CN211024414U - ECMO closed pre-charging device - Google Patents

Abstract

The utility model relates to the field of medical equipment, a ECMO closed preflush device is disclosed, including ECMO device and with the accurate infusion external member of ECMO device intercommunication, the ECMO device includes ECMO machine, centrifugal pump, membrane lung exit end to the drainage tube of centrifugal pump entry end, centrifugal pump exit end to the drainage tube of membrane lung entry end and two interfaces on the drainage tube of membrane lung exit end to the centrifugal pump entry end, accurate infusion external member includes backward flow bag and preflush bag, and this preflush bag and backward flow bag pass through the passageway intercommunication, and this passageway is equipped with filter head and one-way check valve, and the preflush bag even is equipped with the ECMO preflush pipe of connecting two interfaces respectively with backward flow bag lower part. The utility model discloses a filter head destroys intraductal preflush liquid bubble, and the preflush liquid circulates in advance through one-way check valve after, realizes the pipeline preflush of ECMO device, replaces air and bubble in the pipeline, save time, pollution abatement, and the preflush thoroughly, guarantees that ECMO effectively implements, strives for the time for rescuing the patient.

Description

ECMO closed pre-charging device

Technical Field

The utility model relates to the field of medical equipment, especially, relate to an ECMO closed pre-charging device.

Background

Extracorporeal membrane pulmonary oxygenation (ECMO) is a technique for rescuing patients with severe cardiopulmonary failure, represents a critical illness rescue level in a country, region, hospital, and even currently considers that ECMO techniques redefine the boundary between life and death. ECMO is an extracorporeal circulation technology which is taken out of a heart operating room, and the principle of the ECMO is that venous blood in a human body is led out of the human body and is injected into an artery or vein system of a patient after being oxygenated by an artificial heart-lung bypass made of special materials, so that a partial heart-lung replacement effect is achieved, and the oxygenation blood supply of visceral tissues of the human body is maintained.

The basic structure of the ECMO includes an intravascular cannula, a connecting tube, a centrifugal pump (artificial heart), an oxygenator (artificial lung), an oxygen supply tube, and a monitoring system. The disposable part is usually formed into a kit clinically, and the non-disposable part is stored in a binding way and is designed to be movable, so that the emergency capacity is improved.

The membrane lung functions to synthesize oxygenated blood from non-oxygenated blood oxygen, also known as the artificial lung. The ECMO oxygenator has two types, namely a silica gel membrane type and a hollow fiber type. The silica gel membrane type membrane lung has good compatibility, less plasma leakage and less damage to blood components, and is suitable for long-time assistance. For example, supporting heart and lung function awaiting transplantation, respiratory failure due to infection. The disadvantages are difficult and expensive exhaust. The hollow fiber type membrane lung is easy to exhaust, plasma leakage can be seen in 2-3 days, and blood components are relatively damaged, but the hollow fiber type membrane lung is still preferably used as a first-aid kit due to simple installation. If necessary, the appropriate oxygenator may be replaced within one to two days after a stable condition.

The centrifugal pump functions to create a motive force to drive blood flow to one side of the conduit, similar to the function of the heart. There are two main types of centrifugal pumps in clinical practice: roller pumps, centrifugal pumps. Because the roller pump is difficult to move and manage, the centrifugal pump is the first choice in the emergency department as the centrifugal pump. The blood transfusion device has the advantages of convenient installation and movement, convenient management and small blood damage; the suction effect is realized in a reasonable negative pressure range, and the problem of low flow caused by some reasons can be solved; the centrifugal pump of the new generation is easy to control the low flow of the children.

With the progress of technology, ECMO is used more and more in critical diseases, but the pre-filling of a pipeline is required before the ECMO is used, and if the pre-filling and air-exhausting are not complete, air embolism can be generated, membrane lung coagulation is caused, and the life of a patient is threatened. Meanwhile, the one-time pre-filling is not thorough, the time consumption of the second pre-filling is increased, the cost of patients is increased, and the like, so that the timely and effective application of the ECMO is influenced.

SUMMERY OF THE UTILITY MODEL

The utility model provides a solve above-mentioned problem, provide a ECMO closed pre-charging device, this pre-flushing device can destroy intraductal pre-flushing liquid bubble through the filter head, can circulate the pre-flushing after the pre-flushing liquid leads to filter head and one-way check valve, only needs a small amount of pre-flushing liquid can realize the pipeline pre-flushing with the ECMO device, replaces air and bubble in the pipeline.

In order to achieve the above object, the ECMO closed precharge device of the present invention is communicated with an ECMO device, the ECMO device includes an ECMO machine, a centrifugal pump, a membrane lung, a first drainage tube from an outlet end of the membrane lung to an inlet end of the centrifugal pump, a second drainage tube from an outlet end of the centrifugal pump to an inlet end of the membrane lung, and a first interface and a second interface on the first drainage tube from the outlet end of the membrane lung to the inlet end of the centrifugal pump;

a precision infusion set connected to the ECMO apparatus, the precision infusion set comprising a reflux bag and a priming bag;

the pre-flushing bag is communicated with the backflow bag through a channel, the channel is provided with a filter head and a one-way check valve, the lower part of the pre-flushing bag is provided with a first ECMO pre-flushing pipe which is connected with a first interface on a drainage pipe from the outlet end of the membrane lung to the inlet end of the centrifugal pump, and the lower part of the backflow bag is provided with a second ECMO pre-flushing pipe which is connected with a second interface on the drainage pipe from the outlet end of the membrane lung to the inlet end of;

the filter head is used for destroying bubbles in the pre-flushing liquid;

the clamp part comprises a first vascular clamp, a second vascular clamp, a third vascular clamp and a fourth vascular clamp;

the first vascular clamp is arranged on the first ECMO drainage tube between the first interface and the second interface, and the first vascular clamp can prevent the pre-flush liquid flowing out from the membrane lung outlet end from returning to the inlet end of the centrifugal pump after being clamped;

the second vessel clamp is arranged on a second drainage tube from the outlet end of the centrifugal pump to the inlet end of the membrane lung and is used for clamping a pipeline at the position when the ECMO machine is started up/shut down;

the third vascular clamp is arranged on the ECMO pre-flushing pipe II at the lower part of the reflux bag;

the fourth vascular clamp is arranged on the first ECMO pre-flushing pipe at the lower part of the pre-flushing bag, and the third vascular clamp and the fourth vascular clamp can close/open the flow of the pre-flushing liquid.

Preferably, the filter head is positioned on a channel for communicating the backflow bag and the pre-flushing bag and is fixedly connected with the one-way check valve.

Preferably, the filter head is a hollow structure consisting of an outlet end, an inlet end and a side wall extending therebetween, and the side wall of the filter head is provided with a plurality of filter holes penetrating along the direction of the side wall.

Preferably, the diameter of the filtering hole is 0.3-0.6 mm, and the length of the filtering hole is 5-8 mm.

Preferably, the filter head is of a boss type hollow structure, the left end of the filter head is an inlet end connected with a backflow bag, the right end of the filter head is an outlet end connected with a one-way check valve, and the diameter of an opening at the inlet end of the left end of the filter head is larger than that of an opening at the outlet end of the right end of the filter head.

Preferably, the one-way check valve is a one-way valve body, the pre-flushing liquid entering the filter head can only enter the pre-flushing bag through the one-way check valve, and the pre-flushing liquid in the pre-flushing bag cannot directly enter the backflow bag through the one-way check valve.

Preferably, the first connector and the second connector are provided with internal threads, and one end of the second ECMO preflushing pipe at the lower part of the backflow bag and one end of the first ECMO preflushing pipe at the lower part of the preflushing bag are both provided with external threads;

preferably, the external thread of the first ECMO preflushing pipe at the lower part of the preflushing bag can be connected with the internal thread of the first connector, and the external thread of the second ECMO preflushing pipe at the lower part of the backflow bag can be connected with the internal thread of the second connector.

Preferably, puncture needles are arranged at the other end of the second ECMO pre-washing pipe at the lower part of the backflow bag and the other end of the first ECMO pre-washing pipe at the lower part of the pre-washing bag and are used for connecting the pre-washing bag and the backflow bag.

Preferably, the height of the channel for communicating the pre-flushing bag and the backflow bag, the filter head and the one-way check valve is positioned on the same horizontal plane and is positioned at 1/3-1/4 of the height of the pre-flushing bag.

Preferably, the bottom surfaces of the pre-flush bag and the return bag are the same size, and the volume of the return bag is not more than half of the volume of the pre-flush bag.

The utility model has the advantages that: use the utility model discloses a device, the utility model discloses a centrifugal pump is with the preflushing liquid pump to the backward flow bag of preflushing bag, forms the preflushing to the ECMO pipeline, and when the height of the high surpass filter head of the preflushing liquid in the backward flow bag, the preflushing liquid of backward flow bag leads to filter head and one-way check valve and gets into the preflushing bag, destroys through the bubble interception of filter head in to the preflushing liquid simultaneously for in the difficult entering ECMO pipeline of bubble, and the preflushing liquid can be at the pipeline mesocycle. The utility model discloses whole preflushing is gone on under airtight environment, has removed the tube drawing intubate when changing the preflushing bag in traditional preflushing from, and whole operation process is aseptic, compares this preflushing more thoroughly, but save time, pollution abatement with traditional method, can guarantee the effective implementation of ECMO, improves work efficiency, strives for the time for rescuing the patient, practices thrift the cost.

Drawings

Fig. 1 is a schematic view of an ECMO closed preflush apparatus according to a preferred embodiment of the present invention;

FIG. 2 is a cross-sectional view of the filter head of the present invention;

FIG. 3 is a cross-sectional view of a preferred embodiment of the precision infusion set of the present invention;

description of the reference numerals

1-centrifugal pump, 2-membrane lung, 3-drainage tube I, 31-connector I, 32-connector II, 4-drainage tube II, 5-preflushing bag, 51-ECMO preflushing tube I, 6-backflow bag, 61-ECMO preflushing tube II, 7-channel, 71-filter head, 711-outlet end, 712-inlet end, 713-side wall 713, 714-filtering hole, 72-one-way check valve, 81-first vessel clamp, 82-second vessel clamp, 83-third vessel clamp and 81-fourth vessel clamp.

Detailed Description

The present invention will be described in detail with reference to the accompanying drawings and specific embodiments. It is to be understood that the description of the embodiments herein is for purposes of illustration and explanation only and is not intended to limit the invention.

Referring to fig. 1, 2 and 3, the present invention provides an ECMO hermetic precharge device for precharging an ECMO device.

The utility model discloses an ECMO improvement closed pre-charge device communicates with ECMO device, ECMO device includes ECMO machine, centrifugal pump 1, membrane lung 2 among the prior art, 2 exit ends of membrane lung to the drainage tube 3 of centrifugal pump 1 entry end, the drainage tube two 4 of 1 exit ends of centrifugal pump to 2 entry ends of membrane lung and the interface one 31 and the interface two 32 on the drainage tube 3 of 2 exit ends of membrane lung to centrifugal pump 1 entry end;

the ECMO closed pre-filling device also comprises a precise infusion set connected with the ECMO device, wherein the precise infusion set comprises a reflux bag 6 and a pre-filling bag 5;

the pre-flushing bag 5 is communicated with the backflow bag 6 through a channel 7, the channel 7 is provided with a filter head 71 and a one-way check valve 72, the lower part of the pre-flushing bag 5 is provided with a first ECMO pre-flushing pipe 51 which is connected with a first interface 31 on a first drainage pipe 3 from an outlet end of a membrane lung 2 to an inlet end of the centrifugal pump 1, the lower part of the backflow bag 6 is provided with a second ECMO pre-flushing pipe 61 which is connected with a second interface 32 on the first drainage pipe 3 from the outlet end of the membrane lung 2 to the inlet end of the centrifugal pump 1, and the pre-flushing;

the filter head 71 is used for destroying air bubbles in the pre-flushing liquid, the filter head 71 is provided with filter holes 714, the filter holes 714 are communicated with the interior of the filter head 71, the backflow bag 6 and the one-way check valve 72, and when the pre-flushing liquid passes through the filter holes 714 of the filter head 71, the air bubbles in the pre-flushing liquid can be destroyed.

The ECMO closed type priming device of the utility model is also provided with a clamp part which comprises a first vascular clamp 81, a second vascular clamp 82, a third vascular clamp 83 and a fourth vascular clamp 84;

the first vascular clamp 81 is arranged on the first ECMO drainage tube 3 between the first connector 31 and the second connector 32, and the pre-flush liquid flowing out from the outlet end of the membrane lung 2 is prevented from returning to the inlet end of the centrifugal pump 1 after the first vascular clamp 81 is clamped.

The second vascular clamp 82 is arranged at the second drainage tube 4 from the outlet end of the centrifugal pump 1 to the inlet end of the membrane lung 2, and the second vascular clamp 82 clamps the second drainage tube 4 when the ECMO machine is started up/shut down;

the third vascular clamp 83 is arranged on the second ECMO pre-flushing pipe 61 at the lower part of the backflow bag 6, the fourth vascular clamp 84 is arranged on the first ECMO pre-flushing pipe 51 at the lower part of the pre-flushing bag 5, and the third vascular clamp 83 and the fourth vascular clamp 84 can close/open the flow of the pre-flushing liquid.

Use the utility model discloses when dashing in advance the ECMO pipeline, will dash in advance the liquid in the bag 5 through 1 work of centrifugal pump and flow back to backward flow bag 6 through centrifugal pump 1, membrane lung 2, when the long-pending height of surpassing filter head 71 of the liquid that dashes in advance in the bag 6 that flows back, the liquid that dashes in advance gets into in advance bag 5 through filter head 71, one-way check valve 72 to the realization is to the circulation of ECMO device dashing in advance.

The first vascular clamp 81 clamps closed so that the return bag 6, the priming bag 5 and the channel 8 connecting the priming bag 5 and the return bag 6 form a circulatory priming bypass for replacing the section of the pipeline.

The filter head 71 is a hollow structure composed of an outlet end 711, an inlet end 712 and a side wall 713 extending between the outlet end 711 and the inlet end 712, the side wall 713 of the filter head 71 is provided with a plurality of filter holes 714 penetrating along the direction of the side wall, and the filter holes 714 are communicated with the inside of the filter head 71, the backflow bag 6 and the one-way check valve 72.

The filter head 71 is a boss hollow structure with a big end and a small end, wherein the big end is a pre-flushing inlet 712, and the small end is a pre-flushing outlet 711; the one-way check valve 72 is a one-way valve body, so that the pre-flushing liquid entering the filter head 71 can only enter the pre-flushing bag 5 through the one-way check valve 72, and the pre-flushing liquid in the pre-flushing bag 5 cannot directly enter the backflow bag 6 through the one-way check valve 72.

The utility model discloses an in the preferred embodiment, should filter the diameter of hole 714 and be 0.3 ~ 0.6mm, filter the length of hole 714 and be 5 ~ 8mm, can filter the bubble in the pre-flush liquid for the bubble breaks behind the filter head 71.

Referring to fig. 3, in a preferred embodiment of the present invention, the channel 7, the filter head 71 and the one-way check valve 72, which communicate the pre-washing bag 5 and the backflow bag 6, are located at 1/4 of the height of the pre-washing bag 5 on the same horizontal level, and when the height of the pre-washing liquid in the pre-washing bag 5 decreases to be not less than the height of the filter head 71, the height of the pre-washing liquid in the backflow bag 6 exceeds the height of the filter head 71 or the pre-washing liquid fills the backflow bag 6, so as to realize the circulation pre-washing of the pre-washing liquid.

The filter head 71 is of a boss type hollow structure, the left end of the filter head 71 is an inlet end 712 connected with the backflow bag 6, the right end of the filter head 71 is an outlet end 711 connected with the one-way check valve 72, and the opening diameter of the inlet end 712 at the left end of the filter head 71 is larger than that of the outlet end 711 at the right end.

The one-way check valve 72 is a one-way valve body, so that the pre-flushing liquid entering the filter head 71 can only enter the pre-flushing bag 5 through the one-way check valve 72, and the pre-flushing liquid in the pre-flushing bag 5 cannot directly enter the backflow bag 6 through the one-way check valve 72.

In current ECMO device, be equipped with the internal thread on interface one 31 and the two 32, the utility model discloses an in the preferred embodiment, ECMO of backward flow bag 6 lower part washes in advance pipe two 61 and the ECMO of the bag 5 lower part of dashing in advance and manages a 51 exit in advance and all be equipped with the external screw thread, will wash in advance ECMO of bag 5 lower part in advance and manage a 51 external screw thread and interface one 31's female connection, the ECMO of backward flow bag 6 lower part washes in advance the external screw thread of pipe two 61 and the female connection of interface two 32, has realized the quick intercommunication of accurate infusion external member and ECMO pipeline.

The utility model discloses an among the preferred embodiment, the ECMO of backward flow bag 6 lower part is towards the other end of pipe two 61 in advance and is equipped with the plastic steel needle on the ECMO of bag 5 lower part in advance towards the other end of pipe 51 in advance, can directly peg graft fast and in advance towards bag 5 and backward flow bag 6, realize ECMO and dash a pipe 51 in advance and dash the quick connection of bag 5 in advance, ECMO dashes the quick connection of pipe two 61 and backward flow bag 6 in advance.

In a preferred embodiment of the present invention, the reflow bag 6 and the pre-punching bag 5 can be processed into a bottle shape or a bag shape, and the bottom surface of the reflow bag 6 has the same size as the pre-punching bag 5; and/or the volume of the backflow bag 6 is not more than half of the volume of the pre-flushing bag 5, the volume relation between the pre-flushing bag 5 and the backflow bag 6 meets the condition that the volume descending height of the pre-flushing liquid in the pre-flushing bag 5 is not less than the height of the filter head 71, and the height of the pre-flushing liquid in the backflow bag 6 is higher than the height of the filter head 71, so that the pre-flushing liquid circulation pre-flushing can be ensured.

In a preferred embodiment of the present invention, the pre-flushing with the ECMO closed pre-flushing device comprises the following steps:

s1, preparing an ECMO prepunching object and an ECMO machine, and ensuring that the ECMO machine is in a complete state;

s2, preparing ECMO pre-flushing liquid, and adding the pre-flushing liquid into a pre-flushing bag 5 of the precise infusion set;

s3, connecting each part of the ECMO device and the pre-punching device;

s4, removing air in a pipeline of a drainage tube I3 at the inlet end of the centrifugal pump 1 and air in a pump head of the centrifugal pump 1 by using the principle of gravity;

s5, pre-flushing by using the centrifugal pump 1;

and S6, finishing the pre-flushing, finishing the built-in tube of the patient body, and opening the ECMO (electron cyclotron resonance) sleeve bag to be connected with the built-in tube of the patient body.

Step S1 includes preparing ECMO machine, vascular clamp, coupling agent, ringer' S solution 700-; the instrument is confirmed to be in a good standby state by connecting an ECMO power supply, an oxygen source and a gas source.

Step S2 includes dispensing 700 & 800ml of ringer' S solution into the pre-filling bag 5 of the precision infusion set, inserting the puncture needle of the first ECMO pre-filling tube 51 into the pre-filling bag 5, inserting the puncture needle of the second ECMO pre-filling tube 61 into the return bag 6, and keeping the first ECMO pre-filling tube 51 and the second ECMO pre-filling tube 61 suspended on the ECMO infusion support in a sterile manner.

Step S3 is the connection of an ECMO device and a pre-flushing device, firstly, an ECMO sleeve bag is opened, a first drainage tube 3 is connected with the inlet end of a centrifugal pump 1 and is fixed by a self-locking binding belt, a first interface 31 and a first ECMO pre-flushing tube 51 are in threaded connection, a membrane lung 2 is arranged on an ECMO fixing frame, an oxygen source and an air source are connected, a temperature-changing water tank is opened at the same time, sterilization injection water is added and does not exceed a water level line, the temperature is set to be 35-37 ℃, pressure extension tubes at two ends of an oxygenator of the ECMO machine are connected, the outlet end of the membrane lung 2 is connected with the other end of the first drainage tube 3, and a second; after connection, the smooth pipeline is confirmed, all devices are connected firmly, and then the ECMO drainage tube I3 between the first connector 31 and the second connector 32 is clamped by a first vascular clamp 81, wherein the clamping position is close to the inlet end of the centrifugal pump 1.

Step S4 includes S41, opening a third vascular clamp 83 and a fourth vascular clamp 84, enabling the pre-flushing liquid to flow into a first drainage tube 3 pipeline at the inlet end of the centrifugal pump 1 due to self gravity, and removing air in a first drainage tube 3 at the front end of the centrifugal pump 1 and a first ECMO pre-flushing tube 51 at the bottom of the pre-flushing bag 5 by matching with the vascular clamps;

s42, reversely exhausting air by using the vascular forceps again, exhausting air in the centrifugal pump 1 to the full to ensure that the second vascular forceps 82 clamp a second 4 pipeline of the drainage tube between the centrifugal pump 1 and the membrane lung 2 before the pre-flushing liquid reaches the membrane lung 2;

thus, in the first priming in step S41, the first drainage tube 3 is connected to the centrifugal pump 1, after the first connector 31 is in threaded connection with the first ECMO priming tube 51, the fourth vascular clamp 84 is opened, the air in the first drainage tube 3 at the front end of the centrifugal pump 1 and the first ECMO priming tube 51 at the bottom of the priming bag 5 is discharged faster by using the gravity, and when the centrifugal pump 1 is filled with the priming liquid, the outlet end of the centrifugal pump 1 is communicated with the inlet end of the membrane lung 2 through the second drainage tube 4, so that the priming time can be shortened.

Step S5 includes S51. coating coupling agent on the end of the centrifugal pump 1 and then loading the coupling agent into a driving device of the centrifugal pump 1 of the ECMO machine;

s52, instrument zeroing: the instrument is started for self-checking, the main switch of the instrument is always kept in an ON state, a return-to-0 key is pressed for a long time, four 0 s appear ON a screen, and the return-to-zero is successful;

s53, regulating the rotation speed of the centrifugal pump 1 to 1500, opening a second vascular clamp 82 at the outlet of the pump head of the centrifugal pump 1, regulating the rotation speed of the centrifugal pump 1 to 2500, and paying attention to the liquid levels in the backflow bag 6 and the pre-flushing bag 5; checking whether bubbles remain in each joint in the pre-filling process, fastening each joint, and simultaneously removing air from interfaces at the two ends of the pressure extension pipes, the front film and the rear film and the upper film;

s54, when the heights of the pre-flushing liquid in the backflow bag 6 and the pre-flushing bag 5 are higher than that of the filter head 71, the ECMO starts to remove residual air bubbles in the pipeline in a self-circulation mode, and the fact that no air bubbles exist in the pipeline is confirmed again.

Step S6 includes: s61, regulating the rotation speed of the centrifugal pump 1 to 1500, clamping a second 4 pipeline of a drainage tube at the outlet end of the centrifugal pump 1 by using a second vascular clamp 82, immediately regulating the rotation speed to 0, removing the second 61 ECMO pre-flushing tube and the first 51 ECMO pre-flushing tube, connecting a first connector 31 and a second connector 32 by using a heparin cap, then regulating the rotation speed to 1500, simultaneously loosening the first vascular clamp 81 and the second vascular clamp 82, and starting self-circulation of the instrument;

s62, placing the arterial cannula and the venous cannula, stopping the ECMO machine, opening the sleeve packaging bag, delivering the pipeline to a doctor on the table in an aseptic environment, straightening the whole circulation pipeline, and fixing the pipeline at a proper position.

In the pre-flushing process of the utility model, the air in the ECMO pipeline is replaced by the pre-flushing liquid in the precise infusion set, and the bubbles in the pre-flushing liquid are destroyed by the interception of the filter head 71, so that the circularly flowing pre-flushing liquid does not contain air, and the air in the ECMO pipeline can be removed through repeated circulating pre-flushing; the pre-flushing liquid in the pre-flushing bag 5 is pumped into the backflow bag 6 and then flows back into the pre-flushing bag 5 through the channel 7, and the whole pre-flushing liquid can flow circularly.

The utility model discloses whole preflushing is gone on under airtight environment, has avoided traditional preflushing in-process tube drawing intubate to cause the not thorough problem of preflushing, and whole operation process is aseptic, compares this preflushing more thoroughly with traditional method, but save time, pollution abatement and reduce complication emergence probability such as membrane lung coagulation, air embolism, can guarantee the effective implementation of ECMO, improves work efficiency, for the rescue patient time of striving for, practice thrift the cost.

The above is the preferred embodiment of the present invention, explain the basic structure, operation method and advantages of the present invention, however, the present invention is not limited thereto, the technical idea of the present invention is in the scope, can be right the technical solution of the present invention performs multiple simple variants, including each technical feature combined with any other suitable mode, these simple variants and combinations should be considered as the present invention discloses, all belong to the protection scope of the present invention.

Claims (10)

1. An ECMO pre-fill apparatus, comprising:

the ECMO device comprises an ECMO machine, a centrifugal pump (1), a membrane lung (2), a first drainage tube (3) from the outlet end of the membrane lung (2) to the inlet end of the centrifugal pump (1), a second drainage tube (4) from the outlet end of the centrifugal pump (1) to the inlet end of the membrane lung (2), and a first interface (31) and a second interface (32) on the first drainage tube (3) from the outlet end of the membrane lung (2) to the inlet end of the centrifugal pump (1);

a precision infusion set connected to the ECMO apparatus, the precision infusion set comprising a reflux bag (6) and a priming bag (5);

the pre-flushing bag (5) is communicated with the backflow bag (6) through a channel (7), the channel (7) is provided with a filter head (71) and a one-way check valve (72), the lower part of the pre-flushing bag (5) is provided with a first ECMO pre-flushing pipe (51) which is used for connecting the outlet end of the membrane lung (2) to a first interface (31) on a first drainage pipe (3) at the inlet end of the centrifugal pump (1), and the lower part of the backflow bag (6) is provided with a second ECMO pre-flushing pipe (61) which is used for connecting the outlet end of the membrane lung (2) to a second interface (32) on the first drainage pipe (3) at the inlet end;

the filter head (71) is used for destroying bubbles in the pre-flushing liquid;

a clamp portion comprising a first vascular clamp (81), a second vascular clamp (82), a third vascular clamp (83), and a fourth vascular clamp (84);

the first vascular clamp (81) is arranged on the ECMO drainage tube I (3) between the interface I (31) and the interface II (32), and the pre-flushing liquid flowing out from the outlet end of the membrane lung (2) can be prevented from returning to the inlet end of the centrifugal pump (1) after the first vascular clamp (81) is clamped;

the second vascular clamp (82) is arranged on a second drainage tube (4) from the outlet end of the centrifugal pump (1) to the inlet end of the membrane lung (2) and is used for clamping a pipeline at the position when the ECMO machine is started up/shut down;

the third vascular clamp (83) is arranged on the ECMO pre-flushing pipe II (61) at the lower part of the reflux bag (6);

the fourth vascular clamp (84) is arranged on the first ECMO pre-flushing pipe (51) at the lower part of the pre-flushing bag (5), and the third vascular clamp (83) and the fourth vascular clamp (84) can close/open the flow of the pre-flushing liquid.

2. The ECMO pre-fill system according to claim 1, wherein the filter head (71) is located in a passage (7) communicating the return bag (6) and the pre-fill bag (5), and is fixedly connected to the one-way check valve (72).

3. The ECMO pre-fill system according to claim 2, wherein the filter head (71) is a hollow structure having an outlet end (711), an inlet end (712), and sidewalls (713) extending therebetween, and the sidewalls (713) of the filter head (71) are provided with a plurality of filter holes (714) extending therethrough in a direction of the sidewalls.

4. The ECMO pre-fill system as claimed in claim 3, wherein the diameter of the filtering hole (714) is 0.3-0.6 mm, and the length of the filtering hole (714) is 5-8 mm.

5. An ECMO pre-fill system according to any one of claims 1-4, wherein the filter head (71) is a hollow structure of boss type, the left end of the filter head (71) is connected to the inlet port (712) of the return bag (6), the right end is connected to the outlet port (711) of the return bag (72), and the diameter of the opening of the inlet port (712) at the left end of the filter head (71) is larger than the diameter of the opening of the outlet port (711) at the right end.

6. An ECMO pre-fill device in accordance with any one of claims 1-4, wherein the one-way check valve (72) is a one-way valve body, and pre-fill fluid entering the filter head (71) can only enter the pre-fill bag (5) through the one-way check valve (72), and pre-fill fluid entering the pre-fill bag (5) cannot directly enter the return bag (6) through the one-way check valve (72).

7. An ECMO hermetic pre-filling device according to any one of claims 1-4, wherein the first port (31) and the second port (32) are provided with female screws, and one end of the second ECMO pre-filling pipe (61) at the lower part of the return bag (6) and one end of the first ECMO pre-filling pipe (51) at the lower part of the pre-filling bag (5) are both provided with male screws;

the external thread of an ECMO pre-washing pipe I (51) at the lower part of the pre-washing bag (5) can be connected with the internal thread of the connector I (31), and the external thread of an ECMO pre-washing pipe II (61) at the lower part of the backflow bag (6) can be connected with the internal thread of the connector II (32).

8. An ECMO hermetic pre-filling device according to any one of claims 1-4, wherein the other end of the ECMO pre-filling tube II (61) at the lower part of the pre-filling bag (6) and the other end of the ECMO pre-filling tube I (51) at the lower part of the pre-filling bag (5) are provided with piercing needles for connecting the pre-filling bag (5) and the pre-filling bag (6).

9. An ECMO pre-fill system according to any one of claims 1-4, wherein the height of the passageway (7) connecting the pre-fill bag (5) and the return bag (6), the filter head (71) and the one-way check valve (72) are located on the same horizontal plane and located at 1/3-1/4 of the pre-fill bag (5) height.

10. The ECMO pre-fill system according to claim 8, wherein the pre-fill bag (5) and the return bag (6) have the same size of bottom surface, and the volume of the return bag (6) is not more than half of the volume of the pre-fill bag (5).

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