CN210340886U

CN210340886U - Trace bone marrow circulation enrichment device

Info

Publication number: CN210340886U
Application number: CN201920826374.7U
Authority: CN
Inventors: 侯天勇; 周江玲; 苟静; 杨鹏; 艾秋池; 许建中
Original assignee: First Affiliated Hospital of PLA Military Medical University
Current assignee: Nanfang Hospital; First Affiliated Hospital of PLA Military Medical University
Priority date: 2019-06-03
Filing date: 2019-06-03
Publication date: 2020-04-17
Anticipated expiration: 2029-06-03

Abstract

The utility model relates to the field of marrow enrichment, in particular to a trace marrow circulation enrichment device, which comprises a barrel body formed by connecting a front barrel body and a rear barrel body through screw threads, the front end of the front cylinder is provided with a first connecting nozzle communicated with the containing cavity of the front cylinder, the side wall of the rear end of the rear cylinder is provided with a second connecting nozzle communicated with the containing cavity of the rear cylinder, a piston is in sliding fit in the cylinder, the piston is fixed at the front end of a push-pull rod, the diameter of the push-pull rod is smaller than that of the piston, the push-pull rod is in sliding fit with a central hole arranged on the rear end wall of the rear cylinder body and extends out, a containing cavity is reserved between the push-pull rod and the inner wall of the rear cylinder body, the piston is eccentrically provided with an axial through hole, the front end of the axial through hole is provided with a one-way valve plate, the piston further comprises a hose, the front cylinder containing cavity is communicated with the rear cylinder containing cavity behind the piston through a hose to form a closed space. The device can meet the requirements of bone grafting patients and can not cause the waste of bone grafting materials and bone marrow quantity.

Description

Trace bone marrow circulation enrichment device

Technical Field

The utility model relates to a marrow enrichment field, concretely relates to trace marrow circulation enrichment device.

Background

The bone grafting treatment is a commonly used technology in orthopedics, the bone grafting material is the core of the bone grafting, and the most commonly adopted clinical bone of a patient is the clinical gold standard at present. However, the patient's autologous bone is taken out, which causes pain and infection in the bone-taking area, and especially when the amount of bone grafting material used in the spinal fusion and other surgeries is small, the patient needs to cut a few centimeters of mouth and take the ilium as the bone grafting material, which causes more trauma to the patient. Bone grafting materials such as allogeneic bone and synthetic bone can be adopted at present to avoid taking the autologous bone of a patient, but the materials lack active ingredients such as cells and factors capable of forming the bone, so that the risk of bone non-fusion caused by the materials being absorbed in vivo is high.

The bone marrow of human body contains stem cells and cytokines required for bone formation, and is often used for improving the bone forming activity of materials and treating bone nonunion. The traditional bone marrow application method is to inject bone marrow into a bone grafting area, but the bone marrow has fluidity, so that the bone marrow is difficult to stay at the local part of injection and seriously affects the effect; the osteogenic activity of the bone grafting material can be improved by adopting a method of soaking the bone grafting material by bone marrow, but the efficiency of enriching the bone marrow stem cells and cytokines in the bone grafting material is too low by adopting a simple soaking mode. Therefore, there is also a method of repeatedly filtering bone marrow in a bone graft material several times to improve osteogenic activity of the bone graft material.

However, the existing device for repeatedly filtering bone grafting materials by using bone marrow is too large in volume, for example, a bone growth negative pressure concentrator with the model of FWS-WJ-002A adopts a bone grafting material accommodating cup with the diameter of 5 cm, a spring with a telescopic function is used as a power device for repeatedly pumping, and due to the adoption of spring-driven pumping, at least 100 ml of bone marrow of a patient needs to be pumped each time and is filled into the cup, so that the bone marrow is soaked in the bone grafting material in the cup and is repeatedly filtered and enriched. However, since this device needs to extract at least 100 ml of bone marrow from the patient to filter the bone graft material, the bone graft material usually used starts with at least 20 cc to avoid bone marrow waste, and once the device is applied to bone graft material less than 5 cc, bone marrow is wasted greatly. However, the bone grafting material required by the spine fusion surgery only needs 2-4 cubic centimeters, if the existing bone growth negative pressure concentrator is adopted to repeatedly filter and concentrate the bone grafting material, the waste of the bone grafting material and bone marrow is caused, cost is not really saved, and physical and mental pressure and great economic burden are brought to a patient.

Disclosure of Invention

The utility model aims at providing a trace marrow circulation enrichment device to the not enough that prior art corresponds, its simple structure only needs through manual suction, just can accomplish the enrichment process of relapseing the filtration to small bone grafting material through trace marrow.

The utility model aims at adopting the following scheme to realize: a micro bone marrow circulation enrichment device comprises a barrel formed by connecting a front barrel and a rear barrel through threads, wherein the inner diameter of the barrel is 1.5-3 cm, the depth of a containing cavity of the front barrel is 2-3 cm, the depth of the containing cavity of the rear barrel is larger than that of the front barrel, a first connecting nozzle is arranged at the front end of the front barrel and communicated with the containing cavity of the front barrel, a second connecting nozzle is arranged on the side wall of the rear end of the rear barrel and communicated with the containing cavity of the rear barrel, a piston is in sliding fit in the barrel, the piston is fixed at the front end of a push-pull rod, the diameter of the push-pull rod is smaller than that of the piston, the push-pull rod is in sliding fit with and extends out of a central hole arranged on the rear end wall of the rear barrel, the containing cavity is reserved between the push-pull rod and the inner wall of the rear barrel, an axial through hole, the hose is used for connecting the first connecting nozzle with the second connecting nozzle outside the cylinder, and the front cylinder cavity is communicated with the rear cylinder cavity behind the piston through the hose to form a closed space.

The piston is provided with a plurality of eccentric axial through holes, and the inner diameter of each axial through hole is 2 mm.

The front end of the push-pull rod is fixedly connected with a supporting plate through a screw, the piston is fixedly connected on the supporting plate, and an eccentric through hole which is correspondingly communicated with an axial through hole on the piston is arranged on the supporting plate.

The end face of the piston, which is attached to the support plate, is provided with a central groove, and the central groove is used for yielding and centering the screw.

The cavity bottom of the cavity of the front barrel body is provided with a filter screen which is used for preventing bone grafting materials from entering the first connecting nozzle.

The one-way valve plate and the piston are integrally formed.

The hose adopts medical silicone tube.

And a sealing ring is arranged in a central hole formed in the rear end wall of the rear barrel.

The tail part of the push-pull rod is provided with a handle.

The outer wall of the cylinder body is provided with scales, and the unit is milliliter.

Compared with the prior art, the utility model discloses contain following beneficial effect:

the inner diameter of the cylinder is 1.5-3 cm, the depth of the containing cavity of the front cylinder is 2-3 cm, the depth of the containing cavity of the rear cylinder is larger than that of the front cylinder, the front end of the front cylinder is provided with a first connecting nozzle communicated with the containing cavity of the front cylinder, the side wall of the rear end of the rear cylinder is provided with a second connecting nozzle communicated with the containing cavity of the rear cylinder, a piston is in sliding fit in the cylinder, the piston is fixed at the front end of a push-pull rod, the diameter of the push-pull rod is smaller than that of the piston, the push-pull rod is in sliding fit with a central hole arranged on the rear end wall of the rear cylinder body and extends out, a containing cavity is reserved between the push-pull rod and the inner wall of the rear cylinder body, the piston is eccentrically provided with an axial through hole, the front end of the axial through hole is provided with a one-way valve plate, the piston further comprises a hose, the hose is used for connecting the first connecting nozzle and the second connecting nozzle outside the cylinder body, the front cylinder containing cavity is communicated with the rear cylinder containing cavity behind the piston through a hose to form a closed space. According to the structure, after the front cylinder body and the rear cylinder body are separated, 2-4 cubic centimeters of small bone grafting materials can be filled into the containing cavity of the front cylinder body, the front cylinder body and the rear cylinder body are screwed in a threaded fit mode, about 10 milliliters of small bone marrow obtained from a patient can be filled into the cylinder body through the first connecting nozzle or the second connecting nozzle, then the first connecting nozzle and the second connecting nozzle are connected through the hose, the push-pull rod of the piston is operated to push and pull repeatedly, the bone marrow can flow between the containing cavity of the front cylinder body and the containing cavity of the rear cylinder body under the driving of the piston, the bone grafting materials are filtered repeatedly, stem cells and cell factors in the bone marrow are enriched in the bone grafting materials, and the small bone grafting material bone marrow enrichment can be achieved only through the small bone marrow. Set up the check valve piece at the axial through-hole front end of piston, can be when the piston is pushed forward, the check valve piece is closed under the resistance, lets the marrow in piston the place ahead flow to the piston rear through the hose, when the piston draws backward, the check valve piece is opened under pressure, lets the marrow in piston rear can get into piston the place ahead from the axial through-hole and filters the bone grafting material, guarantees that the marrow in the barrel can flow and get up to filter the bone grafting material, reinforcing marrow enrichment effect.

The piston is provided with a plurality of eccentric axial through holes, and the inner diameter of each axial through hole is 2 mm, so that the bone marrow can pass through the axial through holes quickly.

The front end of the push-pull rod is fixedly connected with a supporting plate through a screw, the piston is fixedly connected on the supporting plate, and an eccentric through hole which is correspondingly communicated with an axial through hole on the piston is arranged on the supporting plate. The bearing plate can enhance the bearing strength of the piston, is beneficial to the work of the piston and prolongs the service life.

The end face of the piston, which is attached to the support plate, is provided with a central groove, and the central groove is used for yielding and centering the screw. The centering connection of the piston is facilitated, and the attachment and fixation of the piston and the supporting plate are also facilitated.

The cavity bottom of the cavity of the front barrel body is provided with a filter screen which can prevent bone grafting materials from entering the first connecting nozzle.

The hose adopts a medical silicone tube, has small reaction to human tissues, and can not cause foreign body reaction and inflammation of bone marrow.

A sealing ring is arranged in a central hole arranged on the rear end wall of the rear barrel body, so that the bone marrow in the barrel body is prevented from leaking outwards, and the outside splash water or dust can be prevented from invading into the barrel body.

The tail of the push-pull rod is provided with a handle, so that the convenience of manually pumping bone marrow is improved.

The outer wall of the cylinder body is provided with scales in milliliters, so that a user can conveniently observe the volume of collected bone marrow.

The utility model discloses though simple structure, but can carry out the enrichment to small bone grafting material with micro marrow, can not cause the marrow and plant the waste of bone grafting material to reinforcing marrow enrichment effect, the cost of manufacture is low simultaneously, can alleviate patient's economic burden, owing to adopt the marrow few, also can reduce patient's physical and mental pressure.

Drawings

FIG. 1 is a schematic sectional view of the present invention;

FIG. 2 is a schematic sectional view of the front barrel of the present invention;

fig. 3 is a schematic sectional structural view of the rear cylinder of the present invention;

FIG. 4 is a cross-sectional structural view of the piston of the present invention;

FIG. 5 is a schematic view of FIG. 4 taken along line A;

fig. 6 is a schematic cross-sectional view of the push-pull rod according to the present invention.

Detailed Description

As shown in fig. 1 to 6, the trace bone marrow circulation enrichment device comprises a front cylinder 1 and a rear cylinder 2 which are connected through a thread 3 to form a cylinder, wherein the cylinder is made of medical plastic or glass. The outer wall of barrel is equipped with the scale, and the unit is the milliliter, makes things convenient for the operator to accurately read the volume of liquid in the barrel. The inner diameter of the barrel is 1.5-3 cm, the depth of a cavity 1b of the front barrel 1 is 2-3 cm, the depth of a cavity 2b of the rear barrel 2 is larger than that of the front barrel 1, the depth of the cavity 2b of the rear barrel 2 can be three or four times of the depth of the cavity 1b of the front barrel 1, a first connecting nozzle 1a is arranged at the front end of the front barrel 1 and communicated with the cavity 1b of the front barrel 1, a second connecting nozzle 2a is arranged on the side wall of the rear end of the rear barrel 2 and communicated with the cavity 2b of the rear barrel 2, the first connecting nozzle 1a and the second connecting nozzle 2a are integrally formed with the barrel, and can also be fixedly connected in a hole formed in the barrel and can achieve the same purpose through bonding, fixing or threaded connection. The cavity bottom of the cavity 1b of the front cylinder 1 is provided with a filter screen 1c, and the filter screen 1c is used for preventing bone grafting materials from entering the first connecting nozzle 1 a. A piston 4 is in sliding fit in the cylinder, the piston 4 is fixed at the front end of a push-pull rod 5, the diameter of the push-pull rod 5 is smaller than that of the piston 4, the push-pull rod 5 is in sliding fit with a central hole 2c arranged on the rear end wall of the rear cylinder 2 and extends out, a sealing ring 2d is arranged in the central hole 2c arranged on the rear end wall of the rear cylinder 2, and the effect of sealing a gap between the push-pull rod 5 and the rear cylinder 2 in sliding fit through the sealing ring 2d is better. The tail part of the push-pull rod 5 is provided with a handle 5d, the handle 5d and the push-pull rod 5 are integrally formed, the handle 5d can also be fixedly connected to the tail part of the push-pull rod 5, and the same purpose can be achieved through bonding fixation or threaded connection. A cavity is reserved between the push-pull rod 5 and the inner wall of the rear cylinder 2, and the cavity can contain bone marrow flowing to the cavity under the driving of the reciprocating motion of the piston. An axial through hole 4a is eccentrically arranged on the piston 4, and a one-way valve plate 4b is arranged at the front end of the axial through hole 4 a. The piston 4 of this embodiment is provided with four eccentric axial through holes 4a, four axial through holes 4a are uniformly distributed on the piston 4, the inner diameter of each axial through hole 4a is 2 mm, the front ends of the four axial through holes 4a are provided with one-way valve plates 4b, and the one-way valve plates 4b and the piston 4 are integrally formed. The number of the axial through holes 4a in the piston 4 may also be two or three, or five or six, the number of the axial through holes 4a is small, the inner diameter of the axial through holes 4a may be larger, the number of the axial through holes 4a is larger, and the inner diameter of the axial through holes 4a may be smaller. The front end of the push-pull rod 5 is fixedly connected with a supporting plate 5c through a screw 5b, the diameter of the supporting plate 5c is a little bit smaller than that of the piston 4, so that the supporting strength of the piston can be guaranteed, and the piston can be guaranteed to be in full contact with the inner wall of the cylinder. The piston 4 is fixedly connected to a support plate 5c, the support plate 5c is provided with four eccentric through holes 5a which are correspondingly communicated with the axial through holes 4a of the piston 4, and the four eccentric through holes 5a of the support plate 5c are uniformly distributed on the support plate 5c and are correspondingly communicated with the axial through holes 4a of the piston 4. The end face of the piston 4, which is attached to the support plate 5c, is provided with a central groove 4c, and the central groove 4c is used for yielding and centering the screw 5 b. Still include a hose 6, hose 6 adopts medical silicone tube. The hose 6 is used for connecting the first connecting nozzle 1a and the second connecting nozzle 2a outside the cylinder, and the cavity 1b of the front cylinder 1 is communicated with the cavity 2b of the rear cylinder 2 behind the piston 4 through the hose 6 to form a closed space.

Before carrying out bone marrow circulation enrichment, firstly placing a small bone grafting material with the volume of 2-4 cubic centimeters in the containing cavity 1b of the front cylinder body 1, then screwing the rear cylinder body 2 and the front cylinder body 1 through the matching of the threads 3, then injecting a trace amount of bone marrow about 10 milliliters of bone marrow extracted from a patient from the first connecting nozzle 1a, and then connecting the first connecting nozzle 1a and the second connecting nozzle 2a by using a hose 6. The staff pushes the push-pull rod 5 to enable the piston 4 to move forwards to push the bone marrow, at the moment, the one-way valve plate 4b is in a closed state, the bone marrow flows into the containing cavity 2b of the rear cylinder 2 from the first connecting nozzle 1a through the hose 6 under the pushing of the piston 4, the push-pull rod 5 is pulled to enable the piston 4 to move backwards, the one-way valve plate 4b is opened, the bone marrow enters the containing cavity 1b of the front cylinder 1 from the containing cavity 2b of the rear cylinder 2 through the axial through hole 4a, and the operation is repeated, so that the bone marrow filters bone grafting materials in the circulation process, and stem cells and cell factors in the bone marrow are enriched in the bone grafting materials.

The above description is only a preferred embodiment of the present invention and is not intended to limit the present invention, and it is obvious that those skilled in the art can make various changes and modifications to the present invention without departing from the spirit and scope of the present invention. Thus, if such modifications and variations of the present invention fall within the scope of the claims and their equivalents, the present invention is also intended to include such modifications and variations.

Claims

1. The utility model provides a trace marrow circulation enrichment device which characterized in that: the circulation enrichment device comprises a cylinder body formed by connecting a front cylinder body (1) and a rear cylinder body (2) through a thread (3), wherein the inner diameter of the cylinder body is 1.5-3 cm, the depth of a containing cavity (1 b) of the front cylinder body (1) is 2-3 cm, the depth of a containing cavity (2 b) of the rear cylinder body (2) is larger than that of the front cylinder body (1), a first connecting nozzle (1 a) is arranged at the front end of the front cylinder body (1) and communicated with the containing cavity (1 b) of the front cylinder body (1), a second connecting nozzle (2 a) is arranged on the side wall of the rear end of the rear cylinder body (2) and communicated with the containing cavity (2 b) of the rear cylinder body (2), a piston (4) is in sliding fit in the cylinder body, the piston (4) is fixed at the front end of a push-pull rod (5), the diameter of the push-pull rod (5) is smaller than that of the piston (4), and the push-pull rod (5) is in sliding fit with a central hole (2, leave between this push-and-pull rod (5) and rear portion barrel (2) inner wall and hold the chamber, the eccentricity is equipped with axial through hole (4 a) on piston (4), axial through hole (4 a) front end is equipped with check valve piece (4 b), still includes a hose (6), hose (6) are used for connecting first connector (1 a) and second connector (2 a) outside the barrel, make front portion barrel (1) hold chamber (1 b) and rear portion barrel (2) at piston (4) rear hold chamber (2 b) intercommunication formation confined space through hose (6).

2. The micro bone marrow circulatory enrichment device of claim 1, wherein: the piston (4) is provided with a plurality of eccentric axial through holes (4 a), and the inner diameter of each axial through hole (4 a) is 2 mm.

3. The micro bone marrow circulatory enrichment device of claim 1, wherein: the front end of the push-pull rod (5) is fixedly connected with a supporting plate (5 c) through a screw (5 b), the piston (4) is fixedly connected to the supporting plate (5 c), and an eccentric through hole (5 a) is formed in the supporting plate (5 c) and correspondingly communicated with an axial through hole (4 a) in the piston (4).

4. The micro bone marrow circulatory enrichment device according to claim 3, wherein: the end face of the piston (4) attached to the support plate (5 c) is provided with a central groove (4 c), and the central groove (4 c) is used for yielding the screw (5 b) and forming centering.

5. The micro bone marrow circulatory enrichment device of claim 1, wherein: the cavity bottom of the cavity (1 b) of the front cylinder (1) is provided with a filter screen (1 c), and the filter screen (1 c) is used for preventing bone grafting materials from entering the first connecting nozzle (1 a).

6. The micro bone marrow circulatory enrichment device of claim 1, wherein: the check valve plate (4 b) and the piston (4) are integrally formed.

7. The micro bone marrow circulatory enrichment device of claim 1, wherein: the hose (6) adopts a medical silicone tube.

8. The micro bone marrow circulatory enrichment device of claim 1, wherein: and a sealing ring (2 d) is arranged in a central hole (2 c) formed in the rear end wall of the rear barrel (2).

9. The micro bone marrow circulatory enrichment device of claim 1, wherein: the tail part of the push-pull rod (5) is provided with a handle (5 d).

10. The micro bone marrow circulatory enrichment device of claim 1, wherein: the outer wall of the cylinder body is provided with scales, and the unit is milliliter.