CN210923225U - Dyeing device for chromosome aberration analysis - Google Patents

Dyeing device for chromosome aberration analysis Download PDF

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Publication number
CN210923225U
CN210923225U CN201921144561.3U CN201921144561U CN210923225U CN 210923225 U CN210923225 U CN 210923225U CN 201921144561 U CN201921144561 U CN 201921144561U CN 210923225 U CN210923225 U CN 210923225U
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slide
dyeing
slide frame
groove
staining
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Chinese (zh)
Inventor
白佳玫
张忠新
张睿凤
杨彪
邢利虹
任越
党旭红
柴栋良
段志凯
左雅慧
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China Institute for Radiation Protection
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China Institute for Radiation Protection
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Abstract

The utility model relates to a dyeing device for chromosome aberration analysis, which comprises a cuboid box-shaped dyeing main board, at least two slide racks and at least one drain hole with an opening and closing cover; the slide frame is the cuboid and evenly puts along dyeing mainboard long limit, the slide frame includes a first slide frame and the second slide frame that remains to be equipped with the draw-in groove, second slide frame draw-in groove opening is towards first slide frame, the draw-in groove both ends are equipped with the baffle. The utility model provides a dyeing apparatus simple structure, the practicality is strong, improvement user's that can be great work efficiency.

Description

Dyeing device for chromosome aberration analysis
Technical Field
The utility model belongs to the technical field of the radiation medicine, especially, a dyeing apparatus for chromosome aberration analysis.
Background
Chromosome aberration is one of the sensitive indicators of ionizing radiation effects and has been considered as the gold standard for biological dose estimation. The technical code of professional health supervision of radiological workers (GBZ235-2011) states that: chromosome aberration analysis is a necessary item for radiological worker occupational health examinations. Chromosomal aberrations are numerical and structural abnormalities in which normal chromosomes are exposed to physical (e.g., ionizing radiation), chemical, or biological effects. The chromosome aberration analysis comprises the processes of peripheral venous blood collection, trace whole blood culture, chromosome specimen preparation, slide reading and the like. The preparation of the chromosome specimen comprises the processes of hypotonic, pre-fixing, flaking, dyeing and the like.
The traditional slide dyeing is carried out on a glass plate, one end of a slide to be dyed is lifted by a plurality of waste slides, then Giemsa dyeing liquid is added, the dyeing liquid slowly flows into the bottom end of the slide to be dyed along one end of the slide, but because gaps exist among the waste slides, bubbles are easily generated in the dyeing liquid, the slide is not well colored, so that a reader can difficultly read the slide, in addition, because the slides are not fixed, the slide running and the risk of falling and breaking are easy to occur, in a washing link, a laboratory generally uses tweezers to clamp each slide for washing, the time consumption is long, the risk of falling is high, in addition, a 45cm × 30cm glass plate is heavy, the dyeing liquid easily flows out, and laboratories and operators are polluted.
Therefore, it is necessary to design a staining apparatus for analyzing chromosome aberrations.
SUMMERY OF THE UTILITY MODEL
The utility model aims at solving the defects in the prior art, and providing a dyeing device for chromosome aberration analysis.
In order to realize the purpose, the utility model discloses a technical scheme is: a dyeing device for chromosome aberration analysis comprises a cuboid box-shaped dyeing main board, at least two slide racks and at least one drain hole with an opening and closing cover;
the slide frame is the cuboid and evenly puts along dyeing mainboard long limit, the slide frame includes a first slide frame and the second slide frame that remains to be equipped with the draw-in groove, second slide frame draw-in groove opening is towards first slide frame, the draw-in groove both ends are equipped with the baffle.
Furthermore, the dyeing main board is made of acrylic materials.
Furthermore, the glass frame is made of acrylic materials.
Further, the inside of the dyed main board is 450mm × 300mm, 300mm × 3mm in size.
Furthermore, the number of the slide racks is 4, the slide racks comprise 3 second slide racks, each slide rack is pasted on the dyeing main board at a distance of 70mm,
the second slide rack size was 392mm × 10mm × 3mm, including a baffle plate having a thickness of 1 mm.
Further, the size of the clamping groove is 390mm × 2mm × 2mm, and the height of the clamping groove from the bottom to 1mm is used for placing a slide.
Further, the diameter of the drain hole is 15 mm.
Further, the dyeing device also comprises handles which are fixed on two sides of the dyeing main board in pairs.
The utility model has the advantages that: the utility model has simple structure, strong practicability, and concretely, the dyeing main board is made of acrylic material, is light and is not easy to break; the slide rack is fixed in position and provided with the clamping grooves, so that the to-be-dyed sheets are tightly and firmly arranged, the possibility of generating bubbles is reduced, and the risks of running and breaking of the to-be-dyed sheets are avoided; the bottom of the dyeing main board is provided with a drain hole of the opening and closing cover, and the whole design adopts a cuboid box-shaped design, so that dye liquor can be prevented from flowing outwards, the pollution to a laboratory and operators is reduced, most importantly, in a washing link, the opening and closing cover is opened, and the film is directly washed under tap water, so that the operation link is reduced, the efficiency is improved, and the risk of slide falling is reduced; the handles on the two sides of the main board are convenient to operate, and meanwhile, the risk of dye liquor pollution is reduced; the bottom of the next slide rack is used for fixing the slide, so that the space can be utilized to the maximum extent, more slides can be dyed on the premise of achieving the purpose of fixing the slide, and the working efficiency is greatly improved.
Drawings
FIG. 1 is a schematic structural diagram of an embodiment of a staining apparatus for analyzing chromosome aberrations according to the present invention;
FIG. 2 is a schematic view of the dyeing process of the dyeing apparatus for analyzing chromosome aberration according to the present invention.
In the figure: 1-dyeing a main board; 2-a slide rack; 3-a drain hole; 4-a handle; 5-a slide with a chromosome specimen adhered thereon; 21-card slot.
Detailed Description
In order to make the technical problem solved by the present invention, the technical solution adopted by the present invention and the technical effect achieved by the present invention clearer, the following will combine the accompanying drawings to describe the technical solution of the embodiments of the present invention in further detail. It is to be understood that the embodiments described are only some embodiments of the invention, and not all embodiments. All other embodiments obtained by a person skilled in the art based on the embodiments of the present invention without any creative work belong to the protection scope of the present invention.
Referring to fig. 1, fig. 1 is a schematic structural diagram of an embodiment of a staining apparatus for analyzing chromosome aberration according to the present invention. A staining apparatus for chromosome aberration analysis,
a dyeing device for chromosome aberration analysis comprises a cuboid box-shaped dyeing main board 1, at least two slide racks 2 and at least one drain hole 3 with an opening and closing cover;
slide frame 2 evenly puts along dyeing mainboard 1 long limit for the cuboid, slide frame 2 includes a first slide frame and the second slide frame that remains to be equipped with draw-in groove 21, second slide frame draw-in groove 21 opening is towards first slide frame, draw-in groove 21 both ends are equipped with the baffle.
The dyeing mainboard 1 is made of acrylic materials.
The slide frame 2 is made of acrylic material.
In a specific embodiment, the inside of the main staining plate 1 is × 300mm and × 3mm in size of 450mm and the inside of the main staining plate 1 is 2mm in thickness of acrylic plate, so that the main staining plate 1 is a cuboid box-shaped container with the outside size of 454mm, × 304mm, × 5mm (length, × mm, width, × mm) and the slide racks 2 are 4 in number and comprise 3 second slide racks, each slide rack 2 is adhered to the main staining plate 1 at a distance of 70mm, the size of the second slide rack is 392mm, × 10mm, × 3mm and comprises baffles with the thickness of 1mm at two ends, and each second slide rack can be used for placing 15 slides in parallel, wherein the thickness of each second slide rack is 70mm, × 26 mm.
Preferably, the size of the clamping groove 21 is 390mm × 2mm × 2mm, the height of the opening of the clamping groove 21 in the second slide holder 2, which is 1mm from the bottom, is used for holding a slide, and baffles with the thickness of 1mm are arranged on two sides of the clamping groove 21 and used for fixing the slide, the slide is fixed to reduce the gap between the slides, so that the slide can better utilize the siphon effect to enable the dye solution to be adsorbed onto the slide.
The diameter 3 of the drain hole is 15mm, and an opening and closing cover is arranged.
The dyeing device also comprises handles 4, and the handles 4 are fixed on two sides of the dyeing main board 1 in pairs.
Referring to fig. 2, fig. 2 is a schematic view of a staining process of a staining apparatus for analyzing chromosome aberrations according to the present invention. Use the utility model discloses during the dyeing apparatus, including following step:
(1) the main board is cleaned by alcohol cotton. If the cleaning is not clean, the giemsa dyeing liquid is easy to flow unsmoothly, and bubbles are generated.
(2) And reversely buckling the slide glass loaded with the chromosome specimen on a slide glass rack with a clamping groove, and tightly connecting the slide glass with the slide glass.
(3) The drain hole at the bottom is in a closed state, and Giemsa dye solution is absorbed by a dropper to be slowly dripped from the bottom of the glass slide until the whole glass slide is fully stained with the Giemsa dye solution.
(4) And after dyeing for 8-10 minutes, opening the drain hole, placing under a tap water pipe for washing, and naturally drying.
Compared with the prior art, the utility model has the advantages of simple structure, strong practicability, and concretely, the dyeing main board is made of acrylic material, is light and is not easy to break; the slide rack is fixed in position and provided with the clamping grooves, so that the to-be-dyed sheets are tightly and firmly arranged, the possibility of generating bubbles is reduced, and the risks of running and breaking of the to-be-dyed sheets are avoided; the bottom of the dyeing main board is provided with a drain hole of the opening and closing cover, and the whole design adopts a cuboid box-shaped design, so that dye liquor can be prevented from flowing outwards, the pollution to a laboratory and operators is reduced, most importantly, in a washing link, the opening and closing cover is opened, and the film is directly washed under tap water, so that the operation link is reduced, the efficiency is improved, and the risk of slide falling is reduced; the handles on the two sides of the main board are convenient to operate, and meanwhile, the risk of dye liquor pollution is reduced; the bottom of the next slide rack is used for fixing the slide, so that the space can be utilized to the maximum extent, more slides can be dyed on the premise of achieving the purpose of fixing the slide, and the working efficiency is greatly improved.
It will be understood by those skilled in the art that the device of the present invention is not limited to the embodiments described in the detailed description, and the above detailed description is for the purpose of explanation and not limitation of the invention. The technical solution according to the present invention is used by those skilled in the art to derive other embodiments, which also belong to the technical innovation scope of the present invention, and the protection scope of the present invention is defined by the claims and their equivalents.

Claims (8)

1. A dyeing device for chromosome aberration analysis is characterized by comprising a cuboid box-shaped dyeing main board, at least two slide racks and at least one drain hole with an opening and closing cover;
the slide frame is the cuboid and evenly puts along dyeing mainboard long limit, the slide frame includes a first slide frame and the second slide frame that remains to be equipped with the draw-in groove, second slide frame draw-in groove opening is towards first slide frame, the draw-in groove both ends are equipped with the baffle.
2. The staining apparatus for analyzing chromosomal aberration of claim 1, wherein the staining main plate is made of acrylic material.
3. The staining apparatus of claim 1 wherein the slide holder is acrylic.
4. The staining apparatus for analyzing chromosome aberrations of claim 1, wherein the inside of the stained main plate is 450mm × 300mm × 3mm in size.
5. The staining apparatus for chromosomal aberration analysis according to claim 4, wherein the slide rack has 4, including 3 second slide racks, each slide rack being attached to the staining main plate at a distance of 70 mm;
the second slide rack size was 392mm × 10mm × 3mm, including a baffle plate having a thickness of 1 mm.
6. The staining apparatus for analyzing chromosomal aberration according to claim 5, wherein the size of the groove is 390mm × 2mm × 2mm, and the groove is 1mm high from the bottom for mounting a slide.
7. The staining apparatus for analyzing chromosomal aberration according to claim 1, wherein the drainage hole has a diameter of 15 mm.
8. The staining apparatus for analyzing chromosomal aberration according to claim 1, further comprising handles attached to both sides of the main staining plate in pairs.
CN201921144561.3U 2019-07-19 2019-07-19 Dyeing device for chromosome aberration analysis Active CN210923225U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201921144561.3U CN210923225U (en) 2019-07-19 2019-07-19 Dyeing device for chromosome aberration analysis

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201921144561.3U CN210923225U (en) 2019-07-19 2019-07-19 Dyeing device for chromosome aberration analysis

Publications (1)

Publication Number Publication Date
CN210923225U true CN210923225U (en) 2020-07-03

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
CN201921144561.3U Active CN210923225U (en) 2019-07-19 2019-07-19 Dyeing device for chromosome aberration analysis

Country Status (1)

Country Link
CN (1) CN210923225U (en)

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