CN210176863U - Fluorescent quantitative detector - Google Patents
Fluorescent quantitative detector Download PDFInfo
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- CN210176863U CN210176863U CN201920847877.2U CN201920847877U CN210176863U CN 210176863 U CN210176863 U CN 210176863U CN 201920847877 U CN201920847877 U CN 201920847877U CN 210176863 U CN210176863 U CN 210176863U
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Abstract
The utility model provides a fluorescence quantitative detector, which comprises a shell, a test tube supporting block, a fluorescence detection head and a translation driving mechanism, wherein a lofting opening for placing an eight-connected tube is arranged above the shell; the translation driving mechanism drives the fluorescence detection head to translate along the test tube supporting block, and the fluorescence detection head is used for carrying out quantitative detection on the target detected object in each hole of the eight-connected tube. A plurality of samples to be tested are respectively added into each tube body of the eight-connected tube, and only the hole site serial numbers of the eight-connected tube where the various samples are located need to be recorded, and the tube body does not need to be marked independently, so that the experiment operation is saved; the hole site samples are detected in sequence through one fluorescence detection head, so that the manufacturing cost is saved, and compared with the case of adopting a plurality of groups of independent fluorescence detection heads, the difference of a light path system between the fluorescence detection heads is avoided, and the accuracy of fluorescence quantitative detection is improved.
Description
Technical Field
The utility model relates to a biological test auxiliary equipment, especially a fluorescence quantitative determination appearance.
Background
The fluorescent quantitative detection technology is a method for quantitatively analyzing a target detected object by adding a fluorescent group into a PCR reaction system and utilizing fluorescent signal accumulation. At present, a fluorescence quantitative detector adopted in a laboratory generally only has one hole site, a group of comparative analysis of a plurality of samples is generally required in a general biological experiment, single-hole tubes carrying samples to be detected are required to be put into the detector one by one in sequence, and identification is required to be carried out on each single-hole tube to prevent confusion, so that the experiment operation is complicated, and the efficiency is low.
SUMMERY OF THE UTILITY MODEL
In order to overcome the defects of the prior art, the utility model aims to provide a fluorescence quantitative detector.
In order to achieve the above object, the technical solution of the present invention is: a fluorescence quantitative detector comprising:
the shell is provided with a lofting opening for placing the eight-connected pipe above;
the test tube support block is arranged in the shell and corresponds to the position right below the lofting opening, eight hole sites matched with the eight connecting tube bodies are arranged on the test tube support block, and lateral detection holes corresponding to the hole sites are formed in the test tube support block;
a fluorescence detection head comprising a light emission module and a fluorescence measurement module;
and the translation driving mechanism is used for driving the fluorescence detection head to translate along the test tube supporting block, enabling the fluorescence detection head to continuously stop at the position of each lateral detection hole, and quantitatively detecting the target detected object in each hole of the eight-connected tube through the fluorescence detection head.
Compared with the prior art, the utility model has the advantages that a plurality of samples to be tested are respectively added in the eight-connected-tube bodies, only the hole site serial numbers of the eight-connected-tube bodies where the various samples are located need to be recorded, and the tube bodies do not need to be marked independently, so that the experimental operation is saved; the hole site samples are detected in sequence through one fluorescence detection head, so that the manufacturing cost is saved, and compared with the case of adopting a plurality of groups of independent fluorescence detection heads, the difference of a light path system between the fluorescence detection heads is avoided, and the accuracy of fluorescence quantitative detection is improved.
Further, translation actuating mechanism includes translation guide rail, drive mechanism and driving motor, the translation guide rail sets up in the casing and parallel with the length direction that eight hole sites were arranged on the test tube tray, the fluorescence detects the head and installs on translation guide rail's the slider, driving motor drives through drive mechanism the fluorescence detects the head and removes along translation guide rail.
Furthermore, the transmission mechanism comprises a transmission belt, a driving belt wheel and a driven belt wheel, the transmission belt is wound between the driving belt wheel and the driven belt wheel, the driving belt wheel is installed on an output shaft of the driving motor, and the sliding block of the translation guide rail is connected to the transmission belt.
By adopting the preferable scheme, the stability of the translation of the fluorescence detection head along the test tube supporting block is improved.
Furthermore, the shell is also provided with a cover plate used for shielding the lofting opening.
Adopt above-mentioned preferred scheme, adopt the apron to shelter from eight hole pipe top light, improve fluorescence detection accuracy.
Further, the cover plate is openably and closably mounted on the housing by a hinge.
Further, the hinge is a damped hinge.
By adopting the preferable scheme, the cover plate can be kept at the opening angle position after being opened, does not fall down, and improves the customer experience.
Furthermore, a lifting plate is arranged above the test tube supporting block, the lifting plate is arranged on the test tube supporting block through guide post springs, eight through holes which are vertically opposite to eight hole sites on the test tube supporting block respectively are formed in the lifting plate, and when the cover plate is in an open state, the guide post springs lift the lifting plate to be higher than a lofting opening in the shell; when the cover plate is in a closed state, the cover plate presses the lifting plate into the lofting opening.
By adopting the preferable scheme, the tube body of the eight-connection tube penetrates through the through hole of the lifting plate, the lifting plate supports the eight-connection tube, after the detection is completed, the cover plate is opened, the guide pillar spring vertically and outwards ejects the lifting plate communicated with the eight-connection tube together, and the experimenter can conveniently take and place the eight-connection tube.
Furthermore, the cover plate and the shell are provided with magnets matched in position, and when the cover plate is in a closed state, the magnets on the cover plate and the magnets on the shell are attracted.
By adopting the preferable scheme, the cover plate covers the magnet suction force, and the cover plate is ensured to press the eight connecting pipes in place.
Furthermore, the shell is also provided with a circle of shading strips surrounding the lofting opening.
By adopting the preferable scheme, the shading performance is improved, and the influence of external light on detection data is reduced.
Furthermore, the volume specification of the eight-connecting pipe is 0.2ml × 8, the addition amount of a sample to be detected is reduced, and the reagent dosage is saved.
Further, all be equipped with two side direction inspection holes corresponding to every hole site on the test tube tray, two side direction inspection holes distribute in the both sides of test tube tray and all become 45 with test tube tray length direction, optical emission module and fluorescence survey module also distribute respectively in the both sides of test tube tray, optical emission module sends excitation light and shines on eight intraductal samples that await measuring through a side direction inspection hole, and the sample that awaits measuring receives the excitation of exciting light to produce fluorescence, fluorescence survey module carries out quantitative determination through another side direction inspection hole to fluorescence.
By adopting the preferable scheme, the incident channel is vertically crossed with the receiving channel, so that the influence of the incident light on the receiving channel through oblique incidence or reflection is reduced to the maximum extent.
Further, still include main control unit and touch-control display screen, main control unit locates in the casing, the touch-control display screen is installed on the casing, fluorescence detection head, translation actuating mechanism and touch-control display screen all with main control unit signal connection.
By adopting the preferable scheme, the touch display screen is convenient for a client to select and set parameters, and the detection data can be displayed more intuitively.
Drawings
In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings used in the description of the embodiments or the prior art will be briefly described below, it is obvious that the drawings in the following description are only some embodiments of the present invention, and for those skilled in the art, other drawings can be obtained according to these drawings without creative efforts.
FIG. 1 is a schematic structural diagram of an embodiment of the present invention;
FIG. 2 is a schematic view of the internal structure of the present invention;
FIG. 3 is a schematic top view of the structure of FIG. 2;
FIG. 4 is a cross-sectional view taken along line A-A of FIG. 3;
FIG. 5 is a schematic structural view of the test tube support block of the present invention;
FIG. 6 is a schematic structural view of the test tube support block of the present invention;
fig. 7 is a schematic structural diagram of the test tube support block of the present invention.
Names of corresponding parts represented by numerals and letters in the drawings:
1-a shell; 11-a lofting opening; 12-a cover plate; 2-eight connecting pipes; 3-test tube supporting block; 31-lateral detection holes; 32-lateral detection holes; 41-an optical transmit module; 42-a fluorescence assay module; 5-a translation driving mechanism; 51-a translation guide; 52-a driving pulley; 53-a driven pulley; 54-a transmission belt; 55-a drive motor; 6-lifting plate; 61-guide post spring; 7-shading strip; 8-touch control display screen; 9-main controller.
Detailed Description
The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative efforts belong to the protection scope of the present invention.
As shown in fig. 1 to 6, a fluorescence quantitative detector includes:
the device comprises a shell 1, wherein a lofting opening 11 for placing an eight-connecting pipe 2 is formed above the shell 1;
the test tube supporting block 3 is arranged in the shell 1 and corresponds to the position right below the lofting opening 11, eight hole sites matched with the tube body of the eight-connecting tube 2 are arranged on the test tube supporting block 3, and lateral detection holes 31/32 corresponding to each hole site are further formed in the test tube supporting block 3;
a fluorescence detection head including a light emission module 41 and a fluorescence measurement module 42;
and the translation driving mechanism 5 is used for driving the fluorescence detection head to translate along the test tube supporting block 3, enabling the fluorescence detection head to continuously stop at the position of each lateral detection hole, and quantitatively detecting the target detected object in each hole of the eight-connected tube through the fluorescence detection head.
The beneficial effect of adopting above-mentioned technical scheme is: a plurality of samples to be tested are respectively added into each tube body of the eight-connected tube, and only the hole site serial numbers of the eight-connected tube where the various samples are located need to be recorded, and the tube body does not need to be marked independently, so that the experiment operation is saved; the hole site samples are detected in sequence through one fluorescence detection head, so that the manufacturing cost is saved, and compared with the case of adopting a plurality of groups of independent fluorescence detection heads, the difference of a light path system between the fluorescence detection heads is avoided, and the accuracy of fluorescence quantitative detection is improved.
The utility model discloses fluorescence quantitative determination appearance's protection scope does not restrict and can only detect 1 eight sample that link the pipe simultaneously, also can carry out the sample fluorescence detection of a plurality of eight links pipes. Can place 1 or a plurality of eight in a lofting mouth and connect the pipe, can also set up a plurality of lofting mouths respectively, set up 1 or a plurality of eight in each lofting mouth and connect the pipe.
As shown in fig. 2 and 3, in other embodiments of the present invention, the translation driving mechanism 5 includes a translation guide rail 51, a transmission mechanism and a driving motor 55, the translation guide rail 51 is disposed in the housing and parallel to the length direction of the eight holes arranged on the test tube supporting block 3, the fluorescence detection head is mounted on the slider of the translation guide rail 51, and the driving motor 55 drives the fluorescence detection head to move along the translation guide rail 51 via the transmission mechanism. The transmission mechanism comprises a transmission belt 54, a driving pulley 52 and a driven pulley 53, the transmission belt 54 is wound between the driving pulley 52 and the driven pulley 53, the driving pulley 52 is installed on an output shaft of a driving motor 55, and a slide block of the translation guide rail 51 is connected to the transmission belt 54. The beneficial effect of adopting above-mentioned technical scheme is: the stability of the fluorescence detection head in translation along the test tube supporting block is improved.
In other embodiments of the present invention, as shown in fig. 1, the housing 1 is further provided with a cover plate 12 for shielding the lofting opening 11. The beneficial effect of adopting above-mentioned technical scheme is: and the cover plate is adopted to shield light rays above the eight-hole tube, so that the fluorescence detection accuracy is improved.
In other embodiments of the present invention, the cover plate 12 is openably and closably mounted on the housing by a hinge. The hinge is a damped hinge. The beneficial effect of adopting above-mentioned technical scheme is: the cover plate can be kept at an opening angle position after being opened, does not fall down, and improves the customer experience.
As shown in fig. 4-6, in other embodiments of the present invention, a lifting plate 6 is disposed above the test tube supporting block 3, the lifting plate 6 is mounted on the test tube supporting block 3 through a guide post spring 61, eight through holes are disposed on the lifting plate 6 and vertically aligned with eight holes on the test tube supporting block 3, respectively, and when the cover plate is in an open state, the guide post spring 61 lifts the lifting plate 6 higher than the lofting opening on the housing; when the cover is in the closed state, the cover presses the lifting plate 6 into the lofting opening. The beneficial effect of adopting above-mentioned technical scheme is: the body of eight even pipes passes the through-hole of lifter plate, and the lifter plate holds eight even pipes, and after detecting, open the apron, the guide pillar spring is vertical ejecting outwards together with eight even pipes of lifter plate intercommunication, and the experimenter of being convenient for gets and puts eight even pipes.
As shown in fig. 5-7, in other embodiments of the present invention, two lateral detection holes 31/32 are disposed on the test tube tray 3 corresponding to each hole position, the lateral detection holes 31/32 are distributed on both sides of the test tube tray 3 and all form 45 degrees with the length direction of the test tube tray, the light emitting module 41 emits exciting light to irradiate the sample to be measured in the eight connecting tubes through the lateral detection holes 31, the sample to be measured is excited by the exciting light to generate fluorescence, and the fluorescence measuring module 42 performs quantitative detection on the fluorescence through the lateral detection holes 32. The beneficial effect of adopting above-mentioned technical scheme is: the incident channel and the receiving channel are vertically crossed, so that the influence of the incident light on the receiving channel through oblique incidence or reflection is reduced to the maximum extent.
In other embodiments of the present invention, the cover plate and the housing are provided with magnets matching with each other in position, and when the cover plate is in a closed state, the magnets on the cover plate and the magnets on the housing are attracted to each other. The beneficial effect of adopting above-mentioned technical scheme is: the cover plate covers the magnet suction force to ensure that the cover plate presses the eight connecting pipes in place.
In other embodiments of the present invention, as shown in fig. 1, a circle of light shielding strips 7 surrounding the lofting opening 11 is further provided on the housing 1. The beneficial effect of adopting above-mentioned technical scheme is: the shading performance is improved, and the influence of external light on detection data is reduced.
In other embodiments of the present invention, the volume specification of the eight-connecting pipe is 0.2ml x 8, which reduces the addition of the sample to be tested and saves the reagent amount.
As shown in fig. 1-3, in other embodiments of the present invention, the present invention further comprises a main controller 9 and a touch display screen 8, the main controller 9 is disposed in the casing 1, the touch display screen 8 is mounted on the casing, and the fluorescence detection head, the translation driving mechanism 5 and the touch display screen 8 are all in signal connection with the main controller 9. The beneficial effect of adopting above-mentioned technical scheme is: the touch display screen is convenient for a client to select and set parameters, and detection data can be displayed more intuitively.
The above embodiments are only for illustrating the technical conception and the features of the present invention, and the purpose thereof is to enable those skilled in the art to understand the contents of the present invention and implement the present invention, and the protection scope of the present invention can not be limited thereby, and all equivalent changes or modifications made according to the spirit of the present invention should be covered in the protection scope of the present invention.
Claims (10)
1. A fluorescence quantitative detector, comprising:
the shell is provided with a lofting opening for placing the eight-connected pipe above;
the test tube support block is arranged in the shell and corresponds to the position right below the lofting opening, eight hole sites matched with the eight connecting tube bodies are arranged on the test tube support block, and lateral detection holes corresponding to the hole sites are formed in the test tube support block;
a fluorescence detection head comprising a light emission module and a fluorescence measurement module;
and the translation driving mechanism is used for driving the fluorescence detection head to translate along the test tube supporting block, enabling the fluorescence detection head to continuously stop at the position of each lateral detection hole, and quantitatively detecting the target detected object in each hole of the eight-connected tube through the fluorescence detection head.
2. The fluorescence quantitative detector according to claim 1, wherein the translational driving mechanism comprises a translational guide rail, a transmission mechanism and a driving motor, the translational guide rail is disposed in the housing and parallel to the length direction of the eight hole sites arranged on the test tube support block, the fluorescence detection head is mounted on a slide block of the translational guide rail, and the driving motor drives the fluorescence detection head to move along the translational guide rail through the transmission mechanism.
3. The fluorescence quantitative detector of claim 2, wherein the transmission mechanism comprises a transmission belt, a driving pulley and a driven pulley, the transmission belt is wound between the driving pulley and the driven pulley, the driving pulley is mounted on an output shaft of the driving motor, and the slide block of the translation guide rail is connected to the transmission belt.
4. The fluorescence quantitative detector according to claim 1, wherein the housing further has a cover plate for covering the lofting opening.
5. The fluorescence quantitative detector according to claim 4, wherein the cover plate is openably and closably mounted on the housing by a damping hinge.
6. The fluorescence quantitative detector according to claim 4, wherein a lifting plate is disposed above the test tube holder, the lifting plate is mounted on the test tube holder through a guide post spring, the lifting plate is provided with eight through holes vertically aligned with the eight holes on the test tube holder, respectively, and the guide post spring lifts the lifting plate above the lofting opening of the housing when the cover plate is in the open state; when the cover plate is in a closed state, the cover plate presses the lifting plate into the lofting opening.
7. The fluorescence quantitative detector of claim 6, wherein the cover and the housing have magnets at matching positions, and when the cover is closed, the magnets on the cover and the housing attract each other.
8. The fluorescence quantitative detector of claim 6, wherein the housing further comprises a light shielding strip surrounding the lofting opening.
9. The fluorescence quantitative detector according to claim 1, wherein two lateral detection holes are formed in the tube tray corresponding to each hole, the two lateral detection holes are distributed on two sides of the tube tray and form a 45 ° angle with the length direction of the tube tray, the light emitting module and the fluorescence measuring module are distributed on two sides of the tube tray, the light emitting module emits excitation light to irradiate the sample to be measured in the eight-link tube through one lateral detection hole, the sample to be measured is excited by the excitation light to generate fluorescence, and the fluorescence measuring module performs quantitative detection on the fluorescence through the other lateral detection hole.
10. The fluorescence quantitative detector according to claim 1, further comprising a main controller and a touch display screen, wherein the main controller is disposed in the housing, the touch display screen is mounted on the housing, and the fluorescence detection head, the translation driving mechanism and the touch display screen are all in signal connection with the main controller.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201920847877.2U CN210176863U (en) | 2019-06-06 | 2019-06-06 | Fluorescent quantitative detector |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201920847877.2U CN210176863U (en) | 2019-06-06 | 2019-06-06 | Fluorescent quantitative detector |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN210176863U true CN210176863U (en) | 2020-03-24 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201920847877.2U Active CN210176863U (en) | 2019-06-06 | 2019-06-06 | Fluorescent quantitative detector |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN210176863U (en) |
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2019
- 2019-06-06 CN CN201920847877.2U patent/CN210176863U/en active Active
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