CN210542888U - Retina prosthesis, implant device and flexible cable - Google Patents

Retina prosthesis, implant device and flexible cable Download PDF

Info

Publication number
CN210542888U
CN210542888U CN201920148824.1U CN201920148824U CN210542888U CN 210542888 U CN210542888 U CN 210542888U CN 201920148824 U CN201920148824 U CN 201920148824U CN 210542888 U CN210542888 U CN 210542888U
Authority
CN
China
Prior art keywords
retina
flexible cable
electrode
flexible
microelectrode
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CN201920148824.1U
Other languages
Chinese (zh)
Inventor
戴聿昌
庞长林
迪迪埃·萨根
王煜
张旭
曾维波
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Intellimicro Medical Co ltd
Original Assignee
Intellimicro Medical Co ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Intellimicro Medical Co ltd filed Critical Intellimicro Medical Co ltd
Priority to CN201920148824.1U priority Critical patent/CN210542888U/en
Application granted granted Critical
Publication of CN210542888U publication Critical patent/CN210542888U/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Landscapes

  • Prostheses (AREA)

Abstract

The utility model discloses a retina prosthesis, implantation device and flexible cable. Wherein, the flexible cable of retina prosthesis includes: the microelectrode, the microelectrode has two mounting holes, and including be located between two mounting holes the electrode zone and with the elasticity portion that the electrode zone links to each other, elasticity portion can at least be in the length direction of two mounting hole lines is out of shape tensile, elasticity portion has the hole of dodging that is suitable for corresponding retina nerve head, the electrode zone is equipped with the stimulation electrode that at least sixty arranged according to the law. According to the utility model discloses flexible cable can make microelectrode atress even and can laminate in order to obtain more effective stimulation effect in order to obtain better in the retina. The utility model also discloses a retina implant device and a retina prosthesis.

Description

Retina prosthesis, implant device and flexible cable
Technical Field
The utility model belongs to the technical field of ophthalmology nerve stimulator technique and specifically relates to a retina prosthesis's flexible cable, have its retina implant device and have this implant device's retina prosthesis.
Background
In the related art, when the implantation device of the retinal prosthesis is implanted, only one retinal nail is usually implanted, so that only one fixed stress point is arranged on the micro electrode in the planar structure, the other side opposite to the retinal nail is easy to tilt or uneven in stress, the distance between part of the stimulating electrode on the micro electrode and the surface of the retina is larger, and finally, a stimulating current with higher intensity is required to generate a better visual perception effect.
Since the number of the stimulating electrodes in the microelectrode is generally dozens, hundreds or even thousands, if a large proportion of the stimulating electrodes need large stimulating current, the total stimulating current is increased, which not only consumes electric energy and reduces the battery service time, but also causes nerve damage or convulsion in severe cases.
SUMMERY OF THE UTILITY MODEL
The utility model discloses aim at solving one of the technical problem that exists among the prior art at least. Therefore, the utility model provides a flexible cable of retina prosthesis.
The utility model also provides an implantation device of the retina that has above-mentioned flexible cable.
The utility model also provides a retina prosthesis with above-mentioned implantation device.
According to the utility model discloses a flexible cable of retina prosthesis of first aspect embodiment includes: the microelectrode, the microelectrode has two mounting holes, and including be located between two mounting holes the electrode zone and with the elasticity portion that the electrode zone links to each other, elasticity portion can at least be in the length direction of two mounting hole lines is out of shape tensile, elasticity portion has the hole of dodging that is suitable for corresponding retina nerve head, the electrode zone is equipped with the stimulation electrode that at least sixty arranged according to the law.
According to the utility model discloses flexible cable through setting up two mounting holes, is convenient for carry out two fixed points to the microelectrode when implanting the retina to make the atress of microelectrode even, the condition that also does not have the perk takes place, has guaranteed that the distance between stimulating electrode and the retina surface is even, thereby has avoided big stimulating current to lead to the injury to the human body. And the elastic part can ensure that the microelectrode can be better attached to the corresponding surface of the retina when being implanted into the retina.
According to some embodiments of the invention, the elastic portion comprises: one end of each flexible chain is connected with the electrode region, and the flexible chains can be deformed and stretched in the length direction; and the closed end, the closed end is connected the other end of two at least flexible chains, the closed end with inject between two at least flexible chains and be suitable for and correspond the hole of dodging of retina nerve dish to can avoid the interference of microelectrode to the retina nerve dish, and then guarantee accurate visual perception effect.
According to some embodiments of the present invention, the two mounting holes include a first mounting hole and a second mounting hole, the first mounting hole is located in one side of the closed end that is kept away from of the electrode region, the second mounting hole is located on the closed end.
According to some embodiments of the invention, the width of the flexible cable increases gradually in a direction towards the electrode region at a side remote from the closed end; the width of the closed end gradually decreases in a direction away from the electrode region. Therefore, the whole area of the microelectrode is reduced, the microelectrode is easy to implant into an eyeball, the damage to eyeball tissues caused by moving the microelectrode is reduced, and the cost can be reduced.
According to some embodiments of the invention, the flexible chain is configured as at least any one of the following structures: a helical spring structure, a wave shape, or a bellows structure.
According to some embodiments of the present invention, the end of the closed end further has a clamping end portion suitable for being clamped, so that the doctor can conveniently clamp the closed end during the operation, and the operation can be conveniently performed.
According to some embodiments of the invention, the elastic portion has a dimension in a width direction substantially equal to the electrode region, the width direction being perpendicular to the length direction of the flexible chain. Therefore, the outline of the microelectrode is smooth, and the microelectrode is easy to implant into the eyeball.
According to some embodiments of the invention, the plurality of stimulation electrodes are arranged in an array within the microelectrode, and the surface of the microelectrode in contact with the retina is configured to substantially match the curvature of the corresponding portion of the retina. Thus, the plurality of stimulating electrodes can be more effectively attached to the retina of the eyeball, and are in sufficient contact with the implanted portion of the retina, such as the foveal region, to generate more effective nerve stimulation.
According to a second aspect of the present invention, an implantation device for a retina comprises: the flexible cable according to the embodiment of the first aspect, further comprising an introduction portion and a connection portion, the connection portion being connected between the micro-electrode and the introduction portion; two fixing pieces for fixing the microelectrode of the flexible cable to the retina through the two mounting holes; electronics having a chip connected to the lead-in portion to drive the plurality of stimulation electrodes; a first wireless annunciator connected to the electronic device to receive image information obtained from the outside and to transmit the image information to the chip within the electronic device.
The microelectrode is fixed to the retina by the two fixing pieces penetrating through the two mounting holes respectively, the whole stress of the microelectrode is uniform, one end of the microelectrode cannot be tilted, the damage to the surface of the retina can be avoided, and the visual perception effect can be guaranteed. And the elastic part is arranged on the microelectrode of the flexible cable, so that the microelectrode can be better attached to the corresponding surface of the retina when being implanted.
A retinal prosthesis according to an embodiment of the third aspect of the present invention includes: an implantation device for a retina according to an embodiment of the second aspect of the present invention; an external device, the external device comprising: the camera shooting device comprises a camera shooting unit, a video processing unit and a second wireless annunciator, wherein the camera shooting unit is electrically connected with the video processing unit, the video processing unit is electrically connected with the second wireless annunciator, and the second wireless annunciator is electrically connected with the first wireless annunciator.
Additional aspects and advantages of the invention will be set forth in part in the description which follows and, in part, will be obvious from the description, or may be learned by practice of the invention.
Drawings
The above and/or additional aspects and advantages of the present invention will become apparent and readily appreciated from the following description of the embodiments, taken in conjunction with the accompanying drawings of which:
fig. 1 is a schematic diagram of a flexible cable according to an embodiment of the present invention;
FIG. 2 is an enlarged schematic view of a microelectrode portion of the flexible cable shown in FIG. 1;
FIG. 3 is a schematic perspective view of the flex cable shown in FIG. 1;
FIG. 4 is a schematic view of the flexible cable shown in FIG. 3 when implanted within an eyeball;
FIG. 5 is a cross-sectional view of the flexible cable of FIG. 4 implanted within an eye;
figure 6 is a schematic view of a fixation element in an implant device according to an embodiment of the present invention;
fig. 7 is a schematic view of a retinal prosthesis according to an embodiment of the present invention.
Reference numerals:
a flexible cable 100;
microelectrodes 110; a mounting hole 111; the first mounting hole 111 a; the second mounting hole 111 b;
electrode regions 112; an elastic portion 113; a flexible chain 1131; a closed end 1132; relief holes 1133; a clamping end 114;
an introduction portion 120; a connecting portion 130; a stimulation electrode 140;
an implant device 1000; a fixing member 200; an electronic device 300; a first wireless annunciator 400;
a retina 2000; a retinal nerve disk 2100; a central recessed region 2200; an eyeball 3000;
an external device 4000; an image pickup unit 4100; a video processing unit 4200; the second wireless signal 4300.
Detailed Description
Embodiments of the present invention are described in detail below, and the embodiments described with reference to the drawings are exemplary.
First, a flexible cable 100 of a retinal prosthesis according to an embodiment of the first aspect of the present invention is described below with reference to fig. 1 to 2.
As shown in fig. 1, the flexible cable according to the embodiment of the present invention includes: a micro-electrode 110, an introduction part 120, and a connection part 130. As shown in FIG. 2, the microelectrode 110 includes a flexible substrate that can function to support and protect the stimulation electrodes, and a plurality of stimulation electrodes 140 disposed thereon.
The micro-electrode 110 has two mounting holes 111 thereon, and specifically, the mounting holes 111 are provided on a flexible substrate. The two mounting holes 111 are adapted to correspond to both sides of the retinal nerve disk 2100 when the micro-electrode is implanted in the retina 2000 (as shown in fig. 4). As shown in FIGS. 4 and 5, two fixing members 200 (e.g., fixing nails) can effectively fix the micro-electrodes 110 to the surface of the retina through the two mounting holes 111. Alternatively, the mounting holes 111 on the flexible substrate may be patterned by a MEMS process, or may be implemented by machining or other possible means.
The micro-electrode 110 further includes an electrode region 112 and an elastic portion 113 between the two mounting holes 111. A plurality of stimulation electrodes 140 are provided within electrode region 112, the electrode region 112 and the stimulation electrodes 140 thereon being generally disposed proximate to a stimulated portion of the eyeball 3000, such as a foveal region 2200 (shown in fig. 5). Optionally, the number of the stimulation electrodes 140 is at least sixty, and of course, more stimulation electrodes 140 may be arranged according to different needs, for example, hundreds of stimulation electrodes 140 may also be arranged.
As shown in FIG. 2, the elastic portion 113 is connected to the electrode region 112, and the elastic portion 113 is deformable and stretchable at least in a length direction of a line connecting the two mounting holes 111, so that the micro-electrode 110 can be more closely attached to a corresponding surface of the retina 2000 by stretching the elastic portion 113 when the micro-electrode 110 is implanted into the retina 2000. Optionally, the elastic portion 113 has an avoidance hole 1133 avoiding the retinal nerve disk 2100.
The lead-in portion 130 is used to connect ASIC chips (application specific integrated circuits) within the electronic device 300. The connection portion 130 may be connected between the microelectrode 110 and the introduction portion 120 and is adapted to pass through a scleral incision in the wall of the eye (as shown in FIG. 4). The connection part 130 includes a plurality of leads (not shown) connected to the plurality of stimulation electrodes 140, respectively, so that each stimulation electrode 140 can be driven individually and electrical stimulation can be applied to a stimulated site, such as retina, with pertinence. The plurality of wires in the connection portion 130 may form one layer or may form a plurality of layers.
According to the utility model discloses flexible cable, through setting up two mounting holes 111, be convenient for carry out two fixed points to microelectrode 110 when implanting the retina to make microelectrode's atress even, the condition that also can not have the perk takes place, has guaranteed that the distance between stimulating electrode 140 and the retina 2000 surface is even, thereby has avoided big stimulating current to lead to the injury to the human body, simultaneously because the electric current reduces, has increased the live time to the battery of microelectrode 110 power supply. By providing the elastic portion 113, the micro-electrodes 110 can be ensured to be better attached to the corresponding surface of the retina 2000 when implanted in the retina 2000.
In some embodiments of the present invention, the flexible cable 100 is integrally manufactured by a MEMS process (micro-fabrication process-generic term for down to nano-scale, up to millimeter-scale micro-structure fabrication process), which may be made by chemical vapor deposition, sputtering, electroplating, evaporation, patterning, or a combination thereof.
In some alternative embodiments, the material of the flexible substrate is preferably PMMA (poly (methyl methacrylate) -polymethyl methacrylate), teflon, silicone, polyimide, Parylene (especially Parylene-C). By using a flexible substrate made of a flexible material, damage to an implantation site such as ocular tissue by the micro-electrode 110 during implantation can be suppressed. In addition, the curvature of the implantation part of the retina can be adapted through the flexible deformation of the flexible substrate, so that the plurality of stimulating electrodes 140 can be attached to the implantation part of the retina more fully, and a better electrical stimulation effect is realized.
In addition, the material of the stimulation electrode 140 and the wire in the connection portion 130 is preferably Au, Ag, Pt, Pd, Ti, or an alloy of any combination thereof. Since the above metals or their alloys have good biocompatibility, the stimulation electrode 140 composed of these materials can ensure biocompatibility. In addition, such stimulation electrodes 140 can be more suitable for use in implantable devices that have stringent biocompatibility requirements.
Further alternatively, the micro-electrode 110, the introduction part 130 and the connection part 120 may be constructed as an integrated structure. The flexible cable of a body structure is simple in structure and high in strength, and the required parts can be arranged only by opening holes in the surface of the flexible cable.
According to some embodiments of the present invention, the resilient portion 113 includes at least two flexible links 1131 and a closed end 1132. As shown in fig. 2, one end of each flexible chain 1131 is connected to the electrode region 112, and the flexible chain 1131 can be deformed and stretched in the length direction thereof, that is, the flexible chain 1131 can be deformed by an amount larger than its own size. The closed end 1132 is connected to the other end of the at least two flexible links 1131, and the closed end 1132 and the at least two flexible links 1131 define an avoidance hole 1133 therebetween adapted to correspond to the retinal nerve disk 2100.
Alternatively, as shown in fig. 2, the two mounting holes 111 of the micro-electrode 110 include a first mounting hole 111a and a second mounting hole 111b, the first mounting hole 111a is located on a side of the electrode region 112 away from the closed end 1132, and the second mounting hole 111b is located on the closed end 1132.
Thus, as shown in fig. 4 and 5, when the microelectrode 110 is implanted on the retina 2000 in the eyeball 3000 by two fixing members 200, the stimulation electrode 140 corresponds to the foveal region 2200 of the retina 2000, and the position of the retinal neural disc 2100 exactly corresponds to the avoiding hole 1133, so that the interference of the microelectrode on the retinal neural disc can be avoided, and the accurate visual perception effect can be ensured.
In some alternative embodiments of the present invention, as shown in fig. 2, the width of flexible cable 100 gradually increases in a direction toward electrode region 112 on a side away from closed end 1132; and the width of the closed end 1132 gradually decreases in a direction away from the electrode region 112. Therefore, the whole area of the microelectrode 110 is reduced, the microelectrode 110 is easy to implant into the eyeball 3000, damage to eyeball tissues caused by movement of the microelectrode 110 is reduced, and the cost can be reduced.
Further alternatively, as shown in fig. 2, the elastic portion 113 has a size in a width direction substantially equal to that of the electrode region 112, wherein the width direction is perpendicular to the length direction of the flexible chain 1131. The outer contour of the micro-electrode 110 is thereby smooth, and implantation of the micro-electrode 110 into the eyeball 3000 is facilitated.
The flexible chain 1131 may be configured as at least any one of the following structures: a helical elastic structure, a wave shape or a bellows-like structure, whereby stretching in the length direction thereof can be achieved. In an alternative embodiment, as shown in FIG. 2, the flexible link 1131 may be in the shape of a wave. Further alternatively, the closed end 1132 may also be configured as a helical spring structure or wave shape. In the example shown in FIG. 2, the closed end 1132 is also configured in an undulating shape.
In some embodiments of the present invention, the end of the closed end 1132 also has a clamping end 114, so as to facilitate clamping during the operation of the surgeon, which may facilitate the operation. The width of the holding end 114 is smaller than that of the electrode area 112, so that it is convenient for a tool such as tweezers to pick up. To further facilitate gripping, as in the example of fig. 3 and 4, the gripping end 114 may be disposed at an angle, optionally a 90 ° right angle, to the electrode region 112 during implantation.
According to some embodiments of the present invention, a plurality of stimulation electrodes 140 may be disposed in an array within the micro-electrodes 110, and the surfaces of the micro-electrodes that contact the retina 2000 are configured to substantially match the curvature of the corresponding portions of the retina 2000. In this way, the plurality of stimulating electrodes 140 may be more effectively attached to the retina 2000 of the eyeball 3000, in sufficient contact with the implanted portion of the retina 2000, such as the foveal region 2200, to produce more effective neural stimulation.
Optionally, the plurality of stimulation electrodes 140 may be arranged in an array manner of rows and columns, and the arrangement manner may be better suitable for the micro-electrodes 110 in which a larger number of stimulation electrodes 140 need to be arranged, so as to more effectively perform electrical stimulation on the implantation portion of the retina. Of course, the present invention is not limited thereto, and the plurality of stimulation electrodes 140 may also be arranged in other shapes, for example, expanding gradually outward from the stimulation electrodes disposed at the center-most region corresponding to the fovea or arranged sequentially around.
In some alternative examples, the ends of the stimulation electrodes 140 are exposed or partially exposed on one side of the flexible substrate to facilitate delivery of electrical stimulation pulses to retinal ganglion cells or bipolar cells. The amplitude of the stimulation pulse current may preferably be 200 muA-800 muA.
Further alternatively, each of the stimulation electrodes 140 may be formed in a cylindrical shape having substantially the same height and cross-sectional area, so that self-impedance between each of the stimulation electrodes 140 is substantially the same, thereby being capable of reducing adverse effects caused by impedance differences between the stimulation electrodes 140.
An implantation device 1000 for a retina according to an embodiment of the second aspect of the present invention includes: the flexible cable 100, the fixing member 200, the electronic device 300 and the first wireless annunciator 400 according to the above-described embodiments.
As shown in FIGS. 4 and 5, the flexible cable 100 further includes an introduction portion 120 and a connection portion 130, the connection portion 130 being connected between the micro-electrode 110 and the introduction portion 120 and adapted to pass through a scleral incision on the wall of the eyeball. The number of the fixing pieces 200 is two, and the two fixing pieces 200 fix the micro-electrodes 110 of the flexible cable 100 to the retina 2000 through the two mounting holes 111. Thus, two-point fixation of the microelectrode 110 can be conveniently carried out, so that the stress of the microelectrode is uniform, the situation of tilting does not occur, the uniform distance between the stimulating electrode 140 and the surface of the retina is ensured, and the injury to the human body caused by large stimulating current is avoided. The electrical pulse signals transmitted to the retina through the stimulation electrodes 140 stimulate neurons on the retina that remain functional and transmit the stimulation to the brain through the optic nerve, resulting in visual perception of the patient.
As shown in fig. 6, the fixing member 200 includes a shaft portion 210, an elastic member 220, a stopper portion 230, and a nail head 240. Shaft 210 is connected between stop 230 and stud 240, and stud 240 is used to pierce the surface of retina 2000. The elastic element 220 is disposed on the rod portion 210 in a penetrating manner, and two ends of the elastic element 220 respectively abut against the limiting portion 230 and the pad 250. Thus, after the two fixing members 200 fix the micro-electrode 110 on the surface of the retina at two points, the elastic member 220 may function as an elastic stop, and the pad 250 may contact the edge of the mounting hole 111 of the micro-electrode 110, thereby facilitating the transmission of pressure.
The electronic device 300 has a chip connected to the introduction part 120 to drive the plurality of stimulation electrodes 140. In some embodiments, the electronic device 300 may comprise an ASIC chip (application specific integrated circuit), a discrete raw device, or the like, for processing the received data signals to emit electrical stimulation pulses that drive the microelectrodes 110. The discrete primitive devices include electronic components such as capacitors, inductors, resistors, oscillators, and filters that may be provided according to circuit design. The connection portion 130 of the flexible cable 100 includes a plurality of conductive wires, and the connection portion 130 is connected to the electronic device 300 after passing through the wall of the eyeball.
The first wireless annunciator 400 is connected to the electronic device 300 for receiving data and energy from the outside and transmitting them to a chip within the electronic device 300. In some alternative embodiments, the electronic device 300 may be packaged integrally with the first wireless annunciator 400. Of course, the electronic device 300 may also be packaged separately from the first wireless annunciator 400. The first wireless annunciator 400 may include an internal wireless data coil and an internal wireless energy coil.
A process of implanting the retinal prosthesis implantation device 1000 according to an embodiment of the present invention into the eyeball 3000 will be described below with reference to fig. 4 and 5.
The physician holds the holding end 114 of the microelectrode 110 of the flexible cable 100 by a tool (e.g., forceps, not shown) and then applies the electrode regions 112 against the surface of the retina 2000. The nail holder (not shown) holds one fixing member 200, and first, feeds it into the eyeball 3000, passes the fixing member 200 through the mounting hole 111, the retina 2000, the choroid, and the sclera in this order, and then fixes the other fixing member 200, thereby fixing the micro-electrode 110 on the surface of the retina 2000.
The two fixing pieces 200 respectively penetrate through the two mounting holes 111 to fix the microelectrode 110 to the retina 2000, the whole microelectrode 110 is uniformly stressed, one end of the microelectrode cannot be tilted, the damage to the surface of the retina can be avoided, and the visual perception effect can be ensured.
Generally, each receptor at the foveal region 2200 of the retina 2000 is associated with a single bipolar cell, which in turn is associated with a single ganglion cell. Thus, each cone of foveal region 2200 has a direct path to the brain, which provides the brain with a precise location of input. Therefore, by attaching the micro-electrode 110 of the flexible cable 100 according to the embodiment of the present invention to the portion of the foveal region 2200, the stimulating electrode 140 can emit, for example, a bidirectional pulse current signal as an electrical stimulation signal. Here, interstitial fluid exists between the stimulation electrode 140 and the foveal region 2200, and the electrical stimulation signal delivered by the stimulation electrode 140 electrically stimulates ganglion cells of the retina or bipolar cells adjacent to the ganglion cells by conduction through the interstitial fluid. After the ganglion cells or bipolar cells are stimulated, the resulting stimulation signals create light sensation in the cerebral cortex via the visual pathway. After the stimulating electrode 140 is attached to the retina more closely, the stimulating efficiency of the stimulating electrode structure to the retina can be improved more effectively.
A retinal prosthesis according to an embodiment of the third aspect of the present invention includes the implant device 1000 according to the above embodiment and the external device 4000.
As shown in fig. 7, the external apparatus 4000 includes an image capturing unit 4100, a video processing unit 4200, and a second wireless annunciator 4300. The camera unit 4100 may be a camera, and the camera unit 4100 may be provided on a wearable device (e.g., glasses). It should be noted that the glasses may be replaced by other wearable devices such as a hat. The video processing unit 4200 may be worn elsewhere on the patient, for example, on a belt, clothing belt, etc.
The image pickup unit 4100 is electrically connected to the video processing unit 4200, and for example, the image pickup unit 4100 and the video processing unit 4200 may be connected by a cable. Alternatively, the camera on the glasses transmits video information to the video processing unit 4200, and the video processing unit 4200 converts the video signal into an electrical pulse data signal.
The video processing unit 4200 is electrically connected to the second wireless annunciator 4300, and the second wireless annunciator 4300 is electrically connected to the first wireless annunciator 400. The second wireless annunciator 4300 may include an external wireless data coil and an external wireless power coil, or may include only one coil and control data and power transmission through software. In some embodiments, the video processing unit 4200 may transmit the electrical impulse data signals back to the glasses through the cable, transmitting the data or energy to the first wireless annunciator 400 of the implant device 1000 through the second wireless annunciator 4300 mounted on the glasses.
In the description herein, references to the description of the term "one embodiment," "some embodiments," "an illustrative embodiment," "an example," "a specific example," or "some examples" or the like mean that a particular feature, structure, material, or characteristic described in connection with the embodiment or example is included in at least one embodiment or example of the present invention. In this specification, the schematic representations of the terms used above do not necessarily refer to the same embodiment or example.
While embodiments of the present invention have been shown and described, it will be understood by those of ordinary skill in the art that: various changes, modifications, substitutions and alterations can be made to the embodiments without departing from the principles and spirit of the invention, the scope of which is defined by the claims and their equivalents.

Claims (10)

1. A flexible cable for a retinal prosthesis, comprising:
the microelectrode, the microelectrode has two mounting holes, and including be located between two mounting holes the electrode zone and with the elasticity portion that the electrode zone links to each other, elasticity portion can at least be in the length direction of two mounting hole lines is out of shape tensile, elasticity portion has the hole of dodging that is suitable for corresponding retina nerve head, the electrode zone is equipped with the stimulation electrode that at least sixty arranged according to the law.
2. The flexible cable of the retinal prosthesis of claim 1, wherein the elastic portion comprises:
one end of each flexible chain is connected with the electrode region, and the flexible chains can be deformed and stretched in the length direction; and
a closed end connected at the other end of the at least two flexible chains, the closed end and the at least two flexible chains defining an avoidance hole therebetween adapted to correspond to a retinal neural disc.
3. The flexible cable of the retinal prosthesis of claim 2, wherein the two mounting holes comprise a first mounting hole and a second mounting hole, the first mounting hole being located on a side of the electrode zone away from the closed end, the second mounting hole being located on the closed end.
4. The flexible cable of the retinal prosthesis of claim 2, wherein the width of the flexible cable gradually increases in a direction toward the electrode zone on a side away from the closed end;
the width of the closed end gradually decreases in a direction away from the electrode region.
5. The flexible cable of the retinal prosthesis of claim 2, wherein the flexible chain is configured as at least any one of the following structures: a helical spring structure, a wave shape, or a bellows structure.
6. The flexible cable of the retinal prosthesis of claim 5, wherein the end of the closed end further has a clamping end adapted to be clamped.
7. The flexible cable of the retinal prosthesis of claim 2, wherein a dimension of the elastic portion in a width direction perpendicular to the length direction of the flexible chain is substantially equal to that of the electrode regions.
8. The flexible cable of the retinal prosthesis of any one of claims 1 to 7, wherein the plurality of stimulating electrodes are disposed in an array within the micro-electrodes, and the surfaces of the micro-electrodes in contact with the retina are configured to substantially match the curvature of the corresponding portion of the retina.
9. An implantation device for a retina, comprising:
the flexible cable according to any one of claims 1 to 8, further comprising an introduction portion and a connection portion connected between the micro-electrode and the introduction portion;
two fixing pieces for fixing the microelectrode of the flexible cable to the retina through the two mounting holes;
electronics having a chip connected to the lead-in portion to drive the plurality of stimulation electrodes;
a first wireless annunciator connected to the electronic device to receive image information obtained from the outside and to transmit the image information to the chip within the electronic device.
10. A retinal prosthesis, comprising:
an implant device of the retina according to claim 9;
an external device, the external device comprising: the camera shooting device comprises a camera shooting unit, a video processing unit and a second wireless annunciator, wherein the camera shooting unit is electrically connected with the video processing unit, the video processing unit is electrically connected with the second wireless annunciator, and the second wireless annunciator is electrically connected with the first wireless annunciator.
CN201920148824.1U 2019-01-28 2019-01-28 Retina prosthesis, implant device and flexible cable Active CN210542888U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201920148824.1U CN210542888U (en) 2019-01-28 2019-01-28 Retina prosthesis, implant device and flexible cable

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201920148824.1U CN210542888U (en) 2019-01-28 2019-01-28 Retina prosthesis, implant device and flexible cable

Publications (1)

Publication Number Publication Date
CN210542888U true CN210542888U (en) 2020-05-19

Family

ID=70664901

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201920148824.1U Active CN210542888U (en) 2019-01-28 2019-01-28 Retina prosthesis, implant device and flexible cable

Country Status (1)

Country Link
CN (1) CN210542888U (en)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109621195A (en) * 2019-01-28 2019-04-16 微智医疗器械有限公司 Retina prosthese, implanted device and flexible cable
CN111588984A (en) * 2020-05-27 2020-08-28 微智医疗器械有限公司 Implanted retina electric stimulator and implant thereof
CN112451856A (en) * 2020-12-10 2021-03-09 微智医疗器械有限公司 Flexible electrode, implantation device and implantation type retina electric stimulator
CN112716689A (en) * 2020-12-14 2021-04-30 微智医疗器械有限公司 Ophthalmic surgical instrument
WO2021238415A1 (en) * 2020-05-27 2021-12-02 微智医疗器械有限公司 Implant apparatus, and visual prosthesis having same

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109621195A (en) * 2019-01-28 2019-04-16 微智医疗器械有限公司 Retina prosthese, implanted device and flexible cable
CN109621195B (en) * 2019-01-28 2024-04-02 微智医疗器械有限公司 Retinal prosthesis, implantation device and flexible cable
CN111588984A (en) * 2020-05-27 2020-08-28 微智医疗器械有限公司 Implanted retina electric stimulator and implant thereof
WO2021238415A1 (en) * 2020-05-27 2021-12-02 微智医疗器械有限公司 Implant apparatus, and visual prosthesis having same
CN112451856A (en) * 2020-12-10 2021-03-09 微智医疗器械有限公司 Flexible electrode, implantation device and implantation type retina electric stimulator
CN112716689A (en) * 2020-12-14 2021-04-30 微智医疗器械有限公司 Ophthalmic surgical instrument
CN112716689B (en) * 2020-12-14 2023-09-15 微智医疗器械有限公司 Ophthalmic surgical instrument

Similar Documents

Publication Publication Date Title
CN210542888U (en) Retina prosthesis, implant device and flexible cable
CN109621195B (en) Retinal prosthesis, implantation device and flexible cable
US10722718B2 (en) Systems and methods for treatment of dry eye
US10328261B2 (en) Accommodation stimulation and recording device
EP2219728B1 (en) Electrode array for even neural pressure having multiple attachment points
US9072888B2 (en) Visual prosthesis with an improved electrode array adapted for foveal stimulation
JP2019213969A (en) Implantable microstimulating unit
CN106334258B (en) The stimulating electrode structure and artificial retina of artificial retina
EP1494753A1 (en) Variable pitch electrode array
Mokwa et al. Intraocular epiretinal prosthesis to restore vision in blind humans
CN108310625B (en) Bandage-free artificial retina system implantation device and artificial retina system
US20040127957A1 (en) Visual restoration aiding device
US20120271317A1 (en) Surgical Tool for Electrode Implantation
CN109821149B (en) Retinal prosthesis, implantation device and flexible cable
CN210355681U (en) Retina prosthesis, implant device and flexible cable
EP1951366B1 (en) Neural stimulation for increased contrast
CN209771110U (en) Retina prosthesis flexible cable and retina prosthesis
CN112451856A (en) Flexible electrode, implantation device and implantation type retina electric stimulator
AU2017204067B2 (en) Systems and methods for treatment of dry eye
WO2008020849A1 (en) Surgical tool for electrode implantation

Legal Events

Date Code Title Description
GR01 Patent grant
GR01 Patent grant