CN210945443U

CN210945443U - Continuous production device for latex particles

Info

Publication number: CN210945443U
Application number: CN201922074623.4U
Authority: CN
Inventors: 蒋理国; 徐长银; 顾悦
Original assignee: Dialab Zhangjiagang Biotechnology Co ltd
Current assignee: Dialab Zhangjiagang Biotechnology Co ltd
Priority date: 2019-11-27
Filing date: 2019-11-27
Publication date: 2020-07-07
Anticipated expiration: 2029-11-27

Abstract

The utility model relates to a continuous production device of latex granule, apparatus for producing includes the mixing board, forms mixing intralamellar part runner, seting up a plurality of entries on the mixing board and seting up export on the mixing board is a plurality of the entry the export respectively with the both ends intercommunication of runner, the reaction raw materials of latex granule are from a plurality of respectively the entry gets into the runner and be in carry out the reaction in the runner and generate the latex granule, contain the reaction feed liquid of latex granule is followed the export flows the mixing board. Utilize the utility model discloses the device to select appropriate technological parameter and condition, can realize the continuous production of latex granule, like the continuous production of polystyrene latex granule, and in latex granule preparation process, the device is airtight, throws the material contactless air, need not nitrogen protection. Compared with the traditional intermittent latex particle production, the continuous production of the latex particles can be realized, and the particle size is adjustable.

Description

Continuous production device for latex particles

Technical Field

The utility model relates to a production device, in particular to a continuous production device for latex particles.

Background

At present, the following methods are commonly used for preparing the high molecular polymer microspheres: emulsion polymerization, suspension polymerization, dispersion polymerization, and soap-free emulsion polymerization.

Wherein, the latex particles prepared by the soap-free emulsion polymerization technology have the following characteristics: 1. the emulsifier is not used in the preparation process, the complex emulsifier post-treatment process is omitted, the pollution of the prepared latex particles is small, and the biocompatibility is good; 2. the surface of the latex particles is clean, so that the adverse effect on the detection performance of the prepared biochemical reagent is avoided; 3. the prepared latex particles have good monodispersity and uniform size.

The nucleation mechanism of the soap-free emulsion polymerization includes homogeneous nucleation mechanism, mother particle condensation nucleation mechanism, oligomer micelle nucleation mechanism, etc. It is generally believed that the nucleation mechanism for monomers with lower water solubility, such as styrene, in soap-free emulsion systems is an oligomeric micellar nucleation mechanism. It was observed by means of an electron microscope or the like that a large amount of styrene oligomer was present in the initial stage of polymerization in a soap-free emulsion polymerization system of styrene/potassium persulfate/water, and this stage was defined as a nucleation stage. In the nucleation period, the number of the oligomer is gradually increased, and the concentration of the free radical active chain in the water phase is gradually reduced by continuously capturing the oligomer. As the high molecular weight polymer in the latex particles is formed, the surface charge density of the particles is greatly reduced, the stability of the particles is lowered, and thus the polymerization between the particles occurs, which is defined as a growth period. The finally obtained polystyrene particles have a particle size determined by various factors including the amount of styrene monomer, the amount of initiator, the reaction temperature, the ionic strength and the like.

Patent CN103275275A discloses a method for preparing functionalized monodisperse polystyrene hybrid colloid emulsion, which comprises polymerizing styrene monomer, emulsion stabilizer, initiator and other substances in nitrogen environment and high temperature environment of 98-100 ℃ for 2 hours, adding high activity polymer monomer and initiator, and continuing to react for more than 3 hours to obtain the product. The colloidal particles prepared by the method have adjustable particle size and good monodispersity.

Patent CN107216421A discloses a preparation method of monodisperse polystyrene microspheres. The method takes styrene as a main monomer and prepares the polystyrene microsphere through soap-free emulsion polymerization. The patent is characterized in that no stabilizer is needed to be used, and no stabilizer in the product needs to be removed additionally.

However, the above-mentioned preparation methods require production in a nitrogen atmosphere and cannot be continuously produced, and in order to obtain polystyrene latexes of different particle sizes, it is necessary to start the production again by separately starting a furnace. Furthermore, the existing equipment for preparing polystyrene latex particles is usually a reaction kettle for batch polymerization.

Disclosure of Invention

The utility model aims to solve the technical problem that a continuous production device of latex particle is provided.

For solving the technical problem, the utility model discloses a following technical scheme:

the utility model provides a continuous production device of latex granule, apparatus for producing includes the mixing board, forms mixing inboard runner, seting up a plurality of entries on the mixing board and seting up export on the mixing board is a plurality of the entry the export respectively with the both ends intercommunication of runner, the reaction raw materials of latex granule are from a plurality of the entry gets into the runner and the runner is interior to mix and carry out polymerization and generate the latex granule, contains the reaction feed liquid of latex granule is followed the export flows mixing board.

According to some implementation aspects of the utility model, the runner is including forming mixing intralamellar part's public runner, formation are in mixing intralamellar part's a plurality of entry runners and formation are in mixing intralamellar part's export runner, it is a plurality of entry runner is with a plurality of the entry one-to-one sets up, and is a plurality of entry runner's one end corresponds respectively with a plurality of the entry intercommunication is a plurality of entry runner's the other end respectively with public runner's one end intercommunication, export runner's both ends respectively with public runner's the other end export intercommunication.

Preferably, the common flow channel is zigzag-shaped.

Preferably, the common flow channel is a rectangular flow channel with a cross section size of 200-1000 × 200-1000 microns, a rectangular flow channel with a cross section size of 100-500 × 200-1000 microns, a circular flow channel with an inner diameter of 200-1000 microns or a semicircular flow channel with a radius of 100-500 microns.

Preferably, the inlet flow channel and the outlet flow channel are respectively a rectangular flow channel with a cross section size of 200-1000 × 200-1000 microns, a rectangular flow channel with a cross section size of 100-500 × 200-1000 microns, a circular flow channel with an inner diameter of 200-1000 microns or a semicircular flow channel with a radius of 100-500 microns.

According to some implementation aspects of the utility model, the material of mixing board is glass.

According to some aspects of the present disclosure, the inlet is provided in 3.

According to some embodiments of the invention, the latex particles are polystyrene latex particles. In other embodiments, the latex particles may also be other latex particles than polystyrene latex particles.

According to some implementation aspects of the utility model, the apparatus for producing still includes a plurality of syringe pumps that contain the syringe that are used for depositing reaction raw materials, is used for depositing the product collection container of reaction feed liquid, connect respectively a plurality of syringe and a plurality of first connecting pipe between the entry and connection export and the second connecting pipe between the product collection container.

The first connecting pipe and the second connecting pipe are respectively Teflon pipes.

Because of the application of the technical scheme, compared with the prior art, the utility model has the following advantages:

utilize the utility model discloses the device to select appropriate technological parameter and condition, can realize the continuous production of latex granule, like the continuous production of polystyrene latex granule, and in latex granule preparation process, the device is airtight, throws the material contactless air, need not nitrogen protection. Compared with the traditional intermittent latex particle production, the continuous production of the latex particles can be realized, and the particle size is adjustable.

Drawings

Fig. 1 is a schematic structural diagram of a production apparatus according to an embodiment of the present invention;

FIG. 2 is a schematic diagram of the mixing plate of the apparatus of FIG. 1 (showing internal flow channels);

FIG. 3 is an enlarged view of the point A in FIG. 2;

the numbers in the above figures represent the names:

1. uniformly mixing the plates; 2. a common flow path; 3. an inlet; 4. an outlet; 5. an inlet flow passage; 6. an outlet flow passage; 7. an injector; 8. a first connecting pipe; 9. a product collection container; 10. a second connecting pipe.

FIG. 4 is a schematic view showing the particle size distribution of the latex particles of examples 1 to 3.

Detailed Description

The invention is further described below with reference to the drawings in the specification:

the continuous production device of latex granule as shown in fig. 1-3, including mixing board 1, form at the inside runner of mixing board 1, set up a plurality of entrances 3 on mixing board 1 and set up export 4 on mixing board 1, a plurality of entrances 3, export 4 communicate with the both ends of runner respectively, the reaction raw materials of latex granule gets into the runner and mixes and react in the runner and produce the latex granule from a plurality of entrances respectively, the reaction feed liquid that contains the latex granule flows out mixing board 1 from the export.

Referring to fig. 2, the flow channel includes a common flow channel 2 formed inside the blending plate 1, a plurality of inlet flow channels 5 formed inside the blending plate 1, and an outlet flow channel 6 formed inside the blending plate 1, the plurality of inlet flow channels 5 are arranged in one-to-one correspondence with the plurality of inlets 3, one ends of the plurality of inlet flow channels 5 are respectively communicated with the plurality of inlets 3, the other ends of the plurality of inlet flow channels 5 are respectively communicated with one end of the common flow channel 2, and two ends of the outlet flow channel 6 are respectively communicated with the other end of the common flow channel 2 and the outlet 4.

The common flow channel 2 is in a zigzag shape, and the common flow channel 2 is a rectangular flow channel with the cross section size of 200-1000 × 200-1000 microns, a rectangular flow channel with the cross section size of 100-500 × 200-1000 microns, a circular flow channel with the inner diameter of 200-1000 microns or a semicircular flow channel with the radius of 100-500 microns.

The inlet flow channel 5 and the outlet flow channel 6 are respectively a rectangular flow channel with a cross section size of 200-1000 × 200-1000 microns, a rectangular flow channel with a cross section size of 100-500 × 200-1000 microns, a circular flow channel with an inner diameter of 200-1000 microns or a semicircular flow channel with a radius of 100-500 microns.

In this example, the kneading plate 1 is made of glass. 3 inlets 3 are provided, and 3 inlet flow passages 5 are correspondingly provided.

The production device also comprises a plurality of injection pumps containing injectors 7 for storing reaction raw materials, a product collecting container 9 for storing reaction feed liquid, first connecting pipes 8 respectively connected between the injectors 7 and the inlets 3, and second connecting pipes 10 connected between the outlets 4 and the product collecting container 9, wherein the first connecting pipes 8 and the second connecting pipes 10 are Teflon pipes respectively.

The mixer plate 1 of the present example can be prepared by the following method:

A. selecting 2 glass materials;

B. by using CO₂Etching the glass material 1 by a laser, and etching 3 inlet grooves, 1 outlet groove and 1 zigzag groove on the surface of the glass material 1 by controlling the power and the path of a laser beam, wherein the etching depth is 500 microns, and the etching width is 1000 microns;

C. by using CO₂Etching the glass material 2 by a laser, and etching 4 through holes on the surface of the glass material 2 by controlling the power and the path of a laser beam, wherein 3 through holes correspond to the end part of an inlet groove of the glass material 1, and 1 through hole corresponds to the end part of an outlet groove of the glass material 1;

D. aligning the glass material 1 and the glass material 2, carrying out high-temperature thermal bonding, forming an inlet flow channel at the position of an inlet groove, forming an outlet flow channel at the position of an outlet groove and forming a common flow channel by using a zigzag groove after bonding, wherein the structure is shown in fig. 2.

Adopt the utility model discloses a several embodiments of apparatus for producing polystyrene latex granule in succession are as follows:

application example 1

In this example, the continuous production of polystyrene latex particles is taken as an example, and the adopted reaction raw materials are a styrene monomer reagent with a concentration of 0.9mol/L, a sodium chloride solution with a concentration of 10mmol/L and a potassium persulfate solution with a concentration of 10 mmol/L.

The method comprises the following specific steps:

1) placing the whole production device in a temperature control box, and controlling the temperature of the temperature control box to be 80 ℃;

2) respectively installing an injector filled with a styrene monomer reagent (with the concentration of 0.9mol/L), an injector loaded with a stabilizer sodium chloride solution (with the concentration of 10mmol/L) and an injector loaded with an initiator potassium persulfate solution (with the concentration of 10mmol/L) on three injection pumps, and respectively connecting the three injectors and 3 inlets through Teflon pipes;

3) connecting the outlet of the mixing plate with a product collecting container by using a Teflon pipe;

4) setting parameters of each injection pump, starting the injection pump, continuously pumping the styrene monomer, the sodium chloride solution and the potassium persulfate solution into the mixing plate at the flow rates of 10uL/min, 50uL/min and 50uL/min respectively, and after the reaction is stable, continuously feeding the reaction liquid into a product collecting container through a Teflon pipe.

Application example 2

This example provides a continuous process for the production of polystyrene latex particles, differing from example 1 in that: and (3) continuously pumping the styrene monomer, the sodium chloride solution and the potassium persulfate solution into the uniformly mixing plate at the flow rates of 20uL/min, 50uL/min and 50uL/min respectively, and continuously feeding the reaction liquid into a product collecting container through a Teflon pipe after the reaction is stable.

Application example 3

This example provides a continuous process for the production of polystyrene latex particles, differing from example 1 in that: and (3) continuously pumping the styrene monomer, the sodium chloride solution and the potassium persulfate solution into the uniformly mixing plate at the flow rates of 50uL/min, 50uL/min and 50uL/min respectively, and continuously feeding the reaction liquid into a product collecting container through a Teflon pipe after the reaction is stable.

Analysis of results

The reaction liquid containing polystyrene latex particles prepared in application examples 1 to 3 was analyzed by a nanoparticle particle size analyzer, and the analysis results are shown in fig. 4.

Therefore, polystyrene latex particles with different particle sizes can be continuously prepared by adjusting the injection flow rates of the styrene monomer, the sodium chloride solution and the potassium persulfate solution.

The above embodiments are only for illustrating the technical concept and features of the present invention, and the purpose thereof is to enable those skilled in the art to understand the contents of the present invention and to implement the present invention, so as not to limit the protection scope of the present invention, and all equivalent changes or modifications made according to the spirit of the present invention should be covered by the protection scope of the present invention.

Claims

1. A continuous production device of latex particles is characterized in that: the apparatus for producing includes the mixing board, forms mixing inboard inside runner, set up a plurality of entries on the mixing board and set up export on the mixing board is a plurality of the entry the export respectively with the both ends intercommunication of runner, the reaction raw materials of latex granule are from a plurality of the entry gets into the runner and mix in the runner and carry out polymerization and generate the latex granule, contain the reaction feed liquid of latex granule is followed the export flows the mixing board.

2. The continuous production apparatus of latex particles according to claim 1, characterized in that: the runner is including forming mixing intralamellar part's public runner, formation are in mixing intralamellar part's a plurality of entry runners and formation are in mixing intralamellar part's export runner, it is a plurality of entry runner is with a plurality of the entry one-to-one sets up, and is a plurality of the one end of entry runner corresponds respectively with a plurality of the entry intercommunication is a plurality of the other end of entry runner respectively with the one end intercommunication of public runner, the both ends of export runner respectively with the other end of public runner the export intercommunication.

3. The continuous production apparatus of latex particles according to claim 2, characterized in that: the common flow channel is in a zigzag shape.

4. The continuous production apparatus for latex particles according to claim 2, wherein said common flow path is a rectangular flow path having a cross-sectional dimension of 200 to 1000 × 200 to 1000. mu.m, a rectangular flow path having a cross-sectional dimension of 100 to 500 × 200 to 1000. mu.m, a circular flow path having an inner diameter of 200 to 1000. mu.m, or a semicircular flow path having a radius of 100 to 500. mu.m.

5. The continuous production apparatus for latex particles according to claim 2, wherein said inlet channel and said outlet channel are a rectangular channel having a cross-sectional dimension of 200 to 1000 × 200 to 1000 μm, a rectangular channel having a cross-sectional dimension of 100 to 500 × 200 to 1000 μm, a circular channel having an inner diameter of 200 to 1000 μm, or a semicircular channel having a radius of 100 to 500 μm, respectively.

6. The continuous production apparatus of latex particles according to claim 1, characterized in that: the material of mixing board is glass.

7. The continuous production apparatus of latex particles according to claim 1, characterized in that: the number of the inlets is 3.

8. The continuous production apparatus of latex particles according to claim 1, characterized in that: the latex particles are polystyrene latex particles.

9. The continuous production apparatus for latex particles according to any one of claims 1 to 8, wherein: the production device also comprises a plurality of injection pumps containing injectors for storing the reaction raw materials, a product collecting container for storing the reaction feed liquid, a first connecting pipe and a second connecting pipe, wherein the first connecting pipe is respectively connected between the injectors and the inlets, and the second connecting pipe is connected between the outlet and the product collecting container.

10. The continuous production apparatus of latex particles according to claim 9, characterized in that: the first connecting pipe and the second connecting pipe are respectively Teflon pipes.