CN210181054U - Fluorescent microfluidic detection pen - Google Patents
Fluorescent microfluidic detection pen Download PDFInfo
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- CN210181054U CN210181054U CN201921179061.3U CN201921179061U CN210181054U CN 210181054 U CN210181054 U CN 210181054U CN 201921179061 U CN201921179061 U CN 201921179061U CN 210181054 U CN210181054 U CN 210181054U
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Abstract
The utility model discloses a fluorescence micro-fluidic detection pen specifically is a device that need not carry out one-stop type detection with the help of other utensil or instrument, and detection cost is low, and is easy and simple to handle, and non professional medical personnel also can use, need not utilize and carry out sample detection after diluent dilution or the centrifugation. An end cover is sleeved and buckled outside the detection sample adding area, and a dilution bag is arranged in the end cover; the middle part of the microfluidic detection rod is provided with a microfluidic area, a marking reagent plate is arranged between the light source acquisition port and the siphon, and the front end of the end cover is elastically connected with a push button; two timing acquisition windows are arranged at the tail end of the microfluidic detection rod, the timing acquisition windows are in contact connection with the microfluidic area through the microfluidic detection rod adsorption cotton, and two contacts matched with the two timing acquisition windows arranged at the tail end of the microfluidic detection rod are arranged at the front end of the reagent card detection device.
Description
Technical Field
The utility model relates to a medical detection area specifically is a fluorescence micro-fluidic detection pen.
Background
Often need examine through the mode of drawing blood among the medical detection process, current technique can detect with finger tip blood, and is little to the harm of health, but need have high to the accuracy requirement of blood sample volume during quantitative determination, when testing with current test paper strip, need have the application of sample rifle ration to add the blood sample, and consumptive material such as application of sample rifle, suction head just can be accomplished to this kind of operation needs to use. In addition, the blood sample can be detected only by dilution or centrifugation, and can be detected by professional medical detection personnel, so that the process is complex and the operation difficulty is high.
SUMMERY OF THE UTILITY MODEL
Based on the above mentioned shortcomings in the prior art, the utility model provides a fluorescent microfluidic detection pen.
The utility model discloses an adopt following technical scheme to overcome above technical problem, specifically do:
a fluorescence micro-fluidic detection pen comprises a detection pen body, wherein a micro-fluidic detection rod and a reagent card detection device are respectively installed on the detection pen body, the rear part of the micro-fluidic detection rod is inserted with the front end of the detection pen body, a detection sample adding area is arranged at the front part of the micro-fluidic detection rod, a siphon tube for adding a sample is installed at the detection sample adding area, an end cover is sleeved and buckled outside the detection sample adding area, and a dilution bag is arranged in the end cover; the middle part of the microfluidic detection rod is provided with a microfluidic area, a plurality of light source acquisition ports are arranged at the microfluidic area at equal intervals, a marking reagent plate is arranged between the light source acquisition ports and the siphon, and the front end of the end cover is elastically connected with a push button; two timing acquisition windows are arranged at the tail end of the microfluidic detection rod, the timing acquisition windows are in contact connection with the microfluidic area through the microfluidic detection rod adsorption cotton, and two contacts matched with the two timing acquisition windows arranged at the tail end of the microfluidic detection rod are arranged at the front end of the reagent card detection device.
As a further aspect of the present invention: the reagent card detection device comprises a timing detection device, a control power supply device in signal connection with the timing detection device, a light excitation device and a light source acquisition device, wherein the light excitation device is electrically connected with the control power supply device.
As a further aspect of the present invention: and a receiver circuit board is fixed on one side of the light source acquisition device, which is close to the light excitation device, an optical filter is fixedly connected to the receiver circuit board, and a lens is arranged on the optical filter.
As a further aspect of the present invention: the light excitation device is provided with a light source, and the light source is electrically connected with the control power supply device through a light source circuit board.
As a further aspect of the present invention: the reagent card detection device further comprises a space temperature detection device and a heating plate, wherein the space temperature detection device is fixed in the detection pen body and is in signal connection with the heating plate, and the space temperature detection device is in signal connection with the light excitation device and the heating plate.
As a further aspect of the present invention: the external fixation of detection pen body has the display screen, and the display screen passes through control power supply unit signal connection light source collection system.
As a further aspect of the present invention: the display screen and the reagent card detection device are electrically connected with a power supply device fixed at the tail end of the detection pen body.
After the structure more than adopting, the utility model discloses compare in prior art, possess following advantage: the detection pen is matched with the detection rod, and the detection result is displayed in a text form through collection and processing; the space temperature detection device positioned in the shell detects the internal temperature of the detection pen, and the bottom plate heating device is started to heat when the temperature is lower than a set value without starting a detection function, so that the internal temperature of the cavity of the microfluidic detection pen is increased, and the influence of low temperature on a detection result is avoided; the timing is started after the micro-fluidic detection rod is matched and clamped with the detection pen, so that the timing accuracy is ensured, and the detection result is read at the optimal time to ensure the detection accuracy.
Drawings
Fig. 1 is a schematic structural diagram of a fluorescent microfluidic detection pen.
Fig. 2 is a front view of the fluorescent microfluidic test pen.
Fig. 3 is a schematic structural diagram of a microfluidic detection rod in a fluorescent microfluidic detection pen.
FIG. 4 is a side view of a light source collecting device and a light excitation device in the fluorescence micro-fluidic detection pen.
FIG. 5 is a partially enlarged view of the junction between the reagent card detection device and the timing acquisition window in the fluorescence micro-fluidic detection pen.
In the figure: 1-microfluidic detection rods; 2-a light source collecting device; 3-a light excitation device; 4-a reagent card detection device; 5-a display screen; 6-heating plate; 7-space temperature detection means; 8-a power supply device; 9-controlling the power supply device; 10-a timing detection device; 101-a timing acquisition window; 102-the microfluidic detection rod adsorbs cotton; 103-microfluidic region; 104-detection sample addition zone; 21-a lens; 22-an optical filter; 23-receiver circuit board; 31-a light source; 32-light source circuit board.
Detailed Description
In order to facilitate understanding of the present invention, the present invention will be described more fully hereinafter with reference to the accompanying drawings. The preferred embodiments of the present invention are shown in the drawings. The invention may, however, be embodied in many different forms and should not be construed as limited to the embodiments set forth herein. Rather, these embodiments are provided so that this disclosure will be thorough and complete.
In addition, an element of the present invention may be said to be "secured to" or "disposed on" another element, either directly on the other element or with intervening elements present. When an element is referred to as being "connected" to another element, it can be directly connected to the other element or intervening elements may also be present. The terms "vertical," "horizontal," "left," "right," and the like as used herein are for illustrative purposes only and do not represent the only embodiments.
Example 1
Referring to fig. 1 to 5, in an embodiment of the present invention, a fluorescent microfluidic detection pen includes a detection pen body, and a microfluidic detection rod 1 and a reagent card detection device 4 are respectively mounted on the detection pen body;
the rear part of the microfluidic detection rod 1 is inserted into the front end of the detection pen body, specifically, the front part of the microfluidic detection rod 1 is provided with a detection sample adding area 104, a siphon pipe for adding a sample is installed at the detection sample adding area 104, an end cover is sleeved and buckled outside the detection sample adding area 104, a dilution packet is arranged in the end cover, and after the end cover is buckled with the detection sample adding area 104 on the microfluidic detection rod 1, the front end of the microfluidic detection rod 1 punctures the dilution packet, so that a dilution liquid in the dilution packet is mixed with the sample in the siphon pipe, and the sample is diluted; the middle part of the microfluidic detection rod 1 is provided with a microfluidic area 103 for drainage, a plurality of light source collecting ports are equidistantly arranged at the microfluidic area 103, a labeled reagent plate is arranged between the light source collecting ports and a siphon, the front end of an end cover is elastically connected with a push button, when a sample is mixed with diluent, the mixed sample solution is conveyed towards the direction opposite to the push button by pressing the push button, when the sample solution flows through the labeled reagent plate, the sample solution is mixed and reacts with a labeled reagent on the labeled reagent plate, and the sample solution mixed and reacted with the labeled reagent and the diluent finally reaches the microfluidic area 103.
Furthermore, two timing acquisition windows 101 are arranged at the tail end of the microfluidic detection rod 1, the timing acquisition windows 101 are in contact connection with the microfluidic area 103 through microfluidic detection rod adsorption cotton 102, two contacts matched with the two timing acquisition windows 101 arranged at the tail end of the microfluidic detection rod 1 are arranged at the front end of the reagent card detection device 4, and the microfluidic area 103 is in contact with the timing acquisition windows 101 through the microfluidic detection rod adsorption cotton 102, so that a sample solution on the microfluidic area 103 is slowly drained to the dry microfluidic detection rod adsorption cotton 102 to soak the microfluidic detection rod adsorption cotton 102, and the reagent card detection device 4 has a conductive function, so that the contacts at the two timing acquisition windows 101 are electrified in a short circuit, and works to detect a mixed reactant of a labeled reagent, a diluent and a sample.
Still further, the reagent card detection device 4 comprises a timing detection device 10, a control power supply device 9 in signal connection with the timing detection device 10, a light excitation device 3 electrically connected with the control power supply device 9, and a light source acquisition device 2, wherein a receiver circuit board 23 is fixed on one side of the light source acquisition device 2 close to the light excitation device 3, an optical filter 22 is fixedly connected on the receiver circuit board 23, and a lens 21 is arranged on the optical filter 22; the light excitation device 3 is provided with a light source 31, the light source 31 is electrically connected with the control power supply device 9 through a light source circuit board 32, when the reagent card detection device 4 works, firstly, the timing detection device 10 is electrified, the timing detection device is electrified to start timing, after the timing reaches the preset detection time, the timing detection device 10 sends a signal to the control power supply device 9, the control power supply device 9 is connected with the light excitation device 3, so that the light excitation device 3 emits light with a specific wavelength and passes through the lens 21 and the optical filter 22, the light passing through the lens 21 and the filter 22 is absorbed by the light source collecting device 2, and if the sample contains the detecting substance, will react with the labeled reagent to produce a labeled substance, and will not react with the labeled reagent if the sample contains no detectable substance, and therefore, and judging whether the sample contains the detection object or not according to whether the light received by the light source collecting device 2 is influenced by the marker or not.
In order to ensure the accuracy of sample detection and prevent the detection result from being influenced by too low temperature, the reagent card detection device 4 further comprises a space temperature detection device 7 and a heating plate 6, wherein the space temperature detection device 7 is fixed in the detection pen body and is in signal connection with the heating plate 6, the space temperature detection device 7 is in signal connection with the light excitation device 3 and the heating plate 6, when the space temperature detection device 7 detects that the temperature in the detection pen body is too low, signals are sent to the light excitation device 3 and the heating plate 6 simultaneously, so that the light excitation device 3 does not work, and the heating plate 6 works to heat the interior of the detection pen body, and when the temperature reaches a set temperature, a signal is sent to the light excitation device 3 again to start detection; it should be noted that, when the temperature inside the test pen body is higher than the set temperature, the operation of the light excitation device 3 is not affected.
For the convenience of audio-visual reading testing result, the external fixation of detection pen body has display screen 5, and display screen 5 is through controlling power supply unit 9 signal connection light source collection system 2, and wherein, the equal electric connection of display screen 5 and reagent card detection device 4 is fixed in the power supply unit 8 that detects a body tail end, and the light signal that light source collection system 2 received is shown in signal transmission to display screen 5 through controlling power supply unit 9 conversion, is convenient for read.
According to the detailed description of the above embodiments, it is easy to understand that the working principle of the present invention is: after the end cover is buckled with the detection sample adding area 104 on the microfluidic detection rod 1, the front end of the microfluidic detection rod 1 punctures the diluting packet to mix the diluting liquid in the diluting packet with the sample in the siphon tube, the sample is diluted, after the sample is mixed with the diluting liquid, the mixed sample solution is conveyed towards the direction opposite to the push button by pressing the push button, when the sample solution flows through the marking reagent plate, the sample solution is mixed and reacts with the marking reagent on the marking reagent plate, the sample solution after the mixed reaction with the marking reagent and the diluting liquid finally reaches the microfluidic area 103, because the microfluidic area 103 is contacted with the timing acquisition window 101 through the microfluidic detection rod adsorption cotton 102, the sample solution on the microfluidic area 103 is slowly drained to the dry microfluidic detection rod adsorption cotton 102 to soak the microfluidic detection rod adsorption cotton 102, and has the function of electric conduction, thereby the contacts at the two timing acquisition windows 101 are short-circuited and electrified, the reagent card detection device 4 works to detect the mixed reactant of the marking reagent, the diluent and the sample, when the reagent card detection device 4 works, firstly the timing detection device 10 is electrified, the timing detection device is electrified to start timing, after the timing reaches the preset detection time, the timing detection device 10 sends a signal to the control power supply device 9, the control power supply device 9 is connected with the lamplight excitation device 3, the lamplight excitation device 3 sends out light with specific wavelength to pass through the lens 21 and the optical filter 22, the light passing through the lens 21 and the optical filter 22 is absorbed by the light source acquisition device 2, if the sample contains the detection substance, the light reacts with the marking reagent to generate the marking substance, if the sample does not contain the detection substance, the light does not react with the marking reagent, therefore, whether the sample contains the detection substance is judged according to whether the light received by the light source acquisition device 2 is influenced by the marking substance, when the space temperature detection device 7 detects that the internal temperature of the detection pen body is too low, signals are sent to the light excitation device 3 and the heating plate 6 at the same time, so that the light excitation device 3 does not work, the heating plate 6 works to heat the internal part of the detection pen body, and when the temperature reaches a set temperature, a signal is sent to the light excitation device 3 to start working detection; what need say, when the inside temperature of test pen body is higher than the settlement temperature, do not influence light excitation device 3 work, light signal that light source collection system 2 received converts the signal of telecommunication into through control power supply unit 9 and shows in carrying to display screen 5, is convenient for read.
The foregoing is illustrative of the preferred embodiments of the present invention only, and is not to be construed as limiting the claims. The present invention is not limited to the above embodiments, and the specific structure thereof is allowed to be changed. However, all changes which come within the scope of the independent claims of the invention are to be embraced therein.
Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs. The terminology used herein in the description of the invention is for the purpose of describing particular embodiments only and is not intended to be limiting of the invention. As used herein, the term "and/or" includes any and all combinations of one or more of the associated listed items.
Claims (7)
1. A fluorescent microfluidic detection pen comprises a detection pen body, wherein a microfluidic detection rod (1) and a reagent card detection device (4) are respectively arranged on the detection pen body, and the fluorescent microfluidic detection pen is characterized in that the rear part of the microfluidic detection rod (1) is spliced with the front end of the detection pen body, the front part of the microfluidic detection rod (1) is provided with a detection sample adding area (104), a siphon pipe for adding a sample is arranged at the detection sample adding area (104), the outside of the detection sample adding area (104) is sleeved and buckled with an end cover, and a dilution package is arranged in the end cover; a micro-fluidic area (103) is arranged in the middle of the micro-fluidic detection rod (1), a plurality of light source collecting ports are arranged in the micro-fluidic area (103) at equal intervals, a marking reagent plate is arranged between the light source collecting ports and the siphon, and the front end of the end cover is elastically connected with a push button; two timing acquisition windows (101) are arranged at the tail end of the microfluidic detection rod (1), the timing acquisition windows (101) are in contact connection with the microfluidic area (103) through microfluidic detection rod adsorption cotton (102), and two contacts matched with the two timing acquisition windows (101) arranged at the tail end of the microfluidic detection rod (1) are arranged at the front end of the reagent card detection device (4).
2. The fluorescence micro-fluidic detection pen according to claim 1, wherein the reagent card detection device (4) comprises a timing detection device (10), a control power supply device (9) in signal connection with the timing detection device (10), a light excitation device (3) and a light source collection device (2) electrically connected with the control power supply device (9).
3. The fluorescent microfluidic detection pen according to claim 2, wherein a receiver circuit board (23) is fixed on one side of the light source collection device (2) close to the light excitation device (3), an optical filter (22) is fixedly connected to the receiver circuit board (23), and a lens (21) is arranged on the optical filter (22).
4. The fluorescent microfluidic test pen according to claim 2, wherein the light excitation device (3) is provided with a light source (31), and the light source (31) is electrically connected with the control power supply device (9) through a light source circuit board (32).
5. The fluorescence micro-fluidic detection pen according to claim 2, wherein the reagent card detection device (4) further comprises a space temperature detection device (7) and a heating plate (6), wherein the space temperature detection device (7) is fixed inside the detection pen body and is in signal connection with the heating plate (6), and the space temperature detection device (7) is in signal connection with the light excitation device (3) and the heating plate (6).
6. The fluorescence micro-fluidic detection pen according to claim 2, characterized in that a display screen (5) is fixed outside the detection pen body, and the display screen (5) is in signal connection with the light source acquisition device (2) through a control power supply device (9).
7. The fluorescence micro-fluidic detection pen according to claim 6, wherein the display screen (5) and the reagent card detection device (4) are both electrically connected to a power supply device (8) fixed at the tail end of the detection pen body.
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CN201921179061.3U CN210181054U (en) | 2019-07-25 | 2019-07-25 | Fluorescent microfluidic detection pen |
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Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
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CN110275016A (en) * | 2019-07-25 | 2019-09-24 | 烟台简单生物技术有限公司 | A kind of fluorescence micro-fluidic detection pen and labelled reagent plate |
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Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
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CN110275016A (en) * | 2019-07-25 | 2019-09-24 | 烟台简单生物技术有限公司 | A kind of fluorescence micro-fluidic detection pen and labelled reagent plate |
CN110275016B (en) * | 2019-07-25 | 2023-11-17 | 山东新域生物技术有限公司 | Fluorescent microfluidic detection pen and marking reagent plate |
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Address after: 264006 room 643, plant 3, No. 32, Zhujiang Road, development zone, Yantai City, Shandong Province Patentee after: Shandong Xinyu Biotechnology Co.,Ltd. Address before: 264006 room 643, plant 3, No. 32, Zhujiang Road, development zone, Yantai City, Shandong Province Patentee before: Yantai Simple Biotechnology Co.,Ltd. |