CN210595867U

CN210595867U - Heme concentrating device

Info

Publication number: CN210595867U
Application number: CN201921281186.7U
Authority: CN
Inventors: 莫宏春
Original assignee: Gansu Yangtaihe Biotechnology Ltd
Current assignee: Gansu Yangtaihe Biotechnology Ltd
Priority date: 2019-08-08
Filing date: 2019-08-08
Publication date: 2020-05-22
Anticipated expiration: 2029-08-08

Abstract

The utility model discloses a heme enrichment facility belongs to biological purification technical field to solve the problem that acetone is collected inadequately in the heme concentration, the comdenstion water quantity is big. The constant-temperature water bath device comprises a constant-temperature water bath box, a condenser pipe and an acetone collecting bottle, wherein the air outlet end of the constant-temperature water bath box is connected with a heat exchange pipe in the condenser pipe through a gas conveying pipe, and the tail end of the heat exchange pipe is connected with the acetone collecting bottle; the bottom end of a cooling cylinder body of the condensing pipe is connected with a water supply tank through a water inlet pipe, a cooling water pump is arranged on the water inlet pipe, the top end of the cooling cylinder body is connected with a water return tank through a water return pipe, the water return tank is positioned above the water supply tank, the water return tank is connected with the water supply tank through a self-flowing pipe, and the self-flowing pipe is provided with a self-flowing valve; the constant temperature water bath box is provided with a sealing mechanism and a vacuum pump, and the sealing mechanism comprises a pot cover positioned on the upper surface of the constant temperature water bath box and a fixing mechanism used for fixing the pot cover. The utility model collects the acetone; the cooling water also circulates in the water supply tank and the water return tank, so that energy is saved, consumption is reduced, cost is greatly saved, and economical efficiency is improved.

Description

Heme concentrating device

Technical Field

The utility model belongs to the technical field of biological purification, concretely relates to heme enrichment facility.

Background

The application of the pyruvate method for extracting the heme in the biological purification technology is wide, the heme needs to be dissolved in acetone in the prior process, and the acetone needs to be separated during purification, so that the purification effect is achieved.

In the prior art, acetone is volatilized by heating heme during purification, on one hand, the acetone cannot be collected after volatilization, so that waste is caused, and on the other hand, the acetone is randomly discharged to pollute the environment; the acetone has a high boiling point at normal pressure, needs higher heating, has large energy consumption on one hand, and has unknown influence on biochemical properties of raw materials due to high temperature on the other hand; and the separation under normal pressure consumes a large amount of cooling water during the condensation and collection of acetone due to the high temperature, so that the waste is serious. Based on the above factors, one skilled in the art provides a hemoglobin concentration device to solve the above problems.

SUMMERY OF THE UTILITY MODEL

An object of the utility model is to provide a heme enrichment facility to solve the problem that acetone is collected inadequately, the comdenstion water quantity is big in the heme is concentrated.

In order to solve the above problems, the utility model discloses technical scheme does:

a heme concentration device comprises a constant-temperature water bath tank, a condenser pipe and an acetone collection bottle, wherein the gas outlet end of the constant-temperature water bath tank is connected with a heat exchange pipe in the condenser pipe through a gas pipe, the gas pipe is a component made of PPr material, a valve is arranged in the middle section of the gas pipe, the PPr material has a heat insulation effect, the phenomenon that volatile gas is cooled, liquefied and reflows to the constant-temperature water bath tank again when the volatile gas is transmitted at low ambient temperature can be avoided, and the tail end of the heat exchange pipe is connected with the acetone collection bottle; the bottom end of a cooling cylinder body of the condensing pipe is connected with a water supply tank through a water inlet pipe, a cooling water pump is arranged on the water inlet pipe, the top end of the cooling cylinder body is connected with a water return tank through a water return pipe, the water return tank is positioned above the water supply tank, the water return tank is connected with the water supply tank through a self-flowing pipe, and the self-flowing pipe is provided with a self-flowing valve; the constant temperature water bath box is provided with a sealing mechanism and a vacuum pump, and the sealing mechanism comprises a pot cover positioned on the upper surface of the constant temperature water bath box and a fixing mechanism used for fixing the pot cover.

Further, fixed establishment includes interconnect's pillar and backup pad, and the pillar is three at least, and evenly establishes around the pot lid above the constant temperature water bath, and backup pad one end level is established at the pillar top, and the backup pad other end runs through and is provided with the screw rod, and the screw rod top is equipped with the knob, and the screw rod bottom is equipped with the preforming, and the preforming is pressed on the pot lid.

Furthermore, be equipped with the screw hole with screw rod looks adaptation in the backup pad, the preforming is made for the rubber material, and the pillar is connected through the upper surface rotation of pivot with the constant temperature water bath.

Furthermore, a supporting rod is fixed on one side of the constant-temperature water bath tank, a first fastening lantern ring and at least one group of second fastening lantern rings are fixedly sleeved outside the supporting rod, the first fastening lantern ring is horizontally connected with a first fixing ring, and an acetone collecting bottle is installed in the first fixing ring; the second fastening lantern ring is horizontally connected with a second fastening lantern ring, the cooling barrel is installed in the second fastening lantern ring, the second fastening lantern ring is connected with the second fastening lantern ring through a connecting rod, the supporting rod is a stainless steel component and is fixed on the side wall of the constant-temperature water bath box through an arc-shaped mounting seat and a matched bolt

Furthermore, the condensation pipe is provided with at least two stages from bottom to top, and the stage number is determined according to the length of the condensation pipe.

Furthermore, the heat exchange tube at the lowest stage is connected with the acetone collecting bottle through a liquid guide tube.

Furthermore, the constant temperature water bath box is connected with the vacuum pump through a vacuum tube.

Furthermore, a support frame is arranged above the water supply tank, and the water return tank is arranged on the support frame.

The utility model has the advantages as follows:

(1) the utility model utilizes the vacuum pump to cooperate with the sealing mechanism to vacuumize the constant-temperature water bath box, heats and concentrates the heme mixed liquid under the vacuum environment, reduces the boiling point of acetone, enters the heat exchange tube, condenses under the action of cooling water in the cooling cylinder, naturally falls to the acetone collecting bottle along the heat exchange tube to be collected, and the cooling water flows upwards under the action of the cooling water pump, enters the water return box along the water return pipe after heat exchange, automatically flows into the water supply box to be cooled after the operation is finished, and carries out the next cooling circulation; when the acetone is collected at low temperature, the circulating water is recycled, and the circulating water can automatically flow without additional power, so that the energy is saved and the environment is protected.

(2) The fixing mechanism can enable the pot cover to be precisely attached to the constant-temperature water bath box, and the problem that the vacuum difficulty is increased due to the gap between the pot cover and the constant-temperature water bath box is solved.

(3) The first fastening lantern ring and the second fastening lantern ring arranged on the supporting rod are convenient to move, the relative positions of the acetone collecting bottle, the cooling cylinder and other equipment are adjusted, and fragile glassware is convenient to replace.

(4) The condensation pipes are arranged in multiple stages, so that acetone can be conveniently and fully recovered; the support frame supports the return water tank, and cooling water flows automatically conveniently.

(5) The utility model has novel design and simple principle, collects acetone by the principles of volatilization, condensation and liquefaction, and is convenient for continuously dissolving the heme next time; the cooling water also circulates in the water supply tank and the water return tank, so that energy is saved, consumption is reduced, cost is greatly saved, and economical efficiency is improved.

Drawings

FIG. 1 is a schematic diagram of a hemoglobin concentration device;

FIG. 2 is an enlarged view of a portion A of the hemoglobin concentrating device of FIG. 1;

FIG. 3 is a schematic diagram of a fixing mechanism of the hemoglobin concentrating device.

The reference numbers are as follows: 1. a support frame; 2. a self-flow valve; 3. a water inlet pipe; 4. a first retaining ring; 5. a vacuum pump; 6. a vacuum tube; 7. a constant temperature water bath tank; 8. a first fastening collar; 9. an acetone collection bottle; 10. a gas delivery pipe; 11. a support bar; 12. a water return pipe; 13. cooling the cylinder; 14. a cooling water pump; 15. returning to a water tank; 16. a gravity flow pipe; 17. a water supply tank; 18. a second fastening collar; 19. a heat exchange pipe; 20. a fixing mechanism; 201. a pillar; 202. a support plate; 203. a knob; 204. a screw; 205. tabletting; 21. a second retaining ring; 22. a pot cover; 23. a catheter; 24. a connecting rod.

Detailed Description

The present invention will be described in further detail with reference to the accompanying drawings and specific embodiments.

The utility model provides a heme enrichment facility, including constant temperature water bath 7, the condenser pipe, acetone receiving flask 9, the end of giving vent to anger of constant temperature water bath 7 is connected with heat exchange tube 19 in the condenser pipe through gas-

supply pipe

10, 19 end-to-end connections of heat exchange tube have acetone receiving flask 9, it is specific, through catheter 23 connection between 19 of the heat exchange tube of lower one-level and the acetone receiving flask 9, the condenser pipe is from supreme at least setting up the two-stage down, inlet tube 3 connection feed water tank 17 is passed through to 13 bottoms of the cooling barrel of condenser pipe, be equipped with cooling water pump 14 on the inlet tube 3, return water tank 15 is connected through wet return 12 on 13 tops of cooling barrel, return water tank 15 is located feed water: a support frame 1 is arranged above the water supply tank 17, a water return tank 15 is arranged on the support frame 1, the water return tank 15 is connected with the water supply tank 17 through a gravity flow pipe 16, and a gravity flow valve 2 is arranged on the gravity flow pipe 16; the constant temperature water bath box 7 is provided with a sealing mechanism and a vacuum pump 5, the constant temperature water bath box 7 is connected with the vacuum pump 5 through a vacuum tube 6, and the sealing mechanism comprises a pot cover 22 positioned on the upper surface of the constant temperature water bath box 7 and a fixing mechanism 20 used for fixing the pot cover 22.

Specifically, the method comprises the following steps: the fixing mechanism 20 comprises a support column 201 and a support plate 202 which are connected with each other, the number of the support columns 201 is at least three, the support columns are evenly arranged around the pot cover 22 above the constant-temperature water bath tank 7, the support column 201 is rotatably connected with the upper surface of the constant-temperature water bath tank 7 through a rotating shaft, one end of the support plate 202 is vertically arranged above the support column 201, the other end of the support plate 202 penetrates through a screw 204, a threaded hole is formed in the connecting position of the support plate 202 and the screw 204, the threaded hole is matched with the screw 204, a knob 203 is arranged at the top end of the screw 204, a pressing sheet 205 is arranged at the bottom end of the screw 204, the.

A supporting rod 11 is fixed on one side of the constant temperature water bath tank 7, a first fastening lantern ring 8 and at least one group of second fastening lantern rings 18 are fixedly sleeved outside the supporting rod 11, the first fastening lantern ring 8 is horizontally connected with a first fixing ring 4, and an acetone collecting bottle 9 is installed in the first fixing ring 4; the second fastening collar 18 is horizontally connected with a second fixing ring 21, the cooling cylinder 13 is installed in the second fixing ring 21, and the second fixing ring 21 is connected with the second fastening collar 18 through a connecting rod 24.

The utility model discloses a working process is: firstly put into the constant temperature water bath 7 with the heme mixture dissolved by the last process, cover pot cover 22, rotate pillar 201 and make the one end that has preforming 205 be in the top of pot cover 22, after the position is confirmed, clockwise rotation knob 203 makes screw rod 204 rotate, make screw rod 204 can move down along the screw thread direction through the screw-on characteristic of screw thread, thereby make preforming 205 press in the edge of pot cover 22, be equipped with the rubber circle around pot cover 22, can make pot cover 22 and constant temperature water bath 7 laminate completely, reach sealed effect, provide convenience for vacuum pump 5 evacuation, avoid having the problem that the clearance leads to the evacuation failure between pot cover 22 and the constant temperature water bath 7, the boiling point of acetone can be reduced in the evacuation, make it produce volatilizing at very low temperature, purification efficiency is improved, time and energy consumption have been practiced thrift simultaneously.

Cooling water pump 14 takes the cooling water in the feed water tank 17 out, the cooling water after taking out gets into cooling barrel 13 along inlet tube 3, thereby change the inside temperature of cooling barrel 13, the volatile acetone of heating this moment gets into the inside snakelike heat exchange tube 19 of condenser pipe along gas-supply pipe 10, gaseous attached to the surface at heat exchange tube 19, through low-temperature liquefaction, acetone after the liquefaction gets into acetone receiving flask 9 through catheter 23 and collects, the acetone of collection and can be used for heme to dissolve once more, the cost is saved and waste, and the practicality has been increased.

The cooling water in the heat exchange tube 19 absorbs heat and then rises in temperature, the warmed cooling water is collected in the water return tank 15 through the water return tube 12 and is slowly cooled, the flow valve 2 is opened after the operation is finished, the collected cooling water flows into the water supply tank 17 through the flow valve 16, the cooling water cools in the water supply tank 17 after being cooled overnight during the operation on the next day, the flow valve 2 is closed, the cooling water in the water supply tank 17 can be cooled for the next round, the circulation is carried out, almost no additional cooling water is needed, the cost is greatly saved, and therefore the cooling water also adopts purified water, the whole cooling cylinder 13 can be kept clean and visualized all the time, and the operation is easier to observe.

Claims

1. A heme concentration device comprises a constant-temperature water bath tank (7), a condenser tube and an acetone collecting bottle (9), wherein the air outlet end of the constant-temperature water bath tank (7) is connected with a heat exchange tube (19) in the condenser tube through a gas conveying tube (10), and the tail end of the heat exchange tube (19) is connected with the acetone collecting bottle (9); the method is characterized in that: the bottom end of a cooling cylinder (13) of the condensation pipe is connected with a water supply tank (17) through a water inlet pipe (3), a cooling water pump (14) is arranged on the water inlet pipe (3), the top end of the cooling cylinder (13) is connected with a water return tank (15) through a water return pipe (12), the water return tank (15) is positioned above the water supply tank (17), the water return tank (15) is connected with the water supply tank (17) through a gravity flow pipe (16), and a gravity flow valve (2) is arranged on the gravity flow pipe (16); be equipped with closing mechanism and vacuum pump (5) on constant temperature water bath (7), closing mechanism is including pot cover (22) that are located constant temperature water bath (7) upper surface and fixed establishment (20) that are used for fixed pot cover (22).

2. A heme concentration device according to claim 1, wherein: the fixing mechanism (20) comprises a support column (201) and a support plate (202) which are connected with each other, the support column (201) is at least three, the periphery of a pot cover (22) above the constant-temperature water bath box (7) is uniformly arranged, one end of the support plate (202) is horizontally arranged at the top of the support column (201), a screw rod (204) is arranged at the other end of the support plate (202) in a penetrating mode, a knob (203) is arranged at the top end of the screw rod (204), a pressing sheet (205) is arranged at the bottom end of the screw rod (204), and the pressing sheet (205) is pressed on the pot cover (22).

3. A heme concentration device according to claim 2, wherein: the supporting plate (202) is provided with a threaded hole matched with the screw rod (204), the pressing sheet (205) is made of rubber, and the support column (201) is rotatably connected with the upper surface of the constant-temperature water bath box (7) through a rotating shaft.

4. A heme concentration device according to claim 3, wherein: a supporting rod (11) is fixed on one side of the constant-temperature water bath tank (7), a first fastening lantern ring (8) and at least one group of second fastening lantern rings (18) are fixedly sleeved outside the supporting rod (11), the first fastening lantern ring (8) is horizontally connected with a first fixing ring (4), and an acetone collecting bottle (9) is installed in the first fixing ring (4); the second fastening collar (18) is horizontally connected with a second fixing ring (21), the cooling cylinder body (13) is installed in the second fixing ring (21), and the second fixing ring (21) is connected with the second fastening collar (18) through a connecting rod (24).

5. A heme concentration device according to claim 4, wherein: the condensation pipe is at least provided with two stages from bottom to top.

6. A heme concentration device according to claim 5, wherein: the heat exchange tube (19) at the lowest stage is connected with the acetone collecting bottle (9) through a liquid guide tube (23).

7. A heme concentration device according to claim 6, wherein: the constant temperature water bath box (7) is connected with the vacuum pump (5) through a vacuum tube (6).

8. A heme concentration device according to claim 7, wherein: the support frame (1) is arranged above the water supply tank (17), and the water return tank (15) is arranged on the support frame (1).