting two 2 constantly rises, and under centrifugal propeller 14 effect in fighting two 2 in the centrifugation, further centrifugation to protease liquid of initial centrifugal separation, protease liquid of centrifugal separation once more flows to collecting and fights in 4 and finally through drain pipe 11 discharges the collection through the top of fighting two 2 in the centrifugation, the purity of the protease of centrifugal separation has been improved.

The above description is only a preferred embodiment of the present invention, and it should be noted that, for those skilled in the art, a plurality of improvements and decorations can be made without departing from the principle of the present invention, and these improvements and decorations should also be regarded as the protection scope of the present invention.

Claims

1. A centrifugal separation device for protease production, characterized in that: comprises a first centrifugal hopper (1), a second centrifugal hopper (2), a flow guide cover (3), a liquid collecting hopper (4) and a stirring device, wherein the flow guide cover (3) is covered outside the first centrifugal hopper (1), the top of the first centrifugal hopper (1) is fixed with the top of the flow guide cover (3) through a fixing column (5), the top of the flow guide cover (3) is also provided with an opening, the second centrifugal hopper (2) is arranged inside the liquid collecting hopper (4) and is fixed with the liquid collecting hopper (4) through a plurality of fixing blocks (6), the diameter of the upper opening of the second centrifugal hopper (2) is larger than that of the first centrifugal hopper (1), the opening at the bottom of the flow guide cover (3) extends into the hopper body of the second centrifugal hopper (2), a sealing plate (7) for connection is arranged between the flow guide cover (3) and the top of the liquid collecting hopper (4), and a cover plate (8) is arranged on the opening at the top of the flow guide cover (3), be provided with inlet pipe (9) on apron (8), the bottom of collecting hopper (4) is provided with a plurality of support (10), still is provided with drain pipe (11) in the bottom of collecting hopper (4), agitating unit is including from top to bottom alternating collecting hopper (4), centrifugal hopper two (2) and extending to centrifugal hopper one (1) inside pivot (12) and setting up being used for driving pivot (12) pivoted drive arrangement (13) in collecting hopper (4) bottom in proper order, all is provided with centrifugal screw (14) on pivot (12) that lie in centrifugal hopper one (1), centrifugal hopper two (2).

2. The centrifugal separation device for protease production according to claim 1, wherein the rotating shaft (12) and the centrifugal buckets I (1), II (2) and 4 are mechanically sealed.

3. The centrifugal separation device for protease production according to claim 1, wherein the height of the bottom of the first centrifugal hopper (1) is higher than that of the sealing plate (7).

4. The centrifugal separation device for protease production according to claim 3, wherein the first centrifugal hopper (1) is provided with a first drain pipe (15) on one side of the hopper body, which penetrates through the air guide sleeve (3) and extends to the upper part of the sealing plate (7), and the second centrifugal hopper (2) is provided with a second drain pipe (16) on the bottom of the hopper body, which penetrates through the liquid collecting hopper (4) and extends to the outer side of the liquid collecting hopper (4).

5. A centrifugal separator for use in protease production according to claim 4 wherein valves are provided on the first drain (15) located above the sealing plate (7) and the second drain (16) extending outside the hopper (4).

6. A centrifugal separator for use in the production of proteases according to claim 1, wherein the inlet (9) and outlet (11) pipes are also provided with valves.